Search Geneontologies

Geneontologies

GO ID Ontology GO Term Term Definition Proteins

GO:1902176

BP

negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway

Any process that stops, prevents or reduces the frequency, rate or extent of an oxidative stress-induced intrinsic apoptotic signaling pathway.

NOL3, VNN1, INS, SOD2, HSPB1, GPX1, AKT1, MAPK7, BAG5

GO:1902177

BP

positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway

Any process that activates or increases the frequency, rate or extent of an oxidative stress-induced intrinsic apoptotic signaling pathway.

SFPQ

GO:1902186

BP

regulation of viral release from host cell

Any process that modulates the frequency, rate or extent of viral release from host cell.

TRIM25, TRIM62

GO:1902187

BP

negative regulation of viral release from host cell

Any process that stops, prevents or reduces the frequency, rate or extent of viral release from host cell.

TRIM13, TRIM26, TRIM28, TRIM25, TRIM8, TRIM35

GO:1902188

BP

positive regulation of viral release from host cell

Any process that activates or increases the frequency, rate or extent of viral release from host cell.

CHMP2A, VPS4B, CHMP4B

GO:1902202

BP

regulation of hepatocyte growth factor receptor signaling pathway

Any process that modulates the frequency, rate or extent of hepatocyte growth factor receptor signaling pathway.

PTPN2

GO:1902203

BP

negative regulation of hepatocyte growth factor receptor signaling pathway

Any process that stops, prevents or reduces the frequency, rate or extent of hepatocyte growth factor receptor signaling pathway.

ADAMTS12

GO:1902204

BP

positive regulation of hepatocyte growth factor receptor signaling pathway

Any process that activates or increases the frequency, rate or extent of hepatocyte growth factor receptor signaling pathway.

ESM1

GO:1902206

BP

negative regulation of interleukin-2-mediated signaling pathway

Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-2-mediated signaling pathway.

PTPN2

GO:1902212

BP

negative regulation of prolactin signaling pathway

Any process that stops, prevents or reduces the frequency, rate or extent of prolactin signaling pathway.

PTPN2

GO:1902213

BP

positive regulation of prolactin signaling pathway

Any process that activates or increases the frequency, rate or extent of prolactin signaling pathway.

CREBRF

GO:1902215

BP

negative regulation of interleukin-4-mediated signaling pathway

Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-4-mediated signaling pathway.

PTPN2

GO:1902219

BP

negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress

Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to osmotic stress.

ARHGEF2

GO:1902227

BP

negative regulation of macrophage colony-stimulating factor signaling pathway

Any process that stops, prevents or reduces the frequency, rate or extent of macrophage colony-stimulating factor signaling pathway.

PTPN2

GO:1902230

BP

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage

Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to DNA damage.

SNAI2, CLU, TPT1, CXCL12, CCAR2

GO:1902231

BP

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage

Any process that activates or increases the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to DNA damage.

SKIL, FBXO18, RAD9A

GO:1902233

BP

negative regulation of positive thymic T cell selection

Any process that stops, prevents or reduces the frequency, rate or extent of positive thymic T cell selection.

PTPN2

GO:1902235

BP

regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway

Any process that modulates the frequency, rate or extent of an endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway.

ERP29

GO:1902236

BP

negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway

Any process that stops, prevents or reduces the frequency, rate or extent of an endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway.

PARK2, OPA1, HSPA1A, HSPA1B, XBP1, GRINA, SYVN1, CREB3L1, VIMP

GO:1902237

BP

positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway

Any process that activates or increases the frequency, rate or extent of an endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway.

BCL2L11, PTPN2, DDIT3, SERINC3, PMAIP1

GO:1902254

BP

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator

Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway by p53 class mediator.

PARK2, PTTG1IP, RRN3

GO:1902256

BP

regulation of apoptotic process involved in outflow tract morphogenesis

Any process that modulates the frequency, rate or extent of apoptotic process involved in outflow tract morphogenesis.

TGFB2

GO:1902257

BP

negative regulation of apoptotic process involved in outflow tract morphogenesis

Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in outflow tract morphogenesis.

FOXC1

GO:1902259

BP

regulation of delayed rectifier potassium channel activity

Any process that modulates the frequency, rate or extent of delayed rectifier potassium channel activity.

VAMP2, KCNG1

GO:1902260

BP

negative regulation of delayed rectifier potassium channel activity

Any process that stops, prevents or reduces the frequency, rate or extent of delayed rectifier potassium channel activity.

ANK3

GO:1902261

BP

positive regulation of delayed rectifier potassium channel activity

Any process that activates or increases the frequency, rate or extent of delayed rectifier potassium channel activity.

