GO ID |
Ontology |
GO Term |
Term Definition |
Proteins |
GO:0090271
|
BP
|
positive regulation of fibroblast growth factor production
|
Any process that increases the rate, frequency or extent of the appearance of a fibroblast growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
|
PTGS2,
HEG1
|
GO:0090272
|
BP
|
negative regulation of fibroblast growth factor production
|
Any process that decreases the rate, frequency or extent of the appearance of a fibroblast growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
|
FGFR1,
RGCC
|
GO:0090274
|
BP
|
positive regulation of somatostatin secretion
|
Any process that increases the rate, frequency, extent of the regulated release of somatostatin from secretory granules in the D cells of the pancreas.
|
SCT
|
GO:0090277
|
BP
|
positive regulation of peptide hormone secretion
|
Any process that increases the rate, frequency, or extent of the regulated release of a peptide hormone from secretory granules.
|
INS,
FGA,
FGB,
FGG,
HFE,
RASL10B,
TFR2
|
GO:0090279
|
BP
|
regulation of calcium ion import
|
Any process that modulates the rate, frequency, or extent of the directed movement of calcium ions into a cell or organelle.
|
CTNNB1,
PKD2,
HOMER1,
WNK3
|
GO:0090280
|
BP
|
positive regulation of calcium ion import
|
Any process that increases the rate, frequency, or extent of the directed movement of calcium ions into a cell or organelle.
|
CASK,
GRM6,
PDGFB,
GCG,
PDGFRB,
CCL3,
CCL2,
LGALS3,
ZP3,
CXCL12,
STC1,
TRPV2
|
GO:0090281
|
BP
|
negative regulation of calcium ion import
|
Any process that decreases the rate, frequency, or extent of the directed movement of calcium ions into a cell or organelle.
|
SPINK1,
PLN,
SLC30A1
|
GO:0090285
|
BP
|
negative regulation of protein glycosylation in Golgi
|
Any process that decreases the rate, frequency, or extent of the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid in any compartment of the Golgi apparatus.
|
TMEM59
|
GO:0090286
|
BP
|
cytoskeletal anchoring at nuclear membrane
|
The process in which cytoskeletal filaments are directly or indirectly linked to the nuclear membrane.
|
SYNE2,
SPAG4,
SUN2
|
GO:0090287
|
BP
|
regulation of cellular response to growth factor stimulus
|
Any process that modulates the rate, frequency, or extent of a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth factor stimulus.
|
FBN1,
FBN2,
FBN3
|
GO:0090288
|
BP
|
negative regulation of cellular response to growth factor stimulus
|
Any process that decreases the rate, frequency, or extent of a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth factor stimulus.
|
CASK,
SLIT2
|
GO:0090290
|
BP
|
positive regulation of osteoclast proliferation
|
Any process that increases the rate, frequency, or extent of the multiplication or reproduction of osteoclasts, resulting in the expansion of an osteoclast cell population.
|
PTH
|
GO:0090291
|
BP
|
negative regulation of osteoclast proliferation
|
Any process that decreases the rate, frequency, or extent of the multiplication or reproduction of osteoclasts, resulting in the expansion of an osteoclast cell population.
|
GREM1,
TNFAIP3
|
GO:0090292
|
BP
|
nuclear matrix anchoring at nuclear membrane
|
The process in which the nuclear matrix, the dense fibrillar network lying on the inner side of the nuclear membrane, is directly or indirectly linked to the nuclear membrane.
|
SUN2
|
GO:0090298
|
BP
|
negative regulation of mitochondrial DNA replication
|
Any process that decreases the rate, frequency or extent of the process in which new strands of DNA are synthesized in the mitochondrion.
|
PID1
|
GO:0090303
|
BP
|
positive regulation of wound healing
|
Any process that increases the rate, frequency, or extent of the series of events that restore integrity to a damaged tissue, following an injury.
|
VTN,
ANXA1,
INSL3,
KANK1,
MYLK,
HBEGF
|
GO:0090305
|
BP
|
nucleic acid phosphodiester bond hydrolysis
|
The nucleic acid metabolic process in which the phosphodiester bonds between nucleotides are cleaved by hydrolysis.
