GO:0008543

BP

fibroblast growth factor receptor signaling pathway

The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands.

POLR2D, FLRT2, RBFOX2, FGF18, FGF19, FGF2, HNRNPA1, UBC, FGFR1, GTF2F2, POLR2E, FGF7, FGFR2, ANOS1, POLR2A, PTBP1, MAPK3, MAPK1, CTGF, POLR2B, FGF9, TIA1, HNRNPH1, GTF2F1, POLR2I, IQGAP1, HNRNPM, POLR2J, NDST1, POLR2K, FGF12, POLR2G, POLR2L, RPS27A, UBA52, GRB2, PTPN11, NCBP1, SETX, SPRED1, CEP57, SHCBP1, FRS2, ESRP2, FLRT3, FLRT1, KL

GO:0008544

BP

epidermis development

The process whose specific outcome is the progression of the epidermis over time, from its formation to the mature structure. The epidermis is the outer epithelial layer of an animal, it may be a single layer that produces an extracellular material (e.g. the cuticle of arthropods) or a complex stratified squamous epithelium, as in the case of many vertebrate species.

INSR, KRT16, STS, PTHLH, DSP, ATP2A2, FGF7, CTGF, S100A7, SPRR2B, KRT9, ALDH3A2, EMP1, ELF3, ATP2C1, FABP5, SATB1, BNC1, PLOD1, KRT17, PPARA, GAB1, UGCG, LAMA3, SPRR2G, GRHL1, SPRR3, COL17A1

GO:0008582

BP

regulation of synaptic growth at neuromuscular junction

Any process that modulates the frequency, rate or extent of synaptic growth at neuromuscular junctions.

MUSK, COLQ

GO:0008584

BP

male gonad development

The process whose specific outcome is the progression of the male gonad over time, from its formation to the mature structure.

TLR3, BCL2L11, SOX15, NUPR1, TLR5, LHB, ESR1, INHA, INSR, ERCC1, INHBA, BCL2, KIT, SRD5A1, WT1, KITLG, LHCGR, RRM1, FSHR, HMGB2, KDM5A, SRD5A2, HOXA10, FGF9, CTNNA1, NUDT1, TGFBR1, WNT5A, AKR1C3, MSH2, GATA4, SOX9, NASP, STAR, MMP14, TNFSF10, NR0B1, SOX8, TGFB2, H3F3A, HMGCS1, PRDX4, MAMLD1, NCOA4, ARID5B, NCOA1, AMHR2, ASPM, SFRP1, GATA6, WNT2B, PITX2, RNF38, PATZ1, AGO4, BOK

GO:0008585

BP

female gonad development

The process whose specific outcome is the progression of the female gonad over time, from its formation to the mature structure.

IDH1, FSHR, BRCA2, ARID5B, AMHR2, SFRP1, PITX2

GO:0008588

BP

release of cytoplasmic sequestered NF-kappaB

The release of NF-kappaB from specific molecules in the cytoplasm to which it was bound, thereby allowing its translocation into the nucleus.

CD27, TRIP6

GO:0008589

BP

regulation of smoothened signaling pathway

Any process that modulates the frequency, rate or extent of smoothened signaling.

GLI2, FGFR2, OTX2, RORA, GAS1, PTCH1, ZIC1, CREBBP, INTU

GO:0008593

BP

regulation of Notch signaling pathway

Any process that modulates the frequency, rate or extent of the Notch signaling pathway.

CD46, IL6ST, SYNJ2BP, POSTN

GO:0008595

BP

anterior/posterior axis specification, embryo

The specification of the anterior/posterior axis of the embryo by the products of genes expressed maternally and genes expressed in the zygote.

TDGF1, WNT5A, FRS2

GO:0008608

BP

attachment of spindle microtubules to kinetochore

The process in which spindle microtubules become physically associated with the proteins making up the kinetochore complex.

