GO:0010608

BP

posttranscriptional regulation of gene expression

Any process that modulates the frequency, rate or extent of gene expression after the production of an RNA transcript.

PER1, ACE, MATR3, CAV1, PUM1, CDC37, GCNT2, PUM2, NANOS1, RC3H2

GO:0010609

BP

mRNA localization resulting in posttranscriptional regulation of gene expression

Any process that modulates the frequency, rate or extent of gene expression after the production of a mRNA transcript by its transport into, or maintainance in, a specific location within the cell.

MEX3D

GO:0010611

BP

regulation of cardiac muscle hypertrophy

Any process that modulates the rate, frequency or extent of the enlargement or overgrowth of all or part of the heart due to an increase in size (not length) of individual cardiac muscle fibers, without cell division.

AKAP13, LMCD1

GO:0010613

BP

positive regulation of cardiac muscle hypertrophy

Any process that increases the rate, frequency or extent of the enlargement or overgrowth of all or part of the heart due to an increase in size (not length) of individual cardiac muscle fibers, without cell division.

PDE5A, PDE9A, BMP10, AGT, IGF1, EDN1, PARP1, PRKCA, IL6ST, MTPN, MEF2A, CAMK2D, NR4A3

GO:0010614

BP

negative regulation of cardiac muscle hypertrophy

Any process that decreases the rate, frequency or extent of the enlargement or overgrowth of all or part of the heart due to an increase in size (not length) of individual cardiac muscle fibers, without cell division.

BMP10, RGS2, GSK3B, SMAD4, P2RX4

GO:0010621

BP

negative regulation of transcription by transcription factor localization

Any process that stops, prevents, or reduces the frequency, rate or extent of DNA-dependent transcription using a mechanism that involves the localization of a transcription factor.

ID1, HHEX

GO:0010623

BP

programmed cell death involved in cell development

The activation of endogenous cellular processes that result in the death of a cell as part of its development.

NTRK1

GO:0010626

BP

negative regulation of Schwann cell proliferation

Any process that decreases the frequency or extent of the multiplication or reproduction of Schwann cells, resulting in the expansion of their population. Schwann cells are a type of glial cell in the peripheral nervous system.

SKI, DICER1

GO:0010628

BP

positive regulation of gene expression

Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.

TLR4, PIK3CD, DDX3X, PDCD5, MUSK, PLSCR1, TLR3, KDM6A, KLF4, SPRY2, PARK2, TLR2, MITF, ROCK2, ZPR1, TADA3, ALDH1A2, KRAS, PDGFB, LDLR, TGFB1, NGF, INS, TNF, IL1A, IL1B, CRP, FN1, PF4, AMH, APOB, MYCN, TP53, IL6, CDK1, INHBA, VIM, CTSH, HSPA1A, HSPA1B, CCL3, AR, KIT, CD28, VDR, BMP2, EZR, CD46, VEGFA, IL7R, GJA1, ATF4, ERBB3, TNC, MT3, ITGA3, ITGB8, DNMT1, CALR, CTGF, ERP29, AVPR2, FGF9, PHB, RDX, BRCA1, STAT3, ID1, PIK3CB, PTGFR, NKX2-1, MAPK8, MAPK9, LIMS1, SLC11A1, PPM1F, STAR, SERPINB9, RAB27A, HMGA2, PRKAG1, WNT3, PLP1, CDC42, TGFB2, ACTA2, ACTG2, ACTC1, SRPK2, SMAD3, CDK6, HNRNPU, MDM2, E2F1, ANK2, ID2, MAP2K1, POU3F1, CAV1, TLE1, MEF2C, CNTN1, ANK3, GAS6, RAB3GAP1, RPS6KA2, TMED2, NR0B2, TWIST1, SMAD1, MAPK14, NTRK2, NFIL3, HIF1A, HFE, SFRP4, PID1, IQGAP3, LILRB1, CTCFL, OSR1, FUBP1, PAWR, SEC16B, QKI, GPER1, OLFM1, CITED1, CITED2, RBM4B, PDCD10, C1QTNF1, TRIM6, EPB41L4B, RGCC, TRPV4, DLL4, CYP26B1, DNMT3B, KDM5B, ZNF580, RIMS2, LAMP3, PTPN22, WNT6, NCOA3

GO:0010629

BP

negative regulation of gene expression

Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.

