GO ID |
Ontology |
GO Term |
Term Definition |
Proteins |
GO:0035607
|
BP
|
fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development
|
The series of molecular signals generated as a consequence of a fibroblast growth factor-type receptor binding to one of its physiological ligands, which contributes to the progression of the orbitofrontal cortex over time from its initial formation until its mature state.
|
FGFR1,
FGFR2
|
GO:0035609
|
BP
|
C-terminal protein deglutamylation
|
The removal of a C-terminal, gene-encoded glutamate residue from a protein.
|
AGBL1,
AGTPBP1
|
GO:0035610
|
BP
|
protein side chain deglutamylation
|
The removal of a glutamate residue from the side chain of a protein. Glutamate side chains are added to glutamic acid residues within the primary protein sequence during polyglutamylation.
|
AGBL1,
AGTPBP1
|
GO:0035616
|
BP
|
histone H2B conserved C-terminal lysine deubiquitination
|
A histone deubiquitination process in which a ubiquitin monomer is removed from a conserved lysine residue in the C-terminus of histone H2B. The conserved lysine residue is K119 in fission yeast, K123 in budding yeast, or K120 in mammals.
|
USP15
|
GO:0035622
|
BP
|
intrahepatic bile duct development
|
The progression of the intrahepatic bile ducts over time, from their formation to the mature structure. Intrahepatic bile ducts (bile ducts within the liver) collect bile from bile canaliculi in the liver, and connect to the extrahepatic bile ducts (bile ducts outside the liver).
|
SOX9
|
GO:0035623
|
BP
|
renal glucose absorption
|
A renal system process in which glucose is taken up from the collecting ducts and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures.
|
HNF1A
|
GO:0035624
|
BP
|
receptor transactivation
|
The process in which a receptor is activated by another receptor. Receptor transactivation can occur through different mechanisms and includes cross-talk between signaling pathways where one receptor activates a receptor for a different ligand, and also activation of subunits within a receptor oligomer.
|
NCOA3
|
GO:0035625
|
BP
|
epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway
|
The process in which an epidermal growth factor-activated receptor is activated via signaling events from a G-protein coupled receptor. This is an example of cross-talk between the EGF and GPCR signaling pathways.
|
ADRA2B,
ADAM17
|
GO:0035630
|
BP
|
bone mineralization involved in bone maturation
|
The deposition of hydroxyapatite, involved in the progression of the skeleton from its formation to its mature state.
|
IGF1,
BMP2,
LEP,
ANO6
|
GO:0035633
|
BP
|
maintenance of blood-brain barrier
|
Preserving the permeability barrier between the blood and the brain in a stable functional or structural state. The cells in the brain are packed tightly together preventing the passage of most molecules from the blood into the brain. Only lipid soluble molecules or those that are actively transported can pass through the blood-brain barrier.
|
PTGS2
|
GO:0035634
|
BP
|
response to stilbenoid
|
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of exposure to a stilbenoid. Stilbenoids are secondary products of heartwood formation in trees that can act as phytoalexins. Stilbenoids are hydroxylated derivatives of stilbene. They belong to the family of phenylpropanoids and share most of their biosynthesis pathway with chalcones.
|
CD36
|
GO:0035640
|
BP
|
exploration behavior
|
The specific behavior of an organism in response to a novel environment or stimulus.
|
CHL1,
ITGA3,
AGTR2,
ABAT
|
GO:0035641
|
BP
|
locomotory exploration behavior
|
The specific movement from place to place of an organism in response to a novel environment.
|
PENK,
DPP4,
DLG4,
LSAMP,
TNR
|
GO:0035644
|
BP
|
phosphoanandamide dephosphorylation
|
The process of removing one or more phosphate groups from a phosphorylated anandamide.
|
PTPN22
|
GO:0035646
|
BP
|
endosome to melanosome transport
|
The directed movement of substances from endosomes to the melanosome, a specialised lysosome-related organelle.
