GO:0036518

BP

chemorepulsion of dopaminergic neuron axon

The process in which a dopaminergic neuron growth cone is directed to a specific target site in response to a repulsive chemical cue.

WNT5A

GO:0038001

BP

paracrine signaling

The transfer of information from one cell to another, where the signal travels from the signal-producing cell to the receiving cell by passive diffusion or bulk flow in intercellular fluid. The signaling cell and the receiving cell are usually in the vicinity of each other.

TNFSF11, PDGFB, SERPINB3

GO:0038002

BP

endocrine signaling

The transfer of information from one cell to another, where an endocrine hormone is transported from the signal-producing cell to the receiving cell via the circulatory system (via blood, lymph or cerebrospinal fluid). The signaling cell and the receiving cell are often distant to each other.

KRAS

GO:0038003

BP

opioid receptor signaling pathway

The series of molecular signals generated as a consequence of an opioid receptor binding to one of its physiological ligands.

OPRL1, NPBWR1, SIGMAR1

GO:0038007

BP

netrin-activated signaling pathway

A series of molecular events initiated by the binding of a netrin protein to a receptor on the surface of the target cell, and ending with regulation of a downstream cellular process, e.g. transcription. Netrins can act as chemoattractant signals for some cells and chemorepellent signals for others. Netrins also have roles outside of cell and axon guidance.

UNC5C, PTK2

GO:0038016

BP

insulin receptor internalization

A receptor-mediated endocytosis process that results in the movement of an insulin receptor from the plasma membrane to the inside of the cell.

LMBRD1

GO:0038026

BP

reelin-mediated signaling pathway

A series of molecular signals initiated by the binding of reelin (a secreted glycoprotein) to a receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.

VLDLR

GO:0038027

BP

apolipoprotein A-I-mediated signaling pathway

A series of molecular signals initiated by the binding of apolipoprotein A-I to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.

ABCA1, ITGB3, ITGAV, RHOA

GO:0038028

BP

insulin receptor signaling pathway via phosphatidylinositol 3-kinase

The series of molecular signals generated as a consequence of the insulin receptor binding to its physiological ligand, where the signal is passed on via the phosphatidylinositol 3-kinase cascade.

IGF2, PIK3CA, C2CD5

GO:0038031

BP

non-canonical Wnt signaling pathway via JNK cascade

The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, where the signal is passed on via the JNK cascade.

FZD7, WNT5A

GO:0038033

BP

positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway

A series of molecular signals initiated by the binding of a vascular endothelial growth factor (VEGF) to a VEGFR on the surface of a cell, which activates or increases the frequency, rate or extent of endothelial cell chemotaxis.

HSPB1, VEGFA, PRKD1, PRKD2

GO:0038043

BP

interleukin-5-mediated signaling pathway

A series of molecular signals initiated by the binding of interleukin-5 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.

IL5RA

GO:0038061

BP

NIK/NF-kappaB signaling

The process in which a signal is passed on to downstream components within the cell through the NIK-dependent processing and activation of NF-KappaB. Begins with activation of the NF-KappaB-inducing kinase (NIK), which in turn phosphorylates and activates IkappaB kinase alpha (IKKalpha). IKKalpha phosphorylates the NF-Kappa B2 protein (p100) leading to p100 processing and release of an active NF-KappaB (p52).

PSMD11, PSMD12, PSMD3, PSMD10, UBC, PSMC3, NFKB1, PSMB1, PSMA1, PSMA2, PSMA3, PSMA4, PSMB8, PSMB9, PSMB4, PSMB5, PSMC2, PSMB10, PSMC4, PSMB3, PSMD7, PPP4C, UBE2M, PSME3, PSMC1, PSMC6, RPS27A, UBA52, SKP1, RELB, REL, PSMD2, BIRC3, PSME4, BTRC

GO:0038063

BP

collagen-activated tyrosine kinase receptor signaling pathway

A series of molecular signals initiated by the binding of collagen to a receptor on the surface of the target cell where the receptor possesses tyrosine kinase activity. The pathway ends with regulation of a downstream cellular process, e.g. transcription.

