GO ID |
Ontology |
GO Term |
Term Definition |
Proteins |
GO:0032873
|
BP
|
negative regulation of stress-activated MAPK cascade
|
Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the stress-activated MAPK cascade.
|
MYC,
GSTP1,
IGBP1,
FOXM1,
FOXO1,
PBK
|
GO:0032874
|
BP
|
positive regulation of stress-activated MAPK cascade
|
Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the stress-activated MAPK cascade.
|
MID1,
ARL6IP5,
HMGCR,
TGFB2,
MAPK8IP2,
PDCD10,
TAOK3,
TAOK2
|
GO:0032876
|
BP
|
negative regulation of DNA endoreduplication
|
Any process that stops, prevents, or reduces the frequency, rate or extent of DNA endoreduplication.
|
MRE11A,
SMC1A,
SMC3
|
GO:0032877
|
BP
|
positive regulation of DNA endoreduplication
|
Any process that activates or increases the frequency, rate or extent of DNA endoreduplication.
|
E2F8
|
GO:0032878
|
BP
|
regulation of establishment or maintenance of cell polarity
|
Any process that modulates the frequency, rate or extent of the specification, formation or maintenance of anisotropic intracellular organization or cell growth patterns.
|
TEK
|
GO:0032880
|
BP
|
regulation of protein localization
|
Any process that modulates the frequency, rate or extent of any process in which a protein is transported to, or maintained in, a specific location.
|
WASL,
STX6,
DNAJB6,
RSL1D1,
INS,
PRNP,
MAPK8,
RAB9A,
RACK1,
PICALM,
PTCH1,
CAMK1,
SEPT2,
MMD,
AAK1,
RABGAP1L,
BORA,
TRIM22,
CEP120,
TEX15,
CELSR3,
B9D1
|
GO:0032886
|
BP
|
regulation of microtubule-based process
|
Any process that modulates the frequency, rate or extent of any cellular process that depends upon or alters the microtubule cytoskeleton.
|
ERBB2,
APC,
GSK3B,
KLHL42,
MACF1
|
GO:0032897
|
BP
|
negative regulation of viral transcription
|
Any process that stops, prevents, or reduces the frequency, rate or extent of viral transcription.
|
TRIM13,
ZFP36,
IFITM3,
TRIM14,
TRIM62,
TRIM8
|
GO:0032900
|
BP
|
negative regulation of neurotrophin production
|
Any process that stops, prevents, or reduces the frequency, rate, or extent of production of a neurotrophin.
|
ADORA1
|
GO:0032902
|
BP
|
nerve growth factor production
|
The appearance of nerve growth factor (NGF) due to biosynthesis or secretion by cells in a neuron's target field, resulting in an increase in its intracellular or extracellular levels.
|
FURIN,
PCSK6
|
GO:0032909
|
BP
|
regulation of transforming growth factor beta2 production
|
Any process that modulates the frequency, rate, or extent of production of transforming growth factor-beta2.
|
TGFB2,
SMAD3,
SMAD4,
HIF1A
|
GO:0032911
|
BP
|
negative regulation of transforming growth factor beta1 production
|
Any process that stops, prevents, or reduces the frequency, rate, or extent of production of transforming growth factor-beta1.
|
FURIN,
GATA6
|
GO:0032912
|
BP
|
negative regulation of transforming growth factor beta2 production
|
Any process that stops, prevents, or reduces the frequency, rate, or extent of production of transforming growth factor-beta2.
|
GATA6
|
GO:0032913
|
BP
|
negative regulation of transforming growth factor beta3 production
|
Any process that stops, prevents, or reduces the frequency, rate, or extent of production of transforming growth factor-beta3.
|
CD24
|
GO:0032914
|
BP
|
positive regulation of transforming growth factor beta1 production
|
Any process that activates or increases the frequency, rate, or extent of production of transforming growth factor-beta1.
|
THBS1,
LUM,
FOXP3
|
GO:0032916
|
BP
|
positive regulation of transforming growth factor beta3 production
|
Any process that activates or increases the frequency, rate, or extent of production of transforming growth factor-beta3.
|
CREB1,
SMAD3
|
GO:0032918
|
BP
|
spermidine acetylation
|
The modification of spermidine by addition of acetyl groups.
|
SAT1,
SAT2
|
GO:0032919
|
BP
|
spermine acetylation
|
The modification of spermine by addition of acetyl groups.
