GO:0050776

BP

regulation of immune response

Any process that modulates the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.

TYROBP, C3, HLA-B, COL1A1, COL3A1, ITGB2, ICAM1, ITGB1, COL1A2, FCGR1A, IFITM1, HLA-E, SELL, PVR, CD1D, HLA-G, VCAM1, CD33, KLRC1, CD40LG, HLA-A, HLA-F, FCGR2B, BCL6, CD200, KIR3DL2, CD81, B2M, CXADR, SMAD3, MICB, MICA, CD276, LAIR1, LAIR2, LILRB1, SPPL2A, CLEC2B, ULBP3, TREM1, COL17A1, SIGLEC7

GO:0050777

BP

negative regulation of immune response

Any process that stops, prevents, or reduces the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.

COL3A1, AMBP, LYN, HLA-G, TGFB2, INPP5D, FOXP3

GO:0050778

BP

positive regulation of immune response

Any process that activates or increases the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.

TGFB2

GO:0050779

BP

RNA destabilization

Any process that decreases the stability of an RNA molecule, making it more vulnerable to degradative processes.

DXO, TNFRSF1B

GO:0050790

BP

regulation of catalytic activity

Any process that modulates the activity of an enzyme.

KRIT1, ZEB2, BAG2, CTSB, AR, CAPN3, BRCC3, RCAN1, GPSM2, RING1, DMPK, SEPT2, PPP1R7, PPP1R3B, ANKLE2, GPSM1, PCP2, TTN, MTMR9, GRPEL1, GOPC, BMP2K, MAT2B, SH3BP4, ATP6V1H, GPSM3

GO:0050792

BP

regulation of viral process

Any process that modulates the rate or extent of the viral life cycle, the set of processes by which a virus reproduces and spreads among hosts.

CHMP2A, VPS4B, CHMP4B

GO:0050793

BP

regulation of developmental process

Any process that modulates the frequency, rate or extent of development, the biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).

NOTCH2

GO:0050794

BP

regulation of cellular process

Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

WNK1

GO:0050795

BP

regulation of behavior

Any process that modulates the frequency, rate or extent of behavior, the internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal or external stimuli.

MDK, HTR2B, HOXA1, AHI1

GO:0050796

BP

regulation of insulin secretion

Any process that modulates the frequency, rate or extent of the regulated release of insulin.

ARNTL, ENSA, GCG, TNF, IL1B, SLC25A5, SLC2A1, SLC25A4, CCL5, PRKCA, CNR1, MARCKS, SSTR5, LEP, MTNR1B, CPT1A, SNAP25, RAP1A, ICA1, CACNA1C, ITPR2, ITPR3, ITPR1, KCNJ11, CACNA1E, CARTPT, RAPGEF4, UQCC2

GO:0050798

BP

activated T cell proliferation

The expansion of a T cell population following activation by an antigenic stimulus.

FYN, SATB1

GO:0050801

BP

ion homeostasis

Any process involved in the maintenance of an internal steady state of ions within an organism or cell.

KLHL3

GO:0050803

BP

regulation of synapse structure or activity

Any process that modulates the physical form or the activity of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell).

APP, PPT1, SYNGAP1

GO:0050804

BP

modulation of synaptic transmission

Any process that modulates the frequency or amplitude of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse. Amplitude, in this case, refers to the change in postsynaptic membrane potential due to a single instance of synaptic transmission.

CSPG5, PRKACA, HRH1, PPP3CA, EIF4EBP2, PXK, BTBD9

GO:0050805

BP

negative regulation of synaptic transmission

Any process that stops, prevents, or reduces the frequency, rate or extent of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse.

PCDH17, GNAI2, GNAI1, ADIPOQ, TNR

GO:0050806

BP

positive regulation of synaptic transmission

Any process that activates or increases the frequency, rate or extent of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse.

CLSTN1, CCL2, SYT1, SLC1A3, NMU, DLG4, KISS1, CLSTN2, RETN

GO:0050807

BP

regulation of synapse organization

Any process that modulates the physical form of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell).

DKK1, IL10, ETV5

GO:0050808

BP

synapse organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell).

SEMA3E, PAK3, CTNNB1, SNCA, LRRTM4, NLGN4X, SLC9A6, TNR, RAB39B, PCDHGC3, MYO5A

GO:0050810

BP

regulation of steroid biosynthetic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus.

