|
GO:0089711
|
BP
|
L-glutamate transmembrane transport
|
The directed movement of L-glutamate across a membrane.
|
SLC25A12,
SLC1A3,
SLC1A2,
SLC1A6,
SLC25A13,
SLC7A11
|
|
GO:0089712
|
BP
|
L-aspartate transmembrane transport
|
The directed movement of L-aspartate across a membrane.
|
SLC25A12,
SLC1A6,
SLC25A13
|
|
GO:0090002
|
BP
|
establishment of protein localization to plasma membrane
|
The directed movement of a protein to a specific location in the plasma membrane.
|
ROCK2,
FLOT1,
TNF,
JUP,
EZR,
CDH2,
RDX,
ACTN2,
S100A10,
TSPAN5,
TMEM150A,
TTC7B,
MPP5,
TSPAN14,
PKP2,
PACSIN1,
SPTBN4,
PKP3,
F11R
|
|
GO:0090003
|
BP
|
regulation of establishment of protein localization to plasma membrane
|
Any process that modulates the frequency, rate or extent of the directed movement of a protein to a specific location in the plasma membrane.
|
AR,
LDLRAP1
|
|
GO:0090004
|
BP
|
positive regulation of establishment of protein localization to plasma membrane
|
Any process that increases the frequency, rate or extent of the directed movement of a protein to a specific location in the plasma membrane.
|
RAMP3,
ITGB1,
EZR,
ITGA3,
PIK3R1,
AKT1,
PRKCI,
STX4,
DLG1,
PLS1,
ARHGEF16,
GPER1,
CIB1,
SORBS1,
WNK3,
RANGRF
|
|
GO:0090005
|
BP
|
negative regulation of establishment of protein localization to plasma membrane
|
Any process that decreases the frequency, rate or extent of the directed movement of a protein to a specific location in the plasma membrane.
|
RHOQ,
PPP2R5A,
PID1,
TMBIM1,
TMEM59
|
|
GO:0090009
|
BP
|
primitive streak formation
|
The developmental process pertaining to the initial formation of the primitive streak from unspecified parts. The primitive streak is a ridge of cells running along the midline of the embryo where the mesoderm ingresses. It defines the anterior-posterior axis.
|
LRP6,
ETS2,
OTX2,
WNT5A,
HHEX
|
|
GO:0090022
|
BP
|
regulation of neutrophil chemotaxis
|
Any process that modulates the frequency, rate, or extent of neutrophil chemotaxis. Neutrophil chemotaxis is the directed movement of a neutrophil cell, the most numerous polymorphonuclear leukocyte found in the blood, in response to an external stimulus, usually an infection or wounding.
|
MPP1,
JAM3
|
|
GO:0090023
|
BP
|
positive regulation of neutrophil chemotaxis
|
Any process that increases the frequency, rate, or extent of neutrophil chemotaxis. Neutrophil chemotaxis is the directed movement of a neutrophil cell, the most numerous polymorphonuclear leukocyte found in the blood, in response to an external stimulus, usually an infection or wounding.
|
CD74,
CXCL1,
CXCL8,
RAC2,
CXCL2,
C5AR1,
CXCR2,
THBS4,
TIRAP,
RAC1,
C1QBP,
CAMK1D
|
|
GO:0090024
|
BP
|
negative regulation of neutrophil chemotaxis
|
Any process that decreases the frequency, rate, or extent of neutrophil chemotaxis. Neutrophil chemotaxis is the directed movement of a neutrophil cell, the most numerous polymorphonuclear leukocyte found in the blood, in response to an external stimulus, usually an infection or wounding.
|
SLIT2
|
|
GO:0090025
|
BP
|
regulation of monocyte chemotaxis
|
Any process that modulates the frequency, rate, or extent of monocyte chemotaxis.
|
LYN
|
|
GO:0090026
|
BP
|
positive regulation of monocyte chemotaxis
|
Any process that increases the frequency, rate, or extent of monocyte chemotaxis.
