Search Geneontologies

Geneontologies

GO ID Ontology GO Term Term Definition Proteins

GO:0070495

BP

negative regulation of thrombin receptor signaling pathway

Any process that stops, prevents, or reduces the frequency, rate or extent of thrombin receptor protein signaling pathway activity. A thrombin receptor signaling pathway is the series of molecular signals generated as a consequence of a thrombin receptor binding to one of its physiological ligands.

SNCA

GO:0070498

BP

interleukin-1-mediated signaling pathway

A series of molecular signals initiated by the binding of interleukin-1 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.

IRAK2, RPS6KA5, IL1A, IL1R1, EGR1, MAPK3, IRAK1, PLCB1, IRAK3

GO:0070507

BP

regulation of microtubule cytoskeleton organization

Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins.

EPHA3, EFNA5, DIXDC1, PHLDB2, PHLDB1, KIF18A, CYLD, RASSF1, CAMSAP3

GO:0070508

BP

cholesterol import

The directed movement of cholesterol into a cell or organelle.

LDLR, APOA1, CD36, SCARB1, STARD4

GO:0070509

BP

calcium ion import

The directed movement of calcium ions into a cell or organelle.

CASK, CACNA1G, CDK5, MCUR1, TRPV4, SLC30A1

GO:0070512

BP

positive regulation of histone H4-K20 methylation

Any process that activates or increases the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 20 of histone H4.

BRCA1

GO:0070525

BP

tRNA threonylcarbamoyladenosine metabolic process

The chemical reactions and pathways involving tRNA threonylcarbamoyladenosine, a modified nucleoside found in some tRNA molecules.

TP53RK

GO:0070527

BP

platelet aggregation

The adhesion of one platelet to one or more other platelets via adhesion molecules.

CLIC1, FGA, FGB, FGG, HSPB1, ITGB3, PDGFRA, MYL12A, CSRP1, FLNA, MYL9, MYH9, PIK3CB, PIK3CG, ACTB, RAP2B, STXBP1, ACTG1, HBB, GNAS, TYRO3, ILK, GAS6, GNAS, SLC7A11, TLN1

GO:0070528

BP

protein kinase C signaling

A series of reactions, mediated by the intracellular serine/threonine kinase protein kinase C, which occurs as a result of a single trigger reaction or compound.

FLOT1, PDGFB, ZP3, HTR2B, ADGRG1

GO:0070534

BP

protein K63-linked ubiquitination

A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 63 of the ubiquitin monomers, is added to a protein. K63-linked ubiquitination does not target the substrate protein for degradation, but is involved in several pathways, notably as a signal to promote error-free DNA postreplication repair.

WWP2, PARK2, RNF8, UBE2B, UBE2V1, UBE2V2, UBE2S, RNF152, UBE2E3, ITCH, ZFP91, UBE2E2, RNF126, UBE2T, PRPF19, STUB1, UBE2D4

GO:0070535

BP

histone H2A K63-linked ubiquitination

A histone ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 63 of the ubiquitin monomers, is added to a lysine residue in histone H2A or the variant H2AX.

RNF8

GO:0070536

BP

protein K63-linked deubiquitination

A protein deubiquitination process in which a K63-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 63 of the ubiquitin monomers, is removed from a protein.

USP27X, TNFAIP3, BRCC3, ATXN3, FAM175B, OTUD1, OTUD7B, USP13, OTUB2, CYLD, ZRANB1, USP25, USP20

GO:0070537

BP

histone H2A K63-linked deubiquitination

A protein deubiquitination process in which a K63-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 63 of the ubiquitin monomers, is removed from a lysine residue in histone H2A or the variant H2AX.

BRCC3

GO:0070541

BP

response to platinum ion

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a platinum stimulus.

ALAD

GO:0070542

BP

response to fatty acid

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fatty acid stimulus.

GNPAT, TLR2, ASS1, FABP3, ALAD, CD36, PON1, CTGF, PTGS2, HMGCL, UCP2

GO:0070543

BP

response to linoleic acid

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a linoleic acid stimulus.

CD36, ADIPOQ

GO:0070544

BP

histone H3-K36 demethylation

The modification of histone H3 by the removal of a methyl group from lysine at position 36 of the histone.

KDM7A, KDM2A

GO:0070555

BP

response to interleukin-1

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-1 stimulus.

IRAK2, RIPK2, ANXA1, IL1R1, ETS1, SELE, PRKCA, CHI3L1, SNCA, PRKCI, MTHFR, GCLC, HNMT, IRAK1, HDAC4, IGBP1, RELA, AES, SLC30A8, CITED1, YTHDC2, IRAK3, TNFRSF11A

GO:0070561

BP

vitamin D receptor signaling pathway

The series of molecular signals generated as a consequence of a vitamin D receptor binding to one of its physiological ligands.

