GO ID |
Ontology |
GO Term |
Term Definition |
Proteins |
GO:0032286
|
BP
|
central nervous system myelin maintenance
|
The process in which the structure and material content of mature central nervous system myelin is kept in a functional state.
|
CLU,
PTEN,
FA2H,
MYRF
|
GO:0032287
|
BP
|
peripheral nervous system myelin maintenance
|
The process in which the structure and material content of mature peripheral nervous system myelin is kept in a functional state.
|
AKT1,
AKT2,
FA2H,
MPP5,
SH3TC2,
NDRG1
|
GO:0032288
|
BP
|
myelin assembly
|
The process in which the wraps of cell membrane that constitute myelin are laid down around an axon in the central or peripheral nervous system.
|
GPC1,
ILK,
MTMR2,
MPP5,
PIKFYVE
|
GO:0032289
|
BP
|
central nervous system myelin formation
|
The process in which the wraps of cell membrane that constitute myelin are laid down around an axon by an oligodendrocyte in the central nervous system.
|
TLR2,
ERCC2,
TENM4
|
GO:0032290
|
BP
|
peripheral nervous system myelin formation
|
The process in which the wraps of cell membrane that constitute myelin are laid down around an axon by an oligodendrocyte in the peripheral nervous system.
|
DICER1
|
GO:0032298
|
BP
|
positive regulation of DNA-dependent DNA replication initiation
|
Any process that activates or increases the frequency, rate or extent of initiation of DNA-dependent DNA replication.
|
CDK2
|
GO:0032304
|
BP
|
negative regulation of icosanoid secretion
|
Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of an icosanoid from a cell.
|
AGTR2
|
GO:0032308
|
BP
|
positive regulation of prostaglandin secretion
|
Any process that activates or increases the frequency, rate or extent of the regulated release of a prostaglandin from a cell.
|
IL1B,
EDN1,
MAP2K6,
P2RX4
|
GO:0032310
|
BP
|
prostaglandin secretion
|
The regulated release of a prostaglandin, any of a group of biologically active metabolites which contain a cyclopentane ring, from a cell or a tissue.
|
ABCC4,
LEP
|
GO:0032324
|
BP
|
molybdopterin cofactor biosynthetic process
|
The chemical reactions and pathways resulting in the formation of the molybdopterin cofactor (Moco), essential for the catalytic activity of some enzymes, e.g. sulfite oxidase, xanthine dehydrogenase, and aldehyde oxidase. The cofactor consists of a mononuclear molybdenum (Mo-molybdopterin) or tungsten ion (W-molybdopterin) coordinated by one or two molybdopterin ligands.
|
MOCOS,
GPHN
|
GO:0032330
|
BP
|
regulation of chondrocyte differentiation
|
Any process that modulates the frequency, rate or extent of chondrocyte differentiation.
|
SHOX2,
MAF,
CTGF,
GLG1,
LNP,
TRPS1
|
GO:0032331
|
BP
|
negative regulation of chondrocyte differentiation
|
Any process that stops, prevents, or reduces the frequency, rate or extent of chondrocyte differentiation.
|
SNAI2,
GREM1,
GLI2,
PTHLH,
BMP4,
CTNNB1,
TGFBR1,
GDF5,
SOX9,
ADAMTS12,
EFEMP1,
ADAMTS7
|
GO:0032332
|
BP
|
positive regulation of chondrocyte differentiation
|
Any process that activates or increases the frequency, rate or extent of chondrocyte differentiation.
|
FGF18,
GLI3,
BMP6,
SOX6,
GDF5,
SOX9,
SMAD3,
RELA,
ZBTB16,
RUNX2,
LOXL2
|
GO:0032342
|
BP
|
aldosterone biosynthetic process
|
The chemical reactions and pathways resulting in the formation of aldosterone, a corticosteroid hormone that is produced by the zona glomerulosa of the adrenal cortex and regulates salt (sodium and potassium) and water balance.