|
SERPINE1,
HMGB1,
CCL2,
CCL5,
S100A7,
CXCL12,
PLA2G7,
ANO6
|
|
GO:0090027
|
BP
|
negative regulation of monocyte chemotaxis
|
Any process that decreases the frequency, rate, or extent of monocyte chemotaxis.
|
GREM1,
SLIT2,
NBL1
|
|
GO:0090035
|
BP
|
positive regulation of chaperone-mediated protein complex assembly
|
Any process that increases the frequency, rate, or extent of chaperone-mediated protein complex assembly. Chaperone-mediated protein complex assembly is the aggregation, arrangement and bonding together of a set of components to form a protein complex, mediated by chaperone molecules that do not form part of the finished complex.
|
HDAC6,
STUB1
|
|
GO:0090036
|
BP
|
regulation of protein kinase C signaling
|
Any process that modulates the frequency, rate, or extent of a series of reactions, mediated by the intracellular serine/threonine kinase protein kinase C, which occurs as a result of a single trigger reaction or compound.
|
ULK4
|
|
GO:0090037
|
BP
|
positive regulation of protein kinase C signaling
|
Any process that increases the frequency, rate, or extent of a series of reactions, mediated by the intracellular serine/threonine kinase protein kinase C, which occurs as a result of a single trigger reaction or compound.
|
VEGFA,
ADRA1A,
FLT4,
WNT5A
|
|
GO:0090038
|
BP
|
negative regulation of protein kinase C signaling
|
Any process that decreases the frequency, rate, or extent of a series of reactions, mediated by the intracellular serine/threonine kinase protein kinase C, which occurs as a result of a single trigger reaction or compound.
|
MYADM
|
|
GO:0090042
|
BP
|
tubulin deacetylation
|
The removal of an acetyl group from tubulin. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid.
|
SIRT2,
HDAC6
|
|
GO:0090043
|
BP
|
regulation of tubulin deacetylation
|
Any process that modulates the frequency, rate or extent of tubulin deacetylation. Tubulin deacetylation is the removal of an acetyl group from a protein amino acid.
|
TADA3,
NEK3,
EP300
|
|
GO:0090045
|
BP
|
positive regulation of deacetylase activity
|
Any process that activates or increases the frequency, rate or extent of deacetylase activity, the catalysis of the hydrolysis of an acetyl group or groups from a substrate molecule.
|
MAPK8
|
|
GO:0090050
|
BP
|
positive regulation of cell migration involved in sprouting angiogenesis
|
Any process that increases the frequency, rate or extent of cell migration involved in sprouting angiogenesis. Cell migration involved in sprouting angiogenesis is the orderly movement of endothelial cells into the extracellular matrix in order to form new blood vessels contributing to the process of sprouting angiogenesis.
|
SRPX2,
VEGFA,
PTGS2,
HDAC7,
CIB1,
HDAC9
|
|
GO:0090051
|
BP
|
negative regulation of cell migration involved in sprouting angiogenesis
|
Any process that decreases the frequency, rate or extent of cell migration involved in sprouting angiogenesis. Cell migration involved in sprouting angiogenesis is the orderly movement of endothelial cells into the extracellular matrix in order to form new blood vessels contributing to the process of sprouting angiogenesis.
|
ITGB1BP1,
KLF4,
NOTCH1,
RHOA,
MAP2K5,
PDCD10,
DLL4,
HDAC5,
STARD13
|
|
GO:0090068
|
BP
|
positive regulation of cell cycle process
|
Any process that increases the rate, frequency or extent of a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events.
|
NUDT16
|
|
GO:0090071
|
BP
|
negative regulation of ribosome biogenesis
|
Any process that decreases the rate, frequency or extent of ribosome biogenesis. Ribosome biogenesis is the cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits.
