Search Geneontologies

Geneontologies

GO ID Ontology GO Term Term Definition Proteins

GO:1901534

BP

positive regulation of hematopoietic progenitor cell differentiation

Any process that activates or increases the frequency, rate or extent of hematopoietic progenitor cell differentiation.

FOXC1

GO:1901536

BP

negative regulation of DNA demethylation

Any process that stops, prevents or reduces the frequency, rate or extent of DNA demethylation.

TRIM28

GO:1901558

BP

response to metformin

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a metformin stimulus.

PPARG, PPARGC1A

GO:1901581

BP

negative regulation of telomeric RNA transcription from RNA pol II promoter

Any process that stops, prevents or reduces the frequency, rate or extent of telomeric RNA transcription from RNA pol II promoter.

ATRX

GO:1901582

BP

positive regulation of telomeric RNA transcription from RNA pol II promoter

Any process that activates or increases the frequency, rate or extent of telomeric RNA transcription from RNA pol II promoter.

ATRX

GO:1901585

BP

regulation of acid-sensing ion channel activity

Any process that modulates the frequency, rate or extent of acid-sensing ion channel activity.

STOM

GO:1901594

BP

response to capsazepine

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a capsazepine stimulus.

TRPV1

GO:1901620

BP

regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning

Any process that modulates the frequency, rate or extent of smoothened signaling pathway involved in dorsal/ventral neural tube patterning.

MKS1

GO:1901621

BP

negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning

Any process that stops, prevents or reduces the frequency, rate or extent of smoothened signaling pathway involved in dorsal/ventral neural tube patterning.

TULP3, PRKACA, SUFU

GO:1901628

BP

positive regulation of postsynaptic membrane organization

Any process that activates or increases the frequency, rate or extent of postsynaptic membrane organization.

APOE

GO:1901630

BP

negative regulation of presynaptic membrane organization

Any process that stops, prevents or reduces the frequency, rate or extent of presynaptic membrane organization.

APOE

GO:1901639

BP

XDP catabolic process

The chemical reactions and pathways resulting in the breakdown of XDP.

NUDT16

GO:1901642

BP

nucleoside transmembrane transport

The directed movement of nucleoside across a membrane.

SLC29A1

GO:1901652

BP

response to peptide

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide stimulus.

AVPR2, OXTR

GO:1901653

BP

cellular response to peptide

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide stimulus.

KLF4, AKR1B1, ID1, KLF3, KLF10, KLF15, KLF2

GO:1901657

BP

glycosyl compound metabolic process

The chemical reactions and pathways involving glycosyl compound.

LCT, KL

GO:1901660

BP

calcium ion export

The directed movement of calcium ion out of a cell or organelle.

ATP2B1, ATP2B4

GO:1901661

BP

quinone metabolic process

The chemical reactions and pathways involving quinone.

CRYZL1

GO:1901666

BP

positive regulation of NAD+ ADP-ribosyltransferase activity

Any process that activates or increases the frequency, rate or extent of NAD+ ADP-ribosyltransferase activity.

TGFB1

GO:1901671

BP

positive regulation of superoxide dismutase activity

Any process that activates or increases the frequency, rate or extent of superoxide dismutase activity.

TNF, RGN

GO:1901673

BP

regulation of mitotic spindle assembly

Any process that modulates the frequency, rate or extent of mitotic spindle assembly.

CHMP2A, VPS4B, TPR, PLK1, CHMP4B

GO:1901676

BP

positive regulation of histone H3-K27 acetylation

Any process that activates or increases the frequency, rate or extent of histone H3-K27 acetylation.

LIF

GO:1901687

BP

glutathione derivative biosynthetic process

The chemical reactions and pathways resulting in the formation of glutathione derivative.