DHH, TSPO, LEP, IGFBP7, DDX20

GO:0050812

BP

regulation of acyl-CoA biosynthetic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of acyl-CoA.

SNCA

GO:0050819

BP

negative regulation of coagulation

Any process that stops, prevents, or reduces the frequency, rate or extent of coagulation.

ANXA5, PROCR

GO:0050820

BP

positive regulation of coagulation

Any process that activates or increases the frequency, rate or extent of coagulation.

PSEN1

GO:0050821

BP

protein stabilization

Any process involved in maintaining the structure and integrity of a protein and preventing it from degradation or aggregation.

USP27X, PLPP3, SMAD7, MDM4, ZNF207, PARK2, CREBL2, USP2, CRTAP, WIZ, APOA1, GAPDH, IGF1, ATP1B1, PFN1, HSP90AA1, HSP90AB1, HSPA1A, HSPA1B, HSPD1, CLU, LAMP1, LAMP2, CREB1, TCP1, FLNA, PPIB, MT3, CALR, PIK3R1, PHB, CDKN1A, CCT6A, CCT3, GNAQ, CCT8, ATP1B3, PTEN, STXBP1, UBE2B, CCT2, SMAD3, ANK2, PRKCD, SOX4, EP300, STK4, MORC3, CDC37, AAK1, TBRG1, SYVN1, USP13, ZBED3, PHB2, CHP1, CCT7, PDCD10, NAA15, PINK1, SOX17, TAF9B, IFT46, HPS4, GTSE1, NLK, PPARGC1A, SEL1L

GO:0050829

BP

defense response to Gram-negative bacterium

Reactions triggered in response to the presence of a Gram-negative bacterium that act to protect the cell or organism.

TLR4, TLR5, LYZL6, CD4, APP, SERPINE1, IL6, IL6R, DEFA4, HMGB2, S100A7, ADM, SLC11A1, LYZ, B2M, FCN2, MR1, OPTN, PYCARD

GO:0050830

BP

defense response to Gram-positive bacterium

Reactions triggered in response to the presence of a Gram-positive bacterium that act to protect the cell or organism.

RIPK2, TLR2, HIST1H2BK, LYZL6, TNF, CRP, ANG, APP, IL6, FGR, MBL2, DEFA4, HLA-E, PLA2G2A, CD36, C5AR1, HMGB2, IL12A, ADM, TIRAP, LYZ, B2M, HIST1H2BC, ADAM17, FCN2, HIST2H2BE, SEH1L, PGLYRP2, TBK1

GO:0050832

BP

defense response to fungus

Reactions triggered in response to the presence of a fungus that act to protect the cell or organism.

S100A8, MPO, S100A9, DEFA4, HAMP, COTL1, SPON2

GO:0050847

BP

progesterone receptor signaling pathway

Any series of molecular signals generated as a consequence of a progesterone binding to its receptor.

UBR5, PHB

GO:0050848

BP

regulation of calcium-mediated signaling

Any process that modulates the frequency, rate or extent of calcium-mediated signaling, the process in which a cell uses calcium ions to convert an extracellular signal into a response.

GBP1, RGN

GO:0050849

BP

negative regulation of calcium-mediated signaling

Any process that stops, prevents, or reduces the frequency, rate or extent of calcium-mediated signaling.

ITPR1

GO:0050850

BP

positive regulation of calcium-mediated signaling

Any process that activates or increases the frequency, rate or extent of calcium-mediated signaling.

ADA, CD4, CCL3, CCL4, SYK, HINT1, CDH13, P2RX4

GO:0050851

BP

antigen receptor-mediated signaling pathway

A series of molecular signals initiated by the cross-linking of an antigen receptor on a B or T cell.

RFTN2

GO:0050852

BP

T cell receptor signaling pathway

A series of molecular signals initiated by the cross-linking of an antigen receptor on a T cell.

