Search Geneontologies

Geneontologies

GO ID Ontology GO Term Term Definition Proteins

GO:1902751

BP

positive regulation of cell cycle G2/M phase transition

Any process that activates or increases the frequency, rate or extent of cell cycle G2/M phase transition.

NPM1

GO:1902766

BP

skeletal muscle satellite cell migration

The orderly movement of a skeletal muscle satellite cell from one site to another. Migration of these cells is a key step in the process of growth and repair of skeletal muscle cells.

RHOA

GO:1902771

BP

positive regulation of choline O-acetyltransferase activity

Any process that activates or increases the frequency, rate or extent of choline O-acetyltransferase activity.

SORL1

GO:1902774

BP

late endosome to lysosome transport

The directed movement of substances from late endosome to lysosome.

SNAPIN

GO:1902775

BP

mitochondrial large ribosomal subunit assembly

The aggregation, arrangement and bonding together of a set of components to form a mitochondrial large ribosomal subunit.

DHX30, DDX28

GO:1902803

BP

regulation of synaptic vesicle transport

Any process that modulates the frequency, rate or extent of synaptic vesicle transport.

PARK2, PINK1

GO:1902806

BP

regulation of cell cycle G1/S phase transition

Any process that modulates the frequency, rate or extent of cell cycle G1/S phase transition.

ATP2B4

GO:1902808

BP

positive regulation of cell cycle G1/S phase transition

Any process that activates or increases the frequency, rate or extent of cell cycle G1/S phase transition.

PHB2, PAGR1, FAM83D

GO:1902809

BP

regulation of skeletal muscle fiber differentiation

Any process that modulates the frequency, rate or extent of skeletal muscle fiber differentiation.

NLN

GO:1902823

BP

negative regulation of late endosome to lysosome transport

Any process that stops, prevents or reduces the frequency, rate or extent of late endosome to lysosome transport.

VPS35

GO:1902824

BP

positive regulation of late endosome to lysosome transport

Any process that activates or increases the frequency, rate or extent of late endosome to lysosome transport.

SNAPIN, ARF1

GO:1902828

BP

positive regulation of L-arginine import into cell

Any process that activates or increases the frequency, rate or extent of L-arginine import into cell.

AGT

GO:1902847

BP

regulation of neuronal signal transduction

Any process that modulates the frequency, rate or extent of neuronal signal transduction.

CLU

GO:1902850

BP

microtubule cytoskeleton organization involved in mitosis

Any microtubule cytoskeleton organization that is involved in mitosis.

TACC3

GO:1902856

BP

negative regulation of nonmotile primary cilium assembly

Any process that stops, prevents or reduces the frequency, rate or extent of nonmotile primary cilium assembly.

MAK

GO:1902857

BP

positive regulation of nonmotile primary cilium assembly

Any process that activates or increases the frequency, rate or extent of nonmotile primary cilium assembly.

SEPT7, CEP135, CENPJ, WRAP73

GO:1902861

BP

copper ion import into cell

The directed movement of copper ions from outside of a cell into the cytoplasmic compartment. This may occur via transport across the plasma membrane or via endocytosis.

SLC31A1

GO:1902884

BP

positive regulation of response to oxidative stress

Any process that activates or increases the frequency, rate or extent of response to oxidative stress.

SEPN1

GO:1902891

BP

negative regulation of root hair elongation

Any process that stops, prevents or reduces the frequency, rate or extent of root hair elongation.

GAL

GO:1902894

BP

negative regulation of pri-miRNA transcription from RNA polymerase II promoter

Any process that stops, prevents or reduces the frequency, rate or extent of pri-miRNA transcription from RNA polymerase II promoter.

NFIB, PDGFB, SOX9, PPARD, PPARA, NFATC4

GO:1902895

BP

positive regulation of pri-miRNA transcription from RNA polymerase II promoter

Any process that activates or increases the frequency, rate or extent of pri-miRNA transcription from RNA polymerase II promoter.

SMAD6, FOS, PDGFB, TGFB1, JUN, NGFR, BMP2, BMP4, BMPR1A, STAT3, SMARCA4, SMAD3, RELA, SMAD1, HIF1A, GNL3

GO:1902896

BP

terminal web assembly

The aggregation, arrangement and bonding together of a set of components to form a terminal web.

EZR, PLS1

GO:1902897

BP

regulation of postsynaptic density protein 95 clustering

Any process that modulates the frequency, rate or extent of postsynaptic density protein 95 clustering.

CDH2, CRIPT

GO:1902902

BP

negative regulation of autophagosome assembly

Any process that stops, prevents or reduces the frequency, rate or extent of autophagosome assembly.

