GO ID |
Ontology |
GO Term |
Term Definition |
Proteins |
GO:0045626
|
BP
|
negative regulation of T-helper 1 cell differentiation
|
Any process that stops, prevents, or reduces the frequency, rate or extent of T-helper 1 cell differentiation.
|
TNFSF4,
IL4R,
JAK3
|
GO:0045627
|
BP
|
positive regulation of T-helper 1 cell differentiation
|
Any process that activates or increases the frequency, rate or extent of T-helper 1 cell differentiation.
|
RIPK2,
SOCS5,
ANXA1
|
GO:0045629
|
BP
|
negative regulation of T-helper 2 cell differentiation
|
Any process that stops, prevents, or reduces the frequency, rate or extent of T-helper 2 cell differentiation.
|
SOCS5,
ANXA1,
BCL6
|
GO:0045630
|
BP
|
positive regulation of T-helper 2 cell differentiation
|
Any process that activates or increases the frequency, rate or extent of T-helper 2 cell differentiation.
|
IL6,
TNFSF4,
IL4R,
IL18
|
GO:0045634
|
BP
|
regulation of melanocyte differentiation
|
Any process that modulates the frequency, rate or extent of melanocyte differentiation.
|
GNA11,
GNAQ
|
GO:0045636
|
BP
|
positive regulation of melanocyte differentiation
|
Any process that activates or increases the frequency, rate or extent of melanocyte differentiation.
|
ZEB2,
BCL2,
KITLG,
ADAMTS20,
ADAMTS9
|
GO:0045637
|
BP
|
regulation of myeloid cell differentiation
|
Any process that modulates the frequency, rate or extent of myeloid cell differentiation.
|
FAS,
PURB,
CSF3R
|
GO:0045638
|
BP
|
negative regulation of myeloid cell differentiation
|
Any process that stops, prevents, or reduces the frequency, rate or extent of myeloid cell differentiation.
|
MEIS1,
CDK6,
ZBTB16,
RBM15
|
GO:0045639
|
BP
|
positive regulation of myeloid cell differentiation
|
Any process that activates or increases the frequency, rate or extent of myeloid cell differentiation.
|
LEP,
JAG1
|
GO:0045645
|
BP
|
positive regulation of eosinophil differentiation
|
Any process that activates or increases the frequency, rate or extent of eosinophil differentiation.
|
TRIB1
|
GO:0045646
|
BP
|
regulation of erythrocyte differentiation
|
Any process that modulates the frequency, rate or extent of erythrocyte differentiation.
|
LYN,
CDK6
|
GO:0045647
|
BP
|
negative regulation of erythrocyte differentiation
|
Any process that stops, prevents, or reduces the frequency, rate or extent of erythrocyte differentiation.
|
ZFP36,
STAT5B,
ZFP36L1,
KLF13,
MAFB
|
GO:0045648
|
BP
|
positive regulation of erythrocyte differentiation
|
Any process that activates or increases the frequency, rate or extent of erythrocyte differentiation.
|
FOXO3,
KDM1A,
ISG15,
INHBA,
ETS1,
TAL1,
HMGB2,
ACVR2A,
ARNT,
ACVR1B,
STAT5B,
ID2,
MAPK14,
HIF1A,
INPP5D,
PRMT1
|
GO:0045650
|
BP
|
negative regulation of macrophage differentiation
|
Any process that stops, prevents, or reduces the frequency, rate or extent of macrophage differentiation.
|
INHA,
INHBA,
PTPN2,
ADIPOQ
|
GO:0045651
|
BP
|
positive regulation of macrophage differentiation
|
Any process that activates or increases the frequency, rate or extent of macrophage differentiation.
|
PF4,
RB1,
HCLS1,
LIF,
PRKCA,
ID2,
FADD,
RIPK1,
CASP8,
IL34,
TRIB1
|
GO:0045652
|
BP
|
regulation of megakaryocyte differentiation
|
Any process that modulates the frequency, rate or extent of megakaryocyte differentiation.
|
EIF6,
MEF2C,
L3MBTL1
|
GO:0045653
|
BP
|
negative regulation of megakaryocyte differentiation
|
Any process that stops, prevents, or reduces the frequency, rate or extent of megakaryocyte differentiation.