|
PTEN,
MALSU1
|
|
GO:0090073
|
BP
|
positive regulation of protein homodimerization activity
|
Any process that increases the frequency, rate or extent of protein homodimerization, interacting selectively with an identical protein to form a homodimer.
|
TIRAP,
MEF2C,
GNL3L
|
|
GO:0090074
|
BP
|
negative regulation of protein homodimerization activity
|
Any process that decreases the frequency, rate or extent of protein homodimerization, interacting selectively with an identical protein to form a homodimer.
|
SPAG9,
HSPA5,
ID1
|
|
GO:0090080
|
BP
|
positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway
|
The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands resulting in an increase in the rate or frequency of a MAPKKK cascade.
|
FGFR1,
KL
|
|
GO:0090082
|
BP
|
positive regulation of heart induction by negative regulation of canonical Wnt signaling pathway
|
Any process that decreases the rate, frequency or extent of canonical Wnt signaling pathway that positively regulates heart induction. Canonical Wnt signaling pathway involved in heart induction is the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes.
|
DKK1
|
|
GO:0090083
|
BP
|
regulation of inclusion body assembly
|
Any process that modulates the rate, frequency, or extent of inclusion body assembly. Inclusion body assembly is the aggregation, arrangement and bonding together of a set of components to form an inclusion body.
|
BAG5,
SNCAIP
|
|
GO:0090084
|
BP
|
negative regulation of inclusion body assembly
|
Any process that decreases the rate, frequency, or extent of inclusion body assembly. Inclusion body assembly is the aggregation, arrangement and bonding together of a set of components to form an inclusion body.
|
DNAJB6,
HSPA1A,
HSPA1B,
DNAJB1,
DNAJB2,
HSF1,
DNAJA4
|
|
GO:0090085
|
BP
|
regulation of protein deubiquitination
|
Any process that modulates the frequency, rate or extent of protein deubiquitination. Protein deubiquitination is the removal of one or more ubiquitin groups from a protein.
|
ITCH
|
|
GO:0090090
|
BP
|
negative regulation of canonical Wnt signaling pathway
|
Any process that decreases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes.
|
KIAA0922,
PSMD11,
PSMD12,
AXIN1,
PSMD3,
SIAH2,
FOXO3,
SNAI2,
PARK2,
FZD6,
GREM1,
CTNND1,
LRP6,
PSMD10,
DKK1,
LATS1,
APOE,
IGFBP1,
UBC,
GLI3,
BMP2,
PSMC3,
IGFBP2,
EGR1,
CDH2,
PSMB1,
IGFBP4,
IGFBP6,
APC,
PSMA1,
PSMA2,
PSMA3,
PSMA4,
PSMB8,
PSMB9,
PSMB4,
PSMB5,
DDIT3,
PSMC2,
PSMB10,
WNT5A,
PSMC4,
NOTCH1,
SOX9,
CSNK1A1,
PSMB3,
GSK3B,
PSMD7,
PSME3,
PSMC1,
PSMC6,
RBX1,
RPS27A,
UBA52,
DAB2,
CAV1,
AES,
FOXO1,
STK4,
PSMD2,
G3BP1,
HDAC1,
CUL3,
RAPGEF1,
PSME4,
MAPK14,
PTPRO,
KLHL12,
SFRP5,
SFRP4,
JADE1,
SOSTDC1,
NPHP3,
SFRP1,
DACT3,
CTHRC1,
PRICKLE1,
PFDN5,
SOST,
WNT5B,
BICC1,
SOX17,
CHD8,
TCF7L2,
CYLD,
LATS2,
DACT1,
DKK3,
DKK2,
LIMD1,
INVS
|
|
GO:0090091
|
BP
|
positive regulation of extracellular matrix disassembly
|
Any process that increases the rate, frequency or extent of extracellular matrix disassembly. Extracellular matrix disassembly is a process that results in the breakdown of the extracellular matrix.
