Search Geneontologies

Geneontologies

GO ID Ontology GO Term Term Definition Proteins

GO:1900226

BP

negative regulation of NLRP3 inflammasome complex assembly

Any process that stops, prevents or reduces the frequency, rate or extent of NLRP3 inflammasome complex assembly.

SIRT2

GO:1900227

BP

positive regulation of NLRP3 inflammasome complex assembly

Any process that activates or increases the frequency, rate or extent of NLRP3 inflammasome complex assembly.

TLR4, CD36

GO:1900235

BP

negative regulation of Kit signaling pathway

Any process that stops, prevents or reduces the frequency, rate or extent of Kit signaling pathway.

RABGEF1

GO:1900242

BP

regulation of synaptic vesicle endocytosis

Any process that modulates the frequency, rate or extent of synaptic vesicle endocytosis.

BTBD9

GO:1900243

BP

negative regulation of synaptic vesicle endocytosis

Any process that stops, prevents or reduces the frequency, rate or extent of synaptic vesicle endocytosis.

SYT11

GO:1900244

BP

positive regulation of synaptic vesicle endocytosis

Any process that activates or increases the frequency, rate or extent of synaptic vesicle endocytosis.

TOR1A, NLGN1

GO:1900246

BP

positive regulation of RIG-I signaling pathway

Any process that activates or increases the frequency, rate or extent of RIG-I signaling pathway.

PUM1, PUM2

GO:1900248

BP

negative regulation of cytoplasmic translational elongation

Any process that stops, prevents or reduces the frequency, rate or extent of cytoplasmic translational elongation.

CPEB2, CPEB3

GO:1900260

BP

negative regulation of RNA-directed RNA polymerase activity

Any process that stops, prevents or reduces the frequency, rate or extent of RNA-directed RNA polymerase activity.

EIF4A2

GO:1900264

BP

positive regulation of DNA-directed DNA polymerase activity

Any process that activates or increases the frequency, rate or extent of DNA-directed DNA polymerase activity.

RFC4, RFC2, RFC5, RFC3, CHTF18, DSCC1

GO:1900271

BP

regulation of long-term synaptic potentiation

Any process that modulates the frequency, rate or extent of long-term synaptic potentiation.

PAIP2

GO:1900273

BP

positive regulation of long-term synaptic potentiation

Any process that activates or increases the frequency, rate or extent of long-term synaptic potentiation.

STAU1, DRD2, CREB1, GRIN2A, EIF2AK4

GO:1900275

BP

negative regulation of phospholipase C activity

Any process that stops, prevents or reduces the frequency, rate or extent of phospholipase C activity.

BICD1

GO:1900276

BP

regulation of proteinase activated receptor activity

Any process that modulates the frequency, rate or extent of proteinase activated receptor activity.

BICD1

GO:1900281

BP

positive regulation of CD4-positive, alpha-beta T cell costimulation

Any process that activates or increases the frequency, rate or extent of CD4-positive, alpha-beta T cell costimulation.

TNFSF4

GO:1900363

BP

regulation of mRNA polyadenylation

Any process that modulates the frequency, rate or extent of mRNA polyadenylation.

SNRPA

GO:1900364

BP

negative regulation of mRNA polyadenylation

Any process that stops, prevents or reduces the frequency, rate or extent of mRNA polyadenylation.

SUPT5H, CCNT1, ZC3H14

GO:1900365

BP

positive regulation of mRNA polyadenylation

Any process that activates or increases the frequency, rate or extent of mRNA polyadenylation.

CPEB3

GO:1900387

BP

negative regulation of cell-cell adhesion by negative regulation of transcription from RNA polymerase II promoter

A negative regulation of transcription from RNA polymerase II promoter that results in negative regulation of cell-cell adhesion.

SNAI2

GO:1900407

BP

regulation of cellular response to oxidative stress

Any process that modulates the frequency, rate or extent of cellular response to oxidative stress.

PARK2, PINK1, FUT8

GO:1900424

BP

regulation of defense response to bacterium

Any process that modulates the frequency, rate or extent of defense response to bacterium.

SYT11, FOXP1

GO:1900425

BP

negative regulation of defense response to bacterium

Any process that stops, prevents or reduces the frequency, rate or extent of defense response to bacterium.

SIRT2

GO:1900453

BP

negative regulation of long term synaptic depression

Any process that stops, prevents or reduces the frequency, rate or extent of long term synaptic depression.

ADORA1, FMR1

GO:1900483

BP

regulation of protein targeting to vacuolar membrane

Any process that modulates the frequency, rate or extent of protein targeting to vacuolar membrane.

VAMP7

GO:1900535

BP

palmitic acid biosynthetic process

The chemical reactions and pathways resulting in the formation of palmitic acid.