DDR1

GO:0038065

BP

collagen-activated signaling pathway

A series of molecular signals initiated by collagen binding to a cell surface receptor, and ending with regulation of a downstream cellular process, e.g. transcription.

ITGA2, ITGA11

GO:0038066

BP

p38MAPK cascade

An intracellular protein kinase cascade containing at least a p38 MAPK, a MAPKK and a MAP3K. The cascade can also contain two additional tiers: the upstream MAP4K and the downstream MAP Kinase-activated kinase (MAPKAPK). The kinases in each tier phosphorylate and activate the kinases in the downstream tier to transmit a signal within a cell.

ZFP36, MAPKAPK2, ZFP36L1, MAPK14, MAP3K5

GO:0038083

BP

peptidyl-tyrosine autophosphorylation

The phosphorylation by a protein of one or more of its own tyrosine amino acid residues, or a tyrosine residue on an identical protein.

JAK2, INSR, FYN, LYN, IGF1R, FGR, JAK1, MAPK3, CSK, ABL2, SYK, JAK3, PTK2, TNK2, DDR1, ERBB4, STYK1

GO:0038084

BP

vascular endothelial growth factor signaling pathway

A series of molecular signals initiated by the binding of a vascular endothelial growth factor (VEGF) to a receptor on the surface of the target cell, and ending with regulation of a downstream cellular process, e.g. transcription.

NRP2, FLT4, FOXC1

GO:0038089

BP

positive regulation of cell migration by vascular endothelial growth factor signaling pathway

A series of molecular signals initiated by the binding of a vascular endothelial growth factor (VEGF) to a receptor on the surface of a cell, which activates or increases the frequency, rate or extent of the orderly movement of a cell from one site to another.

MYO1C

GO:0038091

BP

positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway

A series of molecular signals initiated by the binding of a vascular endothelial growth factor (VEGF) to a platelet-derived growth factor receptor (PDGFR) on the surface of a cell, which activates or increases the frequency, rate or extent of cell proliferation.

PDGFRB, VEGFA, PDGFRA

GO:0038092

BP

nodal signaling pathway

A series of molecular signals initiated by the binding of a nodal protein to an activin receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.

ACVR1B, SMAD3, SMAD2

GO:0038093

BP

Fc receptor signaling pathway

A series of molecular signals initiated by the binding of the Fc portion of an immunoglobulin to an Fc receptor on the surface of a signal-receiving cell, and ending with regulation of a downstream cellular process, e.g. transcription. The Fc portion of an immunoglobulin is its C-terminal constant region.

KIT, FCGR1B

GO:0038094

BP

Fc-gamma receptor signaling pathway

A series of molecular signals initiated by the binding of the Fc portion of immunoglobulin G (IgG) to an Fc-gamma receptor on the surface of a signal-receiving cell, and ending with regulation of a downstream cellular process, e.g. transcription. The Fc portion of an immunoglobulin is its C-terminal constant region.

CLEC4D

GO:0038095

BP

Fc-epsilon receptor signaling pathway

A series of molecular signals initiated by the binding of the Fc portion of immunoglobulin E (IgE) to an Fc-epsilon receptor on the surface of a signal-receiving cell, and ending with regulation of a downstream cellular process, e.g. transcription. The Fc portion of an immunoglobulin is its C-terminal constant region.

PSMD11, PSMD12, MAP2K7, PSMD3, MAP3K7, PSMD10, NFATC1, BCL10, FOS, NRAS, KRAS, JUN, LYN, UBC, VAV1, PLCG2, PSMC3, NFKB1, PSMB1, PSMA1, PSMA2, PSMA3, PSMA4, MAPK3, PIK3R1, PSMB8, PSMB9, PSMB4, PSMB5, MAPK1, PSMC2, PSMB10, PIK3CA, PIK3CB, SYK, PSMC4, MAPK8, MAPK9, PSMB3, PSMD7, PSME3, CALM2, PSMC1, PSMC6, RPS27A, UBA52, GRB2, RAC1, SKP1, RELA, PRKCQ, SOS1, PPP3CA, PAK2, PSMD2, UBE2V1, NFATC2, PSME4, TAB1, TAB3, VAV3, BTRC

GO:0038096

BP

Fc-gamma receptor signaling pathway involved in phagocytosis

An Fc-gamma receptor signaling pathway that contributes to the endocytic engulfment of external particulate material by phagocytes.

