GO ID |
Ontology |
GO Term |
Term Definition |
Proteins |
GO:0051563
|
BP
|
smooth endoplasmic reticulum calcium ion homeostasis
|
Any process involved in the maintenance of an internal steady state of calcium ions within the smooth endoplasmic reticulum of a cell or between the smooth endoplasmic reticulum and its surroundings.
|
APP,
PSEN1
|
GO:0051567
|
BP
|
histone H3-K9 methylation
|
The modification of histone H3 by addition of one or more methyl groups to lysine at position 9 of the histone.
|
EHMT2,
SETDB2
|
GO:0051568
|
BP
|
histone H3-K4 methylation
|
The modification of histone H3 by addition of one or more methyl groups to lysine at position 4 of the histone.
|
KDM6A,
RBBP5,
KMT2E,
KMT2C,
ASH1L,
ASH2L,
KMT2B
|
GO:0051569
|
BP
|
regulation of histone H3-K4 methylation
|
Any process that modulates the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 4 of histone H3.
|
CTCFL,
PYGO2,
ZNF335,
KMT2B
|
GO:0051570
|
BP
|
regulation of histone H3-K9 methylation
|
Any process that modulates the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 9 of histone H3.
|
SETD7
|
GO:0051571
|
BP
|
positive regulation of histone H3-K4 methylation
|
Any process that activates or increases the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 4 of histone H3.
|
OGT,
GCG,
DNMT1,
CTNNB1,
BRCA1,
SMAD4,
RTF1,
DNMT3B
|
GO:0051572
|
BP
|
negative regulation of histone H3-K4 methylation
|
Any process that stops, prevents, or reduces the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 4 of histone H3.
|
KDM1A,
H2AFY,
BRCA1
|
GO:0051573
|
BP
|
negative regulation of histone H3-K9 methylation
|
Any process that stops, prevents, or reduces the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 9 of histone H3.
|
KDM1A,
DNMT1,
BRCA1,
DNMT3B
|
GO:0051574
|
BP
|
positive regulation of histone H3-K9 methylation
|
Any process that activates or increases the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 9 of histone H3.
|
BRCA1
|
GO:0051582
|
BP
|
positive regulation of neurotransmitter uptake
|
Any process that activates or increases the frequency, rate or extent of the directed movement of a neurotransmitter into a neuron or glial cell.
|
PARK2
|
GO:0051583
|
BP
|
dopamine uptake involved in synaptic transmission
|
The directed movement of dopamine into a presynaptic neuron or glial cell. In this context, dopamine is a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline.
|
PARK2,
SNCA
|
GO:0051584
|
BP
|
regulation of dopamine uptake involved in synaptic transmission
|
Any process that modulates the frequency, rate or extent of the directed movement of the catecholamine neurotransmitter dopamine into a cell.
|
TOR1A,
DRD2
|
GO:0051585
|
BP
|
negative regulation of dopamine uptake involved in synaptic transmission
|
Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of dopamine into a presynaptic neuron or glial cell.
|
SNCA
|
GO:0051586
|
BP
|
positive regulation of dopamine uptake involved in synaptic transmission
|
Any process that activates or increases the frequency, rate or extent of the directed movement of dopamine into a cell.
|
DRD2,
RAB3B
|
GO:0051591
|
BP
|
response to cAMP
|
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate) stimulus.
|
PER1,
NDUFS4,
PAX4,
LDHA,
FOS,
COL1A1,
JUN,
SPARC,
TYR,
FOSL1,
AREG,
NME1,
PFKFB1,
JUNB,
JUND,
SDC1,
AGXT,
DUSP1,
BSG,
SREBF1,
PLA2G5,
FOSB,
TEK,
CREM,
RELA,
PDE3A,
CDO1,
CARM1,
PPARGC1B,
MMP19,
CITED1,
DUOX2,
DUOX1
|
GO:0051592
|
BP
|
response to calcium ion
|
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus.
