Search Geneontologies

Geneontologies

GO ID Ontology GO Term Term Definition Proteins

GO:0045626

BP

negative regulation of T-helper 1 cell differentiation

Any process that stops, prevents, or reduces the frequency, rate or extent of T-helper 1 cell differentiation.

TNFSF4, IL4R, JAK3

GO:0045627

BP

positive regulation of T-helper 1 cell differentiation

Any process that activates or increases the frequency, rate or extent of T-helper 1 cell differentiation.

RIPK2, SOCS5, ANXA1

GO:0045629

BP

negative regulation of T-helper 2 cell differentiation

Any process that stops, prevents, or reduces the frequency, rate or extent of T-helper 2 cell differentiation.

SOCS5, ANXA1, BCL6

GO:0045630

BP

positive regulation of T-helper 2 cell differentiation

Any process that activates or increases the frequency, rate or extent of T-helper 2 cell differentiation.

IL6, TNFSF4, IL4R, IL18

GO:0045634

BP

regulation of melanocyte differentiation

Any process that modulates the frequency, rate or extent of melanocyte differentiation.

GNA11, GNAQ

GO:0045636

BP

positive regulation of melanocyte differentiation

Any process that activates or increases the frequency, rate or extent of melanocyte differentiation.

ZEB2, BCL2, KITLG, ADAMTS20, ADAMTS9

GO:0045637

BP

regulation of myeloid cell differentiation

Any process that modulates the frequency, rate or extent of myeloid cell differentiation.

FAS, PURB, CSF3R

GO:0045638

BP

negative regulation of myeloid cell differentiation

Any process that stops, prevents, or reduces the frequency, rate or extent of myeloid cell differentiation.

MEIS1, CDK6, ZBTB16, RBM15

GO:0045639

BP

positive regulation of myeloid cell differentiation

Any process that activates or increases the frequency, rate or extent of myeloid cell differentiation.

LEP, JAG1

GO:0045645

BP

positive regulation of eosinophil differentiation

Any process that activates or increases the frequency, rate or extent of eosinophil differentiation.

TRIB1

GO:0045646

BP

regulation of erythrocyte differentiation

Any process that modulates the frequency, rate or extent of erythrocyte differentiation.

LYN, CDK6

GO:0045647

BP

negative regulation of erythrocyte differentiation

Any process that stops, prevents, or reduces the frequency, rate or extent of erythrocyte differentiation.

ZFP36, STAT5B, ZFP36L1, KLF13, MAFB

GO:0045648

BP

positive regulation of erythrocyte differentiation

Any process that activates or increases the frequency, rate or extent of erythrocyte differentiation.

FOXO3, KDM1A, ISG15, INHBA, ETS1, TAL1, HMGB2, ACVR2A, ARNT, ACVR1B, STAT5B, ID2, MAPK14, HIF1A, INPP5D, PRMT1

GO:0045650

BP

negative regulation of macrophage differentiation

Any process that stops, prevents, or reduces the frequency, rate or extent of macrophage differentiation.

INHA, INHBA, PTPN2, ADIPOQ

GO:0045651

BP

positive regulation of macrophage differentiation

Any process that activates or increases the frequency, rate or extent of macrophage differentiation.

PF4, RB1, HCLS1, LIF, PRKCA, ID2, FADD, RIPK1, CASP8, IL34, TRIB1

GO:0045652

BP

regulation of megakaryocyte differentiation

Any process that modulates the frequency, rate or extent of megakaryocyte differentiation.

EIF6, MEF2C, L3MBTL1

GO:0045653

BP

negative regulation of megakaryocyte differentiation

Any process that stops, prevents, or reduces the frequency, rate or extent of megakaryocyte differentiation.

PF4, HIST1H4A, GABPA, CIB1, PRMT1

GO:0045654

BP

positive regulation of megakaryocyte differentiation

Any process that activates or increases the frequency, rate or extent of megakaryocyte differentiation.

KDM1A, HMGB2

GO:0045655

BP

regulation of monocyte differentiation

Any process that modulates the frequency, rate or extent of monocyte differentiation.

FOXP1

GO:0045656

BP

negative regulation of monocyte differentiation

Any process that stops, prevents, or reduces the frequency, rate or extent of monocyte differentiation.

MYC, APCS, CDK6, INPP5D

GO:0045657

BP

positive regulation of monocyte differentiation

Any process that activates or increases the frequency, rate or extent of monocyte differentiation.

