GO ID |
Ontology |
GO Term |
Term Definition |
Proteins |
GO:0048026
|
BP
|
positive regulation of mRNA splicing, via spliceosome
|
Any process that activates or increases the rate or extent of mRNA splicing via a spliceosomal mechanism.
|
RBMX,
TRA2B,
DAZAP1,
PRPF19,
THRAP3
|
GO:0048041
|
BP
|
focal adhesion assembly
|
The aggregation and bonding together of a set of components to form a focal adhesion, a complex of intracellular signaling and structural proteins that provides a structural link between the internal actin cytoskeleton and the ECM, and also function as a locus of signal transduction activity.
|
RHOD,
ARHGAP6,
BCL2,
ACTN1,
ITGA2,
ACTN2,
ARHGEF7,
CTTN,
PTPRK,
TRIP6,
AJUBA,
DLC1,
SORBS1,
TAOK2
|
GO:0048048
|
BP
|
embryonic eye morphogenesis
|
The process occurring in the embryo by which the anatomical structures of the post-embryonic eye are generated and organized.
|
AXIN1,
FBN1,
FBN2,
ALDH1A3,
MFAP2,
FOXL2,
EFEMP1
|
GO:0048050
|
BP
|
post-embryonic eye morphogenesis
|
The process, occurring after embryonic development, by which the anatomical structures of the eye are generated and organized. The eye is the organ of sight.
|
FBN1,
MFAP2,
EFEMP1
|
GO:0048066
|
BP
|
developmental pigmentation
|
The developmental process that results in the deposition of coloring matter in an organism, tissue or cell.
|
BCL2L11,
ZEB2,
GNA11,
PMEL,
GNAQ,
SLC45A2
|
GO:0048070
|
BP
|
regulation of developmental pigmentation
|
Any process that modulates the frequency, rate or extent of the developmental process that results in the deposition of coloring matter in an organism.
|
BCL2L11,
KIT
|
GO:0048075
|
BP
|
positive regulation of eye pigmentation
|
Any process that activates or increases the frequency, rate or extent of establishment of a pattern of pigment in the eye of an organism.
|
HPS4
|
GO:0048087
|
BP
|
positive regulation of developmental pigmentation
|
Any process that increases the frequency, rate or extent of the developmental process that results in the deposition of coloring matter in an organism.
|
BAX
|
GO:0048096
|
BP
|
chromatin-mediated maintenance of transcription
|
Maintenance of transcription by remodelling of chromatin into an 'open configuration'. Once established, this regulation is mitotically stable and is maintained over many cell divisions. It is also heritable.
|
ARID1A,
CHEK1,
CTNNB1,
ELOF1,
ARID1B,
SMARCD1,
BAZ1B,
KMT2B
|
GO:0048102
|
BP
|
autophagic cell death
|
A form of programmed cell death that is accompanied by the formation of autophagosomes. Autophagic cell death is characterized by lack of chromatin condensation and massive vacuolization of the cytoplasm, with little or no uptake by phagocytic cells.
|
LAMP1,
CDKN1B,
BNIP3,
TP53INP1,
SH3GLB1
|
GO:0048103
|
BP
|
somatic stem cell division
|
The self-renewing division of a somatic stem cell, a stem cell that can give rise to cell types of the body other than those of the germ-line.
|
FZD7,
KIT,
NOTCH1,
ZFP36L2,
TGFB2
|
GO:0048133
|
BP
|
male germ-line stem cell asymmetric division
|
The self-renewing division of a germline stem cell in the male gonad, to produce a daughter stem cell and a daughter germ cell, which will divide to form the male gametes.
|
ETV5,
ZBTB16
|
GO:0048143
|
BP
|
astrocyte activation
|
A change in morphology and behavior of an astrocyte resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.
|
EGFR,
MT1X
|
GO:0048144
|
BP
|
fibroblast proliferation
|
The multiplication or reproduction of fibroblast cells, resulting in the expansion of the fibroblast population.
|
AGT
|
GO:0048145
|
BP
|
regulation of fibroblast proliferation
|
Any process that modulates the frequency, rate or extent of multiplication or reproduction of fibroblast cells.
