GO ID |
Ontology |
GO Term |
Term Definition |
Proteins |
GO:0097105
|
BP
|
presynaptic membrane assembly
|
The aggregation, arrangement and bonding together of a set of components to form a presynaptic membrane, including any proteins associated with the membrane, but excluding other cellular components. A presynaptic membrane is a specialized area of membrane of the axon terminal that faces the plasma membrane of the neuron or muscle fiber with which the axon terminal establishes a synaptic junction.
|
PTPRD,
PTEN,
NLGN4X,
NLGN1
|
GO:0097107
|
BP
|
postsynaptic density assembly
|
The aggregation, arrangement and bonding together of a set of components to form a postsynaptic density, a region that lies adjacent to the cytoplasmic face of the postsynaptic membrane at excitatory synapse.
|
PTEN
|
GO:0097111
|
BP
|
endoplasmic reticulum-Golgi intermediate compartment organization
|
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endoplasmic reticulum (ER)-Golgi intermediate compartment.
|
GBF1
|
GO:0097112
|
BP
|
gamma-aminobutyric acid receptor clustering
|
The receptor clustering process in which gamma-aminobutyric acid (GABA) receptors are localized to distinct domains in the cell membrane.
|
GLRB,
GPHN
|
GO:0097113
|
BP
|
AMPA glutamate receptor clustering
|
The glutamate receptor clustering process in which alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors are localized to distinct domains in the cell membrane.
|
APOE,
DLG4,
NLGN1
|
GO:0097114
|
BP
|
NMDA glutamate receptor clustering
|
The receptor clustering process in which N-methyl-D-aspartate (NMDA) receptors are localized to distinct domains in the cell membrane.
|
APOE,
NLGN1
|
GO:0097115
|
BP
|
neurexin clustering involved in presynaptic membrane assembly
|
The receptor clustering process involved in assembly of the presynaptic membrane in which neurexins are localized to distinct domains in the cell membrane. Neurexins are synaptic cell surface proteins which act as cell recognition molecules at nerve terminals.
|
NLGN1
|
GO:0097116
|
BP
|
gephyrin clustering involved in postsynaptic density assembly
|
The clustering process in which gephyrin molecules are localized to distinct domains in the postsynaptic density as part of postsynaptic density assembly. Gephyrin is a component of the postsynaptic protein network of inhibitory synapses.
|
NRXN1
|
GO:0097118
|
BP
|
neuroligin clustering involved in postsynaptic membrane assembly
|
The receptor clustering process involved in assembly of the postsynaptic membrane in which neuroligins are localized to distinct domains in the cell membrane. Neuroligins are neuronal cell surface proteins on the postsynaptic membrane that mediate synapse formation between neurons.
|
CDH2,
MAGI2,
NRXN1
|
GO:0097119
|
BP
|
postsynaptic density protein 95 clustering
|
The clustering process in which postsynaptic density protein 95 (PSD-95) molecules are localized to distinct domains in the cell membrane. PSD-95 is mostly located in the post synaptic density of neurons, and is involved in anchoring synaptic proteins.
|
NLGN1,
NRXN1
|
GO:0097120
|
BP
|
receptor localization to synapse
|
Any process in which a receptor is transported to, and/or maintained at the synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell.
|
DLG4,
DLG1,
NLGN1
|
GO:0097150
|
BP
|
neuronal stem cell population maintenance
|
Any process in by an organism or tissue maintains a population of neuronal stem cells.
|
FOXO3,
CDH2,
NOTCH1,
JAG1,
FOXO1,
HES1,
PCM1,
HOOK3,
ASPM,
PROX1,
FANCD2,
MMP24
|
GO:0097151
|
BP
|
positive regulation of inhibitory postsynaptic potential
|
Any process that activates or increases the frequency, rate or extent of inhibitory postsynaptic potential (IPSP). IPSP is a temporary decrease in postsynaptic membrane potential due to the flow of negatively charged ions into the postsynaptic cell. The flow of ions that causes an IPSP is an inhibitory postsynaptic current (IPSC) and makes it more difficult for the neuron to fire an action potential.
|
ABAT,
IGSF9B,
RIMS2
|
GO:0097152
|
BP
|
mesenchymal cell apoptotic process
|
Any apoptotic process in a mesenchymal cell. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types.
|
TBX1
|
GO:0097154
|
BP
|
GABAergic neuron differentiation
|
The process in which a neuroblast acquires the specialized structural and functional features of a GABAergic neuron.