|
MFI2,
TGFB2,
FSCN1
|
|
GO:0090094
|
BP
|
metanephric cap mesenchymal cell proliferation involved in metanephros development
|
The multiplication or reproduction of metanephric cap mesenchymal cells, resulting in the expansion of the cell population. A metanephric cap mesenchymal cell is a mesenchymal cell that has condensed with other mesenchymal cells surrounding the ureteric bud tip.
|
OSR1
|
|
GO:0090096
|
BP
|
positive regulation of metanephric cap mesenchymal cell proliferation
|
Any process that increases the frequency, rate, or extent of metanephric cap mesenchymal cell proliferation. Metanephric cap mesenchymal cell proliferation is the multiplication or reproduction of metanephric cap mesenchymal cells, resulting in the expansion of the cell population. A metanephric cap mesenchymal cell is a mesenchymal cell that has condensed with other mesenchymal cells surrounding the ureteric bud tip.
|
MYC
|
|
GO:0090102
|
BP
|
cochlea development
|
The progression of the cochlea over time from its formation to the mature structure. The cochlea is the snail-shaped portion of the inner ear that is responsible for the detection of sound.
|
SOBP,
KCNK3,
CCNA2,
GABRA5,
HOXA1,
HES1,
IFT27
|
|
GO:0090103
|
BP
|
cochlea morphogenesis
|
The process in which the cochlea is generated and organized.
|
TBX1,
GLI2,
ZEB1,
WNT5A,
SOX9,
HOXA1,
RAC1,
PTK7,
CTHRC1
|
|
GO:0090107
|
BP
|
regulation of high-density lipoprotein particle assembly
|
Any process that modulates the frequency, rate, or extent of high-density lipoprotein particle assembly. High-density lipoprotein particle assembly is the aggregation and arrangement of proteins and lipids to form a high-density lipoprotein particle.
|
ABCA1
|
|
GO:0090108
|
BP
|
positive regulation of high-density lipoprotein particle assembly
|
Any process that increases the frequency, rate, or extent of high-density lipoprotein particle assembly. High-density lipoprotein particle assembly is the aggregation and arrangement of proteins and lipids to form a high-density lipoprotein particle.
|
NR1H2
|
|
GO:0090110
|
BP
|
cargo loading into COPII-coated vesicle
|
The formation of a macromolecular complex between the COPII coat proteins and proteins and/or lipoproteins that are going to be transported by the COPII vesicle to the Golgi.
|
RAB1A
|
|
GO:0090114
|
BP
|
COPII-coated vesicle budding
|
The evagination of an endoplasmic reticulum membrane, resulting in formation of a COPII-coated vesicle.
|
VAPB,
VAPA
|
|
GO:0090116
|
BP
|
C-5 methylation of cytosine
|
The covalent transfer of a methyl group to C-5 of cytosine in a DNA molecule.
|
DNMT1,
DNMT3B
|
|
GO:0090118
|
BP
|
receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport
|
A receptor-mediated endocytosis process that results in the uptake of low-density lipoprotein by cells.
|
LRP6,
LDLRAP1
|
|
GO:0090129
|
BP
|
positive regulation of synapse maturation
|
Any process that increases the extent of synapse maturation, the process that organizes a synapse so that it attains its fully functional state.
|
CDC20,
NRXN1
|
|
GO:0090131
|
BP
|
mesenchyme migration
|
The process in which the population of cells that make up a mesenchyme undergo directed movement.
|
ACTA2,
ACTG2,
ACTC1
|
|
GO:0090135
|
BP
|
actin filament branching
|
The formation of daughter actin filament branches at an angle on the sides of preexisting mother filaments.
|
CDC42,
CORO1B
|
|
GO:0090136
|
BP
|
epithelial cell-cell adhesion
|
The attachment of an epithelial cell to another epithelial cell via adhesion molecules.
|
ITGB5,
CTNNA1,
CDC42,
BVES,
CAMSAP3
|
|
GO:0090138
|
BP
|
regulation of actin cytoskeleton organization by cell-cell adhesion
|
Any cell-cell adhesion process that modulates the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins.