|
PTGES,
AHCYL1,
PDCD6,
ENTPD6,
SLC25A12,
SEC31A,
EGFR,
PENK,
FGA,
FGB,
FGG,
IL6,
THBS1,
SPARC,
SDC1,
CAPN3,
DUSP1,
SLC6A1,
GDI1,
TRPC1,
ANXA11,
CALM2,
CAV1,
PPP3CA,
KCNMA1,
ADAM9,
TRPC3,
HNRNPD,
ITPR3,
HOMER1,
TPH2,
TTN,
AQP3,
BAD,
S100A16,
TRPV6,
TXNIP,
SLC25A13
|
GO:0051593
|
BP
|
response to folic acid
|
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a folic acid stimulus.
|
TYMS,
EEF2,
MTHFR,
ASCL1
|
GO:0051597
|
BP
|
response to methylmercury
|
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylmercury stimulus.
|
S100B,
ALAD,
ARSB,
CPOX,
ANK2
|
GO:0051598
|
BP
|
meiotic recombination checkpoint
|
A checkpoint that acts during late prophase I (pachytene) and prevents segregation of homologous chromosomes until recombination is completed, ensuring proper distribution of the genetic material to the gametes.
|
RAD1
|
GO:0051599
|
BP
|
response to hydrostatic pressure
|
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrostatic pressure stimulus. Hydrostatic pressure is the force acting on an object in a system where the fluid is at rest (as opposed to moving). The weight of the fluid above the object creates pressure on it.
|
NTRK1,
KRT8,
ATP2B4,
COL18A1
|
GO:0051601
|
BP
|
exocyst localization
|
Any process in which an exocyst is transported to, or maintained in, a specific location. An exocyst is a protein complex peripherally associated with the plasma membrane that determines where vesicles dock and fuse.
|
EXOC3,
TNFAIP2,
STXBP6,
EXOC1
|
GO:0051602
|
BP
|
response to electrical stimulus
|
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electrical stimulus.
|
MSTN,
NTRK1,
IL6,
TH,
CD14,
BTG2,
EEF1A2,
HNRNPD,
S100A13
|
GO:0051603
|
BP
|
proteolysis involved in cellular protein catabolic process
|
The hydrolysis of a peptide bond or bonds within a protein as part of the chemical reactions and pathways resulting in the breakdown of a protein by individual cells.
|
CLPX,
CTSL,
CTSB,
CTSH,
IDE,
CTSS,
CTSK,
CTSC,
ADAMTS12,
DNAJC3,
CASP8,
CLPP,
SCPEP1,
CTSZ,
CTSF,
ADAMTS7
|
GO:0051604
|
BP
|
protein maturation
|
Any process leading to the attainment of the full functional capacity of a protein.
|
SNAPIN,
HSPD1,
SERPINH1,
TSPAN5,
TSPAN14,
SORL1,
LMF1,
STUB1
|
GO:0051606
|
BP
|
detection of stimulus
|
The series of events in which a stimulus is received by a cell or organism and converted into a molecular signal.
|
CADM1
|
GO:0051607
|
BP
|
defense response to virus
|
Reactions triggered in response to the presence of a virus that act to protect the cell or organism.
|
PLSCR1,
POLR3G,
TLR3,
BNIP3L,
CRCP,
IL33,
IFNA1 ,
IFNA16,
ISG15,
IL6,
PTPRC,
BCL2,
IRF1,
IFITM1,
IFNAR1,
GBP1,
IFNAR2,
STAT2,
F2RL1,
ADARB1,
IRF9,
IFITM3,
RELA,
RNASEL,
IL10RB,
BST2,
HYAL2,
ILF3,
BNIP3,
FADD,
DNAJC3,
IFIT5,
SERINC3,
PMAIP1,
TRIM25,
IFI16,
MICA,
NCBP3,
IFI44L,
MAVS,
SERINC5,
NLRC5,
IFNE,
TRIM22,
LILRB1,
ISG20,
ITCH,
LYST,
SPON2,
POLR3C,
TRIM34,
GBP3,
POLR3F,
APOBEC3G,
GPAM,
EXOSC4,
POLR3B,
DDIT4,
EIF2AK4,
DMBT1,
APOBEC3B,
TBK1,
PYCARD,
POLR3K,
SAMHD1,
ZNF175
|
GO:0051612
|
BP
|
negative regulation of serotonin uptake
|
Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of serotonin into a cell.