|
CREB1,
CTNNB1
|
GO:0048146
|
BP
|
positive regulation of fibroblast proliferation
|
Any process that activates or increases the frequency, rate or extent of multiplication or reproduction of fibroblast cells.
|
EREG,
NDUFS4,
EGFR,
AGT,
MYC,
PDGFB,
TGFB1,
FN1,
ESR1,
PDGFA,
CD74,
IGF1,
JUN,
S100A6,
ANXA2,
WNT2,
PDGFRB,
CDK4,
MIF,
CCNB1,
FOSL2,
PDGFRA,
CCNA2,
BTC,
CDKN1A,
WNT5A,
PRKDC,
CDK6,
E2F1,
GAS6,
RNASEH2B,
WAPL,
CDC6,
PDGFD,
PDGFC,
SPHK1,
ZMIZ1
|
GO:0048147
|
BP
|
negative regulation of fibroblast proliferation
|
Any process that stops, prevents, or reduces the frequency, rate or extent of multiplication or reproduction of fibroblast cells.
|
NUPR1,
MYC,
FTH1,
TP53,
GSTP1,
SKI,
AGTR2,
EMD,
BAX,
PMAIP1,
MORC3,
SFRP1,
PAWR,
DACH1
|
GO:0048148
|
BP
|
behavioral response to cocaine
|
Any process that results in a change in the behavior of an organism as a result of a cocaine stimulus.
|
DRD2,
SNCA,
ABAT,
CDK5,
SDK1,
HOMER1
|
GO:0048149
|
BP
|
behavioral response to ethanol
|
Any process that results in a change in the behavior of an organism as a result of an ethanol stimulus.
|
DRD2,
CHRNA7,
USP46,
EPS8,
HDAC2
|
GO:0048160
|
BP
|
primary follicle stage
|
The stage in oogenesis when a single layer of cuboidal follicle cells surrounds the oocyte. The oocyte nucleus is large.
|
EREG
|
GO:0048167
|
BP
|
regulation of synaptic plasticity
|
A process that modulates synaptic plasticity, the ability of synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers.
|
NCAM1,
ITPKA,
HRH1,
PSEN1,
CDK5,
YWHAH,
MEF2C,
EIF4EBP2,
NFATC4,
CNTN4,
CPEB3,
FGF14,
SYNGAP1,
PLK2,
LZTS1
|
GO:0048168
|
BP
|
regulation of neuronal synaptic plasticity
|
A process that modulates neuronal synaptic plasticity, the ability of neuronal synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers.
|
APOE,
S100B,
EGR2,
STAR,
DBN1,
NSMF,
ARC
|
GO:0048169
|
BP
|
regulation of long-term neuronal synaptic plasticity
|
A process that modulates long-term neuronal synaptic plasticity, the ability of neuronal synapses to change long-term as circumstances require. Long-term neuronal synaptic plasticity generally involves increase or decrease in actual synapse numbers.
|
AGT,
KRAS,
DRD2,
SNCA,
RAB11A,
DLG4,
SYNGAP1
|
GO:0048170
|
BP
|
positive regulation of long-term neuronal synaptic plasticity
|
A process that increases long-term neuronal synaptic plasticity, the ability of neuronal synapses to change long-term as circumstances require. Long-term neuronal synaptic plasticity generally involves increase or decrease in actual synapse numbers.
|
KIT,
EPHB2
|
GO:0048172
|
BP
|
regulation of short-term neuronal synaptic plasticity
|
A process that modulates short-term neuronal synaptic plasticity, the ability of neuronal synapses to change in the short-term as circumstances require. Short-term neuronal synaptic plasticity generally involves increasing or decreasing synaptic sensitivity.
|
RAB3GAP1,
SHISA6
|
GO:0048178
|
BP
|
negative regulation of hepatocyte growth factor biosynthetic process
|
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hepatocyte growth factor.
|
INHBB
|
GO:0048193
|
BP
|
Golgi vesicle transport
|
The directed movement of substances into, out of or within the Golgi apparatus, mediated by vesicles.
|
CYTH3,
STX6,
PRKD1
|
GO:0048194
|
BP
|
Golgi vesicle budding
|
The evagination of the Golgi membrane, resulting in formation of a vesicle.