|
JAM3
|
|
GO:0090140
|
BP
|
regulation of mitochondrial fission
|
Any process that modulates the rate, frequency or extent of mitochondrial fission. Mitochondrial fission is the division of a mitochondrion within a cell to form two or more separate mitochondrial compartments.
|
STAT2,
DHODH
|
|
GO:0090141
|
BP
|
positive regulation of mitochondrial fission
|
Any process that increases the rate, frequency or extent of mitochondrial fission. Mitochondrial fission is the division of a mitochondrion within a cell to form two or more separate mitochondrial compartments.
|
PARK2,
DCN,
BNIP3,
MIEF2,
PINK1,
MFF
|
|
GO:0090148
|
BP
|
membrane fission
|
A process that is carried out at the cellular level which results in the separation of a single continuous membrane into two membranes.
|
CHMP4B,
SPAST,
SH3GLB1
|
|
GO:0090150
|
BP
|
establishment of protein localization to membrane
|
The directed movement of a protein to a specific location in a membrane.
|
NPC1,
BID,
RAB11A,
RAB11B,
COLQ
|
|
GO:0090156
|
BP
|
cellular sphingolipid homeostasis
|
Any biological process involved in the maintenance of an internal steady state of sphingolipids at the level of the cell.
|
ORMDL2
|
|
GO:0090160
|
BP
|
Golgi to lysosome transport
|
The directed movement of substances from the Golgi to lysosomes.
|
LAMP1,
EHD3,
ANKFY1
|
|
GO:0090161
|
BP
|
Golgi ribbon formation
|
The formation of a continuous ribbon of interconnected Golgi stacks of flat cisternae.
|
STX6,
VAMP4,
GOLGA2,
OPTN,
TMED5
|
|
GO:0090162
|
BP
|
establishment of epithelial cell polarity
|
The specification and formation of anisotropic intracellular organization of an epithelial cell.
|
CYTH3,
HES1,
MPP5,
FBF1,
PARD3,
FERMT1,
FRMD4A,
FRMD4B
|
|
GO:0090166
|
BP
|
Golgi disassembly
|
A cellular process that results in the breakdown of a Golgi apparatus that contributes to Golgi inheritance.
|
CDK1,
GOLGA2,
GBF1,
VRK1
|
|
GO:0090168
|
BP
|
Golgi reassembly
|
The reformation of the Golgi following its breakdown and partitioning contributing to Golgi inheritance.
|
YWHAZ,
VCPIP1,
PDCD10
|
|
GO:0090169
|
BP
|
regulation of spindle assembly
|
Any process that modulates the rate, frequency or extent of spindle assembly. Spindle assembly is the aggregation, arrangement and bonding together of a set of components to form the spindle, the array of microtubules and associated molecules that serves to move duplicated chromosomes apart.
|
SENP6
|
|
GO:0090170
|
BP
|
regulation of Golgi inheritance
|
Any process that modulates the rate, frequency or extent of Golgi inheritance. Golgi inheritance is the partitioning of Golgi apparatus between daughter cells at cell division.
|
MAPK3,
MAPK1,
MAP2K2,
MAP2K1
|
|
GO:0090177
|
BP
|
establishment of planar polarity involved in neural tube closure
|
Coordinated organization of groups of cells in the plane of an epithelium that contributes to the closure of the neural tube.
|
CTHRC1
|
|
GO:0090179
|
BP
|
planar cell polarity pathway involved in neural tube closure
|
The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors that modulates the establishment of planar polarity contributing to neural tube closure.
|
WNT5A,
PTK7,
SFRP1
|
|
GO:0090181
|
BP
|
regulation of cholesterol metabolic process
|
Any process that modulates the rate, frequency, or extent of cholesterol metabolism, the chemical reactions and pathways involving cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.