|
CYP11B1,
CYP11B2
|
GO:0032348
|
BP
|
negative regulation of aldosterone biosynthetic process
|
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of aldosterone.
|
BMP2,
DKK3
|
GO:0032349
|
BP
|
positive regulation of aldosterone biosynthetic process
|
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of aldosterone.
|
BMP6
|
GO:0032350
|
BP
|
regulation of hormone metabolic process
|
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving any hormone.
|
TCF7L2
|
GO:0032354
|
BP
|
response to follicle-stimulating hormone
|
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a follicle-stimulating hormone stimulus.
|
ASNS,
SRD5A1,
SRD5A2,
TGFBR3,
PAPPA
|
GO:0032355
|
BP
|
response to estradiol
|
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by estradiol, a C18 steroid hormone hydroxylated at C3 and C17 that acts as a potent estrogen.
|
SOCS2,
DHH,
ALDH1A2,
MBD4,
MBD3,
ASS1,
CST3,
TGFB1,
PENK,
GH1,
CD4,
COL1A1,
CRYAB,
ESR1,
ANXA1,
GPI,
TH,
GSTP1,
PDGFRB,
TFPI,
ESRRA,
PCNA,
EEF2,
ETS1,
AREG,
NQO1,
IGFBP2,
PAM,
NR2F2,
CALR,
DUSP1,
CTGF,
SLC6A1,
OXTR,
CTNNB1,
PTGS2,
STAT3,
OPRL1,
LEP,
ADCYAP1R1,
PTGFR,
CDKN1B,
MMP15,
STAT5B,
CASP9,
BID,
PTEN,
STRN3,
PTCH1,
KCNJ11,
CASP8,
POSTN,
NCOA1,
EZH2,
BAD,
TXNIP,
WFDC1,
DNMT3B
|
GO:0032364
|
BP
|
oxygen homeostasis
|
A homeostatic process involved in the maintenance of an internal steady state of oxygen within an organism or cell.
|
SOD2,
HIF1A
|
GO:0032366
|
BP
|
intracellular sterol transport
|
The directed movement of sterols within cells.
|
NPC2
|
GO:0032367
|
BP
|
intracellular cholesterol transport
|
The directed movement of cholesterol, cholest-5-en-3-beta-ol, within cells.
|
ABCA1,
STAR,
NPC2,
STARD4
|
GO:0032368
|
BP
|
regulation of lipid transport
|
Any process that modulates the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
PARK2
|
GO:0032369
|
BP
|
negative regulation of lipid transport
|
Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
ITGB3,
ITGAV,
NR1H2,
NR1H3
|
GO:0032374
|
BP
|
regulation of cholesterol transport
|
Any process that modulates the frequency, rate or extent of the directed movement of cholesterol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
APOC1,
TSPO
|
GO:0032375
|
BP
|
negative regulation of cholesterol transport
|
Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of cholesterol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
APOA2,
APOC1,
NFKB1
|
GO:0032376
|
BP
|
positive regulation of cholesterol transport
|
Any process that activates or increases the frequency, rate or extent of the directed movement of cholesterol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
NR1H2,
NR1H3,
LIPG
|
GO:0032385
|
BP
|
positive regulation of intracellular cholesterol transport
|
Any process that activates or increases the frequency, rate or extent of the directed movement of cholesterol within cells.
|
SCP2
|
GO:0032386
|
BP
|
regulation of intracellular transport
|
Any process that modulates the frequency, rate or extent of the directed movement of substances within cells.
|
WWC1
|
GO:0032387
|
BP
|
negative regulation of intracellular transport
|
Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances within cells.
|
CRYAB,
MAPT,
MAP1B
|
GO:0032388
|
BP
|
positive regulation of intracellular transport
|
Any process that activates or increases the frequency, rate or extent of the directed movement of substances within cells.