PSMD11, PSMD12, PIK3CD, FYB, PSMD3, MAP3K7, RIPK2, TNFRSF21, PSMD10, PAK3, BCL10, CD4, HLA-DRA, HLA-DQA2, HLA-DQA1, HLA-DQB1, FYN, PTPRC, UBC, CD28, HLA-DRB4, PLCG2, PSMC3, NFKB1, HLA-DPA1, PSMB1, PSMA1, PSMA2, PSMA3, PSMA4, PIK3R1, PSMB8, PSMB9, PSMB4, PSMB5, MAPK1, PSMC2, PSMB10, CSK, PIK3CA, PIK3CB, PSMC4, PSMB3, PSEN1, PSMD7, CACNB3, PTEN, PSME3, PSMC1, PSMC6, RPS27A, UBA52, SKP1, HLA-DRB3, RELA, PRKCQ, PDE4D, PTPRJ, PAK2, PSMD2, UBE2V1, RFTN1, PSME4, SHB, STK11, HLA-DRB5, THEMIS2, SPPL3, INPP5D, PRKD2, FOXP3, PAG1, BTRC

GO:0050853

BP

B cell receptor signaling pathway

A series of molecular signals initiated by the cross-linking of an antigen receptor on a B cell.

IGLL5, PIK3CD, PRKCB, LYN, PTPRC, BCL2, PLCG2, MAPK1, MNDA, SYK, MEF2C, NFATC2, RFTN1, KLHL6, VAV3

GO:0050855

BP

regulation of B cell receptor signaling pathway

Any process that modulates the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B cell.

LYN, PTPN22

GO:0050856

BP

regulation of T cell receptor signaling pathway

Any process that modulates the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a T cell.

BCL10

GO:0050857

BP

positive regulation of antigen receptor-mediated signaling pathway

Any process that activates or increases the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B- or T cell.

PTPRC

GO:0050859

BP

negative regulation of B cell receptor signaling pathway

Any process that stops, prevents, or reduces the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B cell.

LPXN, PLCL2

GO:0050860

BP

negative regulation of T cell receptor signaling pathway

Any process that stops, prevents, or reduces the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a T cell.

PRNP, EZR, PTPN2, LGALS3, GBP1, DUSP3, PTPRJ, PAWR, DUSP22, PHPT1, PTPN22

GO:0050861

BP

positive regulation of B cell receptor signaling pathway

Any process that activates or increases the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B cell.

PRKCB, LYN, CMTM3, SLC39A10

GO:0050862

BP

positive regulation of T cell receptor signaling pathway

Any process that activates or increases the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a T cell.

RAB29, ADA, PRKD2

GO:0050863

BP

regulation of T cell activation

Any process that modulates the frequency, rate or extent of T cell activation.

CD4, CCL5, PAG1

GO:0050865

BP

regulation of cell activation

Any process that modulates the frequency, rate or extent of cell activation, the change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand.

LMO4

GO:0050867

BP

positive regulation of cell activation

Any process that activates or increases the frequency, rate or extent of activation.

JAK2, CTGF

GO:0050868

BP

negative regulation of T cell activation

Any process that stops, prevents, or reduces the frequency, rate or extent of T cell activation.

SOCS6, LAG3, DUSP3, JAK3, VTCN1, DUSP22, PAG1, PTPN22

GO:0050869

BP

negative regulation of B cell activation

Any process that stops, prevents, or reduces the frequency, rate or extent of B cell activation.

TNFAIP3, FAS, SAMSN1

GO:0050870

BP

positive regulation of T cell activation

Any process that activates or increases the frequency, rate or extent of T cell activation.

TNFSF11, MAP3K7, BCL10, HSPD1, CCL2, HLA-DPA1, PRKCQ, CD47, PYCARD

GO:0050871

BP

positive regulation of B cell activation

Any process that activates or increases the frequency, rate or extent of B cell activation.

IGLL5, IL6, TNFSF4

GO:0050872

BP

white fat cell differentiation

The process in which a relatively unspecialized cell acquires specialized features of a white adipocyte, an animal connective tissue cell involved in energy storage. White adipocytes have cytoplasmic lipids arranged in a unique vacuole.

SNAI2, FABP4, PPARG, CTBP2, AACS, TBL1XR1

GO:0050873

BP

brown fat cell differentiation

The process in which a relatively unspecialized cell acquires specialized features of a brown adipocyte, an animal connective tissue cell involved in adaptive thermogenesis. Brown adipocytes contain multiple small droplets of triglycerides and a high number of mitochondria.

LRG1, ADRB2, ADRB1, NUDT7, ADRB3, SLC2A4, FABP4, CEBPB, ITGA6, UCP1, PTGS2, RGS2, ALDH6A1, BNIP3, ADIPOQ, MRAP, ERO1A, RARRES2, EBF2, PPARGC1A

GO:0050877

BP

neurological system process

A organ system process carried out by any of the organs or tissues of neurological system.