|
ACADVL,
SERPINA12,
DGAT2,
NR1H4,
LMF1
|
|
GO:0090184
|
BP
|
positive regulation of kidney development
|
Any process that increases the rate, frequency or extent of kidney development. Kidney development is the process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine.
|
BMP4,
SOX9,
SOX8
|
|
GO:0090187
|
BP
|
positive regulation of pancreatic juice secretion
|
Any process that increases the rate, frequency or extent of pancreatic juice secretion, the regulated release of pancreatic juice by the exocrine pancreas into the upper part of the intestine.
|
SCT,
NR1H2
|
|
GO:0090188
|
BP
|
negative regulation of pancreatic juice secretion
|
Any process that decreases the rate, frequency or extent of pancreatic juice secretion, the regulated release of pancreatic juice by the exocrine pancreas into the upper part of the intestine.
|
NR1H3,
WNK3,
WNK1
|
|
GO:0090190
|
BP
|
positive regulation of branching involved in ureteric bud morphogenesis
|
Any process that increases the rate, frequency or extent of branching involved in ureteric bud morphogenesis, the process in which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules.
|
GREM1,
AGT,
TGFB1,
VEGFA,
SOX9,
AGTR2,
SOX8,
PAX8,
WNT2B,
LGR4
|
|
GO:0090191
|
BP
|
negative regulation of branching involved in ureteric bud morphogenesis
|
Any process that decreases the rate, frequency or extent of branching involved in ureteric bud morphogenesis, the process in which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules.
|
GREM1,
BMP4
|
|
GO:0090194
|
BP
|
negative regulation of glomerulus development
|
Any process that decreases the rate, frequency or extent of glomerulus development, the progression of the glomerulus over time from its initial formation until its mature state. The glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney.
|
BMP4
|
|
GO:0090195
|
BP
|
chemokine secretion
|
The regulated release of chemokines from a cell.
|
F2RL1
|
|
GO:0090197
|
BP
|
positive regulation of chemokine secretion
|
Any process that increases the rate, frequency or extent of chemokine secretion, the regulated release of chemokines from a cell.
|
IL33,
LPL,
CSF1R,
IL4R,
IL1RL1,
PYCARD
|
|
GO:0090198
|
BP
|
negative regulation of chemokine secretion
|
Any process that decreases the rate, frequency or extent of chemokine secretion, the regulated release of chemokines from a cell.
|
F2RL1
|
|
GO:0090200
|
BP
|
positive regulation of release of cytochrome c from mitochondria
|
Any process that increases the rate, frequency or extent of release of cytochrome c from mitochondria, the process in which cytochrome c is enabled to move from the mitochondrial intermembrane space into the cytosol, which is an early step in apoptosis and leads to caspase activation.
|
PDCD5,
BCL2L11,
TP53,
MMP9,
PPIF,
TNFSF10,
BID,
PLAUR,
BAX,
BNIP3,
MLLT11,
PMAIP1,
BAD,
FAM162A,
MOAP1,
APOPT1,
GPER1,
BBC3,
PINK1,
MFF,
PYCARD
|
|
GO:0090201
|
BP
|
negative regulation of release of cytochrome c from mitochondria
|
Any process that decreases the rate, frequency or extent of release of cytochrome c from mitochondria, the process in which cytochrome c is enabled to move from the mitochondrial intermembrane space into the cytosol, which is an early step in apoptosis and leads to caspase activation.
|
TRIAP1,
PARK2,
OPA1,
NOL3,
PSMD10,
LMNA,
IGF1,
GPX1,
HGF,
PPIF,
AKT1,
FXN,
PRELID1
|
|
GO:0090204
|
BP
|
protein localization to nuclear pore
|
A process in which a protein is transported to, or maintained in, a nuclear pore.
|
NUTF2,
OSBPL8
|
|
GO:0090205
|
BP
|
positive regulation of cholesterol metabolic process
|
Any process that increases the rate, frequency, or extent of cholesterol metabolism, the chemical reactions and pathways involving cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.