AKAP6

GO:1902262

BP

apoptotic process involved in patterning of blood vessels

Any apoptotic process that is involved in patterning of blood vessels.

LRP5, BAX

GO:1902263

BP

apoptotic process involved in embryonic digit morphogenesis

Any apoptotic process that is involved in embryonic digit morphogenesis.

BCL2L11, NOTCH1, BAX

GO:1902268

BP

negative regulation of polyamine transmembrane transport

Any process that stops, prevents or reduces the frequency, rate or extent of polyamine transmembrane transport.

OAZ2, OAZ1

GO:1902269

BP

positive regulation of polyamine transmembrane transport

Any process that activates or increases the frequency, rate or extent of polyamine transmembrane transport.

AZIN1

GO:1902275

BP

regulation of chromatin organization

Any process that modulates the frequency, rate or extent of chromatin organization.

MKI67

GO:1902283

BP

negative regulation of primary amine oxidase activity

Any process that stops, prevents or reduces the frequency, rate or extent of primary amine oxidase activity.

PARK2

GO:1902285

BP

semaphorin-plexin signaling pathway involved in neuron projection guidance

Any semaphorin-plexin signaling pathway that is involved in neuron projection guidance.

NRP1, NRP2, SEMA3A

GO:1902287

BP

semaphorin-plexin signaling pathway involved in axon guidance

Any semaphorin-plexin signaling pathway that is involved in axon guidance.

NRP1, PLXNB2, PLXNC1, PLXNA2, PLXNA3, SEMA3A, PLXNA1, PLXND1

GO:1902303

BP

negative regulation of potassium ion export

Any process that stops, prevents or reduces the frequency, rate or extent of potassium ion export.

KCNH2

GO:1902304

BP

positive regulation of potassium ion export

Any process that activates or increases the frequency, rate or extent of potassium ion export.

ANO6

GO:1902305

BP

regulation of sodium ion transmembrane transport

Any process that modulates the frequency, rate or extent of sodium ion transmembrane transport.

ATP2B4, FGF12, DLG1, SNTA1, RANGRF

GO:1902306

BP

negative regulation of sodium ion transmembrane transport

Any process that stops, prevents or reduces the frequency, rate or extent of sodium ion transmembrane transport.

CAMK2D, COMMD1, NEDD4L

GO:1902307

BP

positive regulation of sodium ion transmembrane transport

Any process that activates or increases the frequency, rate or extent of sodium ion transmembrane transport.

ARF1

GO:1902309

BP

negative regulation of peptidyl-serine dephosphorylation

Any process that stops, prevents or reduces the frequency, rate or extent of peptidyl-serine dephosphorylation.

YWHAE

GO:1902310

BP

positive regulation of peptidyl-serine dephosphorylation

Any process that activates or increases the frequency, rate or extent of peptidyl-serine dephosphorylation.

PPP1R15A, DUSP26

GO:1902311

BP

regulation of copper ion transmembrane transport

Any process that modulates the frequency, rate or extent of copper ion transmembrane transport.

SLC31A2

GO:1902336

BP

positive regulation of retinal ganglion cell axon guidance

Any process that activates or increases the frequency, rate or extent of retinal ganglion cell axon guidance.

NRP1, VEGFA

GO:1902340

BP

negative regulation of chromosome condensation

Any process that stops, prevents or reduces the frequency, rate or extent of chromosome condensation.

H3F3A

GO:1902358

BP

sulfate transmembrane transport

The directed movement of sulfate across a membrane.

SLC26A2, SLC26A11, SLC26A1

GO:1902378

BP

VEGF-activated neuropilin signaling pathway involved in axon guidance

Any VEGF-activated neuropilin signaling pathway that is involved in axon guidance.

NRP1

GO:1902380

BP

positive regulation of endoribonuclease activity

Any process that activates or increases the frequency, rate or extent of endoribonuclease activity.

HSPA1A, HSPA1B

GO:1902396

BP

protein localization to bicellular tight junction

A process in which a protein is transported to, or maintained in, a location within a tight junction.

ACTN4

GO:1902410

BP

mitotic cytokinetic process

Any cytokinetic process that is involved in mitotic cell cycle.

CNTROB

GO:1902414

BP

protein localization to cell junction

A process in which a protein is transported to, or maintained in, a location within a cell junction.

MARVELD3

GO:1902415

BP

regulation of mRNA binding

Any process that modulates the frequency, rate or extent of mRNA binding.