|
PRKCI
|
GO:0048199
|
BP
|
vesicle targeting, to, from or within Golgi
|
The process in which vesicles are directed to specific destination membranes during transport to, from or within the Golgi apparatus; mediated by the addition of specific coat proteins, including COPI and COPII proteins and clathrin, to the membrane during vesicle formation.
|
TMED10
|
GO:0048203
|
BP
|
vesicle targeting, trans-Golgi to endosome
|
The process in which vesicles are directed to specific destination membranes during transport from the trans-Golgi to the endosome.
|
WIPI1
|
GO:0048205
|
BP
|
COPI coating of Golgi vesicle
|
The addition of COPI proteins and adaptor proteins to Golgi membranes during the formation of transport vesicles, forming a vesicle coat.
|
TMED10,
TMED2,
GBF1
|
GO:0048208
|
BP
|
COPII vesicle coating
|
The addition of COPII proteins and adaptor proteins to ER membranes during the formation of transport vesicles, forming a vesicle coat.
|
PPP6C,
GOSR2,
ANKRD28,
SEC22B,
TRAPPC6A,
SEC24D,
SEC31A,
F8,
SERPINA1,
TGFA,
TRAPPC2,
F5,
FOLR1,
AREG,
NSF,
TRAPPC10,
CSNK1D,
TMED10,
CTSC,
SEC13,
RAB1A,
GOLGA2,
CUL3,
TMED2,
SEC23A,
KLHL12,
TRAPPC5,
MCFD2,
TFG,
SEC16B,
RAB1B,
CTSZ,
PPP6R1,
TRAPPC1,
SAR1B
|
GO:0048211
|
BP
|
Golgi vesicle docking
|
The initial attachment of a Golgi transport vesicle membrane to a target membrane, mediated by proteins protruding from the membrane of the Golgi vesicle and the target membrane.
|
NSF
|
GO:0048227
|
BP
|
plasma membrane to endosome transport
|
Transport of a vesicle from the plasma membrane to the endosome.
|
RAB5C,
RAB5B,
RAB11A,
COMMD1,
USP6NL
|
GO:0048232
|
BP
|
male gamete generation
|
Generation of the male gamete; specialised haploid cells produced by meiosis and along with a female gamete takes part in sexual reproduction.
|
MCM8
|
GO:0048240
|
BP
|
sperm capacitation
|
A process required for sperm to reach fertilization competence. Sperm undergo an incompletely understood series of morphological and molecular maturational processes, termed capacitation, involving, among other processes, protein tyrosine phosphorylation and increased intracellular calcium.
|
DLD,
CFTR,
PRKACA
|
GO:0048241
|
BP
|
epinephrine transport
|
The directed movement of epinephrine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
SLC22A1
|
GO:0048243
|
BP
|
norepinephrine secretion
|
The regulated release of norepinephrine by a cell. Norepinephrine is a catecholamine and it acts as a hormone and as a neurotransmitter of most of the sympathetic nervous system.
|
NISCH
|
GO:0048245
|
BP
|
eosinophil chemotaxis
|
The movement of an eosinophil in response to an external stimulus.
|
CCL3,
CCL5,
SCG2,
LGALS3,
HRH1
|
GO:0048246
|
BP
|
macrophage chemotaxis
|
The movement of a macrophage in response to an external stimulus.
|
SAA1,
CCL3,
CCL2,
CCL5,
LGALS3,
EDN2,
NUP85,
CKLF
|
GO:0048247
|
BP
|
lymphocyte chemotaxis
|
The directed movement of a lymphocyte in response to an external stimulus.
|
SAA1,
CCL3,
CCL4,
CCL2,
ADAM8,
CCL20,
CCL8,
CKLF
|
GO:0048250
|
BP
|
mitochondrial iron ion transport
|
The directed movement of iron ions into, out of or within a mitochondrion.
|
SLC25A37
|
GO:0048251
|
BP
|
elastic fiber assembly
|
Assembly of the extracellular matrix fibers that enables the matrix to recoil after transient stretching.
|
TNXB,
LOX,
MYH11,
THSD4
|
GO:0048255
|
BP
|
mRNA stabilization
|
Prevention of degradation of mRNA molecules. In the absence of compensating changes in other processes, the slowing of mRNA degradation can result in an overall increase in the population of active mRNA molecules.
