GO:0072354

MF

histone kinase activity (H3-T3 specific)

Catalysis of the transfer of a phosphate group to the threonine-3 residue of the N-terminal tail of histone H3.

GSG2, VRK1

GO:0072518

MF

Rho-dependent protein serine/threonine kinase activity

Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. This reaction requires binding of the GTPase Rho.

ROCK2

GO:0072542

MF

protein phosphatase activator activity

Increases the activity of a protein phosphatase, an enzyme which catalyzes of the removal of a phosphate group from a protein substrate molecule.

CALM2

GO:0072572

MF

poly-ADP-D-ribose binding

Interacting selectively and non-covalently with polymeric ADP-D-ribose, a polymer that is composed of poly-ADP-D-ribose units linked through 1,2-glycosidic bonds at the ribose ring.

RNF146

GO:0072590

MF

N-acetyl-L-aspartate-L-glutamate ligase activity

Catalysis of the reaction: ATP + N-acetyl-L-aspartate + L-glutamate = ADP + phosphate + N-acetylaspartyl-glutamate.

RIMKLB

GO:0072591

MF

citrate-L-glutamate ligase activity

Catalysis of the reaction: ATP + citrate + L-glutamate = ADP + phosphate + beta-citryl-L-glutamate.

RIMKLB

GO:0080019

MF

fatty-acyl-CoA reductase (alcohol-forming) activity

Catalysis of the reaction: a very long chain fatty acyl-CoA + NADPH + H+ = a very long chain primary alcohol + NADP+ + CoA.

FAR2

GO:0080023

MF

3R-hydroxyacyl-CoA dehydratase activity

Catalysis of the reaction: 3R-hydroxyacyl-CoA = 2E-enoyl-CoA + H2O.

HACD1, HACD2

GO:0080025

MF

phosphatidylinositol-3,5-bisphosphate binding

Interacting selectively and non-covalently with phosphatidylinositol-3,5-bisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 3' and 5' positions.

SH3PXD2B, SNX3, WIPI1, COMMD1, GBF1, MAPKAP1, PLEKHA5, ATP13A2, WDR45, WIPI2

GO:0080101

MF

phosphatidyl-N-dimethylethanolamine N-methyltransferase activity

Catalysis of the reaction: S-adenosyl-L-methionine + phosphatidyl-N-dimethylethanolamine = S-adenosyl-L-homocysteine + phosphatidylcholine.

PEMT

GO:0080122

MF

AMP transmembrane transporter activity

Enables the transfer of AMP, adenosine monophosphate, from one side of a membrane to the other.

SLC25A17

GO:0080130

MF

L-phenylalanine:2-oxoglutarate aminotransferase activity

Catalysis of the reaction: L-phenylalanine + 2-oxoglutarate = phenylpyruvate + L-glutamate.

GOT2

GO:0080132

MF

fatty acid alpha-hydroxylase activity

Catalysis of the conversion of a fatty acid to an alpha-hydroxylated fatty acid. A hydroxyl group is added to the second carbon, counted from the carboxyl end, of a fatty acid chain.

FA2H

GO:0080146

MF

L-cysteine desulfhydrase activity

Catalysis of the reaction: L-cysteine + H2O = ammonia + pyruvate + hydrogen sulfide + H+.

CTH

GO:0086007

MF

voltage-gated calcium channel activity involved in cardiac muscle cell action potential

Enables the transmembrane transfer of a calcium ion by a voltage-gated channel across the plasma membrane of a cardiac muscle cell that contributes to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.

CACNA2D1, CACNA1C

GO:0086008

MF

voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization

Enables the transmembrane transfer of a potassium ion by a voltage-gated channel through the plasma membrane of a cardiac muscle cell contributing to the repolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.

KCNH2

GO:0086039

MF

calcium-transporting ATPase activity involved in regulation of cardiac muscle cell membrane potential

Catalysis of the transfer of a solute or solutes from one side of a cardiac muscle cell plasma membrane to the other according to the reaction: ATP + H2O + Ca2+(cis) = ADP + phosphate + Ca2+(trans). The transfer contributes to the regulation of the plasma membrane potential.

ATP2A2

GO:0086056

MF

voltage-gated calcium channel activity involved in AV node cell action potential

Enables the transmembrane transfer of a calcium ion by a voltage-gated channel across the plasma membrane of an AV node cardiac muscle cell that contributes to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.

