GO ID |
Ontology |
GO Term |
Term Definition |
Proteins |
GO:0031642
|
BP
|
negative regulation of myelination
|
Any process that stops, prevents, or reduces the frequency, rate or extent of the formation of a myelin sheath around nerve axons.
|
TNFRSF21,
PTEN,
MTMR2
|
GO:0031643
|
BP
|
positive regulation of myelination
|
Any process that activates or increases the frequency, rate or extent of the formation of a myelin sheath around nerve axons.
|
HGF,
MAG,
NRG1,
TENM4,
PARD3,
DICER1,
MYRF
|
GO:0031644
|
BP
|
regulation of neurological system process
|
Any process that modulates the frequency, rate or extent of a neurophysiological process, an organ system process carried out by any of the organs or tissues of neurological system.
|
HTR2C
|
GO:0031645
|
BP
|
negative regulation of neurological system process
|
Any process that stops, prevents, or reduces the frequency, rate or extent of a neurophysiological process.
|
NPY2R
|
GO:0031647
|
BP
|
regulation of protein stability
|
Any process that affects the structure and integrity of a protein, altering the likelihood of its degradation or aggregation.
|
AURKA,
HDAC3,
TADA3,
KRAS,
APOA2,
TF,
BCL2,
LAMP2,
MAPK1,
NF2,
SREBF1,
LSS,
NLRP5,
CD81,
PTEN,
CDC42,
ANK2,
SOX4,
PRKD1,
CCAR2,
RNF149,
RNF128,
LRRC46,
VPS35,
USP28,
HDAC8,
QRSL1,
GNL3L,
CDKN2AIP,
DACT1,
TOMM7,
DPM3,
HDAC6,
PYCARD,
STUB1,
SUGT1,
SH3GLB1
|
GO:0031648
|
BP
|
protein destabilization
|
Any process that decreases the stability of a protein, making it more vulnerable to degradative processes or aggregation.
|
PARK2,
CTSH,
BMP2,
XBP1,
SNCA,
ID1,
PLK1,
PRKDC,
MDM2,
SIAH1,
MYLIP,
NCLN,
SOX17,
BTRC
|
GO:0031649
|
BP
|
heat generation
|
Any homeostatic process in which an organism produces heat, thereby raising its internal temperature.
|
ADRB2,
ADRB1,
ADRB3
|
GO:0031651
|
BP
|
negative regulation of heat generation
|
Any process that stops, prevents, or reduces the rate or extent of heat generation.
|
ARRDC3
|
GO:0031652
|
BP
|
positive regulation of heat generation
|
Any process that activates or increases the rate or extent of heat generation.
|
ABAT,
SLC27A1,
APLN
|
GO:0031658
|
BP
|
negative regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle
|
Any process that stops, prevents, or reduces the frequency, rate or extent of cyclin-dependent protein serine/threonine kinase activity contributing to the G1/S transition of the cell cycle.
|
PTEN
|
GO:0031659
|
BP
|
positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle
|
Any process that activates or increases the frequency, rate or extent of cyclin-dependent protein serine/threonine kinase activity contributing to the G1/S transition of the cell cycle.
|
EGFR,
AKT1,
ADAM17,
PKD1,
PKD2,
RGCC
|
GO:0031663
|
BP
|
lipopolysaccharide-mediated signaling pathway
|
A series of molecular signals initiated by the binding of a lipopolysaccharide (LPS) to a receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription. Lipopolysaccharides are major components of the outer membrane of Gram-negative bacteria, making them prime targets for recognition by the immune system.
|
TLR4,
IRAK2,
RIPK2,
TLR2,
TGFB1,
TNF,
IL1B,
LYN,
CD14,
CCL3,
CCL2,
CCL5,
PTAFR,
MAPK3,
MAPK1,
NOS3,
CD6,
AKT1,
IRAK1,
IL18,
MAPK14,
MTDH,
SCARB1,
PTPN22
|
GO:0031664
|
BP
|
regulation of lipopolysaccharide-mediated signaling pathway
|
Any process that modulates the frequency, rate or extent of signaling in response to detection of lipopolysaccharide.