|
MEIOC,
SLC11A1,
E2F1,
CIRBP,
HNRNPD,
ELAVL1,
PAIP1,
NOCT,
THRAP3
|
GO:0048260
|
BP
|
positive regulation of receptor-mediated endocytosis
|
Any process that activates or increases the frequency, rate or extent of receptor mediated endocytosis, the uptake of external materials by cells, utilizing receptors to ensure specificity of transport.
|
HIP1,
TF,
VTN,
SERPINE1,
PPT1,
B2M,
HFE,
LDLRAP1,
APOA5,
BICD1,
RAB21
|
GO:0048261
|
BP
|
negative regulation of receptor-mediated endocytosis
|
Any process that stops, prevents, or reduces the frequency, rate or extent of receptor mediated endocytosis, the uptake of external materials by cells, utilizing receptors to ensure specificity of transport.
|
APOC1,
APOC3,
RAC1,
PICALM,
RABGEF1
|
GO:0048263
|
BP
|
determination of dorsal identity
|
Determination of the identity of part of an organism or organ where those parts are of the type that occur in the dorsal region. Identity is considered to be the aggregate of characteristics by which a structure is recognized.
|
GREM1,
NBL1,
GREM2
|
GO:0048265
|
BP
|
response to pain
|
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pain stimulus. Pain stimuli cause activation of nociceptors, peripheral receptors for pain, include receptors which are sensitive to painful mechanical stimuli, extreme heat or cold, and chemical stimuli.
|
COMT
|
GO:0048266
|
BP
|
behavioral response to pain
|
Any process that results in a change in the behavior of an organism as a result of a pain stimulus. Pain stimuli cause activation of nociceptors, peripheral receptors for pain, include receptors which are sensitive to painful mechanical stimuli, extreme heat or cold, and chemical stimuli.
|
THBS1,
TSPO,
THBS4,
GIT2,
SCN9A,
TRPV1
|
GO:0048268
|
BP
|
clathrin coat assembly
|
The process that results in the assembly of clathrin triskelia into the ordered structure known as a clathrin cage.
|
HIP1,
PIK3C2A,
EPS15,
NSG1,
AP2S1,
AP2B1,
FCHO2,
PICALM
|
GO:0048278
|
BP
|
vesicle docking
|
The initial attachment of a transport vesicle membrane to the target membrane, mediated by proteins protruding from the membrane of the vesicle and the target membrane. Docking requires only that the two membranes come close enough for these proteins to interact and adhere.
|
EXOC5,
STX7,
STX6,
STX11,
SYT1,
STX2,
CAV2,
STX4,
STX3,
BVES,
NDRG4,
CEP83
|
GO:0048280
|
BP
|
vesicle fusion with Golgi apparatus
|
The joining of the lipid bilayer membrane around a vesicle to the lipid bilayer membrane around the Golgi.
|
GOSR2,
SEC22B,
VAMP7,
SEC22A,
VTI1B
|
GO:0048284
|
BP
|
organelle fusion
|
The creation of a single organelle from two or more organelles.
|
STX4
|
GO:0048286
|
BP
|
lung alveolus development
|
The process whose specific outcome is the progression of the alveolus over time, from its formation to the mature structure. The alveolus is a sac for holding air in the lungs; formed by the terminal dilation of air passageways.
|
FOXP2,
TCF21,
HS6ST1,
ADA,
PDGFA,
BMP4,
LIF,
EDN2,
FGFR2,
IGFBP5,
FLT4,
BMPR2,
PDPN,
CIC,
HOPX,
RC3H2,
SEPN1,
ERRFI1,
MAPK8IP3
|
GO:0048291
|
BP
|
isotype switching to IgG isotypes
|
The switching of activated B cells from IgM biosynthesis to biosynthesis of an IgG isotype, accomplished through a recombination process involving an intrachromosomal deletion between switch regions that reside 5' of the IgM and one of the IgG constant region gene segments in the immunoglobulin heavy chain locus.
|
HSPD1
|
GO:0048294
|
BP
|
negative regulation of isotype switching to IgE isotypes
|
Any process that stops, prevents, or reduces the frequency, rate or extent of isotype switching to IgE isotypes.