ACOT7

GO:1900625

BP

positive regulation of monocyte aggregation

Any process that activates or increases the frequency, rate or extent of monocyte aggregation.

CD44, NR4A3, HAS2

GO:1900737

BP

negative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway

Any process that stops, prevents or reduces the frequency, rate or extent of phospholipase C-activating G-protein coupled receptor signaling pathway.

BICD1

GO:1900738

BP

positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway

Any process that activates or increases the frequency, rate or extent of phospholipase C-activating G-protein coupled receptor signaling pathway.

F2, GPR27

GO:1900740

BP

positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway

Any process that activates or increases the frequency, rate or extent of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway.

BCL2L11, TP53, BCL2, YWHAB, SFN, MAPK8, BID, YWHAE, YWHAZ, DYNLL1, E2F1, YWHAH, TP53BP2, PMAIP1, TFDP1, CASP8, BAD

GO:1900744

BP

regulation of p38MAPK cascade

Any process that modulates the frequency, rate or extent of p38MAPK cascade.

PER1, HGF, ULK4

GO:1900745

BP

positive regulation of p38MAPK cascade

Any process that activates or increases the frequency, rate or extent of p38MAPK cascade.

GADD45B, GADD45G, BMP2, VEGFA, GADD45A, LEP, XDH, MAP3K5, PRMT1, MAP3K4

GO:1900747

BP

negative regulation of vascular endothelial growth factor signaling pathway

Any process that stops, prevents or reduces the frequency, rate or extent of vascular endothelial growth factor signaling pathway.

DCN, XDH

GO:1900748

BP

positive regulation of vascular endothelial growth factor signaling pathway

Any process that activates or increases the frequency, rate or extent of vascular endothelial growth factor signaling pathway.

MYO1C, CCBE1

GO:1900825

BP

regulation of membrane depolarization during cardiac muscle cell action potential

Any process that modulates the frequency, rate or extent of membrane depolarization during a cardiac muscle cell action potential.

GJA5, RANGRF

GO:1900827

BP

positive regulation of membrane depolarization during cardiac muscle cell action potential

Any process that activates or increases the frequency, rate or extent of membrane depolarization during a cardiac muscle cell action potential.

ANK3

GO:1901003

BP

negative regulation of fermentation

Any process that stops, prevents or reduces the frequency, rate or extent of fermentation.

PRKCDBP

GO:1901016

BP

regulation of potassium ion transmembrane transporter activity

Any process that modulates the frequency, rate or extent of potassium ion transmembrane transporter activity.

WWP2, YWHAE, FHL1, NEDD4L

GO:1901017

BP

negative regulation of potassium ion transmembrane transporter activity

Any process that stops, prevents or reduces the frequency, rate or extent of potassium ion transmembrane transporter activity.

ACTN2, NEDD4L, CAB39

GO:1901018

BP

positive regulation of potassium ion transmembrane transporter activity

Any process that activates or increases the frequency, rate or extent of potassium ion transmembrane transporter activity.

ATP1B1, ACTN2, ATP1B3, ANK2

GO:1901019

BP

regulation of calcium ion transmembrane transporter activity

Any process that modulates the frequency, rate or extent of calcium ion transmembrane transporter activity.

ANK2

GO:1901020

BP

negative regulation of calcium ion transmembrane transporter activity

Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion transmembrane transporter activity.

PLN

GO:1901021

BP

positive regulation of calcium ion transmembrane transporter activity

Any process that activates or increases the frequency, rate or extent of calcium ion transmembrane transporter activity.

ANK2

GO:1901026

BP

ripoptosome assembly involved in necroptotic process

The aggregation, arrangement and bonding together of ripoptosome components leading to a necroptotic process.

RIPK1, SIRT2

GO:1901029

BP

negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway

Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway.

SLC25A5, HSPA1A, HSPA1B

GO:1901030

BP

positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway

Any process that activates or increases the frequency, rate or extent of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway.

ZNF205, GSK3B, BID, BAX

GO:1901031

BP

regulation of response to reactive oxygen species

Any process that modulates the frequency, rate or extent of response to reactive oxygen species.

SESN2, SESN3, SESN1

GO:1901074

BP

regulation of engulfment of apoptotic cell

Any process that modulates the frequency, rate or extent of engulfment of apoptotic cell.

ALOX15

GO:1901077

BP

regulation of relaxation of muscle

Any process that modulates the frequency, rate or extent of relaxation of muscle.

SRI

GO:1901094

BP

negative regulation of protein homotetramerization

Any process that stops, prevents or reduces the frequency, rate or extent of protein homotetramerization.

PEX14

GO:1901097

BP

negative regulation of autophagosome maturation

Any process that stops, prevents or reduces the frequency, rate or extent of autophagosome maturation.