|
SNCA,
GPM6B
|
GO:0051615
|
BP
|
histamine uptake
|
The directed movement of histamine into a cell, typically presynaptic neurons or glial cells. Histamine is a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans.
|
SLC22A3
|
GO:0051622
|
BP
|
negative regulation of norepinephrine uptake
|
Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of norepinephrine into a cell.
|
SNCA
|
GO:0051638
|
BP
|
barbed-end actin filament uncapping
|
The removal of capping protein from the barbed (or plus) end of actin filaments to free the ends for addition, exchange or removal of further actin subunits.
|
LRRC16A
|
GO:0051639
|
BP
|
actin filament network formation
|
The assembly of a network of actin filaments; actin filaments on different axes and with differing orientations are crosslinked together to form a mesh of filaments.
|
COBL,
ACTN1,
LCP1,
PLS1,
COBLL1,
LRRC16A
|
GO:0051640
|
BP
|
organelle localization
|
Any process in which an organelle is transported to, and/or maintained in, a specific location.
|
STX7
|
GO:0051641
|
BP
|
cellular localization
|
A localization process that takes place at the cellular level; as a result of a cellular localization process, a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within or in the membrane of a cell.
|
MYO1D
|
GO:0051642
|
BP
|
centrosome localization
|
Any process in which a centrosome is transported to, and/or maintained in, a specific location within the cell.
|
AURKA,
DYNC1LI2,
PLXNA2,
NIN,
SYNE2,
NDEL1,
NDE1,
SUN2
|
GO:0051643
|
BP
|
endoplasmic reticulum localization
|
Any process in which endoplasmic reticulum is transported to, and/or maintained in, a specific location within the cell.
|
MYO5A
|
GO:0051645
|
BP
|
Golgi localization
|
Any process in which the Golgi is transported to, and/or maintained in, a specific location within the cell.
|
DAB1,
STK11,
HOOK3
|
GO:0051646
|
BP
|
mitochondrion localization
|
Any process in which a mitochondrion or mitochondria are transported to, and/or maintained in, a specific location within the cell.
|
MFN2,
PLIN5,
BRAT1,
HDAC6
|
GO:0051647
|
BP
|
nucleus localization
|
Any process in which the nucleus is transported to, and/or maintained in, a specific location within the cell.
|
BIN1
|
GO:0051649
|
BP
|
establishment of localization in cell
|
Any process, occuring in a cell, that localizes a substance or cellular component. This may occur via movement, tethering or selective degradation.
|
ZWINT
|
GO:0051650
|
BP
|
establishment of vesicle localization
|
The directed movement of a vesicle to a specific location.
|
RAB11A
|
GO:0051651
|
BP
|
maintenance of location in cell
|
Any process in which a substance or cellular entity, such as a protein complex or organelle, is maintained in a specific location within, or in the membrane of, a cell, and is prevented from moving elsewhere.
|
APOE
|
GO:0051653
|
BP
|
spindle localization
|
Any process in which is the spindle is transported to, and/or maintained in, a specific location.
|
WASL,
ACTR3,
ACTR2,
ASPM
|
GO:0051654
|
BP
|
establishment of mitochondrion localization
|
The directed movement of the mitochondrion to a specific location.
|
FEZ1
|
GO:0051656
|
BP
|
establishment of organelle localization
|
The directed movement of an organelle to a specific location.
|
CROCC
|
GO:0051659
|
BP
|
maintenance of mitochondrion location
|
Any process in which a mitochondrion is maintained in a specific location within a cell and prevented from moving elsewhere.
|
ALB
|
GO:0051660
|
BP
|
establishment of centrosome localization
|
The directed movement of the centrosome to a specific location.
|
EZR,
DLG1
|
GO:0051661
|
BP
|
maintenance of centrosome location
|
Any process in which a centrosome is maintained in a specific location within a cell and prevented from moving elsewhere.
|
GPSM2,
ASPM,
TBCCD1
|
GO:0051665
|
BP
|
membrane raft localization
|
Any process in which membrane rafts are transported to, or maintained in, a specific location. Membrane rafts are small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes.
