|
GO:0070125
|
BP
|
mitochondrial translational elongation
|
The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis in a mitochondrion.
|
MRPS12,
MRPS14,
MRPL33,
TSFM,
MRPL19,
DAP3,
MRPL12,
MRPS25,
MRPS10,
MRPS5,
MRPS36,
MRPS21,
MRPS34,
ICT1,
MRPL23,
MRPL51,
MRPL54,
MRPL14,
MRPL21,
MRPL55,
MRPL52,
MRPL41,
MRPL50,
GADD45GIP1,
MRPL30,
MRPS31,
CHCHD1,
MRPL38,
PTCD3,
MRPL48,
GFM1,
MRPL34,
MRPL32,
MRPL4,
MRPL1,
MRPS26,
MRPL37,
MRPL44,
MRPL47,
MRPL40,
MRPL17,
MRPS18A,
AURKAIP1,
MRPL16,
MRPL35,
MRPL15,
MRPL36,
MRPS28,
MRPS18B,
MRPL42
|
|
GO:0070126
|
BP
|
mitochondrial translational termination
|
The process resulting in the release of a polypeptide chain from the ribosome in a mitochondrion, usually in response to a termination codon (note that mitochondria use variants of the universal genetic code that differ between different taxa).
|
MRPS12,
MRPS14,
MRPL33,
MRPL19,
DAP3,
MRPL12,
MRPS25,
MRPS10,
MRPS5,
MRPS36,
MRPS21,
MRPS34,
ICT1,
MRPL23,
MRPL51,
MRPL54,
MRPL14,
MRPL21,
MRPL55,
MRPL52,
MRPL41,
MRPL50,
GADD45GIP1,
MRPL30,
MRPS31,
CHCHD1,
MRPL38,
PTCD3,
MRPL48,
MRPL34,
MRPL32,
MRPL4,
MRPL1,
MRPS26,
MRPL37,
C12orf65,
MRPL44,
MRPL47,
MRPL40,
MRPL17,
MRPS18A,
AURKAIP1,
MRPL16,
MRPL35,
MRPL15,
MRPL36,
MRPS28,
MRPS18B,
MRPL42
|
|
GO:0070127
|
BP
|
tRNA aminoacylation for mitochondrial protein translation
|
The synthesis of aminoacyl tRNA by the formation of an ester bond between the 3'-hydroxyl group of the most 3' adenosine of the tRNA, to be used in ribosome-mediated polypeptide synthesis in a mitochondrion.
|
EARS2
|
|
GO:0070129
|
BP
|
regulation of mitochondrial translation
|
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA in a mitochondrion.
|
LRPPRC,
MTG1,
MTG2
|
|
GO:0070130
|
BP
|
negative regulation of mitochondrial translation
|
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA in a mitochondrion.
|
MALSU1
|
|
GO:0070131
|
BP
|
positive regulation of mitochondrial translation
|
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA in a mitochondrion.
|
C1QBP,
UQCC2,
COA3
|
|
GO:0070141
|
BP
|
response to UV-A
|
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-A radiation stimulus. UV-A radiation (UV-A light) spans the wavelengths 315 to 400 nm.
|
EGFR,
AKT1
|
|
GO:0070142
|
BP
|
synaptic vesicle budding
|
Evagination of a membrane to form a synaptic vesicle.
|
ARF1
|
|
GO:0070164
|
BP
|
negative regulation of adiponectin secretion
|
Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of adiponectin from a cell.
|
RAB11FIP3,
IL1B,
RAB11FIP1
|
|
GO:0070165
|
BP
|
positive regulation of adiponectin secretion
|
Any process that activates or increases the frequency, rate or extent of the regulated release of adiponectin from a cell.
|
C1QTNF3
|
|
GO:0070166
|
BP
|
enamel mineralization
|
The process in which calcium salts, mainly carbonated hydroxyapatite, are deposited in tooth enamel.
|
TBX1,
PPARA,
FOXO1,
NECTIN1,
WDR72,
FAM20C
|
|
GO:0070168
|
BP
|
negative regulation of biomineral tissue development
|
Any process that stops, prevents, or reduces the frequency, rate or extent of biomineral tissue development, the formation of hard tissues that consist mainly of inorganic compounds.