JUN, ZFP36L1, IL34

GO:0045659

BP

negative regulation of neutrophil differentiation

Any process that stops, prevents, or reduces the frequency, rate or extent of neutrophil differentiation.

INPP5D, TRIB1

GO:0045661

BP

regulation of myoblast differentiation

Any process that modulates the frequency, rate or extent of myoblast differentiation. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.

CAPN3, ZFP36L1

GO:0045662

BP

negative regulation of myoblast differentiation

Any process that stops, prevents, or reduces the frequency, rate or extent of myoblast differentiation. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.

MSTN, CXCL14, TGFB1, TNF, BMP4, DDIT3, NOTCH1, SOX9, SOX8, ID3, PPARD, IL18, MBNL3

GO:0045663

BP

positive regulation of myoblast differentiation

Any process that activates or increases the frequency, rate or extent of myoblast differentiation. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.

IGFBP3, BTG1, MEF2C, ILK, MAPK14, MAP3K5, PLCB1

GO:0045664

BP

regulation of neuron differentiation

Any process that modulates the frequency, rate or extent of neuron differentiation.

BIN1, NGF, YWHAH, ZFHX3, NREP, CASZ1, NLGN1

GO:0045665

BP

negative regulation of neuron differentiation

Any process that stops, prevents, or reduces the frequency, rate or extent of neuron differentiation.

MEIS1, HOXA2, FOXO3, APP, EIF4E, GLI3, CALR, PBX1, ID4, ASCL1, IRX3, JAG1, ID2, DIXDC1, MIB1, CNTN4, ASPM, CTDSP1, HMG20A, EIF4ENIF1, EIF2AK4, PRPF19

GO:0045666

BP

positive regulation of neuron differentiation

Any process that activates or increases the frequency, rate or extent of neuron differentiation.

SPAG9, BRINP1, DAB1, GLI2, FGFR1, BMP2, BMP4, TCF4, TCF3, TIMP2, ADRA2B, BMP6, ZEB1, ETV5, BCL6, NBL1, GDF5, ASCL1, RHOA, IRX3, MEF2C, MMD, NCOA1, DUOXA1, KCTD11, CYB5D2, NRCAM, TCF12, TLE6, ECT2, LIN28A, HEYL, GPRC5B, HMG20B, IMPACT, DNMT3B, NAP1L2, MAPK8IP3, TRPC6

GO:0045667

BP

regulation of osteoblast differentiation

Any process that modulates the frequency, rate or extent of osteoblast differentiation.

SNAI2, ESRRA, PRKACA, DDX5, FGFR2, PTK2

GO:0045668

BP

negative regulation of osteoblast differentiation

Any process that stops, prevents, or reduces the frequency, rate or extent of osteoblast differentiation.

HOXA2, LRP5, TNF, SKI, AREG, IGFBP5, ID1, NOTCH1, HDAC4, SMAD3, CDK6, ID2, ID3, PTCH1, NBR1, TWIST1, SFRP1, TRPM4, HDAC7, CITED1, LIMD1, NOCT, SUFU

GO:0045669

BP

positive regulation of osteoblast differentiation

Any process that activates or increases the frequency, rate or extent of osteoblast differentiation.

CLIC1, CYR61, IGF1, IL6, IL6R, GLI3, BMP2, BMP4, IFITM1, HGF, GJA1, JUND, CEBPB, BMP6, ACVR2A, CTNNB1, FBN2, BMPR1A, IL6ST, ID4, CEBPD, JAG1, GNAS, ACVR1, MEF2C, ILK, ACVR2B, BMPR2, RUNX2, PRKD1, SMAD1, GNAS, CD276, FAM20C, CTHRC1, SMAD5, PDLIM7

GO:0045670

BP

regulation of osteoclast differentiation

Any process that modulates the frequency, rate or extent of osteoclast differentiation.

MITF, FSHB, BGLAP, ESRRA, CEBPB, FSHR, FAM213A

GO:0045671

BP

negative regulation of osteoclast differentiation

Any process that stops, prevents, or reduces the frequency, rate or extent of osteoclast differentiation.