|
INHBA
|
GO:0097155
|
BP
|
fasciculation of sensory neuron axon
|
The collection of sensory neuron axons into a bundle of rods, known as a fascicle.
|
EPHA3,
EPHA4
|
GO:0097156
|
BP
|
fasciculation of motor neuron axon
|
The collection of motor neuron axons into a bundle of rods, known as a fascicle.
|
EPHA3,
EPHA4
|
GO:0097167
|
BP
|
circadian regulation of translation
|
Any process that modulates the frequency, rate or extent of mRNA translation with a regularity of approximately 24 hours.
|
PER1,
HNRNPD,
RBM4
|
GO:0097178
|
BP
|
ruffle assembly
|
The aggregation, arrangement and bonding together of a set of components to form a ruffle, a projection at the leading edge of a crawling cell; the protrusions are supported by a microfilament meshwork. The formation of ruffles (also called membrane ruffling) is thought to be controlled by a group of enzymes known as Rho GTPases, specifically RhoA, Rac1 and cdc42.
|
RAC1,
ARHGEF26,
INPP5K
|
GO:0097186
|
BP
|
amelogenesis
|
The process whose specific outcome is the formation of tooth enamel, occurring in two stages: secretory stage and maturation stage.
|
ITGB4,
ITGA6,
PERP,
CSF3R
|
GO:0097187
|
BP
|
dentinogenesis
|
The process whose specific outcome is the formation of dentin, the mineralized tissue that constitutes the major bulk of teeth. Dentin may be one of three types: primary dentin, secondary dentin, and tertiary dentin.
|
FAM20C,
HTRA1
|
GO:0097190
|
BP
|
apoptotic signaling pathway
|
A series of molecular signals which triggers the apoptotic death of a cell. The pathway starts with reception of a signal, and ends when the execution phase of apoptosis is triggered.
|
DAPL1,
TLR4,
HIP1,
TNFRSF11B,
TLR3,
DAPK3,
PDCD6,
TNFRSF21,
ANXA6,
NGFR,
CD14,
CD28,
PRKCA,
TNFRSF1B,
FAS,
TNFRSF8,
ADORA1,
IFI27,
DAP,
DAP3,
DAPK1,
CAV1,
PPARD,
BAX,
FADD,
RIPK1,
FASTK,
CASP8,
PTGIS,
TNFRSF25,
MOAP1,
PAWR,
P2RX4,
MAP3K5,
DIDO1,
TM2D1,
UACA,
NDUFA13,
TNFRSF11A
|
GO:0097191
|
BP
|
extrinsic apoptotic signaling pathway
|
A series of molecular signals in which a signal is conveyed from the cell surface to trigger the apoptotic death of a cell. The pathway starts with either a ligand binding to a cell surface receptor, or a ligand being withdrawn from a cell surface receptor (e.g. in the case of signaling by dependence receptors), and ends when the execution phase of apoptosis is triggered.
|
SIVA1,
TLR3,
JAK2,
IL33,
TGFB1,
TNF,
KRT18,
KRT8,
INHBA,
IL6R,
TNFRSF1B,
FAS,
CD27,
G0S2,
IL12A,
ACVR1B,
TGFB2,
SMAD3,
BAX,
MLLT11,
FADD,
RIPK1,
CASP8,
TRADD,
BAD,
CIB1,
TNFRSF12A,
NDUFA13,
PARP2
|
GO:0097192
|
BP
|
extrinsic apoptotic signaling pathway in absence of ligand
|
A series of molecular signals in which a signal is conveyed from the cell surface to trigger the apoptotic death of a cell. The pathway starts with withdrawal of a ligand from a cell surface receptor, and ends when the execution phase of apoptosis is triggered.
|
EYA2,
BCL2L11,
FOXO3,
IL1A,
IL1B,
ITGAV,
BCL2,
KITLG,
ERBB3,
FAS,
GSK3B,
CASP9,
BAX,
MCL1,
FADD,
BCL2L2,
BAD,
MOAP1,
MKNK2,
BOK
|
GO:0097193
|
BP
|
intrinsic apoptotic signaling pathway
|
A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway starts with reception of an intracellular signal (e.g. DNA damage, endoplasmic reticulum stress, oxidative stress etc.), and ends when the execution phase of apoptosis is triggered. The intrinsic apoptotic signaling pathway is crucially regulated by permeabilization of the mitochondrial outer membrane (MOMP).
