GO:0048793

BP

pronephros development

The process whose specific outcome is the progression of the pronephros over time, from its formation to the mature structure. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life.

PAX8, OSR1

GO:0048806

BP

genitalia development

The process whose specific outcome is the progression of the genitalia over time, from its formation to the mature structure.

WNT5A, PKD1, PTPN11, DNAJC19, CHD7

GO:0048807

BP

female genitalia morphogenesis

The process in which the anatomical structures of female genitalia are generated and organized.

RBP4

GO:0048808

BP

male genitalia morphogenesis

The process in which the anatomical structures of male genitalia are generated and organized.

AR

GO:0048812

BP

neuron projection morphogenesis

The process in which the anatomical structures of a neuron projection are generated and organized. A neuron projection is any process extending from a neural cell, such as axons or dendrites.

EGFR, NGF, GJA1, WEE1, NBL1, NEK3, DYNLT1, ILK, CTTN, SLC9A6, ANKRD27, ALS2, KIF20B, PACSIN1, ZNF335, ZSWIM6, DICER1, EPB41L3

GO:0048813

BP

dendrite morphogenesis

The process in which the anatomical structures of a dendrite are generated and organized. A dendrite is a freely branching protoplasmic process of a nerve cell.

DCLK1, RBFOX2, KLF7, ITGB1, FYN, MAP2, CTNNA2, SDC2, SLC11A2, RAC1, VLDLR, CDK5, MEF2A, MAPK8IP2, PICALM, SEMA3A, PREX2, ABI1, MINK1, TMEM106B, RERE, KIDINS220, BTBD3, FARP1

GO:0048814

BP

regulation of dendrite morphogenesis

Any process that modulates the frequency, rate or extent of dendrite morphogenesis.

PQBP1, RAP2A, SDC2, STK11, SARM1, NSMF, KNDC1, TNIK, LZTS1

GO:0048820

BP

hair follicle maturation

A developmental process, independent of morphogenetic (shape) change, that is required for a hair follicle to attain its fully functional state.

ERCC2

GO:0048821

BP

erythrocyte development

The process whose specific outcome is the progression of an erythrocyte over time, from its formation to the mature structure.

BPGM, SOX6, BCL6, SLC11A2, RPS6, JMJD6

GO:0048822

BP

enucleate erythrocyte development

The process aimed at the progression of an enucleate erythrocyte over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.

MAEA

GO:0048839

BP

inner ear development

The process whose specific outcome is the progression of the inner ear over time, from its formation to the mature structure.

MAF, LGR5, CXCL14, TGFB1, SPARC, PDGFRB, BMP2, MPV17, CDKN1B, MAPKAPK2, HOXA1, CEBPD, TGFB2, PTPN11, PLPPR4, LRP10, BMPER, ANP32B, CCM2, DUOX2

GO:0048841

BP

regulation of axon extension involved in axon guidance

Any process that modulates the frequency, rate or extent of axon extension involved in axon guidance.

PLXNC1, PLXNA2, PLXNA3, SEMA3A, PLXNA1, PLXND1

GO:0048842

BP

positive regulation of axon extension involved in axon guidance

Any process that activates, maintains or increases the frequency, rate or extent of axon extension involved in axon guidance.

NRP1, VEGFA, CXCL12, SEMA5A, BMPR2

GO:0048843

BP

negative regulation of axon extension involved in axon guidance

Any process that stops, prevents, or reduces the frequency, rate or extent of axon extension involved in axon guidance.

NRP1, SEMA3E, SEMA3D, WNT5A, PLXNA3, WNT3, SEMA3B, SEMA5A, SEMA3A, SEMA6D, SEMA3C, SEMA6A, SEMA4A, SEMA6B

GO:0048844

BP

artery morphogenesis

The process in which the anatomical structures of arterial blood vessels are generated and organized. Arteries are blood vessels that transport blood from the heart to the body and its organs.