TLR4, TLR3, CCL3, PIK3R1, CTNNB1, FBN1, TOB2, CARTPT, SFRP1, LRRC17, TMEM178A, ZNF675, UBASH3B, INPP5D, MAFB

GO:0045672

BP

positive regulation of osteoclast differentiation

Any process that activates or increases the frequency, rate or extent of osteoclast differentiation.

TNFSF11, CA2, FOS, TNF, CREB1, GNAS, KLF10, GNAS, PPARGC1B

GO:0045682

BP

regulation of epidermis development

Any process that modulates the frequency, rate or extent of epidermis development.

NME2

GO:0045684

BP

positive regulation of epidermis development

Any process that activates or increases the frequency, rate or extent of epidermis development.

PPARD

GO:0045686

BP

negative regulation of glial cell differentiation

Any process that stops, prevents, or reduces the frequency, rate or extent of glia cell differentiation.

LIN28A

GO:0045713

BP

low-density lipoprotein particle receptor biosynthetic process

The chemical reactions and pathways resulting in the formation of low-density lipoprotein receptors, cell surface proteins that mediate the endocytosis of low-density lipoprotein particles by cells.

PPARG

GO:0045714

BP

regulation of low-density lipoprotein particle receptor biosynthetic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of low-density lipoprotein particle receptors.

FURIN

GO:0045715

BP

negative regulation of low-density lipoprotein particle receptor biosynthetic process

Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of low-density lipoprotein particle receptors.

ITGB3, ITGAV, ADIPOQ

GO:0045716

BP

positive regulation of low-density lipoprotein particle receptor biosynthetic process

Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of low-density lipoprotein receptors.

CNPY2

GO:0045717

BP

negative regulation of fatty acid biosynthetic process

Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of fatty acids.

INSIG1, ERLIN2, APOC1, APOC3, BRCA1, ACADVL, TRIB3

GO:0045719

BP

negative regulation of glycogen biosynthetic process

Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glycogen.

ENPP1, GSK3B, PASK, VIMP, INPP5K

GO:0045720

BP

negative regulation of integrin biosynthetic process

Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of integrins.

AR, TMEFF2

GO:0045721

BP

negative regulation of gluconeogenesis

Any process that stops, prevents, or reduces the frequency, rate or extent of gluconeogenesis.

INS, IL6, MST1, LEPR, CLK2, SIK1, ADIPOQ, SERPINA12, C1QTNF3

GO:0045722

BP

positive regulation of gluconeogenesis

Any process that activates or increases the frequency, rate or extent of gluconeogenesis.

PTPN2, ARPP19, PPARA, FOXO1, DGAT2, PPARGC1A

GO:0045723

BP

positive regulation of fatty acid biosynthetic process

Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of fatty acids.

APOA1, NR1H2, NR1H3, RGN, APOA5, MID1IP1

GO:0045724

BP

positive regulation of cilium assembly

Any process that activates or increases the frequency, rate or extent of the formation of a cilium.

HTT, CEP120, MNS1

GO:0045725

BP

positive regulation of glycogen biosynthetic process

Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glycogen.

PTH, INS, IGF2, IGF1, INSR, AKT1, AKT2, IRS1, EPM2AIP1, DYRK2, SORBS1, IRS2

GO:0045726

BP

positive regulation of integrin biosynthetic process

Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of integrins.

AR, TGFB2

GO:0045727

BP

positive regulation of translation

Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA.

DDX3X, ERBB2, IL6, NPM1, THBS1, CD28, CDK4, EEF2, ITGA2, BCL3, PTAFR, MAPK3, MAPK1, EIF6, RBM3, KRT17, FMR1, SOX4, CIRBP, HNRNPD, ELAVL1, PRR16, LARP1, RPS27L, GUF1, CPEB3, PASK, PINK1, POLDIP3, FAM129A, PAIP1, UPF3A, LIN28A, SAMD4A

GO:0045730

BP

respiratory burst

A phase of elevated metabolic activity, during which oxygen consumption increases; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals.

CYBB, CD55, PGAM1, NCF2, CD24, SLC11A1

GO:0045732

BP

positive regulation of protein catabolic process

Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.

AXIN1, PARK2, SEC22B, OAZ2, GJA1, TNFAIP3, APC, WNT5A, NSF, CDKN1B, SOX9, GSK3B, RAB7A, OAZ1, VCP, FOXO1, SNX1, CUL4B, MYLIP, SORL1, NEDD4L, BARD1, NDFIP1, SOX17, DACT1, PLK2, NDUFA13, GGA1, FZR1

GO:0045736

BP

negative regulation of cyclin-dependent protein serine/threonine kinase activity

Any process that stops, prevents, or reduces the frequency, rate or extent of cyclin-dependent protein serine/threonine kinase activity.