|
CD55
|
GO:0031665
|
BP
|
negative regulation of lipopolysaccharide-mediated signaling pathway
|
Any process that stops, prevents, or reduces the frequency, rate or extent of signaling in response to detection of lipopolysaccharide.
|
SIGIRR,
TRIB1,
NFKBIL1
|
GO:0031666
|
BP
|
positive regulation of lipopolysaccharide-mediated signaling pathway
|
Any process that activates or increases the frequency, rate or extent of signaling in response to detection of lipopolysaccharide.
|
MIF,
PRKCA,
BMP6
|
GO:0031667
|
BP
|
response to nutrient levels
|
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of nutrients.
|
ACACB,
FOXO3,
MBD3,
CST3,
NTRK1,
TH,
PON1,
SRD5A2,
FOXO4,
SORD,
CHSY1,
TPH2,
PROX1
|
GO:0031668
|
BP
|
cellular response to extracellular stimulus
|
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an extracellular stimulus.
|
FOS,
LYN,
FOSL1,
ITGA6,
ADORA2B,
CDKN1A,
CDKN2B,
SLC1A2,
NR4A2,
AES
|
GO:0031669
|
BP
|
cellular response to nutrient levels
|
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of nutrients.
|
ULK1,
IL6,
ICAM1,
PRKAA2,
TXN2
|
GO:0031670
|
BP
|
cellular response to nutrient
|
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nutrient stimulus.
|
HMOX1,
XBP1,
CDKN2B
|
GO:0031848
|
BP
|
protection from non-homologous end joining at telomere
|
A process that prevents non-homologous end joining at telomere, thereby ensuring that telomeres do not fuse.
|
ACD,
DCLRE1C
|
GO:0031860
|
BP
|
telomeric 3' overhang formation
|
The formation of the single stranded telomeric 3' overhang, a conserved feature that ranges in length from 12 nt in budding yeast to approximately 500 nt in humans.
|
NBN,
MRE11A,
RAD50
|
GO:0031914
|
BP
|
negative regulation of synaptic plasticity
|
A process that decreases synaptic plasticity, the ability of synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers.
|
CDK5
|
GO:0031915
|
BP
|
positive regulation of synaptic plasticity
|
A process that increases synaptic plasticity, the ability of synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers.
|
PTGS2,
CDC20,
CPLX2
|
GO:0031929
|
BP
|
TOR signaling
|
A series of molecular signals mediated by TOR (Target of rapamycin) proteins, members of the phosphoinositide (PI) 3-kinase related kinase (PIKK) family that act as serine/threonine kinases in response to nutrient availability or growth factors.
|
RPS6,
EIF4EBP1,
EIF4EBP2,
CCDC88A,
LARP1,
RICTOR,
FLCN,
RHEBL1,
FNIP1
|
GO:0031936
|
BP
|
negative regulation of chromatin silencing
|
Any process that stops, prevents, or reduces the frequency, rate or extent of chromatin silencing.
|
HMGA1,
ATAD2,
ASF1A
|
GO:0031943
|
BP
|
regulation of glucocorticoid metabolic process
|
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving glucocorticoids.
|
GAL,
STUB1
|
GO:0031952
|
BP
|
regulation of protein autophosphorylation
|
Any process that modulates the frequency, rate or extent of addition of the phosphorylation by a protein of one or more of its own residues.
|
PPP2R5B
|
GO:0031953
|
BP
|
negative regulation of protein autophosphorylation
|
Any process that stops, prevents or decreases the rate of the phosphorylation by a protein of one or more of its own residues.
|
JUN,
ENPP1,
ADIPOQ,
CHP1,
IMPACT,
ERRFI1
|
GO:0031954
|
BP
|
positive regulation of protein autophosphorylation
|
Any process that activates or increases the frequency, rate or extent of the phosphorylation by a protein of one or more of its own residues.