NRP1, SMAD7, TBX1, APOE, APOB, VEGFA, GJA5, TGFBR1, HOXA1, FOXC1, HES1, ZMIZ1

GO:0048845

BP

venous blood vessel morphogenesis

The process in which the anatomical structures of venous blood vessels are generated and organized. Veins are blood vessels that transport blood from the body and its organs to the heart.

EFNB2, CCBE1, PROX1, CCM2, HEG1

GO:0048846

BP

axon extension involved in axon guidance

The long distance growth of a single cell process, that is involved in the migration of an axon growth cone, where the migration is directed to a specific target site by a combination of attractive and repulsive cues.

NRP1, NRP2, SLIT2, ALCAM, SEMA3A

GO:0048850

BP

hypophysis morphogenesis

The process in which the anatomical structures of the hypophysis are generated and organized. The pituitary gland is an endocrine gland that secretes hormones that regulate many other glands.

WNT5A

GO:0048853

BP

forebrain morphogenesis

The process in which the anatomical structures of the forebrain are generated and organized. The forebrain is the anterior of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes especially the cerebral hemispheres, the thalamus, and the hypothalamus and especially in higher vertebrates is the main control center for sensory and associative information processing, visceral functions, and voluntary motor functions).

PTEN, HHEX, UCHL5

GO:0048854

BP

brain morphogenesis

The process in which the anatomical structures of the brain are generated and organized. The brain is one of the two components of the central nervous system and is the center of thought and emotion. It is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.).

FOXO3, CDH2, CTNNA2, PSEN1, PTEN, BBS2, FANCD2, ZNF335, MKKS

GO:0048855

BP

adenohypophysis morphogenesis

The process in which the anatomical structures of the adenohypophysis are generated and organized. The adenohypophysis is the anterior part of the pituitary. It secretes a variety of hormones and its function is regulated by the hypothalamus.

DUOX2

GO:0048856

BP

anatomical structure development

The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.

SPARCL1

GO:0048858

BP

cell projection morphogenesis

The process in which the anatomical structures of a cell projection are generated and organized.

NES

GO:0048859

BP

formation of anatomical boundary

The process in which the limits of an anatomical structure are generated. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.

SMAD4

GO:0048861

BP

leukemia inhibitory factor signaling pathway

Any series of molecular signals initiated by the binding of leukemia inhibitory factor to a receptor on the surface of the target cell, and ending with regulation of a downstream cellular process, e.g. transcription.

LIF, IL6ST, LIFR, CTF1

GO:0048863

BP

stem cell differentiation

The process in which a relatively unspecialized cell acquires specialized features of a stem cell. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells.

PSMD11, A2M, KIT, LIF, EPCAM, HMGA2, FOXO4, RUNX2, PUM1, OSR1, SETD6, LIN28A, MTF2

GO:0048864

BP

stem cell development

The process whose specific outcome is the progression of the stem cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to its specific fate.

PTPRC, MSI2

GO:0048866

BP

stem cell fate specification

The process in which a cell becomes capable of differentiating autonomously into a stem cell in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed.

SOX17

GO:0048870

BP

cell motility

Any process involved in the controlled self-propelled movement of a cell that results in translocation of the cell from one place to another.

SRPX2, SKI, ETS1, ITGB4, TGFBR1, MMP14, RAC1, ADAM17, MAP2K1, DST, PTK2, PLD1, CTTN, FSCN1, PDPN, IER2

GO:0048871

BP

multicellular organismal homeostasis

Any process involved in the maintenance of an internal steady state at the level of the multicellular organism.

TNS2, PPP1R13L

GO:0048872

BP

homeostasis of number of cells

Any biological process involved in the maintenance of the steady-state number of cells within a population of cells.

IL7R, CDH2, SART3, WDR48, RRN3

GO:0048873

BP

homeostasis of number of cells within a tissue

Any biological process involved in the maintenance of the steady-state number of cells within a population of cells in a tissue.