MTM1, FEZ1, PINK1, CHMP4B

GO:1902905

BP

positive regulation of fibril organization

Any process that activates or increases the frequency, rate or extent of fibril organization.

GPX1

GO:1902916

BP

positive regulation of protein polyubiquitination

Any process that activates or increases the frequency, rate or extent of protein polyubiquitination.

SKP2

GO:1902943

BP

positive regulation of voltage-gated chloride channel activity

Any process that activates or increases the frequency, rate or extent of voltage-gated chloride channel activity.

CFTR, PTAFR

GO:1902946

BP

protein localization to early endosome

A process in which a protein is transported to, or maintained in, a location within an early endosome.

NRP1

GO:1902947

BP

regulation of tau-protein kinase activity

Any process that modulates the frequency, rate or extent of tau-protein kinase activity.

HGF

GO:1902948

BP

negative regulation of tau-protein kinase activity

Any process that stops, prevents or reduces the frequency, rate or extent of tau-protein kinase activity.

SORL1

GO:1902949

BP

positive regulation of tau-protein kinase activity

Any process that activates or increases the frequency, rate or extent of tau-protein kinase activity.

CLU

GO:1902952

BP

positive regulation of dendritic spine maintenance

Any process that activates or increases the frequency, rate or extent of dendritic spine maintenance.

APOE

GO:1902953

BP

positive regulation of ER to Golgi vesicle-mediated transport

Any process that activates or increases the frequency, rate or extent of ER to Golgi vesicle-mediated transport.

ARF1, SORL1

GO:1902955

BP

positive regulation of early endosome to recycling endosome transport

Any process that activates or increases the frequency, rate or extent of early endosome to recycling endosome transport.

SORL1

GO:1902957

BP

negative regulation of mitochondrial electron transport, NADH to ubiquinone

Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial electron transport, NADH to ubiquinone.

SNCA, DNAJC15

GO:1902958

BP

positive regulation of mitochondrial electron transport, NADH to ubiquinone

Any process that activates or increases the frequency, rate or extent of mitochondrial electron transport, NADH to ubiquinone.

PINK1

GO:1902959

BP

regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process

Any process that modulates the frequency, rate or extent of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process.

PICALM

GO:1902960

BP

negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process

Any process that stops, prevents or reduces the frequency, rate or extent of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process.

SORL1

GO:1902961

BP

positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process

Any process that activates or increases the frequency, rate or extent of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process.

PICALM

GO:1902963

BP

negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process

Any process that stops, prevents or reduces the frequency, rate or extent of metalloendopeptidase activity involved in amyloid precursor protein catabolic process.

PICALM, SORL1

GO:1902966

BP

positive regulation of protein localization to early endosome

Any process that activates or increases the frequency, rate or extent of protein localization to early endosome.

EZR, RDX, SORL1

GO:1902975

BP

mitotic DNA replication initiation

Any DNA replication initiation involved in mitotic cell cycle DNA replication.

GINS2

GO:1902979

BP

mitotic DNA replication termination

Any DNA replication termination involved in mitotic cell cycle DNA replication.

RTFDC1

GO:1902983

BP

DNA strand elongation involved in mitotic DNA replication

Any DNA strand elongation involved in mitotic cell cycle DNA replication.

GINS1

GO:1902990

BP

mitotic telomere maintenance via semi-conservative replication

Any telomere maintenance via semi-conservative replication that is involved in mitotic cell cycle.

PCNA, DNA2

GO:1902995

BP

positive regulation of phospholipid efflux

Any process that activates or increases the frequency, rate or extent of phospholipid efflux.

APOE

GO:1902997

BP

negative regulation of neurofibrillary tangle assembly

Any process that stops, prevents or reduces the frequency, rate or extent of neurofibrillary tangle assembly.

SORL1

GO:1902998

BP

positive regulation of neurofibrillary tangle assembly

Any process that activates or increases the frequency, rate or extent of neurofibrillary tangle assembly.

CLU

GO:1903002

BP

positive regulation of lipid transport across blood brain barrier

Any process that activates or increases the frequency, rate or extent of lipid transport across blood brain barrier.

APOE

GO:1903003

BP

positive regulation of protein deubiquitination

Any process that activates or increases the frequency, rate or extent of protein deubiquitination.

TANK

GO:1903006

BP

positive regulation of protein K63-linked deubiquitination

Any process that activates or increases the frequency, rate or extent of protein K63-linked deubiquitination.

VCP

GO:1903007

BP

positive regulation of Lys63-specific deubiquitinase activity

Any process that activates or increases the frequency, rate or extent of Lys63-specific deubiquitinase activity.