|
CAPN10
|
GO:0032392
|
BP
|
DNA geometric change
|
The process in which a transformation is induced in the geometry of a DNA double helix, resulting in a change in twist, writhe, or both, but with no change in linking number. Includes the unwinding of double-stranded DNA by helicases.
|
HMGB3,
HMGB1,
HMGB2,
MTERF1
|
GO:0032400
|
BP
|
melanosome localization
|
Any process in which a melanosome is transported to, and/or maintained in, a specific location within the cell.
|
RAB27A
|
GO:0032401
|
BP
|
establishment of melanosome localization
|
The directed movement of a melanosome to a specific location.
|
SHROOM2
|
GO:0032402
|
BP
|
melanosome transport
|
The directed movement of melanosomes into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
RAB27B,
RAB27A,
RAB11A,
RAB1A,
DCTN2,
DCTN1,
RAB11B,
BLOC1S3,
BBS7,
BBS2,
MKKS,
BLOC1S6,
MYO5A
|
GO:0032410
|
BP
|
negative regulation of transporter activity
|
Any process that stops or reduces the activity of a transporter.
|
WWP2,
SNCA,
NDFIP1,
NDFIP2,
CTTNBP2NL
|
GO:0032411
|
BP
|
positive regulation of transporter activity
|
Any process that activates or increases the activity of a transporter.
|
SYNGR3,
PON1,
SGK3
|
GO:0032412
|
BP
|
regulation of ion transmembrane transporter activity
|
Any process that modulates the activity of an ion transporter.
|
AHCYL1
|
GO:0032414
|
BP
|
positive regulation of ion transmembrane transporter activity
|
Any process that activates or increases the activity of an ion transporter.
|
WNK3,
WNK1,
TRPC6
|
GO:0032417
|
BP
|
positive regulation of sodium:proton antiporter activity
|
Any process that activates or increases the activity of a sodium:hydrogen antiporter, which catalyzes the reaction: Na+(out) + H+(in) = Na+(in) + H+(out).
|
ACTN4,
CHP1
|
GO:0032418
|
BP
|
lysosome localization
|
Any process in which a lysosome is transported to, and/or maintained in, a specific location.
|
SNAPIN,
BLOC1S1,
LAMTOR1,
LOH12CR1,
BORCS6,
RAB34,
TMEM106B,
ARL8B,
HDAC6
|
GO:0032425
|
BP
|
positive regulation of mismatch repair
|
Any process that activates or increases the frequency, rate or extent of mismatch repair.
|
HMGB1
|
GO:0032429
|
BP
|
regulation of phospholipase A2 activity
|
Any process that modulates the activity of the enzyme phospholipase A2.
|
PPT1
|
GO:0032430
|
BP
|
positive regulation of phospholipase A2 activity
|
Any process that activates or increases the activity of the enzyme phospholipase A2.
|
AGTR1
|
GO:0032431
|
BP
|
activation of phospholipase A2 activity
|
Any process that initiates the activity of the inactive enzyme phospholipase A2.
|
ANG
|
GO:0032434
|
BP
|
regulation of proteasomal ubiquitin-dependent protein catabolic process
|
Any process that modulates the frequency, rate or extent of the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.
|
RAD23A,
RAD23B,
GNA12,
COMMD1,
GLMN,
DDA1,
UBQLN4
|
GO:0032435
|
BP
|
negative regulation of proteasomal ubiquitin-dependent protein catabolic process
|
Any process that stops, prevents, or reduces the frequency, rate or extent of the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.
|
SDCBP,
N4BP1,
HSP90AB1,
FHIT,
MTM1,
HFE,
CCAR2,
SMARCC1,
PBK,
WAC,
BAG5
|
GO:0032436
|
BP
|
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
|
Any process that activates or increases the frequency, rate or extent of the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.