NDC80, ZNF207, BUB3, FAM175B, SGOL1, TEX14, CASC5, AURKB

GO:0008610

BP

lipid biosynthetic process

The chemical reactions and pathways resulting in the formation of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent.

AGPS, ACSL1, SREBF1, PRKAA2, GPAT4, ACSS2, PRPF19

GO:0008611

BP

ether lipid biosynthetic process

The chemical reactions and pathways resulting in the formation of ether lipids, lipids that contain (normally) one lipid alcohol in ether linkage to one of the carbon atoms (normally C-1) of glycerol.

AGPS, GNPAT

GO:0008612

BP

peptidyl-lysine modification to peptidyl-hypusine

The modification of peptidyl-lysine to form hypusine, peptidyl-N6-(4-amino-2-hydroxybutyl)-L-lysine.

DHPS, EIF5A, DOHH, EIF5A2

GO:0008615

BP

pyridoxine biosynthetic process

The chemical reactions and pathways resulting in the formation of pyridoxine, 2-methyl-3-hydroxy-4,5-bis(hydroxymethyl)pyridine, one of the vitamin B6 compounds.

PSAT1

GO:0008616

BP

queuosine biosynthetic process

The chemical reactions and pathways resulting in the formation of queuosines, any of a series of nucleosides found in tRNA and having an additional pentenyl ring added via an NH group to the methyl group of 7-methylguanosine. The pentenyl ring may carry other substituents.

PDC, PDCL, PDCL3

GO:0008617

BP

guanosine metabolic process

The chemical reactions and pathways involving guanine, guanine riboside, a nucleoside with a wide species distribution.

DGUOK

GO:0008625

BP

extrinsic apoptotic signaling pathway via death domain receptors

A series of molecular signals in which a signal is conveyed from the cell surface to trigger the apoptotic death of a cell. The pathway starts with a ligand binding to a death domain receptor on the cell surface, and ends when the execution phase of apoptosis is triggered.

DDX3X, TNFRSF10C, NGF, TNF, BCL2, FAS, CD27, PIK3R1, DAPK1, BID, CRADD, BAX, FADD, TRADD, BAD, MOAP1, DDX47

GO:0008626

BP

granzyme-mediated apoptotic signaling pathway

A series of molecular signals induced by granzymes which triggers the apoptotic death of a cell. The pathway starts with reception of a granzyme signal, and ends when the execution phase of apoptosis is triggered. Granzymes are serine proteases that are secreted by cytotoxic T cells and natural killer cells to induce apoptosis in target cells.

UBE4B, SRGN, LAMP1, BNIP3

GO:0008628

BP

hormone-mediated apoptotic signaling pathway

A series of molecular signals mediated by the detection of a hormone, and which triggers the apoptotic signaling pathway in a cell. The pathway starts with reception of a hormone signal, and ends when the execution phase of apoptosis is triggered.

PTH

GO:0008630

BP

intrinsic apoptotic signaling pathway in response to DNA damage

A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced by the detection of DNA damage, and ends when the execution phase of apoptosis is triggered.

BCL2L11, TNF, HMOX1, BCL2, TNFRSF1B, XPA, PIK3R1, SFN, BRCA1, MLH1, MSH6, CASP9, PRKDC, E2F1, BAX, MCL1, NFATC4, BCL2L2, BAD, MOAP1, FNIP2, BOK

GO:0008631

BP

intrinsic apoptotic signaling pathway in response to oxidative stress

A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced in response to oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, and ends when the execution phase of apoptosis is triggered.

PRODH, JAK2, ARL6IP5, GPX1, BCL2, PRKCD, MELK, PDK1, CYP1B1, MAP3K5, STK24

GO:0008635

BP

activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c

Any process that initiates the activity of the inactive enzyme cysteine-type endopeptidase in the context of an apoptotic process and is mediated by cytochrome c.

CASP9, CYCS, BAX

GO:0008637

BP

apoptotic mitochondrial changes

The morphological and physiological alterations undergone by mitochondria during apoptosis.

