GO ID |
Ontology |
GO Term |
Term Definition |
Proteins |
GO:0045124
|
BP
|
regulation of bone resorption
|
Any process that modulates the frequency, rate or extent of bone tissue loss (resorption).
|
BGLAP,
ITGB3,
CSF1R,
S1PR1,
PDK4
|
GO:0045128
|
BP
|
negative regulation of reciprocal meiotic recombination
|
Any process that decreases the frequency, rate or extent of recombination during meiosis. Reciprocal meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate.
|
MSH2
|
GO:0045132
|
BP
|
meiotic chromosome segregation
|
The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets during M phase of the meiotic cell cycle.
|
SMC2,
SGOL1,
WAPL,
SMC4
|
GO:0045136
|
BP
|
development of secondary sexual characteristics
|
The process whose specific outcome is the progression of the secondary sexual characteristics over time, from their formation to the mature structures. In humans, these include growth of axillary, chest, and pubic hair, voice changes, testicular/penile enlargement, breast development and menstrual periods. Development occurs in response to sex hormone secretion.
|
B4GALT1,
BAX
|
GO:0045141
|
BP
|
meiotic telomere clustering
|
The cell cycle process in which the dynamic reorganization of telomeres occurs in early meiotic prophase, during which meiotic chromosome ends are gathered in a bouquet arrangement at the inner surface of the nuclear envelope proximal to the spindle pole body. This plays an important role in progression through meiosis and precedes synapsis.
|
MLH1,
TERF1,
UBE2B
|
GO:0045143
|
BP
|
homologous chromosome segregation
|
The cell cycle process in which replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the first division of the meiotic cell cycle. Each replicated chromosome, composed of two sister chromatids, aligns at the cell equator, paired with its homologous partner; this pairing off, referred to as synapsis, permits genetic recombination. One homolog (both sister chromatids) of each morphologic type goes into each of the resulting chromosome sets.
|
PTTG1,
PLK1,
ESPL1
|
GO:0045162
|
BP
|
clustering of voltage-gated sodium channels
|
The process in which voltage-gated sodium channels become localized together in high densities. In animals, nodes of Ranvier differ dramatically from internodal axonal regions in very high densities of voltage-dependent sodium (Nav) channels responsible for the rapid, inward ionic currents that produce membrane depolarization.
|
GLDN,
NRCAM,
SPTBN4
|
GO:0045163
|
BP
|
clustering of voltage-gated potassium channels
|
The process in which voltage-gated potassium channels become localized together in high densities. In animals, voltage-gated potassium (Kv) channels are clustered beneath the myelin sheath in regions immediately adjacent to paranodes, called juxtaparanodes, and along the inner mesaxon within the internode.
|
KCNIP2
|
GO:0045165
|
BP
|
cell fate commitment
|
The commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field.
|
SOX12,
SPRY2,
WNT2,
BMP2,
TAL1,
GAP43,
FGFR2,
PPARG,
WNT5A,
GATA4,
GAS1,
WNT3,
SOX8,
ERBB4,
SMAD2,
GATA6,
WNT2B,
WNT5B,
TRPS1,
WNT6
|
GO:0045176
|
BP
|
apical protein localization
|
Any process in which a protein is transported to, or maintained in, apical regions of the cell.
|
ARF4,
MAL,
RDX,
SHROOM2,
DLG5,
SHROOM3,
GOPC
|
GO:0045184
|
BP
|
establishment of protein localization
|
The directed movement of a protein to a specific location.
|
CHMP2A,
RAP2A,
ITGA2,
FLNA,
RDX,
LIMS1,
PLK1,
IST1,
VCP,
DLG4,
MDM2,
ANK3,
KPNB1,
KIF14,
CEP55,
PHLDB2,
NLGN1,
WBP2,
VIMP,
SMYD3,
CRIPT,
CORO1C
|
GO:0045186
|
BP
|
zonula adherens assembly
|
Assembly of the zonula adherens, a cell-cell adherens junction which forms a continuous belt near the apex of epithelial cells.