MGST3, GSTA4, GSTZ1, GSTA1, GSTP1, GSTM1, MGST1, GSTM3, GSTM2, GSTT1, GSTO1, GSTM4, MGST2, GSTO2, GSTK1

GO:1901723

BP

negative regulation of cell proliferation involved in kidney development

Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation involved in kidney development.

FLCN

GO:1901724

BP

positive regulation of cell proliferation involved in kidney development

Any process that activates or increases the frequency, rate or extent of cell proliferation involved in kidney development.

LIN28A

GO:1901725

BP

regulation of histone deacetylase activity

Any process that modulates the frequency, rate or extent of histone deacetylase activity.

CAMK2D

GO:1901726

BP

negative regulation of histone deacetylase activity

Any process that stops, prevents or reduces the frequency, rate or extent of histone deacetylase activity.

KDM5A

GO:1901727

BP

positive regulation of histone deacetylase activity

Any process that activates or increases the frequency, rate or extent of histone deacetylase activity.

VEGFA, PRKD1, C6orf89, PINK1, PRKD2

GO:1901740

BP

negative regulation of myoblast fusion

Any process that stops, prevents or reduces the frequency, rate or extent of myoblast fusion.

CFLAR

GO:1901741

BP

positive regulation of myoblast fusion

Any process that activates or increases the frequency, rate or extent of myoblast fusion.

FLOT1, CD53, IL4R, NFATC2, MAPK14, GDF15

GO:1901796

BP

regulation of signal transduction by p53 class mediator

Any process that modulates the frequency, rate or extent of signal transduction by p53 class mediator.

CHEK1, AURKA, MDM4, NUAK1, RAD1, NBN, MBD3, TP53, UBC, CDK2, AKT1, RPA3, RFC4, RFC2, BRCA1, RFC5, RFC3, MRE11A, DNA2, BLM, PRKAG1, PRKAA2, RPS27A, UBA52, CDK5, MDM2, SSRP1, RBBP4, EP300, TAF10, HDAC1, TP53BP2, CHD4, TAF5, TAF11, STK11, TAF12, MAPK14, RAD9B, JMY, BANP, SETD9, PPP1R13L, ATRIP, TOPBP1, DYRK2, HDAC2, KAT6A, RAD50, TP53INP1, AURKB, EHMT2, TP53RK, RAD9A, BARD1, RHNO1, PHF20, HIPK2, MEAF6, TAF9B, BRD7, KMT5A, PRKAG3, TPX2, EXO1, NOC2L, L3MBTL1, SUPT16H

GO:1901797

BP

negative regulation of signal transduction by p53 class mediator

Any process that stops, prevents or reduces the frequency, rate or extent of signal transduction by p53 class mediator.

MDM2, RFFL

GO:1901798

BP

positive regulation of signal transduction by p53 class mediator

Any process that activates or increases the frequency, rate or extent of signal transduction by p53 class mediator.

HEXIM1

GO:1901799

BP

negative regulation of proteasomal protein catabolic process

Any process that stops, prevents or reduces the frequency, rate or extent of proteasomal protein catabolic process.

GABARAPL2, LAMP3

GO:1901800

BP

positive regulation of proteasomal protein catabolic process

Any process that activates or increases the frequency, rate or extent of proteasomal protein catabolic process.

PARK2, XBP1, PSMC3, PSMC2, PSMC4, PSMC1, PSMC6, FMR1

GO:1901835

BP

positive regulation of deadenylation-independent decapping of nuclear-transcribed mRNA

Any process that activates or increases the frequency, rate or extent of deadenylation-independent decapping of nuclear-transcribed mRNA.

ZFP36

GO:1901837

BP

negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter

Any process that stops, prevents or reduces the frequency, rate or extent of transcription of nuclear large rRNA transcript from RNA polymerase I promoter.

H2AFY, H2AFY2

GO:1901838

BP

positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter

Any process that activates or increases the frequency, rate or extent of transcription of nuclear large rRNA transcript from RNA polymerase I promoter.