HEXIM1, LATS1, TNFAIP3, NR2F2, APC, CDKN1A, CDKN1B, PLK1, HHEX, KAT2B, LATS2

GO:0045737

BP

positive regulation of cyclin-dependent protein serine/threonine kinase activity

Any process that activates or increases the frequency, rate or extent of CDK activity.

CCNT1, CCNT2, PSMD10, PDGFB, CCND2, CCND3, CKS2, CDKN1B, CKS1B, PSRC1, PROX1, CCNL2, CDC6, CCNL1, MAPRE3

GO:0045739

BP

positive regulation of DNA repair

Any process that activates or increases the frequency, rate or extent of DNA repair.

EYA2, APBB1, RNF8, EYA4, EGFR, PCNA, H2AFX, BRCA1, BRCC3, CEBPG, TRIM28, UBE2V2, NPAS2

GO:0045740

BP

positive regulation of DNA replication

Any process that activates or increases the frequency, rate or extent of DNA replication.

EREG, EGFR, CST3, PDGFB, INS, PDGFA, IGF1, IL6, JUN, INSR, CDK1, NPM1, IGF1R, GLI2, PCNA, AREG, PDGFRA, ATF1, KITLG, CALR, DNA2, CDC42, RAC1, KCTD13, OBFC1, CACYBP, PDGFC

GO:0045741

BP

positive regulation of epidermal growth factor-activated receptor activity

Any process that activates or increases the frequency, rate or extent of EGF-activated receptor activity.

EREG, TGFA, ADORA1, ADAM17

GO:0045742

BP

positive regulation of epidermal growth factor receptor signaling pathway

Any process that activates or increases the frequency, rate or extent of epidermal growth factor receptor signaling pathway activity.

AGT, UBC, MMP9, AKT1, NUP62, RPS27A, UBA52, PLAUR, SOS1, AFAP1L2, ARAP1, GPER1, DOK1

GO:0045743

BP

positive regulation of fibroblast growth factor receptor signaling pathway

Any process that activates or increases the frequency, rate or extent of fibroblast growth factor receptor signaling pathway activity.

CTNNB1, DSTYK, PRKD2

GO:0045744

BP

negative regulation of G-protein coupled receptor protein signaling pathway

Any process that stops, prevents, or reduces the frequency, rate or extent of G-protein coupled receptor protein signaling pathway activity.

CXCL8, CCL5, YWHAB, RGS2, RGS4, CRY1, RPH3AL

GO:0045745

BP

positive regulation of G-protein coupled receptor protein signaling pathway

Any process that activates or increases the frequency, rate or extent of G-protein coupled receptor protein signaling pathway activity.

C3, DRD2, PHB, GPER1

GO:0045746

BP

negative regulation of Notch signaling pathway

Any process that stops, prevents, or reduces the frequency, rate or extent of the Notch signaling pathway.

BCL6, NUMB, MMP14, DLK1, DLX2, PEAR1, RITA1, CHAC1, DLL4, HEY1

GO:0045747

BP

positive regulation of Notch signaling pathway

Any process that activates or increases the frequency, rate or extent of the Notch signaling pathway.

ITGB1BP1, KIT, STAT3, NOTCH1, ASCL1, TSPAN5, JAG1, ERH, HES1, AAK1, TSPAN14, PDCD10, SLC35C2, DLL4

GO:0045759

BP

negative regulation of action potential

Any process that stops, prevents, or reduces the frequency, rate or extent of action potential creation, propagation or termination. This typically occurs via modulation of the activity or expression of voltage-gated ion channels.

CNR1

GO:0045760

BP

positive regulation of action potential

Any process that activates or increases the frequency, rate or extent of action potential creation, propagation or termination. This typically occurs via modulation of the activity or expression of voltage-gated ion channels.

ADRA1A

GO:0045762

BP

positive regulation of adenylate cyclase activity

Any process that activates or increases the frequency, rate or extent of adenylate cyclase activity.

TIMP2

GO:0045765

BP

regulation of angiogenesis

Any process that modulates the frequency, rate or extent of angiogenesis.