WIPF3, MYO1G, MYO1C, WASL, ARPC2, ARPC3, FYN, HSP90AA1, LYN, HSP90AB1, FGR, FCGR1A, FCGR2A, VAV1, PLCG2, MAPK3, PIK3R1, MAPK1, PIK3CA, PIK3CB, SYK, ARPC4, ACTB, CDC42, ACTR3, ACTR2, GRB2, RAC1, ACTG1, PTK2, PRKCD, CYFIP1, ABI1, ELMO1, CYFIP2, MYO10, VAV3, MYH2, WASF2

GO:0038097

BP

positive regulation of mast cell activation by Fc-epsilon receptor signaling pathway

An Fc-epsilon receptor signaling pathway that results in the change in morphology and behavior of a mast cell resulting from exposure to a cytokine, chemokine, soluble factor, or to (at least in mammals) an antigen which the mast cell has specifically bound via IgE bound to Fc-epsilonRI receptors.

NR4A3

GO:0038098

BP

sequestering of BMP from receptor via BMP binding

Binding to a bone morphogenetic protein (BMP) in the extracellular region, and inhibiting BMP signaling by preventing BMP from binding to its cell surface receptor.

NBL1, GREM2

GO:0038108

BP

negative regulation of appetite by leptin-mediated signaling pathway

A series of molecular signals initiated by the binding of leptin to a receptor on the surface of a cell, which reduces appetite, the desire or physical craving for food.

LEP, BBS2, MKKS

GO:0038109

BP

Kit signaling pathway

A series of molecular signals that starts with the binding of stem cell factor to the tyrosine kinase receptor KIT on the surface of a cell, and ends with regulation of a downstream cellular process, e.g. transcription. Stem cell factor (KIT ligand) binding to the receptor Kit mediates receptor dimerization, activation of its intrinsic tyrosine kinase activity and autophosphorylation. The activated receptor then phosphorylates various substrates, thereby activating distinct signaling cascades within the cell that trigger a change in state or activity of the cell.

KIT

GO:0038110

BP

interleukin-2-mediated signaling pathway

A series of molecular signals initiated by the binding of interleukin-2 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.

JAK1

GO:0038111

BP

interleukin-7-mediated signaling pathway

A series of molecular signals initiated by the binding of interleukin-7 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.

IL7R

GO:0038112

BP

interleukin-8-mediated signaling pathway

A series of molecular signals initiated by the binding of interleukin-8 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.

CXCR2

GO:0038113

BP

interleukin-9-mediated signaling pathway

A series of molecular signals initiated by the binding of interleukin-9 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.

IL9R

GO:0038123

BP

toll-like receptor TLR1:TLR2 signaling pathway

A series of molecular signals initiated by the binding of a heterodimeric TLR1:TLR2 complex to one of it's physiological ligands, followed by transmission of the signal by the activated receptor, and ending with regulation of a downstream cellular process, e.g. transcription.

TLR2, CD14, TLR1

GO:0038124

BP

toll-like receptor TLR6:TLR2 signaling pathway

A series of molecular signals initiated by the binding of a heterodimeric TLR6:TLR2 complex to one of it's physiological ligands, followed by transmission of the signal by the activated receptor, and ending with regulation of a downstream cellular process, e.g. transcription.

TLR2, CD14, CD36

GO:0038127

BP

ERBB signaling pathway

A series of molecular signals initiated by binding of a ligand to a member of the ERBB family of receptor tyrosine kinases on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.

MAPK1, NRG1, PTPN11

GO:0038128

BP

ERBB2 signaling pathway

A series of molecular signals initiated by binding of a ligand to a member of the ERBB family of receptors on the surface of a cell, where the signal is transmitted by ERBB2. The pathway ends with regulation of a downstream cellular process, e.g. transcription. ERBB2 receptors are themselves unable to bind to ligands, but act as a signal-amplifying tyrosine kinase within a heterodimeric pair.