WWP2, ACACB, KLF4, PARK2, STC2, FGF19, PDGFB, LDLR, TGFB1, TNF, CRYAB, ESR1, FYN, RB1, PGR, CCL3, CD28, PC, ACE, MIF, CCNB1, CD46, NME1, GJA1, NFKB1, YY1, ITGB8, RBL1, CTGF, ERP29, AKT1, MAP2K2, ACVR1B, SERPINF1, CDKN1A, XDH, CDC42, TGFB2, RACK1, TMF1, ID2, MAP2K1, REL, MEF2C, AES, TARDBP, PICALM, HDAC1, DIP2A, NR0B2, RNASEH2B, PLAG1, IQGAP3, SFRP1, FLCN, ZNF503, MYADM, GPER1, OLFM1, CITED2, NDFIP1, UPK3B, PDCD10, BBS2, PINK1, TRIM6, MKKS, SLC35C2, DLL4, NDFIP2, TBK1, CNOT7, NOCT, SNX12, ZNF148, CNPY2, PTPN22

GO:0010631

BP

epithelial cell migration

The orderly movement of an epithelial cell from one site to another, often during the development of a multicellular organism.

PKN1, PKN2, NANOS1

GO:0010632

BP

regulation of epithelial cell migration

Any process that modulates the frequency, rate or extent of epithelial cell migration.

ARSB, PTK2, CORO1C, MACF1

GO:0010633

BP

negative regulation of epithelial cell migration

Any process that stops, prevents, or reduces the frequency, rate or extent of epithelial cell migration.

PTPRG, PBLD, SEMA3A, ADIPOR1, MARVELD3, EVL, CORO1C

GO:0010634

BP

positive regulation of epithelial cell migration

Any process that activates or increases the frequency, rate or extent of epithelial cell migration.

JUN, PFN1, CTSH, ITGA2, ITGA3, TGFBR2, SOX9, PPM1F, INSL3, TGFB2, RAB11A, ENPP2, BMPR2, HIF1A, GLIPR2, DOCK5, HDAC6

GO:0010635

BP

regulation of mitochondrial fusion

Any process that modulates the frequency, rate or extent of merging of two or more mitochondria within a cell to form a single compartment.

PID1

GO:0010636

BP

positive regulation of mitochondrial fusion

Any process that increases the frequency, rate or extent of merging of two or more mitochondria within a cell to form a single compartment.

PARK2, OPA1

GO:0010637

BP

negative regulation of mitochondrial fusion

Any process that decreases the frequency, rate or extent of merging of two or more mitochondria within a cell to form a single compartment.

PARK2, BNIP3, OMA1

GO:0010638

BP

positive regulation of organelle organization

Any process that increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle.

SURF4

GO:0010640

BP

regulation of platelet-derived growth factor receptor signaling pathway

Any process that modulates the frequency, rate or extent of the platelet-derived growth factor receptor signaling pathway.

LRIG2

GO:0010642

BP

negative regulation of platelet-derived growth factor receptor signaling pathway

Any process that stops, prevents, or reduces the frequency, rate or extent of the platelet-derived growth factor receptor signaling pathway.

APOD, SNCA, PTPRJ, ADIPOQ, NDRG4

GO:0010643

BP

cell communication by chemical coupling

The process that mediates signaling interactions between one cell and another cell by the transfer of small, water-soluble molecules or metabolites between their adjacent cytoplasms via intercellular protein channels.

GJA1, GJA5, DBN1

GO:0010644

BP

cell communication by electrical coupling

The process that mediates signaling interactions between one cell and another cell by transfer of current between their adjacent cytoplasms via intercellular protein channels.

GJA1, KCNA1, DBN1

GO:0010649

BP

regulation of cell communication by electrical coupling

Any process that modulates the frequency, rate or extent of cell communication via electrical coupling. Cell communication via electrical coupling is the process that mediates signaling interactions between one cell and another cell by transfer of current between their adjacent cytoplasms via intercellular protein channels.