|
NBN,
PDGFB,
INS,
PDGFA,
RAP2A,
VEGFA,
VEGFC,
MRE11A,
RAP2B,
CALM2,
NEK10,
RAD50,
PDGFD,
PDGFC
|
GO:0031959
|
BP
|
mineralocorticoid receptor signaling pathway
|
Any series of molecular signals generated as a consequence of a mineralocorticoid binding to its receptor.
|
JAK2,
GPER1
|
GO:0031960
|
BP
|
response to corticosteroid
|
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticosteroid hormone stimulus. A corticosteroid is a steroid hormone that is produced in the adrenal cortex. Corticosteroids are involved in a wide range of physiologic systems such as stress response, immune response and regulation of inflammation, carbohydrate metabolism, protein catabolism, blood electrolyte levels, and behavior. They include glucocorticoids and mineralocorticoids.
|
GNRH1,
COL1A1,
NOTCH1
|
GO:0031987
|
BP
|
locomotion involved in locomotory behavior
|
Self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement.
|
GPR37,
ADGRL3,
CLN6,
FZD4,
MYO5A
|
GO:0031990
|
BP
|
mRNA export from nucleus in response to heat stress
|
The directed movement of mRNA from the nucleus to the cytoplasm during a heat stimulus, a temperature stimulus above the optimal temperature for the organism; in particular, a process that enables an organism withstand exposure to temperatures that would otherwise lethally impair poly(A)+ mRNA-nucleus export.
|
POLR2D,
TPR
|
GO:0031998
|
BP
|
regulation of fatty acid beta-oxidation
|
Any process that modulates the frequency, rate or extent of fatty acid bbeta-oxidation.
|
LONP2
|
GO:0031999
|
BP
|
negative regulation of fatty acid beta-oxidation
|
Any process that stops, prevents, or reduces the frequency, rate or extent of fatty acid beta-oxidation.
|
ACACB,
CNR1,
AKT1,
PLIN5
|
GO:0032000
|
BP
|
positive regulation of fatty acid beta-oxidation
|
Any process that activates or increases the frequency, rate or extent of fatty acid beta-oxidation.
|
AKT2,
IRS1,
CPT1A,
PLIN5,
PPARA,
TWIST1,
IRS2
|
GO:0032006
|
BP
|
regulation of TOR signaling
|
Any process that modulates the frequency, rate or extent of TOR signaling.
|
GNA12,
GPAT3,
FLCN,
RFFL,
FAM83D,
RRAGC,
FBXO9
|
GO:0032007
|
BP
|
negative regulation of TOR signaling
|
Any process that stops, prevents, or reduces the frequency, rate or extent of TOR signaling.
|
ARNTL,
PDCD6,
EPM2A,
TSC2,
PRKAA2,
NPRL3,
MTM1,
HIF1A,
UBR1,
FLCN,
DEPTOR,
FNIP1,
TNFAIP8L1,
DDIT4,
SH3BP4
|
GO:0032008
|
BP
|
positive regulation of TOR signaling
|
Any process that activates or increases the frequency, rate or extent of TOR signaling.
|
HDAC3,
LEP,
SEC13,
GAS6,
RHEB,
LAMTOR1,
RICTOR,
SLC38A9,
FLCN,
SEH1L,
MLST8,
RRAGC,
RRAGD,
LAMTOR3,
LAMTOR2
|
GO:0032012
|
BP
|
regulation of ARF protein signal transduction
|
Any process that modulates the frequency, rate or extent of ARF protein signal transduction.
|
CYTH3,
ARFGEF3,
IQSEC1,
GBF1,
FBXO8,
PSD3,
ARFGEF2
|
GO:0032020
|
BP
|
ISG15-protein conjugation
|
The covalent addition to a protein of ISG15, a ubiquitin-like protein.
|
ISG15,
UBA7,
UBE2E1,
UBE2E2
|
GO:0032024
|
BP
|
positive regulation of insulin secretion
|
Any process that activates or increases the frequency, rate or extent of the regulated release of insulin.