EREG, EGFR, NRAS, KRAS, ERBB2, HSP90AA1, UBC, ERBB3, PIK3R1, AKT1, BTC, PIK3CA, RPS27A, UBA52, GRB2, NRG1, SOS1, GAB1, ERBB4, CDC37, CUL5, HBEGF, STUB1

GO:0038145

BP

macrophage colony-stimulating factor signaling pathway

A series of molecular signals initiated by the binding of the cytokine macrophage colony-stimulating factor (M-CSF) to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.

CSF1R

GO:0038154

BP

interleukin-11-mediated signaling pathway

A series of molecular signals initiated by the binding of interleukin-11 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.

IL6ST

GO:0038155

BP

interleukin-23-mediated signaling pathway

A series of molecular signals initiated by the binding of interleukin-23 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.

IL12RB1

GO:0038161

BP

prolactin signaling pathway

A series of molecular signals initiated by the binding of the peptide hormone prolactin to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.

PRLR, STAT5A, STAT5B

GO:0038162

BP

erythropoietin-mediated signaling pathway

A series of molecular signals initiated by the binding of erythropoietin (EPO) to the erythropoietin receptor (EPO-R) on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.

KIT, EPOR

GO:0038163

BP

thrombopoietin-mediated signaling pathway

A series of molecular signals initiated by the binding of a thrombopoietin to the thrombopoietin receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.

CIB1

GO:0038165

BP

oncostatin-M-mediated signaling pathway

A series of molecular signals initiated by the binding of oncostatin-M (OSM) to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. OSM can signal via at least two different receptors (a specific receptor and a LIF receptor) to activate different downstream signal transduction pathways.

IL6ST, LIFR, OSMR

GO:0038166

BP

angiotensin-activated signaling pathway

The series of molecular signals generated as a consequence of angiotensin II binding to an angiotensin receptor on the surface of the cell, and proceeding with the activated receptor transmitting the signal to a heterotrimeric G-protein complex to initiate a change in cell activity. Ends with regulation of a downstream cellular process, e.g. transcription.

AHCYL1, CA2, AGTR1, AGTR2, AGTRAP

GO:0038170

BP

somatostatin signaling pathway

The series of molecular signals generated as a consequence of the peptide somatostatin (SST) binding to a somatostatin receptor (SSTR). The pathway proceeds with the receptor transmitting the signal to a heterotrimeric G-protein complex and ends with regulation of a downstream cellular process, e.g. transcription.

SSTR1, SSTR5

GO:0038171

BP

cannabinoid signaling pathway

The series of molecular signals generated as a consequence of a cannabinoid binding to a cell surface receptor. The pathway proceeds with the receptor transmitting the signal to a heterotrimeric G-protein complex and ends with regulation of a downstream cellular process, e.g. transcription. Cannabinoids are a class of diverse chemical compounds that include the endocannabinoids and the phytocannabinoids.

CNR1

GO:0038172

BP

interleukin-33-mediated signaling pathway

A series of molecular signals initiated by the binding of interleukin-33 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.

IL1RL1, IL1RAP

GO:0038178

BP

complement component C5a signaling pathway

A series of molecular signals generated as a consequence of a the C5a component of the complement pathway binding to a complement receptor, and ending with regulation of a downstream cellular process. C5a is a peptide derived from the C5 complement factor.

C5AR1

GO:0038179

BP

neurotrophin signaling pathway

A series of molecular signals initiated by the binding of a neurotrophin to a receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription. Neurotrophins are a family of secreted growth factors that induce the survival, development, and function of neurons.

NTRK2

GO:0038180

BP

nerve growth factor signaling pathway

A series of molecular signals initiated by the binding of nerve growth factor (NGF) to a receptor on the surface of the target cell, and ending with regulation of a downstream cellular process, e.g. transcription.

NTRK1, CORO1A, RAP1A, RAPGEF1, MAGI2, KIDINS220

GO:0038183

BP

bile acid signaling pathway

A series of molecular signals initiated by the binding of a bile acid to a receptor, and ending with regulation of a downstream cellular process, e.g. transcription.

