GO ID |
Ontology |
GO Term |
Term Definition |
Proteins |
GO:0033209
|
BP
|
tumor necrosis factor-mediated signaling pathway
|
A series of molecular signals initiated by the binding of a tumor necrosis factor to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
|
PSMD11,
PSMD12,
TNFRSF11B,
TNFSF11,
TNFRSF10C,
PSMD3,
FOXO3,
JAK2,
TNFRSF21,
PSMD10,
TNFSF13,
TNF,
KRT18,
KRT8,
NGFR,
UBC,
PSMC3,
TNFRSF1B,
PSMB1,
TNFSF4,
FAS,
PSMA1,
PSMA2,
PSMA3,
PSMA4,
CD27,
PSMB8,
PSMB9,
PSMB4,
PSMB5,
TNFRSF8,
CD40LG,
PSMC2,
LTBR,
PSMB10,
PSMC4,
PSMB3,
PSMD7,
PSME3,
PSMC1,
PSMC6,
RPS27A,
UBA52,
ADAM17,
PSMD2,
BIRC3,
RIPK1,
PSME4,
TRADD,
EDARADD,
TNFRSF25,
TNFRSF12A,
TNFRSF19,
PYCARD,
TNFSF13B,
TNFRSF11A
|
GO:0033210
|
BP
|
leptin-mediated signaling pathway
|
A series of molecular signals initiated by the binding of leptin to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. Leptin is a hormone manufactured primarily in the adipocytes of white adipose tissue, and the level of circulating leptin is directly proportional to the total amount of fat in the body.
|
MT3,
STAT3,
LEP,
LEPR,
ADIPOR1
|
GO:0033211
|
BP
|
adiponectin-activated signaling pathway
|
A series of molecular signals initiated by the binding of adiponectin to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
|
ACSL1,
ADIPOQ,
SLC27A1,
ADIPOR2,
ADIPOR1
|
GO:0033227
|
BP
|
dsRNA transport
|
The directed movement of dsRNA, double-stranded ribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
FLOT1,
RFTN1,
RFTN2
|
GO:0033233
|
BP
|
regulation of protein sumoylation
|
Any process that modulates the frequency, rate or extent of the addition of SUMO groups to a protein.
|
EGR1
|
GO:0033234
|
BP
|
negative regulation of protein sumoylation
|
Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of SUMO groups to a protein.
|
CAPN3,
CTNNB1,
GNL3L,
HMG20B
|
GO:0033235
|
BP
|
positive regulation of protein sumoylation
|
Any process that activates or increases the frequency, rate or extent of the addition of SUMO groups to a protein.
|
ARNT,
HDAC4,
RASD2,
GNL3,
TOLLIP
|
GO:0033260
|
BP
|
nuclear DNA replication
|
The DNA-dependent DNA replication that occurs in the nucleus of eukaryotic organisms as part of the cell cycle.
|
SLBP,
DONSON
|
GO:0033262
|
BP
|
regulation of nuclear cell cycle DNA replication
|
Any process that modulates the frequency, rate or extent of The DNA-dependent DNA replication that occurs in the nucleus of eukaryotic organisms as part of the cell cycle.
|
TIPIN,
CDT1,
DACH1
|
GO:0033273
|
BP
|
response to vitamin
|
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin stimulus.
|
PEMT
|
GO:0033274
|
BP
|
response to vitamin B2
|
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B2 stimulus.
|
MTHFR
|
GO:0033275
|
BP
|
actin-myosin filament sliding
|
The sliding movement of actin thin filaments and myosin thick filaments past each other.
|
ACTC1
|
GO:0033277
|
BP
|
abortive mitotic cell cycle
|
A cell cycle in which mitosis is begun and progresses normally through the end of anaphase, but not completed, resulting in a cell with increased ploidy.
|
PTPN11
|
GO:0033278
|
BP
|
cell proliferation in midbrain
|
The multiplication or reproduction of cells, resulting in the expansion of a cell population in the midbrain.
|
FZD6,
WNT2
|
GO:0033280
|
BP
|
response to vitamin D
|
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin D stimulus.
|
CYP27B1,
STC2,
TGFB1,
PTH,
CD4,
BGLAP,
ALPL,
SPP1,
TYR,
PTGS2,
STC1,
TRIM25,
TPCN2,
AQP3
|
GO:0033292
|
BP
|
T-tubule organization
|
A process that is carried out at the cellular level that results in the assembly, arrangement of constituent parts, or disassembly of the T-tubule. A T-tubule is an invagination of the plasma membrane of a muscle cell that extends inward from the cell surface around each myofibril.