|
DDX3X,
NBN,
NOL3,
TP53,
CD24,
CDKN1A,
PPM1F,
CASP4,
MSH6,
CYCS,
BAX,
MLLT11,
CUL2,
CUL3,
CUL4A,
PMAIP1,
BAD,
CUL5,
LGALS12,
APOPT1,
BBC3,
HIPK2
|
GO:0097194
|
BP
|
execution phase of apoptosis
|
A stage of the apoptotic process that starts with the controlled breakdown of the cell through the action of effector caspases or other effector molecules (e.g. cathepsins, calpains etc.). Key steps of the execution phase are rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died.
|
CFLAR,
AKT1,
CASP8,
STK24
|
GO:0097195
|
BP
|
pilomotor reflex
|
The reflex process in which the arrectores pilorum (hair follicle) muscles contract and cause the hair to stand erect.
|
ADRA1A
|
GO:0097201
|
BP
|
negative regulation of transcription from RNA polymerase II promoter in response to stress
|
Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
|
IMPACT
|
GO:0097202
|
BP
|
activation of cysteine-type endopeptidase activity
|
Any process that initiates the activity of the inactive enzyme cysteine-type endopeptidase.
|
ASPH,
FADD,
CASP8,
IFI16,
BAD,
CYFIP2,
PERP,
PYCARD
|
GO:0097205
|
BP
|
renal filtration
|
A renal system process in which fluid circulating through the body is filtered through a barrier system.
|
ITGA3
|
GO:0097211
|
BP
|
cellular response to gonadotropin-releasing hormone
|
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gonadotropin-releasing hormone stimulus. Gonadotropin-releasing hormone (GnRH) is a peptide hormone responsible for the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary. GnRH is synthesized and released by the hypothalamus.
|
GNRHR,
MGARP
|
GO:0097212
|
BP
|
lysosomal membrane organization
|
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lysosomal membrane. A lysosomal membrane is the lipid bilayer surrounding the lysosome and separating its contents from the cell cytoplasm.
|
ARF1
|
GO:0097214
|
BP
|
positive regulation of lysosomal membrane permeability
|
Any process that increases the frequency, rate or extent of the passage or uptake of molecules by the lysosomal membrane.
|
MT3
|
GO:0097222
|
BP
|
mitochondrial mRNA polyadenylation
|
The enzymatic addition of a sequence of 40-60 adenylyl residues at the 3' end of a eukaryotic mitochondrial mRNA primary transcript. Mitochondria contain both stabilizing and destabilizing poly(A) tails.
|
PNPT1
|
GO:0097237
|
BP
|
cellular response to toxic substance
|
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a toxic stimulus.
|
PARK2,
ABTB2,
PINK1
|
GO:0097238
|
BP
|
cellular response to methylglyoxal
|
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylglyoxal stimulus. Methylglyoxal is a 2-oxoaldehyde derived from propanal.
|
AKR1B1
|
GO:0097241
|
BP
|
hematopoietic stem cell migration to bone marrow
|
The orderly movement of a hematopoietic stem cell into the bone marrow, and its subsequent positioning within defined functional compartments in that microenvironment. A hematopoietic stem cell is a cell from which all cells of the lymphoid and myeloid lineages develop, including blood cells and cells of the immune system.
|
GPLD1,
GAS6
|
GO:0097252
|
BP
|
oligodendrocyte apoptotic process
|
Any apoptotic process in an oligodendrocyte. Oligodendrocytes belong to a class of large neuroglial (macroglial) cells in the central nervous system, where they form the insulating myelin sheath of axons.
|
TNFRSF21,
TP53
|
GO:0097264
|
BP
|
self proteolysis
|
The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their own peptide bonds.
|
CAPN3,
TENM4,
TMPRSS6,
TENM3
|
GO:0097267
|
BP
|
omega-hydroxylase P450 pathway
|
The chemical reactions and pathways by which arachidonic acid is converted to other compounds initially by omega-hydroxylation.
|
CYP1A1,
CYP2C9,
CYP1B1,
CYP2U1
|
GO:0097274
|
BP
|
urea homeostasis
|
Any biological process involved in the maintenance of an internal steady state of urea.
|
SLC25A23
|
GO:0097278
|
BP
|
complement-dependent cytotoxicity
|
Lysis of a cell resulting from triggering of the complement cascade. An example can be seen with complement activation and subsequent lysis of a bacterial cell as a result of the binding of IgM to the cell surface followed by the binding of complement proteins to that antibody.