CHRNB1, KCNJ11, GPR98

GO:0050878

BP

regulation of body fluid levels

Any process that modulates the levels of body fluids.

EPHB2, PDSS2, HEG1

GO:0050880

BP

regulation of blood vessel size

Any process that modulates the size of blood vessels.

ITGB1BP1, NOS3, NTS, GCLC, GCLM, HBB, FOXC1

GO:0050881

BP

musculoskeletal movement

The movement of an organism or part of an organism using mechanoreceptors, the nervous system, striated muscle and/or the skeletal system.

GIGYF2

GO:0050882

BP

voluntary musculoskeletal movement

The movement of an organism or part of an organism using mechanoreceptors, the nervous system, striated muscle and/or the skeletal system that can be controlled at will.

ITPR1, HIPK2

GO:0050883

BP

musculoskeletal movement, spinal reflex action

Involuntary movement caused by the application of a stimulus to an organism and a subsequent movement. The signal processing of this movement takes place in the spinal cord.

ASCL1

GO:0050884

BP

neuromuscular process controlling posture

Any process in which an organism voluntarily modulates its posture, the alignment of its anatomical parts.

GAA, TCF15, PNKD

GO:0050885

BP

neuromuscular process controlling balance

Any process that an organism uses to control its balance, the orientation of the organism (or the head of the organism) in relation to the source of gravity. In humans and animals, balance is perceived through visual cues, the labyrinth system of the inner ears and information from skin pressure receptors and muscle and joint receptors.

TPP1, RBFOX2, NBN, APP, GAA, BCR, GM2A, SLC1A3, ALDH1A3, RAC3, DLG4, ABR, CLN3, GIGYF2, NR4A3, TNR, CLIC5, NRXN1, CAMTA1

GO:0050890

BP

cognition

The operation of the mind by which an organism becomes aware of objects of thought or perception; it includes the mental activities associated with thinking, learning, and memory.

SOBP, CHL1, HLA-DRA, LHCGR, ADORA1, CHRNA7, SLC1A4, HOXA1, GNAS, ST3GAL4, GNAS, NIPBL, CYFIP1, LINS1, RP9, PTCHD1, CHD7, GTF2A1L, HRH3

GO:0050891

BP

multicellular organismal water homeostasis

Any process involved in the maintenance of an internal steady state of water within a tissue, organ, or a multicellular organism.

SCNN1A, SCNN1G, TRPV4

GO:0050892

BP

intestinal absorption

Any process in which nutrients are taken up from the contents of the intestine.

VDR, CD36, LEP, SCARB1, TJP2, F11R

GO:0050893

BP

sensory processing

Any neural process required for an organism to sense and interpret the dimensions of a sensory experience: modality, location, intensity and affect.

TTC8

GO:0050896

BP

response to stimulus

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism.

PDE6D, MIP, SCNN1A, PPT1, SCNN1G, TGFBI, FAM161A, CYP4V2, ZNF513, BBS1, WDR36, BBS10, RPGR, HPS1, SPATA7, SLC45A2

GO:0050900

BP

leukocyte migration

The movement of a leukocyte within or between different tissues and organs of the body.

ANGPT2, SLC16A3, GPR32, F2, NRAS, KRAS, COL1A1, FN1, MMP1, APOB, CD74, ATP1B1, ITGB3, ITGB2, ICAM1, ITGB1, FYN, ITGAV, LYN, COL1A2, SLC3A2, ITGA5, CD48, ITGAM, SELL, MIF, MMP9, B4GALT1, CD44, PECAM1, SELE, CD58, ITGAX, MAG, FPR1, C5AR1, ITGA6, FPR2, ITGA3, PIK3R1, MYH9, BSG, PIK3CA, PIK3CB, ATP1B3, F2RL1, JAM2, PPIA, GRB2, CXADR, SIRPA, OLR1, SLC7A9, SLC7A5, TEK, CAV1, PTPN11, SOS1, CD47, MERTK, PPIL2, SELPLG, GAS6, GRB14, ANGPT1, CD177, SLC7A6, INPP5D, GLG1, JAM3, CD244, TREM1, SLC7A8, SLC7A7, PROCR, SLC7A11, F11R

GO:0050901

BP

leukocyte tethering or rolling

Transient adhesive interactions between leukocytes and endothelial cells lining blood vessels. Carbohydrates on circulating leukocytes bind selectins on the vessel wall causing the leukocytes to slow down and roll along the inner surface of the vessel wall. During this rolling motion, transitory bonds are formed and broken between selectins and their ligands. Typically the first step in cellular extravasation (the movement of leukocytes out of the circulatory system, towards the site of tissue damage or infection).

