GO ID |
Ontology |
GO Term |
Term Definition |
Proteins |
GO:0060972
|
BP
|
left/right pattern formation
|
The pattern specification process that results in the subdivision of the left/right axis in space to define an area or volume in which specific patterns of cell differentiation will take place or in which cells interpret a specific environment.
|
CITED2
|
GO:0060973
|
BP
|
cell migration involved in heart development
|
The orderly movement of a cell from one site to another that will contribute to the progression of the heart over time, from its initial formation, to the mature organ.
|
BVES,
NDRG4
|
GO:0060976
|
BP
|
coronary vasculature development
|
The process whose specific outcome is the progression of the blood vessels of the heart over time, from its formation to the mature structure.
|
SMAD6,
BMP4,
VEGFB,
NDST1,
AP2B1,
LRP2,
PTK7,
LTBP1,
TAB1,
PCSK5,
PRICKLE1,
DCTN5,
ADAMTS6,
SUFU,
PLXND1
|
GO:0060978
|
BP
|
angiogenesis involved in coronary vascular morphogenesis
|
Blood vessel formation in the heart when new vessels emerge from the proliferation of pre-existing blood vessels.
|
NRP1,
TGFBR1
|
GO:0060979
|
BP
|
vasculogenesis involved in coronary vascular morphogenesis
|
The differentiation of endothelial cells from progenitor cells that contributes to blood vessel development in the heart, and the de novo formation of blood vessels and tubes.
|
NOTCH1,
TGFBR3
|
GO:0060981
|
BP
|
cell migration involved in coronary angiogenesis
|
The orderly movement of a cell from one site to another that will contribute to the formation of new blood vessels in the heart from pre-existing blood vessels.
|
PDGFRB
|
GO:0060982
|
BP
|
coronary artery morphogenesis
|
The process in which the anatomical structures of coronary arteries are generated and organized. Coronary arteries are blood vessels that transport blood to the heart muscle.
|
NRP1,
TBX1,
VEGFA,
TGFBR1,
NOTCH1
|
GO:0060988
|
BP
|
lipid tube assembly
|
The aggregation, arrangement and bonding together of a set of macromolecules to form a macromolecular complex that contains a tube of lipid surrounded by a protein coat involved in membrane shaping of vesicle membranes as they fuse or undergo fission.
|
BIN1,
SNX9
|
GO:0060992
|
BP
|
response to fungicide
|
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fungicide stimulus. Fungicides are chemicals used to kill fungi.
|
KDM1A,
SRD5A1,
STAR,
KDM5B
|
GO:0060993
|
BP
|
kidney morphogenesis
|
Morphogenesis of a kidney. A kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine.
|
PRKX,
SOX4,
NPHP3
|
GO:0060996
|
BP
|
dendritic spine development
|
The process whose specific outcome is the progression of the dendritic spine over time, from its formation to the mature structure. A dendritic spine is a protrusion from a dendrite and a specialized subcellular compartment involved in synaptic transmission.
|
UBA6,
ACSL4,
ARF4,
EPHB2,
EPHB1,
PAK2,
SLC9A6
|
GO:0060997
|
BP
|
dendritic spine morphogenesis
|
The process in which the anatomical structures of a dendritic spine are generated and organized. A dendritic spine is a protrusion from a dendrite and a specialized subcellular compartment involved in synaptic transmission.
|
PAK3,
EPHB2,
EPHB1,
PTEN,
DLG4,
HDAC6
|
GO:0060998
|
BP
|
regulation of dendritic spine development
|
Any process that modulates the rate, frequency, or extent of dendritic spine development, the process whose specific outcome is the progression of the dendritic spine over time, from its formation to the mature structure.
|
MEF2C,
FMR1,
SDK1,
CPEB3
|
GO:0060999
|
BP
|
positive regulation of dendritic spine development
|
Any process that increases the rate, frequency, or extent of dendritic spine development, the process whose specific outcome is the progression of the dendritic spine over time, from its formation to the mature structure.
|
APOE,
PSEN1,
ARF1,
NRG1,
FMR1,
CAMK1,
NLGN1,
CPEB3,
LLPH
|
GO:0061000
|
BP
|
negative regulation of dendritic spine development
|
Any process that decreases the rate, frequency, or extent of dendritic spine development, the process whose specific outcome is the progression of the dendritic spine over time, from its formation to the mature structure.