VDR

GO:0070563

BP

negative regulation of vitamin D receptor signaling pathway

Any process that stops, prevents, or reduces the frequency, rate or extent of the vitamin D receptor signaling pathway activity.

SNAI2, KANK2

GO:0070564

BP

positive regulation of vitamin D receptor signaling pathway

Any process that activates or increases the frequency, rate or extent of vitamin D receptor signaling pathway activity.

CYP27B1

GO:0070572

BP

positive regulation of neuron projection regeneration

Any process that activates or increases the frequency, rate or extent of neuron projection regeneration, the regrowth of neuronal processes such as axons or dendrites following their loss or damage.

HGF

GO:0070574

BP

cadmium ion transmembrane transport

A process in which a cadmium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.

SLC11A1, SLC11A2, SLC39A8, SLC30A1

GO:0070584

BP

mitochondrion morphogenesis

The process in which the anatomical structures of a mitochondrion are generated and organized.

NDUFS6, SSBP1, BAX, MTM1, PID1, SUPV3L1, NUBPL, PNPT1, PANK2, SLIRP, MFF, POLDIP2

GO:0070585

BP

protein localization to mitochondrion

A process in which a protein is transported to, or maintained in, a location within the mitochondrion.

PARK2, DNAJA1

GO:0070588

BP

calcium ion transmembrane transport

A process in which a calcium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.

CACNA1G, ITGAV, ATP2A2, ATP2B1, ZP3, ATP2B4, TRPC1, PSEN1, NCS1, PKD1, ATP2C1, GRIN2A, TRPC3, PKD2, CACNA1C, GAS6, RYR3, CACNA1E, ANO6, DENND5A, DENND5B, TRPV1, TRPM4, TMEM37, CACNG8, CUL5, TRPM7, PANX1, ORAI2, ORAI3, TRPM6, CACNG6, TRPV6, TRPV4, SLC24A3, STIM2, TMCO1, TRPC6, TRPV2

GO:0070602

BP

regulation of centromeric sister chromatid cohesion

Any process that modulates the frequency, rate or extent of sister chromatid cohesion in the centromeric region of a chromosome.

CTNNB1

GO:0070613

BP

regulation of protein processing

Any process that modulates the frequency, rate or extent of protein processing, any protein maturation process achieved by the cleavage of a peptide bond or bonds within a protein.

PRKACA, RPS6KA2

GO:0070625

BP

zymogen granule exocytosis

The release of intracellular molecules contained within the zymogen granule by fusion of the granule with the plasma membrane of the oocyte, requiring calcium ions.

SDF4

GO:0070627

BP

ferrous iron import

The directed movement of ferrous iron (Fe(II) or Fe2+) ions across a membrane into a cell or organelle.

SLC11A2

GO:0070633

BP

transepithelial transport

The directed movement of a substance from one side of an epithelium to the other.

CXADR, GPLD1

GO:0070634

BP

transepithelial ammonium transport

The directed movement of ammonium ions from one side of an epithelium to the other.

SLC12A2, RHBG

GO:0070640

BP

vitamin D3 metabolic process

The chemical reactions and pathways involving vitamin D3, (3S,5Z,7E)-9,10-secocholesta-5,7,10(19)-trien-3-ol.

FGFR1

GO:0070646

BP

protein modification by small protein removal

A protein modification process in which one or more covalently attached groups of a small protein, such as ubiquitin or a ubiquitin-like protein, are removed from a target protein.

SENP6

GO:0070649

BP

formin-nucleated actin cable assembly

The aggregation, arrangement and bonding together of a set of components to form a formin-nucleated actin cable. A formin-nucleated actin cable is an actin filament bundle that consists of short filaments organized into bundles of uniform polarity, and is nucleated by formins.

FMN2

GO:0070661

BP

leukocyte proliferation

The expansion of a leukocyte population by cell division.

F2RL1

GO:0070662

BP

mast cell proliferation

The expansion of a mast cell population by cell division.

KIT

GO:0070664

BP

negative regulation of leukocyte proliferation

Any process that stops, prevents, or reduces the frequency, rate or extent of leukocyte proliferation.

GSTP1, CCL8

GO:0070667

BP

negative regulation of mast cell proliferation

Any process that stops, prevents or reduces the rate or extent of mast cell proliferation.