|
RAB27A
|
GO:0097284
|
BP
|
hepatocyte apoptotic process
|
Any apoptotic process in a hepatocyte, the main structural component of the liver.
|
KRT18,
KRT8,
RB1,
FAS,
PIK3CG,
BID,
STK4
|
GO:0097286
|
BP
|
iron ion import
|
The directed movement of iron ions into a cell or organelle.
|
TFRC,
MFI2
|
GO:0097296
|
BP
|
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
|
Any process that initiates the activity of an inactive cysteine-type endopeptidase involved in the apoptotic signaling pathway.
|
JAK2,
FAS,
TNFSF10,
SMAD3,
BAX,
FADD,
RIPK1,
CASP8,
TRADD
|
GO:0097300
|
BP
|
programmed necrotic cell death
|
A necrotic cell death process that results from the activation of endogenous cellular processes, such as signaling involving death domain receptors or Toll-like receptors.
|
CASP1,
MAP3K5
|
GO:0097310
|
BP
|
cap2 mRNA methylation
|
Methylation of the ribose of the first and second nucleotides of a 5'-capped mRNA.
|
CMTR2
|
GO:0097320
|
BP
|
membrane tubulation
|
A modification in a plasma membrane resulting in formation of a tubular invagination.
|
FNBP1L,
SNX33,
PACSIN1,
BIN2,
SNX9
|
GO:0097324
|
BP
|
melanocyte migration
|
The orderly movement of melanocytes from one site to another, often during the development of a multicellular organism. A melanocyte is a pigment cell derived from the neural crest. It contains melanin-filled pigment granules, which give a brown to black appearance.
|
ZEB2,
KIT
|
GO:0097325
|
BP
|
melanocyte proliferation
|
The multiplication or reproduction of melanocytes, resulting in the expansion of a cell population. A melanocyte is a pigment cell derived from the neural crest. It contains melanin-filled pigment granules, which give a brown to black appearance.
|
WNT5A
|
GO:0097326
|
BP
|
melanocyte adhesion
|
The attachment of a melanocyte to another cell via adhesion molecules.
|
KIT
|
GO:0097327
|
BP
|
response to antineoplastic agent
|
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antineoplastic agent stimulus. An antineoplastic agent is a substance that inhibits or prevents the proliferation of neoplasms.
|
RAP1A
|
GO:0097332
|
BP
|
response to antipsychotic drug
|
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antipsychotic drug stimulus. Antipsychotic drugs are agents that control agitated psychotic behaviour, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect.
|
PRKAR2B
|
GO:0097338
|
BP
|
response to clozapine
|
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a clozapine stimulus.
|
PRKAR2B
|
GO:0097343
|
BP
|
ripoptosome assembly
|
The aggregation, arrangement and bonding together of a set of components to form a ripoptosome, a protein complex whose formation can induce an extrinsic apoptotic signaling pathway or a necroptotic signaling pathway. The composition of this protein complex may depend on several factors including nature of the signal, cell type and more.
|
RIPK1
|
GO:0097345
|
BP
|
mitochondrial outer membrane permeabilization
|
The process by which the mitochondrial outer membrane becomes permeable to the passing of proteins and other molecules from the intermembrane space to the cytosol as part of the apoptotic signaling pathway.
|
EYA2,
BNIP3L,
BID,
BNIP3
|
GO:0097350
|
BP
|
neutrophil clearance
|
The selective elimination of senescent neutrophils from the body by autoregulatory mechanisms.
|
ANXA1,
HMGB1
|
GO:0097352
|
BP
|
autophagosome maturation
|
The process in which autophagosomes, double-membraned vacuoles containing cytoplasmic material fuse with a vacuole (yeast) or lysosome (e.g. mammals and insects). In the case of yeast, inner membrane-bounded structures (autophagic bodies) appear in the vacuole. Fusion provides an acidic environment and digestive function to the interior of the autophagosome.
|
SNAPIN,
SNAP29,
VCP,
CLN3,
TECPR1,
EPG5
|
GO:0097359
|
BP
|
UDP-glucosylation
|
The covalent attachment of a UDP-glucose residue to a substrate molecule.