|
RALA
|
GO:0051668
|
BP
|
localization within membrane
|
Any process in which a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within a membrane.
|
CDH13,
RAC1
|
GO:0051683
|
BP
|
establishment of Golgi localization
|
The directed movement of the Golgi to a specific location.
|
CDC42,
YWHAZ,
ARHGAP21,
PDCD10,
COPG1
|
GO:0051684
|
BP
|
maintenance of Golgi location
|
Any process in which the Golgi is maintained in a specific location within a cell and prevented from moving elsewhere.
|
ARHGAP21,
TBCCD1
|
GO:0051693
|
BP
|
actin filament capping
|
The binding of a protein or protein complex to the end of an actin filament, thus preventing the addition, exchange or removal of further actin subunits.
|
SPTBN1,
SPTBN4
|
GO:0051694
|
BP
|
pointed-end actin filament capping
|
The binding of a protein or protein complex to the pointed (or minus) end of an actin filament, thus preventing the addition, exchange or removal of further actin subunits.
|
TMOD1,
LMOD1
|
GO:0051695
|
BP
|
actin filament uncapping
|
The removal of capping protein from the end of actin filaments to free the ends for addition, exchange or removal of further actin subunits.
|
ACTN2
|
GO:0051702
|
BP
|
interaction with symbiont
|
An interaction between two organisms living together in more or less intimate association. The term symbiont is used for the smaller (macro) of the two members of a symbiosis; the various forms of symbiosis include parasitism, commensalism and mutualism.
|
GPX1
|
GO:0051707
|
BP
|
response to other organism
|
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from another living organism.
|
KRT8
|
GO:0051716
|
BP
|
cellular response to stimulus
|
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus by a cell and ends with a change in state or activity or the cell.
|
EIF2B1,
EIF2B3,
EIF2B4
|
GO:0051725
|
BP
|
protein de-ADP-ribosylation
|
The process of removing one or more ADP-ribose residues from a protein.
|
MACROD2,
ADPRH,
MACROD1
|
GO:0051726
|
BP
|
regulation of cell cycle
|
Any process that modulates the rate or extent of progression through the cell cycle.
|
CLIC1,
ARNTL,
GADD45B,
RAD51D,
CCNB2,
GADD45G,
INHA,
JUN,
ITGB1,
PTPRC,
MYBL2,
IRF1,
BCR,
CCNB1,
JUNB,
JUND,
SON,
MAK,
CDK11B,
RBL1,
WEE1,
CDC25A,
CDC25C,
GRK5,
STAT3,
LEP,
CDK8,
CENPF,
TSC2,
PLK1,
RACK1,
ADARB1,
CDK3,
CDK16,
ID3,
FOXM1,
RBBP4,
EP300,
TARDBP,
SRSF5,
SKP2,
CCNI,
BOP1,
E2F2,
PUM1,
KIAA0101,
CCNG2,
LIN52,
SIRT2,
PHACTR4,
BAP1,
MASTL,
LIN37,
PRR11,
UHRF2,
MNT,
PKMYT1,
CDK19,
BEX2,
HIPK2,
TXLNG,
CDK12,
DTL,
CDK11A,
L3MBTL1
|
GO:0051754
|
BP
|
meiotic sister chromatid cohesion, centromeric
|
The cell cycle process in which centromeres of sister chromatids are joined during meiosis.
|
RAD21,
PPP2R1A,
SGOL2
|
GO:0051758
|
BP
|
homologous chromosome movement towards spindle pole involved in homologous chromosome segregation
|
The directed movement of homologous chromosomes from the center of the spindle towards the spindle poles, mediated by the shortening of microtubules attached to the chromosomes, that contributes to meiosis I.
|
FMN2
|
GO:0051764
|
BP
|
actin crosslink formation
|
The process in which two or more actin filaments are connected together by proteins that act as crosslinks between the filaments. The crosslinked filaments may be on the same or differing axes.
|
ACTN1,
LCP1,
FLNA,
EPS8,
DPYSL3,
PLS1,
BAIAP2L1
|
GO:0051770
|
BP
|
positive regulation of nitric-oxide synthase biosynthetic process
|
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of a nitric oxide synthase enzyme.