|
SAT1,
SAT2
|
GO:0032920
|
BP
|
putrescine acetylation
|
The modification of putrescine by addition of acetyl groups.
|
SAT1,
SAT2
|
GO:0032922
|
BP
|
circadian regulation of gene expression
|
Any process that modulates the frequency, rate or extent of gene expression such that an expression pattern recurs with a regularity of approximately 24 hours.
|
ARNTL,
BHLHE40,
OGT,
PER1,
USP2,
NGFR,
TOP1,
DRD2,
ATF4,
NR1D1,
KDM5A,
RORA,
AHR,
PPP1CC,
NAMPT,
NRIP1,
CSNK1D,
CSNK1E,
PPP1CA,
PPP1CB,
HNRNPU,
RELB,
ID2,
CREM,
GFPT1,
PPARA,
MTA1,
HDAC1,
NCOA2,
ZFHX3,
CRY1,
CARTPT,
HDAC2,
PRKCDBP,
NPAS2,
RBM4B,
MYBBP1A,
LGR4,
PPARGC1A,
NOCT
|
GO:0032924
|
BP
|
activin receptor signaling pathway
|
A series of molecular signals initiated by the binding of an extracellular ligand to an activin receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
|
BMP10,
INHBA,
INHBB,
ACVR2A,
ACVR1B,
TGFBR1,
SMAD3,
ACVR1,
ACVR2B,
BMPR2,
SMAD2
|
GO:0032925
|
BP
|
regulation of activin receptor signaling pathway
|
Any process that modulates the frequency, rate or extent of the activity of any activin receptor signaling pathway.
|
SMAD7
|
GO:0032926
|
BP
|
negative regulation of activin receptor signaling pathway
|
Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of any activin receptor signaling pathway.
|
SKI,
FST,
SYNJ2BP,
ACVR1,
MAGI2,
LEMD3
|
GO:0032927
|
BP
|
positive regulation of activin receptor signaling pathway
|
Any process that activates or increases the frequency, rate or extent of the activity of any activin receptor signaling pathway.
|
ACVR2A,
FGF9,
ACVR1B,
SYNJ2BP,
ACVR2B,
ZC3H3
|
GO:0032928
|
BP
|
regulation of superoxide anion generation
|
Any process that modulates the frequency, rate or extent of enzymatic generation of superoxide by a cell.
|
SYK
|
GO:0032929
|
BP
|
negative regulation of superoxide anion generation
|
Any process that stops, prevents, or reduces the frequency, rate or extent of enzymatic generation of superoxide by a cell.
|
AATF
|
GO:0032930
|
BP
|
positive regulation of superoxide anion generation
|
Any process that activates or increases the frequency, rate or extent of enzymatic generation of superoxide by a cell.
|
EGFR,
AGT,
TGFB1,
CRP,
GSTP1,
F2RL1,
PRKCD
|
GO:0032933
|
BP
|
SREBP signaling pathway
|
A series of molecular signals from the endoplasmic reticulum to the nucleus generated as a consequence of decreased levels of one or more sterols (and in some yeast, changes in oxygen levels) and which proceeds through activation of a sterol response element binding transcription factor (SREBP) to result in up-regulation of target gene transcription.
|
INSIG1,
ERLIN2
|
GO:0032940
|
BP
|
secretion by cell
|
The controlled release of a substance by a cell.
|
SERPINE2,
FURIN,
PCSK6,
TYRO3,
MERTK,
CKLF
|
GO:0032943
|
BP
|
mononuclear cell proliferation
|
The expansion of a mononuclear cell population by cell division. A mononuclear cell is a leukocyte with a single non-segmented nucleus in the mature form.
|
TGFB1,
ACE
|
GO:0032945
|
BP
|
negative regulation of mononuclear cell proliferation
|
Any process that stops, prevents, or reduces the frequency, rate or extent of mononuclear cell proliferation.
|
LILRB1
|
GO:0032946
|
BP
|
positive regulation of mononuclear cell proliferation
|
Any process that activates or increases the frequency, rate or extent of mononuclear cell proliferation.
|
IL12A
|
GO:0032956
|
BP
|
regulation of actin cytoskeleton organization
|
Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins.