CACNA1G, CACNA1C

GO:0086059

MF

voltage-gated calcium channel activity involved SA node cell action potential

Enables the transmembrane transfer of a calcium ion by a voltage-gated channel across the plasma membrane of an SA node cardiac muscle cell that contributes to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.

CACNA1G

GO:0086075

MF

gap junction channel activity involved in cardiac conduction electrical coupling

A wide pore channel activity that enables a direct cytoplasmic connection from one cardiomyocyte to an adjacent cardiomyocyte. The gap junction passes electrical signals between the cells contributing to cardiac conduction.

GJA1, GJA5

GO:0086077

MF

gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling

A wide pore channel activity that enables a direct cytoplasmic connection from an AV node cell to a bundle of His cell. The gap junction passes electrical signals between the cells contributing to cardiac conduction.

GJA5

GO:0086080

MF

protein binding involved in heterotypic cell-cell adhesion

Interacting selectively and non-covalently with any protein or protein complex contributing to the adhesion of two different types of cells.

GLDN, NRCAM

GO:0086083

MF

cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication

Interacting selectively and non-covalently with any protein or protein complex that results in the connection of a bundle of His cell with a Purkinje myocyte and contributes to the communication between the two cells.

JUP, DSP, DSC2, DSG2, PKP2

GO:0089720

MF

caspase binding

Interacting selectively and non-covalently with a caspase family protein.

NOL3, FADD

GO:0090450

MF

inosine-diphosphatase activity

Catalysis of the reaction: IDP + H2O = IMP + phosphate.

NUDT16

GO:0090541

MF

MIT domain binding

Interacting selectively and non-covalently with the MIT domain of a protein. The MIT domain is found in vacuolar sorting proteins, spastin (probable ATPase involved in the assembly or function of nuclear protein complexes), and a sorting nexin, which may play a role in intracellular trafficking.

IST1

GO:0090554

MF

phosphatidylcholine-translocating ATPase activity

Catalysis of the movement of phosphatidylcholine from one membrane bilayer leaflet to the other, driven by the hydrolysis of ATP.

ABCA1

GO:0090556

MF

phosphatidylserine-translocating ATPase activity

Catalysis of the movement of phosphatidylserine from one membrane bilayer leaflet to the other, driven by the hydrolysis of ATP.

ABCA1

GO:0090624

MF

endoribonuclease activity, cleaving miRNA-paired mRNA

Catalysis of the endonucleolytic cleavage of the mRNA in a double-stranded RNA molecule formed by the base pairing of an mRNA with an miRNA.

AGO2

GO:0097003

MF

adipokinetic hormone receptor activity

Combining with an adipokinetic hormone to initiate a change in cell activity. Adipokinetic hormones (AKHs) are peptide hormones that are involved in the mobilization of sugar and lipids from the insect fat body during energy-requiring activities such as flight and locomotion. They also contribute to hemolymph sugar homeostasis.

ADIPOR2, ADIPOR1

GO:0097016

MF

L27 domain binding

Interacting selectively and non-covalently with a L27 domain of a protein. L27 is composed of conserved negatively charged amino acids and a conserved aromatic amino acid. L27 domains can assemble proteins involved in signaling and establishment and maintenance of cell polarity into complexes by interacting in a heterodimeric manner.

DLG1, LIN7C

GO:0097020

MF

COPII adaptor activity

The binding activity of a molecule that brings together the COPII vesicle proteins and one or more other molecules, permitting them to function in a coordinated way.

TEX261

GO:0097027

MF

ubiquitin-protein transferase activator activity

Increases the activity of a ubiquitin-protein transferase, an enzyme that catalyzes the covalent attachment of ubiquitin to lysine in a substrate protein.

RING1, CDC20, FZR1

GO:0097100

MF

supercoiled DNA binding

Interacting selectively and non-covalently with supercoiled DNA. For example, during replication and transcription, template DNA is negatively supercoiled in the receding downstream DNA and positively supercoiled in the approaching downstream DNA.

PSIP1, HMGB1, HMGB2

GO:0097108

MF

hedgehog family protein binding

Interacting selectively and non-covalently with a member of the hedgehog protein family, signaling proteins involved in development.