|
AHSG,
SOX9,
GAS6
|
|
GO:0070172
|
BP
|
positive regulation of tooth mineralization
|
Any process that activates or increases the frequency, rate or extent of tooth mineralization, the deposition of calcium salts in tooth structures.
|
WNT6
|
|
GO:0070189
|
BP
|
kynurenine metabolic process
|
The chemical reactions and pathways involving kynurenine, the amino acid 3-(2-aminobenzoyl)-alanine.
|
KMO
|
|
GO:0070192
|
BP
|
chromosome organization involved in meiotic cell cycle
|
A process of chromosome organization that is involved in a meiotic cell cycle.
|
RAD51C,
RAD51,
RAD50
|
|
GO:0070193
|
BP
|
synaptonemal complex organization
|
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a synaptonemal complex. A synaptonemal complex is a proteinaceous scaffold formed between homologous chromosomes during meiosis.
|
UBE2B
|
|
GO:0070194
|
BP
|
synaptonemal complex disassembly
|
The controlled breakdown of a synaptonemal complex.
|
PLK1
|
|
GO:0070198
|
BP
|
protein localization to chromosome, telomeric region
|
Any process in which a protein is transported to, or maintained at, the telomeric region of a chromosome.
|
TNKS,
ATRX,
ACD,
TNKS2
|
|
GO:0070200
|
BP
|
establishment of protein localization to telomere
|
The directed movement of a protein to a specific location in the telomeric region of a chromosome.
|
BRCA2,
ACD,
NABP2,
POT1
|
|
GO:0070201
|
BP
|
regulation of establishment of protein localization
|
Any process that modulates the frequency, rate or extent of the directed movement of a protein to a specific location.
|
WHSC1,
HDAC6
|
|
GO:0070202
|
BP
|
regulation of establishment of protein localization to chromosome
|
Any process that modulates the frequency, rate or extent of the directed movement of a protein to a specific location on a chromosome.
|
SPIDR
|
|
GO:0070206
|
BP
|
protein trimerization
|
The formation of a protein trimer, a macromolecular structure consisting of three noncovalently associated identical or nonidentical subunits.
|
TRIM22,
C1QTNF3,
TRIM34,
TRIM6,
TRIM4
|
|
GO:0070207
|
BP
|
protein homotrimerization
|
The formation of a protein homotrimer, a macromolecular structure consisting of three noncovalently associated identical subunits.
|
MGST1,
SKI,
MIF,
PNPT1,
SIGMAR1,
ATXN10
|
|
GO:0070208
|
BP
|
protein heterotrimerization
|
The formation of a protein heterotrimer, a macromolecular structure consisting of three noncovalently associated subunits, of which not all are identical.
|
WIZ,
COL1A1,
COL1A2,
COL6A1,
COL6A2,
NUP62,
GNB1,
ADIPOQ,
NUP58,
C1QTNF1
|
|
GO:0070212
|
BP
|
protein poly-ADP-ribosylation
|
The transfer of multiple ADP-ribose residues from NAD to a protein amino acid, forming a poly(ADP-ribose) chain.
|
TNKS,
PARP1
|
|
GO:0070213
|
BP
|
protein auto-ADP-ribosylation
|
The ADP-ribosylation by a protein of one or more of its own amino acid residues, or residues on an identical protein.
|
TNKS,
TNKS2
|
|
GO:0070221
|
BP
|
sulfide oxidation, using sulfide:quinone oxidoreductase
|
A sulfide oxidation process that proceeds via the reaction catalyzed by sulfide:quinone oxidoreductase.
|
ETHE1,
SUOX,
SLC25A10
|
|
GO:0070230
|
BP
|
positive regulation of lymphocyte apoptotic process
|
Any process that activates or increases the frequency, rate or extent of lymphocyte death by apoptotic process.
|
FAS
|
|
GO:0070231
|
BP
|
T cell apoptotic process
|
Any apoptotic process in a T cell, a type of lymphocyte whose defining characteristic is the expression of a T cell receptor complex.
|
BCL10,
RIPK1
|
|
GO:0070232
|
BP
|
regulation of T cell apoptotic process
|
Any process that modulates the occurrence or rate of T cell death by apoptotic process.