CARM1

GO:1902416

BP

positive regulation of mRNA binding

Any process that activates or increases the frequency, rate or extent of mRNA binding.

FMR1

GO:1902430

BP

negative regulation of beta-amyloid formation

Any process that stops, prevents or reduces the frequency, rate or extent of beta-amyloid formation.

APOE, CLU, SORL1

GO:1902445

BP

regulation of mitochondrial membrane permeability involved in programmed necrotic cell death

Any regulation of mitochondrial membrane permeability that is involved in programmed necrotic cell death.

PPIF, BAX, ALKBH7

GO:1902455

BP

negative regulation of stem cell population maintenance

Any process that stops, prevents or reduces the frequency, rate or extent of stem cell population maintenance.

ZNF706

GO:1902459

BP

positive regulation of stem cell population maintenance

Any process that activates or increases the frequency, rate or extent of stem cell population maintenance.

YAP1

GO:1902462

BP

positive regulation of mesenchymal stem cell proliferation

Any process that activates or increases the frequency, rate or extent of mesenchymal stem cell proliferation.

LTBP3

GO:1902463

BP

protein localization to cell leading edge

A process in which a protein is transported to, or maintained in, a location within a cell leading edge.

CORO1B

GO:1902474

BP

positive regulation of protein localization to synapse

Any process that activates or increases the frequency, rate or extent of protein localization to synapse.

WNT5A, NLGN1

GO:1902475

BP

L-alpha-amino acid transmembrane transport

The directed movement of L-alpha-amino acid across a membrane.

SLC7A5, SLC7A6, SLC7A8, SLC7A7

GO:1902476

BP

chloride transmembrane transport

The directed movement of chloride across a membrane.

FXYD1, CLIC1, BEST1, CLIC3, SLC4A2, CFTR, GABRA5, SLC1A4, GLRB, SLC26A2, CLCN3, CLCN4, CLCN5, CLCN6, CLCN7, CLCNKA, CLCNKB, SLC12A2, CLCA4, ANO6, SLC26A11, BEST3, CLIC6, SLC26A1, TTYH1, ANO2, CLIC5, PCYOX1

GO:1902480

BP

protein localization to mitotic spindle

A process in which a protein is transported to, or maintained in, a location within a mitotic spindle.

FAM83D

GO:1902499

BP

positive regulation of protein autoubiquitination

Any process that activates or increases the frequency, rate or extent of protein autoubiquitination.

MTA1

GO:1902510

BP

regulation of apoptotic DNA fragmentation

Any process that modulates the frequency, rate or extent of apoptotic DNA fragmentation.

AIFM1

GO:1902511

BP

negative regulation of apoptotic DNA fragmentation

Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic DNA fragmentation.

DFFA

GO:1902512

BP

positive regulation of apoptotic DNA fragmentation

Any process that activates or increases the frequency, rate or extent of apoptotic DNA fragmentation.

HSF1, BAX

GO:1902513

BP

regulation of organelle transport along microtubule

Any process that modulates the frequency, rate or extent of organelle transport along microtubule.

LAMP1, NEFH

GO:1902514

BP

regulation of calcium ion transmembrane transport via high voltage-gated calcium channel

Any process that modulates the frequency, rate or extent of generation of calcium ion transmembrane transport via high voltage-gated calcium channel.

CAMK2D

GO:1902523

BP

positive regulation of protein K63-linked ubiquitination

Any process that activates or increases the frequency, rate or extent of protein K63-linked ubiquitination.

PTPN22

GO:1902524

BP

positive regulation of protein K48-linked ubiquitination

Any process that activates or increases the frequency, rate or extent of protein K48-linked ubiquitination.

NMI

GO:1902525

BP

regulation of protein monoubiquitination

Any process that modulates the frequency, rate or extent of protein monoubiquitination.

WDR48

GO:1902530

BP

positive regulation of protein linear polyubiquitination

Any process that activates or increases the frequency, rate or extent of protein linear polyubiquitination.

PARK2, XIAP

GO:1902532

BP

negative regulation of intracellular signal transduction

Any process that stops, prevents or reduces the frequency, rate or extent of intracellular signal transduction.

LYN, DDIT4

GO:1902533

BP

positive regulation of intracellular signal transduction

Any process that activates or increases the frequency, rate or extent of intracellular signal transduction.

TNFSF11, TEK, NLGN1, PRKD2

GO:1902548

BP

negative regulation of cellular response to vascular endothelial growth factor stimulus

Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to vascular endothelial growth factor stimulus.

ADAMTS12

GO:1902583

BP

multi-organism intracellular transport

An intracellular transport which involves another organism.