|
ROCK2,
PDGFA,
PDGFRB,
RHOQ,
PAM,
EPHA3,
CORO1A,
EFNA5,
EPHA5,
RHOA,
TGFB2,
PRKCD,
BST2,
ARHGEF5,
ILK,
GPM6B,
DIXDC1,
FSCN1,
CCDC88A,
TWF2,
RICTOR,
ARHGAP18,
DLC1,
MLST8,
SH3BGRL3
|
GO:0032957
|
BP
|
inositol trisphosphate metabolic process
|
The chemical reactions and pathways involving myo-inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with three phosphate groups attached.
|
ITPK1
|
GO:0032958
|
BP
|
inositol phosphate biosynthetic process
|
The chemical reactions and pathways resulting in the formation of an inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with one or more phosphate groups attached.
|
FGF2,
PPIP5K1
|
GO:0032959
|
BP
|
inositol trisphosphate biosynthetic process
|
The chemical reactions and pathways resulting in the formation of inositol trisphosphate, 1,2,3,4,5,6-cyclohexanehexol, with three phosphate groups attached.
|
PLCG2,
PTAFR
|
GO:0032962
|
BP
|
positive regulation of inositol trisphosphate biosynthetic process
|
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of inositol trisphosphate.
|
LHCGR,
HRH1,
GPER1
|
GO:0032963
|
BP
|
collagen metabolic process
|
The chemical reactions and pathways involving collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%).
|
TNXB,
ID1,
HIF1A,
TNS2,
P3H2
|
GO:0032964
|
BP
|
collagen biosynthetic process
|
The chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%).
|
COL1A1,
COL5A1,
SERPINH1,
TRAM2
|
GO:0032966
|
BP
|
negative regulation of collagen biosynthetic process
|
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals.
|
IL6,
PPARG,
RAP1A,
PPARD,
CYGB,
ERRFI1
|
GO:0032967
|
BP
|
positive regulation of collagen biosynthetic process
|
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals.
|
F2,
TGFB1,
PDGFRB,
BMP4,
CCL2,
ITGA2,
F2R,
CTGF,
HDAC2,
RGCC
|
GO:0032968
|
BP
|
positive regulation of transcription elongation from RNA polymerase II promoter
|
Any process that activates or increases the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides, catalyzed by RNA polymerase II.
|
BRD4,
GTF2F2,
GTF2F1,
TCEB1,
SUPT6H,
RTF1
|
GO:0032970
|
BP
|
regulation of actin filament-based process
|
Any process that modulates the frequency, rate or extent of any cellular process that depends upon or alters the actin cytoskeleton.
|
FRMD6
|
GO:0032976
|
BP
|
release of matrix enzymes from mitochondria
|
The process in which enzymes, such as aspartate aminotransferase, are enabled to move from the mitochondrial matrix into the cytosol, as part of the apoptotic process.
|
BAX
|
GO:0032981
|
BP
|
mitochondrial respiratory chain complex I assembly
|
The aggregation, arrangement and bonding together of a set of components to form mitochondrial respiratory chain complex I.
|
NDUFS8,
NDUFAB1,
NDUFA1,
NDUFS4,
NDUFA2,
NDUFS2,
NDUFS6,
NDUFB6,
NDUFB4,
NDUFB8,
NDUFA7,
NDUFA10,
NDUFB10,
NDUFB7,
NDUFV2,
NDUFS1,
NDUFV3,
NDUFA5,
NDUFAF6,
NDUFAF5,
NDUFA11,
NDUFAF2,
NUBPL,
NDUFAF3,
TIMM21,
TIMMDC1,
NDUFB11,
NDUFAF4,
NDUFA13,
BCS1L
|
GO:0033003
|
BP
|
regulation of mast cell activation
|
Any process that modulates the frequency, rate, or extent of mast cell activation.
|
PLSCR1,
LYN
|
GO:0033004
|
BP
|
negative regulation of mast cell activation
|
Any process that stops, prevents, or reduces the frequency, rate, or extent of mast cell activation.
|
CNR1
|
GO:0033025
|
BP
|
regulation of mast cell apoptotic process
|
Any process that modulates the frequency, rate, or extent of mast cell apoptotic process.
|
ADAM17
|
GO:0033026
|
BP
|
negative regulation of mast cell apoptotic process
|
Any process that stops, prevents, or reduces the frequency, rate, or extent of mast cell apoptotic process.
|
KITLG
|
GO:0033030
|
BP
|
negative regulation of neutrophil apoptotic process
|
Any process that stops, prevents, or reduces the frequency, rate, or extent of neutrophil apoptotic process.