|
UGGT1
|
GO:0097368
|
BP
|
establishment of Sertoli cell barrier
|
Establishment of a structure near the basement membrane in adjacent Sertoli cells of the seminiferous epithelium for maintaining spermatogenesis. The structure consists of tight junctions, basal ectoplasmic specializations, and desmosome-like junctions.
|
ICAM1,
ARID4B
|
GO:0097374
|
BP
|
sensory neuron axon guidance
|
The process in which the migration of an axon growth cone of a sensory neuron is directed to a specific target site in response to a combination of attractive and repulsive cues. A sensory neuron is an afferent neuron conveying sensory impulses.
|
NRP1
|
GO:0097403
|
BP
|
cellular response to raffinose
|
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a raffinose stimulus.
|
ZFP36L1
|
GO:0097411
|
BP
|
hypoxia-inducible factor-1alpha signaling pathway
|
A series of molecular signals mediated by hypoxia-inducible factor (HIF1) in response to lowered oxygen levels (hypoxia). Under hypoxic conditions, the oxygen-sensitive alpha-subunit of hypoxia-inducible factor (HIF)-1 dimerizes with a HIF1-beta subunit (also called ARNT or aryl-hydrocarbon-receptor nuclear translocator), translocates to the nucleus and activates transcription of genes whose products participate in responding to hypoxia.
|
CYBB,
PDK1,
HIF1A
|
GO:0097421
|
BP
|
liver regeneration
|
The regrowth of lost or destroyed liver.
|
EGFR,
TGFB1,
VTN,
TYMS,
HMOX1,
PCNA,
CEBPB,
IL10,
UCP2,
RPS16,
RAP1A,
RPL32,
HAMP,
RPL19,
SRSF1,
SRSF5,
RGN,
EZH2,
HFE,
SULF2,
CPB2
|
GO:0097428
|
BP
|
protein maturation by iron-sulfur cluster transfer
|
The transfer of an assembled iron-sulfur cluster from a scaffold protein to an acceptor protein that contributes to the attainment of the full functional capacity of a protein.
|
ISCA1
|
GO:0097435
|
BP
|
fibril organization
|
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of fibrils, insoluble fibrous aggregates consisting of polysaccharides and/or proteins.
|
HSP90AB1
|
GO:0097459
|
BP
|
iron ion import into cell
|
The directed movement of iron ions from outside of a cell into the cytoplasmic compartment. This may occur via transport across the plasma membrane or via endocytosis.
|
PICALM,
HFE
|
GO:0097460
|
BP
|
ferrous iron import into cell
|
The directed movement of ferrous iron (Fe(II) or Fe2+) ions from outside of a cell into the cytoplasmic compartment. This may occur via transport across the plasma membrane or via endocytosis.
|
TF,
TFR2
|
GO:0097461
|
BP
|
ferric iron import into cell
|
The directed movement of ferric iron (Fe(III) or Fe3+) ions from outside of a cell into the cytoplasmic compartment. This may occur via transport across the plasma membrane or via endocytosis.
|
STEAP4
|
GO:0097466
|
BP
|
glycoprotein ERAD pathway
|
An ERAD pathway whereby endoplasmic reticulum (ER)-resident glycoproteins are targeted for degradation. Includes differential processing of the glycoprotein sugar chains, retrotranslocation to the cytosol and degradation by the ubiquitin-proteasome pathway. A glycoprotein is a compound in which a carbohydrate component is covalently bound to a protein component.
|
EDEM1
|
GO:0097477
|
BP
|
lateral motor column neuron migration
|
The orderly movement of a lateral motor column neuron from one site to another. A lateral motor column neuron is a motor neuron that is generated only on limb levels and send axons into the limb mesenchyme.
|
DAB1
|
GO:0097484
|
BP
|
dendrite extension
|
Long distance growth of a single dendrite involved in cellular development.
|
STK11,
SLC9A6,
LLPH
|
GO:0097485
|
BP
|
neuron projection guidance
|
The process in which the migration of a neuron projection is directed to a specific target site in response to a combination of attractive and repulsive cues.
|
DPYSL4
|
GO:0097490
|
BP
|
sympathetic neuron projection extension
|
Long distance growth of a single sympathetic neuron projection involved in cellular development. A neuron projection is a prolongation or process extending from a nerve cell, e.g. an axon or dendrite.
|
NRP1,
NRP2,
SEMA3A
|
GO:0097491
|
BP
|
sympathetic neuron projection guidance
|
The process in which the migration of a sympathetic neuron projection is directed to a specific target site in response to a combination of attractive and repulsive cues.