SRI, CAMK2D

GO:0010650

BP

positive regulation of cell communication by electrical coupling

Any process that increases the frequency, rate or extent of cell communication via electrical coupling. Cell communication via electrical coupling is the process that mediates signaling interactions between one cell and another cell by transfer of current between their adjacent cytoplasms via intercellular protein channels.

ANK3

GO:0010652

BP

positive regulation of cell communication by chemical coupling

Any process that increases the frequency, rate or extent of cell communication via chemical coupling. Cell communication by chemical coupling is the process that mediates signaling interactions between one cell and another cell by the transfer of small, water-soluble molecules or metabolites between their adjacent cytoplasms via intercellular protein channels.

GJA1, GJA5

GO:0010656

BP

negative regulation of muscle cell apoptotic process

Any process that decreases the rate or frequency of muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a muscle cell and result in its death.

HMOX1

GO:0010657

BP

muscle cell apoptotic process

A form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle a muscle cell and result in its death. A muscle cell is a mature contractile cell, commonly known as a myocyte, that forms one of three kinds of muscle.

DMPK

GO:0010659

BP

cardiac muscle cell apoptotic process

A form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle a cardiac muscle cell and result in its death. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction.

NOL3, HSP90AA1, GNB1, RPS6KA2

GO:0010664

BP

negative regulation of striated muscle cell apoptotic process

Any process that increases the rate or extent of striated muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a striated muscle cell and result in its death.

HMGCR

GO:0010666

BP

positive regulation of cardiac muscle cell apoptotic process

Any process that increases the rate or extent of cardiac cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a cardiac muscle cell and result in its death.

AGT, HMGCR, CXCR2, LTK, BNIP3, CAMK2D, MAP3K5

GO:0010667

BP

negative regulation of cardiac muscle cell apoptotic process

Any process that decreases the rate or extent of cardiac cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a cardiac muscle cell and result in its death.

JAK2, NOL3, HSF1, ILK

GO:0010668

BP

ectodermal cell differentiation

The process in which relatively unspecialized cells acquire specialized structural and/or functional features of an ectodermal cell. Differentiation includes the processes involved in commitment of a cell to a specific fate.

ITGAM, ITGA6, VPS52

GO:0010669

BP

epithelial structure maintenance

A tissue homeostatic process required for the maintenance of epithelial structure.

LDB2, CXADR, CROCC, MKS1

GO:0010693

BP

negative regulation of alkaline phosphatase activity

Any process that decreases the frequency, rate or extent of alkaline phosphatase activity, the catalysis of the reaction: an orthophosphoric monoester + H2O = an alcohol + phosphate, with an alkaline pH optimum.

TNF, TGFB2

GO:0010694

BP

positive regulation of alkaline phosphatase activity

Any process that increases the frequency, rate or extent of alkaline phosphatase activity, the catalysis of the reaction: an orthophosphoric monoester + H2O = an alcohol + phosphate, with an alkaline pH optimum.

ITGA2, GPLD1, SMAD3, MEF2C, PPARGC1B

GO:0010700

BP

negative regulation of norepinephrine secretion

Any process that decreases the frequency, rate or extent of the regulated release of norepinephrine.

ADRA2B, AGTR2

GO:0010701

BP

positive regulation of norepinephrine secretion

Any process that increases the frequency, rate or extent of the regulated release of norepinephrine.

OXTR

GO:0010710

BP

regulation of collagen catabolic process

Any process that modulates the rate, frequency or extent of collagen catabolism. Collagen catabolism is the proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix.

ITGB1

GO:0010711

BP

negative regulation of collagen catabolic process

Any process that decreases the rate, frequency or extent of collagen catabolism. Collagen catabolism is the proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix.

CST3

GO:0010714

BP

positive regulation of collagen metabolic process

Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the metabolism of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals.

RETN

GO:0010715

BP

regulation of extracellular matrix disassembly

Any process that modulates the rate, frequency or extent of extracellular matrix disassembly. Extracellular matrix disassembly is a process that results in the breakdown of the extracellular matrix.