|
TLR4,
TLR2,
JAK2,
CCL2,
NAMPT,
MAP2K6,
CCL20
|
GO:0051771
|
BP
|
negative regulation of nitric-oxide synthase biosynthetic process
|
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of a nitric-oxide synthase enzyme.
|
EDN1,
GSTP1,
PGGT1B,
VIMP
|
GO:0051775
|
BP
|
response to redox state
|
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating redox state. Redox state refers to the balance of oxidized versus reduced forms of electron donors and acceptors in an organelle, cell or organ; plastoquinone, glutathione (GSH/GSSG), and nicotinamide nucleotides (NAD+/NADH and NADP+/NADPH) are among the most important.
|
ARNTL,
SIRT2,
RYR2,
NPAS2,
VIMP,
GLRX2
|
GO:0051781
|
BP
|
positive regulation of cell division
|
Any process that activates or increases the frequency, rate or extent of cell division.
|
ITGB1BP1,
EREG,
PDGFB,
TGFA,
TGFB1,
IGF2,
IL1A,
IL1B,
PPBP,
PDGFA,
FGF2,
VEGFA,
TAL1,
MDK,
FGF7,
FGFR2,
FGF9,
BTC,
THBS4,
HTR2B,
PGF,
VEGFB,
VEGFC,
TGFB2,
YBX1,
CSPP1,
SIRT2,
PDGFD,
GAREM1,
PDGFC
|
GO:0051782
|
BP
|
negative regulation of cell division
|
Any process that stops, prevents, or reduces the frequency, rate or extent of cell division.
|
MYC,
BLM,
PTCH1,
TXNIP,
INTU
|
GO:0051788
|
BP
|
response to misfolded protein
|
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a misfolded protein stimulus.
|
CLU,
HDAC6
|
GO:0051791
|
BP
|
medium-chain fatty acid metabolic process
|
The chemical reactions and pathways involving medium-chain fatty acids, any fatty acid with a chain length of between C6 and C12.
|
CROT
|
GO:0051792
|
BP
|
medium-chain fatty acid biosynthetic process
|
The chemical reactions and pathways resulting in the formation of any fatty acid with a chain length of between C6 and C12.
|
ACOT7
|
GO:0051795
|
BP
|
positive regulation of catagen
|
Any process that activates or increases the frequency, rate or extent of catagen, the regression phase of the hair cycle.
|
GAL,
TGFB2
|
GO:0051797
|
BP
|
regulation of hair follicle development
|
Any process that modulates the frequency, rate or extent of hair follicle development.
|
SMAD4,
HPSE
|
GO:0051798
|
BP
|
positive regulation of hair follicle development
|
Any process that activates or increases the frequency, rate or extent of hair follicle development.
|
TNF,
FST,
KRT17,
TRADD,
HPSE
|
GO:0051823
|
BP
|
regulation of synapse structural plasticity
|
Any process that modulates the frequency, rate or extent of synapse structural plasticity. Synapse structural plasticity is a type of cytoskeletal remodeling; this remodeling is induced by stimuli that can lead to long term potentiation and it can be activity-dependent or -independent. Examples of cytoskeletal changes include the formation of new spines and increase in spine size; this can be accompanied by the insertion of greater numbers of glutamate (or other neurotransmitter) receptors into the post-synaptic membrane.
|
DRD2,
CTNNA2,
DMPK
|
GO:0051835
|
BP
|
positive regulation of synapse structural plasticity
|
Any process that activates, maintains or increases the frequency, rate or extent of synaptic structural plasticity.
|
CDC42,
CAMK1,
FRMPD4
|
GO:0051865
|
BP
|
protein autoubiquitination
|
The ubiquitination by a protein of one or more of its own amino acid residues, or residues on an identical protein. Ubiquitination occurs on the lysine residue by formation of an isopeptide crosslink.