SASH3, KRAS, PTH, FH, BCL2, F2R, CORO1A, LIPA, RAC3, RAC1, PTPN11, BAX, GIGYF2, ILDR2, TEX15

GO:0048875

BP

chemical homeostasis within a tissue

Any process involved in the maintenance of the internal steady state of the amount of a chemical at the level of the tissue.

HOMER1

GO:0048880

BP

sensory system development

The process whose specific outcome is the progression of a sensory system over time from its formation to the mature structure.

SEMA3A

GO:0048935

BP

peripheral nervous system neuron development

The process whose specific outcome is the progression of a neuron whose cell body is located in the peripheral nervous system, from initial commitment of the cell to a neuronal fate, to the fully functional differentiated neuron.

HOXD10, ETV1, RUNX1, RUNX3, NTRK2

GO:0048936

BP

peripheral nervous system neuron axonogenesis

Generation of a long process from a neuron whose cell body resides in the peripheral nervous system. The axon carries action potential from the cell body towards target cells.

NEFH

GO:0050427

BP

3'-phosphoadenosine 5'-phosphosulfate metabolic process

The chemical reactions and pathways involving 3'-phosphoadenosine 5'-phosphosulfate, a naturally occurring mixed anhydride. It is an intermediate in the formation of a variety of sulfo compounds in biological systems.

SULT1A3, ENPP1, SULT2A1, ABHD14B

GO:0050428

BP

3'-phosphoadenosine 5'-phosphosulfate biosynthetic process

The chemical reactions and pathways resulting in the formation of 3'-phosphoadenosine 5'-phosphosulfate, a naturally occurring mixed anhydride. It is an intermediate in the formation of a variety of sulfo compounds in biological systems.

PAPSS2, SLC26A2, SLC26A1

GO:0050434

BP

positive regulation of viral transcription

Any process that activates or increases the frequency, rate or extent of viral transcription.

SUPT5H, POLR2D, CCNT1, PFN1, GTF2F2, POLR2E, POLR2A, POLR2B, GTF2F1, POLR2I, NOTCH1, POLR2J, POLR2K, POLR2G, POLR2L, GTF2B, RSF1

GO:0050435

BP

beta-amyloid metabolic process

The chemical reactions and pathways involving beta-amyloid, a glycoprotein associated with Alzheimer's disease, and its precursor, amyloid precursor protein (APP).

MME, ACE, IDE, PSEN2

GO:0050482

BP

arachidonic acid secretion

The controlled release of arachidonic acid from a cell or a tissue.

ANXA1, NMB, ACE, DRD2, PLA2G2A, PLA2G5, PLA2G4A, PLA2G12A, PNPLA8

GO:0050650

BP

chondroitin sulfate proteoglycan biosynthetic process

The chemical reactions and pathways resulting in the formation of chondroitin sulfate proteoglycan, any glycoprotein whose glycosaminoglycan units are chondroitin sulfate. Chondroitin sulfates are a group of 10-60 kDa glycosaminoglycans, widely distributed in cartilage and other mammalian connective tissues; the repeat units consist of beta-(1,4)-linked D-glucuronyl beta-(1,3)-N-acetyl-D-galactosamine sulfate.

CSGALNACT1, PXYLP1, XYLT2

GO:0050651

BP

dermatan sulfate proteoglycan biosynthetic process

The chemical reactions and pathways resulting in the formation of dermatan sulfate proteoglycan, any glycoprotein whose glycosaminoglycan units are dermatan sulfate (chondroitin sulfate B). Dermatan sulfate is a glycosaminoglycan with repeats consisting of beta-(1,4)-linked L-iduronyl-beta-(1,3)-N-acetyl-D-galactosamine 4-sulfate units.

CSGALNACT1

GO:0050653

BP

chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process

The elongation of chondroitin sulfate proteoglycan chains by alternate addition of N-acetylhexosamine and GlcUA residues to the GAG-protein linkage region tetrasaccharide of chondroitin sulfate.