|
DLG5
|
GO:0045187
|
BP
|
regulation of circadian sleep/wake cycle, sleep
|
Any process that modulates the frequency, rate or extent of sleep; a readily reversible state of reduced awareness and metabolic activity that occurs periodically in many animals.
|
PTGDS
|
GO:0045188
|
BP
|
regulation of circadian sleep/wake cycle, non-REM sleep
|
Any process that modulates the frequency, rate or extent of non-rapid eye movement sleep.
|
IL6
|
GO:0045190
|
BP
|
isotype switching
|
The switching of activated B cells from IgM biosynthesis to biosynthesis of other isotypes of immunoglobulin, accomplished through a recombination process involving an intrachromosomal deletion involving switch regions that reside 5' of each constant region gene segment in the immunoglobulin heavy chain locus.
|
NBN,
RNF8,
ERCC1,
CD40LG,
MLH1,
MSH2,
MSH6,
EXOSC6,
EXOSC3,
EXO1
|
GO:0045191
|
BP
|
regulation of isotype switching
|
Any process that modulates the frequency, rate or extent of isotype switching.
|
IL10,
SUPT6H
|
GO:0045197
|
BP
|
establishment or maintenance of epithelial cell apical/basal polarity
|
Any cellular process that results in the specification, formation or maintenance of the apicobasal polarity of an epithelial cell.
|
ARF4,
PRKCI,
DLG4,
DLG1,
ILK,
DLG5
|
GO:0045198
|
BP
|
establishment of epithelial cell apical/basal polarity
|
The specification and formation of the apicobasal polarity of an epithelial cell.
|
WNT5A,
TCF15,
PTK7
|
GO:0045199
|
BP
|
maintenance of epithelial cell apical/basal polarity
|
The maintenance of the apicobasal polarity of an epithelial cell.
|
WDR1,
LHX2,
PDZD11,
LIN7B,
LIN7C
|
GO:0045200
|
BP
|
establishment of neuroblast polarity
|
The specification and formation of the apicobasal polarity of a neuroblast cell, a progenitor of the central nervous system.
|
FGF13,
DOCK7
|
GO:0045204
|
BP
|
MAPK export from nucleus
|
The directed movement of a MAP kinase from the nucleus to the cytoplasm.
|
DUSP16
|
GO:0045209
|
BP
|
MAPK phosphatase export from nucleus, leptomycin B sensitive
|
Leptomycin B-sensitive movement of a MAPK phosphatase from the nucleus to the cytoplasm.
|
DUSP16
|
GO:0045210
|
BP
|
FasL biosynthetic process
|
The chemical reactions and pathways resulting in the formation of fas ligand (FasL or CD95L), an antigen originally found to be expressed on the cell surface of activated human T-lymphocytes and B-lymphocytes and a variety of malignant human lymphoid cell lines.
|
PHLDA1
|
GO:0045213
|
BP
|
neurotransmitter receptor metabolic process
|
The chemical reactions and pathways involving neurotransmitter receptors.
|
NRG1
|
GO:0045214
|
BP
|
sarcomere organization
|
The myofibril assembly process that results in the organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs.
|
WDR1,
LDB3,
BMP10,
ITGB1,
KRT8,
KRT19,
TPM1,
PRKAR1A,
CAPN3,
ACTN2,
ACTG1,
ANKRD1,
TTN
|
GO:0045216
|
BP
|
cell-cell junction organization
|
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cell-cell junction. A cell-cell junction is a specialized region of connection between two cells.
|
CLDN1,
TGFB1,
NF2,
PRKCI,
TGFB2,
RAC1,
CXADR,
SMAD3,
OCLN,
NLGN4X,
MARVELD3,
CCM2
|
GO:0045217
|
BP
|
cell-cell junction maintenance
|
The maintenance of junctions between cells.