LYN

GO:0070668

BP

positive regulation of mast cell proliferation

Any process that activates or increases the rate or extent of mast cell proliferation.

LYN, KITLG

GO:0070669

BP

response to interleukin-2

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-2 stimulus.

STAT5B, JAK3, CITED1

GO:0070670

BP

response to interleukin-4

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-4 stimulus.

STAT5B, JAK3, CITED1

GO:0070671

BP

response to interleukin-12

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-12 stimulus.

RIPK2, JAK2

GO:0070672

BP

response to interleukin-15

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-15 stimulus.

ACSL4, STAT5B, JAK3

GO:0070673

BP

response to interleukin-18

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-18 stimulus.

RIPK2

GO:0070676

BP

intralumenal vesicle formation

The invagination of the endosome membrane and resulting formation of a vesicle within the lumen of the endosome.

SNX3

GO:0070681

BP

glutaminyl-tRNAGln biosynthesis via transamidation

A tRNA aminoacylation process in which glutaminyl-tRNAGln is formed by a tRNA-dependent two-step pathway. In the first step a non-discriminating glutamyl-tRNAGlx synthetase generates the misacylated L-glutamyl-tRNAGln species, and in the second step it is amidated to the correctly charged L-glutaminyl-tRNAGln by a glutamyl-tRNAGln amidotransferase.

GATC, GATB, QRSL1

GO:0070682

BP

proteasome regulatory particle assembly

The aggregation, arrangement and bonding together of a mature, active proteasome regulatory particle complex.

PSMD10

GO:0070715

BP

sodium-dependent organic cation transport

The directed, sodium-dependent, movement of organic cations into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

SLC22A5

GO:0070723

BP

response to cholesterol

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cholesterol stimulus.

TGFB1, CCL3, TGFBR1, TGFBR2, SMAD2

GO:0070734

BP

histone H3-K27 methylation

The modification of histone H3 by addition of one or more methyl groups to lysine at position 27 of the histone.

EZH2, EZH1, EHMT2

GO:0070741

BP

response to interleukin-6

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-6 stimulus.

PCK1, CHI3L1, CITED1

GO:0070779

BP

D-aspartate import

The directed movement of D-aspartate, the L-enantiomer of the anion of 2-aminopentanedioic acid, into a cell or organelle.

SLC1A3, SLC1A2

GO:0070813

BP

hydrogen sulfide metabolic process

The chemical reactions and pathways involving hydrogen sulfide, H2S.

ETHE1

GO:0070814

BP

hydrogen sulfide biosynthetic process

The chemical reactions and pathways resulting in the formation of hydrogen sulfide, H2S.

MPST, CTH, CBS

GO:0070816

BP

phosphorylation of RNA polymerase II C-terminal domain

The process of introducing a phosphate group on to an amino acid residue in the C-terminal domain of RNA polymerase II. Typically, this occurs during the transcription cycle and results in production of an RNA polymerase II enzyme where the carboxy-terminal domain (CTD) of the largest subunit is extensively phosphorylated, often referred to as hyperphosphorylated or the II(0) form. Specific types of phosphorylation within the CTD are usually associated with specific regions of genes, though there are exceptions. The phosphorylation state regulates the association of specific complexes such as the capping enzyme or 3'-RNA processing machinery to the elongating RNA polymerase complex.

GTF2H1, CDK13, GTF2H4, CDK12

GO:0070827

BP

chromatin maintenance

The chromatin organization process that preserves chromatin in a stable functional or structural state.

SUPV3L1

GO:0070828

BP

heterochromatin organization

Any process that results in the specification, formation or maintenance of the physical structure of eukaryotic heterochromatin, a compact and highly condensed form of chromatin.

SETD7

GO:0070829

BP

heterochromatin maintenance

The chromatin organization process that preserves heterochromatin in a stable functional or structural state.

MTHFR

GO:0070830

BP

bicellular tight junction assembly

The aggregation, arrangement and bonding together of a set of components to form a tight junction, an occluding cell-cell junction that is composed of a branching network of sealing strands that completely encircles the apical end of each cell in an epithelial sheet.

CLDN3, ACTN4, CLDN1, APC, PRKCI, DLG1, OCLN, MTDH, MPP5, INADL, PARD3, MARVELD3, TBCD, PARD6B, ECT2, PARD6A, F11R

GO:0070836

BP

caveola assembly

The aggregation, arrangement and bonding together of a set of components to form a caveola. A caveola is a plasma membrane raft that forms a small pit, depression, or invagination that communicates with the outside of a cell and extends inward, indenting the cytoplasm and the cell membrane.