RAB7A

GO:1902598

BP

creatine transmembrane transport

The directed movement of creatine across a membrane.

SLC6A8, SLC16A12

GO:1902600

BP

hydrogen ion transmembrane transport

The directed movement of hydrogen ion (proton) across a membrane.

UQCRHL, NDUFA4, UQCRQ, UQCR11, ATP6V1G1, ATP6V1G2, CYB5A, UQCRH, COX6C, COX6A1, COX6B1, UQCRB, COX7C, COX5A, COX7B, UQCRC1, UQCRFS1, SLC11A2, TMCO3, SLC36A1, COX7B2, SLC9A6, SLC47A1, SLC46A1, NMES1, SLC9A2, UQCR10, COX11

GO:1902603

BP

carnitine transmembrane transport

The directed movement of carnitine across a membrane.

SLC22A5

GO:1902605

BP

heterotrimeric G-protein complex assembly

The aggregation, arrangement and bonding together of a set of components to form a heterotrimeric G-protein complex.

PDCL

GO:1902608

BP

positive regulation of large conductance calcium-activated potassium channel activity

Any process that activates or increases the frequency, rate or extent of large conductance calcium-activated potassium channel activity.

GAL

GO:1902613

BP

negative regulation of anti-Mullerian hormone signaling pathway

Any process that stops, prevents or reduces the frequency, rate or extent of anti-Mullerian hormone signaling pathway.

AMHR2, DKK3

GO:1902617

BP

response to fluoride

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluoride stimulus.

PON1, FOXO1

GO:1902618

BP

cellular response to fluoride

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluoride stimulus.

COL1A1

GO:1902622

BP

regulation of neutrophil migration

Any process that modulates the frequency, rate or extent of neutrophil migration.

RAC2

GO:1902626

BP

assembly of large subunit precursor of preribosome

The aggregation, arrangement and bonding together of a set of components to form the large subunit precursor of the preribosome.

EIF6, RPL24

GO:1902661

BP

positive regulation of glucose mediated signaling pathway

Any process that activates or increases the frequency, rate or extent of glucose mediated signaling pathway.

SMARCA4

GO:1902679

BP

negative regulation of RNA biosynthetic process

Any process that stops, prevents or reduces the frequency, rate or extent of RNA biosynthetic process.

RGN

GO:1902685

BP

positive regulation of receptor localization to synapse

Any process that activates or increases the frequency, rate or extent of receptor localization to synapse.

STX7

GO:1902714

BP

negative regulation of interferon-gamma secretion

Any process that stops, prevents or reduces the frequency, rate or extent of interferon-gamma secretion.

NR1H4

GO:1902715

BP

positive regulation of interferon-gamma secretion

Any process that activates or increases the frequency, rate or extent of interferon-gamma secretion.

CD244, PTPN22

GO:1902722

BP

positive regulation of prolactin secretion

Any process that activates or increases the frequency, rate or extent of prolactin secretion.

EGFR, ABAT

GO:1902723

BP

negative regulation of skeletal muscle satellite cell proliferation

Any process that stops, prevents or reduces the frequency, rate or extent of satellite cell proliferation.

MSTN

GO:1902725

BP

negative regulation of satellite cell differentiation

Any process that stops, prevents or reduces the frequency, rate or extent of satellite cell differentiation.

MSTN

GO:1902728

BP

positive regulation of growth factor dependent skeletal muscle satellite cell proliferation

Any process that activates or increases the frequency, rate or extent of satellite cell proliferation; dependent on specific growth factor activity such as fibroblast growth factors and transforming growth factor beta.

JAK2, STAT3

GO:1902731

BP

negative regulation of chondrocyte proliferation

Any process that stops, prevents, or reduces the frequency, rate or extent of the multiplication or reproduction of chondrocytes by cell division, resulting in the expansion of their population. A chondrocyte is a polymorphic cell that forms cartilage.

BMPR2

GO:1902742

BP

apoptotic process involved in development

Any apoptotic process that is involved in anatomical structure development.

ZPR1

GO:1902745

BP

positive regulation of lamellipodium organization

Any process that activates or increases the frequency, rate or extent of lamellipodium organization.

LRRC16A

GO:1902749

BP

regulation of cell cycle G2/M phase transition

Any process that modulates the frequency, rate or extent of cell cycle G2/M phase transition.

TP53, PLK1, NEK10, GTSE1

GO:1902750

BP

negative regulation of cell cycle G2/M phase transition

Any process that stops, prevents or reduces the frequency, rate or extent of cell cycle G2/M phase transition.

H2AFY