|
LGALS3,
JAK3
|
|
GO:0070233
|
BP
|
negative regulation of T cell apoptotic process
|
Any process that stops, prevents, or reduces the frequency, rate or extent of T cell death by apoptotic process.
|
CCL5,
CD27,
PRKCQ,
DOCK8,
SLC46A2
|
|
GO:0070234
|
BP
|
positive regulation of T cell apoptotic process
|
Any process that activates or increases the frequency, rate or extent of T cell death by apoptotic process.
|
CCL5,
LGALS13,
PRELID1
|
|
GO:0070236
|
BP
|
negative regulation of activation-induced cell death of T cells
|
Any process that stops, prevents, or reduces the frequency, rate or extent of activation-induced cell death of T cells.
|
FADD,
TSC22D3,
GPAM
|
|
GO:0070237
|
BP
|
positive regulation of activation-induced cell death of T cells
|
Any process that activates or increases the frequency, rate or extent of activation-induced cell death of T cells.
|
TGFB2
|
|
GO:0070242
|
BP
|
thymocyte apoptotic process
|
Any apoptotic process in a thymocyte, an immature T cell located in the thymus.
|
DFFA,
BCL2L11,
GLI3,
BAX
|
|
GO:0070244
|
BP
|
negative regulation of thymocyte apoptotic process
|
Any process that stops, prevents, or reduces the frequency, rate or extent of thymocyte death by apoptotic process.
|
ADA,
BMP4,
RAG1,
EFNA1,
JAK3,
HIF1A
|
|
GO:0070245
|
BP
|
positive regulation of thymocyte apoptotic process
|
Any process that activates or increases the frequency, rate or extent of thymocyte death by apoptotic process.
|
TP53,
WNT5A,
ADAM8
|
|
GO:0070252
|
BP
|
actin-mediated cell contraction
|
The actin filament-based process in which cytoplasmic actin filaments slide past one another resulting in contraction of all or part of the cell body.
|
EMP2,
PARVA
|
|
GO:0070253
|
BP
|
somatostatin secretion
|
The regulated release of somatostatin from secretory granules in the D cells of the pancreas.
|
CARTPT
|
|
GO:0070256
|
BP
|
negative regulation of mucus secretion
|
Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of mucus from a cell or a tissue.
|
ADA,
ADORA1
|
|
GO:0070257
|
BP
|
positive regulation of mucus secretion
|
Any process that activates or increases the frequency, rate or extent of the regulated release of mucus from a cell or a tissue.
|
SYTL2
|
|
GO:0070262
|
BP
|
peptidyl-serine dephosphorylation
|
The removal of phosphoric residues from peptidyl-O-phospho-L-serine to form peptidyl-serine.
|
PPP1R15A,
PPP2R1A
|
|
GO:0070266
|
BP
|
necroptotic process
|
A programmed necrotic cell death process which begins when a cell receives a signal (e.g. a ligand binding to a death receptor or to a Toll-like receptor), and proceeds through a series of biochemical events (signaling pathways), characterized by activation of receptor-interacting serine/threonine-protein kinase 1 and/or 3 (RIPK1/3, also called RIP1/3) and by critical dependence on mixed lineage kinase domain-like (MLKL), and which typically lead to common morphological features of necrotic cell death. The process ends when the cell has died. The process is divided into a signaling phase, and an execution phase, which is triggered by the former.
|
TLR4,
TLR3,
CD14,
PPIF,
RIPK1,
TRPM7,
CYLD
|
|
GO:0070268
|
BP
|
cornification
|
A type of programmed cell death that occurs in the epidermis, morphologically and biochemically distinct from apoptosis. It leads to the formation of corneocytes, i.e. dead keratinocytes containing an amalgam of specific proteins (e.g., keratin, loricrin, SPR and involucrin) and lipids (e.g., fatty acids and ceramides), which are necessary for the function of the cornified skin layer (mechanical resistance, elasticity, water repellence and structural stability).
|
CYP26B1
|
|
GO:0070269
|
BP
|
pyroptosis
|
A caspase-1-dependent cell death subroutine that is associated with the generation of pyrogenic mediators such as IL-1beta and IL-18.