|
PF4,
HIST1H4A,
GABPA,
CIB1,
PRMT1
|
GO:0045654
|
BP
|
positive regulation of megakaryocyte differentiation
|
Any process that activates or increases the frequency, rate or extent of megakaryocyte differentiation.
|
KDM1A,
HMGB2
|
GO:0045655
|
BP
|
regulation of monocyte differentiation
|
Any process that modulates the frequency, rate or extent of monocyte differentiation.
|
FOXP1
|
GO:0045656
|
BP
|
negative regulation of monocyte differentiation
|
Any process that stops, prevents, or reduces the frequency, rate or extent of monocyte differentiation.
|
MYC,
APCS,
CDK6,
INPP5D
|
GO:0045657
|
BP
|
positive regulation of monocyte differentiation
|
Any process that activates or increases the frequency, rate or extent of monocyte differentiation.
|
JUN,
ZFP36L1,
IL34
|
GO:0045659
|
BP
|
negative regulation of neutrophil differentiation
|
Any process that stops, prevents, or reduces the frequency, rate or extent of neutrophil differentiation.
|
INPP5D,
TRIB1
|
GO:0045661
|
BP
|
regulation of myoblast differentiation
|
Any process that modulates the frequency, rate or extent of myoblast differentiation. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.
|
CAPN3,
ZFP36L1
|
GO:0045662
|
BP
|
negative regulation of myoblast differentiation
|
Any process that stops, prevents, or reduces the frequency, rate or extent of myoblast differentiation. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.
|
MSTN,
CXCL14,
TGFB1,
TNF,
BMP4,
DDIT3,
NOTCH1,
SOX9,
SOX8,
ID3,
PPARD,
IL18,
MBNL3
|
GO:0045663
|
BP
|
positive regulation of myoblast differentiation
|
Any process that activates or increases the frequency, rate or extent of myoblast differentiation. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.
|
IGFBP3,
BTG1,
MEF2C,
ILK,
MAPK14,
MAP3K5,
PLCB1
|
GO:0045664
|
BP
|
regulation of neuron differentiation
|
Any process that modulates the frequency, rate or extent of neuron differentiation.
|
BIN1,
NGF,
YWHAH,
ZFHX3,
NREP,
CASZ1,
NLGN1
|
GO:0045665
|
BP
|
negative regulation of neuron differentiation
|
Any process that stops, prevents, or reduces the frequency, rate or extent of neuron differentiation.
|
MEIS1,
HOXA2,
FOXO3,
APP,
EIF4E,
GLI3,
CALR,
PBX1,
ID4,
ASCL1,
IRX3,
JAG1,
ID2,
DIXDC1,
MIB1,
CNTN4,
ASPM,
CTDSP1,
HMG20A,
EIF4ENIF1,
EIF2AK4,
PRPF19
|
GO:0045666
|
BP
|
positive regulation of neuron differentiation
|
Any process that activates or increases the frequency, rate or extent of neuron differentiation.
|
SPAG9,
BRINP1,
DAB1,
GLI2,
FGFR1,
BMP2,
BMP4,
TCF4,
TCF3,
TIMP2,
ADRA2B,
BMP6,
ZEB1,
ETV5,
BCL6,
NBL1,
GDF5,
ASCL1,
RHOA,
IRX3,
MEF2C,
MMD,
NCOA1,
DUOXA1,
KCTD11,
CYB5D2,
NRCAM,
TCF12,
TLE6,
ECT2,
LIN28A,
HEYL,
GPRC5B,
HMG20B,
IMPACT,
DNMT3B,
NAP1L2,
MAPK8IP3,
TRPC6
|
GO:0045667
|
BP
|
regulation of osteoblast differentiation
|
Any process that modulates the frequency, rate or extent of osteoblast differentiation.
|
SNAI2,
ESRRA,
PRKACA,
DDX5,
FGFR2,
PTK2
|
GO:0045668
|
BP
|
negative regulation of osteoblast differentiation
|
Any process that stops, prevents, or reduces the frequency, rate or extent of osteoblast differentiation.
|
HOXA2,
LRP5,
TNF,
SKI,
AREG,
IGFBP5,
ID1,
NOTCH1,
HDAC4,
SMAD3,
CDK6,
ID2,
ID3,
PTCH1,
NBR1,
TWIST1,
SFRP1,
TRPM4,
HDAC7,
CITED1,
LIMD1,
NOCT,
SUFU
|
GO:0045669
|
BP
|
positive regulation of osteoblast differentiation
|
Any process that activates or increases the frequency, rate or extent of osteoblast differentiation.