CSGALNACT1

GO:0050658

BP

RNA transport

The directed movement of RNA, ribonucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

HNRNPA2B1, CKAP5, RBFOX1

GO:0050663

BP

cytokine secretion

The regulated release of cytokines from a cell. Cytokines are any of a group of proteins that function to control the survival, growth and differentiation of tissues and cells, and which have autocrine and paracrine activity.

AGT, LYN, NOX5, S100A13

GO:0050665

BP

hydrogen peroxide biosynthetic process

The chemical reactions and pathways resulting in the formation of hydrogen peroxide (H2O2), a potentially harmful byproduct of aerobic cellular respiration which can cause damage to DNA.

CYP1A1, CYBB, MAOB, DUOX2, DUOX1

GO:0050667

BP

homocysteine metabolic process

The chemical reactions and pathways involving homocysteine, the amino acid alpha-amino-gamma-mercaptobutanoic acid. Homocysteine is an important intermediate in the metabolic reactions of its S-methyl derivative, methionine.

CBS, MTHFR, NOX4

GO:0050668

BP

positive regulation of homocysteine metabolic process

Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving homocysteine.

COMT

GO:0050671

BP

positive regulation of lymphocyte proliferation

Any process that activates or increases the rate or extent of lymphocyte proliferation.

IL12A, ZNF335

GO:0050672

BP

negative regulation of lymphocyte proliferation

Any process that stops, prevents or reduces the rate or extent of lymphocyte proliferation.

GAL

GO:0050673

BP

epithelial cell proliferation

The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population. Epithelial cells make up the epithelium, the covering of internal and external surfaces of the body, including the lining of vessels and other small cavities. It consists of cells joined by small amounts of cementing substances.

KIT, COL8A2, PSEN1, C6orf89, EHF

GO:0050678

BP

regulation of epithelial cell proliferation

Any process that modulates the frequency, rate or extent of epithelial cell proliferation.

SERPINB5, SMAD3, HES1, FRS2

GO:0050679

BP

positive regulation of epithelial cell proliferation

Any process that activates or increases the rate or extent of epithelial cell proliferation.

TBX1, EGFR, MYC, TGFA, TGFB1, ERBB2, IGF1, IL6, LAMB1, LAMC1, BMP4, CCL5, NME1, VEGFA, C5AR1, FGF7, FGFR2, BMP6, NME2, FGF9, BMPR1A, ID1, NOTCH1, SOX9, DLX5, MAP2K5, TWIST1, SFRP1, WDR48, OSR1, NR4A3, HTRA1, BAD, ESRP2

GO:0050680

BP

negative regulation of epithelial cell proliferation

Any process that stops, prevents or reduces the rate or extent of epithelial cell proliferation.

EREG, MTSS1, TGFB1, RB1, AR, BMP4, FGFR2, PBLD, WNT5A, CDKN2B, GDF5, SOX9, CDKN1C, HRSP12, PTEN, TGFB2, CDK6, TGFBR3, PPARD, MEF2C, DLG1, PTCH1, RUNX3, RGN, SFRP1, MARVELD3, IFT74, IFT122, WFDC1

GO:0050684

BP

regulation of mRNA processing

Any process that modulates the frequency, rate or extent of mRNA processing, those processes involved in the conversion of a primary mRNA transcript into a mature mRNA prior to its translation into polypeptide.

CDK11B, SUPT6H, SRPK1, SLTM, CDK11A

GO:0050687

BP

negative regulation of defense response to virus

Any process that stops, prevents or reduces the rate or extent of antiviral mechanisms, thereby facilitating viral replication.

TRIM38, PPM1B, C1QBP, HTRA1, ITCH

GO:0050689

BP

negative regulation of defense response to virus by host

Any host process that results in the inhibition of antiviral immune response mechanisms, thereby facilitating viral replication. The host is defined as the larger of the organisms involved in a symbiotic interaction.

MICB

GO:0050690

BP

regulation of defense response to virus by virus

Any viral process that modulates the frequency, rate, or extent of the antiviral response of the host cell or organism.