SMARCA4, NOL11

GO:1901841

BP

regulation of high voltage-gated calcium channel activity

Any process that modulates the frequency, rate or extent of high voltage-gated calcium channel activity.

SRI, CALM2

GO:1901843

BP

positive regulation of high voltage-gated calcium channel activity

Any process that activates or increases the frequency, rate or extent of high voltage-gated calcium channel activity.

CACNA2D1, FGF14

GO:1901844

BP

regulation of cell communication by electrical coupling involved in cardiac conduction

Any process that modulates the frequency, rate or extent of cell communication by electrical coupling involved in cardiac conduction.

SRI, CALM2, CAV1, PDE4D, CAMK2D

GO:1901856

BP

negative regulation of cellular respiration

Any process that stops, prevents or reduces the frequency, rate or extent of cellular respiration.

FLCN

GO:1901857

BP

positive regulation of cellular respiration

Any process that activates or increases the frequency, rate or extent of cellular respiration.

PPARGC1A, PRELID1

GO:1901859

BP

negative regulation of mitochondrial DNA metabolic process

Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial DNA metabolic process.

FLCN

GO:1901860

BP

positive regulation of mitochondrial DNA metabolic process

Any process that activates or increases the frequency, rate or extent of mitochondrial DNA metabolic process.

PPARGC1A

GO:1901862

BP

negative regulation of muscle tissue development

Any process that stops, prevents or reduces the frequency, rate or extent of muscle tissue development.

IGFBP5, FLCN

GO:1901863

BP

positive regulation of muscle tissue development

Any process that activates or increases the frequency, rate or extent of muscle tissue development.

PPARGC1A

GO:1901874

BP

negative regulation of post-translational protein modification

Any process that stops, prevents or reduces the frequency, rate or extent of post-translational protein modification.

CRTAP, FLCN

GO:1901877

BP

negative regulation of calcium ion binding

Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion binding.

PLN

GO:1901888

BP

regulation of cell junction assembly

Any process that modulates the frequency, rate or extent of cell junction assembly.

RAP1A, RAPGEF1

GO:1901890

BP

positive regulation of cell junction assembly

Any process that activates or increases the frequency, rate or extent of cell junction assembly.

FLOT1

GO:1901894

BP

regulation of calcium-transporting ATPase activity

Any process that modulates the frequency, rate or extent of calcium-transporting ATPase activity.

PLN

GO:1901895

BP

negative regulation of calcium-transporting ATPase activity

Any process that stops, prevents or reduces the frequency, rate or extent of calcium-transporting ATPase activity.

PLN

GO:1901896

BP

positive regulation of calcium-transporting ATPase activity

Any process that activates or increases the frequency, rate or extent of calcium-transporting ATPase activity.

RGN, RYR2

GO:1901897

BP

regulation of relaxation of cardiac muscle

Any process that modulates the frequency, rate or extent of relaxation of cardiac muscle.

PLN, CAMK2D

GO:1901898

BP

negative regulation of relaxation of cardiac muscle

Any process that stops, prevents or reduces the frequency, rate or extent of relaxation of cardiac muscle.

PDE4D

GO:1901907

BP

diadenosine pentaphosphate catabolic process

The chemical reactions and pathways resulting in the breakdown of diadenosine pentaphosphate.

NUDT3, NUDT10, NUDT11

GO:1901909

BP

diadenosine hexaphosphate catabolic process

The chemical reactions and pathways resulting in the breakdown of diadenosine hexaphosphate.

NUDT3, NUDT10, NUDT11

GO:1901911

BP

adenosine 5'-(hexahydrogen pentaphosphate) catabolic process

The chemical reactions and pathways resulting in the breakdown of adenosine 5'-(hexahydrogen pentaphosphate).

NUDT3, NUDT10, NUDT11

GO:1901962

BP

S-adenosyl-L-methionine transmembrane transport

The directed movement of S-adenosyl-L-methionine across a membrane.