|
CLIC1,
CYR61,
IGF1,
IL6,
IL6R,
GLI3,
BMP2,
BMP4,
IFITM1,
HGF,
GJA1,
JUND,
CEBPB,
BMP6,
ACVR2A,
CTNNB1,
FBN2,
BMPR1A,
IL6ST,
ID4,
CEBPD,
JAG1,
GNAS,
ACVR1,
MEF2C,
ILK,
ACVR2B,
BMPR2,
RUNX2,
PRKD1,
SMAD1,
GNAS,
CD276,
FAM20C,
CTHRC1,
SMAD5,
PDLIM7
|
GO:0045670
|
BP
|
regulation of osteoclast differentiation
|
Any process that modulates the frequency, rate or extent of osteoclast differentiation.
|
MITF,
FSHB,
BGLAP,
ESRRA,
CEBPB,
FSHR,
FAM213A
|
GO:0045671
|
BP
|
negative regulation of osteoclast differentiation
|
Any process that stops, prevents, or reduces the frequency, rate or extent of osteoclast differentiation.
|
TLR4,
TLR3,
CCL3,
PIK3R1,
CTNNB1,
FBN1,
TOB2,
CARTPT,
SFRP1,
LRRC17,
TMEM178A,
ZNF675,
UBASH3B,
INPP5D,
MAFB
|
GO:0045672
|
BP
|
positive regulation of osteoclast differentiation
|
Any process that activates or increases the frequency, rate or extent of osteoclast differentiation.
|
TNFSF11,
CA2,
FOS,
TNF,
CREB1,
GNAS,
KLF10,
GNAS,
PPARGC1B
|
GO:0045682
|
BP
|
regulation of epidermis development
|
Any process that modulates the frequency, rate or extent of epidermis development.
|
NME2
|
GO:0045684
|
BP
|
positive regulation of epidermis development
|
Any process that activates or increases the frequency, rate or extent of epidermis development.
|
PPARD
|
GO:0045686
|
BP
|
negative regulation of glial cell differentiation
|
Any process that stops, prevents, or reduces the frequency, rate or extent of glia cell differentiation.
|
LIN28A
|
GO:0045713
|
BP
|
low-density lipoprotein particle receptor biosynthetic process
|
The chemical reactions and pathways resulting in the formation of low-density lipoprotein receptors, cell surface proteins that mediate the endocytosis of low-density lipoprotein particles by cells.
|
PPARG
|
GO:0045714
|
BP
|
regulation of low-density lipoprotein particle receptor biosynthetic process
|
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of low-density lipoprotein particle receptors.
|
FURIN
|
GO:0045715
|
BP
|
negative regulation of low-density lipoprotein particle receptor biosynthetic process
|
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of low-density lipoprotein particle receptors.
|
ITGB3,
ITGAV,
ADIPOQ
|
GO:0045716
|
BP
|
positive regulation of low-density lipoprotein particle receptor biosynthetic process
|
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of low-density lipoprotein receptors.
|
CNPY2
|
GO:0045717
|
BP
|
negative regulation of fatty acid biosynthetic process
|
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of fatty acids.
|
INSIG1,
ERLIN2,
APOC1,
APOC3,
BRCA1,
ACADVL,
TRIB3
|
GO:0045719
|
BP
|
negative regulation of glycogen biosynthetic process
|
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glycogen.
|
ENPP1,
GSK3B,
PASK,
VIMP,
INPP5K
|
GO:0045720
|
BP
|
negative regulation of integrin biosynthetic process
|
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of integrins.
|
AR,
TMEFF2
|
GO:0045721
|
BP
|
negative regulation of gluconeogenesis
|
Any process that stops, prevents, or reduces the frequency, rate or extent of gluconeogenesis.
|
INS,
IL6,
MST1,
LEPR,
CLK2,
SIK1,
ADIPOQ,
SERPINA12,
C1QTNF3
|
GO:0045722
|
BP
|
positive regulation of gluconeogenesis
|
Any process that activates or increases the frequency, rate or extent of gluconeogenesis.
|
PTPN2,
ARPP19,
PPARA,
FOXO1,
DGAT2,
PPARGC1A
|
GO:0045723
|
BP
|
positive regulation of fatty acid biosynthetic process
|
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of fatty acids.