|
CSF1R,
PARD6A
|
GO:0045218
|
BP
|
zonula adherens maintenance
|
Maintaining the zonula adherens junction, the cell-cell adherens junction formed near the apex of epithelial cells.
|
CAMSAP3
|
GO:0045221
|
BP
|
negative regulation of FasL biosynthetic process
|
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of FasL.
|
JAK3
|
GO:0045225
|
BP
|
negative regulation of CD4 biosynthetic process
|
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of CD4.
|
ACOT8
|
GO:0045226
|
BP
|
extracellular polysaccharide biosynthetic process
|
The chemical reactions and pathways resulting in the formation of polysaccharides used in extracellular structures.
|
HAS2
|
GO:0045292
|
BP
|
mRNA cis splicing, via spliceosome
|
The joining together, after removal of an intervening sequence composed of one or more introns, of two segments of the same RNA molecule via spliceosomal catalysis to produce an mRNA composed only of exon sequences that all came from the same primary transcript.
|
NCBP1,
RBM22
|
GO:0045321
|
BP
|
leukocyte activation
|
A change in morphology and behavior of a leukocyte resulting from exposure to a specific antigen, mitogen, cytokine, cellular ligand, or soluble factor.
|
EDN1,
TOLLIP
|
GO:0045324
|
BP
|
late endosome to vacuole transport
|
The directed movement of substances from late endosomes to the vacuole. In yeast, after transport to the prevacuolar compartment, endocytic content is delivered to the late endosome and on to the vacuole. This pathway is analogous to endosome to lysosome transport.
|
PIK3R4
|
GO:0045329
|
BP
|
carnitine biosynthetic process
|
The chemical reactions and pathways resulting in the formation of carnitine (hydroxy-trimethyl aminobutyric acid), a compound that participates in the transfer of acyl groups across the inner mitochondrial membrane.
|
SHMT1,
ALDH9A1
|
GO:0045332
|
BP
|
phospholipid translocation
|
The movement of a phospholipid molecule from one leaflet of a membrane bilayer to the opposite leaflet.
|
ATP8B1,
ATP9A,
ABCA1,
ATP8B4,
TMEM30A,
ATP11B
|
GO:0045333
|
BP
|
cellular respiration
|
The enzymatic release of energy from inorganic and organic compounds (especially carbohydrates and fats) which either requires oxygen (aerobic respiration) or does not (anaerobic respiration).
|
NDUFS4,
NDUFS1,
CYCS,
NFATC4,
NDUFAF2,
NR4A3,
TBRG4,
PPARGC1A,
SLC25A13
|
GO:0045337
|
BP
|
farnesyl diphosphate biosynthetic process
|
The chemical reactions and pathways resulting in the formation of farnesyl diphosphate.
|
FDPS
|
GO:0045338
|
BP
|
farnesyl diphosphate metabolic process
|
The chemical reactions and pathways involving farnesyl diphosphate, an intermediate in carotenoid, sesquiterpene, squalene and sterol biosynthesis, as well as a substrate in protein farnesylation.
|
FDFT1
|
GO:0045342
|
BP
|
MHC class II biosynthetic process
|
The chemical reactions and pathways resulting in the formation of major histocompatibility protein class II.
|
SLC11A1
|
GO:0045345
|
BP
|
positive regulation of MHC class I biosynthetic process
|
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of MHC class I.
|
NLRC5,
HSPH1
|
GO:0045347
|
BP
|
negative regulation of MHC class II biosynthetic process
|
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of MHC class II.
|
PF4,
IL10,
MARCH8,
HDAC2
|
GO:0045348
|
BP
|
positive regulation of MHC class II biosynthetic process
|
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of MHC class II.
|
TLR4,
XBP1,
IL10
|
GO:0045351
|
BP
|
type I interferon biosynthetic process
|
The chemical reactions and pathways resulting in the formation of any type I interferon. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.