|
CXCR2
|
GO:0033031
|
BP
|
positive regulation of neutrophil apoptotic process
|
Any process that activates or increases the frequency, rate, or extent of neutrophil apoptotic process.
|
ANXA1
|
GO:0033032
|
BP
|
regulation of myeloid cell apoptotic process
|
Any process that modulates the frequency, rate, or extent of myeloid cell apoptotic process.
|
THRA,
PTEN
|
GO:0033033
|
BP
|
negative regulation of myeloid cell apoptotic process
|
Any process that stops, prevents, or reduces the frequency, rate, or extent of a myeloid cell apoptotic process.
|
APOH,
BCL2,
MIF,
MAEA
|
GO:0033034
|
BP
|
positive regulation of myeloid cell apoptotic process
|
Any process that activates or increases the frequency, rate, or extent of myeloid cell apoptotic process.
|
ADIPOQ
|
GO:0033037
|
BP
|
polysaccharide localization
|
Any process in which a polysaccharide is transported to, or maintained in, a specific location.
|
CHST11
|
GO:0033043
|
BP
|
regulation of organelle organization
|
Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle.
|
SEC22B,
CAMSAP2,
CAMSAP3
|
GO:0033044
|
BP
|
regulation of chromosome organization
|
Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a chromosome.
|
CENPV
|
GO:0033058
|
BP
|
directional locomotion
|
Self-propelled movement of a cell or organism from one location to another along an axis.
|
GRIN2A,
ARPIN
|
GO:0033059
|
BP
|
cellular pigmentation
|
The deposition or aggregation of coloring matter in a cell.
|
POMC
|
GO:0033076
|
BP
|
isoquinoline alkaloid metabolic process
|
The chemical reactions and pathways involving isoquinoline alkaloids, alkaloid compounds that contain bicyclic N-containing aromatic rings and are derived from a 3,4-dihydroxytyramine (dopamine) precursor that undergoes a Schiff base addition with aldehydes of different origin.
|
TH,
CYP2D6
|
GO:0033077
|
BP
|
T cell differentiation in thymus
|
The process in which a precursor cell type acquires the specialized features of a T cell via a differentiation pathway dependent upon transit through the thymus.
|
FZD7,
GLI3,
BCL2,
RAG1,
CTNNB1,
ZFP36L2,
STAT5B,
B2M,
RPS6,
PRKDC,
ADAM17,
CDK6,
ZFP36L1,
FADD,
JMJD6,
NKAP,
FZD8,
MAFB
|
GO:0033081
|
BP
|
regulation of T cell differentiation in thymus
|
Any process that modulates the frequency, rate or extent of T cell differentiation in the thymus.
|
CLPTM1,
ZEB1,
SOS1
|
GO:0033085
|
BP
|
negative regulation of T cell differentiation in thymus
|
Any process that stops, prevents, or reduces the frequency, rate or extent of T cell differentiation in the thymus.
|
BMP4
|
GO:0033087
|
BP
|
negative regulation of immature T cell proliferation
|
Any process that stops, prevents, or reduces the frequency, rate or extent of immature T cell proliferation.
|
GNRH1
|
GO:0033088
|
BP
|
negative regulation of immature T cell proliferation in thymus
|
Any process that stops, prevents, or reduces the frequency, rate or extent of immature T cell proliferation in the thymus.
|
KIAA0922,
ERBB2,
BMP4
|
GO:0033089
|
BP
|
positive regulation of T cell differentiation in thymus
|
Any process that activates or increases the frequency, rate or extent of T cell differentiation in the thymus.
|
VNN1,
ADA,
GLI2,
IL7R,
ADAM8,
EGR3
|
GO:0033091
|
BP
|
positive regulation of immature T cell proliferation
|
Any process that activates or increases the frequency, rate or extent of immature T cell proliferation.
|
RIPK2
|
GO:0033092
|
BP
|
positive regulation of immature T cell proliferation in thymus
|
Any process that activates or increases the frequency, rate or extent of immature T cell proliferation in the thymus.
|
FOXP3
|
GO:0033108
|
BP
|
mitochondrial respiratory chain complex assembly
|
The aggregation, arrangement and bonding together of a set of components to form a mitochondrial respiratory chain complex.
|
TFAM,
SAMM50
|
GO:0033119
|
BP
|
negative regulation of RNA splicing
|
Any process that stops, prevents, or reduces the frequency, rate or extent of RNA splicing.