|
ZC3H12D,
EME2,
ENPP3,
RAD1,
REV3L,
DXO,
TDP2,
POLA1,
RAG1,
ENPP1,
MRE11A,
DNA2,
POLG,
POLE,
G3BP1,
ENPP2,
TSN,
TATDN3,
ZC3H12B,
TATDN1,
RAD9B,
PGAP1,
FANCM,
XRN1,
REXO1,
RAD50,
EME1,
DCLRE1C,
RAD9A,
TREX2,
MGME1,
PELO,
ZC3H12C,
TDP1,
EXOG
|
GO:0090306
|
BP
|
spindle assembly involved in meiosis
|
The aggregation, arrangement and bonding together of a set of components to form the spindle that contributes to the process of meiosis.
|
GOLGA2,
ASPM
|
GO:0090307
|
BP
|
mitotic spindle assembly
|
The aggregation, arrangement and bonding together of a set of components to form the spindle that contributes to the process of mitosis.
|
ARHGEF10,
BIRC5,
ZNF207,
MYBL2,
FLNA,
NEK2,
KIF11,
RHOA,
RAB11A,
GOLGA2,
MZT1,
KPNB1,
FAM175B,
MAP9,
PIBF1,
TUBGCP3,
KIFC1,
WRAP73,
TPX2
|
GO:0090308
|
BP
|
regulation of methylation-dependent chromatin silencing
|
Any process that modulates the rate, frequency, or extent of the repression of transcription by methylation of DNA, leading to the formation of heterochromatin.
|
UHRF2,
UHRF1
|
GO:0090309
|
BP
|
positive regulation of methylation-dependent chromatin silencing
|
Any process that increases the rate, frequency, or extent of the repression of transcription by methylation of DNA, leading to the formation of heterochromatin.
|
DNMT1,
TRIM28
|
GO:0090311
|
BP
|
regulation of protein deacetylation
|
Any process that modulates the rate, frequency, or extent of protein deacetylation, the removal of an acetyl group from a protein amino acid. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid.
|
SPRED1,
CCAR2
|
GO:0090314
|
BP
|
positive regulation of protein targeting to membrane
|
Any process that increases the frequency, rate or extent of the process of directing proteins towards a membrane, usually using signals contained within the protein.
|
MYO1C,
ITGB1BP1,
ERBB2,
CCL2,
STOM,
AKT2,
CDK5,
ANK3,
C2CD5,
CEMIP,
MIEF2,
CHP1,
CIB1,
MFF,
TCAF1
|
GO:0090315
|
BP
|
negative regulation of protein targeting to membrane
|
Any process that decreases the frequency, rate or extent of the process of directing proteins towards a membrane, usually using signals contained within the protein.
|
ITGB1BP1,
GDI1,
INPP5K
|
GO:0090316
|
BP
|
positive regulation of intracellular protein transport
|
Any process that activates or increases the frequency, rate or extent of the directed movement of proteins within cells.
|
RAB29,
OAZ2,
PCNT,
TPR,
OAZ1,
CDC42,
VAMP2,
PCM1,
RUFY3,
KIF20B,
RBM22
|
GO:0090317
|
BP
|
negative regulation of intracellular protein transport
|
Any process that decreases the frequency, rate or extent of the directed movement of proteins within cells.
|
ADIPOQ
|
GO:0090324
|
BP
|
negative regulation of oxidative phosphorylation
|
Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the phosphorylation of ADP to ATP that accompanies the oxidation of a metabolite through the operation of the respiratory chain. Oxidation of compounds establishes a proton gradient across the membrane, providing the energy for ATP synthesis.
|
PPIF
|
GO:0090325
|
BP
|
regulation of locomotion involved in locomotory behavior
|
Any process that modulates the frequency, rate, or extent of the self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement.
|
DRD2
|
GO:0090327
|
BP
|
negative regulation of locomotion involved in locomotory behavior
|
Any process that decreases the frequency, rate, or extent of the self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement.
|
ARRDC3
|
GO:0090330
|
BP
|
regulation of platelet aggregation
|
Any process that modulates the rate, frequency or extent of platelet aggregation. Platelet aggregation is the adhesion of one platelet to one or more other platelets via adhesion molecules.