VCP

GO:1903010

BP

regulation of bone development

Any process that modulates the frequency, rate or extent of bone development.

GLI3

GO:1903011

BP

negative regulation of bone development

Any process that stops, prevents or reduces the frequency, rate or extent of bone development.

RGN

GO:1903016

BP

negative regulation of exo-alpha-sialidase activity

Any process that stops, prevents or reduces the frequency, rate or extent of exo-alpha-sialidase activity.

APCS, PTX3

GO:1903019

BP

negative regulation of glycoprotein metabolic process

Any process that stops, prevents or reduces the frequency, rate or extent of glycoprotein metabolic process.

APCS, PTX3

GO:1903020

BP

positive regulation of glycoprotein metabolic process

Any process that activates or increases the frequency, rate or extent of glycoprotein metabolic process.

RAB1A, RAB1B

GO:1903025

BP

regulation of RNA polymerase II regulatory region sequence-specific DNA binding

Any process that modulates the frequency, rate or extent of RNA polymerase II regulatory region sequence-specific DNA binding.

LIF

GO:1903026

BP

negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding

Any process that stops, prevents or reduces the frequency, rate or extent of RNA polymerase II regulatory region sequence-specific DNA binding.

DDIT3, ID1

GO:1903033

BP

positive regulation of microtubule plus-end binding

Any process that activates or increases the frequency, rate or extent of microtubule plus-end binding.

MAPRE1, MAPRE3

GO:1903034

BP

regulation of response to wounding

Any process that modulates the frequency, rate or extent of response to wounding.

IL10

GO:1903038

BP

negative regulation of leukocyte cell-cell adhesion

Any process that stops, prevents or reduces the frequency, rate or extent of leukocyte cell-cell adhesion.

ASS1, PPARA

GO:1903044

BP

protein localization to membrane raft

A process in which a protein is transported to, or maintained in, a location within a membrane raft.

FLOT1, RFTN1

GO:1903045

BP

neural crest cell migration involved in sympathetic nervous system development

Any neural crest cell migration that is involved in sympathetic nervous system development.

SEMA3A

GO:1903047

BP

mitotic cell cycle process

A process that is part of the mitotic cell cycle.

KIF14

GO:1903052

BP

positive regulation of proteolysis involved in cellular protein catabolic process

Any process that activates or increases the frequency, rate or extent of proteolysis involved in cellular protein catabolic process.

CTSC, RGN

GO:1903053

BP

regulation of extracellular matrix organization

Any process that modulates the frequency, rate or extent of extracellular matrix organization.

TCF15

GO:1903056

BP

regulation of melanosome organization

Any process that modulates the frequency, rate or extent of melanosome organization.

ZEB2

GO:1903061

BP

positive regulation of protein lipidation

Any process that activates or increases the frequency, rate or extent of protein lipidation.

RAB3GAP1, SVIP, RAB3GAP2

GO:1903070

BP

negative regulation of ER-associated ubiquitin-dependent protein catabolic process

Any process that stops, prevents or reduces the frequency, rate or extent of ER-associated ubiquitin-dependent protein catabolic process.

SVIP

GO:1903071

BP

positive regulation of ER-associated ubiquitin-dependent protein catabolic process

Any process that activates or increases the frequency, rate or extent of ER-associated ubiquitin-dependent protein catabolic process.

SGTA, BCAP31, CAV1

GO:1903076

BP

regulation of protein localization to plasma membrane

Any process that modulates the frequency, rate or extent of protein localization to plasma membrane.

STX7, GBP1, SPTBN1, VTI1B

GO:1903077

BP

negative regulation of protein localization to plasma membrane

Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to plasma membrane.

TGFB1, GBP1, NUMB, DAB2, AP2M1

GO:1903078

BP

positive regulation of protein localization to plasma membrane

Any process that activates or increases the frequency, rate or extent of protein localization to plasma membrane.

SPTBN1, STX4, STX3

GO:1903126

BP

negative regulation of centriole-centriole cohesion

Any process that stops, prevents or reduces the frequency, rate or extent of centriole-centriole cohesion.

NEK2

GO:1903140

BP

regulation of establishment of endothelial barrier

Any process that modulates the frequency, rate or extent of establishment of endothelial barrier.

ROCK2, TNF, IL1B

GO:1903141

BP

negative regulation of establishment of endothelial barrier

Any process that stops, prevents or reduces the frequency, rate or extent of establishment of endothelial barrier.

S1PR3

GO:1903142

BP

positive regulation of establishment of endothelial barrier

Any process that activates or increases the frequency, rate or extent of establishment of endothelial barrier.