|
PTBP3,
PTBP1,
RPS13,
RPS26,
PTBP2
|
GO:0033120
|
BP
|
positive regulation of RNA splicing
|
Any process that activates or increases the frequency, rate or extent of RNA splicing.
|
ZPR1,
ERN1,
POLR2A,
PIK3R1,
SRSF1,
SRSF5,
SETX,
RBM22
|
GO:0033128
|
BP
|
negative regulation of histone phosphorylation
|
Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of one or more phosphate groups to a histone protein.
|
H2AFY,
UBE2B,
TWIST1
|
GO:0033129
|
BP
|
positive regulation of histone phosphorylation
|
Any process that activates or increases the frequency, rate or extent of the addition of one or more phosphate groups to a histone protein.
|
RPS6KA5,
IL1B,
CCNB1,
MAPK3,
FMR1
|
GO:0033132
|
BP
|
negative regulation of glucokinase activity
|
Any process that stops, prevents, or reduces the frequency, rate or extent of glucokinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a glucose molecule.
|
PARK2,
RANBP2,
MIDN,
COX11
|
GO:0033133
|
BP
|
positive regulation of glucokinase activity
|
Any process that activates or increases the frequency, rate or extent of glucokinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a glucose molecule.
|
PFKFB2,
PFKFB1,
BAD
|
GO:0033135
|
BP
|
regulation of peptidyl-serine phosphorylation
|
Any process that modulates the frequency, rate or extent of the phosphorylation of peptidyl-serine.
|
PLCL1,
RICTOR,
SPTBN4,
PLCL2
|
GO:0033136
|
BP
|
serine phosphorylation of STAT3 protein
|
The process of introducing a phosphate group to a serine residue of the STAT3 protein.
|
CDK5,
NLK
|
GO:0033137
|
BP
|
negative regulation of peptidyl-serine phosphorylation
|
Any process that stops, prevents, or reduces the frequency, rate or extent of the phosphorylation of peptidyl-serine.
|
SMAD7,
DKK1,
DMD,
HGF,
PPM1F,
RACK1,
CAV1,
BAX,
PDE4D,
CNKSR3,
INPP5K,
DDIT4
|
GO:0033138
|
BP
|
positive regulation of peptidyl-serine phosphorylation
|
Any process that activates or increases the frequency, rate or extent of the phosphorylation of peptidyl-serine.
|
HAX1,
AXIN1,
RIPK2,
SPRY2,
CREBL2,
PPP1R15A,
BCAR3,
LATS1,
TGFB1,
GCG,
TNF,
RAF1,
IL6,
BCL2,
TXN,
MIF,
HCLS1,
LIF,
VEGFA,
CD44,
IL11,
ATP2B4,
AKT1,
SNCA,
WNT5A,
PIK3CA,
GSK3B,
CDC42,
CAV1,
STK4,
CAMK1,
GAS6,
PRKD1,
ANGPT1,
NTRK2,
FNIP1,
DOCK7,
PDCD10,
PINK1,
PRKD2,
TRIM6,
SMYD3,
FNIP2,
TBK1
|
GO:0033141
|
BP
|
positive regulation of peptidyl-serine phosphorylation of STAT protein
|
Any process that activates or increases the frequency, rate or extent of the phosphorylation of a serine residue of a STAT (Signal Transducer and Activator of Transcription) protein.
|
IFNA1 ,
IFNA16,
LIF,
IFNE
|
GO:0033144
|
BP
|
negative regulation of intracellular steroid hormone receptor signaling pathway
|
Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of any intracellular steroid hormone receptor signaling pathway.
|
CALR,
NR0B1
|
GO:0033146
|
BP
|
regulation of intracellular estrogen receptor signaling pathway
|
Any process that modulates the frequency, rate or extent of the activity of an intracellular estrogen receptor signaling pathway.
|
UFM1,
CARM1,
UBA5,
UFSP2
|
GO:0033147
|
BP
|
negative regulation of intracellular estrogen receptor signaling pathway
|
Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of an intracellular estrogen receptor signaling pathway.
|
CNOT1,
BRCA1,
STRN3,
KANK2,
CRIPAK,
PHB2
|
GO:0033148
|
BP
|
positive regulation of intracellular estrogen receptor signaling pathway
|
Any process that activates or increases the frequency, rate or extent of the activity of an intracellular estrogen receptor signaling pathway.
|
PARP1,
AR,
DDX5,
SKP2,
DDX17,
PAGR1
|
GO:0033151
|
BP
|
V(D)J recombination
|
The process in which immune receptor V, D, and J, or V and J gene segments, depending on the specific receptor, are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS).