AP2A2, CD4, FYN, CD28, AP2S1, AP1S2, B2M, AP1S1, RAC1, AP2B1, ARF1, AP1B1, PAK2, ELMO1, DOCK2, AP2M1, ATP6V1H

GO:0050691

BP

regulation of defense response to virus by host

Any host process that modulates the frequency, rate, or extent of the antiviral response of a host cell or organism.

TNFAIP3, RNF216

GO:0050702

BP

interleukin-1 beta secretion

The regulated release of interleukin 1 beta from a cell.

TLR4, ABCA1, CD36, F2RL1

GO:0050703

BP

interleukin-1 alpha secretion

The regulated release of interleukin-1 alpha from a cell.

S100A13

GO:0050706

BP

regulation of interleukin-1 beta secretion

Any process that modulates the frequency, rate or extent of the regulated release of interleukin-1 beta from a cell.

FOXP1

GO:0050707

BP

regulation of cytokine secretion

Any process that modulates the frequency, rate or extent of the regulated release of cytokines from a cell.

TLR4, SOCS1, TLR5, TLR2, LYN, TLR1, GPAM

GO:0050708

BP

regulation of protein secretion

Any process that modulates the frequency, rate or extent of the controlled release of a protein from a cell.

INS, SAA1, PAM, ARFIP1, STXBP5, PIK3C3, RHBDF1, DNAJC1, STXBP5L

GO:0050709

BP

negative regulation of protein secretion

Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a protein from a cell.

INS, DRD2, ERP29, RHBDF1, DPH3

GO:0050710

BP

negative regulation of cytokine secretion

Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of cytokines from a cell.

IL6, SRGN, TNFSF4, PTGER4, BTN2A2, LGR4, FOXP3, RGCC

GO:0050711

BP

negative regulation of interleukin-1 secretion

Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of interleukin-1 from a cell.

GAS6

GO:0050712

BP

negative regulation of interleukin-1 alpha secretion

Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of interleukin-1 alpha from a cell.

IL1R2

GO:0050713

BP

negative regulation of interleukin-1 beta secretion

Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of interleukin-1 beta from a cell.

APOA1

GO:0050714

BP

positive regulation of protein secretion

Any process that activates or increases the frequency, rate or extent of the controlled release of a protein from a cell.

APBB1, TGFB1, IL1A, FGA, FGB, FGG, ANG, IGF1, EZR, BMP6, VEGFC, TGFB2, PPIA, ADAM8, ARF1, PPID, ADAM9, ANKRD1, EXPH5, SYTL4, ATP13A2, EXOC1, RPH3AL, STXBP5L

GO:0050715

BP

positive regulation of cytokine secretion

Any process that activates or increases the frequency, rate or extent of the regulated release of cytokines from a cell.

INS, TNF, IL1A, CD14, FGR, SAA1, MIF, IL10, PTGER4, HTR2B, SYK, AGTR2, GLMN, C1QTNF3, CADM1, RGCC

GO:0050716

BP

positive regulation of interleukin-1 secretion

Any process that activates or increases the frequency, rate or extent of the regulated release of interleukin-1 from a cell.

HMGB1, SAA1

GO:0050717

BP

positive regulation of interleukin-1 alpha secretion

Any process that activates or increases the frequency, rate or extent of the regulated release of interleukin-1 alpha from a cell.

CASP1, PANX1

GO:0050718

BP

positive regulation of interleukin-1 beta secretion

Any process that activates or increases the frequency, rate or extent of the regulated release of interleukin-1 beta from a cell.

CCL3, IFNAR1, CASP1, WNT5A, PANX1, PYCARD

GO:0050725

BP

positive regulation of interleukin-1 beta biosynthetic process

Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-1 beta.

EGR1

GO:0050726

BP

positive regulation of interleukin-1 alpha biosynthetic process

Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-1 alpha.