TSPAN12, KRT1, ERBB2, IL6, FGF2, HMOX1, RNH1, ETS1, EFNA1, SP100, CTNNB1, ID1, LEP, EMP2, MAPK7, ENPP2, SFRP1, HTATIP2, TNFRSF12A, PLXND1

GO:0045766

BP

positive regulation of angiogenesis

Any process that activates or increases angiogenesis.

ANGPT2, GREM1, PDCD6, DDAH1, C3, IL1A, IL1B, LRG1, HSPB1, CYBB, ITGB2, SERPINE1, PRKCB, THBS1, FGF2, HMOX1, CTSH, CXCL8, RRAS, ANXA3, C6, HGF, ETS1, VEGFA, PRKCA, XBP1, C5AR1, CXCR2, NOS3, ADM, CHI3L1, CHRNA7, TGFBR2, BRCA1, WNT5A, GATA4, PGF, VEGFC, BTG1, RHOB, RUNX1, TEK, SEMA5A, PRKD1, TWIST1, PTGIS, HIF1A, CYP1B1, CCBE1, MTDH, VASH2, AGGF1, GATA6, MYDGF, PRKD2, PDCL3, HIPK2, SPHK1, ERAP1

GO:0045769

BP

negative regulation of asymmetric cell division

Any process that stops, prevents, or reduces the frequency, rate or extent of asymmetric cell division.

ASPM

GO:0045773

BP

positive regulation of axon extension

Any process that activates or increases the frequency, rate or extent of axon extension.

SEMA7A, FN1, MAPT, MAP1B, GSK3B, RAB11A, NRG1, ILK, GOLGA4, TWF2, RUFY3, NDEL1, TNFRSF12A, MACF1, TRPV2

GO:0045776

BP

negative regulation of blood pressure

Any process in which the force of blood traveling through the circulatory system is decreased.

DRD2, CNR1, PTAFR, NOS3, ADORA1, GJA5, OPRL1, VEGFC, ABAT, PPARA, ADIPOQ, SCPEP1, MKKS, APLN

GO:0045777

BP

positive regulation of blood pressure

Any process in which the force of blood traveling through the circulatory system is increased.

AGT, CNR1, ADORA1, OXTR, ID2, ADIPOQ, CARTPT, OR51E2, F11R

GO:0045778

BP

positive regulation of ossification

Any process that activates or increases the frequency, rate or extent of bone formation.

BMP2, BMP4, WNT5A, TGFB2, ZBTB16, BMPR2, TOB2, NIPBL

GO:0045779

BP

negative regulation of bone resorption

Any process that stops, prevents, or reduces the frequency, rate or extent of bone resorption.

TNFRSF11B, IL6, IAPP, TNFAIP3, CSK, CARTPT, UBASH3B, INPP5D

GO:0045780

BP

positive regulation of bone resorption

Any process that activates or increases the frequency, rate or extent of bone resorption.

TNFSF11, EGFR, CA2, FSHB, TFRC, SPP1, MC4R, SYK, ADAM8, PPARGC1B

GO:0045785

BP

positive regulation of cell adhesion

Any process that activates or increases the frequency, rate or extent of cell adhesion.

RHOD, CYTH3, TNF, ERBB2, ITGAV, TPM1, SAA1, CCL5, VEGFA, PRKCA, ITGA2, TGM2, IL12A, MIP, CXCL12, ADAM8, C1QBP, STX4, PTPRJ, STX3, ANGPT1, FLCN, DUSP26, PRKD2, EPB41L4B, VAV3, ADGRG1

GO:0045786

BP

negative regulation of cell cycle

Any process that stops, prevents or reduces the rate or extent of progression through the cell cycle.

NUPR1, BRINP1, GMNN, TGFB1, INHA, INHBA, BMP2, BMP4, HPGD, NR4A1, PTGS2, PLA2G16, RHOB, CDK6, CDK5, ZBTB17, TP53BP2, RUNX3, PTPRK, RPS6KA2, PDCD4, LILRB1, TSPYL2

GO:0045787

BP

positive regulation of cell cycle

Any process that activates or increases the rate or extent of progression through the cell cycle.

BCL2L11, LRP6, FGFR1, CDK4, FOSL1, FGFR2, CALR, CDKN1B, ASCL1, PGGT1B, TGFB2, RPS15A, SRPK2, C6orf89, NR4A3, PROX1, CITED2, CCPG1

GO:0045792

BP

negative regulation of cell size

Any process that reduces cell size.