|
AP3D1,
RAB32,
BLOC1S3,
ANKRD27,
BLOC1S6
|
GO:0035655
|
BP
|
interleukin-18-mediated signaling pathway
|
A series of molecular signals initiated by the binding of interleukin-18 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
|
PDGFB,
AKT1,
IL18R1,
IL18
|
GO:0035665
|
BP
|
TIRAP-dependent toll-like receptor 4 signaling pathway
|
Any series of molecular signals generated as a consequence of binding to a toll-like receptor 4 where the TIRAP/MAL adaptor mediates transduction of the signal. Toll-like 4 receptors are pattern recognition receptors that bind bacterial lipopolysaccharide (LPS) to initiate an innate immune response.
|
TIRAP
|
GO:0035666
|
BP
|
TRIF-dependent toll-like receptor signaling pathway
|
Any series of molecular signals generated as a consequence of binding to a toll-like receptor where the TRIF adaptor mediates transduction of the signal. Toll-like receptors directly bind pattern motifs from a variety of microbial sources to initiate innate immune response.
|
TLR4,
TLR3,
CD14,
UBC,
UBE2D3,
RPS27A,
UBA52,
FADD,
BIRC3,
RIPK1,
CASP8,
TANK,
TBK1
|
GO:0035672
|
BP
|
oligopeptide transmembrane transport
|
The directed movement of an oligopeptide across a membrane by means of some agent such as a transporter or pore. Oligopeptides are molecules that contain a small number (2 to 20) of amino-acid residues connected by peptide linkages.
|
CDH17
|
GO:0035674
|
BP
|
tricarboxylic acid transmembrane transport
|
The process in which tricarboxylic acids are transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
|
SLC25A1
|
GO:0035684
|
BP
|
helper T cell extravasation
|
The migration of a helper T cell from the blood vessels into the surrounding tissue. A helper T-cell is an effector T cell that provides help in the form of secreted cytokines to other immune cells.
|
CCL2
|
GO:0035690
|
BP
|
cellular response to drug
|
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.
|
PPP1R12A,
TLR3,
EGFR,
MYC,
IL1B,
TFRC,
MT2A,
PRNP,
TP53,
EDN1,
TH,
HSP90AB1,
QDPR,
FBP1,
RAP2A,
UMPS,
CCL4,
CCL2,
NME1,
MT3,
CAD,
PPM1F,
PRKAA2,
RAP1A,
GPLD1,
PPAT,
MEF2C,
PPP3CA,
KCNH2,
EIF2B5,
GAS6,
ANKRD1,
ADIPOQ,
ADSSL1,
RNF149,
PPM1E,
PPP1R14A,
RBM22
|
GO:0035691
|
BP
|
macrophage migration inhibitory factor signaling pathway
|
A series of molecular signals initiated by the binding of macrophage migration inhibitory factor to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
|
CD74
|
GO:0035694
|
BP
|
mitochondrial protein catabolic process
|
The chemical reactions and pathways resulting in the breakdown of a mitochondrial protein. This process is necessary to maintain the healthy state of mitochondria and is thought to occur via the induction of an intramitochondrial lysosome-like organelle that acts to eliminate the damaged oxidised mitochondrial proteins without destroying the mitochondrial structure.
|
BNIP3L,
BNIP3,
SPATA18,
YME1L1
|
GO:0035695
|
BP
|
mitophagy by induced vacuole formation
|
The process in which cells degrade mitochondria by inducing a vacuole-like structure which directly engulfs and degrades the unhealthy mitochondria by accumulating lysosomes.
|
SPATA18
|
GO:0035701
|
BP
|
hematopoietic stem cell migration
|
The orderly movement of a hematopoietic stem cell from one site to another. A hematopoietic stem cell is a cell from which all cells of the lymphoid and myeloid lineages develop, including blood cells and cells of the immune system.