|
BCL6,
NDFIP1,
FOXP3
|
GO:0048295
|
BP
|
positive regulation of isotype switching to IgE isotypes
|
Any process that activates or increases the frequency, rate or extent of isotype switching to IgE isotypes.
|
CLCF1
|
GO:0048298
|
BP
|
positive regulation of isotype switching to IgA isotypes
|
Any process that activates or increases the frequency, rate or extent of isotype switching to IgA isotypes.
|
TNFSF13,
WHSC1,
TGFB1
|
GO:0048302
|
BP
|
regulation of isotype switching to IgG isotypes
|
Any process that modulates the frequency, rate or extent of isotype switching to IgG isotypes.
|
NDFIP1,
FOXP3
|
GO:0048304
|
BP
|
positive regulation of isotype switching to IgG isotypes
|
Any process that activates or increases the frequency, rate or extent of isotype switching to IgG isotypes.
|
CD28
|
GO:0048305
|
BP
|
immunoglobulin secretion
|
The regulated release of immunoglobulins from a B cell or plasma cell, whose mechanism includes the use of alternate polyadenylylation signals to favor the biosynthesis of secreted forms of immunoglobulin over membrane-bound immunoglobulin.
|
TRAF3IP2,
CD40LG,
TNFSF13B
|
GO:0048311
|
BP
|
mitochondrion distribution
|
Any process that establishes the spatial arrangement of mitochondria between and within cells.
|
MEF2A,
MTM1
|
GO:0048312
|
BP
|
intracellular distribution of mitochondria
|
Any process that establishes the spatial arrangement of mitochondria within the cell.
|
SYNJ2BP
|
GO:0048318
|
BP
|
axial mesoderm development
|
The process whose specific outcome is the progression of the axial mesoderm over time, from its formation to the mature structure. The axial mesoderm includes the prechordal mesoderm and the chordamesoderm. It gives rise to the prechordal plate and to the notochord.
|
RPL38
|
GO:0048320
|
BP
|
axial mesoderm formation
|
The process that gives rise to the axial mesoderm. This process pertains to the initial formation of the structure from unspecified parts.
|
AXIN1
|
GO:0048333
|
BP
|
mesodermal cell differentiation
|
The process in which a relatively unspecialized cell acquires the specialized features of a mesoderm cell.
|
KDM6A,
ITGB3,
ITGB1,
INHBA,
ITGB4,
ITGA2,
FGFR2,
ITGA3,
HMGA2
|
GO:0048339
|
BP
|
paraxial mesoderm development
|
The process whose specific outcome is the progression of the paraxial mesoderm over time, from its formation to the mature structure. The paraxial mesoderm is the mesoderm located bilaterally adjacent to the notochord and neural tube.
|
FGFR1,
YAP1,
TCF15,
TEAD2
|
GO:0048340
|
BP
|
paraxial mesoderm morphogenesis
|
The process in which the anatomical structures of the paraxial mesoderm are generated and organized.
|
SMAD3,
SMAD2
|
GO:0048341
|
BP
|
paraxial mesoderm formation
|
The process that gives rise to the paraxial mesoderm. This process pertains to the initial formation of the structure from unspecified parts.
|
WNT5A,
FOXC1,
EXOC4
|
GO:0048352
|
BP
|
paraxial mesoderm structural organization
|
The process that contributes to the act of creating the structural organization of the paraxial mesoderm. This process pertains to the physical shaping of a rudimentary structure.
|
BMPR1A
|
GO:0048368
|
BP
|
lateral mesoderm development
|
The process whose specific outcome is the progression of the lateral mesoderm over time, from its formation to the mature structure.
|
BMPR1A,
YAP1,
TEAD2
|
GO:0048378
|
BP
|
regulation of lateral mesodermal cell fate specification
|
Any process that modulates the frequency, rate or extent of lateral mesoderm cell fate specification.
|
FGFR1,
BMPR1A
|
GO:0048382
|
BP
|
mesendoderm development
|
The process whose specific outcome is the progression of the mesendoderm over time, from its formation to the mature structure. In animal embryos, mesendoderm development gives rise to both mesoderm and endoderm tissues.