|
LYN,
PRKCA,
SYK,
PRKCQ
|
GO:0090331
|
BP
|
negative regulation of platelet aggregation
|
Any process that decreases the rate, frequency or extent of platelet aggregation. Platelet aggregation is the adhesion of one platelet to one or more other platelets via adhesion molecules.
|
SERPINE2,
ABAT,
PRKCD,
ADAMTS18,
UBASH3B,
C1QTNF1
|
GO:0090335
|
BP
|
regulation of brown fat cell differentiation
|
Any process that modulates the rate, frequency, or extent of brown fat cell differentiation. Brown fat cell differentiation is the process in which a relatively unspecialized cell acquires specialized features of a brown adipocyte, an animal connective tissue cell involved in adaptive thermogenesis. Brown adipocytes contain multiple small droplets of triglycerides and a high number of mitochondria.
|
LEP,
FTO,
DUSP10
|
GO:0090336
|
BP
|
positive regulation of brown fat cell differentiation
|
Any process that increases the rate, frequency, or extent of brown fat cell differentiation. Brown fat cell differentiation is the process in which a relatively unspecialized cell acquires specialized features of a brown adipocyte, an animal connective tissue cell involved in adaptive thermogenesis. Brown adipocytes contain multiple small droplets of triglycerides and a high number of mitochondria.
|
INS,
PTGS2,
MAPK14
|
GO:0090340
|
BP
|
positive regulation of secretion of lysosomal enzymes
|
Any process that increases the rate, frequency or extent of secretion of lysosomal enzymes, the controlled release of lysosomal enzymes by a cell.
|
NR1H2
|
GO:0090341
|
BP
|
negative regulation of secretion of lysosomal enzymes
|
Any process that decreases the rate, frequency or extent of secretion of lysosomal enzymes, the controlled release of lysosomal enzymes by a cell.
|
NR1H3
|
GO:0090343
|
BP
|
positive regulation of cell aging
|
Any process that increases the rate, frequency, or extent of cell aging. Cell aging is the progression of the cell from its inception to the end of its lifespan.
|
LMNA
|
GO:0090344
|
BP
|
negative regulation of cell aging
|
Any process that decreases the rate, frequency, or extent of cell aging. Cell aging is the progression of the cell from its inception to the end of its lifespan.
|
MIF,
PTEN,
FOXM1,
FZR1
|
GO:0090350
|
BP
|
negative regulation of cellular organofluorine metabolic process
|
Any process that decreases the rate, frequency or extent of the chemical reactions and pathways involving organofluorine compounds, as carried out by individual cells.
|
CYP2D6
|
GO:0090361
|
BP
|
regulation of platelet-derived growth factor production
|
Any process that modulates the rate, frequency, or extent of the appearance of any platelet-derived growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
|
NDRG2
|
GO:0090362
|
BP
|
positive regulation of platelet-derived growth factor production
|
Any process that increases the rate, frequency, or extent of the appearance of any platelet-derived growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
|
PTGS2
|
GO:0090370
|
BP
|
negative regulation of cholesterol efflux
|
Any process that decreases the frequency, rate or extent of cholesterol efflux. Cholesterol efflux is the directed movement of cholesterol, cholest-5-en-3-beta-ol, out of a cell or organelle.
|
SREBF2
|
GO:0090382
|
BP
|
phagosome maturation
|
A process that is carried out at the cellular level which results in the arrangement of constituent parts of a phagosome within a cell. Phagosome maturation begins with endocytosis and formation of the early phagosome and ends with the formation of the hybrid organelle, the phagolysosome.
|
RAB7A,
RAB31,
RAB32,
RAB34
|
GO:0090383
|
BP
|
phagosome acidification
|
Any process that reduces the pH of the phagosome, measured by the concentration of the hydrogen ion.
|
ATP6V0E1,
ATP6V1G1,
ATP6V1G2,
ATP6V1B2,
ATP6V1C1,
RAB7A,
ATP6V0D1,
TCIRG1,
ATP6V1F,
ATP6V1C2,
ATP6V0A1,
ATP6V1H,
ATP6V1D
|
GO:0090385
|
BP
|
phagosome-lysosome fusion
|
The creation of a phagolysosome from a phagosome and a lysosome.