|
ATP2A2,
ANK2
|
GO:0033299
|
BP
|
secretion of lysosomal enzymes
|
The controlled release of lysosomal enzymes by a cell.
|
GNPTAB,
NAGPA,
BLOC1S6
|
GO:0033301
|
BP
|
cell cycle comprising mitosis without cytokinesis
|
A mitotic cell cycle in which mitosis is completed but cytokinesis does not occur, resulting in a cell containing multiple nuclei each with a chromosomal complement of the original ploidy (usually 2N).
|
E2F8
|
GO:0033306
|
BP
|
phytol metabolic process
|
The chemical reactions and pathways involving phytol, (2E,7R,11R)-3,7,11,15-tetramethylhexadec-2-en-1-ol.
|
ALDH3A2
|
GO:0033313
|
BP
|
meiotic cell cycle checkpoint
|
A cell cycle checkpoint that ensures accurate chromosome replication and segregation by preventing progression through a meiotic cell cycle until conditions are suitable for the cell to proceed to the next stage.
|
NSUN2
|
GO:0033314
|
BP
|
mitotic DNA replication checkpoint
|
A cell cycle checkpoint that acts during a mitotic cell cycle and prevents the initiation of mitosis until DNA replication is complete, thereby ensuring that progeny inherit a full complement of the genome.
|
NAE1,
TOPBP1,
SLF1
|
GO:0033320
|
BP
|
UDP-D-xylose biosynthetic process
|
The chemical reactions and pathways resulting in the formation of UDP-D-xylose, uridinediphosphoxylose, a substance composed of xylose in glycosidic linkage with uridine diphosphate.
|
UXS1
|
GO:0033327
|
BP
|
Leydig cell differentiation
|
The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a Leydig cell. A Leydig cell is a testosterone-secreting cell in the interstitial area, between the seminiferous tubules, in the testis.
|
DHH,
AR,
MGST1,
NKX2-1,
NR0B1,
TMF1
|
GO:0033343
|
BP
|
positive regulation of collagen binding
|
Any process that activates or increases the frequency, rate or extent of collagen binding.
|
ITGA2
|
GO:0033344
|
BP
|
cholesterol efflux
|
The directed movement of cholesterol, cholest-5-en-3-beta-ol, out of a cell or organelle.
|
NPC1,
ABCA1,
APOA1,
APOE,
APOA2,
APOC1,
APOC3,
APOB,
SOAT1,
NPC2,
APOA5,
SCARB1,
ABCA5,
ABCG8
|
GO:0033345
|
BP
|
asparagine catabolic process via L-aspartate
|
The chemical reactions and pathways resulting in the breakdown of glutamate, via the intermediate L-aspartate.
|
ASRGL1
|
GO:0033353
|
BP
|
S-adenosylmethionine cycle
|
A cyclic series of interconversions involving S-adenosylmethionine, S-adenosyl-L-homocysteine, L-cysteine, and L-methionine. Couples utilization of the methyl group of SAM with recycling of the homocysteinyl group and regeneration of methionine.
|
AHCYL1,
AHCY
|
GO:0033363
|
BP
|
secretory granule organization
|
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a secretory granule. A secretory granule is a small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion.
|
SERPINE2,
CREB1
|
GO:0033364
|
BP
|
mast cell secretory granule organization
|
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a secretory granule in a mast cell. A secretory granule is a small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion.
|
SRGN,
LYST
|
GO:0033365
|
BP
|
protein localization to organelle
|
A process in which a protein is transported to, or maintained in, a location within an organelle.
|
AP3D1,
ANK2,
CROCC,
BICD1,
BBS2
|
GO:0033368
|
BP
|
protease localization to mast cell secretory granule
|
Any process in which a protease is transported to, or maintained in, a location within a secretory granule in a mast cell.
|
SRGN
|
GO:0033371
|
BP
|
T cell secretory granule organization
|
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a secretory granule in a T cell. A secretory granule is a small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion.
|
SRGN
|
GO:0033373
|
BP
|
maintenance of protease location in mast cell secretory granule
|
A process in which a protease is maintained in a secretory granule in a mast cell and prevented from moving elsewhere.