HSPD1, SLC25A4, NDUFS1, PPIF, AKT1, GCLC, GCLM, BID, PPP2CB, BAX, MCL1, AIFM2

GO:0008643

BP

carbohydrate transport

The directed movement of carbohydrate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carbohydrates are any of a group of organic compounds based of the general formula Cx(H2O)y.

AKT2, SLC35A1, PEA15, SLC35D2, SLC5A11, SLC35A5, SLC35D1, SLC35A3

GO:0008645

BP

hexose transport

The directed movement of hexose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Hexoses are any aldoses with a chain of six carbon atoms in the molecule.

SLC2A5

GO:0008652

BP

cellular amino acid biosynthetic process

The chemical reactions and pathways resulting in the formation of amino acids, organic acids containing one or more amino substituents.

GLS, GOT2, ASNS, CBS, ALDH18A1, PYCRL, GPT2

GO:0008654

BP

phospholipid biosynthetic process

The chemical reactions and pathways resulting in the formation of phospholipids, any lipid containing phosphoric acid as a mono- or diester.

FADS1, PTDSS1, PCYT1A, PLA2G16, PPARD, LPCAT3, MBOAT2, SERINC5, ABHD5, LPGAT1, MBOAT7, PCYT2, ISYNA1, SERINC1, AGPAT4, AGPAT3, PEMT, PCYT1B

GO:0009048

BP

dosage compensation by inactivation of X chromosome

Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global inactivation of all, or most of, the genes on one of the X-chromosomes in the XX sex.

BRCA1, EIF1

GO:0009051

BP

pentose-phosphate shunt, oxidative branch

The branch of the pentose-phosphate shunt which involves the oxidation of glucose 6-P and produces ribulose 5-P, reduced NADP+ and carbon dioxide (CO2).

G6PD, PGD

GO:0009052

BP

pentose-phosphate shunt, non-oxidative branch

The branch of the pentose-phosphate shunt which does not involve oxidation reactions. It comprises a series of sugar phosphate interconversions, starting with ribulose 5-P and producing fructose 6-P and glyceraldehyde 3-P.

TKT, TALDO1, SHPK

GO:0009056

BP

catabolic process

The chemical reactions and pathways resulting in the breakdown of substances, including the breakdown of carbon compounds with the liberation of energy for use by the cell or organism.

TMEM150A, PTER

GO:0009058

BP

biosynthetic process

The chemical reactions and pathways resulting in the formation of substances; typically the energy-requiring part of metabolism in which simpler substances are transformed into more complex ones.

ALDH1L1, PBLD, NDUFAF6, ALDH1L2, APMAP

GO:0009060

BP

aerobic respiration

The enzymatic release of energy from inorganic and organic compounds (especially carbohydrates and fats) which requires oxygen as the terminal electron acceptor.

PMPCB, SLC25A14, UQCRH, UQCRB, SDHB, UQCRC2, ADSL, UQCRC1, BLOC1S1, MTFR1, FXN, ME3, COX19, COX20, MTFR2, SDHC, CHCHD5, PANK2, METTL17, UQCR10, COX11

GO:0009062

BP

fatty acid catabolic process

The chemical reactions and pathways resulting in the breakdown of a fatty acid, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which may be saturated or unsaturated; branched fatty acids and hydroxy fatty acids also occur, and very long chain acids of over 30 carbons are found in waxes.

PPARD, ECH1, LPIN1

GO:0009063

BP

cellular amino acid catabolic process

The chemical reactions and pathways resulting in the breakdown of amino acids, organic acids containing one or more amino substituents.

ENOSF1

GO:0009069

BP

serine family amino acid metabolic process

The chemical reactions and pathways involving amino acids of the serine family, comprising cysteine, glycine, homoserine, selenocysteine and serine.

MTHFD1

GO:0009070

BP

serine family amino acid biosynthetic process

The chemical reactions and pathways resulting in the formation of amino acids of the serine family, comprising cysteine, glycine, homoserine, selenocysteine and serine.