SLC25A26

GO:1901964

BP

positive regulation of cell proliferation involved in outflow tract morphogenesis

Any process that activates or increases the frequency, rate or extent of cell proliferation involved in outflow tract morphogenesis.

BMP4

GO:1901970

BP

positive regulation of mitotic sister chromatid separation

Any process that activates or increases the frequency, rate or extent of mitotic sister chromatid separation.

ESPL1

GO:1901976

BP

regulation of cell cycle checkpoint

Any process that modulates the frequency, rate or extent of cell cycle checkpoint.

AKT1

GO:1901978

BP

positive regulation of cell cycle checkpoint

Any process that activates or increases the frequency, rate or extent of cell cycle checkpoint.

PROX1

GO:1901979

BP

regulation of inward rectifier potassium channel activity

Any process that modulates the frequency, rate or extent of inward rectifier potassium channel activity.

CAV1

GO:1901985

BP

positive regulation of protein acetylation

Any process that activates or increases the frequency, rate or extent of protein acetylation.

CAMK1

GO:1901989

BP

positive regulation of cell cycle phase transition

Any process that activates or increases the frequency, rate or extent of cell cycle phase transition.

CDCA5

GO:1901990

BP

regulation of mitotic cell cycle phase transition

Any process that modulates the frequency, rate or extent of mitotic cell cycle phase transition.

ERCC2, XPC, NEK11

GO:1901991

BP

negative regulation of mitotic cell cycle phase transition

Any process that stops, prevents or reduces the frequency, rate or extent of mitotic cell cycle phase transition.

ZFP36L2, ZFP36L1, TPRA1, RGCC

GO:1901998

BP

toxin transport

The directed movement of a toxin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

ARID1A, NRP1, LRP6, SLC22A3, HSPA5, TCP1, CASP1, DNAJA1, CCT3, CCT8, RAB28, ANTXR2, COPZ1, CCT2, BNIP3, ATP6V0A1, CCT7, SLC7A8, GGA1

GO:1902003

BP

regulation of beta-amyloid formation

Any process that modulates the frequency, rate or extent of beta-amyloid formation.

TMED10

GO:1902004

BP

positive regulation of beta-amyloid formation

Any process that activates or increases the frequency, rate or extent of beta-amyloid formation.

GSAP, CLU, CSNK1E, PICALM

GO:1902010

BP

negative regulation of translation in response to endoplasmic reticulum stress

Any process that stops, prevents, or reduces the frequency, rate or extent of translation as a result of endoplasmic reticulum stress.

SESN2

GO:1902017

BP

regulation of cilium assembly

Any process that modulates the frequency, rate or extent of cilium assembly.

CYLD, DCDC2, VDAC3

GO:1902018

BP

negative regulation of cilium assembly

Any process that stops, prevents or reduces the frequency, rate or extent of cilium assembly.

EVI5L

GO:1902031

BP

regulation of NADP metabolic process

Any process that modulates the frequency, rate or extent of NADP metabolic process.

ME2

GO:1902033

BP

regulation of hematopoietic stem cell proliferation

Any process that modulates the frequency, rate or extent of hematopoietic stem cell proliferation.

ACE

GO:1902035

BP

positive regulation of hematopoietic stem cell proliferation

Any process that activates or increases the frequency, rate or extent of hematopoietic stem cell proliferation.

KITLG, PDCD2, N4BP2L2

GO:1902037

BP

negative regulation of hematopoietic stem cell differentiation

Any process that stops, prevents or reduces the frequency, rate or extent of hematopoietic stem cell differentiation.

N4BP2L2

GO:1902038

BP

positive regulation of hematopoietic stem cell differentiation

Any process that activates or increases the frequency, rate or extent of hematopoietic stem cell differentiation.

FOXC1

GO:1902041

BP

regulation of extrinsic apoptotic signaling pathway via death domain receptors

Any process that modulates the frequency, rate or extent of extrinsic apoptotic signaling pathway via death domain receptors.