|
KIT,
GPLD1
|
GO:0035709
|
BP
|
memory T cell activation
|
The change in morphology and behavior of a memory T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.
|
TNFSF4
|
GO:0035711
|
BP
|
T-helper 1 cell activation
|
The change in morphology and behavior of a T-helper 1 cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.
|
HMGB1,
CEBPB
|
GO:0035712
|
BP
|
T-helper 2 cell activation
|
The change in morphology and behavior of a T helper 2 cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.
|
TNFSF4
|
GO:0035713
|
BP
|
response to nitrogen dioxide
|
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrogen dioxide (NO2) stimulus.
|
TNFSF4
|
GO:0035714
|
BP
|
cellular response to nitrogen dioxide
|
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrogen dioxide (NO2) stimulus.
|
TNFSF4
|
GO:0035720
|
BP
|
intraciliary anterograde transport
|
The directed movement of large protein complexes along microtubules from the cell body toward the tip of a cilium (also called flagellum), mediated by motor proteins.
|
IFT122
|
GO:0035721
|
BP
|
intraciliary retrograde transport
|
The directed movement of large protein complexes along microtubules from the tip of a cilium (also called flagellum) toward the cell body, mediated by motor proteins.
|
IFT43,
IFT122,
WDR35
|
GO:0035722
|
BP
|
interleukin-12-mediated signaling pathway
|
A series of molecular signals initiated by the binding of interleukin-12 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
|
JAK2,
IL12RB1,
PLCB1
|
GO:0035723
|
BP
|
interleukin-15-mediated signaling pathway
|
A series of molecular signals initiated by the binding of interleukin-15 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
|
PLCB1
|
GO:0035725
|
BP
|
sodium ion transmembrane transport
|
A process in which a sodium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
|
KCNK1,
SLC3A2,
SCNN1A,
SLC6A8,
TRAPPC10,
SCNN1G,
SLC20A2,
PKD2,
SHROOM2,
SCN9A,
ASIC2,
ANO6,
TRPM4,
SLC20A1,
SLC5A5,
SLC24A3,
SLC23A2,
ASIC3,
SLC4A4
|
GO:0035726
|
BP
|
common myeloid progenitor cell proliferation
|
The multiplication or reproduction of common myeloid progenitor cells, resulting in the expansion of a cell population. A common myeloid progenitor cell is a progenitor cell committed to the myeloid lineage.
|
GSTP1,
NR4A3
|
GO:0035729
|
BP
|
cellular response to hepatocyte growth factor stimulus
|
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hepatocyte growth factor stimulus.
|
NRP1,
IL6,
TDGF1,
HGF,
CREB1,
IL10,
GCLC,
GCLM,
GSK3B,
RELA,
SIRT2
|
GO:0035732
|
BP
|
nitric oxide storage
|
The accumulation and maintenance in cells or tissues of nitric oxide (NO). Nitric oxide is stored in the form of dinitrosyl-iron complexes, which are stabilized, and possibly sequestered, by binding to glutathione S-transferase proteins.
|
GSTP1
|
GO:0035733
|
BP
|
hepatic stellate cell activation
|
A change in the morphology or behavior of a hepatic stellate cell resulting from exposure to a cytokine, chemokine, hormone, cellular ligand or soluble factor.
|
GCLM
|
GO:0035735
|
BP
|
intraciliary transport involved in cilium morphogenesis
|
The bidirectional movement of large protein complexes along microtubules within a cilium that contributes to cilium morphogenesis.
|
PCM1,
IFT81,
IFT74,
IFT122,
SSX2IP
|
GO:0035743
|
BP
|
CD4-positive, alpha-beta T cell cytokine production
|
Any process that contributes to cytokine production by a CD4-positive, alpha-beta T cell.
|
CD55
|
GO:0035747
|
BP
|
natural killer cell chemotaxis
|
The directed movement of a natural killer cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).