|
AURKA,
SMAD7,
PARK2,
SOCS5,
PSMD10,
IL33,
CLU,
AKT1,
GCLC,
CSNK1A1,
CSNK1D,
CSNK1E,
PSEN1,
GSK3B,
RNF144A,
PLK1,
VCP,
SUMO2,
RACK1,
DAB2,
MDM2,
UBE2V2,
RNF19B,
RNF144B,
BBS7,
SIRT2,
FBXO22,
TRIB2,
PRICKLE1,
TRIB3,
TRIB1,
RNF19A,
PLK2,
RNF14,
STUB1,
ARIH1,
RNF114,
NUB1
|
GO:0032438
|
BP
|
melanosome organization
|
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a melanosome. A melanosome is a tissue-specific, membrane-bounded cytoplasmic organelle within which melanin pigments are synthesized and stored.
|
AP3D1,
RAB29,
SNAPIN,
PMEL,
BLOC1S1,
SHROOM2,
BLOC1S3,
LYST,
BLOC1S6
|
GO:0032439
|
BP
|
endosome localization
|
Any process in which endosomes are transported to, and/or maintained in, a specific location within the cell.
|
LAMTOR1,
ANKFY1,
MYO5B
|
GO:0032446
|
BP
|
protein modification by small protein conjugation
|
A protein modification process in which one or more groups of a small protein, such as ubiquitin or a ubiquitin-like protein, are covalently attached to a target protein.
|
UBD,
ATG10
|
GO:0032455
|
BP
|
nerve growth factor processing
|
The generation of a mature nerve growth factor (NGF) by proteolysis of a precursor.
|
NGF,
FURIN,
PCSK6,
PCSK5
|
GO:0032456
|
BP
|
endocytic recycling
|
The directed movement of membrane-bounded vesicles from recycling endosomes back to the plasma membrane where they are recycled for further rounds of transport.
|
STX6,
RAB11FIP3,
SNX4,
EPS15,
VPS52,
DENND1A,
EHD4,
EPG5,
EHD3
|
GO:0032460
|
BP
|
negative regulation of protein oligomerization
|
Any process that stops, prevents, or reduces the frequency, rate or extent of protein oligomerization.
|
INS,
SORL1
|
GO:0032461
|
BP
|
positive regulation of protein oligomerization
|
Any process that activates or increases the frequency, rate or extent of protein oligomerization.
|
MMP1,
TP53,
CCK,
IDE,
BID,
BAX,
PMAIP1,
TRABD2A,
SH3GLB1,
SNX9
|
GO:0032463
|
BP
|
negative regulation of protein homooligomerization
|
Any process that stops, prevents, or reduces the frequency, rate or extent of protein homooligomerization.
|
CLU
|
GO:0032464
|
BP
|
positive regulation of protein homooligomerization
|
Any process that activates or increases the frequency, rate or extent of protein homooligomerization.
|
BCL2L11,
FAS,
BID,
RACK1,
MIEF2
|
GO:0032465
|
BP
|
regulation of cytokinesis
|
Any process that modulates the frequency, rate or extent of the division of the cytoplasm of a cell and its separation into two daughter cells.
|
AURKA,
PRPF40A,
BRCA2,
CALM2,
PIK3C3,
FLCN,
PIK3R4,
GIT1,
SH3GLB1
|
GO:0032466
|
BP
|
negative regulation of cytokinesis
|
Any process that stops, prevents, or reduces the frequency, rate or extent of the division of the cytoplasm of a cell, and its separation into two daughter cells.
|
E2F8,
TEX14,
AURKB,
ZFYVE19
|
GO:0032467
|
BP
|
positive regulation of cytokinesis
|
Any process that activates or increases the frequency, rate or extent of the division of the cytoplasm of a cell, and its separation into two daughter cells.
|
DRD2,
CDC25B,
SSTR5,
CDC42,
RHOA,
KIF23,
CUL3,
KIF14,
PKN2,
CSPP1,
CENPV,
AURKB,
KIF20B,
PKP4,
CDC6,
RACGAP1,
ECT2,
SPAST
|
GO:0032468
|
BP
|
Golgi calcium ion homeostasis
|
Any process involved in the maintenance of an internal steady state of calcium ions within the Golgi apparatus of a cell or between the Golgi and its surroundings.