|
JAK2,
PFKFB2,
RBP4,
GJA1,
TRH,
ABAT,
PPARD,
SOX4,
TARDBP,
NR0B2,
PCK2,
AACS,
SLC30A8,
MYRIP,
BAD,
GPER1,
CAPN10,
TCF7L2,
GHRL,
IRS2
|
GO:0032025
|
BP
|
response to cobalt ion
|
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cobalt ion stimulus.
|
ALAD,
ATF1,
CASP9,
CASP8
|
GO:0032026
|
BP
|
response to magnesium ion
|
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a magnesium ion stimulus.
|
TNFRSF11B,
ENTPD6,
THBS1,
CD14,
BMP6,
SNCA,
MDM2
|
GO:0032042
|
BP
|
mitochondrial DNA metabolic process
|
The chemical reactions and pathways involving mitochondrial DNA.
|
PARP1,
SESN2
|
GO:0032049
|
BP
|
cardiolipin biosynthetic process
|
The chemical reactions and pathways resulting in the formation of cardiolipin, 1,3-bis(3-phosphatidyl)glycerol.
|
PGS1,
SLC27A1,
PTPMT1,
CRLS1
|
GO:0032053
|
BP
|
ciliary basal body organization
|
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a ciliary basal body, a short cylindrical array of microtubules and associated proteins found at the base of a eukaryotic cilium (also called flagellum).
|
CROCC
|
GO:0032055
|
BP
|
negative regulation of translation in response to stress
|
Any process that stops, prevents or reduces the rate of translation as a result of a stimulus indicating the organism is under stress.
|
RBM4
|
GO:0032057
|
BP
|
negative regulation of translational initiation in response to stress
|
Any process that stops, prevents or reduces the rate of translation initiation as a result of a stimulus indicating the organism is under stress.
|
EIF2S1,
ATF4,
EIF2B5,
EIF2B3,
EIF2AK4,
EIF2B4
|
GO:0032058
|
BP
|
positive regulation of translational initiation in response to stress
|
Any process that activates or increases the frequency, rate or extent of translation initiation as a result of a stimulus indicating the organism is under stress.
|
PPP1R15A
|
GO:0032060
|
BP
|
bleb assembly
|
The assembly of a bleb, a cell extension caused by localized decoupling of the cytoskeleton from the plasma membrane and characterized by rapid formation, rounded shape, and scarcity of organelles within the protrusion. Plasma membrane blebbing occurs during apoptosis and other cellular processes, including cell locomotion, cell division, and as a result of physical or chemical stresses.
|
EMP1,
EMP2,
EMP3,
PMP22,
MYLK,
ANO6
|
GO:0032066
|
BP
|
nucleolus to nucleoplasm transport
|
The directed movement of substances from the nucleolus to the nucleoplasm.
|
TBRG1,
NOC2L
|
GO:0032071
|
BP
|
regulation of endodeoxyribonuclease activity
|
Any process that modulates the frequency, rate or extent of endodeoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid by creating internal breaks.
|
NPM1
|
GO:0032072
|
BP
|
regulation of restriction endodeoxyribonuclease activity
|
Any process that modulates the frequency, rate or extent of a restriction endodeoxyribonuclease activity, the catalysis of endonucleolytic cleavage of DNA in a site-specific manner, resulting in double-strand breaks.
|
HMGB1
|
GO:0032075
|
BP
|
positive regulation of nuclease activity
|
Any process that activates or increases the frequency, rate or extent of nuclease activity, the hydrolysis of ester linkages within nucleic acids.
|
HMGB2
|
GO:0032077
|
BP
|
positive regulation of deoxyribonuclease activity
|
Any process that activates or increases the frequency, rate or extent of deoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid.
|
PCNA
|
GO:0032079
|
BP
|
positive regulation of endodeoxyribonuclease activity
|
Any process that activates or increases the frequency, rate or extent of endodeoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid by creating internal breaks.
|
AKT1,
PRKCD
|
GO:0032088
|
BP
|
negative regulation of NF-kappaB transcription factor activity
|
Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of the transcription factor NF-kappaB.