|
LDLRAP1
|
|
GO:0090207
|
BP
|
regulation of triglyceride metabolic process
|
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving triglyceride, any triester of glycerol.
|
SERPINA12,
LMF1,
PANK2,
TBL1XR1
|
|
GO:0090212
|
BP
|
negative regulation of establishment of blood-brain barrier
|
Any process that decreases the rate, frequency or extent of the establishment of the blood-brain barrier, a selectively permeable structural and functional barrier that exists between the capillaries and the brain.
|
TRPV1
|
|
GO:0090218
|
BP
|
positive regulation of lipid kinase activity
|
Any process that increases the frequency, rate or extent of lipid kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a simple or complex lipid.
|
F2,
EEF1A2
|
|
GO:0090219
|
BP
|
negative regulation of lipid kinase activity
|
Any process that decreases the frequency, rate or extent of lipid kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a simple or complex lipid.
|
PPP2R5A
|
|
GO:0090222
|
BP
|
centrosome-templated microtubule nucleation
|
The 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates from the centrosome.
|
NIN
|
|
GO:0090230
|
BP
|
regulation of centromere complex assembly
|
Any process that modulates the rate, frequency, or extent of centromere complex assembly, the aggregation, arrangement and bonding together of proteins and centromeric DNA molecules to form a centromeric protein-DNA complex.
|
RB1,
H3F3A
|
|
GO:0090231
|
BP
|
regulation of spindle checkpoint
|
Any process that modulates the rate, frequency, or extent of the spindle checkpoint, a cell cycle checkpoint that delays the metaphase/anaphase transition until the spindle is correctly assembled and oriented, and chromosomes are attached to the spindle.
|
GSG2,
USP44
|
|
GO:0090232
|
BP
|
positive regulation of spindle checkpoint
|
Any process that increases the rate, frequency, or extent of the spindle checkpoint, a cell cycle checkpoint that delays the metaphase/anaphase transition until the spindle is correctly assembled and oriented, and chromosomes are attached to the spindle.
|
NDRG1
|
|
GO:0090234
|
BP
|
regulation of kinetochore assembly
|
Any process that modulates the rate, frequency, or extent of kinetochore assembly, the aggregation, arrangement and bonding together of a set of components to form the kinetochore, a multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules.
|
SENP6
|
|
GO:0090235
|
BP
|
regulation of metaphase plate congression
|
Any process that modulates the rate, frequency, or extent of metaphase plate congression, the alignment of chromosomes at the metaphase plate, a plane halfway between the poles of the spindle.
|
MAD1L1
|
|
GO:0090237
|
BP
|
regulation of arachidonic acid secretion
|
Any process that modulates the rate, frequency, or extent of arachidonic acid secretion, the controlled release of arachidonic acid from a cell or a tissue.
|
SYK
|
|
GO:0090238
|
BP
|
positive regulation of arachidonic acid secretion
|
Any process that increases the rate, frequency, or extent of arachidonic acid secretion, the controlled release of arachidonic acid from a cell or a tissue.
|
MIF
|
|
GO:0090240
|
BP
|
positive regulation of histone H4 acetylation
|
Any process that increases the rate, frequency, or extent of histone H4 acetylation, the modification of histone H4 by the addition of an acetyl group.
|
MUC1
|
|
GO:0090244
|
BP
|
Wnt signaling pathway involved in somitogenesis
|
The series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell and ending with a change in cell state that contributes to somitogenesis.
|
AXIN1,
LRP6,
DKK1,
SFRP1
|
|
GO:0090245
|
BP
|
axis elongation involved in somitogenesis
|
The developmental growth that results in the elongation of the rostral-caudal axis that contributes to somitogenesis.
|
LRP6,
MED12
|
|
GO:0090246
|
BP
|
convergent extension involved in somitogenesis
|
The morphogenetic process in which a presomitic mesoderm narrows along the left-right axis and lengthens in the rostral-caudal axis contributing to somitogenesis.