|
APOA1,
NR1H2,
NR1H3,
RGN,
APOA5,
MID1IP1
|
GO:0045724
|
BP
|
positive regulation of cilium assembly
|
Any process that activates or increases the frequency, rate or extent of the formation of a cilium.
|
HTT,
CEP120,
MNS1
|
GO:0045725
|
BP
|
positive regulation of glycogen biosynthetic process
|
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glycogen.
|
PTH,
INS,
IGF2,
IGF1,
INSR,
AKT1,
AKT2,
IRS1,
EPM2AIP1,
DYRK2,
SORBS1,
IRS2
|
GO:0045726
|
BP
|
positive regulation of integrin biosynthetic process
|
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of integrins.
|
AR,
TGFB2
|
GO:0045727
|
BP
|
positive regulation of translation
|
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA.
|
DDX3X,
ERBB2,
IL6,
NPM1,
THBS1,
CD28,
CDK4,
EEF2,
ITGA2,
BCL3,
PTAFR,
MAPK3,
MAPK1,
EIF6,
RBM3,
KRT17,
FMR1,
SOX4,
CIRBP,
HNRNPD,
ELAVL1,
PRR16,
LARP1,
RPS27L,
GUF1,
CPEB3,
PASK,
PINK1,
POLDIP3,
FAM129A,
PAIP1,
UPF3A,
LIN28A,
SAMD4A
|
GO:0045730
|
BP
|
respiratory burst
|
A phase of elevated metabolic activity, during which oxygen consumption increases; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals.
|
CYBB,
CD55,
PGAM1,
NCF2,
CD24,
SLC11A1
|
GO:0045732
|
BP
|
positive regulation of protein catabolic process
|
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.
|
AXIN1,
PARK2,
SEC22B,
OAZ2,
GJA1,
TNFAIP3,
APC,
WNT5A,
NSF,
CDKN1B,
SOX9,
GSK3B,
RAB7A,
OAZ1,
VCP,
FOXO1,
SNX1,
CUL4B,
MYLIP,
SORL1,
NEDD4L,
BARD1,
NDFIP1,
SOX17,
DACT1,
PLK2,
NDUFA13,
GGA1,
FZR1
|
GO:0045736
|
BP
|
negative regulation of cyclin-dependent protein serine/threonine kinase activity
|
Any process that stops, prevents, or reduces the frequency, rate or extent of cyclin-dependent protein serine/threonine kinase activity.
|
HEXIM1,
LATS1,
TNFAIP3,
NR2F2,
APC,
CDKN1A,
CDKN1B,
PLK1,
HHEX,
KAT2B,
LATS2
|
GO:0045737
|
BP
|
positive regulation of cyclin-dependent protein serine/threonine kinase activity
|
Any process that activates or increases the frequency, rate or extent of CDK activity.
|
CCNT1,
CCNT2,
PSMD10,
PDGFB,
CCND2,
CCND3,
CKS2,
CDKN1B,
CKS1B,
PSRC1,
PROX1,
CCNL2,
CDC6,
CCNL1,
MAPRE3
|
GO:0045739
|
BP
|
positive regulation of DNA repair
|
Any process that activates or increases the frequency, rate or extent of DNA repair.
|
EYA2,
APBB1,
RNF8,
EYA4,
EGFR,
PCNA,
H2AFX,
BRCA1,
BRCC3,
CEBPG,
TRIM28,
UBE2V2,
NPAS2
|
GO:0045740
|
BP
|
positive regulation of DNA replication
|
Any process that activates or increases the frequency, rate or extent of DNA replication.
|
EREG,
EGFR,
CST3,
PDGFB,
INS,
PDGFA,
IGF1,
IL6,
JUN,
INSR,
CDK1,
NPM1,
IGF1R,
GLI2,
PCNA,
AREG,
PDGFRA,
ATF1,
KITLG,
CALR,
DNA2,
CDC42,
RAC1,
KCTD13,
OBFC1,
CACYBP,
PDGFC
|
GO:0045741
|
BP
|
positive regulation of epidermal growth factor-activated receptor activity
|
Any process that activates or increases the frequency, rate or extent of EGF-activated receptor activity.
|
EREG,
TGFA,
ADORA1,
ADAM17
|
GO:0045742
|
BP
|
positive regulation of epidermal growth factor receptor signaling pathway
|
Any process that activates or increases the frequency, rate or extent of epidermal growth factor receptor signaling pathway activity.