PHGDH, MTHFD1

GO:0009071

BP

serine family amino acid catabolic process

The chemical reactions and pathways resulting in the breakdown of amino acids of the serine family, comprising cysteine, glycine, homoserine, selenocysteine and serine.

THNSL2

GO:0009072

BP

aromatic amino acid family metabolic process

The chemical reactions and pathways involving aromatic amino acid family, amino acids with aromatic ring (phenylalanine, tyrosine, tryptophan).

TPH2, HPDL

GO:0009082

BP

branched-chain amino acid biosynthetic process

The chemical reactions and pathways resulting in the formation of amino acids containing a branched carbon skeleton, comprising isoleucine, leucine and valine.

BCAT1

GO:0009083

BP

branched-chain amino acid catabolic process

The chemical reactions and pathways resulting in the breakdown of amino acids containing a branched carbon skeleton, comprising isoleucine, leucine and valine.

DLD, DBT, BCKDHA, BCKDHB, HIBADH, ACADSB, BCAT1, ALDH6A1, AUH, HIBCH, PPM1K, MCCC1, HSD17B10, MCCC2

GO:0009086

BP

methionine biosynthetic process

The chemical reactions and pathways resulting in the formation of methionine (2-amino-4-(methylthio)butanoic acid), a sulfur-containing, essential amino acid found in peptide linkage in proteins.

MTHFD1, MTR, MTHFD2L

GO:0009098

BP

leucine biosynthetic process

The chemical reactions and pathways resulting in the formation of leucine, 2-amino-4-methylpentanoic acid.

BCAT1

GO:0009099

BP

valine biosynthetic process

The chemical reactions and pathways resulting in the formation of valine, 2-amino-3-methylbutanoic acid.

BCAT1

GO:0009100

BP

glycoprotein metabolic process

The chemical reactions and pathways involving glycoproteins, any protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide.

PCSK6, ST8SIA6, ERP44

GO:0009101

BP

glycoprotein biosynthetic process

The chemical reactions and pathways resulting in the formation of glycoproteins, any protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide.

LARGE

GO:0009106

BP

lipoate metabolic process

The chemical reactions and pathways involving lipoate, 1,2-dithiolane-3-pentanoate, the anion derived from lipoic acid.

DLD

GO:0009108

BP

coenzyme biosynthetic process

The chemical reactions and pathways resulting in the formation of coenzymes, any of various nonprotein organic cofactors that are required, in addition to an enzyme and a substrate, for an enzymatic reaction to proceed.

SLC25A16, COASY, PANK2

GO:0009113

BP

purine nucleobase biosynthetic process

The chemical reactions and pathways resulting in the formation of purine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, which include adenine and guanine.

GART, PAICS, SHMT1, GMPS, PPAT

GO:0009115

BP

xanthine catabolic process

The chemical reactions and pathways resulting in the breakdown of xanthine, 2,6-dihydroxypurine, a purine formed in the metabolic breakdown of guanine but not present in nucleic acids.

XDH, AOX1

GO:0009116

BP

nucleoside metabolic process

The chemical reactions and pathways involving a nucleoside, a nucleobase linked to either beta-D-ribofuranose (a ribonucleoside) or 2-deoxy-beta-D-ribofuranose, (a deoxyribonucleoside), e.g. adenosine, guanosine, inosine, cytidine, uridine and deoxyadenosine, deoxyguanosine, deoxycytidine and thymidine (= deoxythymidine).

NME4, UPP2, PRPS2, PPAT

GO:0009117

BP

nucleotide metabolic process

The chemical reactions and pathways involving a nucleotide, a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the glycose moiety; may be mono-, di- or triphosphate; this definition includes cyclic nucleotides (nucleoside cyclic phosphates).