ETS1, DDR1

GO:0010716

BP

negative regulation of extracellular matrix disassembly

Any process that decreases the rate, frequency or extent of extracellular matrix disassembly. Extracellular matrix disassembly is a process that results in the breakdown of the extracellular matrix.

CST3, TGFB1, DPP4

GO:0010717

BP

regulation of epithelial to mesenchymal transition

Any process that modulates the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.

FAM195B, SMAD7, GREM1, EPHA3, TGFBR1, DAG1, PHLDB2, PHLDB1

GO:0010718

BP

positive regulation of epithelial to mesenchymal transition

Any process that increases the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition is where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.

SDCBP, TGFB1I1, TGFB1, COL1A1, BMP2, SERPINB3, CTNNB1, TGFBR1, TGFBR2, NOTCH1, TGFB2, SMAD3, DAB2, BAMBI, SMAD4, TWIST1, SMAD2, EZH2, GCNT2, HDAC2, OLFM1, GLIPR2, RGCC

GO:0010719

BP

negative regulation of epithelial to mesenchymal transition

Any process that decreases the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.

SMAD7, EFNA1, PBLD, NKX2-1, SFRP1, ADIPOR1, DACT3, TRIM62

GO:0010722

BP

regulation of ferrochelatase activity

Any process that modulates the frequency, rate or extent of ferrochelatase activity; catalysis of the reaction: protoporphyrin + Fe2+ = protoheme + 2 H+.

FXN

GO:0010724

BP

regulation of definitive erythrocyte differentiation

Any process that modulates the rate, frequency, or extent of definitive erythrocyte differentiation. Definitive erythrocyte differentiation occurs as part of the process of definitive hemopoiesis.

RBFOX2

GO:0010725

BP

regulation of primitive erythrocyte differentiation

Any process that modulates the rate, frequency, or extent of primitive erythrocyte differentiation. Primitive erythrocyte differentiation occurs as part of the process of primitive hemopoiesis.

KDM1A

GO:0010727

BP

negative regulation of hydrogen peroxide metabolic process

Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving hydrogen peroxide.

HDAC6

GO:0010729

BP

positive regulation of hydrogen peroxide biosynthetic process

Any process that increases the rate, frequency or extent of hydrogen peroxide biosynthesis. The chemical reactions and pathways resulting in the formation of hydrogen peroxide (H2O2), a potentially harmful byproduct of aerobic cellular respiration which can cause damage to DNA.

ZNF205

GO:0010730

BP

negative regulation of hydrogen peroxide biosynthetic process

Any process that decreases the rate, frequency or extent of hydrogen peroxide biosynthesis. The chemical reactions and pathways resulting in the formation of hydrogen peroxide (H2O2), a potentially harmful byproduct of aerobic cellular respiration which can cause damage to DNA.

STAT3

GO:0010734

BP

negative regulation of protein glutathionylation

Any process that decreases the rate, frequency, or extent of protein glutathionylation. Protein glutathionylation is the protein modification process in which a glutathione molecule is added to a protein amino acid through a disulfide linkage.

G6PD

GO:0010735

BP

positive regulation of transcription via serum response element binding

Any process that increases the frequency, rate or extent of the specifically regulated synthesis of RNA from DNA encoding a specific set of genes as a result of a transcription factor interacting with a serum response element (SRE). A serum response element is a short sequence with dyad symmetry found in the promoters of some of the cellular immediate-early genes, regulated by serum.

MICAL2

GO:0010737

BP

protein kinase A signaling

A series of reactions, mediated by the intracellular serine/threonine kinase protein kinase A, which occurs as a result of a single trigger reaction or compound.

GCG, LCP1, EZR, GAL, RDX

GO:0010738

BP

regulation of protein kinase A signaling

Any process that modulates the rate, frequency, or extent of protein kinase A signaling. PKA signaling is the series of reactions, mediated by the intracellular serine/threonine kinase protein kinase A, which occurs as a result of a single trigger reaction or compound.

AIP, FSHR, AKAP6, SPHKAP, AKAP1, AKAP7, AKAP11

GO:0010739

BP

positive regulation of protein kinase A signaling

Any process that increases the rate, frequency, or extent of protein kinase A signaling. PKA signaling is the series of reactions, mediated by the intracellular serine/threonine kinase protein kinase A, which occurs as a result of a single trigger reaction or compound.