AKT1, RDX, PTEN, DEPTOR

GO:0045793

BP

positive regulation of cell size

Any process that increases cell size.

KDM1A, EDN1, HSP90AA1, HSP90AB1, CDK4, PRR16, RB1CC1

GO:0045794

BP

negative regulation of cell volume

Any process that decreases cell volume.

CLCN3, KCNMA1, ANO6

GO:0045795

BP

positive regulation of cell volume

Any process that increases cell volume.

SLC12A2

GO:0045796

BP

negative regulation of intestinal cholesterol absorption

Any process that stops, prevents, or reduces the frequency, rate or extent of uptake of cholesterol into the blood by absorption from the intestine.

ABCG8

GO:0045799

BP

positive regulation of chromatin assembly or disassembly

Any process that activates or increases the frequency, rate or extent of chromatin assembly or disassembly.

TAL1

GO:0045806

BP

negative regulation of endocytosis

Any process that stops, prevents, or reduces the frequency, rate or extent of endocytosis.

LGALS3, MTMR2, PRKD1, LILRB1, SNX33, PACSIN1

GO:0045807

BP

positive regulation of endocytosis

Any process that activates or increases the frequency, rate or extent of endocytosis.

FLOT1, CD14, SNCA, WNT5A, ARF1, DAB2, CBLL1, MIB1, NEDD4L, TFR2

GO:0045814

BP

negative regulation of gene expression, epigenetic

Any epigenetic process that stops, prevents or reduces the rate of gene expression.

H2AFY, DNMT1, HIST1H4A, HIST1H3D, H3F3A, RBBP4, SUZ12, EZH2, PHF19, EPC1, H2AFY2, DNMT3B, MTF2

GO:0045815

BP

positive regulation of gene expression, epigenetic

Any epigenetic process that activates or increases the rate of gene expression.

MYO1C, POLR1C, CD3EAP, SMARCA5, H2AFY, POLR1A, POLR2E, DEK, POLR2K, ACTB, HIST1H4A, POLR2L, HIST1H3D, H3F3A, EP300, TAF1C, TAF1A, TAF1B, KAT2B, WBP2, MYBBP1A, POLR1E, TAF1D, ZNRD1, BAZ1B, POLR1D

GO:0045818

BP

negative regulation of glycogen catabolic process

Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glycogen.

INS

GO:0045820

BP

negative regulation of glycolytic process

Any process that stops, prevents, or reduces the frequency, rate or extent of glycolysis.

FBP1, STAT3, HDAC4, PPARA, DDIT4, PPARGC1A

GO:0045821

BP

positive regulation of glycolytic process

Any process that activates or increases the frequency, rate or extent of glycolysis.

INS, IGF1, INSR, ARNT, PRKAA2, HIF1A

GO:0045822

BP

negative regulation of heart contraction

Any process that stops, prevents, or reduces the frequency, rate or extent of heart contraction.

JAK2, ATP2A2, ATP1A2, PDE4D

GO:0045823

BP

positive regulation of heart contraction

Any process that activates or increases the frequency, rate or extent of heart contraction.

TGFB2

GO:0045824

BP

negative regulation of innate immune response

Any process that stops, prevents, or reduces the frequency, rate or extent of the innate immune response.

TRAFD1, DRD2, TNFAIP3, TYRO3, NMI, IFI16, IRAK3

GO:0045830

BP

positive regulation of isotype switching

Any process that activates or increases the frequency, rate or extent of isotype switching.

TFRC, UNG, MSH6, EXOSC6, EXOSC3

GO:0045833

BP

negative regulation of lipid metabolic process

Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving lipids.

IL1B, APOC1, APOC3

GO:0045835

BP

negative regulation of meiotic nuclear division

Any process that stops, prevents, or reduces the frequency, rate or extent of meiosis.

PRKAR1A, LIF, RPS6KA2, FBXO5

GO:0045836

BP

positive regulation of meiotic nuclear division

Any process that activates or increases the frequency, rate or extent of meiosis.

WNT5A, SIRT2

GO:0045837

BP

negative regulation of membrane potential

Any process that stops, prevents, or reduces the frequency, rate or extent of establishment or extent of a membrane potential, the electric potential existing across any membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane.

IL6, BNIP3