|
AGT,
UBC,
MMP9,
AKT1,
NUP62,
RPS27A,
UBA52,
PLAUR,
SOS1,
AFAP1L2,
ARAP1,
GPER1,
DOK1
|
GO:0045743
|
BP
|
positive regulation of fibroblast growth factor receptor signaling pathway
|
Any process that activates or increases the frequency, rate or extent of fibroblast growth factor receptor signaling pathway activity.
|
CTNNB1,
DSTYK,
PRKD2
|
GO:0045744
|
BP
|
negative regulation of G-protein coupled receptor protein signaling pathway
|
Any process that stops, prevents, or reduces the frequency, rate or extent of G-protein coupled receptor protein signaling pathway activity.
|
CXCL8,
CCL5,
YWHAB,
RGS2,
RGS4,
CRY1,
RPH3AL
|
GO:0045745
|
BP
|
positive regulation of G-protein coupled receptor protein signaling pathway
|
Any process that activates or increases the frequency, rate or extent of G-protein coupled receptor protein signaling pathway activity.
|
C3,
DRD2,
PHB,
GPER1
|
GO:0045746
|
BP
|
negative regulation of Notch signaling pathway
|
Any process that stops, prevents, or reduces the frequency, rate or extent of the Notch signaling pathway.
|
BCL6,
NUMB,
MMP14,
DLK1,
DLX2,
PEAR1,
RITA1,
CHAC1,
DLL4,
HEY1
|
GO:0045747
|
BP
|
positive regulation of Notch signaling pathway
|
Any process that activates or increases the frequency, rate or extent of the Notch signaling pathway.
|
ITGB1BP1,
KIT,
STAT3,
NOTCH1,
ASCL1,
TSPAN5,
JAG1,
ERH,
HES1,
AAK1,
TSPAN14,
PDCD10,
SLC35C2,
DLL4
|
GO:0045759
|
BP
|
negative regulation of action potential
|
Any process that stops, prevents, or reduces the frequency, rate or extent of action potential creation, propagation or termination. This typically occurs via modulation of the activity or expression of voltage-gated ion channels.
|
CNR1
|
GO:0045760
|
BP
|
positive regulation of action potential
|
Any process that activates or increases the frequency, rate or extent of action potential creation, propagation or termination. This typically occurs via modulation of the activity or expression of voltage-gated ion channels.
|
ADRA1A
|
GO:0045762
|
BP
|
positive regulation of adenylate cyclase activity
|
Any process that activates or increases the frequency, rate or extent of adenylate cyclase activity.
|
TIMP2
|
GO:0045765
|
BP
|
regulation of angiogenesis
|
Any process that modulates the frequency, rate or extent of angiogenesis.
|
TSPAN12,
KRT1,
ERBB2,
IL6,
FGF2,
HMOX1,
RNH1,
ETS1,
EFNA1,
SP100,
CTNNB1,
ID1,
LEP,
EMP2,
MAPK7,
ENPP2,
SFRP1,
HTATIP2,
TNFRSF12A,
PLXND1
|
GO:0045766
|
BP
|
positive regulation of angiogenesis
|
Any process that activates or increases angiogenesis.
|
ANGPT2,
GREM1,
PDCD6,
DDAH1,
C3,
IL1A,
IL1B,
LRG1,
HSPB1,
CYBB,
ITGB2,
SERPINE1,
PRKCB,
THBS1,
FGF2,
HMOX1,
CTSH,
CXCL8,
RRAS,
ANXA3,
C6,
HGF,
ETS1,
VEGFA,
PRKCA,
XBP1,
C5AR1,
CXCR2,
NOS3,
ADM,
CHI3L1,
CHRNA7,
TGFBR2,
BRCA1,
WNT5A,
GATA4,
PGF,
VEGFC,
BTG1,
RHOB,
RUNX1,
TEK,
SEMA5A,
PRKD1,
TWIST1,
PTGIS,
HIF1A,
CYP1B1,
CCBE1,
MTDH,
VASH2,
AGGF1,
GATA6,
MYDGF,
PRKD2,
PDCL3,
HIPK2,
SPHK1,
ERAP1
|
GO:0045769
|
BP
|
negative regulation of asymmetric cell division
|
Any process that stops, prevents, or reduces the frequency, rate or extent of asymmetric cell division.