|
SRGN
|
GO:0033382
|
BP
|
maintenance of granzyme B location in T cell secretory granule
|
A process in which the protease granyme B is maintained in a secretory granule in a T cell and prevented from moving elsewhere.
|
SRGN
|
GO:0033384
|
BP
|
geranyl diphosphate biosynthetic process
|
The chemical reactions and pathways resulting in the formation of geranyl diphosphate.
|
FDPS
|
GO:0033387
|
BP
|
putrescine biosynthetic process from ornithine
|
The chemical reactions and pathways resulting in the formation of putrescine, 1,4-diaminobutane by decarboxylation of ornithine.
|
AZIN1,
ODC1
|
GO:0033388
|
BP
|
putrescine biosynthetic process from arginine
|
The chemical reactions and pathways resulting in the formation of putrescine, 1,4-diaminobutane, from other compounds, including arginine.
|
AGMAT
|
GO:0033484
|
BP
|
nitric oxide homeostasis
|
A homeostatic process involved in the maintenance of an internal steady state of nitric oxide within an organism or cell.
|
CAV1
|
GO:0033488
|
BP
|
cholesterol biosynthetic process via 24,25-dihydrolanosterol
|
The chemical reactions and pathways resulting in the formation of cholesterol, cholest-5-en-3 beta-ol, via the intermediate 24,25-dihydrolanosterol.
|
CYP51A1
|
GO:0033489
|
BP
|
cholesterol biosynthetic process via desmosterol
|
The chemical reactions and pathways resulting in the formation of cholesterol, cholest-5-en-3 beta-ol, via the intermediate desmosterol.
|
SC5D,
EBP,
DHCR24,
DHCR7
|
GO:0033490
|
BP
|
cholesterol biosynthetic process via lathosterol
|
The chemical reactions and pathways resulting in the formation of cholesterol, cholest-5-en-3 beta-ol, via the intermediate lathosterol.
|
SC5D,
EBP,
DHCR24,
DHCR7
|
GO:0033504
|
BP
|
floor plate development
|
The progression of the floor plate over time from its initial formation until its mature state.
|
COBL,
STIL
|
GO:0033512
|
BP
|
L-lysine catabolic process to acetyl-CoA via saccharopine
|
The chemical reactions and pathways resulting in the breakdown of L-lysine into other compounds, including acetyl-CoA, via the intermediate saccharopine.
|
DLST,
AASS
|
GO:0033514
|
BP
|
L-lysine catabolic process to acetyl-CoA via L-pipecolate
|
The chemical reactions and pathways resulting in the breakdown of L-lysine into other compounds, including acetyl-CoA, via the intermediate L-pipecolate.
|
PIPOX
|
GO:0033522
|
BP
|
histone H2A ubiquitination
|
The modification of histone H2A by addition of one or more ubiquitin groups.
|
RNF8,
UBE2A,
UBE2B
|
GO:0033523
|
BP
|
histone H2B ubiquitination
|
The modification of histone H2B by addition of ubiquitin groups.
|
RNF8,
UBE2E1
|
GO:0033539
|
BP
|
fatty acid beta-oxidation using acyl-CoA dehydrogenase
|
A fatty acid beta-oxidation pathway in which the initial step of each oxidation cycle, which converts an acyl-CoA to a trans-2-enoyl-CoA, is catalyzed by acyl-CoA dehydrogenase; the electrons removed by oxidation pass through the respiratory chain to oxygen and leave H2O as the product. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and ends when only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively).
|
ACOX3,
ACADSB,
ACADVL,
ACOX1,
ETFDH,
ACOX2
|
GO:0033540
|
BP
|
fatty acid beta-oxidation using acyl-CoA oxidase
|
A fatty acid beta-oxidation pathway in which the initial step, which converts an acyl-CoA to a trans-2-enoyl-CoA, is catalyzed by acyl-CoA oxidase; the electrons removed by oxidation pass directly to oxygen and produce hydrogen peroxide, which is cleaved by peroxisomal catalases. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and ends when only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively).
|
NUDT19,
ACOT8,
ACOX3,
SCP2,
CRAT,
HSD17B4,
ACOX1,
ACOX2,
CROT
|
GO:0033552
|
BP
|
response to vitamin B3
|
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B3 stimulus.
|
CCL2
|
GO:0033555
|
BP
|
multicellular organismal response to stress
|
Any process that results in a change in state or activity of a multicellular organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
|
LGALS1,
ADCYAP1R1,
PTEN,
PPP3CA,
SEPN1
|
GO:0033564
|
BP
|
anterior/posterior axon guidance
|
The process in which the migration of an axon growth cone is directed to a specific target site along the anterior-posterior body axis in response to a combination of attractive and repulsive cues. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism.