|
ATP2C1
|
GO:0032469
|
BP
|
endoplasmic reticulum calcium ion homeostasis
|
Any process involved in the maintenance of an internal steady state of calcium ions within the endoplasmic reticulum of a cell or between the endoplasmic reticulum and its surroundings.
|
BCL2,
ATP2A2,
PSEN1,
BAX,
CAMK2D,
ITPR1,
GRINA,
TMCO1
|
GO:0032470
|
BP
|
positive regulation of endoplasmic reticulum calcium ion concentration
|
Any process that increases the concentration of calcium ions in the endoplasmic reticulum.
|
ATP2A2
|
GO:0032471
|
BP
|
negative regulation of endoplasmic reticulum calcium ion concentration
|
Any process that decreases the concentration of calcium ions in the endoplasmic reticulum.
|
TGM2,
BCAP31,
RAP1GDS1,
BAX
|
GO:0032472
|
BP
|
Golgi calcium ion transport
|
The directed movement of calcium ions (Ca2+) into, out of or within the Golgi apparatus.
|
ATP2C1,
TMEM165
|
GO:0032474
|
BP
|
otolith morphogenesis
|
The process in which the anatomical structures of an otolith are generated and organized.
|
LRIG3,
LRIG1
|
GO:0032479
|
BP
|
regulation of type I interferon production
|
Any process that modulates the frequency, rate, or extent of interferon type I production. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.
|
UBC,
RPS27A,
UBA52
|
GO:0032480
|
BP
|
negative regulation of type I interferon production
|
Any process that stops, prevents, or reduces the frequency, rate, or extent of type I interferon production. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.
|
ISG15,
UBC,
TNFAIP3,
UBA7,
RPS27A,
UBA52,
TRIM25,
MAVS,
TAX1BP1,
NLRC5,
ITCH,
CYLD,
RNF216,
TBK1
|
GO:0032481
|
BP
|
positive regulation of type I interferon production
|
Any process that activates or increases the frequency, rate, or extent of type I interferon production. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.
|
POLR1C,
POLR3G,
CRCP,
CD14,
IRF1,
XRCC5,
PLCG2,
POLR2E,
NFKB1,
CTNNB1,
SYK,
MRE11A,
IRAK1,
POLR2K,
POLR2L,
PRKDC,
RELA,
EP300,
IFI16,
LRRFIP1,
CREBBP,
POLR3GL,
POLR3C,
POLR3F,
DHX36,
POLR3B,
TBK1,
PTPN22,
POLR1D,
POLR3K
|
GO:0032482
|
BP
|
Rab protein signal transduction
|
A series of molecular signals within the cell that are mediated by a member of the Rab family of proteins switching to a GTP-bound active state.
|
GDI1
|
GO:0032483
|
BP
|
regulation of Rab protein signal transduction
|
Any process that modulates the frequency, rate or extent of Rab protein signal transduction.
|
DENND1A
|
GO:0032485
|
BP
|
regulation of Ral protein signal transduction
|
Any process that modulates the frequency, rate or extent of Ral protein signal transduction.
|
RALGPS1,
RALGPS2
|
GO:0032486
|
BP
|
Rap protein signal transduction
|
A series of molecular signals within the cell that are mediated by a member of the Rap family of proteins switching to a GTP-bound active state.
|
RAP2A,
RAP2B,
RAP1A,
RAPGEF1,
PLK2
|
GO:0032487
|
BP
|
regulation of Rap protein signal transduction
|
Any process that modulates the frequency, rate or extent of Rap protein signal transduction.
|
TIMP2,
RDX,
KIF14
|
GO:0032489
|
BP
|
regulation of Cdc42 protein signal transduction
|
Any process that modulates the frequency, rate or extent of Cdc42 protein signal transduction.