|
CASP1
|
|
GO:0070278
|
BP
|
extracellular matrix constituent secretion
|
The controlled release of molecules that form the extracellular matrix, including carbohydrates and glycoproteins by a cell.
|
CTGF,
CREB3L1
|
|
GO:0070286
|
BP
|
axonemal dynein complex assembly
|
The aggregation, arrangement and bonding together of a set of components to form an axonemal dynein complex, a dynein complex found in eukaryotic cilia and flagella, in which the motor domain heads interact with adjacent microtubules to generate a sliding force which is converted to a bending motion.
|
CCDC103,
DRC1,
DNAAF2
|
|
GO:0070292
|
BP
|
N-acylphosphatidylethanolamine metabolic process
|
The chemical reactions and pathways involving N-acylphosphatidylethanolamines. An N-acylphosphatidylethanolamine is a phosphatidylethanolamine substituted at nitrogen by an acyl group.
|
HRASLS5
|
|
GO:0070293
|
BP
|
renal absorption
|
A renal system process in which water, ions, glucose and proteins are taken up from the collecting ducts, glomerulus and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures (e.g. protein absorption is observed in nephrocytes in Drosophila, see PMID:23264686).
|
AKR1C3,
HBB
|
|
GO:0070294
|
BP
|
renal sodium ion absorption
|
A renal system process in which sodium ions are taken up from the collecting ducts and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures.
|
KLHL3,
MAGED2
|
|
GO:0070295
|
BP
|
renal water absorption
|
A renal system process in which water is taken up from the collecting ducts and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures.
|
HYAL2,
AQP3,
HAS2
|
|
GO:0070296
|
BP
|
sarcoplasmic reticulum calcium ion transport
|
The directed movement of calcium ions (Ca2+) into, out of or within the sarcoplasmic reticulum.
|
ATP2A2,
ANK2,
RYR2
|
|
GO:0070301
|
BP
|
cellular response to hydrogen peroxide
|
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen peroxide (H2O2) stimulus.
|
KLF4,
AIFM1,
CST3,
ANXA1,
IL6,
CDK1,
PCNA,
ETS1,
AKR1B1,
TNFAIP3,
PPIF,
RHOB,
HSF1,
MDM2,
RELA,
PRKCD,
FOXO1,
BNIP3,
MAPK7,
EZH2,
FXN,
CYP1B1,
SETX,
NET1,
HDAC2,
MAP3K5,
PDGFD,
ECT2,
ZNF277,
OSER1,
IMPACT,
HDAC6,
ZNF580,
TRPC6,
KLF2
|
|
GO:0070304
|
BP
|
positive regulation of stress-activated protein kinase signaling cascade
|
Any process that activates or increases the frequency, rate or extent of signaling via the stress-activated protein kinase signaling cascade.
|
LYN
|
|
GO:0070306
|
BP
|
lens fiber cell differentiation
|
The process in which a relatively unspecialized cell acquires specialized features of a lens fiber cell, any of the elongated, tightly packed cells that make up the bulk of the mature lens in the camera-type eye. The cytoplasm of a lens fiber cell is devoid of most intracellular organelles including the cell nucleus, and contains primarily crystallins, a group of water-soluble proteins expressed in vary large quantities.
|
MAF,
TGFB1,
SKIL,
NF2,
SMAD3,
KDM5B,
FZR1,
SLC7A11
|
|
GO:0070307
|
BP
|
lens fiber cell development
|
The process whose specific outcome is the progression of a lens fiber cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a lens fiber cell fate. A lens fiber cell is any of the elongated, tightly packed cells that make up the bulk of the mature lens in a camera-type eye.
|
VIM,
TMOD1,
FRS2,
WNT5B
|
|
GO:0070309
|
BP
|
lens fiber cell morphogenesis
|
The process in which the structures of a lens fiber cell are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a lens fiber cell. A lens fiber cell is any of the elongated, tightly packed cells that make up the bulk of the mature lens in a camera-type eye.
|
PROX1
|
|
GO:0070314
|
BP
|
G1 to G0 transition
|
A cell cycle arrest process that results in arrest during G1 phase, whereupon the cell enters a specialized resting state known as G0 or quiescence.