MIF, ADIPOQ

GO:0010742

BP

macrophage derived foam cell differentiation

The process in which a monocyte acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions.

TGFB1, SOAT1, PPARG, EP300

GO:0010744

BP

positive regulation of macrophage derived foam cell differentiation

Any process that increases the rate, frequency or extent of macrophage derived foam cell differentiation. Macrophage derived foam cell differentiation is the process in which a macrophage acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions.

AGT, PF4, APOB, LPL, PLA2G2A, CD36, NFKB1, AGTR1, MAPK9, IL18

GO:0010745

BP

negative regulation of macrophage derived foam cell differentiation

Any process that decreases the rate, frequency or extent of macrophage derived foam cell differentiation. Macrophage derived foam cell differentiation is the process in which a macrophage acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions.

ABCA1, CRP, ITGB3, ITGAV, PPARG, NR1H2, PPARA, NR1H3, ADIPOQ, ABCA5

GO:0010748

BP

negative regulation of plasma membrane long-chain fatty acid transport

Any process that decreases the rate, frequency or extent of plasma membrane long-chain fatty acid transport. Plasma membrane long-chain fatty acid transport is the directed movement of long-chain fatty acids across the plasma membrane.

THBS1, AKT1, AKT2, IRS2

GO:0010751

BP

negative regulation of nitric oxide mediated signal transduction

Any process that decreases the rate, frequency or extent of nitric oxide mediated signal transduction. Nitric oxide mediated signal transduction is a series of molecular signals mediated by the detection of nitric oxide (NO).

SPINK1, THBS1, ATP2B4

GO:0010754

BP

negative regulation of cGMP-mediated signaling

Any process that decreases the rate, frequency or extent of cGMP-mediated signaling. cGMP-mediated signaling is a series of molecular signals in which a cell uses cyclic GMP to convert an extracellular signal into a response.

THBS1

GO:0010756

BP

positive regulation of plasminogen activation

Any process that increases the rate, frequency or extent of plasminogen activation. Plasminogen activation is the process in which plasminogen is processed to plasmin.

CLEC3B, MFI2, PLGRKT

GO:0010757

BP

negative regulation of plasminogen activation

Any process that decreases the rate, frequency or extent of plasminogen activation. Plasminogen activation is the process in which plasminogen is processed to plasmin.

SERPINE1, SERPINE2, THBS1, CPB2

GO:0010759

BP

positive regulation of macrophage chemotaxis

Any process that increases the rate, frequency or extent of macrophage chemotaxis. Macrophage chemotaxis is the movement of a macrophage in response to an external stimulus.

THBS1, CCL2, CCL5, C5AR1, RARRES2, TRPV4

GO:0010760

BP

negative regulation of macrophage chemotaxis

Any process that decreases the rate, frequency or extent of macrophage chemotaxis. Macrophage chemotaxis is the movement of a macrophage in response to an external stimulus.

CYP19A1

GO:0010761

BP

fibroblast migration

Cell migration that is accomplished by extension and retraction of a fibroblast pseudopodium. A fibroblast is a connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules.

ZFAND5, ILK, ARID5B, SYNE2, TNS1

GO:0010762

BP

regulation of fibroblast migration

Any process that modulates the rate, frequency or extent of fibroblast cell migration. Fibroblast cell migration is accomplished by extension and retraction of a pseudopodium.

SDC4, RAC1, GNA12, RFFL, CORO1C

GO:0010763

BP

positive regulation of fibroblast migration

Any process that increases the rate, frequency or extent of fibroblast cell migration. Fibroblast cell migration is accomplished by extension and retraction of a pseudopodium.

PAK3, TGFB1, THBS1, AKT1, ARHGEF7

GO:0010764

BP

negative regulation of fibroblast migration

Any process that decreases the rate, frequency or extent of fibroblast cell migration. Fibroblast cell migration is accomplished by extension and retraction of a pseudopodium.