TNF, ITGB1, SELE, VCAM1, LEP

GO:0050902

BP

leukocyte adhesive activation

The activation of loosely bound or rolling leukocytes by signals displayed on blood vessel endothelial cells, which is typically the second step in cellular extravasation.

SELPLG

GO:0050904

BP

diapedesis

The passage of a leukocyte between the tight junctions of endothelial cells lining blood vessels, typically the fourth and final step of cellular extravasation.

PECAM1

GO:0050905

BP

neuromuscular process

Any process pertaining to the functions of the nervous and muscular systems of an organism.

UCHL1, HOXD10, HOXA1, FGF12, KCNA1, SPG20, AGTPBP1

GO:0050908

BP

detection of light stimulus involved in visual perception

The series of events involved in visual perception in which a light stimulus is received and converted into a molecular signal.

GRM6, BEST1, EYS

GO:0050909

BP

sensory perception of taste

The series of events required for an organism to receive a gustatory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Gustation involves the direct detection of chemical composition, usually through contact with chemoreceptor cells. This is a neurological process.

CD36, SCNN1A, SCNN1G, GNB1

GO:0050910

BP

detection of mechanical stimulus involved in sensory perception of sound

The series of events involved in the perception of sound vibration in which the vibration is received and converted into a molecular signal.

KIT, COL11A1, MKKS

GO:0050911

BP

detection of chemical stimulus involved in sensory perception of smell

The series of events involved in the perception of smell in which an olfactory chemical stimulus is received and converted into a molecular signal.

OR3A3, OR52E8, OR5A2, OR5L2, OR14C36, OR2A5, OR51E2

GO:0050913

BP

sensory perception of bitter taste

The series of events required to receive a bitter taste stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.

ITPR3

GO:0050915

BP

sensory perception of sour taste

The series of events required to receive a sour taste stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.

ASIC2, ASIC3

GO:0050916

BP

sensory perception of sweet taste

The series of events required to receive a sweet taste stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.

ITPR3

GO:0050917

BP

sensory perception of umami taste

The series of events required to receive an umami taste stimulus, convert it to a molecular signal, and recognize and characterize the signal. Umami taste is the savory taste of meats and other foods that are rich in glutamates. This is a neurological process.

ITPR3

GO:0050918

BP

positive chemotaxis

The directed movement of a motile cell or organism towards a higher concentration of a chemical.

NRP1, PDGFB, MET, FGF2, HMGB1, SAA1, SAA2, CCL3, BMP4, CCL5, SCG2, MIF, HGF, VEGFA, LGALS3, FGF7, HMGB2, CORO1A, CXCL12, VEGFC, TSC2, PTPRJ, SEMA5A, ALKBH1, ANGPT1

GO:0050919

BP

negative chemotaxis

The directed movement of a motile cell or organism towards a lower concentration of a chemical.

SEMA3E, FLRT2, SLIT2, SEMA3D, APOA1, PDGFA, ITGB3, ITGAV, PLXNA3, EFNA5, RHOA, SEMA3B, SEMA5A, SEMA3A, SEMA6D, SEMA3C, SEMA6A, SEMA4A, SEMA6B, FLRT3

GO:0050920

BP

regulation of chemotaxis

Any process that modulates the frequency, rate or extent of the directed movement of a motile cell or organism in response to a specific chemical concentration gradient.

PDGFRA, EFNB2, CXCR4

GO:0050921

BP

positive regulation of chemotaxis

Any process that activates or increases the frequency, rate or extent of the directed movement of a motile cell or organism in response to a specific chemical concentration gradient.

PDGFB, TGFB1, THBS1, PDGFRB, PPM1F, F2RL1, STX4, STX3, RARRES2

GO:0050922

BP

negative regulation of chemotaxis

Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a motile cell or organism in response to a specific chemical concentration gradient.

PTPN2

GO:0050925

BP

negative regulation of negative chemotaxis

Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a motile cell or organism towards a lower concentration in a concentration gradient of a specific chemical.