|
ABCA1,
APOA1,
APOE,
APOC3
|
GO:0032490
|
BP
|
detection of molecule of bacterial origin
|
The series of events in which a stimulus from a molecule of bacterial origin is received and converted into a molecular signal.
|
C4A,
C4B
|
GO:0032494
|
BP
|
response to peptidoglycan
|
Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptidoglycan stimulus. Peptidoglycan is a bacterial cell wall macromolecule.
|
IL6,
C5AR1,
IRAK3
|
GO:0032495
|
BP
|
response to muramyl dipeptide
|
Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a muramyl dipeptide stimulus. Muramyl dipeptide is derived from peptidoglycan.
|
TNFAIP3,
NOTCH1,
JAG1,
RELA,
MAPK14
|
GO:0032496
|
BP
|
response to lipopolysaccharide
|
Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria.
|
TLR4,
TNFRSF11B,
PTGES,
TNFRSF10C,
CYP27B1,
JAK2,
TNFRSF21,
FOS,
GNRH1,
PENK,
PPBP,
PF4,
SLPI,
APOB,
CYP1A1,
S100A8,
MPO,
ALPL,
EDN1,
JUN,
TH,
DCN,
NGFR,
CXCL1,
SPARC,
CNP,
MGST1,
HSPD1,
BCR,
ALAD,
SELE,
PLCG2,
IFNAR1,
JUNB,
JUND,
VCAM1,
CXCL2,
CNR1,
C5AR1,
COMT,
F2R,
FAS,
HMGB2,
CD27,
MAOB,
TNFRSF8,
IL12A,
CASP1,
CD6,
S100A7,
ADM,
PTGS2,
PTGER4,
PCK1,
LTBR,
SNCA,
CXCL5,
PTGFR,
PTGER2,
NOTCH1,
MAPKAPK2,
SLC11A1,
IRAK1,
CASP9,
TIRAP,
ADAM17,
CXCL6,
TJP1,
LOXL1,
ABR,
MTA1,
HDAC1,
CASP8,
PCK2,
HDAC2,
TNFRSF25,
PELI1,
TRIB1,
MGST2,
CITED1,
TRIM6,
FOXP1,
NOCT,
PTPN22,
IRAK3,
TNFRSF11A,
DUSP10
|
GO:0032497
|
BP
|
detection of lipopolysaccharide
|
The series of events in which a lipopolysaccharide stimulus is received by a cell and converted into a molecular signal. Lipopolysaccharide is a major component of the cell wall of gram-negative bacteria.
|
TLR4,
SCARB1
|
GO:0032502
|
BP
|
developmental process
|
A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition.
|
COMT,
NUDCD2,
RNPC3,
CITED4
|
GO:0032506
|
BP
|
cytokinetic process
|
A cellular process that is involved in cytokinesis (the division of the cytoplasm of a cell and its separation into two daughter cells).
|
SPAST
|
GO:0032507
|
BP
|
maintenance of protein location in cell
|
Any process in which a protein is maintained in a specific location within, or in the membrane of, a cell, and is prevented from moving elsewhere.
|
CD4,
CAV1,
DBN1
|
GO:0032508
|
BP
|
DNA duplex unwinding
|
The process in which interchain hydrogen bonds between two strands of DNA are broken or 'melted', generating a region of unpaired single strands.
|
DDX3X,
CHD1,
CHD2,
NBN,
RECQL4,
FSBP,
ANXA1,
XRCC5,
MCM3,
MCM5,
RECQL,
ATRX,
MRE11A,
DNA2,
BLM,
G3BP1,
GINS1,
CHD4,
SETX,
SUPV3L1,
ASCC3,
FBXO18,
RAD50,
GINS4,
PIF1,
CHD8,
POT1,
RUVBL2,
GINS2,
RUVBL1,
RAD54B
|
GO:0032510
|
BP
|
endosome to lysosome transport via multivesicular body sorting pathway
|
The directed movement of substances from endosomes to lysosomes by a pathway in which molecules are sorted into multivesicular bodies, which then fuse with the lysosome.