|
PIK3CD,
PIK3CG
|
GO:0035750
|
BP
|
protein localization to myelin sheath abaxonal region
|
Any process in which a protein is transported to, and/or maintained in, the abaxonal region of the myelin sheath. The abaxonal region is the region of the myelin sheath furthest from the axon.
|
MPP5
|
GO:0035751
|
BP
|
regulation of lysosomal lumen pH
|
Any process that modulates the pH of the lysosomal lumen, measured by the concentration of the hydrogen ion.
|
TMEM165
|
GO:0035752
|
BP
|
lysosomal lumen pH elevation
|
Any process that increases the pH of the lysosomal lumen, measured by the concentration of the hydrogen ion.
|
CLN3
|
GO:0035754
|
BP
|
B cell chemotaxis
|
The directed movement of a B cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).
|
PIK3CD,
CH25H,
GAS6,
HSD3B7
|
GO:0035767
|
BP
|
endothelial cell chemotaxis
|
The directed movement of an endothelial cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).
|
NRP1,
PLEKHG5,
VEGFA,
NR4A1,
EGR3,
CORO1B
|
GO:0035771
|
BP
|
interleukin-4-mediated signaling pathway
|
A series of molecular signals initiated by the binding of interleukin-4 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
|
IL4R,
JAK3
|
GO:0035773
|
BP
|
insulin secretion involved in cellular response to glucose stimulus
|
The regulated release of proinsulin from secretory granules (B granules) in the B cells of the pancreas; accompanied by cleavage of proinsulin to form mature insulin, in response to a glucose stimulus.
|
RAF1,
RAB11B,
RAB11FIP2
|
GO:0035774
|
BP
|
positive regulation of insulin secretion involved in cellular response to glucose stimulus
|
Any process that increases the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose.
|
GCG,
CFTR,
SRI,
OXCT1,
GPLD1,
STX4,
HIF1A,
TRPM4,
BAD,
NR1H4,
PHPT1,
GPR27
|
GO:0035783
|
BP
|
CD4-positive, alpha-beta T cell costimulation
|
The process of providing, via surface-bound receptor-ligand pairs, a second, antigen-independent, signal in addition to that provided by the T cell receptor to augment CD4-positive, alpha-beta T cell activation.
|
TNFSF4
|
GO:0035789
|
BP
|
metanephric mesenchymal cell migration
|
The orderly movement of undifferentiated metanephric mesenchymal cells (precursors to metanephric mesangial cells) from the mesenchyme into the cleft of the developing glomerulus, during development of the metanephros.
|
PDGFRB
|
GO:0035790
|
BP
|
platelet-derived growth factor receptor-alpha signaling pathway
|
A series of molecular signals initiated by the binding of a ligand to an alpha-type platelet-derived growth factor receptor (PDGFalpha) on the surface of a signal-receiving cell, and ending with regulation of a downstream cellular process, e.g. transcription.
|
PDGFRA
|
GO:0035791
|
BP
|
platelet-derived growth factor receptor-beta signaling pathway
|
A series of molecular signals initiated by the binding of a ligand to a beta-type platelet-derived growth factor receptor (PDGFbeta) on the surface of a signal-receiving cell, and ending with regulation of a downstream cellular process, e.g. transcription.
|
PDGFRB
|
GO:0035793
|
BP
|
positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway
|
Any process that increases the frequency, rate or extent of metanephric mesenchymal cell migration as a result of the series of molecular signals generated as a consequence of a platelet-derived growth factor receptor-beta binding to one of its physiological ligands.
|
PDGFB,
PDGFA,
PDGFRB
|
GO:0035794
|
BP
|
positive regulation of mitochondrial membrane permeability
|
Any process that increases the frequency, rate or extent of the passage or uptake of molecules by the mitochondrial membrane.
|
HEBP2
|
GO:0035799
|
BP
|
ureter maturation
|
A developmental process, independent of morphogenetic (shape) change, that is required for the ureter to attain its fully functional state. The ureter is a muscular tube that transports urine from the kidney to the urinary bladder or from the Malpighian tubule to the hindgut.