PTCH1, HHIP

GO:0097109

MF

neuroligin family protein binding

Interacting selectively and non-covalently with a member of the neuroligin protein family, neuronal cell surface proteins that mediate synapse formation.

DLG4, NRXN1

GO:0097110

MF

scaffold protein binding

Interacting selectively and non-covalently with a scaffold protein. Scaffold proteins are crucial regulators of many key signaling pathways. Although not strictly defined in function, they are known to interact and/or bind with multiple members of a signaling pathway, tethering them into complexes.

MAP3K7, CACNA1G, KRT18, KRT8, VIM, DSP, GJA1, ATP2B4, MAPK3, NOS3, MAP2K2, CAV2, DLG4, MDM2, PDE4D, KCNH2, CASP8, NLGN4X, NLGN1, PANX1, TREM1, CRIPT

GO:0097153

MF

cysteine-type endopeptidase activity involved in apoptotic process

Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile, and contributing to the apoptotic process.

CASP9, CASP6, CASP8, PYCARD

GO:0097157

MF

pre-mRNA intronic binding

Interacting selectively and non-covalently with an intronic sequence of a pre-messenger RNA (pre-mRNA).

HNRNPL, HNRNPA2B1, SOX9, EP300, RNPC3, RBM4

GO:0097158

MF

pre-mRNA intronic pyrimidine-rich binding

Interacting selectively and non-covalently with a pyrimidine-rich (CU-rich) intronic sequence of a pre-messenger RNA (pre-mRNA).

RBM4

GO:0097159

MF

organic cyclic compound binding

Interacting selectively and non-covalently with an organic cyclic compound, any molecular entity that contains carbon arranged in a cyclic molecular structure.

MTNR1A

GO:0097161

MF

DH domain binding

Interacting selectively and non-covalently with a DH (Dbl homology) domain of a protein. The DH domain contains three structurally conserved regions separated by more variable regions. It is composed of 11 alpha helices that are folded into a flattened, elongated alpha-helix bundle in which two of the three conserved regions, conserved region 1 (CR1) and conserved region 3 (CR3), are exposed near the centre of one surface. CR1 and CR3, together with a part of alpha-6 and the DH/PH (pleckstrin homology) junction site, constitute the Rho GTPase interacting pocket.

EPHA4

GO:0097177

MF

mitochondrial ribosome binding

Interacting selectively and non-covalently with any part of a mitochondrial ribosome, a ribosome found in the mitochondrion of a eukaryotic cell.

C1QBP

GO:0097199

MF

cysteine-type endopeptidase activity involved in apoptotic signaling pathway

Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile, and contributing to the apoptotic signaling pathway.

CASP8

GO:0097200

MF

cysteine-type endopeptidase activity involved in execution phase of apoptosis

Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile, and contributing to the execution phase of apoptosis.

CFLAR

GO:0097260

MF

eoxin A4 synthase activity

Catalysis of the reaction: leukotriene A4 = eoxin A4.

ALOX15

GO:0097322

MF

7SK snRNA binding

Interacting selectively and non-covalently with a 7SK small nuclear RNA (7SK snRNA).

CCNT1, CCNT2, HEXIM1

GO:0097363

MF

protein O-GlcNAc transferase activity

Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + [protein]-L-serine = UDP + [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine, or UDP-N-acetyl-D-glucosamine + [protein]-L-threonine = UDP + [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine.

OGT, POMGNT2

GO:0097371

MF

MDM2/MDM4 family protein binding

Interacting selectively and non-covalently with any isoform of the MDM2/MDM4 protein family, comprising negative regulators of p53.

PSME3, PPARA, RFWD3

GO:0097383

MF

dIDP diphosphatase activity

Catalysis of the reaction: dIDP + H2O = dIMP + phosphate.

NUDT16

GO:0097493

MF

structural molecule activity conferring elasticity

The action of a molecule that contributes to the structural integrity of a complex or assembly within or outside a cell, providing elasticity and recoiling.

AHNAK, TTN

GO:0097573

MF

glutathione oxidoreductase activity

Catalysis of the reaction: protein-S-S-glutathione + glutathione-SH = protein-SH + glutathione-S-S-glutathione.

GLRX

GO:0097602

MF

cullin family protein binding

Interacting selectively and non-covalently with any member of the cullin family, hydrophobic proteins that act as scaffolds for ubiquitin ligases (E3).