|
CYP27B1,
PHGDH,
HRSP12,
EZH2
|
|
GO:0070315
|
BP
|
G1 to G0 transition involved in cell differentiation
|
A cell cycle arrest process that results in arrest during G1 phase, whereupon the cell enters G0 phase, in the context of cell differentiation.
|
CAPN3,
ZNF503
|
|
GO:0070317
|
BP
|
negative regulation of G0 to G1 transition
|
A cell cycle process that stops, prevents, or reduces the rate or extent of the transition from the G0 quiescent state to the G1 phase.
|
FOXO4,
PPP2R5B
|
|
GO:0070318
|
BP
|
positive regulation of G0 to G1 transition
|
A cell cycle process that activates or increases the rate or extent of the transition from the G0 quiescent state to the G1 phase.
|
SOX15,
CTGF,
RHNO1
|
|
GO:0070327
|
BP
|
thyroid hormone transport
|
The directed movement of thyroid hormone into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
SLC16A10
|
|
GO:0070328
|
BP
|
triglyceride homeostasis
|
Any process involved in the maintenance of an internal steady state of triglyceride within an organism or cell.
|
APOA1,
APOE,
APOC3,
LPL,
RORA,
SESN2,
NR1H3,
IL18,
APOA5,
SCARB1
|
|
GO:0070345
|
BP
|
negative regulation of fat cell proliferation
|
Any process that stops or decreases the rate or extent of fat cell proliferation.
|
E2F1,
TFDP1
|
|
GO:0070346
|
BP
|
positive regulation of fat cell proliferation
|
Any process that activates or increases the rate or extent of fat cell proliferation.
|
PID1
|
|
GO:0070350
|
BP
|
regulation of white fat cell proliferation
|
Any process that modulates the frequency, rate or extent of white fat cell proliferation.
|
FTO
|
|
GO:0070358
|
BP
|
actin polymerization-dependent cell motility
|
A process involved in the controlled movement of a bacterial cell powered by the continuous polymerization of actin at one pole of the cell.
|
EPS8,
JMY
|
|
GO:0070365
|
BP
|
hepatocyte differentiation
|
The process in which a relatively unspecialized cell acquires the specialized features of a hepatocyte. A hepatocyte is specialized epithelial cell that is organized into interconnected plates called lobules, and is the main structural component of the liver.
|
E2F8,
ANXA1,
CYP1A1,
ITGA2,
HHEX,
PROX1
|
|
GO:0070370
|
BP
|
cellular heat acclimation
|
Any process that increases heat tolerance of a cell in response to high temperatures.
|
HSPA1A,
HSPA1B
|
|
GO:0070371
|
BP
|
ERK1 and ERK2 cascade
|
An intracellular protein kinase cascade containing at least ERK1 or ERK2 (MAPKs), a MEK (a MAPKK) and a MAP3K. The cascade can also contain two additional tiers: the upstream MAP4K and the downstream MAP Kinase-activated kinase (MAPKAPK). The kinases in each tier phosphorylate and activate the kinases in the downstream tier to transmit a signal within a cell.
|
TNFSF11,
AGT,
IGF1,
ITGAV,
CTSH,
MT3,
MAPK3,
MAPK1,
OXTR,
PTGER4,
MAP2K2,
HTR2B,
ZFP36L2,
SOX9,
MAP2K1,
ZFP36L1,
IQGAP3
|
|
GO:0070372
|
BP
|
regulation of ERK1 and ERK2 cascade
|
Any process that modulates the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade.
|
CYR61,
FN1,
ERBB2,
LYN,
GSTP1,
RRAS,
FGFR2,
SYK,
EPHB1,
TIAM1,
NEK10,
FRS2,
FAM83D
|
|
GO:0070373
|
BP
|
negative regulation of ERK1 and ERK2 cascade
|
Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade.