|
IRAK2,
KLF4,
PSMD10,
TRIM37,
ANXA4,
TNFAIP3,
DAP,
IRAK1,
MAP2K5,
PTGIS,
CYP1B1,
COMMD6,
TAX1BP1,
NLRC5,
COMMD1,
SETD6,
ZNF675,
PELI1,
ITCH,
NR1H4,
CHP1,
FOXP3,
CYLD,
NFKBIL1,
PYCARD,
IRAK3
|
GO:0032091
|
BP
|
negative regulation of protein binding
|
Any process that stops, prevents, or reduces the frequency, rate or extent of protein binding.
|
ITGB1BP1,
AURKA,
KDM1A,
PEX14,
DKK1,
PDGFB,
SLPI,
RALB,
ACE,
LRPAP1,
MAPK8,
NES,
CSNK1E,
GSK3B,
PPP1CA,
DAB2,
CAV1,
PRKCD,
BAX,
PPARA,
AES,
GOLGA2,
TDG,
CAMK1,
NFATC4,
CARM1,
TEX14,
MITD1,
SORL1,
AURKB,
GNL3L,
DACT1,
STUB1
|
GO:0032092
|
BP
|
positive regulation of protein binding
|
Any process that activates or increases the frequency, rate or extent of protein binding.
|
KRIT1,
FLOT1,
GCG,
VTN,
HSP90AB1,
RALB,
BMP2,
BMP4,
ACE,
WNT5A,
GSK3B,
B2M,
PKD1,
CDK5,
CAV1,
EP300,
TIAM1,
STK4,
BAMBI,
ARHGEF7,
HFE,
SPPL3,
CTHRC1,
TRIB3,
HIPK2,
AKTIP,
TCF7L2,
DACT1,
PLK2,
AMFR,
PLXND1
|
GO:0032094
|
BP
|
response to food
|
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a food stimulus; food is anything which, when taken into the body, serves to nourish or build up the tissues or to supply body heat.
|
BCL10,
GHRH,
CYP1A1,
MPO,
G6PD,
AKT1,
G6PC,
CHRNA7,
SREBF1,
HSD11B2,
GHSR
|
GO:0032095
|
BP
|
regulation of response to food
|
Any process that modulates the frequency, rate or extent of a response to a food stimulus.
|
MT3,
GHRL
|
GO:0032098
|
BP
|
regulation of appetite
|
Any process which modulates appetite, the desire or physical craving for food.
|
SLC22A3,
POMC,
HTR2C
|
GO:0032099
|
BP
|
negative regulation of appetite
|
Any process that reduces appetite.
|
CCK,
LEP,
PPARA,
CARTPT,
SPX,
NENF
|
GO:0032100
|
BP
|
positive regulation of appetite
|
Any process that increases appetite.
|
GHSR,
GHRL
|
GO:0032119
|
BP
|
sequestering of zinc ion
|
The process of binding or confining zinc ions such that they are separated from other components of a biological system.
|
S100A8,
S100A9,
SLC30A8
|
GO:0032147
|
BP
|
activation of protein kinase activity
|
Any process that initiates the activity of an inactive protein kinase.
|
AXIN1,
PDGFB,
ITGB3,
RPLP1,
INSR,
DRD2,
VEGFA,
TGFBR2,
PIK3CA,
SLC11A1,
EMP2,
TGFB2,
PRKCD,
DLG1,
ACVR2B,
KIF14,
STK11,
DBF4B,
DUSP19,
FGF13,
STRADB,
WNK1,
RGCC,
ECT2,
GPRC5B,
TPX2,
CAB39
|
GO:0032148
|
BP
|
activation of protein kinase B activity
|
Any process that initiates the activity of the inactive enzyme protein kinase B.
|
ITGB1BP1,
PDGFB,
INS,
ANG,
IGF1,
INSR,
TXN,
ADRA2B,
MT3,
WNT5A,
NRG1,
IL18,
GAS6,
CCDC88A,
PINK1,
OSBPL8
|
GO:0032200
|
BP
|
telomere organization
|
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of telomeres, terminal regions of a linear chromosome that include the telomeric DNA repeats and associated proteins.