|
RAB7A,
RAB34
|
GO:0090394
|
BP
|
negative regulation of excitatory postsynaptic potential
|
Any process that prevents the establishment or decreases the extent of the excitatory postsynaptic potential (EPSP) which is a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential.
|
NPY2R,
PTEN,
MTMR2,
NLGN4X
|
GO:0090398
|
BP
|
cellular senescence
|
A cell aging process stimulated in response to cellular stress, whereby normal cells lose the ability to divide through irreversible cell cycle arrest.
|
OPA1,
H2AFX,
CALR,
CDKN1A,
ID2,
MAP2K1,
PRKCD,
SMC5,
KAT6A,
PRMT6,
SMC6
|
GO:0090399
|
BP
|
replicative senescence
|
A cell aging process associated with the dismantling of a cell as a response to telomere shortening and/or cellular aging.
|
CHEK1,
TP53,
MME,
CDKN1A
|
GO:0090400
|
BP
|
stress-induced premature senescence
|
A cellular senescence process associated with the dismantling of a cell as a response to environmental factors such as hydrogen peroxide or X-rays.
|
CDKN1A,
MAPK14
|
GO:0090402
|
BP
|
oncogene-induced cell senescence
|
A cellular senescence process associated with the dismantling of a cell as a response to oncogenic stress, such as the activation of the Ras oncogenic family.
|
HMGA1,
HMGA2
|
GO:0090403
|
BP
|
oxidative stress-induced premature senescence
|
A cellular senescence process associated with the dismantling of a cell as a response to oxidative stress, e.g. high levels of reactive oxygen species, such as superoxide anions, hydrogen peroxide, and hydroxyl radicals.
|
ARNTL,
TP53
|
GO:0090425
|
BP
|
acinar cell differentiation
|
The epithelial cell differentiation process in which a relatively unspecialized cell acquires specialized features of an acinar cell, a secretory cell that is grouped together with other cells of the same type to form grape-shaped clusters known as acini.
|
PROX1
|
GO:0090481
|
BP
|
pyrimidine nucleotide-sugar transmembrane transport
|
The directed movement of pyrimidine nucleotide-sugars across a membrane. Pyrimidine nucleotide-sugars are pyrimidine nucleotides in glycosidic linkage with a monosaccharide or monosaccharide derivative.
|
SLC35D2,
SLC35D1
|
GO:0090500
|
BP
|
endocardial cushion to mesenchymal transition
|
A transition where an endocardial cushion cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.
|
HAS2
|
GO:0090501
|
BP
|
RNA phosphodiester bond hydrolysis
|
The RNA metabolic process in which the phosphodiester bonds between ribonucleotides are cleaved by hydrolysis.
|
ANG,
AZGP1,
SMG5
|
GO:0090502
|
BP
|
RNA phosphodiester bond hydrolysis, endonucleolytic
|
The chemical reactions and pathways involving the hydrolysis of internal 3',5'-phosphodiester bonds in one or two strands of ribonucleotides.
|
RNASET2,
KIAA0391,
ERN1,
RNASEH2A,
POP7,
RPP40,
POP4,
RNASE1,
RNASE2,
RNASE4,
FEN1,
HRSP12,
RPP30,
RNASEL,
LACTB2,
RNASEH2B,
RNASEK,
ZC3H3,
TSEN15,
POP5,
EDC3,
RPP25,
MRPL44,
AGO2,
NOB1,
DICER1,
EXO1
|
GO:0090503
|
BP
|
RNA phosphodiester bond hydrolysis, exonucleolytic
|
The chemical reactions and pathways involving the hydrolysis of terminal 3',5'-phosphodiester bonds in one or two strands of ribonucleotides.
|
CNOT1,
PARN,
PAN3,
DCP2,
PNPT1,
ISG20,
EXOSC4,
CNOT7,
NOCT,
CNOT6,
DIS3,
REXO2
|
GO:0090521
|
BP
|
glomerular visceral epithelial cell migration
|
The orderly movement of a podocyte from one site to another, often during the development of a multicellular organism or multicellular structure. A podocyte is a specialized kidney epithelial cell.