|
IFNAR1
|
GO:0045355
|
BP
|
negative regulation of interferon-alpha biosynthetic process
|
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interferon-alpha.
|
IL10,
NMI
|
GO:0045356
|
BP
|
positive regulation of interferon-alpha biosynthetic process
|
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interferon-alpha.
|
TLR3
|
GO:0045358
|
BP
|
negative regulation of interferon-beta biosynthetic process
|
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interferon-beta.
|
NMI
|
GO:0045359
|
BP
|
positive regulation of interferon-beta biosynthetic process
|
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interferon-beta.
|
TLR4,
TLR3,
TBK1
|
GO:0045401
|
BP
|
positive regulation of interleukin-3 biosynthetic process
|
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-3.
|
SYK
|
GO:0045408
|
BP
|
regulation of interleukin-6 biosynthetic process
|
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-6.
|
CEBPB
|
GO:0045409
|
BP
|
negative regulation of interleukin-6 biosynthetic process
|
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-6.
|
INPP5D,
GHSR,
GHRL
|
GO:0045410
|
BP
|
positive regulation of interleukin-6 biosynthetic process
|
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-6.
|
EREG,
IL1B,
PTAFR,
TIRAP,
TLR1
|
GO:0045415
|
BP
|
negative regulation of interleukin-8 biosynthetic process
|
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-8.
|
KLF4,
BCL3,
MAP2K5
|
GO:0045416
|
BP
|
positive regulation of interleukin-8 biosynthetic process
|
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-8.
|
TLR4,
BCL10,
TNF,
APOA2
|
GO:0045425
|
BP
|
positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process
|
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of granulocyte macrophage colony-stimulating factor.
|
SYK
|
GO:0045429
|
BP
|
positive regulation of nitric oxide biosynthetic process
|
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nitric oxide.
|
TLR4,
KLF4,
TLR5,
JAK2,
DDAH1,
DDAH2,
EGFR,
ASS1,
AGT,
INS,
TNF,
IL1B,
ITGB2,
IL6,
EDN1,
ICAM1,
INSR,
HSP90AA1,
HSP90AB1,
CLU,
PTX3,
AKT1,
PTGS2,
AGTR2,
HBB,
SMAD3,
PKD2,
TRPV1,
P2RX4,
KLF2
|
GO:0045444
|
BP
|
fat cell differentiation
|
The process in which a relatively unspecialized cell acquires specialized features of an adipocyte, an animal connective tissue cell specialized for the synthesis and storage of fat.
|
TMEM120B,
SOCS1,
KLF4,
SMAD6,
GPX1,
INHBB,
EGR2,
IL11,
NR4A1,
PSMB8,
AKT2,
GRK5,
SREBF1,
NR4A2,
ID4,
CEBPD,
GSK3B,
HMGA2,
SOX8,
RNASEL,
EP300,
FOXO1,
ARID5B,
STEAP4,
NIPBL,
BBS7,
LRRC8C,
NR4A3,
SDF4,
OSBPL11,
BBS2,
C1QTNF3,
TMEM120A,
OSBPL8,
WNT5B,
RETN,
MKKS,
PLCB1,
TCF7L2,
ERAP1,
FBXO9
|
GO:0045445
|
BP
|
myoblast differentiation
|
The process in which a relatively unspecialized cell acquires specialized features of a myoblast. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into striated muscle fibers.
|
HMGCR,
IGF1,
RB1,
LGALS1,
DTYMK,
JAG1,
MBNL1
|
GO:0045446
|
BP
|
endothelial cell differentiation
|
The process in which a mesodermal, bone marrow or neural crest cell acquires specialized features of an endothelial cell, a thin flattened cell. A layer of such cells lines the inside surfaces of body cavities, blood vessels, and lymph vessels, making up the endothelium.