VDR, NR1H4

GO:0038185

BP

intracellular bile acid receptor signaling pathway

A series of molecular signals initiated by a bile acid binding to an receptor located within a cell, and ending with regulation of a downstream cellular process, e.g. transcription.

NR1H4

GO:0038188

BP

cholecystokinin signaling pathway

The series of molecular signals generated as a consequence of cholecystokinin binding to a receptor on the surface of the cell, and proceeding with the activated receptor transmitting the signal to a heterotrimeric G-protein complex to initiate a change in cell activity. Ends with regulation of a downstream cellular process, e.g. transcription.

CCKBR

GO:0038190

BP

VEGF-activated neuropilin signaling pathway

A series of molecular signals initiated by the binding of vascular endothelial growth factor (VEGF) to a neuropilin protein on the surface of a target cell, followed by transmission of the signal, and ending with regulation of a downstream cellular process, e.g. transcription.

NRP1, VEGFA

GO:0038194

BP

thyroid-stimulating hormone signaling pathway

The series of molecular signals generated as a consequence of thyroid-stimulating hormone (thyrotropin) binding to a cell surface receptor. The pathway proceeds with the receptor transmitting the signal to a heterotrimeric G-protein complex and ends with regulation of a downstream cellular process, e.g. transcription.

PAX8

GO:0038195

BP

urokinase plasminogen activator signaling pathway

A series of molecular signals initiated by the binding of urokinase plasminogen activator to a receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.

PLAUR

GO:0038202

BP

TORC1 signaling

A series of intracellular molecular signals mediated by TORC1; TOR (target of rapamycin) in complex with at least Raptor (regulatory-associated protein of TOR), or orthologs of, and other signaling components.

NPRL3

GO:0038203

BP

TORC2 signaling

A series of intracellular molecular signals mediated by TORC2; TOR (rapamycin-insensitive companion of TOR) in complex with at least Rictor (regulatory-associated protein of TOR), or orthologs of, and other signaling components.

MAPKAP1, PINK1

GO:0039003

BP

pronephric field specification

The process in which regions of the embryo are delineated into the area in which the pronephric kidney will develop.

PAX8

GO:0039008

BP

pronephric nephron tubule morphogenesis

The process in which the anatomical structures of a pronephric nephron tubule are generated and organized from an epithelium. A pronephric nephron tubule is an epithelial tube that is part of the pronephric nephron.

AHI1

GO:0039023

BP

pronephric duct morphogenesis

The process in which the anatomical structures of the pronephric duct are generated and organized. The pronephric duct collects the filtrate from the pronephric tubules and opens to the exterior of the kidney.

AHI1

GO:0039520

BP

induction by virus of host autophagy

Any process in which a virus activates or increases the frequency, rate or extent of autophagy in the host.

EIF2AK4

GO:0039529

BP

RIG-I signaling pathway

Any series of molecular signals generated as a consequence of the cytoplasmic pattern recognition receptor (PRR) RIG-1 (also known as DDX58) binding to viral RNA. RIG-I detects RNA synthesized during active viral replication and triggers a signaling pathway to protect the host against viral infection, for example by inducing the expression of antiviral cytokines.

MAVS, LSM14A

GO:0039532

BP

negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway

Any process that stops, prevents, or reduces the frequency, rate or extent of the series of molecular signals generated as a consequence of a virus or viral RNA binding to a pattern recognition receptor (PRR) located in the cytoplasm.

TSPAN6

GO:0039534

BP

negative regulation of MDA-5 signaling pathway

Any process that stops, prevents, or reduces the frequency, rate or extent of the series of molecular signals generated as a consequence of the cytoplasmic pattern recognition receptor (PRR) MDA-5 (also known as IFIH1) binding to viral RNA.

C1QBP, TKFC

GO:0039535

BP

regulation of RIG-I signaling pathway

Any process that modulates the frequency, rate or extent of the series of molecular signals generated as a consequence of the cytoplasmic pattern recognition receptor (PRR) RIG-1 (also known as DDX58) binding to viral RNA.

BIRC3

GO:0039536

BP

negative regulation of RIG-I signaling pathway

Any process that stops, prevents, or reduces the frequency, rate or extent of the series of molecular signals generated as a consequence of the cytoplasmic pattern recognition receptor (PRR) RIG-1 (also known as DDX58) binding to viral RNA.