ROBO2

GO:0050927

BP

positive regulation of positive chemotaxis

Any process that activates or increases the frequency, rate or extent of the directed movement of a motile cell or organism towards a higher concentration in a concentration gradient of a specific chemical.

VEGFA, ITGA2, S1PR1, F2RL1, CDH13, SMAD3

GO:0050928

BP

negative regulation of positive chemotaxis

Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a motile cell or organism towards a higher concentration in a concentration gradient of a specific chemical.

ANGPT2

GO:0050929

BP

induction of negative chemotaxis

Any process that initiates the directed movement of a motile cell or organism towards a lower concentration in a concentration gradient of a specific chemical.

SLIT2

GO:0050930

BP

induction of positive chemotaxis

Any process that initiates the directed movement of a motile cell or organism towards a higher concentration in a concentration gradient of a specific chemical.

CXCL8, SCG2, VEGFA, CXCL12, PGF, VEGFC

GO:0050942

BP

positive regulation of pigment cell differentiation

Any process that activates or increases the frequency, rate or extent of pigment cell differentiation.

BLOC1S6

GO:0050951

BP

sensory perception of temperature stimulus

The series of events required for an organism to receive a sensory temperature stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.

BTBD9

GO:0050953

BP

sensory perception of light stimulus

The series of events required for an organism to receive a sensory light stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.

GPR98

GO:0050954

BP

sensory perception of mechanical stimulus

The series of events required for an organism to receive a sensory mechanical stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.

TRPV1

GO:0050955

BP

thermoception

The series of events required for an organism to receive a temperature stimulus, convert it to a molecular signal, and recognize and characterize the signal. Thermoception in larger animals is mainly done in the skin; mammals have at least two types of sensor, for detecting heat (temperatures above body temperature) and cold (temperatures below body temperature).

TRPV1

GO:0050960

BP

detection of temperature stimulus involved in thermoception

The series of events in which a temperature stimulus is received and converted into a molecular signal as part of thermoception.

TRPV1

GO:0050965

BP

detection of temperature stimulus involved in sensory perception of pain

The series of events involved in the perception of pain in which a temperature stimulus is received and converted into a molecular signal.

NTRK1, ADORA1, EPHB1, TRPV1, LXN, ASIC3, MMP24

GO:0050966

BP

detection of mechanical stimulus involved in sensory perception of pain

The series of events involved in the perception of pain in which a mechanical stimulus is received and converted into a molecular signal.

NTRK1, FYN, ITGA2, KCNA1, ASIC3

GO:0050968

BP

detection of chemical stimulus involved in sensory perception of pain

The series of events involved in the perception of pain in which a chemical stimulus is received and converted into a molecular signal.

TRPV1, ASIC3

GO:0050974

BP

detection of mechanical stimulus involved in sensory perception

The series of events in which a mechanical stimulus is received and converted into a molecular signal as part of sensory perception.

SERPINE2, ASIC2

GO:0050976

BP

detection of mechanical stimulus involved in sensory perception of touch

The series of events involved in the perception of touch in which a mechanical stimulus is received and converted into a molecular signal.

KCNA1

GO:0050982

BP

detection of mechanical stimulus

The series of events by which a mechanical stimulus is received and converted into a molecular signal.

JUP, PKD1, PKD2, DENND5A, DENND5B

GO:0050983

BP

deoxyhypusine biosynthetic process from spermidine

The chemical reactions resulting in the formation of deoxyhypusine from spermidine by the enzyme [eIF-5A]-deoxyhypusine synthase. The reaction occurs in four steps: 1. spermidine + NAD+ = dehydrospermidine + NADH + H+; 2. dehydrospermidine + [enzyme]-lysine = 1,3-diaminopropane + [enzyme]-lysine-N6=CH(CH2)3NH2; 3. [enzyme]-lysine-N6=CH(CH2)3NH2 = [eIF-5A]-lysine-N6=CH(CH2)3NH2; 4. [eIF-5A]-lysine-N6=CH(CH2)3NH2 + NADH + H+ = [eIF-5A]-deoxyhypusine + NAD+.

DHPS

GO:0050992

BP

dimethylallyl diphosphate biosynthetic process

The chemical reactions and pathways resulting in the formation of dimethylallyl diphosphate.

IDI1, IDI2

GO:0050994

BP

regulation of lipid catabolic process

Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of lipids.

THRA, LGALS12, RARRES2