|
NUP93,
ANLN
|
GO:0090526
|
BP
|
regulation of gluconeogenesis involved in cellular glucose homeostasis
|
Any process that modulates the frequency, rate or extent of gluconeogenesis as an integral part of cellular glucose homeostasis.
|
OGT,
RANBP2,
SESN2
|
GO:0090527
|
BP
|
actin filament reorganization
|
A process that is carried out at the cellular level which results in dynamic structural changes to the arrangement of actin filaments.
|
FRY
|
GO:0090557
|
BP
|
establishment of endothelial intestinal barrier
|
The establishment of a barrier between endothelial cell layers of the intestine to exert specific and selective control over the passage of water and solutes, thus allowing formation and maintenance of compartments that differ in fluid and solute composition.
|
TJP1,
TJP2,
F11R
|
GO:0090559
|
BP
|
regulation of membrane permeability
|
Any process that modulates the frequency, rate or extent of the passage or uptake of molecules by a membrane.
|
TJP2,
F11R
|
GO:0090611
|
BP
|
ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway
|
The chemical reactions and pathways resulting in the breakdown of a protein or peptide, via the multivesicular body (MVB) sorting pathway; proteins are sorted into MVBs, and delivered to a lysosome/vacuole for degradation. This process is independent of ubiquitination.
|
VPS4B,
PDCD6IP,
CHMP4B
|
GO:0090625
|
BP
|
mRNA cleavage involved in gene silencing by siRNA
|
The process in which small interfering RNAs (siRNAs) direct the cleavage of target mRNAs. Once incorporated into a RNA-induced silencing complex (RISC), a siRNA will typically direct cleavage by base pairing with perfect or near-perfect complementarity to the target mRNA.
|
AGO2
|
GO:0090630
|
BP
|
activation of GTPase activity
|
Any process that initiates the activity of an inactive GTPase through the replacement of GDP by GTP.
|
TAX1BP3,
ARHGEF10,
TBC1D4,
TBC1D12,
TBC1D8,
TBC1D3H,
AKT2,
WNT5A,
EIF5,
TBC1D8B,
TIAM1,
RALGAPA2,
RABGAP1L,
GRTP1,
ARHGEF16,
TBC1D9B,
RALGAPA1,
TBC1D3C,
TBC1D9,
SYDE1,
RALGAPB,
TBC1D3,
TBC1D16,
TBC1D15,
TBC1D5,
USP6NL,
RUNDC1,
EVI5L,
DOCK7,
NDEL1,
ECT2,
TBC1D14,
CORO1C,
TBC1D2B,
RABGAP1
|
GO:0090646
|
BP
|
mitochondrial tRNA processing
|
The process in which a pre-tRNA molecule is converted to a mature tRNA, ready for addition of an aminoacyl group, in the mitochondrion.
|
KIAA0391,
HSD17B10,
ELAC2
|
GO:0090650
|
BP
|
cellular response to oxygen-glucose deprivation
|
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the deprivation of oxygen and glucose.
|
AIFM1
|
GO:0090656
|
BP
|
t-circle formation
|
A telomere maintenance process that results in the formation of a telomeric circle, or t-circle. A t-circle is an extrachromosomal duplex or single-stranded circular DNA molecule composed of t-arrays. T-circles are involved in the control of telomere length via alternative-lengthening of telomeres (ALT) pathway and telomere rapid deletion (TRD).
|
ERCC1
|
GO:0090662
|
BP
|
ATP hydrolysis coupled transmembrane transport
|
The transport of molecules across a membrane and against an electrochemical gradient, using energy from ATP hydrolysis.
|
ATP1B1,
ATP1B3
|
GO:0090666
|
BP
|
scaRNA localization to Cajal body
|
A process in which a small Cajal body-specific RNA is transported to, or maintained in, a Cajal body.
|
TCP1,
CCT2
|
GO:0090669
|
BP
|
telomerase RNA stabilization
|
Prevention of degradation of telomerase RNA (TERC) molecules.