|
UNC5C,
UNC5B
|
GO:0033566
|
BP
|
gamma-tubulin complex localization
|
Any process in which a gamma-tubulin complex is transported to, or maintained in, a specific location.
|
MZT1
|
GO:0033567
|
BP
|
DNA replication, Okazaki fragment processing
|
The DNA metabolic process, occurring during lagging strand synthesis, by which RNA primers are removed from Okazaki fragments, the resulting gaps filled by DNA polymerization, and the ends ligated to form a continuous strand.
|
DNA2
|
GO:0033572
|
BP
|
transferrin transport
|
The directed movement of transferrin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
ATP6V0E1,
ATP6V1G1,
ATP6V1G2,
TFRC,
TF,
ATP6V1B2,
ATP6V1C1,
SLC11A2,
ATP6V0D1,
TCIRG1,
RAB11B,
ATP6V1F,
ATP6V1C2,
ATP6V0A1,
ATP6V1H,
TFR2,
ATP6V1D
|
GO:0033574
|
BP
|
response to testosterone
|
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a testosterone stimulus.
|
MSTN,
GNRH1,
BGLAP,
EDN1,
GPI,
THBS1,
CDK4,
NME1,
PLN,
CAD,
CALR,
DUSP1,
TSPO,
SRD5A2,
NASP,
HSF1,
MTAP,
KCNJ11,
BAD
|
GO:0033578
|
BP
|
protein glycosylation in Golgi
|
The addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid in any compartment of the Golgi apparatus.
|
LMF1,
FUT8
|
GO:0033590
|
BP
|
response to cobalamin
|
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cobalamin (vitamin B12) stimulus.
|
EGFR,
RELA
|
GO:0033591
|
BP
|
response to L-ascorbic acid
|
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an L-ascorbic acid (vitamin C) stimulus.
|
GSTP1,
SPARC,
ITGA2
|
GO:0033594
|
BP
|
response to hydroxyisoflavone
|
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydroxyisoflavone stimulus.
|
EGFR,
BGLAP
|
GO:0033598
|
BP
|
mammary gland epithelial cell proliferation
|
The multiplication or reproduction of mammary gland epithelial cells, resulting in the expansion of a cell population. Mammary gland epithelial cells make up the covering of surfaces of the mammary gland. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk.
|
TNFSF11,
CEBPB,
MAPK1,
ID2,
BTRC
|
GO:0033599
|
BP
|
regulation of mammary gland epithelial cell proliferation
|
Any process that modulates the frequency, rate or extent of mammary gland epithelial cell proliferation.
|
GPX1,
BAX,
PYGO2
|
GO:0033600
|
BP
|
negative regulation of mammary gland epithelial cell proliferation
|
Any process that stops, prevents or reduces the rate or extent of mammary gland epithelial cell proliferation.
|
BRCA2,
PHB2
|
GO:0033601
|
BP
|
positive regulation of mammary gland epithelial cell proliferation
|
Any process that activates or increases the rate or extent of mammary gland epithelial cell proliferation.
|
IQGAP3,
KDM5B
|
GO:0033602
|
BP
|
negative regulation of dopamine secretion
|
Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of dopamine.
|
DRD2,
CNR1,
ABAT
|
GO:0033603
|
BP
|
positive regulation of dopamine secretion
|
Any process that activates or increases the frequency, rate or extent of the regulated release of dopamine.
|
CXCL12,
NPY2R,
PINK1
|
GO:0033615
|
BP
|
mitochondrial proton-transporting ATP synthase complex assembly
|
The aggregation, arrangement and bonding together of a proton-transporting ATP synthase in the mitochondrial inner membrane.
|
ATPAF1
|
GO:0033617
|
BP
|
mitochondrial respiratory chain complex IV assembly
|
The aggregation, arrangement and bonding together of a set of components to form respiratory chain complex IV (also known as cytochrome c oxidase) in the mitochondrial inner membrane.
|
PET100,
COX17,
COX19,
COX20,
COX14,
TIMM21,
COA4,
BCS1L,
COA3
|
GO:0033619
|
BP
|
membrane protein proteolysis
|
The proteolytic cleavage of a transmembrane protein leading to the release of its intracellular or ecto-domains.