CAV2, CAV1

GO:0070837

BP

dehydroascorbic acid transport

The directed movement of dehydroascorbate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Dehydroascorbate, 5-(1,2-dihydroxyethyl)furan-2,3,4(5H)-trione, is an oxidized form of vitamin C.

SLC2A1, SLC2A3

GO:0070838

BP

divalent metal ion transport

The directed movement of divalent metal cations, any metal ion with a +2 electric charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

SLC41A2

GO:0070839

BP

divalent metal ion export

The directed movement of divalent metal cations, any metal ion with a +2 electric charge, out of a cell or organelle.

SLC11A1

GO:0070842

BP

aggresome assembly

The aggregation, arrangement and bonding together of a set of components to form an aggresome; requires the microtubule cytoskeleton and dynein.

UBD, PARK2, TRIM37, VCP, HDAC6

GO:0070845

BP

polyubiquitinated misfolded protein transport

The directed movement of misfolded polyubiquitinated proteins in a cell, including the movement of proteins between specific compartments or structures within a cell.

HDAC6

GO:0070846

BP

Hsp90 deacetylation

The modification of an Hsp90 protein by removal of acetyl groups.

HDAC6

GO:0070848

BP

response to growth factor

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth factor stimulus.

MYC, ANXA3, CDC34, LUM, DUSP6, GATA6, HDAC6

GO:0070849

BP

response to epidermal growth factor

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an epidermal growth factor stimulus.

TPR, MAPK3, MAPK1, ASCL1

GO:0070857

BP

regulation of bile acid biosynthetic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of bile acids.

NR1H4

GO:0070858

BP

negative regulation of bile acid biosynthetic process

Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of bile acids.

FGF19, PROX1, NR1H4

GO:0070859

BP

positive regulation of bile acid biosynthetic process

Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of bile acids.

NR1D1, STAR, STARD4

GO:0070863

BP

positive regulation of protein exit from endoplasmic reticulum

Any process that activates or increases the frequency, rate or extent of directed movement of proteins from the endoplasmic reticulum.

SORL1, SEC16B, TMEM30A

GO:0070873

BP

regulation of glycogen metabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving glycogen.

POMC, PHLDA2

GO:0070884

BP

regulation of calcineurin-NFAT signaling cascade

Any process that modulates the frequency, rate or extent of the calcineurin-NFAT signaling cascade.

NFAT5, RCAN1

GO:0070885

BP

negative regulation of calcineurin-NFAT signaling cascade

Any process that stops, prevents, or reduces the frequency, rate or extent of the calcineurin-NFAT signaling cascade.

PRNP, ATP2B4, CHP1

GO:0070886

BP

positive regulation of calcineurin-NFAT signaling cascade

Any process that activates or increases the frequency, rate or extent of signaling via the calcineurin-NFAT signaling cascade.

IGF1, ERBB3, NRG1, AKAP6, SPPL3, CIB1, LMCD1

GO:0070895

BP

negative regulation of transposon integration

Any process that stops, prevents, or reduces the frequency, rate or extent of transposon integration, a process in which a transposable element is incorporated into another DNA molecule.

ZNF93, ZNF91

GO:0070901

BP

mitochondrial tRNA methylation

The posttranscriptional addition of methyl groups to specific residues in a mitochondrial tRNA molecule.

TRMT5, HSD17B10

GO:0070903

BP

mitochondrial tRNA thio-modification

The addition a sulfur atom to a nucleotide in a mitochondrial tRNA molecule.

TRMU

GO:0070904

BP

transepithelial L-ascorbic acid transport

The directed movement of L-ascorbic acid from one side of an epithelium to the other.

SLC23A2

GO:0070911

BP

global genome nucleotide-excision repair

The nucleotide-excision repair process in which DNA lesions are removed from nontranscribed strands and from transcriptionally silent regions over the entire genome.

ERCC1, PARP1, UBC, ERCC2, XPA, GTF2H1, RAD23B, SUMO3, SUMO2, RBX1, RPS27A, UBA52, UBE2I, XPC, CUL4A, CUL4B, GTF2H2, UBE2V2, RNF111, USP45, CHD1L, GTF2H4, ERCC4

GO:0070914

BP

UV-damage excision repair

A DNA repair process that is initiated by an endonuclease that introduces a single-strand incision immediately 5' of a UV-induced damage site. UV-damage excision repair acts on both cyclobutane pyrimidine dimers (CPDs) and pyrimidine-pyrimidone 6-4 photoproducts (6-4PPs).

ERCC1, XPA, XPC, CUL4B, HIST3H2A

GO:0070925

BP

organelle assembly

The aggregation, arrangement and bonding together of a set of components to form an organelle. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.