UBQLN4

GO:1901098

BP

positive regulation of autophagosome maturation

Any process that activates or increases the frequency, rate or extent of autophagosome maturation.

ADRB2, CALCOCO2

GO:1901142

BP

insulin metabolic process

The chemical reactions and pathways involving insulin.

ERN1, IDE

GO:1901143

BP

insulin catabolic process

The chemical reactions and pathways resulting in the breakdown of insulin.

IDE

GO:1901164

BP

negative regulation of trophoblast cell migration

Any process that stops, prevents or reduces the frequency, rate or extent of trophoblast cell migration.

TIMP1, ARHGDIB

GO:1901165

BP

positive regulation of trophoblast cell migration

Any process that activates or increases the frequency, rate or extent of trophoblast cell migration.

ACVR1B, C1QBP, SMURF2

GO:1901166

BP

neural crest cell migration involved in autonomic nervous system development

Any neural crest cell migration that is involved in autonomic nervous system development.

NRP1, SEMA3A

GO:1901184

BP

regulation of ERBB signaling pathway

Any process that modulates the frequency, rate or extent of ERBB signaling pathway.

SH3TC2

GO:1901187

BP

regulation of ephrin receptor signaling pathway

Any process that modulates the frequency, rate or extent of ephrin receptor signaling pathway.

ANKS1A

GO:1901194

BP

negative regulation of formation of translation preinitiation complex

Any process that stops, prevents or reduces the frequency, rate or extent of formation of translation preinitiation complex.

RPL13A

GO:1901201

BP

regulation of extracellular matrix assembly

Any process that modulates the frequency, rate or extent of extracellular matrix assembly.

AGT, NOTCH1

GO:1901203

BP

positive regulation of extracellular matrix assembly

Any process that activates or increases the frequency, rate or extent of extracellular matrix assembly.

TGFB1, SOX9, SMAD3, RGCC

GO:1901205

BP

negative regulation of adrenergic receptor signaling pathway involved in heart process

Any process that stops, prevents or reduces the frequency, rate or extent of a cardiac adrenergic receptor signaling pathway.

ATP2B4

GO:1901214

BP

regulation of neuron death

Any process that modulates the frequency, rate or extent of neuron death.

RAB29, CLU, CCL5, EPHB1, RRAS2, DHCR24, SARM1, CHP1, TBK1

GO:1901215

BP

negative regulation of neuron death

Any process that stops, prevents or reduces the frequency, rate or extent of neuron death.

PARK2, APOE, IL6, CREB1, AKT1, CTNNB1, SERPINF1, SNCA, STAT3, PSMC1, CDK5, HSF1, REL, PPARA, TMEM259, SORL1, CHMP4B, ATP13A2, PPARGC1A

GO:1901216

BP

positive regulation of neuron death

Any process that activates or increases the frequency, rate or extent of neuron death.

EIF2S1, PARP1, CLU, ELK1, GSK3B, PICALM, TP53BP2, BAD, MAP3K5, DDIT4

GO:1901222

BP

regulation of NIK/NF-kappaB signaling

Any process that modulates the frequency, rate or extent of NIK/NF-kappaB signaling.

UACA, AKIP1, PTPN22

GO:1901223

BP

negative regulation of NIK/NF-kappaB signaling

Any process that stops, prevents or reduces the frequency, rate or extent of NIK/NF-kappaB signaling.

TSPAN6, RELA, HDAC7, ADIPOR1

GO:1901224

BP

positive regulation of NIK/NF-kappaB signaling

Any process that activates or increases the frequency, rate or extent of NIK/NF-kappaB signaling.

ACTN4, TNF, CALR, RC3H2

GO:1901253

BP

negative regulation of intracellular transport of viral material

Any process that stops, prevents or reduces the frequency, rate or extent of intracellular transport of viral material.

BST2

GO:1901254

BP

positive regulation of intracellular transport of viral material

Any process that activates or increases the frequency, rate or extent of intracellular transport of viral material.

FMR1

GO:1901255

BP

nucleotide-excision repair involved in interstrand cross-link repair

Any nucleotide-excision repair that is involved in interstrand cross-link repair.

XPA, ERCC4

GO:1901256

BP

regulation of macrophage colony-stimulating factor production

Any process that modulates the frequency, rate or extent of macrophage colony-stimulating factor production.

FOXP1

GO:1901264

BP

carbohydrate derivative transport

The directed movement of a carbohydrate derivative into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

SLC35E3

GO:1901292

BP

nucleoside phosphate catabolic process

The chemical reactions and pathways resulting in the breakdown of a nucleoside phosphate.