|
HDAC2,
PLK2,
ASAP1
|
GO:0061001
|
BP
|
regulation of dendritic spine morphogenesis
|
Any process that modulates the rate, frequency, or extent of dendritic spine morphogenesis, the process in which the anatomical structures of a dendritic spine are generated and organized. A dendritic spine is a protrusion from a dendrite and a specialized subcellular compartment involved in synaptic transmission.
|
CFL1,
EPHA4,
CDK5,
PDLIM5
|
GO:0061002
|
BP
|
negative regulation of dendritic spine morphogenesis
|
Any process that decreases the rate, frequency, or extent of dendritic spine morphogenesis, the process in which the anatomical structures of a dendritic spine are generated and organized. A dendritic spine is a protrusion from a dendrite and a specialized subcellular compartment involved in synaptic transmission.
|
EFNA1,
PTEN,
NLGN1
|
GO:0061003
|
BP
|
positive regulation of dendritic spine morphogenesis
|
Any process that modulates the rate, frequency, or extent of dendritic spine morphogenesis, the process in which the anatomical structures of a dendritic spine are generated and organized. A dendritic spine is a protrusion from a dendrite and a specialized subcellular compartment involved in synaptic transmission.
|
PAK3,
ITPKA,
TIAM1,
CAPRIN1
|
GO:0061005
|
BP
|
cell differentiation involved in kidney development
|
The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the kidney as it progresses from its formation to the mature state.
|
GLI3,
PTCH1
|
GO:0061009
|
BP
|
common bile duct development
|
The progression of the common bile duct over time, from its formation to the mature structure. The common bile duct is formed from the joining of the common hepatic duct running from the liver, and the cystic duct running from the gall bladder. The common bile duct transports bile from the liver and gall bladder to the intestine.
|
HES1,
SOX17,
MKS1
|
GO:0061010
|
BP
|
gall bladder development
|
The progression of the gall bladder over time, from its initial formation to the mature structure. The gall bladder is a cavitated organ that stores bile.
|
HHEX,
NIPBL,
SOX17
|
GO:0061011
|
BP
|
hepatic duct development
|
The progression of the hepatic duct over time, from its formation to the mature structure. The hepatic duct is the duct that leads from the liver to the common bile duct.
|
HHEX
|
GO:0061014
|
BP
|
positive regulation of mRNA catabolic process
|
Any process that increases the rate, frequency, or extent of a mRNA catabolic process, the chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage.
|
CNOT1,
HNRNPR,
PNPT1,
KHSRP,
CNOT7
|
GO:0061017
|
BP
|
hepatoblast differentiation
|
The process in which a relatively unspecialized cell acquires specialized features of a hepatoblast. A hepatoblast is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into hepatocytes and cholangiocytes.
|
HHEX
|
GO:0061024
|
BP
|
membrane organization
|
A process which results in the assembly, arrangement of constituent parts, or disassembly of a membrane. A membrane is a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.
|
GNPAT,
TBC1D4,
PMP2,
RALA,
YWHAB,
SFN,
PRKCI,
YWHAE,
YWHAZ,
YWHAH,
CLN3,
DHCR24,
SGCB,
CCDC88A,
LPCAT2,
SGCD,
SGCZ,
CHP1,
LNPEP
|
GO:0061025
|
BP
|
membrane fusion
|
The membrane organization process that joins two lipid bilayers to form a single membrane.
|
SNAP23,
GOSR2,
STX11,
SNAP29,
VAMP2,
RABEP1,
VAMP3,
HACE1,
CHP1,
NAPB,
BET1L,
VAPA,
VTI1B,
BLOC1S6,
NSFL1C
|
GO:0061026
|
BP
|
cardiac muscle tissue regeneration
|
The regrowth of cardiac muscle tissue to repair injured or damaged muscle fibers in the postnatal stage.
|
ERBB4
|
GO:0061028
|
BP
|
establishment of endothelial barrier
|
The establishment of a barrier between endothelial cell layers, such as those in the brain, lung or intestine, to exert specific and selective control over the passage of water and solutes, thus allowing formation and maintenance of compartments that differ in fluid and solute composition.
|
ICAM1,
EZR,
RDX,
F2RL1,
RAP1A,
PDE4D,
RAPGEF1,
MYADM
|
GO:0061029
|
BP
|
eyelid development in camera-type eye
|
The progression of the eyelid in a camera-type eye from its formation to the mature state. The eyelid is a membranous cover that helps protect and lubricate the eye.