|
DKC1
|
GO:0090675
|
BP
|
intermicrovillar adhesion
|
The biological adhesion process by which adjacent microvilli attach to each other through Ca(2+)-dependent adhesion links made of protocadherin-24 and mucin-like protocadherin.
|
CDHR2
|
GO:0097006
|
BP
|
regulation of plasma lipoprotein particle levels
|
Any process involved in the maintenance of internal levels of plasma lipoprotein particles within an organism.
|
LPCAT3,
DGAT2
|
GO:0097009
|
BP
|
energy homeostasis
|
Any process involved in the balance between food intake (energy input) and energy expenditure.
|
ACACB,
EDN2,
STAT3,
PIK3CA,
LEPR,
AMPD3,
MEX3C,
CRTC3,
NR4A3,
OMA1,
MRAP2
|
GO:0097010
|
BP
|
eukaryotic translation initiation factor 4F complex assembly
|
The aggregation, arrangement and bonding together of a set of components to form the eukaryotic translation initiation factor 4F complex.
|
EIF4B
|
GO:0097011
|
BP
|
cellular response to granulocyte macrophage colony-stimulating factor stimulus
|
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a granulocyte macrophage colony-stimulating factor stimulus.
|
NPR2,
ZFP36,
MAPK1,
AKT1,
ZFP36L2
|
GO:0097028
|
BP
|
dendritic cell differentiation
|
The process in which a precursor cell type acquires the specialized features of a dendritic cell. A dendritic cell is a leukocyte of dendritic lineage specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation.
|
LYN,
GAS6,
LILRB1,
AZI2
|
GO:0097029
|
BP
|
mature conventional dendritic cell differentiation
|
The process in which antigen-activated dendritic cells acquire the specialized features of a mature conventional dendritic cell. Mature conventional dendritic cells upregulate the surface expression of MHC molecules, chemokine receptors and adhesion molecules, and increase the number of dendrites (cytoplasmic protrusions) in preparation for migration to lymphoid organs where they present antigen to T cells.
|
F2RL1
|
GO:0097033
|
BP
|
mitochondrial respiratory chain complex III biogenesis
|
The biogenesis of a mitochondrial respiratory chain complex III (also known as cytochrome bc(1) complex or ubiquinol-cytochrome c reductase), a protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. Includes the synthesis of constituent proteins and their aggregation, arrangement and bonding together.
|
UQCC3
|
GO:0097035
|
BP
|
regulation of membrane lipid distribution
|
Any process that modulates the proportions or spatial arrangement of lipids in a cellular membrane.
|
TRIAP1,
PRELID1
|
GO:0097039
|
BP
|
protein linear polyubiquitination
|
A protein ubiquitination process in which a linear polymer of ubiquitin, formed by the amino-terminal methionine (M1) of one ubiquitin molecule and by the carboxy-terminal glycine (G76) of the next, is added to a protein.
|
RNF216
|
GO:0097045
|
BP
|
phosphatidylserine exposure on blood platelet
|
A phospholipid scrambling process that results in the appearance of phosphatidylserine on the surface of activated blood platelets, and triggers the clotting system.
|
ANO6
|
GO:0097049
|
BP
|
motor neuron apoptotic process
|
Any apoptotic process in a motor neuron, an efferent neuron that passes from the central nervous system or a ganglion toward or to a muscle and conducts an impulse that causes movement.
|
FAS,
FADD
|
GO:0097050
|
BP
|
type B pancreatic cell apoptotic process
|
Any apoptotic process in a type B pancreatic cell, a cell located towards center of the islets of Langerhans that secretes insulin.
|
RYR2,
CAPN10
|
GO:0097051
|
BP
|
establishment of protein localization to endoplasmic reticulum membrane
|
The directed movement of a protein to a specific location in the endoplasmic reticulum membrane.
|
RAB3GAP1,
RAB3GAP2
|
GO:0097052
|
BP
|
L-kynurenine metabolic process
|
The chemical reactions and pathways involving L-kynurenine, the L-enantiomer of the amino acid kynurenine (3-(2-aminobenzoyl)-alanine).