|
ALDH1A2
|
GO:0035802
|
BP
|
adrenal cortex formation
|
The process that gives rise to the adrenal cortex. This process pertains to the initial formation of a structure from unspecified parts. The adrenogonadal primordium from which the adrenal cortex is formed derives from a condensation of coelomic epithelial cells (the urogenital ridge; the same structure from which gonads and kidney also originate).
|
WT1,
CITED2
|
GO:0035803
|
BP
|
egg coat formation
|
Construction of an egg coat, a specialized extracellular matrix that surrounds the ovum of animals. The egg coat provides structural support and can play an essential role in oogenesis, fertilization and early development.
|
ZP3
|
GO:0035810
|
BP
|
positive regulation of urine volume
|
Any process that increases the amount of urine excreted from the body over a unit of time.
|
EDN1,
DRD2,
NPPB,
NPR3,
BTC,
OPRL1,
HYAL2,
HAS2,
INPP5K
|
GO:0035811
|
BP
|
negative regulation of urine volume
|
Any process that decreases the amount of urine excreted from the body over a unit of time.
|
AVPR2
|
GO:0035813
|
BP
|
regulation of renal sodium excretion
|
Any process that modulates the amount of sodium excreted in urine over a unit of time.
|
AGT,
AGTR1
|
GO:0035814
|
BP
|
negative regulation of renal sodium excretion
|
Any process that decreases the amount of sodium excreted in urine over a unit of time.
|
COMT,
AVPR2,
ADORA1,
SPX
|
GO:0035815
|
BP
|
positive regulation of renal sodium excretion
|
Any process that increases the amount of sodium excreted in urine over a unit of time.
|
AGT,
EDN1,
DRD2,
NPPB,
AGTR2
|
GO:0035822
|
BP
|
gene conversion
|
A DNA recombination process that results in the unidirectional transfer of genetic material from a donor sequence to a highly homologous acceptor.
|
NUCKS1
|
GO:0035844
|
BP
|
cloaca development
|
The process whose specific outcome is the progression of the cloaca over time, from it's formation to the mature structure. The cloaca is the common chamber into which intestinal, genital and urinary canals open in vertebrates.
|
AHI1
|
GO:0035845
|
BP
|
photoreceptor cell outer segment organization
|
A process that is carried out at the cellular level and results in the assembly, arrangement of constituent parts, or disassembly of the outer segment of a photoreceptor cell, a sensory cell that reacts to the presence of light. The outer segment of the photoreceptor cell contains the light-absorbing materials.
|
AHI1
|
GO:0035855
|
BP
|
megakaryocyte development
|
The process whose specific outcome is the progression of a megakaryocyte cell over time, from its formation to the mature structure. Megakaryocyte development does not include the steps involved in committing a cell to a megakaryocyte fate. A megakaryocyte is a giant cell 50 to 100 micron in diameter, with a greatly lobulated nucleus, found in the bone marrow.
|
MEIS1,
KIT,
TAL1,
PTPN11,
EP300,
ABI1,
WASF2
|
GO:0035860
|
BP
|
glial cell-derived neurotrophic factor receptor signaling pathway
|
The series of molecular signals generated as a consequence of a glial cell-derived neurotrophic factor receptor binding to one of its physiological ligands.
|
SULF2,
SULF1
|
GO:0035863
|
BP
|
dITP catabolic process
|
The chemical reactions and pathways resulting in the breakdown of dITP, a deoxyinosine phosphate compound having a triphosphate group at the 5'-position.
|
NUDT16
|
GO:0035864
|
BP
|
response to potassium ion
|
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a potassium ion stimulus.
|
GNRH1
|
GO:0035865
|
BP
|
cellular response to potassium ion
|
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a potassium ion stimulus.