PARK2, RBX1, SKP1, DCUN1D4, DCUN1D1

GO:0097603

MF

temperature-gated ion channel activity

Enables the transmembrane transfer of an ion by a channel that opens in response to a temperature stimulus (e.g. exposure to a temperature range different than the optimal temperature for that organism).

TRPV1

GO:0097626

MF

low-affinity L-arginine transmembrane transporter activity

Catalysis of the transfer of L-arginine from one side of a membrane to the other. In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations.

SLC7A2

GO:0097627

MF

high-affinity L-ornithine transmembrane transporter activity

Catalysis of the transfer of L-ornithine from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.

SLC7A2

GO:0097655

MF

serpin family protein binding

Interacting selectively and non-covalently with any member of the serpin protein family (serine protease inhibitors or classified inhibitor family I4). Serpins are a broadly distributed family of protease inhibitors that use a conformational change to inhibit target enzymes. They are central in controlling many important proteolytic cascades. The majority of serpins inhibit serine proteases, but serpins that inhibit caspases and papain-like cysteine proteases have also been identified. Rarely, serpins perform a non-inhibitory function; for example, several human serpins function as hormone transporters and certain serpins function as molecular chaperones or tumor suppressors.

CTSL

GO:0097677

MF

STAT family protein binding

Interacting selectively and non-covalently with any member of the signal transducers and activators of transcription (STAT) protein family. STATs are, as the name indicates, both signal transducers and transcription factors. STATs are activated by cytokines and some growth factors and thus control important biological processes including cell growth, cell differentiation, apoptosis and immune responses.

HSF1

GO:0097689

MF

iron channel activity

Enables the facilitated diffusion of an iron ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.

SLC40A1

GO:0098505

MF

G-rich strand telomeric DNA binding

Interacting selectively and non-covalently with G-rich, single-stranded, telomere-associated DNA.

HNRNPA1, TERF1, NABP2, POT1

GO:0098519

MF

nucleotide phosphatase activity, acting on free nucleotides

Catalysis of the reaction: nucleotide + H2O = nucleotide + phosphate.

DUSP11, NUDT16

GO:0098531

MF

transcription factor activity, direct ligand regulated sequence-specific DNA binding

A DNA binding transcription factor activity that is directly regulated by binding of a ligand to the protein with this activity. Examples include the lac and trp repressors in E.coli and many steroid hormone receptors.

RORA

GO:0098599

MF

palmitoyl hydrolase activity

Catalysis of a hydrolase reaction that removes a palmitoyl moiety from some substrate.

PPT2

GO:0098619

MF

selenocysteine-tRNA ligase activity

Catalysis of the reaction: tRNASec + L-Ser + ATP ---> Ser-tRNASec + AMP + Diphosphate.

SARS

GO:0098621

MF

phosphoseryl-selenocysteinyl-tRNA selenium transferase activity

Catalysis of the reaction: O-Phosphoseryl-tRNA(Sec) + Selenophosphoric acid + H2O => L-Selenocysteinyl-tRNA(Sec) + 2 phosphoric acid.

SEPSECS

GO:0098625

MF

methylselenol reductase activity

Catalysis of the reaction: NADPH + H+ + CH3SeOH => NADP+ + CH3SeH + H2O

TXNRD1

GO:0098626

MF

methylseleninic acid reductase activity

Catalysis of the reaction: NADPH + H+ + CH3SeO2H => NADP+ + CH3SeOH + H2O.

TXNRD1

GO:0098639

MF

collagen binding involved in cell-matrix adhesion

Any collagen binding that occurs as part of cell-matrix adhesion.

ITGA10, ITGB1, ITGA2, ITGA11

GO:0098641

MF

cadherin binding involved in cell-cell adhesion

Any cadherin binding that occurs as part of the process of cell-cell adhesion.