CFLAR, LGALS3, SP100, FAS, TNFSF10, STX4, FADD, RIPK1, CASP8, TRADD, FEM1B

GO:1902042

BP

negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

Any process that stops, prevents or reduces the frequency, rate or extent of extrinsic apoptotic signaling pathway via death domain receptors.

CFLAR, FGA, FGB, FGG, RAF1, SERPINE1, ICAM1, GPX1, HMOX1, HGF, TNFAIP3, FAS, HMGB2, NOS3, BRCA1, TNFSF10, DAPK1, FADD, RIPK1, CASP8, PEA15, TRADD, RFFL, ARHGEF2, TMBIM1

GO:1902043

BP

positive regulation of extrinsic apoptotic signaling pathway via death domain receptors

Any process that activates or increases the frequency, rate or extent of extrinsic apoptotic signaling pathway via death domain receptors.

THBS1, SKIL, MAL, STK4, FADD, PMAIP1, PEA15, SFRP1, FAF1

GO:1902044

BP

regulation of Fas signaling pathway

Any process that modulates the frequency, rate or extent of Fas signaling pathway.

SP100

GO:1902045

BP

negative regulation of Fas signaling pathway

Any process that stops, prevents or reduces the frequency, rate or extent of Fas signaling pathway.

TMBIM1

GO:1902065

BP

response to L-glutamate

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an L-glutamate stimulus.

AIFM1, PCNA, CREB1

GO:1902068

BP

regulation of sphingolipid mediated signaling pathway

Any process that modulates the frequency, rate or extent of sphingolipid signaling.

PLPP3

GO:1902074

BP

response to salt

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a salt stimulus.

EDN1, HRSP12

GO:1902081

BP

negative regulation of calcium ion import into sarcoplasmic reticulum

Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion import into sarcoplasmic reticulum.

PLN

GO:1902083

BP

negative regulation of peptidyl-cysteine S-nitrosylation

Any process that stops, prevents or reduces the frequency, rate or extent of peptidyl-cysteine S-nitrosylation.

DMD, ATP2B4, SNTA1

GO:1902108

BP

regulation of mitochondrial membrane permeability involved in apoptotic process

Any regulation of mitochondrial membrane permeability that is involved in apoptotic process.

THEM4

GO:1902109

BP

negative regulation of mitochondrial membrane permeability involved in apoptotic process

Any negative regulation of mitochondrial membrane permeability that is involved in apoptotic process.

NOL3

GO:1902115

BP

regulation of organelle assembly

Any process that modulates the frequency, rate or extent of organelle assembly.

EZR, RDX

GO:1902161

BP

positive regulation of cyclic nucleotide-gated ion channel activity

Any process that activates or increases the frequency, rate or extent of cyclic nucleotide-gated ion channel activity.

CFTR

GO:1902166

BP

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator.

TRIAP1, KDM1A, CD74, MIF, MUC1, CD44, BCL2L12, TAF9B

GO:1902170

BP

cellular response to reactive nitrogen species

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reactive nitrogen species stimulus.

MAP3K5

GO:1902172

BP

regulation of keratinocyte apoptotic process

Any process that modulates the frequency, rate or extent of keratinocyte apoptotic process.

ZFP36, ZFP36L1

GO:1902173

BP

negative regulation of keratinocyte apoptotic process

Any process that stops, prevents or reduces the frequency, rate or extent of keratinocyte apoptotic process.

SERPINB13

GO:1902174

BP

positive regulation of keratinocyte apoptotic process

Any process that activates or increases the frequency, rate or extent of keratinocyte apoptotic process.

SFRP4

GO:1902175

BP

regulation of oxidative stress-induced intrinsic apoptotic signaling pathway

Any process that modulates the frequency, rate or extent of an oxidative stress-induced intrinsic apoptotic signaling pathway.

P4HB