|
EGFR,
JUN,
INHBA,
SOS1,
HDAC1,
TWIST1,
HDAC2
|
GO:0061030
|
BP
|
epithelial cell differentiation involved in mammary gland alveolus development
|
The process in which a relatively unspecialized epithelial cell becomes a more specialized epithelial cell of the mammary gland alveolus.
|
ID2,
HIF1A
|
GO:0061031
|
BP
|
endodermal digestive tract morphogenesis
|
The process in which the anatomical structures of the endodermal digestive tract are generated and organized. The endodermal digestive tract includes those portions of the digestive tract that are derived from endoderm.
|
ID2,
PITX2,
SOX17
|
GO:0061032
|
BP
|
visceral serous pericardium development
|
The progression of the visceral serous pericardium from its formation to the mature structure. The visceral serous pericardium is the inner layer of the pericardium.
|
WT1
|
GO:0061033
|
BP
|
secretion by lung epithelial cell involved in lung growth
|
The controlled release of liquid by a lung epithelial cell that contributes to an increase in size of the lung as part of its development.
|
FGF7
|
GO:0061034
|
BP
|
olfactory bulb mitral cell layer development
|
The progression of the olfactory bulb mitral cell layer over time from its initial formation until its mature state. The mitral cell layer is composed of pyramidal neurons whose cell bodies are located between the granule cell layer and the plexiform layer.
|
OGDH
|
GO:0061035
|
BP
|
regulation of cartilage development
|
Any process that modulates the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate.
|
TGFB1
|
GO:0061036
|
BP
|
positive regulation of cartilage development
|
Any process that increases the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate.
|
CYR61,
BMP10,
BMP2,
BMP4,
BMP1,
SOX6,
WNT5A,
SOX9,
ZBTB16,
BMPR2,
SMAD1
|
GO:0061037
|
BP
|
negative regulation of cartilage development
|
Any process that decreases the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate.
|
LEP,
TGFB2
|
GO:0061038
|
BP
|
uterus morphogenesis
|
The process in which anatomical structures of the uterus are generated and organized.
|
NIPBL,
KDM5B
|
GO:0061040
|
BP
|
female gonad morphogenesis
|
The process in which a female gonad is generated and organized.
|
SMAD4
|
GO:0061041
|
BP
|
regulation of wound healing
|
Any process that modulates the rate, frequency, or extent of the series of events that restore integrity to a damaged tissue, following an injury.
|
PLAU,
SRSF6,
TNFRSF12A
|
GO:0061042
|
BP
|
vascular wound healing
|
Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to damaged vasculature.
|
MCAM,
ADIPOR2,
NDNF,
HPSE
|
GO:0061043
|
BP
|
regulation of vascular wound healing
|
Any process that modulates the rate, frequency, or extent of blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to damaged vasculature.
|
TNFAIP3
|
GO:0061044
|
BP
|
negative regulation of vascular wound healing
|
Any process that decreases the rate, frequency, or extent of blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to damaged vasculature.
|
SERPINE1
|
GO:0061045
|
BP
|
negative regulation of wound healing
|
Any process that decreases the rate, frequency, or extent of the series of events that restore integrity to a damaged tissue, following an injury.
|
CASK,
APCS,
HMGCR,
SERPINE1,
FGF2,
GJA1,
SMAD3,
WFDC1
|
GO:0061046
|
BP
|
regulation of branching involved in lung morphogenesis
|
Any process that modulates the rate, frequency, or extent of the process in which a highly ordered sequence of patterning events generates the branched structures of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units.
|
SOX9
|
GO:0061047
|
BP
|
positive regulation of branching involved in lung morphogenesis
|
Any process that modulates the rate, frequency, or extent of the process in which a highly ordered sequence of patterning events generates the branched structures of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units.
|
BMP4
|
GO:0061048
|
BP
|
negative regulation of branching involved in lung morphogenesis
|
Any process that decreases the rate, frequency, or extent of the process in which a highly ordered sequence of patterning events generates the branched structures of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units.
|
TNF
|
GO:0061049
|
BP
|
cell growth involved in cardiac muscle cell development
|
The growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state.
|
SORBS2,
AGT,
GATA4,
AGTR2,
CAMK2D,
PDLIM5
|
GO:0061051
|
BP
|
positive regulation of cell growth involved in cardiac muscle cell development
|
Any process that increases the rate, frequency, or extent of the growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state.