ITGB1BP1, FGF2, HYAL2, CYGB, C5orf30

GO:0010765

BP

positive regulation of sodium ion transport

Any process that increases the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

AHCYL1, AKT1, FGF12, CNTN1, ANK3, CNKSR3, SGK3, PKP2, WNK3

GO:0010766

BP

negative regulation of sodium ion transport

Any process that decreases the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

SERPINE2

GO:0010767

BP

regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage

Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a UV damage stimulus.

CHEK1

GO:0010793

BP

regulation of mRNA export from nucleus

Any process that modulates the frequency, rate or extent of the directed movement of mRNA from the nucleus to the cytoplasm.

SUPT6H, ZC3H3

GO:0010795

BP

regulation of ubiquinone biosynthetic process

Any process that modulates the frequency, rate or extent of ubiquinone biosynthesis. Ubiquinone biosynthesis consists of the chemical reactions and pathways resulting in the formation of ubiquinone, a lipid-soluble electron-transporting coenzyme.

COQ3

GO:0010796

BP

regulation of multivesicular body size

Any process that modulates the volume of a multivesicular body, a type of late endosome in which regions of the limiting endosomal membrane invaginate to form internal vesicles.

RAB11A

GO:0010800

BP

positive regulation of peptidyl-threonine phosphorylation

Any process that increases the frequency, rate or extent of peptidyl-threonine phosphorylation. Peptidyl-threonine phosphorylation is the phosphorylation of peptidyl-threonine to form peptidyl-O-phospho-L-threonine.

AXIN1, RIPK2, TGFB1, GCG, MAPK1, CHI3L1, WNT5A, GSK3B, PLK1, CALM2, CEMIP, WNK3, TRIM6, SPHK1, TRPC6, CAB39

GO:0010801

BP

negative regulation of peptidyl-threonine phosphorylation

Any process that decreases the frequency, rate or extent of peptidyl-threonine phosphorylation. Peptidyl-threonine phosphorylation is the phosphorylation of peptidyl-threonine to form peptidyl-O-phospho-L-threonine.

SMAD7, SPRY2, CALM2, SPRED1, SIRT2, PARD3, INPP5K, DDIT4

GO:0010803

BP

regulation of tumor necrosis factor-mediated signaling pathway

Any process that modulates the rate or extent of the tumor necrosis factor-mediated signaling pathway. The tumor necrosis factor-mediated signaling pathway is the series of molecular signals generated as a consequence of tumor necrosis factor binding to a cell surface receptor.

TNF, UBC, TNFAIP3, SYK, RPS27A, UBA52, RACK1, TRAF1, BIRC3, RIPK1, CASP8, TRADD, TAX1BP1, CYLD, SPHK1, PYCARD

GO:0010804

BP

negative regulation of tumor necrosis factor-mediated signaling pathway

Any process that decreases the rate or extent of the tumor necrosis factor-mediated signaling pathway. The tumor necrosis factor-mediated signaling pathway is the series of molecular signals generated as a consequence of tumor necrosis factor binding to a cell surface receptor.

NOL3, APOA1, GSTP1, PTPN2, F2RL1, GAS6, ADIPOQ, ZNF675, RFFL, NR1H4

GO:0010807

BP

regulation of synaptic vesicle priming

Any process that modulates the frequency, rate or extent of synaptic vesicle priming. Synaptic vesicle priming is the formation of SNARE-containing complexes, bringing synaptic vesicle membrane and plasma membranes into close proximity and thereby facilitating membrane fusion.

STXBP1

GO:0010810

BP

regulation of cell-substrate adhesion

Any process that modulates the frequency, rate or extent of cell-substrate adhesion. Cell-substrate adhesion is the attachment of a cell to the underlying substrate via adhesion molecules.

RAC2, ATXN3

GO:0010811

BP

positive regulation of cell-substrate adhesion

Any process that increases the frequency, rate or extent of cell-substrate adhesion. Cell-substrate adhesion is the attachment of a cell to the underlying substrate via adhesion molecules.

CYR61, EDIL3, JAK2, ECM2, VTN, ITGA5, NID1, ALOX15, ITGA6, ITGA3, LIMS1, NPY2R, PPM1F, RAC1, FBLN2, HSD17B12, CCDC80, NDNF, SPOCK2, SMOC2

GO:0010812

BP

negative regulation of cell-substrate adhesion

Any process that decreases the frequency, rate or extent of cell-substrate adhesion. Cell-substrate adhesion is the attachment of a cell to the underlying substrate via adhesion molecules.