|
ASPM
|
GO:0045773
|
BP
|
positive regulation of axon extension
|
Any process that activates or increases the frequency, rate or extent of axon extension.
|
SEMA7A,
FN1,
MAPT,
MAP1B,
GSK3B,
RAB11A,
NRG1,
ILK,
GOLGA4,
TWF2,
RUFY3,
NDEL1,
TNFRSF12A,
MACF1,
TRPV2
|
GO:0045776
|
BP
|
negative regulation of blood pressure
|
Any process in which the force of blood traveling through the circulatory system is decreased.
|
DRD2,
CNR1,
PTAFR,
NOS3,
ADORA1,
GJA5,
OPRL1,
VEGFC,
ABAT,
PPARA,
ADIPOQ,
SCPEP1,
MKKS,
APLN
|
GO:0045777
|
BP
|
positive regulation of blood pressure
|
Any process in which the force of blood traveling through the circulatory system is increased.
|
AGT,
CNR1,
ADORA1,
OXTR,
ID2,
ADIPOQ,
CARTPT,
OR51E2,
F11R
|
GO:0045778
|
BP
|
positive regulation of ossification
|
Any process that activates or increases the frequency, rate or extent of bone formation.
|
BMP2,
BMP4,
WNT5A,
TGFB2,
ZBTB16,
BMPR2,
TOB2,
NIPBL
|
GO:0045779
|
BP
|
negative regulation of bone resorption
|
Any process that stops, prevents, or reduces the frequency, rate or extent of bone resorption.
|
TNFRSF11B,
IL6,
IAPP,
TNFAIP3,
CSK,
CARTPT,
UBASH3B,
INPP5D
|
GO:0045780
|
BP
|
positive regulation of bone resorption
|
Any process that activates or increases the frequency, rate or extent of bone resorption.
|
TNFSF11,
EGFR,
CA2,
FSHB,
TFRC,
SPP1,
MC4R,
SYK,
ADAM8,
PPARGC1B
|
GO:0045785
|
BP
|
positive regulation of cell adhesion
|
Any process that activates or increases the frequency, rate or extent of cell adhesion.
|
RHOD,
CYTH3,
TNF,
ERBB2,
ITGAV,
TPM1,
SAA1,
CCL5,
VEGFA,
PRKCA,
ITGA2,
TGM2,
IL12A,
MIP,
CXCL12,
ADAM8,
C1QBP,
STX4,
PTPRJ,
STX3,
ANGPT1,
FLCN,
DUSP26,
PRKD2,
EPB41L4B,
VAV3,
ADGRG1
|
GO:0045786
|
BP
|
negative regulation of cell cycle
|
Any process that stops, prevents or reduces the rate or extent of progression through the cell cycle.
|
NUPR1,
BRINP1,
GMNN,
TGFB1,
INHA,
INHBA,
BMP2,
BMP4,
HPGD,
NR4A1,
PTGS2,
PLA2G16,
RHOB,
CDK6,
CDK5,
ZBTB17,
TP53BP2,
RUNX3,
PTPRK,
RPS6KA2,
PDCD4,
LILRB1,
TSPYL2
|
GO:0045787
|
BP
|
positive regulation of cell cycle
|
Any process that activates or increases the rate or extent of progression through the cell cycle.
|
BCL2L11,
LRP6,
FGFR1,
CDK4,
FOSL1,
FGFR2,
CALR,
CDKN1B,
ASCL1,
PGGT1B,
TGFB2,
RPS15A,
SRPK2,
C6orf89,
NR4A3,
PROX1,
CITED2,
CCPG1
|
GO:0045792
|
BP
|
negative regulation of cell size
|
Any process that reduces cell size.
|
AKT1,
RDX,
PTEN,
DEPTOR
|
GO:0045793
|
BP
|
positive regulation of cell size
|
Any process that increases cell size.
|
KDM1A,
EDN1,
HSP90AA1,
HSP90AB1,
CDK4,
PRR16,
RB1CC1
|
GO:0045794
|
BP
|
negative regulation of cell volume
|
Any process that decreases cell volume.
|
CLCN3,
KCNMA1,
ANO6
|
GO:0045795
|
BP
|
positive regulation of cell volume
|
Any process that increases cell volume.