|
HIST1H4A,
HIST1H3D,
H3F3A
|
GO:0032202
|
BP
|
telomere assembly
|
A cellular process that results in the aggregation, arrangement and bonding together of a set of components to form a telomere at a non-telomeric double-stranded DNA end. A telomere is a terminal region of a linear chromosome that includes telomeric DNA repeats and associated proteins.
|
ACD,
POT1
|
GO:0032204
|
BP
|
regulation of telomere maintenance
|
Any process that modulates the frequency, rate or extent of a process that affects and monitors the activity of telomeric proteins and the length of telomeric DNA.
|
MYC,
HDAC8,
PIF1,
SMG5
|
GO:0032205
|
BP
|
negative regulation of telomere maintenance
|
Any process that stops, prevents, or reduces the frequency, rate or extent of a process that affects and monitors the activity of telomeric proteins and the length of telomeric DNA.
|
ERCC1,
ERCC4
|
GO:0032206
|
BP
|
positive regulation of telomere maintenance
|
Any process that activates or increases the frequency, rate or extent of a process that affects and monitors the activity of telomeric proteins and the length of telomeric DNA.
|
NBN,
ATRX,
MRE11A,
RAD50,
GNL3,
DHX36
|
GO:0032210
|
BP
|
regulation of telomere maintenance via telomerase
|
Any process that modulates the frequency, rate or extent of the addition of telomeric repeats by telomerase.
|
TNKS,
SMG5
|
GO:0032211
|
BP
|
negative regulation of telomere maintenance via telomerase
|
Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of telomeric repeats by telomerase.
|
HNRNPC,
HNRNPA1,
TERF1,
HNRNPU,
ACD,
PIF1,
GNL3L
|
GO:0032212
|
BP
|
positive regulation of telomere maintenance via telomerase
|
Any process that activates or increases the frequency, rate or extent of the addition of telomeric repeats by telomerase.
|
MAP2K7,
DKC1,
TNKS,
HNRNPA1,
TCP1,
MAPK3,
MAPK1,
CTNNB1,
CCT6A,
CCT3,
CCT8,
NEK2,
CCT2,
PRKCQ,
NEK7,
ACD,
AURKB,
CCT7,
TNKS2,
OBFC1,
POT1,
MAP3K4
|
GO:0032214
|
BP
|
negative regulation of telomere maintenance via semi-conservative replication
|
Any process that stops, prevents, or reduces the frequency, rate or extent of the semi-conservative replication of telomeric DNA.
|
TERF1
|
GO:0032218
|
BP
|
riboflavin transport
|
The directed movement of riboflavin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Riboflavin (vitamin B2) is a water-soluble B-complex vitamin, converted in the cell to FMN and FAD, cofactors required for the function of flavoproteins.
|
SLC52A3
|
GO:0032224
|
BP
|
positive regulation of synaptic transmission, cholinergic
|
Any process that activates, maintains or increases the frequency, rate or extent of cholinergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter acetylcholine.
|
LAMA2
|
GO:0032225
|
BP
|
regulation of synaptic transmission, dopaminergic
|
Any process that modulates the frequency, rate or extent of dopaminergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter dopamine.
|
CHRNA7,
PNKD
|
GO:0032226
|
BP
|
positive regulation of synaptic transmission, dopaminergic
|
Any process that activates, maintains or increases the frequency, rate or extent of dopaminergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter dopamine.
|
FLOT1,
PINK1
|
GO:0032227
|
BP
|
negative regulation of synaptic transmission, dopaminergic
|
Any process that stops, prevents, or reduces the frequency, rate or extent of dopaminergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter dopamine.
|
PTGS2
|
GO:0032228
|
BP
|
regulation of synaptic transmission, GABAergic
|
Any process that modulates the frequency, rate or extent of GABAergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter gamma-aminobutyric acid (GABA).