|
NRP1,
NRP2,
SEMA3A
|
GO:0097494
|
BP
|
regulation of vesicle size
|
Any process that modulates the size of a vesicle.
|
RAB3B,
RAB22A
|
GO:0097497
|
BP
|
blood vessel endothelial cell delamination
|
The process of negative regulation of cell adhesion that results in blood vessel endothelial cells splitting off from an existing endothelial sheet.
|
TRPV4
|
GO:0097498
|
BP
|
endothelial tube lumen extension
|
Any endothelial tube morphogenesis process by which the tube is increased in length.
|
RHOA,
STARD13
|
GO:0097500
|
BP
|
receptor localization to nonmotile primary cilium
|
A process in which a receptor is transported to, or maintained in, a location within a nonmotile primary cilium.
|
BBIP1,
TULP3
|
GO:0097502
|
BP
|
mannosylation
|
The covalent attachment of a mannose residue to a substrate molecule.
|
ALG8,
ALG9
|
GO:0097503
|
BP
|
sialylation
|
The covalent attachment of sialic acid to a substrate molecule.
|
ST6GAL1,
ST8SIA6,
ST3GAL1,
ST3GAL3,
ST3GAL4,
ST3GAL2,
ST8SIA4,
ST6GAL2,
ST6GALNAC5,
ST6GALNAC4,
ST6GALNAC2,
ST3GAL6
|
GO:0097510
|
BP
|
base-excision repair, AP site formation via deaminated base removal
|
A base-excision repair, AP site formation process occurring via excision of a deaminated base.
|
UNG
|
GO:0097527
|
BP
|
necroptotic signaling pathway
|
A series of molecular signals which triggers the necroptotic death of a cell. The pathway starts with reception of a signal, is characterized by activation of receptor-interacting serine/threonine-protein kinase 1 and/or 3 (RIPK1/3, also called RIP1/3), and ends when the execution phase of necroptosis is triggered.
|
TLR3,
TNF,
FAS,
FADD,
RIPK1
|
GO:0097531
|
BP
|
mast cell migration
|
The movement of a mast cell within or between different tissues and organs of the body.
|
MITF,
STAT5B
|
GO:0097553
|
BP
|
calcium ion transmembrane import into cytosol
|
A process in which a calcium ion is transported from one side of a membrane to the other into the cytosol by means of some agent such as a transporter or pore.
|
ATP2B4
|
GO:0097581
|
BP
|
lamellipodium organization
|
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lamellipodium. A lamellipodium is a thin sheetlike process extended by the leading edge of a crawling fibroblast; contains a dense meshwork of actin filaments.
|
CTTN
|
GO:0097623
|
BP
|
potassium ion export across plasma membrane
|
The directed movement of potassium ions from inside of a cell, across the plasma membrane and into the extracellular region.
|
KCNH2
|
GO:0097638
|
BP
|
L-arginine import across plasma membrane
|
The directed movement of L-arginine from outside of a cell, across the plasma membrane and into the cytosol.
|
SLC7A2
|
GO:0097639
|
BP
|
L-lysine import across plasma membrane
|
The directed movement of L-lysine from outside of a cell, across the plasma membrane and into the cytosol.
|
SLC7A2
|
GO:0097640
|
BP
|
L-ornithine import across plasma membrane
|
The directed movement of L-ornithine from outside of a cell, across the plasma membrane and into the cytosol.
|
SLC7A2
|
GO:0097676
|
BP
|
histone H3-K36 dimethylation
|
The modification of histone H3 by addition of two methyl groups to lysine at position 36 of the histone.
|
ASH1L
|
GO:0097681
|
BP
|
double-strand break repair via alternative nonhomologous end joining
|
An instance of double-strand break repair via nonhomologous end joining that is independent of factors important for V(D)J recombination (as opposed to classical nonhomologous end joining). It often results in a deletion with microhomology (i.e. 5-25bp homology) at the repair junction. Among different subclasses of nonhomologous end joining (NHEJ), alternative NHEJ appears to play a significant role in the etiology of mutations that arise during cancer development and treatment.
|
POLQ,
PRKDC
|
GO:0098507
|
BP
|
polynucleotide 5' dephosphorylation
|
The process of removing one or more phosphate groups from the 5' end of a polynucleotide.