|
WWP2,
PARK2,
TRIM13,
RNF8,
TRIM37,
UBE4B,
CNOT4,
RAG1,
BRCA1,
UBE2A,
UBE2D3,
UBE2B,
RNF141,
UHRF2,
UHRF1,
UBE2T,
RAD18,
RNF146,
RNF181,
AMFR,
STUB1
|
GO:0051866
|
BP
|
general adaptation syndrome
|
General adaptation syndrome is the set of changes in various organ systems of the body, especially the pituitary-endocrine system, in response to a wide range of strong external stimuli, both physiological and psychological. It is described as having three stages: alarm reaction, where the body detects the external stimulus; adaptation, where the body engages defensive countermeasures against the stressor; and exhaustion, where the body begins to run out of defenses.
|
NR4A2
|
GO:0051867
|
BP
|
general adaptation syndrome, behavioral process
|
The set of behavioral processes that occur as part of the general adaptation syndrome, the response of the body to a strong, stressful stimulus.
|
PENK
|
GO:0051873
|
BP
|
killing by host of symbiont cells
|
Any process mediated by an organism that results in the death of cells in the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.
|
MBL2
|
GO:0051877
|
BP
|
pigment granule aggregation in cell center
|
The directed movement of dispersed pigment granules towards the center of the cell.
|
BBS7,
MKKS
|
GO:0051881
|
BP
|
regulation of mitochondrial membrane potential
|
Any process that modulates the establishment or extent of the mitochondrial membrane potential, the electric potential existing across the mitochondrial membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane.
|
CLIC1,
PARK2,
TUSC2,
BCL2,
NDUFS1,
UCP2,
BAX,
PID1,
SPG20,
SLC25A36,
PINK1,
PANK2,
PRELID1
|
GO:0051882
|
BP
|
mitochondrial depolarization
|
The process in which the potential difference across the mitochondrial membrane is reduced from its steady state level.
|
CASP1
|
GO:0051891
|
BP
|
positive regulation of cardioblast differentiation
|
Any process that activates or increases the frequency, rate or extent of cardioblast differentiation, the process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.
|
GATA4,
TGFB2,
GATA6
|
GO:0051893
|
BP
|
regulation of focal adhesion assembly
|
Any process that modulates the frequency, rate or extent of focal adhesion formation, the establishment and maturation of focal adhesions.
|
RHOD,
DAPK3,
GREM1,
ROCK2,
EPHA3,
EFNA5,
PTK2,
GPM6B,
CORO1C,
MACF1
|
GO:0051894
|
BP
|
positive regulation of focal adhesion assembly
|
Any process that activates or increases the frequency, rate or extent of focal adhesion assembly, the establishment and maturation of focal adhesions.
|
ITGB1BP1,
VEGFA,
SDC4,
IQGAP1,
LIMS1,
PPM1F,
S100A10,
RAC1,
SMAD3,
TEK,
COL16A1,
PTPRJ,
SFRP1
|
GO:0051895
|
BP
|
negative regulation of focal adhesion assembly
|
Any process that stops, prevents, or reduces the frequency, rate or extent of focal adhesion assembly, the establishment and maturation of focal adhesions.
|
ITGB1BP1,
ARHGAP6,
APOD,
THBS1,
MMP14,
PTEN,
PHLDB2,
DLC1,
CORO1C
|
GO:0051896
|
BP
|
regulation of protein kinase B signaling
|
Any process that modulates the frequency, rate or extent of protein kinase B signaling, a series of reactions mediated by the intracellular serine/threonine kinase protein kinase B.
|
RRAS,
SESN3,
STK11,
NTRK2,
RICTOR
|
GO:0051897
|
BP
|
positive regulation of protein kinase B signaling
|
Any process that activates or increases the frequency, rate or extent of protein kinase B signaling, a series of reactions mediated by the intracellular serine/threonine kinase protein kinase B.