|
VPS4B,
LYST
|
GO:0032514
|
BP
|
positive regulation of protein phosphatase type 2B activity
|
Any process that activates or increases the activity of the enzyme protein phosphatase type 2B.
|
AKAP6
|
GO:0032515
|
BP
|
negative regulation of phosphoprotein phosphatase activity
|
Any process that stops or reduces the activity of a phosphoprotein phosphatase.
|
PPP1R11,
PPP1R15A,
PPP2R4,
RGN
|
GO:0032516
|
BP
|
positive regulation of phosphoprotein phosphatase activity
|
Any process that activates or increases the activity of a phosphoprotein phosphatase.
|
JAK2,
PPP1R15A,
HSP90AB1,
PDGFRB,
AGTR2,
CALM2,
PPP2R4,
MAGI2
|
GO:0032525
|
BP
|
somite rostral/caudal axis specification
|
The establishment, maintenance and elaboration of the rostro-caudal axis of a somite, prior to the morphological formation of a somite boundary.
|
KDM6A,
SMAD4,
TMED2
|
GO:0032526
|
BP
|
response to retinoic acid
|
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a retinoic acid stimulus.
|
PTGES,
DKK1,
RBP4,
PDGFRB,
CTSH,
IGF2R,
IGFBP2,
BMP6,
DUSP1,
TIE1,
SREBF1,
HSD17B2,
PPARG,
CLK2,
ASCL1,
PTCH1,
NCOA1,
IGFBP7,
MICB,
AQP3,
DNAAF2
|
GO:0032527
|
BP
|
protein exit from endoplasmic reticulum
|
The directed movement of proteins from the endoplasmic reticulum.
|
RANGRF
|
GO:0032528
|
BP
|
microvillus organization
|
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a microvillus, a thin cylindrical membrane-covered projection on the surface of a cell.
|
PTPN11,
GLDN
|
GO:0032532
|
BP
|
regulation of microvillus length
|
A process that modulates the length of a microvillus.
|
EZR,
PLS1,
TWF2,
CDHR2
|
GO:0032534
|
BP
|
regulation of microvillus assembly
|
A process that modulates the formation of a microvillus.
|
ATP8B1,
PLD1,
FSCN1
|
GO:0032535
|
BP
|
regulation of cellular component size
|
A process that modulates the size of a cellular component.
|
PTEN
|
GO:0032543
|
BP
|
mitochondrial translation
|
The chemical reactions and pathways resulting in the formation of a protein in a mitochondrion. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein; the mitochondrion has its own ribosomes and transfer RNAs, and uses a genetic code that differs from the nuclear code.
|
MRPS12,
GATC,
GATB,
NDUFA7,
HARS,
MRPS21,
MRPS34,
MRPL23,
MRPL51,
PTCD3,
MRPL57,
QRSL1,
MRPL47,
MRPS18A,
MRPL16,
MRPS2,
MRPS18B
|
GO:0032570
|
BP
|
response to progesterone
|
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a progesterone stimulus.
|
CLDN4,
TLR2,
FOS,
TGFB1,
TYMS,
GPI,
THBS1,
CCL2,
FOSL1,
TSPO,
OXTR,
SREBF1,
PTGER2,
FOSB,
TGFB2,
CAV1,
RELA,
NR1H3,
DSG2,
NCOA1,
BAD,
TXNIP
|
GO:0032571
|
BP
|
response to vitamin K
|
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin K stimulus.
|
BGLAP
|
GO:0032596
|
BP
|
protein transport into membrane raft
|
The directed movement of a protein into a membrane raft. Membrane rafts are small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes.
|
RFTN1,
RFTN2
|
GO:0032597
|
BP
|
B cell receptor transport into membrane raft
|
The directed movement of a B cell receptor into a membrane raft.
|
CD24
|