ACPP, FHIT, SMARCAD1, NUDT5, REXO2

GO:0009132

BP

nucleoside diphosphate metabolic process

The chemical reactions and pathways involving a nucleoside diphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with diphosphate on the sugar.

NUDT7

GO:0009134

BP

nucleoside diphosphate catabolic process

The chemical reactions and pathways resulting in the breakdown of a nucleoside diphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with diphosphate on the sugar.

ENTPD3

GO:0009142

BP

nucleoside triphosphate biosynthetic process

The chemical reactions and pathways resulting in the formation of a nucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with triphosphate on the sugar.

NME4, AK1, NME1, NME2, AK4, CMPK1, SUCLG1, CMPK2, AK8

GO:0009143

BP

nucleoside triphosphate catabolic process

The chemical reactions and pathways resulting in the breakdown of a nucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with triphosphate on the sugar.

ENPP3, ENTPD3, ENPP1, DCTPP1

GO:0009154

BP

purine ribonucleotide catabolic process

The chemical reactions and pathways resulting in the breakdown of a purine ribonucleotide, a compound consisting of ribonucleoside (a purine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.

HINT1

GO:0009156

BP

ribonucleoside monophosphate biosynthetic process

The chemical reactions and pathways resulting in the formation of a ribonucleoside monophosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with phosphate on the sugar.

PFAS, PRPS2

GO:0009157

BP

deoxyribonucleoside monophosphate biosynthetic process

The chemical reactions and pathways resulting in the formation of a deoxyribonucleoside monophosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with phosphate on the sugar.

TK2, TK1, TYMS, DCK, DGUOK

GO:0009165

BP

nucleotide biosynthetic process

The chemical reactions and pathways resulting in the formation of nucleotides, any nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the glycose moiety; may be mono-, di- or triphosphate; this definition includes cyclic-nucleotides (nucleoside cyclic phosphates).

TK2, DHFR, TK1, PRPS2, DCK, DCTD, DGUOK, AK8

GO:0009166

BP

nucleotide catabolic process

The chemical reactions and pathways resulting in the breakdown of nucleotides, any nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the glycose moiety; may be mono-, di- or triphosphate; this definition includes cyclic-nucleotides (nucleoside cyclic phosphates).

UPP2, UPP1

GO:0009168

BP

purine ribonucleoside monophosphate biosynthetic process

The chemical reactions and pathways resulting in the formation of purine ribonucleoside monophosphate, a compound consisting of a purine base linked to a ribose sugar esterified with phosphate on the sugar.

PFAS, ADA, GART, PAICS, ADSS, ADSL, GMPS, PPAT, ADSSL1

GO:0009186

BP

deoxyribonucleoside diphosphate metabolic process

The chemical reactions and pathways involving a deoxyribonucleoside diphosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with diphosphate on the sugar.

RRM2

GO:0009187

BP

cyclic nucleotide metabolic process

The chemical reactions and pathways involving a cyclic nucleotide, a nucleotide in which the phosphate group is in diester linkage to two positions on the sugar residue.

PDE8A, PDE8B

GO:0009191

BP

ribonucleoside diphosphate catabolic process

The chemical reactions and pathways resulting in the breakdown of a ribonucleoside diphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with diphosphate on the sugar.

NUDT5

GO:0009214

BP

cyclic nucleotide catabolic process

The chemical reactions and pathways resulting in the breakdown of a cyclic nucleotide, a nucleotide in which the phosphate group is in diester linkage to two positions on the sugar residue.

CNP

GO:0009220

BP

pyrimidine ribonucleotide biosynthetic process

The chemical reactions and pathways resulting in the formation of a pyrimidine ribonucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.

CMPK1

GO:0009223

BP

pyrimidine deoxyribonucleotide catabolic process

The chemical reactions and pathways resulting in the breakdown of a pyrimidine deoxyribonucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.