CCL20

GO:0050727

BP

regulation of inflammatory response

Any process that modulates the frequency, rate or extent of the inflammatory response, the immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents.

JAK2, BRD4, SEMA7A, AHSG, ESR1, ANXA1, LYN, IL1R1, SELE, TNFAIP3, TNFSF4, AGTR1, PTGS2, BCL6, CASP4, SLC7A2, ADAMTS12, XIAP, RELA, MTA1, BIRC3, NR1D2, ZYX, DUOXA1, DUOXA2, RICTOR, SETD6, PGLYRP2, MGLL, FANCD2, FOXP1, TBC1D23, SHPK, PYCARD

GO:0050728

BP

negative regulation of inflammatory response

Any process that stops, prevents, or reduces the frequency, rate or extent of the inflammatory response.

SOCS3, KLF4, SOCS5, ADA, APOA1, APOE, KRT1, SAA1, BCR, HGF, ETS1, PTPN2, NFKB1, TNFRSF1B, TNFAIP3, NT5E, RORA, PTGER4, CHRNA7, SERPINF1, SMAD3, TNFAIP6, TEK, PPARD, MVK, PRKCD, TYRO3, PPARA, ABR, NR1H3, MAPK7, ADIPOQ, PTGIS, CD276, GHSR, PBK, NR1H4, GPER1, VIMP, FEM1A, NDFIP1, C1QTNF3, WFDC1, MMP26, GHRL, RABGEF1

GO:0050729

BP

positive regulation of inflammatory response

Any process that activates or increases the frequency, rate or extent of the inflammatory response.

TLR4, MAPK13, TLR3, TLR2, JAK2, IL33, EGFR, AGT, LDLR, S100A8, SERPINE1, S100A9, LPL, CCL3, HSPD1, CCL4, CCL2, CCL5, PLA2G2A, ETS1, FABP4, ITGA2, ZP3, TGM2, TNFSF4, AGTR1, PTGER4, WNT5A, STAT5B, CCL8, IL1RL1, CD47, HYAL2, PLA2G7, IL18, CDK19, TRPV4, IL17RB, GPRC5B

GO:0050730

BP

regulation of peptidyl-tyrosine phosphorylation

Any process that modulates the frequency, rate or extent of the phosphorylation of peptidyl-tyrosine.

EGFR, PDGFA, ITGB2, IFNAR1, EFNA1, PPP2R5B, PDGFD, PDCL3, PDGFC

GO:0050731

BP

positive regulation of peptidyl-tyrosine phosphorylation

Any process that activates or increases the frequency, rate or extent of the phosphorylation of peptidyl-tyrosine.

HAX1, PLPP3, NRP1, RIPK2, JAK2, AGT, PDGFB, TGFB1, GH1, INS, IGF2, CD4, VTN, CD74, TP53, IGF1, ITGB3, IL6, ICAM1, CCK, ITGA5, IL6R, GHR, TDGF1, MIF, HGF, HCLS1, LIF, VEGFA, CD44, CD36, IL11, EFNA1, KITLG, FGF7, THBS4, SYK, VEGFC, EFNA5, CD81, NRG1, TNK2, CNTN1, PAK2, ENPP2, ANGPT1, STK11, ADIPOQ, RICTOR, CSPG4, ARHGEF2, MLST8, EHD4

GO:0050732

BP

negative regulation of peptidyl-tyrosine phosphorylation

Any process that stops, prevents, or reduces the frequency, rate or extent of the phosphorylation of peptidyl-tyrosine.

SPINK1, PRKCD, SFRP1, SAMSN1

GO:0050746

BP

regulation of lipoprotein metabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving lipoproteins, any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids.

DGAT2, LIPG

GO:0050747

BP

positive regulation of lipoprotein metabolic process

Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving lipoproteins, any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids.

PEMT

GO:0050748

BP

negative regulation of lipoprotein metabolic process

Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving lipoproteins, any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids.