|
HAX1,
ITGB1BP1,
TNFSF11,
SPRY2,
EGFR,
TGFB1,
INS,
IGF2,
TNF,
PDGFA,
IL6,
INSR,
GPX1,
THBS1,
CCL3,
TXN,
CD28,
HCLS1,
ZP3,
IGFBP5,
CHI3L1,
TGFBR1,
LEP,
AKR1C3,
PIK3CG,
AKR1C2,
ADAM8,
NRG1,
TEK,
PTK2,
C1QBP,
PTPRJ,
ILK,
SEMA5A,
IL18,
GAS6,
ANGPT1,
ITSN1,
FAM110C,
RICTOR,
MTDH,
TSPYL5,
GCNT2,
MYDGF,
RASD2,
HBEGF,
MEIS3,
C1QTNF1,
PINK1,
OSBPL8,
NOX4,
TCF7L2,
HPSE
|
GO:0051898
|
BP
|
negative regulation of protein kinase B signaling
|
Any process that stops, prevents, or reduces the frequency, rate or extent of protein kinase B signaling, a series of reactions mediated by the intracellular serine/threonine kinase protein kinase B.
|
MSTN,
KLF4,
PDCD6,
DRD2,
DDIT3,
XDH,
TSC2,
PTEN,
RACK1,
HYAL2,
PTPRJ,
DLG1,
MTM1,
RAPGEF1,
DAG1,
SFRP5,
MAGI2,
FLCN,
PRKCDBP,
GPER1,
CIB1,
INPP5K,
LMBRD1
|
GO:0051899
|
BP
|
membrane depolarization
|
The process in which membrane potential decreases with respect to its steady-state potential, usually from negative potential to a more positive potential. For example, the initial depolarization during the rising phase of an action potential is in the direction from the negative steady-state resting potential towards the positive membrane potential that will be the peak of the action potential.
|
EDN1,
JUN,
CACNB3,
CAV1,
ADIPOQ,
CACNA1E,
P2RX4
|
GO:0051900
|
BP
|
regulation of mitochondrial depolarization
|
Any process that modulates the frequency, rate or extent of the change in the membrane potential of the mitochondria from negative to positive.
|
GCLC,
GCLM
|
GO:0051901
|
BP
|
positive regulation of mitochondrial depolarization
|
Any process that activates, maintains or increases the frequency, rate or extent of the change in the membrane potential of the mitochondria from negative to positive.
|
CCK,
DCN,
PARP1,
TSPO,
RACK1,
MLLT11
|
GO:0051902
|
BP
|
negative regulation of mitochondrial depolarization
|
Any process that stops, prevents, or reduces the frequency, rate or extent of the change in the membrane potential of the mitochondria from negative to positive.
|
BCL2
|
GO:0051917
|
BP
|
regulation of fibrinolysis
|
Any process that modulates the frequency, rate or extent of fibrinolysis, an ongoing process that solubilizes fibrin, resulting in the removal of small blood clots.
|
APOH
|
GO:0051918
|
BP
|
negative regulation of fibrinolysis
|
Any process that stops, prevents, or reduces the frequency, rate or extent of fibrinolysis, an ongoing process that solubilizes fibrin, resulting in the removal of small blood clots.
|
F2,
PLG,
APOH,
SERPINE1,
THBS1,
CPB2
|
GO:0051919
|
BP
|
positive regulation of fibrinolysis
|
Any process that activates, maintains or increases the frequency, rate or extent of fibrinolysis, an ongoing process that solubilizes fibrin, resulting in the removal of small blood clots.
|
PLG
|
GO:0051923
|
BP
|
sulfation
|
The addition of a sulfate group to a molecule.
|
SULT1A3,
SULT2A1,
CHSY1
|
GO:0051924
|
BP
|
regulation of calcium ion transport
|
Any process that modulates the frequency, rate or extent of the directed movement of calcium ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
BEST1,
AGT,
GNAI2,
BCL2,
GJA1,
PLN,
SRI,
CACNA2D1,
ANK2
|
GO:0051926
|
BP
|
negative regulation of calcium ion transport
|
Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of calcium ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
ICAM1,
PLN,
NOS3,
PTGS2,
STC1,
LILRB1,
INPP5K
|
GO:0051928
|
BP
|
positive regulation of calcium ion transport
|
Any process that activates or increases the frequency, rate or extent of the directed movement of calcium ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
CCL3,
CCL4,
CCL5,
F2R,
TSPO,
ANK2,
MYLK,
HOMER1,
P2RX4,
WNK3,
STIM2,
TRPC6
|