ESYT2, PDLIM1, CLIC1, SDCBP, NOP56, DDX3X, CCS, PPL, EXOC3, CTNND1, FLNB, IDH1, RSL1D1, CCNB2, VAPB, LYPLA2, LDHA, EGFR, ALDOA, ANXA1, ITGB1, KRT18, ENO1, ANXA2, PFN1, SLC3A2, HSP90AB1, HSPA1A, HSPA1B, HSPA5, EEF2, PKM, JUP, EZR, RPS2, EPCAM, CAST, FLNA, PCMT1, PAICS, ITGA6, DNAJB1, S100P, CTNNA2, EEF1D, PRDX6, YWHAB, SFN, S100A11, CTNNA1, CTNNB1, RDX, MYH9, BSG, TAGLN2, CAPG, EIF2S3, TMPO, TMPO, EPS15, RANBP1, RANGAP1, CRKL, IQGAP1, CAPZB, RPL29, CSNK1D, RPL34, FASN, NUMB, MRE11A, EMD, RPL14, CCT8, CAPZA1, ARFIP1, IST1, RARS, EIF5, RPL15, YWHAE, RPL7A, RPL23A, RAB1A, RPS26, YWHAZ, RACK1, HIST1H3D, RPL24, HDLBP, SPTBN1, CALD1, PRDX1, TJP1, GOLGA2, AHNAK, TWF1, DLG1, PAK2, PICALM, SNX1, CKAP5, CTTN, TRIM25, SEPT2, STK38, PCBP1, CNN3, MAPRE1, RAB11B, SEPT7, PKN2, DBN1, FSCN1, LRRFIP1, COBLL1, FNBP1L, ARHGEF16, TWF2, LARP1, MPRIP, GIGYF2, BZW1, DHX29, PHLDB2, KTN1, ERC1, ABI1, ARHGAP18, SERBP1, GPRC5A, STXBP6, KIAA1524, ZC3H15, PPP1R13L, ATXN2L, H1FX, NDRG1, GCN1, EFHD2, PDLIM5, SCYL1, FMNL2, FAM129B, PKP2, CORO1B, EHD4, CHMP4B, EPB41L1, RTN4, ANLN, DIAPH3, PARVA, ARGLU1, VAPA, TJP2, TES, LIMA1, BAIAP2L1, PUF60, ASAP1, MKL2, MYO6, MACF1, RUVBL1, SH3GLB1, PKP3, TLN1, PPME1, SNX9, SNX5, F11R, STK24, BZW2, WASF2

GO:0098770

MF

FBXO family protein binding

Interacting selectively and non-covalently with any member of the FBXO protein family. Members of this family have an F-box protein motif of approximately 50 amino acids that functions as a site of protein-protein interaction.

CDK6

GO:0098772

MF

molecular function regulator

A molecular function that modulates the activity of a gene product or complex. Examples include enzyme regulators and channel regulators.

SEC14L1

GO:0098821

MF

BMP receptor activity

Combining with a member of the bone morphogenetic protein (BMP) family, and transmitting a signal across the plasma membrane to initiate a change in cell activity.

ACVR2A, BMPR1A, BMPR2

GO:0098847

MF

sequence-specific single stranded DNA binding

Interacting selectively and non-covalently with single-stranded DNA of a specific nucleotide composition.

HSF1, PCBP1

GO:0101020

MF

estrogen 16-alpha-hydroxylase activity

Catalysis of the reaction: estrogen + donor-H2 + O2 = 16-alpha-hydroxyestrogen + H2O.

CYP1A1, CYP3A4, CYP3A5, CYP3A7

GO:0102007

MF

acyl-L-homoserine-lactone lactonohydrolase activity

Catalysis of the reaction: H2O + an N-acyl-L-homoserine lactone <=> H+ + an N-acyl-L-homoserine.

PON1

GO:0102132

MF

3-oxo-pimeloyl-[acp] methyl ester reductase activity

Catalysis of the reaction: NADP + a 3R-hydroxypimeloyl-[acp] methyl ester <=> NADPH + H+ + a 3-oxo-pimeloyl-[acp] methyl ester.

FASN

GO:0102336

MF

3-oxo-arachidoyl-CoA synthase activity

Catalysis of the reaction: stearoyl-CoA(4-) + malonyl-CoA(5-) + H+ <=> 3-oxoicosanoyl-CoA. + carbon dioxide + coenzyme A.

ELOVL7, ELOVL1, ELOVL4, ELOVL6, ELOVL5

GO:0102337

MF

3-oxo-cerotoyl-CoA synthase activity

Catalysis of the reaction: tetracosanoyl-CoA(4-) + malonyl-CoA(5-) + H+ <=> 3-oxohexacosanoyl-CoA + carbon dioxide + coenzyme A.