|
EDF1,
HOXB5,
S1PR1,
JAG1,
SCUBE1,
BMPER
|
GO:0045453
|
BP
|
bone resorption
|
The process in which specialized cells known as osteoclasts degrade the organic and inorganic portions of bone, and endocytose and transport the degradation products.
|
TPP1,
TNFSF11,
PTH,
ADRB2,
RAC2,
CTNNB1,
CTSK,
RAB7A,
RAC1,
ZNF675,
NOX4
|
GO:0045454
|
BP
|
cell redox homeostasis
|
Any process that maintains the redox environment of a cell or compartment within a cell.
|
KRIT1,
AIFM1,
GSR,
CYBB,
IL6,
GPX1,
P4HB,
DLD,
TXN,
PDIA4,
NCF2,
NOS3,
PRDX6,
PDIA3,
PRDX2,
DDIT3,
GLRX,
GCLC,
SLC11A1,
PRDX1,
PRDX4,
PDIA5,
NCF4,
PDIA6,
TXNRD1,
TXNDC11,
QSOX2,
ERO1B,
DNAJC10,
NHLRC2,
ERO1A,
TXNDC15,
TXN2,
VIMP,
ERP44,
TMX4,
SH3BGRL3,
GLRX2,
DNAJC16
|
GO:0045471
|
BP
|
response to ethanol
|
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethanol stimulus.
|
MSTN,
GOT2,
GNRH1,
PENK,
PTH,
RBP4,
BGLAP,
HMGCR,
NTRK1,
TYMS,
S100A8,
CYP2E1,
ICAM1,
FYN,
CDK1,
TH,
CA3,
CD14,
GSTP1,
SPARC,
G6PD,
CCL2,
EEF2,
ALAD,
SLC2A4,
NQO1,
VCAM1,
TRH,
CNR1,
EEF1B2,
TNC,
CD27,
MAOB,
ADH7,
STAT3,
LEP,
ADCYAP1R1,
STAR,
OXCT1,
PTEN,
RPL10A,
ACTC1,
ABAT,
HAMP,
TJP1,
GRIN2A,
EIF4EBP1,
CASP8,
ADIPOQ,
CDO1,
AACS,
SETD7,
GGH,
BAD,
SDF4,
PEMT
|
GO:0045472
|
BP
|
response to ether
|
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ether stimulus.
|
TH,
MDM2
|
GO:0045475
|
BP
|
locomotor rhythm
|
The rhythm of the locomotor activity of an organism during its 24 hour activity cycle.
|
USP2,
NAGLU,
PTEN,
ID2,
MTA1,
NCOA2
|
GO:0045494
|
BP
|
photoreceptor cell maintenance
|
Any process preventing the degeneration of the photoreceptor, a specialized cell type that is sensitive to light.
|
MAK,
CROCC,
DRAM2,
BBS12,
NPHP3,
BBS1,
BBS10,
GPR98,
BBS2,
MKKS,
SPATA7
|
GO:0045540
|
BP
|
regulation of cholesterol biosynthetic process
|
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cholesterol.
|
SEC14L2,
APOB,
DHCR7
|
GO:0045541
|
BP
|
negative regulation of cholesterol biosynthetic process
|
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cholesterol.
|
ERLIN2,
APOE
|
GO:0045542
|
BP
|
positive regulation of cholesterol biosynthetic process
|
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cholesterol.
|
SREBF1
|
GO:0045556
|
BP
|
positive regulation of TRAIL biosynthetic process
|
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of TRAIL, TNF-related apoptosis inducing ligand.
|
TNFRSF8
|
GO:0045576
|
BP
|
mast cell activation
|
The change in morphology and behavior of a mast cell resulting from exposure to a cytokine, chemokine, soluble factor, or to (at least in mammals) an antigen which the mast cell has specifically bound via IgE bound to Fc-epsilonRI receptors.
|
NDRG1
|
GO:0045577
|
BP
|
regulation of B cell differentiation
|
Any process that modulates the frequency, rate or extent of B cell differentiation.