NT5C

GO:0009225

BP

nucleotide-sugar metabolic process

The cellular chemical reactions and pathways involving nucleotide-sugars, any nucleotide-carbohydrate in which the distal phosphoric residue of a nucleoside 5'-diphosphate is in glycosidic linkage with a monosaccharide or monosaccharide derivative.

TGDS

GO:0009229

BP

thiamine diphosphate biosynthetic process

The chemical reactions and pathways resulting in the formation of thiamine diphosphate, a derivative of thiamine (vitamin B1) which acts as a coenzyme in a range of processes including the Krebs cycle.

TPK1

GO:0009231

BP

riboflavin biosynthetic process

The chemical reactions and pathways resulting in the formation of riboflavin (vitamin B2), the precursor for the coenzymes flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD).

RFK

GO:0009235

BP

cobalamin metabolic process

The chemical reactions and pathways involving cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom.

ABCD4, PRSS1, ABCC1, PRSS3, CTRB2, MMAA, MMAB, MTR, CD320, LMBRD1

GO:0009236

BP

cobalamin biosynthetic process

The chemical reactions and pathways resulting in the formation of cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom.

MMAA, MMAB

GO:0009247

BP

glycolipid biosynthetic process

The chemical reactions and pathways resulting in the formation of glycolipid, a class of 1,2-di-O-acylglycerols joined at oxygen 3 by a glycosidic linkage to a carbohydrate part (usually a mono-, di- or tri-saccharide).

ST8SIA6, B3GNT5

GO:0009249

BP

protein lipoylation

The addition of a lipoyl group to an amino acid residue in a protein.

NDUFAB1, POP5, LIPT1

GO:0009253

BP

peptidoglycan catabolic process

The chemical reactions and pathways resulting in the breakdown of peptidoglycans, any of a class of glycoconjugates found in bacterial cell walls.

LYG2, PGLYRP2

GO:0009256

BP

10-formyltetrahydrofolate metabolic process

The chemical reactions and pathways involving 10-formyltetrahydrofolate, the formylated derivative of tetrahydrofolate.

MTHFD2L

GO:0009257

BP

10-formyltetrahydrofolate biosynthetic process

The chemical reactions and pathways resulting in the formation of 10-formyltetrahydrofolate, the formylated derivative of tetrahydrofolate.

MTHFD1

GO:0009258

BP

10-formyltetrahydrofolate catabolic process

The chemical reactions and pathways resulting in the breakdown of 10-formyltetrahydrofolate, the formylated derivative of tetrahydrofolate.

ALDH1L1, ALDH1L2

GO:0009259

BP

ribonucleotide metabolic process

The chemical reactions and pathways involving a ribonucleotide, a compound consisting of ribonucleoside (a base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.

RNASEH2B

GO:0009263

BP

deoxyribonucleotide biosynthetic process

The chemical reactions and pathways resulting in the formation of a deoxyribonucleotide, a compound consisting of deoxyribonucleoside (a base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.

RRM1, RRM2

GO:0009264

BP

deoxyribonucleotide catabolic process

The chemical reactions and pathways resulting in the breakdown of a deoxyribonucleotide, a compound consisting of deoxyribonucleoside (a base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.

DERA

GO:0009266

BP

response to temperature stimulus

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a temperature stimulus.

ERO1A, GLRX2, TRPV2

GO:0009267

BP

cellular response to starvation

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of nourishment.

FADS1, ALB, INHBB, RALB, SRD5A1, SREBF1, AKR1C3, DSC2, SREBF2, FOXO1, KLF10, BMPR2, GAS6, CARTPT, PDK4, KIAA1324, SFRP1, PCSK9, FBXO22, FNIP1, WNT2B, EHMT2, ZFYVE1, RRAGD, DNAJC15

GO:0009268

BP

response to pH

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus. pH is a measure of the acidity or basicity of an aqueous solution.

CA2, ARSB, GJA1, PAM, CLCN7

GO:0009298

BP

GDP-mannose biosynthetic process

The chemical reactions and pathways resulting in the formation of GDP-mannose, a substance composed of mannose in glycosidic linkage with guanosine diphosphate.