|
IGF1,
EDN1,
HAMP,
AKAP6
|
GO:0061052
|
BP
|
negative regulation of cell growth involved in cardiac muscle cell development
|
Any process that decreases the rate, frequency, or extent of the growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state.
|
G6PD
|
GO:0061053
|
BP
|
somite development
|
The progression of a somite from its initial formation to the mature structure. Somites are mesodermal clusters that are arranged segmentally along the anterior posterior axis of an embryo.
|
MTHFD1,
MEOX1,
PPP2R3A,
PTCH1,
RBBP6
|
GO:0061056
|
BP
|
sclerotome development
|
The progression of the sclerotome over time, from its initial formation to the mature structure. The sclerotome is the portion of the somite that will give rise to a vertebra.
|
MEOX1
|
GO:0061061
|
BP
|
muscle structure development
|
The progression of a muscle structure over time, from its formation to its mature state. Muscle structures are contractile cells, tissues or organs that are found in multicellular organisms.
|
CAPN3,
RNF165
|
GO:0061072
|
BP
|
iris morphogenesis
|
The process in which the iris is generated and organized. The iris is an anatomical structure in the eye whose opening forms the pupil. The iris is responsible for controlling the diameter and size of the pupil and the amount of light reaching the retina.
|
WNT2,
HIF1A,
WNT2B,
PITX2,
HIPK2
|
GO:0061073
|
BP
|
ciliary body morphogenesis
|
The process in which the ciliary body generated and organized. The ciliary body is the circumferential tissue inside the eye composed of the ciliary muscle and ciliary processes.
|
JAG1
|
GO:0061074
|
BP
|
regulation of neural retina development
|
Any process that modulates the rate, frequency, or extent of neural retina development, the progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells.
|
DLL4
|
GO:0061077
|
BP
|
chaperone-mediated protein folding
|
The process of inhibiting aggregation and assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure that is dependent on interaction with a chaperone.
|
TOR1A,
CRTAP,
CLU,
PDIA4,
PPIB,
FKBP2,
CALR,
CANX,
FKBP3,
FKBP4,
PPID,
FKBP5,
FKBP10,
FKBP14,
FKBP11,
CHORDC1,
FKBP7
|
GO:0061078
|
BP
|
positive regulation of prostaglandin secretion involved in immune response
|
Any process that activates or increases the frequency, rate or extent of the regulated release of a prostaglandin from a cell and contributes to the immune response.
|
MIF
|
GO:0061081
|
BP
|
positive regulation of myeloid leukocyte cytokine production involved in immune response
|
Any process that modulates the rate, frequency, or extent of the production of a cytokine that contributes to the immune response.
|
MIF
|
GO:0061084
|
BP
|
negative regulation of protein refolding
|
Any process that decreases the rate, frequency, or extent of protein refolding. Protein refolding is the process carried out by a cell that restores the biological activity of an unfolded or misfolded protein, using helper proteins such as chaperones.
|
PDCL,
BAG5
|
GO:0061086
|
BP
|
negative regulation of histone H3-K27 methylation
|
Any process that decreases the rate, frequency, or extent of histone H3-K27 methylation. Histone H3-K27 methylation is the modification of histone H3 by addition of a methyl group to lysine at position 27 of the histone.
|
H2AFY,
SUPT6H,
MTF2
|
GO:0061087
|
BP
|
positive regulation of histone H3-K27 methylation
|
Any process that increases the rate, frequency, or extent of histone H3-K27 methylation. Histone H3-K27 methylation is the modification of histone H3 by addition of a methyl group to lysine at position 27 of the histone.
|
OGT,
PHF19,
MTF2
|
GO:0061088
|
BP
|
regulation of sequestering of zinc ion
|
Any process that modulates the rate, frequency, or extent of sequestering of zinc ion. Sequestering of zinc ion is the process of binding or confining zinc ions such that they are separated from other components of a biological system.
|
AP3D1,
SLC30A8,
SLC30A1
|
GO:0061097
|
BP
|
regulation of protein tyrosine kinase activity
|
Any process that modulates the rate, frequency, or extent of protein tyrosine kinase activity.
|
RAP2B
|
GO:0061098
|
BP
|
positive regulation of protein tyrosine kinase activity
|
Any process that increases the rate, frequency, or extent of protein tyrosine kinase activity.