ELOVL7, ELOVL1, ELOVL4, ELOVL6, ELOVL5

GO:0102338

MF

3-oxo-lignoceronyl-CoA synthase activity

Catalysis of the reaction: behenoyl-CoA(4-) + malonyl-CoA(5-) + H+ <=> 3-oxotetracosanoyl-CoA. + carbon dioxide + coenzyme A.

ELOVL7, ELOVL1, ELOVL4, ELOVL6, ELOVL5

GO:0102339

MF

3-oxo-arachidoyl-CoA reductase activity

Catalysis of the reaction: (R)-3-hydroxyicosanoyl-CoA(4-) + NADP(3-) <=> 3-oxoicosanoyl-CoA + NADPH + H+.

HSD17B12

GO:0102340

MF

3-oxo-behenoyl-CoA reductase activity

Catalysis of the reaction: (R)-3-hydroxybehenoyl-CoA(4-) + NADP(3-) <=> 3-oxodocosanoyl-CoA + NADPH + H+.

HSD17B12

GO:0102341

MF

3-oxo-lignoceroyl-CoA reductase activity

Catalysis of the reaction: (R)-3-hydroxylignoceroyl-CoA + NADP <=> 3-oxotetracosanoyl-CoA + NADPH + H+.

HSD17B12

GO:0102344

MF

3-hydroxy-behenoyl-CoA dehydratase activity

Catalysis of the reaction: (R)-3-hydroxybehenoyl-CoA <=> trans-2-docosenoyl-CoA + H2O.

HACD1, HACD4, HACD2, HACD3

GO:0102345

MF

3-hydroxy-lignoceroyl-CoA dehydratase activity

Catalysis of the reaction: (R)-3-hydroxylignoceroyl-CoA(4-) <=> trans-2-tetracosenoyl-CoA + H2O.

HACD1, HACD4, HACD2, HACD3

GO:0102390

MF

mycophenolic acid acyl-glucuronide esterase activity

Catalysis of the reaction: mycophenolic acid O-acyl-glucuronide(1-) + H2O <=> mycophenolate + H+ + D-glucopyranuronate

ABHD10

GO:0102391

MF

decanoate--CoA ligase activity

Catalysis of the reaction: decanoate + ATP(4-) + coenzyme A(4-) <=> decanoyl-CoA(4-) + AMP(2-) + diphosphoric acid

SLC27A2, ACSL4, ACSL1, ACSL6

GO:1901611

MF

phosphatidylglycerol binding

Interacting selectively and non-covalently with phosphatidylglycerol.

PITPNA, PITPNC1

GO:1901612

MF

cardiolipin binding

Interacting selectively and non-covalently with cardiolipin.

ATP8B1, UQCC3

GO:1901640

MF

XTP binding

Interacting selectively and non-covalently with XTP.

NUDT16

GO:1901641

MF

ITP binding

Interacting selectively and non-covalently with ITP.

NUDT16

GO:1901707

MF

leptomycin B binding

Interacting selectively and non-covalently with leptomycin B.

ID3

GO:1901981

MF

phosphatidylinositol phosphate binding

Interacting selectively and non-covalently with phosphatidylinositol phosphate.

GAP43, PLCD1, FGD2, DENND1A, ANKFY1

GO:1902098

MF

calcitriol binding

Interacting selectively and non-covalently with calcitriol. Calcitriol (1,25-dihydroxycholecalciferol) is the hormonally active form of vitamin D3.

VDR

GO:1902118

MF

calcidiol binding

Interacting selectively and non-covalently with calcidiol.

GC

GO:1902121

MF

lithocholic acid binding

Interacting selectively and non-covalently with lithocholic acid.

VDR

GO:1902122

MF

chenodeoxycholic acid binding

Interacting selectively and non-covalently with chenodeoxycholic acid.

NR1H4

GO:1902282

MF

voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization

Enables the transmembrane transfer of a potassium ion by a voltage-gated channel through the plasma membrane of a ventricular cardiomyocyte contributing to the repolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.

KCNH2

GO:1902379

MF

chemoattractant activity involved in axon guidance

Any chemoattractant activity that is involved in axon guidance.

WNT5A

GO:1903135

MF

cupric ion binding

Interacting selectively and non-covalently with cupric ion, copper(2+).

ATP13A2

GO:1903763

MF

gap junction channel activity involved in cell communication by electrical coupling

Any gap junction channel activity that is involved in cell communication by electrical coupling.

GJA1