|
CTSH,
TMPRSS6,
SPPL3,
SPPL2A,
HM13
|
GO:0033622
|
BP
|
integrin activation
|
The aggregation, arrangement and bonding together of an integrin, a heterodimeric adhesion receptor formed by the non-covalent association of particular alpha and beta subunits, that lead to the increased affinity of the integrin for its extracellular ligands.
|
ITGB1BP1,
FN1,
COL16A1
|
GO:0033623
|
BP
|
regulation of integrin activation
|
Any process that modulates the frequency, rate, or extent of integrin activation.
|
FARP2,
FBLIM1
|
GO:0033624
|
BP
|
negative regulation of integrin activation
|
Any process that stops, prevents, or reduces the frequency, rate, or extent of integrin activation.
|
PTGER4,
KIF14
|
GO:0033625
|
BP
|
positive regulation of integrin activation
|
Any process that activates or increases the frequency, rate, or extent of integrin activation.
|
PIEZO1
|
GO:0033626
|
BP
|
positive regulation of integrin activation by cell surface receptor linked signal transduction
|
Any series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell that lead to the increased affinity of an integrin, a heterodimeric adhesion receptor formed by the non-covalent association of particular alpha and beta subunits, for its extracellular ligands.
|
CDH17
|
GO:0033627
|
BP
|
cell adhesion mediated by integrin
|
The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via an integrin, a heterodimeric adhesion receptor formed by the non-covalent association of particular alpha and beta subunits.
|
VTN,
ITGB3,
ICAM1,
ITGB1,
ITGAV,
ITGA5,
ITGA2,
ITGA6,
FBN1,
ADAM17,
COL16A1,
ADAM9,
ITGA11
|
GO:0033628
|
BP
|
regulation of cell adhesion mediated by integrin
|
Any process that modulates the frequency, rate, or extent of cell adhesion mediated by integrin.
|
ITGB1BP1,
LPXN,
PLAU,
LYN,
EFNA1,
PIK3CG,
PTK2,
PTPN11
|
GO:0033629
|
BP
|
negative regulation of cell adhesion mediated by integrin
|
Any process that stops, prevents, or reduces the frequency, rate, or extent of cell adhesion mediated by integrin.
|
SNAI2,
SERPINE1,
MUC1,
PTPN11,
PDE3B,
CYP1B1
|
GO:0033630
|
BP
|
positive regulation of cell adhesion mediated by integrin
|
Any process that activates or increases the frequency, rate, or extent of cell adhesion mediated by integrin.
|
SYK,
RAC3,
TGFB2,
ADAM9,
IFT74,
CIB1
|
GO:0033631
|
BP
|
cell-cell adhesion mediated by integrin
|
The attachment of one cell to another cell via an integrin, a heterodimeric adhesion receptor formed by the non-covalent association of particular alpha and beta subunits.
|
ITGB1,
ITGA5,
ADAM9
|
GO:0033632
|
BP
|
regulation of cell-cell adhesion mediated by integrin
|
Any process that modulates the frequency, rate, or extent of cell-cell adhesion mediated by integrin.
|
ADA,
DPP4
|
GO:0033634
|
BP
|
positive regulation of cell-cell adhesion mediated by integrin
|
Any process that activates or increases the frequency, rate, or extent of cell-cell adhesion mediated by integrin.
|
CCL5,
PIEZO1
|
GO:0033668
|
BP
|
negative regulation by symbiont of host apoptotic process
|
Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of programmed cell death in the host, where programmed cell death proceeds by apoptosis. The host is defined as the larger of the organisms involved in a symbiotic interaction.
|
SERPINB9
|
GO:0033673
|
BP
|
negative regulation of kinase activity
|
Any process that stops, prevents, or reduces the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.
|
MSTN,
CSK,
CDKN1B,
CDKN1C,
AJUBA,
IRS2
|
GO:0033674
|
BP
|
positive regulation of kinase activity
|
Any process that activates or increases the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.
|
NBN,
MRE11A,
LMO4,
DSTYK,
PIFO,
GCN1,
RAD50
|
GO:0033683
|
BP
|
nucleotide-excision repair, DNA incision
|
A process that results in the endonucleolytic cleavage of the damaged strand of DNA. The incision occurs at the junction of single-stranded DNA and double-stranded DNA that is formed when the DNA duplex is unwound.