|
BMPR1A,
ZFP36L1
|
GO:0048384
|
BP
|
retinoic acid receptor signaling pathway
|
The series of molecular signals generated as a consequence of a retinoic acid receptor binding to one of its physiological ligands.
|
TBX1,
ACTN4,
ALDH1A2,
RXRB,
NR1H2,
CREM,
KMT2E,
CYP26B1
|
GO:0048385
|
BP
|
regulation of retinoic acid receptor signaling pathway
|
Any process that modulates the frequency, rate or extent of retinoic acid receptor signaling pathway activity.
|
AKR1C3
|
GO:0048386
|
BP
|
positive regulation of retinoic acid receptor signaling pathway
|
Any process that activates or increases the frequency, rate or extent of retinoic acid receptor signaling pathway activity.
|
CTBP2
|
GO:0048387
|
BP
|
negative regulation of retinoic acid receptor signaling pathway
|
Any process that stops, prevents, or reduces the frequency, rate or extent of retinoic acid receptor signaling pathway activity.
|
CNOT1,
CYP26A1,
DHRS3,
CALR,
EZH2,
CYP26B1
|
GO:0048388
|
BP
|
endosomal lumen acidification
|
Any process that reduces the pH of the endosomal lumen, measured by the concentration of the hydrogen ion.
|
CLCN3
|
GO:0048389
|
BP
|
intermediate mesoderm development
|
The process whose specific outcome is the progression of the intermediate mesoderm over time, from its formation to the mature structure. The intermediate mesoderm is located between the lateral mesoderm and the paraxial mesoderm. It develops into the kidney and gonads.
|
OSR1
|
GO:0048392
|
BP
|
intermediate mesodermal cell differentiation
|
The process in which a relatively unspecialized cell acquires specialized features of an intermediate mesoderm cell.
|
BMP4
|
GO:0048468
|
BP
|
cell development
|
The process whose specific outcome is the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.
|
MSTN,
IRF6,
GDF9,
MAF,
GDF11,
BMP15,
INHA,
INHBA,
INHBB,
BMP3,
BMP1,
BMP8B,
GJC1,
GDF5,
GATA4,
INHBC,
ARID5B,
BMP8A,
GATA6,
GDF15,
TRPS1
|
GO:0048469
|
BP
|
cell maturation
|
A developmental process, independent of morphogenetic (shape) change, that is required for a cell to attain its fully functional state.
|
TUSC2,
GDF11,
FGFR1,
VEGFA,
CTNNB1,
PPARG,
ASCL1,
SOX8,
PLP1,
ID2,
RUNX2,
CBFB,
HES1,
EPAS1
|
GO:0048477
|
BP
|
oogenesis
|
The complete process of formation and maturation of an ovum or female gamete from a primordial female germ cell. Examples of this process are found in Mus musculus and Drosophila melanogaster.
|
DIAPH2,
ERCC1,
MLH1,
H3F3A,
TRIP13,
ASPM,
PAQR8,
PAQR5,
FMN2,
DDX20,
KIAA0430
|
GO:0048478
|
BP
|
replication fork protection
|
Any process that prevents the collapse of stalled replication forks.
|
BRCA2,
BLM,
FBXO18,
TIPIN
|
GO:0048484
|
BP
|
enteric nervous system development
|
The process whose specific outcome is the progression of the enteric nervous system over time, from its formation to the mature structure. The enteric nervous system is composed of two ganglionated neural plexuses in the gut wall which form one of the three major divisions of the autonomic nervous system. The enteric nervous system innervates the gastrointestinal tract, the pancreas, and the gall bladder. It contains sensory neurons, interneurons, and motor neurons. Thus the circuitry can autonomously sense the tension and the chemical environment in the gut and regulate blood vessel tone, motility, secretions, and fluid transport. The system is itself governed by the central nervous system and receives both parasympathetic and sympathetic innervation.