|
HMGB1,
RAG1,
HMGB2,
DCLRE1C
|
GO:0033152
|
BP
|
immunoglobulin V(D)J recombination
|
The process in which immunoglobulin gene segments are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS). For immunoglobulin heavy chains V, D, and J gene segments are joined, and for immunoglobulin light chains V and J gene segments are joined.
|
TCF3,
PRKDC
|
GO:0033153
|
BP
|
T cell receptor V(D)J recombination
|
The process in which T cell receptor V, D, and J, or V and J gene segments, depending on the specific locus, are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS).
|
PRKDC
|
GO:0033157
|
BP
|
regulation of intracellular protein transport
|
Any process that modulates the frequency, rate or extent of the directed movement of proteins within cells.
|
LCP1,
SH3TC2,
NDEL1,
ATP13A2
|
GO:0033158
|
BP
|
regulation of protein import into nucleus, translocation
|
Any process that modulates the vectorial transfer of a protein from the cytoplasm into the nucleus, across the nuclear membrane.
|
TXN,
CDKN1A
|
GO:0033159
|
BP
|
negative regulation of protein import into nucleus, translocation
|
Any process that stops, prevents or reduces the vectorial transfer of a protein from the cytoplasm into the nucleus, across the nuclear membrane.
|
GAS6
|
GO:0033160
|
BP
|
positive regulation of protein import into nucleus, translocation
|
Any process that activates or increases the vectorial transfer of a protein from the cytoplasm into the nucleus, across the nuclear membrane.
|
JAK2,
UBR5,
IGF1,
IL6,
CDK1,
HSP90AA1,
HSP90AB1,
MAVS
|
GO:0033168
|
BP
|
conversion of ds siRNA to ss siRNA involved in RNA interference
|
The process in which double-stranded siRNA molecules are converted to single-stranded siRNAs; required for the formation of a mature RITS complex during RNA interference.
|
DICER1
|
GO:0033169
|
BP
|
histone H3-K9 demethylation
|
The modification of histone H3 by the removal of a methyl group from lysine at position 9 of the histone.
|
KDM1A,
JMJD1C,
KDM7A
|
GO:0033173
|
BP
|
calcineurin-NFAT signaling cascade
|
Any intracellular signal transduction in which the signal is passed on within the cell by activation of a member of the NFAT protein family as a consequence of NFAT dephosphorylation by Ca(2+)-activated calcineurin. The cascade begins with calcium-dependent activation of the phosphatase calcineurin. Calcineurin dephosphorylates multiple phosphoserine residues on NFAT, resulting in the translocation of NFAT to the nucleus. The cascade ends with regulation of transcription by NFAT. The calcineurin-NFAT cascade lies downstream of many cell surface receptors, including G-protein coupled receptors (GPCRs) and receptor tyrosine kinases (RTKs) that signal to mobilize calcium ions (Ca2+).
|
NFATC1,
RCAN1,
PPP3CA,
NFATC2,
NFATC4
|
GO:0033184
|
BP
|
positive regulation of histone ubiquitination
|
Any process that activates or increases the frequency, rate or extent of the addition of a ubiquitin group to a histone protein.
|
KDM1A
|
GO:0033189
|
BP
|
response to vitamin A
|
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin A stimulus.
|
ALDH1A2,
CYP1A1,
TYMS,
PPARG,
GATA4,
HAMP,
PPARD,
PITX2,
DNMT3B
|
GO:0033194
|
BP
|
response to hydroperoxide
|
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydroperoxide stimulus. Hydroperoxides are monosubstitution products of hydrogen peroxide, HOOH.
|
JAK2,
GPX1,
STX2,
STX4
|
GO:0033197
|
BP
|
response to vitamin E
|
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin E stimulus.
|
ADA,
ALAD,
LEP,
SRSF2,
HMGCS1,
MEF2C
|
GO:0033198
|
BP
|
response to ATP
|
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ATP (adenosine 5'-triphosphate) stimulus.
|
IL1B,
HSPD1,
SELL,
CASP1,
PTEN,
TRPC3,
KCNJ11,
PANX1,
P2RX4
|
GO:0033206
|
BP
|
meiotic cytokinesis
|
A cell cycle process that results in the division of the cytoplasm of a cell after meiosis, resulting in the separation of the original cell into two daughter cells.
|
ACTR3,
ACTR2
|