PMM2, GMPPB

GO:0009299

BP

mRNA transcription

The cellular synthesis of messenger RNA (mRNA) from a DNA template.

EREG, DDX5, HSF1, PPARD

GO:0009301

BP

snRNA transcription

The synthesis of small nuclear RNA (snRNA) from a DNA template.

SNAPC3

GO:0009303

BP

rRNA transcription

The synthesis of ribosomal RNA (rRNA), any RNA that forms part of the ribosomal structure, from a DNA template.

CD3EAP, NPM3, ANG, RNASEK, GTF3A, NIFK, POLR1E, SPIN1

GO:0009306

BP

protein secretion

The controlled release of proteins from a cell.

FGG, SCG2, PDIA4, CBLN1, CANX, ERP29, ARL4D, RAB8B, NECAB3, LMF1, ARFGAP3, CBLN4, SEL1L

GO:0009308

BP

amine metabolic process

The chemical reactions and pathways involving any organic compound that is weakly basic in character and contains an amino or a substituted amino group, as carried out by individual cells. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom.

AOC2, CYP1A1, VCAM1, AOC3

GO:0009311

BP

oligosaccharide metabolic process

The chemical reactions and pathways involving oligosaccharides, molecules with between two and (about) 20 monosaccharide residues connected by glycosidic linkages.

ST6GAL1, ST8SIA6, MGAT2, ST3GAL1, ST3GAL3, ST3GAL4, ST3GAL2, ST8SIA4, ST6GAL2, ST6GALNAC5, ST6GALNAC4, ST6GALNAC2, MAN1B1, ST3GAL6

GO:0009312

BP

oligosaccharide biosynthetic process

The chemical reactions and pathways resulting in the formation of oligosaccharides, molecules with between two and (about) 20 monosaccharide residues connected by glycosidic linkages.

B3GALT2, MPDU1, B4GALT1, MGAT2, ST6GALNAC5, FUT8

GO:0009313

BP

oligosaccharide catabolic process

The chemical reactions and pathways resulting in the breakdown of oligosaccharides, molecules with between two and (about) 20 monosaccharide residues connected by glycosidic linkages.

MAN2B1, GM2A, CTBS, NEU1, MAN2B2

GO:0009314

BP

response to radiation

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electromagnetic radiation stimulus. Electromagnetic radiation is a propagating wave in space with electric and magnetic components. These components oscillate at right angles to each other and to the direction of propagation.

ANGPT2, FANCG, MBD4, PENK, COL3A1, NTRK1, JUN, BCL2, TXN, KRT13, JUNB, JUND, CDC25A, CXCL12, SMC1A, ZAK, F11R, TNFRSF11A

GO:0009395

BP

phospholipid catabolic process

The chemical reactions and pathways resulting in the breakdown of phospholipids, any lipid containing phosphoric acid as a mono- or diester.

APOA2, PLCG2, PLA2G4A, ENPP2, NAPEPLD, ABHD6, LIPG

GO:0009396

BP

folic acid-containing compound biosynthetic process

The chemical reactions and pathways resulting in the formation of folic acid and its derivatives.

MTHFD2, MTHFS, MTHFD1L, MTHFD2L

GO:0009398

BP

FMN biosynthetic process

The chemical reactions and pathways resulting in the formation of FMN, the oxidized form of flavin mononucleotide (riboflavin 5'-(dihydrogen phosphate)), which acts as a coenzyme for a number of oxidative enzymes including NADH dehydrogenase.

RFK

GO:0009404

BP

toxin metabolic process

The chemical reactions and pathways involving a toxin, a poisonous compound (typically a protein) that is produced by cells or organisms and that can cause disease when introduced into the body or tissues of an organism.

PAM, CYP1B1, FMO2, AS3MT

GO:0009405

BP

pathogenesis

The set of specific processes that generate the ability of an organism to cause disease in another.

TMEM181