|
DUSP11
|
GO:0098532
|
BP
|
histone H3-K27 trimethylation
|
The modification of histone H3 by addition of three methyl groups to lysine at position 27 of the histone.
|
HIST1H1E,
HIST1H1C,
EZH2
|
GO:0098535
|
BP
|
de novo centriole assembly
|
Centriole assembly in which a centriole arises de novo by a process involving an electron dense structure known as a deuterosome, rather than by duplication of an existing centriole.
|
PLK4,
CEP152
|
GO:0098586
|
BP
|
cellular response to virus
|
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a virus.
|
PENK,
IL12A,
FMR1,
MAPK14,
TRIM6
|
GO:0098609
|
BP
|
cell-cell adhesion
|
The attachment of one cell to another cell via adhesion molecules.
|
ESYT2,
PDLIM1,
SDCBP,
NOP56,
DDX3X,
CCS,
PPL,
EXOC3,
FLNB,
IDH1,
RSL1D1,
CCNB2,
VAPB,
LYPLA2,
LDHA,
ALDOA,
KRT18,
ENO1,
ANXA2,
PFN1,
SLC3A2,
HSP90AB1,
HSPA1A,
HSPA1B,
HSPA5,
EEF2,
PKM,
RPS2,
EPCAM,
CAST,
PCMT1,
PAICS,
DNAJB1,
S100P,
EEF1D,
PRDX6,
YWHAB,
SFN,
S100A11,
RDX,
BSG,
TAGLN2,
CAPG,
EIF2S3,
TMPO,
TMPO,
EPS15,
RANBP1,
RANGAP1,
CRKL,
IQGAP1,
CAPZB,
RPL29,
CSNK1D,
RPL34,
FASN,
NUMB,
MRE11A,
EMD,
RPL14,
CCT8,
CAPZA1,
ARFIP1,
IST1,
RARS,
EIF5,
RPL15,
YWHAE,
RPL7A,
RPL23A,
RAB1A,
RPS26,
YWHAZ,
RACK1,
HIST1H3D,
RPL24,
HDLBP,
SPTBN1,
CALD1,
PRDX1,
TJP1,
GOLGA2,
AHNAK,
TWF1,
PAK2,
PICALM,
SNX1,
CKAP5,
CTTN,
TRIM25,
SEPT2,
STK38,
PCBP1,
CNN3,
MAPRE1,
RAB11B,
SEPT7,
PKN2,
DBN1,
FSCN1,
LRRFIP1,
COBLL1,
FNBP1L,
ARHGEF16,
TWF2,
LARP1,
MPRIP,
GIGYF2,
BZW1,
DHX29,
PHLDB2,
KTN1,
ERC1,
ABI1,
ARHGAP18,
SERBP1,
GPRC5A,
STXBP6,
KIAA1524,
ZC3H15,
PPP1R13L,
ATXN2L,
H1FX,
NDRG1,
GCN1,
EFHD2,
PERP,
PDLIM5,
SCYL1,
FMNL2,
FAM129B,
TMEM47,
CORO1B,
EHD4,
CHMP4B,
EPB41L1,
ADGRL3,
RTN4,
ANLN,
DIAPH3,
ARGLU1,
FLRT3,
VAPA,
TJP2,
TES,
LIMA1,
BAIAP2L1,
PUF60,
ASAP1,
MKL2,
MYO6,
MACF1,
RUVBL1,
SH3GLB1,
PPME1,
MMP24,
SNX9,
SNX5,
F11R,
STK24,
BZW2,
WASF2
|
GO:0098655
|
BP
|
cation transmembrane transport
|
A process in which a cation is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
|
SLC22A5,
CHRNB1,
CHRNA5,
CHRNA7,
ATP13A5,
FAM26F,
SLC30A9,
PIEZO1,
SLC41A3,
SLC41A2,
P2RX4,
ATP13A3,
CALHM2,
ATP13A2,
GAR1
|
GO:0098656
|
BP
|
anion transmembrane transport
|
A process in which an anion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
|
ABCC4,
ABCC5,
ABCA1,
ABCC1,
SLC4A8,
ABCC10,
LRRC8B,
LRRC8A,
LRRC8C,
SLC5A5,
SLC4A4
|
GO:0098700
|
BP
|
neurotransmitter loading into synaptic vesicle
|
The active transport of neurotransmitters into a synaptic vesicle. This import is fuelled by an electrochemical gradient across the vesicle membrane, established by the action proton pumps.
|
SLC18A2
|