|
ZFP36L2,
ZFP36L1
|
GO:0045578
|
BP
|
negative regulation of B cell differentiation
|
Any process that stops, prevents, or reduces the frequency, rate or extent of B cell differentiation.
|
INHA,
INHBA,
ID2,
SFRP1
|
GO:0045579
|
BP
|
positive regulation of B cell differentiation
|
Any process that activates or increases the frequency, rate or extent of B cell differentiation.
|
XBP1,
CD27,
SYK,
MMP14,
STAT5B,
INPP5D,
BAD
|
GO:0045580
|
BP
|
regulation of T cell differentiation
|
Any process that modulates the frequency, rate or extent of T cell differentiation.
|
SLC46A2,
CYP26B1,
PRELID1
|
GO:0045581
|
BP
|
negative regulation of T cell differentiation
|
Any process that stops, prevents, or reduces the frequency, rate or extent of T cell differentiation.
|
CD74
|
GO:0045582
|
BP
|
positive regulation of T cell differentiation
|
Any process that activates or increases the frequency, rate or extent of T cell differentiation.
|
CD74,
RAG1,
XBP1,
IL12A,
BAD
|
GO:0045586
|
BP
|
regulation of gamma-delta T cell differentiation
|
Any process that modulates the frequency, rate or extent of gamma-delta T cell differentiation.
|
EGR3
|
GO:0045588
|
BP
|
positive regulation of gamma-delta T cell differentiation
|
Any process that activates or increases the frequency, rate or extent of gamma-delta T cell differentiation.
|
SYK,
STAT5B
|
GO:0045589
|
BP
|
regulation of regulatory T cell differentiation
|
Any process that modulates the frequency, rate or extent of differentiation of regulatory T cells.
|
CD28,
FANCD2
|
GO:0045590
|
BP
|
negative regulation of regulatory T cell differentiation
|
Any process that stops, prevents, or reduces the rate of differentiation of regulatory T cells.
|
IRF1,
TNFSF4
|
GO:0045591
|
BP
|
positive regulation of regulatory T cell differentiation
|
Any process that activates or increases the frequency, rate or extent of differentiation of regulatory T cells.
|
TGFB1,
CD46,
HLA-G
|
GO:0045595
|
BP
|
regulation of cell differentiation
|
Any process that modulates the frequency, rate or extent of cell differentiation, the process in which relatively unspecialized cells acquire specialized structural and functional features.
|
KLF4,
SPRY2,
FADS1,
PTBP3,
RAF1,
FGFR1,
APC,
PPP2R1A,
SIK1,
RUNX3,
RUNX2,
SPOCK2,
PLEKHB2,
PLEKHB1,
TCFL5,
EID1
|
GO:0045596
|
BP
|
negative regulation of cell differentiation
|
Any process that stops, prevents, or reduces the frequency, rate or extent of cell differentiation.
|
HMGB3,
TBX1,
GDF11,
KRAS,
TGFB1,
ITGB1,
IAPP,
SKIL,
MAPK1,
NR0B1,
CDK6,
SUZ12,
ANP32B,
HOPX,
ELF5
|
GO:0045597
|
BP
|
positive regulation of cell differentiation
|
Any process that activates or increases the frequency, rate or extent of cell differentiation.
|
SOCS3,
PAX4,
JAK2,
INS,
JUN,
AR,
JUNB,
JUND,
CTGF,
BTC,
NF2,
INSM1,
ZNF268,
RPS6KA1,
PPP1R13L,
SOX17,
PA2G4
|
GO:0045598
|
BP
|
regulation of fat cell differentiation
|
Any process that modulates the frequency, rate or extent of adipocyte differentiation.
|
NR1D1,
HES1,
MEX3C,
LGALS12,
HDAC6
|
GO:0045599
|
BP
|
negative regulation of fat cell differentiation
|
Any process that stops, prevents, or reduces the frequency, rate or extent of adipocyte differentiation.