|
GREM1,
AGT,
PDGFB,
CSF1R,
ACE,
CCL5,
ERBB3,
CD24,
PAK2,
UNC119,
GAS6,
FAM150B,
ABI1,
AFAP1L2,
HSPH1,
GPRC5B,
GHRL
|
GO:0061099
|
BP
|
negative regulation of protein tyrosine kinase activity
|
Any process that decreases the rate, frequency, or extent of protein tyrosine kinase activity.
|
SH3BP5,
PTPN2,
RACK1,
CAV1,
HYAL2,
SH3BP5L
|
GO:0061100
|
BP
|
lung neuroendocrine cell differentiation
|
The process in which a relatively unspecialized cell acquires specialized features of a neuroendocrine cell of the lung epithelium.
|
ASCL1
|
GO:0061101
|
BP
|
neuroendocrine cell differentiation
|
The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a neuroendocrine cell. A neuroendocrine cell is a cell that receives input form a neuron which controls the secretion of an endocrine substance.
|
BCCIP
|
GO:0061102
|
BP
|
stomach neuroendocrine cell differentiation
|
The process in which a relatively unspecialized cell acquires specialized features of a neuroendocrine cell of the stomach epithelium.
|
ASCL1
|
GO:0061103
|
BP
|
carotid body glomus cell differentiation
|
The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a glomus cell of the carotid body. The carotid body is a specialized chemosensory organ that helps respond to hypoxia.
|
ASCL1
|
GO:0061104
|
BP
|
adrenal chromaffin cell differentiation
|
The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of an adrenal chromaffin cell. An adrenal chromaffin cell is a neuroendocrine cell that stores epinephrine secretory vesicles.
|
ASCL1,
INSM1
|
GO:0061106
|
BP
|
negative regulation of stomach neuroendocrine cell differentiation
|
Any process that decreases the rate, frequency or extent of the differentiation of a neuroendocrine cell in the stomach.
|
HES1
|
GO:0061108
|
BP
|
seminal vesicle epithelium development
|
The progression of the seminal vesicle epithelium over time, from its formation to the mature structure.
|
SERPINE2
|
GO:0061113
|
BP
|
pancreas morphogenesis
|
Morphogenesis of the pancreas. Morphogenesis is the process in which anatomical structures are generated and organized.
|
NR5A2
|
GO:0061114
|
BP
|
branching involved in pancreas morphogenesis
|
The process in which the branches of the pancreas are generated and organized.
|
PROX1
|
GO:0061136
|
BP
|
regulation of proteasomal protein catabolic process
|
Any process that modulates the rate, frequency, or extent of the chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds that is mediated by the proteasome.
|
GPX1,
PRKACA,
PSME3,
TMF1,
PKD1,
RHBDF1,
PINK1,
NUDT15,
BTRC,
UCHL5
|
GO:0061138
|
BP
|
morphogenesis of a branching epithelium
|
The process in which the anatomical structures of a branched epithelium are generated and organized.
|
SOX9,
SOX8
|
GO:0061141
|
BP
|
lung ciliated cell differentiation
|
The process in which a relatively unspecialized cell acquires specialized features of a lung ciliated cell. A lung ciliated cell is a specialized lung epithelial cell that contains cilia for moving substances released from lung secretory cells.
|
NFIB
|
GO:0061145
|
BP
|
lung smooth muscle development
|
The process whose specific outcome is the progression of smooth muscle in the lung over time, from its formation to the mature structure.
|
SOX9
|
GO:0061149
|
BP
|
BMP signaling pathway involved in ureter morphogenesis
|
A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to the shaping of the ureter. The ureter is a tube that extends from the kidney to the bladder.
|
BMP4
|
GO:0061151
|
BP
|
BMP signaling pathway involved in renal system segmentation
|
A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to the segmentation of the renal system.
|
BMP4
|
GO:0061154
|
BP
|
endothelial tube morphogenesis
|
The process in which the anatomical structures of a tube are generated and organized from an endothelium. Endothelium refers to the layer of cells lining blood vessels, lymphatics, the heart, and serous cavities, and is derived from bone marrow or mesoderm. Corneal endothelium is a special case, derived from neural crest cells.
|
CTNNB1,
RHOB,
CCM2,
PRKD2
|
GO:0061155
|
BP
|
pulmonary artery endothelial tube morphogenesis
|
The process in which the anatomical structures of a tube are generated and organized from the pulmonary artery endothelium. An pulmonary artery endothelium is an epithelium that lines the pulmonary artery.