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EDNRA,
SOX8,
PHACTR4
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GO:0048485
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BP
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sympathetic nervous system development
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The process whose specific outcome is the progression of the sympathetic nervous system over time, from its formation to the mature structure. The sympathetic nervous system is one of the two divisions of the vertebrate autonomic nervous system (the other being the parasympathetic nervous system). The sympathetic preganglionic neurons have their cell bodies in the thoracic and lumbar regions of the spinal cord and connect to the paravertebral chain of sympathetic ganglia. Innervate heart and blood vessels, sweat glands, viscera and the adrenal medulla. Most sympathetic neurons, but not all, use noradrenaline as a post-ganglionic neurotransmitter.
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NTRK1,
ASCL1,
SOX4,
SEMA3A
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GO:0048488
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BP
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synaptic vesicle endocytosis
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Clathrin-mediated endocytosis of presynaptic membrane that recycles synaptic vesicle membrane and its components following synaptic vesicle exocytosis. This process starts with coating of the membrane with adaptor proteins and clathrin prior to invagination and ends when uncoating has finished.
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SYNJ1,
PIP5K1C,
SYT1,
CANX,
SNCA,
CDK5,
ITSN1,
DENND1A,
SH3GL2,
PACSIN1
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GO:0048489
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BP
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synaptic vesicle transport
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The directed movement of synaptic vesicles.
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TOR1A,
SYNJ1,
SNAPIN,
CTNNB1,
RAB27A,
DPYSL2
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GO:0048490
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BP
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anterograde synaptic vesicle transport
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The directed movement of synaptic vesicle along axonal microtubules from the cell body to the presynapse.
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AP3D1,
SNAPIN,
AP3M2,
AP3S2,
BLOC1S1,
BLOC1S3,
BLOC1S6,
AP3M1
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GO:0048496
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BP
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maintenance of animal organ identity
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The process in which the identity of an animal organ is maintained. Identity is considered to be the aggregate of characteristics by which a structure is recognized.
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NPHP3,
GPR98,
PKP2
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GO:0048499
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BP
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synaptic vesicle membrane organization
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A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the membrane surrounding a synaptic vesicle.
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AP3D1
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GO:0048505
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BP
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regulation of timing of cell differentiation
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The process controlling the activation and/or rate at which relatively unspecialized cells acquire specialized features. Any process that modulates the rate, frequency or extent of the XXX at a consistent predetermined time point during its development.
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SERPINE2,
FGF9
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GO:0048511
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BP
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rhythmic process
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Any process pertinent to the generation and maintenance of rhythms in the physiology of an organism.
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ROCK2,
TOP2A,
DDX5,
SFPQ,
PPARG,
NKX2-1,
MAPK8,
MAPK9,
PRKAA2,
SIK1,
RACK1,
PRKDC,
CDK5,
CBX3,
NR1D2,
TWIST1,
EZH2,
HLF,
CCAR2,
NLGN1,
ENOX1,
PSPC1,
CREBBP,
KAT2B,
SUV39H2,
KDM5B,
BTRC
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GO:0048512
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BP
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circadian behavior
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The specific behavior of an organism that recurs with a regularity of approximately 24 hours.
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USP2,
TP53,
CSNK1E,
BTBD9
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GO:0048513
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BP
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animal organ development
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Development of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.
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HTT
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GO:0048514
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BP
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blood vessel morphogenesis
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The process in which the anatomical structures of blood vessels are generated and organized. The blood vessel is the vasculature carrying blood.
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TBX1,
GJA1,
CDH2,
RASA1,
NR2F2,
FLT4,
ID1,
SYK,
SOS1,
CYP1B1
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GO:0048515
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BP
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spermatid differentiation
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The process whose specific outcome is the progression of a spermatid over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.
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NPHP1,
BAX,
MAST2,
RHBDD1
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GO:0048524
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BP
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positive regulation of viral process
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Any process that activates or increases the frequency, rate or extent of a multi-organism process in which a virus is a participant.
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VPS4B,
RAB7A,
MVB12A
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GO:0048525
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BP
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negative regulation of viral process
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Any process that stops, prevents, or reduces the frequency, rate or extent of a multi-organism process in which a virus is a participant.
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APCS,
MBL2,
APOBEC3G
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GO:0048532
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BP
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anatomical structure arrangement
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The process that gives rise to the configuration of the constituent parts of an anatomical structure. This process pertains to the physical shaping of a rudimentary structure. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.
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RAC1
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