|
ARNTL,
AXIN1,
INSIG1,
TGFB1,
TNF,
IL6,
ENPP1,
MMP11,
RORA,
DDIT3,
WNT5A,
ID4,
ZFP36L2,
JAG1,
SMAD3,
E2F1,
FOXO1,
CCDC85B,
ADIPOQ,
BBS12,
SIRT2,
ZFPM2,
JDP2,
TRIB2,
TRIB3,
GPER1
|
GO:0045600
|
BP
|
positive regulation of fat cell differentiation
|
Any process that activates or increases the frequency, rate or extent of adipocyte differentiation.
|
SH3PXD2B,
SNAI2,
CREBL2,
LRP5,
BMP2,
CREB1,
CEBPB,
XBP1,
ZFP36,
HTR2C,
AKT1,
PPARG,
ID2,
PPARD,
ZBTB16,
ZFP36L1,
STK4,
ADIRF,
ASXL2,
CARM1,
SFRP1,
TRPM4,
RARRES2,
CCDC3,
WNT5B,
NOCT,
WIF1
|
GO:0045601
|
BP
|
regulation of endothelial cell differentiation
|
Any process that modulates the frequency, rate or extent of endothelial cell differentiation.
|
APOLD1
|
GO:0045602
|
BP
|
negative regulation of endothelial cell differentiation
|
Any process that stops, prevents, or reduces the frequency, rate or extent of endothelial cell differentiation.
|
ID1,
XDH
|
GO:0045603
|
BP
|
positive regulation of endothelial cell differentiation
|
Any process that activates or increases the frequency, rate or extent of endothelial cell differentiation.
|
BMP4,
BMP6,
CTNNB1,
NOTCH1,
BTG1,
ATOH8
|
GO:0045604
|
BP
|
regulation of epidermal cell differentiation
|
Any process that modulates the frequency, rate or extent of epidermal cell differentiation.
|
MAFG,
MAFF
|
GO:0045605
|
BP
|
negative regulation of epidermal cell differentiation
|
Any process that stops, prevents, or reduces the frequency, rate or extent of epidermal cell differentiation.
|
EZH2
|
GO:0045606
|
BP
|
positive regulation of epidermal cell differentiation
|
Any process that activates or increases the frequency, rate or extent of epidermal cell differentiation.
|
BMP4,
SFN,
PTCH1,
SFRP4
|
GO:0045607
|
BP
|
regulation of auditory receptor cell differentiation
|
Any process that modulates the frequency, rate or extent of auditory hair cell differentiation.
|
MYCN
|
GO:0045608
|
BP
|
negative regulation of auditory receptor cell differentiation
|
Any process that stops, prevents, or reduces the frequency, rate or extent of auditory hair cell differentiation.
|
NOTCH1,
HES1
|
GO:0045616
|
BP
|
regulation of keratinocyte differentiation
|
Any process that modulates the frequency, rate or extent of keratinocyte differentiation.
|
ROCK2,
ZFP36,
ZFP36L1,
AQP3,
ERRFI1
|
GO:0045617
|
BP
|
negative regulation of keratinocyte differentiation
|
Any process that stops, prevents, or reduces the frequency, rate or extent of keratinocyte differentiation.
|
SRSF6
|
GO:0045618
|
BP
|
positive regulation of keratinocyte differentiation
|
Any process that activates or increases the frequency, rate or extent of keratinocyte differentiation.
|
CYP27B1,
H2AFY,
VDR,
NME2,
NOTCH1,
H2AFY2,
NCOA3
|
GO:0045619
|
BP
|
regulation of lymphocyte differentiation
|
Any process that modulates the frequency, rate or extent of lymphocyte differentiation.
|
FAS,
NDFIP1
|
GO:0045624
|
BP
|
positive regulation of T-helper cell differentiation
|
Any process that activates or increases the frequency, rate or extent of T-helper cell differentiation.
|
SHB
|