STX7

GO:0070926

BP

regulation of ATP:ADP antiporter activity

Any process that modulates the activity of an ATP:ADP antiporter.

RIPK1

GO:0070932

BP

histone H3 deacetylation

The modification of histone H3 by the removal of one or more acetyl groups.

HDAC3, PER1, SFPQ, HDAC4, HDAC1, SIRT2, HDAC7, HDAC2, HDAC8, SMARCAD1, HDAC6, HDAC9, HDAC5

GO:0070933

BP

histone H4 deacetylation

The modification of histone H4 by the removal of one or more acetyl groups.

HDAC4, HDAC1, SIRT2, HDAC2, SMARCAD1, HDAC9

GO:0070934

BP

CRD-mediated mRNA stabilization

An mRNA stabilization process in which one or more RNA-binding proteins associate with a sequence in the open reading frame called the coding region instability determinant (CRD).

SYNCRIP, YBX1, HNRNPU

GO:0070935

BP

3'-UTR-mediated mRNA stabilization

An mRNA stabilization process in which one or more RNA-binding proteins associate with the 3'-untranslated region (UTR) of an mRNA.

HNRNPC, ZFP36, MAPKAPK2, TIRAP, TARDBP, ELAVL1, MAPK14

GO:0070936

BP

protein K48-linked ubiquitination

A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 48 of the ubiquitin monomers, is added to a protein. K48-linked ubiquitination targets the substrate protein for degradation.

TRIM38, UBE2C, PARK2, RNF8, TNFAIP3, CDC34, UBE2A, UBE2E1, TTC3, UBE2D3, UBE2H, UBE2B, SYVN1, HACE1, RNF152, RFFL, UBE2E3, PELI1, ITCH, UBE2E2, NEDD4L, RNF126, UBE2T, RNF146, RNF216, KLHL3, AMFR, RNF6, UBE2D4

GO:0070940

BP

dephosphorylation of RNA polymerase II C-terminal domain

The process of removing a phosphate group from an amino acid residue in the C-terminal domain of RNA polymerase II. Some dephosphorylation occurs during transcription while some may occur after the enzyme is released from the template in order to prepare it for the beginning of the transcription cycle again. RNA polymerase II with little or no phosphorylation is referred to as the hypophosphorylated or II(A) form.

RPRD1A, SSU72

GO:0070945

BP

neutrophil mediated killing of gram-negative bacterium

The directed killing of a gram-negative bacterium by a neutrophil.

TUSC2, TREM1

GO:0070963

BP

positive regulation of neutrophil mediated killing of gram-negative bacterium

Any process that increases the frequency, rate or extent of the directed killing of a gram-negative bacterium by a neutrophil.

F2RL1

GO:0070966

BP

nuclear-transcribed mRNA catabolic process, no-go decay

The chemical reactions and pathways resulting in the breakdown of the transcript body of a nuclear-transcribed mRNA with stalls in translation elongation.

PELO, CNOT6

GO:0070970

BP

interleukin-2 secretion

The regulated release of interleukin-2 from a cell.

PNP, GPAM

GO:0070972

BP

protein localization to endoplasmic reticulum

A process in which a protein is transported to, or maintained in, a location within the endoplasmic reticulum.

PPP1R15A, ANK2, SEC16B, VAPA

GO:0070973

BP

protein localization to endoplasmic reticulum exit site

A process in which a protein is transported to, or maintained in, a location at an endoplasmic reticulum exit site.

BCAP31, GBF1

GO:0070977

BP

bone maturation

A developmental process, independent of morphogenetic (shape) change, that is required for bone to attain its fully functional state.

GH1

GO:0070979

BP

protein K11-linked ubiquitination

A protein ubiquitination process in which ubiquitin monomers are attached to a protein, and then ubiquitin polymers are formed by linkages between lysine residues at position 11 of the ubiquitin monomers. K11-linked polyubiquitination targets the substrate protein for degradation. The anaphase-promoting complex promotes the degradation of mitotic regulators by assembling K11-linked polyubiquitin chains.

UBE2C, PARK2, CDC27, UBE2A, UBE2D3, UBE2H, UBE2B, UBE2S, UBE2E3, UBE2W, UBE2E2, ANAPC1, UBE2T, CDC23, ANAPC5, ANAPC4, FZR1, ANAPC10, UBE2D4

GO:0070981

BP

L-asparagine biosynthetic process

The chemical reactions and pathways resulting in the formation of asparagine, (2S)-2-amino-3-carbamoylpropanoic acid.

ASNS