|
KRAS,
DRD2,
CNR1,
PTEN,
USP46,
PLCL1,
PLCL2,
NISCH
|
GO:0032229
|
BP
|
negative regulation of synaptic transmission, GABAergic
|
Any process that stops, prevents, or reduces the frequency, rate or extent of GABAergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter gamma-aminobutyric acid (GABA).
|
SLC6A1,
ADORA1,
STXBP1,
NPY5R
|
GO:0032230
|
BP
|
positive regulation of synaptic transmission, GABAergic
|
Any process that activates, maintains or increases the frequency, rate or extent of GABAergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter gamma-aminobutyric acid (GABA).
|
CA2,
OXTR,
ADRA1A,
NLGN1
|
GO:0032231
|
BP
|
regulation of actin filament bundle assembly
|
Any process that modulates the frequency, rate or extent of the assembly of actin filament bundles.
|
RDX
|
GO:0032232
|
BP
|
negative regulation of actin filament bundle assembly
|
Any process that stops, prevents, or reduces the frequency, rate or extent of the assembly of actin filament bundles.
|
PARK2,
PFN1
|
GO:0032233
|
BP
|
positive regulation of actin filament bundle assembly
|
Any process that activates or increases the frequency, rate or extent of the assembly of actin filament bundles.
|
PFN1,
ID1,
SYNPO2
|
GO:0032237
|
BP
|
activation of store-operated calcium channel activity
|
A process that initiates the activity of an inactive store-operated calcium channel.
|
PLCG2,
STIM2
|
GO:0032244
|
BP
|
positive regulation of nucleoside transport
|
Any process that activates or increases the frequency, rate or extent of the directed movement of a nucleoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
ADORA1
|
GO:0032252
|
BP
|
secretory granule localization
|
Any process in which a secretory granule is transported to, and/or maintained in, a specific location within the cell.
|
PIK3CG,
MYO5A
|
GO:0032259
|
BP
|
methylation
|
The process in which a methyl group is covalently attached to a molecule.
|
TYMS,
PNMT,
COMT,
GCSH,
AHCY,
MAT2A,
NNMT,
HNMT,
TPMT,
PRDM15,
GSTO1,
MTAP,
NDUFAF5,
TYW3,
METTL23,
SETD9,
MTR,
DPH5,
METTL17,
METTL8,
METTL7A,
AS3MT,
PRDM10,
METTL5,
FAM86C1,
COQ3,
MAT2B,
PEMT,
N6AMT1
|
GO:0032261
|
BP
|
purine nucleotide salvage
|
Any process which produces a purine nucleotide from derivatives of it, without de novo synthesis.
|
ADA
|
GO:0032264
|
BP
|
IMP salvage
|
Any process which produces inosine monophosphate from derivatives of it, without de novo synthesis.
|
AMPD3
|
GO:0032268
|
BP
|
regulation of cellular protein metabolic process
|
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a protein, occurring at the level of an individual cell.
|
PM20D2
|
GO:0032269
|
BP
|
negative regulation of cellular protein metabolic process
|
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving a protein, occurring at the level of an individual cell.
|
EDN1,
MIF,
NFKB1
|
GO:0032270
|
BP
|
positive regulation of cellular protein metabolic process
|
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a protein, occurring at the level of an individual cell.
|
KLF4,
AGT,
TGFB1,
INS,
INHBA,
AGTR1,
AKT1,
NR1H2,
NR1H3,
ADIPOQ,
UHRF1
|
GO:0032272
|
BP
|
negative regulation of protein polymerization
|
Any process that stops, prevents, or reduces the frequency, rate or extent of the process of creating protein polymers.
|
VDAC2
|
GO:0032273
|
BP
|
positive regulation of protein polymerization
|
Any process that activates or increases the frequency, rate or extent of the process of creating protein polymers.
|
TPPP
|
GO:0032275
|
BP
|
luteinizing hormone secretion
|
The regulated release of luteinizing hormone, a gonadotropic glycoprotein hormone secreted by the anterior pituitary.
|
TMF1
|