C1QBP, SEC14L1

GO:0039650

BP

suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process

Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host caspase activity. Caspases are cysteine-type endopeptidases which contribute to the apoptotic process.

CASP8

GO:0039689

BP

negative stranded viral RNA replication

A viral genome replication process where the template genome is negative stranded, single stranded RNA ((-)ssRNA).

ATG16L2

GO:0039692

BP

single stranded viral RNA replication via double stranded DNA intermediate

A viral genome replication where the template is single-stranded RNA (ssRNA), and which proceeds via a double stranded DNA (dsDNA) intermediate molecule. Viral genomic RNA is first reverse transcribed into dsDNA, which integrates into the host chromosomal DNA, where it is transcribed by host RNA polymerase II.

SUPT5H

GO:0039694

BP

viral RNA genome replication

The replication of a viral RNA genome.

RAB29, ROCK2, RAB5A, CDC42, EEA1, PCBP1

GO:0039702

BP

viral budding via host ESCRT complex

Viral budding which uses a host ESCRT protein complex, or complexes, to mediate the budding process.

VPS37C, CHMP2A, VPS4B, VPS37A, PDCD6IP, MVB12A, CHMP4B

GO:0040001

BP

establishment of mitotic spindle localization

The cell cycle process in which the directed movement of the mitotic spindle to a specific location in the cell occurs.

ESPL1, KPNB1, NUSAP1

GO:0040007

BP

growth

The increase in size or mass of an entire organism, a part of an organism or a cell.

FOXP2, CCNB2, GDF11, INHBA, INHBB, BMP2, BMP3, VEGFA, BMP6, BMP8B, GDF5, SEPP1, RFTN1, BMP8A, ST6GAL2

GO:0040008

BP

regulation of growth

Any process that modulates the frequency, rate or extent of the growth of all or part of an organism so that it occurs at its proper speed, either globally or in a specific part of the organism's development.

SOCS3, SOCS6, SOCS1, SOCS5, CREG1, CSPG5, YEATS4, ACTL6A, GAP43, TKT, PPP2R1A, HMGA2, AES, PAK2, GAS6, NEDD9, MORF4L2, IGSF11, BRMS1L, KCTD11, TSPYL5, ARMC10, UBE2E3, EPC1, ING3, MORF4L1, RUVBL2, RUVBL1

GO:0040011

BP

locomotion

Self-propelled movement of a cell or organism from one location to another.

ATP1A2

GO:0040012

BP

regulation of locomotion

Any process that modulates the frequency, rate or extent of locomotion of a cell or organism.

SNCA

GO:0040013

BP

negative regulation of locomotion

Any process that stops, prevents, or reduces the frequency, rate or extent of locomotion of a cell or organism.

GHRL

GO:0040014

BP

regulation of multicellular organism growth

Any process that modulates the frequency, rate or extent of growth of the body of an organism so that it reaches its usual body size.

PRL, IGF1, APP, GHR, FGFR2, NPY1R, STAT3, STAT5A, PIK3CA, GDF5, STAT5B, PTPN11, GPAT4, FTO, TNKS2, MBD5

GO:0040015

BP

negative regulation of multicellular organism growth

Any process that stops, prevents, or reduces the frequency, rate or extent of growth of an organism to reach its usual body size.

STC2, ADRB2, ADRB1, ADRB3, PTCH1, FXN, BBS2

GO:0040016

BP

embryonic cleavage

The first few specialized divisions of an activated animal egg.

TOP1, TOP2A, ERCC2, PIK3CB, CUL3, TPRA1, AATF

GO:0040017

BP

positive regulation of locomotion

Any process that activates or increases the frequency, rate or extent of locomotion of a cell or organism.

BVES

GO:0040018

BP

positive regulation of multicellular organism growth

Any process that activates or increases the frequency, rate or extent of growth of an organism to reach its usual body size.