CDH5

GO:1903146

BP

regulation of mitophagy

Any process that modulates the frequency, rate or extent of mitochondrion degradation (mitophagy).

HAX1, BNIP3L, ACTL6A, SREBF1, CTSK, RPL28, SREBF2, ZBTB17, CTTN, PINK1, MAP1LC3B, ATP13A2, USP36, HDAC6, RUVBL1

GO:1903147

BP

negative regulation of mitophagy

Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrion degradation (mitophagy).

TSPO, PINK1

GO:1903169

BP

regulation of calcium ion transmembrane transport

Any process that modulates the frequency, rate or extent of calcium ion transmembrane transport.

TSPAN13, PIK3CG

GO:1903170

BP

negative regulation of calcium ion transmembrane transport

Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion transmembrane transport.

ATP1A2

GO:1903202

BP

negative regulation of oxidative stress-induced cell death

Any process that stops, prevents or reduces the frequency, rate or extent of oxidative stress-induced cell death.

PARK2, PINK1

GO:1903204

BP

negative regulation of oxidative stress-induced neuron death

Any process that stops, prevents or reduces the frequency, rate or extent of oxidative stress-induced neuron death.

ATF4, PINK1

GO:1903206

BP

negative regulation of hydrogen peroxide-induced cell death

Any process that stops, prevents or reduces the frequency, rate or extent of hydrogen peroxide-induced cell death.

GPR37, PSAP, TXN, NUP93

GO:1903208

BP

negative regulation of hydrogen peroxide-induced neuron death

Any process that stops, prevents or reduces the frequency, rate or extent of hydrogen peroxide-induced neuron death.

RACK1, NR4A3

GO:1903214

BP

regulation of protein targeting to mitochondrion

Any process that modulates the frequency, rate or extent of protein targeting to mitochondrion.

HAX1, BNIP3L, PARK2, SREBF1, PINK1

GO:1903225

BP

negative regulation of endodermal cell differentiation

Any process that stops, prevents or reduces the frequency, rate or extent of endodermal cell differentiation.

COL5A2, COL5A1

GO:1903232

BP

melanosome assembly

The aggregation, arrangement and bonding together of a set of components to form a melanosome, a tissue-specific, membrane-bounded cytoplasmic organelle within which melanin pigments are synthesized and stored.

TRAPPC6A, RAB32, HPS1, HPS4

GO:1903233

BP

regulation of calcium ion-dependent exocytosis of neurotransmitter

Any process that modulates the frequency, rate or extent of calcium ion-dependent exocytosis of neurotransmitter.

ATP2A2, RAB3GAP1

GO:1903237

BP

negative regulation of leukocyte tethering or rolling

Any process that stops, prevents or reduces the frequency, rate or extent of leukocyte tethering or rolling.

CXCL12

GO:1903238

BP

positive regulation of leukocyte tethering or rolling

Any process that activates or increases the frequency, rate or extent of leukocyte tethering or rolling.

PTAFR

GO:1903242

BP

regulation of cardiac muscle hypertrophy in response to stress

Any process that modulates the frequency, rate or extent of cardiac muscle hypertrophy in response to stress.

BMP10

GO:1903243

BP

negative regulation of cardiac muscle hypertrophy in response to stress

Any process that stops, prevents or reduces the frequency, rate or extent of cardiac muscle hypertrophy in response to stress.

ATP2B4, ERRFI1

GO:1903244

BP

positive regulation of cardiac muscle hypertrophy in response to stress

Any process that activates or increases the frequency, rate or extent of cardiac muscle hypertrophy in response to stress.

PPP3CA, TRPC3

GO:1903249

BP

negative regulation of citrulline biosynthetic process

Any process that stops, prevents or reduces the frequency, rate or extent of citrulline biosynthetic process.

ATP2B4

GO:1903262

BP

negative regulation of serine phosphorylation of STAT3 protein

Any process that stops, prevents or reduces the frequency, rate or extent of serine phosphorylation of STAT3 protein.

PWP1

GO:1903265

BP

positive regulation of tumor necrosis factor-mediated signaling pathway

Any process that activates or increases the frequency, rate or extent of tumor necrosis factor-mediated signaling pathway.

PARK2, HSPA1A, HSPA1B

GO:1903278

BP

positive regulation of sodium ion export from cell

Any process that activates or increases the frequency, rate or extent of sodium ion export from cell.

FXYD1, ATP1B1, ATP1B3

GO:1903280

BP

negative regulation of calcium:sodium antiporter activity

Any process that stops, prevents or reduces the frequency, rate or extent of calcium:sodium antiporter activity.

ATP1A2