|
CYP11B1,
CYP11B2,
HSF1,
PPARGC1A
|
GO:0035871
|
BP
|
protein K11-linked deubiquitination
|
A protein deubiquitination process in which a K11-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 11 of the ubiquitin monomers, is removed from a protein.
|
TNFAIP3,
OTUD7B,
OTUB2,
VCPIP1
|
GO:0035873
|
BP
|
lactate transmembrane transport
|
The directed movement of lactate across a membrane by means of some agent such as a transporter or pore. Lactate is 2-hydroxypropanoate, CH3-CHOH-COOH; L(+)-lactate is formed by anaerobic glycolysis in animal tissues, and DL-lactate is found in sour milk, molasses and certain fruit juices.
|
SLC16A7
|
GO:0035878
|
BP
|
nail development
|
The process whose specific outcome is the progression of a nail over time, from its formation to the mature structure. A nail is a horn-like envelope covering the outer end of a finger or toe, and consists of the nail plate, the nail matrix and the nail bed below it, and the grooves surrounding it.
|
ITGB4,
ITGA6
|
GO:0035879
|
BP
|
plasma membrane lactate transport
|
The directed movement of lactate across a plasma membrane.
|
SLC16A6,
SLC16A3,
SLC16A7,
SLC16A12
|
GO:0035880
|
BP
|
embryonic nail plate morphogenesis
|
The process, occurring in the embryo, by which the anatomical structures of a nail plate are generated and organized. The nail plate is the hard and translucent portion of the nail, composed of keratin, and serves to protect the tips of digits.
|
FZD6
|
GO:0035886
|
BP
|
vascular smooth muscle cell differentiation
|
The process in which a relatively unspecialized cell acquires specialized features of a vascular smooth muscle cell.
|
PITX2,
EPC1
|
GO:0035897
|
BP
|
proteolysis in other organism
|
The chemical reactions and pathways performed by an organism resulting in the hydrolysis of proteins in another organism by cleavage of their peptide bonds.
|
MAP2K7,
MAP2K2,
MAP2K6,
MAP2K1
|
GO:0035900
|
BP
|
response to isolation stress
|
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lack of contact with other members of the same species.
|
TH,
NAPEPLD
|
GO:0035902
|
BP
|
response to immobilization stress
|
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of being rendered immobile.
|
FOS,
TGFB1,
CYP1A1,
GPI,
TH,
GAL,
PPARG,
HNMT,
NR0B1
|
GO:0035904
|
BP
|
aorta development
|
The progression of the aorta over time, from its initial formation to the mature structure. An aorta is an artery that carries blood from the heart to other parts of the body.
|
SMAD6,
LOX,
NDST1,
AP2B1,
LRP2,
LOXL1,
PKD2,
LTBP1,
TAB1,
PRICKLE1,
DCTN5,
ADAMTS6,
SUFU,
PLXND1
|
GO:0035909
|
BP
|
aorta morphogenesis
|
The process in which the anatomical structures of an aorta are generated and organized. An aorta is an artery that carries blood from the heart to other parts of the body.
|
TBX1,
PDGFRB,
JAG1,
NPRL3,
CHD7
|
GO:0035910
|
BP
|
ascending aorta morphogenesis
|
The process in which the anatomical structures of the ascending aorta are generated and organized. The ascending aorta is the portion of the aorta in a two-pass circulatory system that lies between the heart and the arch of aorta. In a two-pass circulatory system blood passes twice through the heart to supply the body once.
|
TGFB2,
SOX4,
HES1
|
GO:0035912
|
BP
|
dorsal aorta morphogenesis
|
The process in which the anatomical structures of the dorsal aorta are generated and organized. The dorsal aorta is a blood vessel in a single-pass circulatory system that carries oxygenated blood from the gills to the rest of the body. In a single-pass circulatory system blood passes once through the heart to supply the body once.
|
BMPR1A,
DLL4,
HEY1
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GO:0035914
|
BP
|
skeletal muscle cell differentiation
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The process in which a relatively unspecialized cell acquires specialized features of a skeletal muscle cell, a somatic cell located in skeletal muscle.