GH1, GHRH, BCL2, GHR, DRD2, EZR, CREB1, PPIB, STAT5B, HSF1, PLS1, NIPBL, GHSR, BBS2, SPTBN4, GPAM, MKKS, CHD7, GHRL

GO:0040019

BP

positive regulation of embryonic development

Any process that activates or increases the frequency, rate or extent of embryonic development.

OTX2, AMOT, PLCB1

GO:0040020

BP

regulation of meiotic nuclear division

Any process that modulates the frequency, rate or extent of meiosis, the process in which the nucleus of a diploid cell divides twice forming four haploid cells, one or more of which usually function as gametes.

CALR, CDC20, PDE3A, FZR1

GO:0040023

BP

establishment of nucleus localization

The directed movement of the nucleus to a specific location within a cell.

PTK2

GO:0040029

BP

regulation of gene expression, epigenetic

Any process that modulates the frequency, rate or extent of gene expression; the process is mitotically or meiotically heritable, or is stably self-propagated in the cytoplasm of a resting cell, and does not entail a change in DNA sequence.

H2AFY, GPX1, HDAC4, MTA1, TDG, IFI16, GLMN, ZNF335, HDAC6, HDAC5, KLF2

GO:0040032

BP

post-embryonic body morphogenesis

The process in which the anatomical structures of the post-embryonic soma are generated and organized.

GNAS, GNAS

GO:0040036

BP

regulation of fibroblast growth factor receptor signaling pathway

Any process that modulates the frequency, rate or extent of fibroblast growth factor receptor signaling pathway activity.

FGFR2, OTX2, RUNX2, DUSP6, SULF1, FAM20C, HHIP

GO:0040037

BP

negative regulation of fibroblast growth factor receptor signaling pathway

Any process that stops, prevents, or reduces the frequency, rate or extent of fibroblast growth factor receptor signaling pathway activity.

SPRY2, SPRY1, THBS1, GPC1, WNT5A, SHISA2, SULF2, SULF1

GO:0040038

BP

polar body extrusion after meiotic divisions

The cell cycle process in which two small cells are generated, as byproducts destined to degenerate, as a result of the first and second meiotic divisions of a primary oocyte during its development to a mature ovum. One polar body is formed in the first division of meiosis and the other in the second division; at each division, the cytoplasm divides unequally, so that the polar body is of much smaller size than the developing oocyte. At the second division in which a polar body is formed, the polar body and the developing oocyte each contain a haploid set of chromosomes.

FMN2

GO:0042023

BP

DNA endoreduplication

Regulated re-replication of DNA within a single cell cycle, resulting in an increased cell ploidy. An example of this process occurs in the synthesis of Drosophila salivary gland cell polytene chromosomes.

ZPR1

GO:0042026

BP

protein refolding

The process carried out by a cell that restores the biological activity of an unfolded or misfolded protein, using helper proteins such as chaperones.

DNAJA2, HSP90AA1, HSPA1A, HSPA1B, HSPD1, HSPA6, DNAJB2, HSPA1L, B2M, DNAJA4

GO:0042033

BP

chemokine biosynthetic process

The chemical reactions and pathways resulting in the formation of chemokines, any member of a family of small chemotactic cytokines; their name is derived from their ability to induce directed chemotaxis in nearby responsive cells. All chemokines possess a number of conserved cysteine residues involved in intramolecular disulfide bond formation. Some chemokines are considered pro-inflammatory and can be induced during an immune response to recruit cells of the immune system to a site of infection, while others are considered homeostatic and are involved in controlling the migration of cells during normal processes of tissue maintenance or development. Chemokines are found in all vertebrates, some viruses and some bacteria.

IL18

GO:0042035

BP

regulation of cytokine biosynthetic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cytokines.

IGF2BP3, PRG2, ZNF287, IGF2BP2

GO:0042036

BP

negative regulation of cytokine biosynthetic process

Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cytokines.

TIA1, RNF128, FOXP3

GO:0042045

BP

epithelial fluid transport

The directed movement of fluid across epithelia.

AHCYL1, EDN1, ITPR1

GO:0042048

BP

olfactory behavior

The behavior of an organism in response to an odor.

UBR3, CHD7

GO:0042053

BP

regulation of dopamine metabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving dopamine.

PARK2, NR4A2, PNKD