|
BMP4
|
GO:0061156
|
BP
|
pulmonary artery morphogenesis
|
The process in which the anatomical structures of the pulmonary artery are generated and organized. The pulmonary artery is the artery that carries blood from the heart to the lungs.
|
JAG1
|
GO:0061157
|
BP
|
mRNA destabilization
|
Any process that decreases the stability of an mRNA molecule, making it more vulnerable to degradative processes. Messenger RNA is the intermediate molecule between DNA and protein. It includes UTR and coding sequences. It does not contain introns.
|
HNRNPR,
PUM1,
MEX3D,
METTL14
|
GO:0061158
|
BP
|
3'-UTR-mediated mRNA destabilization
|
An mRNA destabilization process in which one or more RNA-binding proteins associate with the 3'-untranslated region (UTR) of an mRNA.
|
ZC3H12D,
ZFP36,
ZFP36L2,
ZFP36L1,
HNRNPD,
CPEB3,
KHSRP,
QKI
|
GO:0061162
|
BP
|
establishment of monopolar cell polarity
|
The specification and formation of monopolar intracellular organization or cell growth patterns. Monopolar cell organization is directional organization along an axis.
|
MAP1B,
GBF1
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GO:0061178
|
BP
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regulation of insulin secretion involved in cellular response to glucose stimulus
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Any process that modulates the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose.
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LRP5,
NR1D1,
EFNA5,
EPHA5,
CDK16,
TIAM1,
NR1H4,
SYBU,
NRXN1
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GO:0061179
|
BP
|
negative regulation of insulin secretion involved in cellular response to glucose stimulus
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Any process that decreases the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose.
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HMGCR,
UCP2,
NDUFAF2,
ENY2
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GO:0061180
|
BP
|
mammary gland epithelium development
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The process whose specific outcome is the progression of the mammary gland epithelium over time, from its formation to the mature structure. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk.
|
JAK2,
WNT2,
WNT3
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GO:0061182
|
BP
|
negative regulation of chondrocyte development
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Any process that decreases the rate, frequency, or extent of the process whose specific outcome is the progression of a chondrocyte over time, from its commitment to its mature state. Chondrocyte development does not include the steps involved in committing a chondroblast to a chondrocyte fate.
|
FAM101A,
FAM101B
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GO:0061198
|
BP
|
fungiform papilla formation
|
The developmental process pertaining to the initial formation of a spongiform papilla from unspecified parts. The fungiform papilla is a mushroom-shaped papilla of the tongue.
|
CTNNB1,
HDAC1,
HDAC2
|
GO:0061290
|
BP
|
canonical Wnt signaling pathway involved in metanephric kidney development
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The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that contribute to the progression of the metanephric kidney over time. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes.
|
LGR4
|
GO:0061298
|
BP
|
retina vasculature development in camera-type eye
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The process whose specific outcome is the progression of the vasculature of the retina over time, from its formation to the mature structure.
|
PDGFRB,
PDGFRA,
ACVR2B,
BMPR2,
HIF1A
|
GO:0061299
|
BP
|
retina vasculature morphogenesis in camera-type eye
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The process in which the vasculature of the retina is generated and organized.
|
NRP1,
NDP,
RHOJ,
FZD4
|
GO:0061301
|
BP
|
cerebellum vasculature morphogenesis
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The process in which the vasculature of the cerebellum is generated and organized.
|
FZD4
|
GO:0061302
|
BP
|
smooth muscle cell-matrix adhesion
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The binding of a smooth muscle cell to the extracellular matrix via adhesion molecules.
|
VTN,
DDR1
|
GO:0061303
|
BP
|
cornea development in camera-type eye
|
The progression of the cornea over time, from its formation to the mature structure. The cornea is the transparent structure that covers the anterior of the eye.
|
WNT2B,
WNT6
|
GO:0061304
|
BP
|
retinal blood vessel morphogenesis
|
The process whose specific outcome is the progression of a blood vessel of the retina over time, from its formation to the mature structure.
|
LRP5,
CYP1B1,
FZD4
|
GO:0061308
|
BP
|
cardiac neural crest cell development involved in heart development
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The process aimed at the progression of a cardiac neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell that contributes to the development of the heart.
|
MAPK3,
MAPK1
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