|
GOT2
|
GO:0097053
|
BP
|
L-kynurenine catabolic process
|
The chemical reactions and pathways resulting in the breakdown of L-kynurenine, the L-enantiomer of the amino acid kynurenine (3-(2-aminobenzoyl)-alanine).
|
KYNU
|
GO:0097055
|
BP
|
agmatine biosynthetic process
|
The chemical reactions and pathways resulting in the formation of agmatine ((4-aminobutyl)guanidine, NH2-CH2-CH2-CH2-CH2-NH-C(-NH2)(=NH)). Agmatine is the decarboxylation product of the amino acid arginine and is an intermediate in polyamine biosynthesis. It is synthesized in the brain, stored in synaptic vesicles, accumulated by uptake, released by membrane depolarization, and inactivated by agmatinase.
|
AGMAT
|
GO:0097056
|
BP
|
selenocysteinyl-tRNA(Sec) biosynthetic process
|
The chemical reactions and pathways resulting in the formation of selenocysteinyl-tRNA(Sec). This process occurs through the following steps: a unique serine-tRNA with a UGA recognizing anticodon is first aminoacylated with serine; this is then phosphorylated by phosphoseryl-tRNA[Ser]Sec kinase; lastly, selenium is swapped for the phosphate on the serine.
|
SARS,
SEPSECS
|
GO:0097061
|
BP
|
dendritic spine organization
|
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a dendritic spine. A dendritic spine is a specialized protrusion from a neuronal dendrite and is involved in synaptic transmission.
|
ARF1
|
GO:0097062
|
BP
|
dendritic spine maintenance
|
The organization process that preserves a dendritic spine in a stable functional or structural state. A dendritic spine is a specialized protrusion from a neuronal dendrite and is involved in synaptic transmission.
|
ITPKA,
ITGA3,
MTMR2,
CTTN
|
GO:0097066
|
BP
|
response to thyroid hormone
|
A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thyroid hormone stimulus.
|
ANXA2,
AKR1B1
|
GO:0097067
|
BP
|
cellular response to thyroid hormone stimulus
|
A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thyroid hormone stimulus.
|
CTSL,
CTSB,
CTSH,
KIT,
CTSS,
LMO2,
RDX,
KLF9,
PPARGC1A
|
GO:0097069
|
BP
|
cellular response to thyroxine stimulus
|
A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thyroxine stimulus.
|
GCLC,
GCLM
|
GO:0097070
|
BP
|
ductus arteriosus closure
|
The morphogenesis process in which the ductus arteriosus changes to no longer permit blood flow after birth. The ductus arteriosus is the shunt between the aorta and the pulmonary artery which allows blood to bypass the fetus' lungs.
|
HPGD
|
GO:0097084
|
BP
|
vascular smooth muscle cell development
|
The process aimed at the progression of a vascular smooth muscle cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. A vascular smooth muscle cell is a non-striated, elongated, spindle-shaped cell found lining the blood vessels.
|
ADM,
HES1,
SGCB
|
GO:0097089
|
BP
|
methyl-branched fatty acid metabolic process
|
The chemical reactions and pathways involving methyl-branched fatty acids, aliphatic monocarboxylic acids with methyl branches on the main chain.
|
SLC27A2
|
GO:0097091
|
BP
|
synaptic vesicle clustering
|
The process that results in grouping synaptic vesicles, prior to release, at a specialized patch of the presynaptic membrane referred to as the active zone.
|
NLGN1
|
GO:0097094
|
BP
|
craniofacial suture morphogenesis
|
The process in which any suture between cranial and/or facial bones is generated and organized.
|
FOXN3,
MMP14,
MMP16,
RAB23
|
GO:0097102
|
BP
|
endothelial tip cell fate specification
|
The process involved in the specification of identity of an endothelial tip cell. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment. An endothelial tip cell is a specialized endothelial cell localized to the leading edge of an angiogenic sprout that senses extracellular signals and guides the directed growth of blood vessels.
|
NRP1
|
GO:0097104
|
BP
|
postsynaptic membrane assembly
|
The aggregation, arrangement and bonding together of a set of components to form a postsynaptic membrane, a specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft).
|
NLGN1,
NRXN1
|