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NUPR1,
FOS,
RB1,
EGR2,
EEF2,
EGR1,
ATF3,
FOXN2,
NOTCH1,
EMD,
SOX8,
BTG2,
MEF2C,
MEF2D,
ANKRD1,
HLF,
HIVEP3,
ZNF689,
HEYL,
HMG20B,
MAFF,
PLAGL1
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GO:0035921
|
BP
|
desmosome disassembly
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The controlled breakdown of a desmosome. A desmosome is a patch-like intercellular junction found in vertebrate tissues, consisting of parallel zones of two cell membranes, separated by an space of 25-35 nm, and having dense fibrillar plaques in the subjacent cytoplasm.
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SNAI2
|
GO:0035922
|
BP
|
foramen ovale closure
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The morphogenetic process in which the foramen ovale closes after birth, to prevent blood flow between the right and left atria. In the fetal heart, the foramen ovale allows blood to enter the left atrium from the right atrium. Closure of the foramen ovale after birth stops this blood flow.
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GJA5
|
GO:0035924
|
BP
|
cellular response to vascular endothelial growth factor stimulus
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Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vascular endothelial growth factor stimulus.
|
ITGB1BP1,
NRP1,
ERN1,
HSPB1,
MT1G,
VEGFA,
VCAM1,
NR4A1,
AKT1,
FLT4,
NOTCH1,
MAPKAPK2,
GAS1,
EGR3,
PRKD1,
MAPK14,
PRKD2,
DLL4
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GO:0035926
|
BP
|
chemokine (C-C motif) ligand 2 secretion
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The regulated release of chemokine (C-C motif) ligand 2 (CCL2) from a cell.
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F2RL1,
FOXP1
|
GO:0035927
|
BP
|
RNA import into mitochondrion
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The directed movement of RNA from the cytoplasm into a mitochondrion.
|
PNPT1
|
GO:0035928
|
BP
|
rRNA import into mitochondrion
|
The directed movement of rRNA, ribosomal ribonucleic acid, from the cytoplasm into a mitochondrion.
|
PNPT1
|
GO:0035932
|
BP
|
aldosterone secretion
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The regulated release of aldosterone into the circulatory system. Aldosterone is a pregnane-based steroid hormone produced by the outer-section (zona glomerulosa) of the adrenal cortex in the adrenal gland, and acts on the distal tubules and collecting ducts of the kidney to cause the conservation of sodium, secretion of potassium, increased water retention, and increased blood pressure. The overall effect of aldosterone is to increase reabsorption of ions and water in the kidney.
|
AGTR2
|
GO:0035945
|
BP
|
mitochondrial ncRNA surveillance
|
The set of processes involved in identifying and degrading defective or aberrant non-coding RNA transcripts (ncRNAs) within the mitochondrion.
|
SUPV3L1
|
GO:0035946
|
BP
|
mitochondrial mRNA surveillance
|
The set of processes involved in identifying and degrading messenger RNA (mRNA) within the mitochondrion.
|
SUPV3L1
|
GO:0035947
|
BP
|
regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter
|
Any process that modulates the frequency, rate or extent of gluconeogenesis, by regulation of transcription from an RNA polymerase II promoter.
|
NR1D1,
FOXO1
|
GO:0035948
|
BP
|
positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter
|
Any process that activates or increases the frequency, rate or extent of gluconeogenesis by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
GCG,
KAT2B
|
GO:0035963
|
BP
|
cellular response to interleukin-13
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Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-13 stimulus.
|
ALOX15,
SHPK
|
GO:0035964
|
BP
|
COPI-coated vesicle budding
|
The evagination of a Golgi membrane, resulting in formation of a COPI-coated vesicle.
|
TMED10
|