|
TLR4,
ITGB1BP1,
KLF4,
SPRY2,
SPRY1,
LYN,
GSTP1,
LIF,
EZR,
PTPN2,
ATF3,
FBLN1,
DUSP1,
GBP1,
PHB,
TIMP3,
CSK,
DUSP3,
SYNJ2BP,
PTEN,
DLG1,
SMAD4,
RAPGEF1,
EIF3A,
ADIPOQ,
DUSP6,
CNKSR3,
FLCN,
RANBP9,
GPER1,
DUSP26,
SPRY4,
ERRFI1,
NDRG2
|
|
GO:0070374
|
BP
|
positive regulation of ERK1 and ERK2 cascade
|
Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade.
|
TLR4,
NRP1,
RIPK2,
SPRY2,
SEMA7A,
FGF18,
FGF19,
EGFR,
PDGFB,
GCG,
TNF,
FGA,
FGB,
FGG,
HMGCR,
PDGFA,
CD74,
NTRK1,
IL6,
ICAM1,
JUN,
CSF1R,
FGF2,
HMGB1,
PDGFRB,
CCL3,
BMP2,
BMP4,
CCL4,
CCL2,
CCL5,
MIF,
DRD2,
PLA2G2A,
ALOX15,
CD44,
NQO2,
PDGFRA,
CD36,
PRKCA,
C5AR1,
FGFR2,
FSHR,
F2R,
MT3,
MAPK3,
HTR2C,
CTGF,
S100A7,
GPR183,
PHB,
ADRA1A,
FLT4,
CHI3L1,
MAP2K2,
PLA2G5,
HTR2B,
F2RL1,
TIRAP,
PTEN,
RAP1A,
CCL20,
CCL8,
MAP2K1,
TEK,
PTPN11,
CAMK2D,
GAS6,
ERBB4,
ANGPT1,
NPY5R,
FAM150B,
DSTYK,
GCNT2,
BMPER,
PRKCDBP,
GPER1,
PHB2,
CIB1,
PRKD2,
PDGFD,
GLIPR2,
GAREM1,
TRPV4,
NOX4,
PDGFC,
DNAJC27,
NDRG4,
PYCARD,
PTPN22
|
|
GO:0070375
|
BP
|
ERK5 cascade
|
An intracellular protein kinase cascade containing at least ERK5 (also called BMK1; a MAPK), a MEK (a MAPKK) and a MAP3K. The cascade can also contain two additional tiers: the upstream MAP4K and the downstream MAP Kinase-activated kinase (MAPKAPK). The kinases in each tier phosphorylate and activate the kinases in the downstream tier to transmit a signal within a cell.
|
MEF2A,
MAP2K5
|
|
GO:0070377
|
BP
|
negative regulation of ERK5 cascade
|
Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the ERK5 cascade.
|
MAPK7
|
|
GO:0070378
|
BP
|
positive regulation of ERK5 cascade
|
Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the ERK5 cascade.
|
FAM150B
|
|
GO:0070383
|
BP
|
DNA cytosine deamination
|
The removal of an amino group from a cytosine residue in DNA, forming a uracil residue.
|
APOBEC3G
|
|
GO:0070384
|
BP
|
Harderian gland development
|
The process whose specific outcome is the progression of the Harderian gland over time, from its formation to the mature structure. The Harderian gland is an anterior orbital structure usually associated with the nictitating membrane, and produces and secretes a variety of substances to the eye, depending upon the species.
|
SOX9
|
|
GO:0070389
|
BP
|
chaperone cofactor-dependent protein refolding
|
The process of assisting in the restoration of the biological activity of an unfolded or misfolded protein, which is dependent on additional protein cofactors. This process occurs over one or several cycles of nucleotide hydrolysis-dependent binding and release.
|
DNAJB1,
PTGES3,
DNAJC7
|
|
GO:0070417
|
BP
|
cellular response to cold
|
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism.
|
FOXO1,
DNAJC3,
EIF2AK4
|
|
GO:0070423
|
BP
|
nucleotide-binding oligomerization domain containing signaling pathway
|
Any series of molecular signals generated as a consequence of binding to a nucleotide-binding oligomerization domain containing (NOD) protein.
|
IRAK2,
MAP3K7,
RIPK2,
UBC,
TNFAIP3,
IRAK1,
MAP2K6,
RPS27A,
UBA52,
UBE2V1,
CASP8,
TAB1,
TAB3,
ITCH,
CYLD
|
|
GO:0070424
|
BP
|
regulation of nucleotide-binding oligomerization domain containing signaling pathway
|
Any process that modulates the frequency, rate, or extent of a nucleotide-binding oligomerization domain containing (NOD) pathway.