NUDT15

GO:1901296

BP

negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment

Any process that stops, prevents or reduces the frequency, rate or extent of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment.

DKK1

GO:1901299

BP

negative regulation of hydrogen peroxide-mediated programmed cell death

Any process that stops, prevents or reduces the frequency, rate or extent of hydrogen peroxide-mediated programmed cell death.

MET, HGF

GO:1901300

BP

positive regulation of hydrogen peroxide-mediated programmed cell death

Any process that activates or increases the frequency, rate or extent of hydrogen peroxide-mediated programmed cell death.

FOXO3, PAWR, HDAC6

GO:1901303

BP

negative regulation of cargo loading into COPII-coated vesicle

Any process that stops, prevents or reduces the frequency, rate or extent of cargo loading into a COPII-coated vesicle.

INSIG1

GO:1901315

BP

negative regulation of histone H2A K63-linked ubiquitination

Any process that stops, prevents or reduces the frequency, rate or extent of histone H2A K63-linked ubiquitination.

UBR5, OTUB1

GO:1901318

BP

negative regulation of flagellated sperm motility

Any process that stops, prevents or reduces the frequency, rate or extent of flagellated sperm motility.

RGN

GO:1901350

BP

cell-cell signaling involved in cell-cell junction organization

Any cell-cell signaling that is involved in cell-cell junction organization.

TJP1

GO:1901355

BP

response to rapamycin

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a rapamycin stimulus.

HNRNPD

GO:1901373

BP

lipid hydroperoxide transport

The directed movement of a lipid hydroperoxide into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

SCP2

GO:1901374

BP

acetate ester transport

The directed movement of an acetate ester into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

SLC22A1

GO:1901379

BP

regulation of potassium ion transmembrane transport

Any process that modulates the frequency, rate or extent of potassium ion transmembrane transport.

PRNP, DPP6, KCNH2, KCNIP2

GO:1901380

BP

negative regulation of potassium ion transmembrane transport

Any process that stops, prevents or reduces the frequency, rate or extent of potassium ion transmembrane transport.

CAV1, KCNH2, NEDD4L, CAB39

GO:1901381

BP

positive regulation of potassium ion transmembrane transport

Any process that activates or increases the frequency, rate or extent of potassium ion transmembrane transport.

KCNH2, AKAP6

GO:1901382

BP

regulation of chorionic trophoblast cell proliferation

Any process that modulates the frequency, rate or extent of chorionic trophoblast cell proliferation.

BOK

GO:1901385

BP

regulation of voltage-gated calcium channel activity

Any process that modulates the frequency, rate or extent of voltage-gated calcium channel activity.

DMD, CACNB3, AHNAK, STAC

GO:1901386

BP

negative regulation of voltage-gated calcium channel activity

Any process that stops, prevents or reduces the frequency, rate or extent of voltage-gated calcium channel activity.

DRD2, OPRL1, FMR1

GO:1901387

BP

positive regulation of voltage-gated calcium channel activity

Any process that activates or increases the frequency, rate or extent of voltage-gated calcium channel activity.

EHD3

GO:1901407

BP

regulation of phosphorylation of RNA polymerase II C-terminal domain

Any process that modulates the frequency, rate or extent of phosphorylation of RNA polymerase II C-terminal domain.

BRD4

GO:1901409

BP

positive regulation of phosphorylation of RNA polymerase II C-terminal domain

Any process that activates or increases the frequency, rate or extent of phosphorylation of RNA polymerase II C-terminal domain.

CCNT1, CCNT2, CCNL2, CCNL1

GO:1901475

BP

pyruvate transmembrane transport

The directed movement of pyruvate across a membrane.

SLC16A7

GO:1901491

BP

negative regulation of lymphangiogenesis

Any process that stops, prevents or reduces the frequency, rate or extent of lymphangiogenesis.

FOXC1

GO:1901492

BP

positive regulation of lymphangiogenesis

Any process that activates or increases the frequency, rate or extent of lymphangiogenesis.

VEGFC, CCBE1

GO:1901509

BP

regulation of endothelial tube morphogenesis

Any process that modulates the frequency, rate or extent of endothelial tube morphogenesis.

ADAMTS12, FOXP1

GO:1901522

BP

positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus

Any positive regulation of transcription from RNA polymerase II promoter that is involved in cellular response to chemical stimulus.

SMAD9, BMP2, DLX5, SMAD4, RUNX2, SMAD1, SMAD5

GO:1901529

BP

positive regulation of anion channel activity

Any process that activates or increases the frequency, rate or extent of anion channel activity.

TCAF1

GO:1901532

BP

regulation of hematopoietic progenitor cell differentiation

Any process that modulates the frequency, rate or extent of hematopoietic progenitor cell differentiation.

PDCD2