|
SFRP1
|
|
GO:0090258
|
BP
|
negative regulation of mitochondrial fission
|
Any process that decreases the rate, frequency or extent of mitochondrial fission. Mitochondrial fission is the division of a mitochondrion within a cell to form two or more separate mitochondrial compartments.
|
PINK1,
PPARGC1A
|
|
GO:0090259
|
BP
|
regulation of retinal ganglion cell axon guidance
|
Any process that modulates the frequency, rate, or extent of retinal ganglion cell axon guidance, the process in which the migration of an axon growth cone of a retinal ganglion cell (RGC) is directed to its target in the brain in response to a combination of attractive and repulsive cues.
|
NRP1,
VEGFA
|
|
GO:0090260
|
BP
|
negative regulation of retinal ganglion cell axon guidance
|
Any process that decreases the frequency, rate, or extent of retinal ganglion cell axon guidance, the process in which the migration of an axon growth cone of a retinal ganglion cell (RGC) is directed to its target in the brain in response to a combination of attractive and repulsive cues.
|
SLIT2,
PTPRO
|
|
GO:0090261
|
BP
|
positive regulation of inclusion body assembly
|
Any process that increases the rate, frequency, or extent of inclusion body assembly. Inclusion body assembly is the aggregation, arrangement and bonding together of a set of components to form an inclusion body.
|
CDC34,
HSF1
|
|
GO:0090263
|
BP
|
positive regulation of canonical Wnt signaling pathway
|
Any process that increases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes.
|
PSMD11,
PSMD12,
ARNTL,
AXIN1,
PSMD3,
DAPK3,
LGR5,
LRP6,
PSMD10,
UBR5,
TNKS,
CTDNEP1,
COL1A1,
WNT2,
UBC,
JUP,
PSMC3,
NFKB1,
PSMB1,
FGFR2,
PSMA1,
PSMA2,
PSMA3,
PSMA4,
PSMB8,
PSMB9,
PSMB4,
PSMB5,
FGF9,
PSMC2,
PSMB10,
PSMC4,
YAP1,
CSNK1D,
CSNK1E,
PSMB3,
PSMD7,
DLX5,
PSME3,
PSMC1,
PSMC6,
RPS27A,
UBA52,
XIAP,
CAV1,
SOX4,
BAMBI,
PSMD2,
ILK,
PSME4,
DIXDC1,
WLS,
TMEM198,
SFRP4,
USP34,
SULF2,
ASPM,
CCAR2,
SFRP1,
TRPM4,
WNT2B,
ZBED3,
VPS35,
LGR4,
RSPO3,
TNKS2,
SMURF2,
LGR6,
RNF146,
GPRC5B,
DKK2
|
|
GO:0090265
|
BP
|
positive regulation of immune complex clearance by monocytes and macrophages
|
Any process that increases the rate, frequency, or extent of the process of immune complex clearance by monocytes or macrophages.
|
CCL2
|
|
GO:0090266
|
BP
|
regulation of mitotic cell cycle spindle assembly checkpoint
|
Any process that modulates the rate, frequency, or extent of the mitotic cell cycle spindle assembly checkpoint, a cell cycle checkpoint that delays the metaphase/anaphase transition of a mitotic nuclear division until the spindle is correctly assembled and chromosomes are attached to the spindle.
|
CCNB1,
DUSP1,
USP44,
LCMT1
|
|
GO:0090267
|
BP
|
positive regulation of mitotic cell cycle spindle assembly checkpoint
|
Any process that increases the rate, frequency, or extent of the mitotic cell cycle spindle assembly checkpoint, a cell cycle checkpoint that delays the metaphase/anaphase transition of a mitotic nuclear division until the spindle is correctly assembled and chromosomes are attached to the spindle.
|
NDC80,
TPR,
MAD2L1
|