ITGB3, ITGAV

GO:0050755

BP

chemokine metabolic process

The chemical reactions and pathways involving chemokines, any member of a family of small chemotactic cytokines; their name is derived from their ability to induce directed chemotaxis in nearby responsive cells. All chemokines possess a number of conserved cysteine residues involved in intramolecular disulfide bond formation. Some chemokines are considered pro-inflammatory and can be induced during an immune response to recruit cells of the immune system to a site of infection, while others are considered homeostatic and are involved in controlling the migration of cells during normal processes of tissue maintenance or development. Chemokines are found in all vertebrates, some viruses and some bacteria.

TREM1

GO:0050760

BP

negative regulation of thymidylate synthase biosynthetic process

Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of the enzyme thymidylate synthase.

APBB1

GO:0050764

BP

regulation of phagocytosis

Any process that modulates the frequency, rate or extent of phagocytosis, the process in which phagocytes engulf external particulate material.

ITGAV, FGR, SYK, SCARB1

GO:0050765

BP

negative regulation of phagocytosis

Any process that stops, prevents, or reduces the frequency, rate or extent of phagocytosis.

SNX3, TGFB1, CSK, PTEN, RACK1, ADIPOQ, SYT11

GO:0050766

BP

positive regulation of phagocytosis

Any process that activates or increases the frequency, rate or extent of phagocytosis.

TNF, IL1B, AHSG, MBL2, BCR, PTX3, CALR, SLC11A1, RAB27A, RAP1A, CD47, MERTK, ABR, GAS6, CAMK1D, DOCK2, PYCARD

GO:0050767

BP

regulation of neurogenesis

Any process that modulates the frequency, rate or extent of neurogenesis, the origin and formation of neurons.

ARNTL, HMGB2, CTNNB1, BCL6, YAP1, DOCK7, DLL4, CHD7

GO:0050768

BP

negative regulation of neurogenesis

Any process that stops, prevents, or reduces the frequency, rate or extent of neurogenesis, the origin and formation of neurons.

BRINP1, BMPR1A, NOTCH1, DYNLT1, PCM1, HOOK3, SORL1, ARHGEF2

GO:0050769

BP

positive regulation of neurogenesis

Any process that activates or increases the frequency, rate or extent of neurogenesis, the origin and formation of neurons.

WNT2, XRCC5, SERPINF1, STAR, NUMB, SPEN, GPER1, ZNF335

GO:0050770

BP

regulation of axonogenesis

Any process that modulates the frequency, rate or extent of axonogenesis, the generation of an axon, the long process of a neuron.

CHN1, EFNA1, EPHA4, SSH2, SSH3, KIF13B

GO:0050771

BP

negative regulation of axonogenesis

Any process that stops, prevents, or reduces the frequency, rate or extent of axonogenesis.

DAB1, NGFR, MAG, EPHB2, GDI1, PSEN1, ARHGDIA, PTEN, RHOA, PTK2, RUFY3, SYNGAP1, RTN4

GO:0050772

BP

positive regulation of axonogenesis

Any process that activates or increases the frequency, rate or extent of axonogenesis.

PLXNB2, SHOX2, SLIT2, NGF, NGFR, SKIL, ARHGDIA, RHOA, MAP2K1, TIAM1, STK11, NTRK2, ROBO2

GO:0050773

BP

regulation of dendrite development

Any process that modulates the frequency, rate or extent of dendrite development.

CDC20, DBN1, CAMK1D, RTN4IP1

GO:0050774

BP

negative regulation of dendrite morphogenesis

Any process that stops, prevents, or reduces the frequency, rate or extent of dendrite morphogenesis.

ID1, YWHAH, PPP3CA, NFATC4, TRPC6

GO:0050775

BP

positive regulation of dendrite morphogenesis

Any process that activates or increases the frequency, rate or extent of dendrite morphogenesis.

OBSL1, PTPRD, VAMP7, EPHA4, ILK, CUX1, CAPRIN1, CUL7, ANKRD27, RAB21