|
SLC12A2
|
GO:0045796
|
BP
|
negative regulation of intestinal cholesterol absorption
|
Any process that stops, prevents, or reduces the frequency, rate or extent of uptake of cholesterol into the blood by absorption from the intestine.
|
ABCG8
|
GO:0045799
|
BP
|
positive regulation of chromatin assembly or disassembly
|
Any process that activates or increases the frequency, rate or extent of chromatin assembly or disassembly.
|
TAL1
|
GO:0045806
|
BP
|
negative regulation of endocytosis
|
Any process that stops, prevents, or reduces the frequency, rate or extent of endocytosis.
|
LGALS3,
MTMR2,
PRKD1,
LILRB1,
SNX33,
PACSIN1
|
GO:0045807
|
BP
|
positive regulation of endocytosis
|
Any process that activates or increases the frequency, rate or extent of endocytosis.
|
FLOT1,
CD14,
SNCA,
WNT5A,
ARF1,
DAB2,
CBLL1,
MIB1,
NEDD4L,
TFR2
|
GO:0045814
|
BP
|
negative regulation of gene expression, epigenetic
|
Any epigenetic process that stops, prevents or reduces the rate of gene expression.
|
H2AFY,
DNMT1,
HIST1H4A,
HIST1H3D,
H3F3A,
RBBP4,
SUZ12,
EZH2,
PHF19,
EPC1,
H2AFY2,
DNMT3B,
MTF2
|
GO:0045815
|
BP
|
positive regulation of gene expression, epigenetic
|
Any epigenetic process that activates or increases the rate of gene expression.
|
MYO1C,
POLR1C,
CD3EAP,
SMARCA5,
H2AFY,
POLR1A,
POLR2E,
DEK,
POLR2K,
ACTB,
HIST1H4A,
POLR2L,
HIST1H3D,
H3F3A,
EP300,
TAF1C,
TAF1A,
TAF1B,
KAT2B,
WBP2,
MYBBP1A,
POLR1E,
TAF1D,
ZNRD1,
BAZ1B,
POLR1D
|
GO:0045818
|
BP
|
negative regulation of glycogen catabolic process
|
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glycogen.
|
INS
|
GO:0045820
|
BP
|
negative regulation of glycolytic process
|
Any process that stops, prevents, or reduces the frequency, rate or extent of glycolysis.
|
FBP1,
STAT3,
HDAC4,
PPARA,
DDIT4,
PPARGC1A
|
GO:0045821
|
BP
|
positive regulation of glycolytic process
|
Any process that activates or increases the frequency, rate or extent of glycolysis.
|
INS,
IGF1,
INSR,
ARNT,
PRKAA2,
HIF1A
|
GO:0045822
|
BP
|
negative regulation of heart contraction
|
Any process that stops, prevents, or reduces the frequency, rate or extent of heart contraction.
|
JAK2,
ATP2A2,
ATP1A2,
PDE4D
|
GO:0045823
|
BP
|
positive regulation of heart contraction
|
Any process that activates or increases the frequency, rate or extent of heart contraction.
|
TGFB2
|
GO:0045824
|
BP
|
negative regulation of innate immune response
|
Any process that stops, prevents, or reduces the frequency, rate or extent of the innate immune response.
|
TRAFD1,
DRD2,
TNFAIP3,
TYRO3,
NMI,
IFI16,
IRAK3
|
GO:0045830
|
BP
|
positive regulation of isotype switching
|
Any process that activates or increases the frequency, rate or extent of isotype switching.
|
TFRC,
UNG,
MSH6,
EXOSC6,
EXOSC3
|
GO:0045833
|
BP
|
negative regulation of lipid metabolic process
|
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving lipids.
|
IL1B,
APOC1,
APOC3
|
GO:0045835
|
BP
|
negative regulation of meiotic nuclear division
|
Any process that stops, prevents, or reduces the frequency, rate or extent of meiosis.
|
PRKAR1A,
LIF,
RPS6KA2,
FBXO5
|
GO:0045836
|
BP
|
positive regulation of meiotic nuclear division
|
Any process that activates or increases the frequency, rate or extent of meiosis.
|
WNT5A,
SIRT2
|
GO:0045837
|
BP
|
negative regulation of membrane potential
|
Any process that stops, prevents, or reduces the frequency, rate or extent of establishment or extent of a membrane potential, the electric potential existing across any membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane.
|
IL6,
BNIP3
|