|
XIAP,
BIRC3
|
|
GO:0070427
|
BP
|
nucleotide-binding oligomerization domain containing 1 signaling pathway
|
Any series of molecular signals generated as a consequence of binding to nucleotide-binding oligomerization domain containing 1 (NOD1).
|
RIPK2
|
|
GO:0070429
|
BP
|
negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway
|
Any process that stops, prevents, or reduces the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing 1 (NOD1) pathway.
|
TNFAIP3
|
|
GO:0070430
|
BP
|
positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway
|
Any process that activates or increases the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing 1 (NOD1) pathway.
|
TLR4
|
|
GO:0070431
|
BP
|
nucleotide-binding oligomerization domain containing 2 signaling pathway
|
Any series of molecular signals generated as a consequence of binding to nucleotide-binding oligomerization domain containing 2 (NOD2).
|
RIPK2,
RELA
|
|
GO:0070433
|
BP
|
negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway
|
Any process that stops, prevents, or reduces the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing 2 (NOD2) pathway.
|
TNFAIP3,
PTPN22
|
|
GO:0070434
|
BP
|
positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway
|
Any process that activates or increases the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing 2 (NOD2) pathway.
|
TLR4,
HSPA1A,
HSPA1B
|
|
GO:0070445
|
BP
|
regulation of oligodendrocyte progenitor proliferation
|
Any process that modulates the frequency, rate or extent of oligodendrocyte progenitor proliferation.
|
CDH2
|
|
GO:0070446
|
BP
|
negative regulation of oligodendrocyte progenitor proliferation
|
Any process that stops or decreases the rate or extent of oligodendrocyte progenitor proliferation.
|
SIRT2
|
|
GO:0070447
|
BP
|
positive regulation of oligodendrocyte progenitor proliferation
|
Any process that activates or increases the rate or extent of oligodendrocyte progenitor proliferation.
|
LYN
|
|
GO:0070458
|
BP
|
cellular detoxification of nitrogen compound
|
Any cellular process that reduces or removes the toxicity of nitrogenous compounds which are dangerous or toxic. This includes the aerobic conversion of toxic compounds to harmless substances.
|
GSTM1,
GSTM3,
GSTM2
|
|
GO:0070459
|
BP
|
prolactin secretion
|
The regulated release of prolactin, a peptide hormone that stimulates lactation, from secretory granules in the anterior pituitary.
|
ANXA1
|
|
GO:0070471
|
BP
|
uterine smooth muscle contraction
|
A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the uterus. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The uterus is a muscular organ of the female mammal for containing and usually for nourishing the young during development prior to birth.
|
AGT
|
|
GO:0070474
|
BP
|
positive regulation of uterine smooth muscle contraction
|
Any process that modulates the frequency, rate or extent of uterine smooth muscle contraction.
|
OXTR,
ABAT,
GPER1
|
|
GO:0070475
|
BP
|
rRNA base methylation
|
The addition of a methyl group to an atom in the nucleoside base portion of a nucleotide residue in an rRNA molecule.
|
METTL15,
NOP2,
METTL16,
EMG1
|
|
GO:0070481
|
BP
|
nuclear-transcribed mRNA catabolic process, non-stop decay
|
The chemical reactions and pathways resulting in the breakdown of the transcript body of a nuclear-transcribed mRNA that is lacking a stop codon.
|
PELO
|
|
GO:0070487
|
BP
|
monocyte aggregation
|
The adhesion of one monocyte to one or more other monocytes via adhesion molecules.
|
IL1B,
CD44
|
|
GO:0070488
|
BP
|
neutrophil aggregation
|
The adhesion of one neutrophil to one or more other neutrophils via adhesion molecules.
|
S100A8,
S100A9
|
|
GO:0070493
|
BP
|
thrombin receptor signaling pathway
|
The series of molecular signals generated as a consequence of a thrombin receptor binding to one of its physiological ligands.
|
HPGD,
F2R,
F2RL1,
IQGAP2
|