ANGPT2, FZD7, PLG, COL1A1, LGALS1, NOTCH1, PTPRO, GCNT2, TBCD, FZD4

GO:0010813

BP

neuropeptide catabolic process

The chemical reactions and pathways resulting in the breakdown of neuropeptides. Neuropeptides are signaling peptides that travel across a synaptic junction.

CTSH

GO:0010814

BP

substance P catabolic process

The chemical reactions and pathways resulting in the breakdown of the neuropeptide substance P.

ECE1

GO:0010815

BP

bradykinin catabolic process

The chemical reactions and pathways resulting in the breakdown of the peptide bradykinin.

CTSH, IDE, CPN1, ECE1

GO:0010816

BP

calcitonin catabolic process

The chemical reactions and pathways resulting in the breakdown of the peptide calcitonin.

ECE1

GO:0010817

BP

regulation of hormone levels

Any process that modulates the levels of hormone within an organism or a tissue. A hormone is any substance formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells in the same organism, upon which it has a specific regulatory action.

SOX8

GO:0010818

BP

T cell chemotaxis

The directed movement of a T cell in response to an external stimulus. A T cell is a type of lymphocyte whose defining characteristic is the expression of a T cell receptor complex.

PIK3CD, CCL3, GPR183, PIK3CG, CXCL16

GO:0010820

BP

positive regulation of T cell chemotaxis

Any process that increases the rate, frequency or extent of T cell chemotaxis. T cell chemotaxis is the directed movement of a T cell in response to an external stimulus.

ADAM10, CCL5, S100A7, WNT5A, ADAM17

GO:0010821

BP

regulation of mitochondrion organization

Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a mitochondrion.

PARK2, SQSTM1, MGARP, PINK1, MFF, ATP13A2

GO:0010822

BP

positive regulation of mitochondrion organization

Any process that increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a mitochondrion.

MGARP, PPARGC1A

GO:0010823

BP

negative regulation of mitochondrion organization

Any process that decreases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a mitochondrion.

FLCN

GO:0010824

BP

regulation of centrosome duplication

Any process that modulates the frequency, rate or extent of centrosome duplication. Centrosome duplication is the replication of a centrosome, a structure comprised of a pair of centrioles and peri-centriolar material from which a microtubule spindle apparatus is organized.

XPO1, CHMP2A, VPS4B, PDCD6IP, FBXW5, CHMP4B, CHORDC1

GO:0010825

BP

positive regulation of centrosome duplication

Any process that increases the frequency, rate or extent of centrosome duplication. Centrosome duplication is the replication of a centrosome, a structure comprised of a pair of centrioles and peri-centriolar material from which a microtubule spindle apparatus is organized.

ROCK2, CEP120

GO:0010826

BP

negative regulation of centrosome duplication

Any process that decreases the frequency, rate or extent of centrosome duplication. Centrosome duplication is the replication of a centrosome, a structure comprised of a pair of centrioles and peri-centriolar material from which a microtubule spindle apparatus is organized.

NPM1, CCNF

GO:0010827

BP

regulation of glucose transport

Any process that modulates the frequency, rate or extent of glucose transport. Glucose transport is the directed movement of the hexose monosaccharide glucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

NUPL2, NUP155, TPR, NUP62, NUP153, RANBP2, NUP107, RAE1, NUP160, NUP93, NUP43, NUP37, NUP35, NUP210, NUP205, SEH1L, TRIB3, NUP88, NDC1, NUP58, NUP85, NUP50

GO:0010828

BP

positive regulation of glucose transport

Any process that increases the frequency, rate or extent of glucose transport. Glucose transport is the directed movement of the hexose monosaccharide glucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

C3, C2CD5, NR4A3

GO:0010829

BP

negative regulation of glucose transport

Any process that decreases the frequency, rate or extent of glucose transport. Glucose transport is the directed movement of the hexose monosaccharide glucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

IL1B, PRKCB, INPP5K