|
ERCC1,
PARP1,
UBC,
PCNA,
ERCC2,
XPA,
POLD1,
GTF2H1,
RPA3,
RFC4,
RFC2,
RFC5,
RFC3,
RBX1,
RPS27A,
UBA52,
CUL4A,
CUL4B,
GTF2H2,
POLD3,
CHD1L,
GTF2H4,
ERCC4,
POLD4,
POLK,
FAN1
|
GO:0033686
|
BP
|
positive regulation of luteinizing hormone secretion
|
Any process that activates or increases the frequency, rate or extent of the regulated release of luteinizing hormone.
|
LEP,
FOXL2,
SMAD4,
KISS1
|
GO:0033687
|
BP
|
osteoblast proliferation
|
The multiplication or reproduction of osteoblasts, resulting in the expansion of an osteoblast cell population. An osteoblast is a bone-forming cell which secretes an extracellular matrix. Hydroxyapatite crystals are then deposited into the matrix to form bone.
|
JUNB
|
GO:0033688
|
BP
|
regulation of osteoblast proliferation
|
Any process that modulates the frequency, rate or extent of osteoblast proliferation.
|
NPR3,
FGFR2,
RHOA
|
GO:0033689
|
BP
|
negative regulation of osteoblast proliferation
|
Any process that stops, prevents or reduces the rate or extent of osteoblast proliferation.
|
GREM1,
BCL2,
SMAD3,
SFRP1
|
GO:0033690
|
BP
|
positive regulation of osteoblast proliferation
|
Any process that activates or increases the rate or extent of osteoblast proliferation.
|
CYR61,
LRP5,
ITGAV,
BMP2,
SOX8,
CTHRC1,
HPSE
|
GO:0033692
|
BP
|
cellular polysaccharide biosynthetic process
|
The chemical reactions and pathways resulting in the formation of polysaccharides, polymers of many (typically more than 10) monosaccharide residues linked glycosidically, occurring at the level of an individual cell.
|
EXT1,
EXT2
|
GO:0033693
|
BP
|
neurofilament bundle assembly
|
The assembly of neurofilaments into bundles, in which the filaments are longitudinally oriented, with numerous crossbridges between them. Neurofilament bundles may be cross-linked to each other, to membrane-bounded organelles or other cytoskeletal structures such as microtubules.
|
NEFH
|
GO:0033700
|
BP
|
phospholipid efflux
|
The directed movement of a phospholipid out of a cell or organelle.
|
ABCA1,
APOA1,
APOE,
APOA2,
APOC1,
APOC3,
APOA5
|
GO:0033762
|
BP
|
response to glucagon
|
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucagon stimulus.
|
CYC1,
QDPR,
PFKFB1,
CREB1,
CCNA2,
SREBF1,
CRY1,
CDO1
|
GO:0033861
|
BP
|
negative regulation of NAD(P)H oxidase activity
|
Any process that stops or reduces the activity of the enzyme NAD(P)H oxidase.
|
INS
|
GO:0033864
|
BP
|
positive regulation of NAD(P)H oxidase activity
|
Any process that activates or increases the activity of the enzyme NAD(P)H oxidase.
|
AGT,
AGTR1,
RFK
|
GO:0033962
|
BP
|
cytoplasmic mRNA processing body assembly
|
The aggregation, arrangement and bonding together of proteins and RNA molecules to form a cytoplasmic mRNA processing body.
|
LSM3,
DYNC1H1,
LSM14A,
EDC3,
LIMD1,
CNOT7,
NOCT,
LSM4
|
GO:0033993
|
BP
|
response to lipid
|
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipid stimulus.
|
VPS4B,
CD36,
PPARG,
HRSP12
|
GO:0034047
|
BP
|
regulation of protein phosphatase type 2A activity
|
Any process that modulates the activity of the enzyme protein phosphatase type 2A.
|
ENSA,
PPP2R1A,
PPP2R1B,
HTT,
ARPP19,
IGBP1,
SET,
PPP2R3A,
PPP2R5C,
PPP2R5D,
PPP2R5A,
PPP2R5B,
PPP2R4,
ANKLE2,
PPME1
|
GO:0034048
|
BP
|
negative regulation of protein phosphatase type 2A activity
|
Any process that stops or reduces the activity of the enzyme protein phosphatase type 2A.
|
MASTL
|
GO:0034058
|
BP
|
endosomal vesicle fusion
|
The homotypic fusion of endocytic vesicles to form or add to an early endosome.
|
VPS8,
ANKFY1
|