GO ID |
Ontology |
GO Term |
Term Definition |
Proteins |
GO:0070495
|
BP
|
negative regulation of thrombin receptor signaling pathway
|
Any process that stops, prevents, or reduces the frequency, rate or extent of thrombin receptor protein signaling pathway activity. A thrombin receptor signaling pathway is the series of molecular signals generated as a consequence of a thrombin receptor binding to one of its physiological ligands.
|
SNCA
|
GO:0070498
|
BP
|
interleukin-1-mediated signaling pathway
|
A series of molecular signals initiated by the binding of interleukin-1 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
|
IRAK2,
RPS6KA5,
IL1A,
IL1R1,
EGR1,
MAPK3,
IRAK1,
PLCB1,
IRAK3
|
GO:0070507
|
BP
|
regulation of microtubule cytoskeleton organization
|
Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins.
|
EPHA3,
EFNA5,
DIXDC1,
PHLDB2,
PHLDB1,
KIF18A,
CYLD,
RASSF1,
CAMSAP3
|
GO:0070508
|
BP
|
cholesterol import
|
The directed movement of cholesterol into a cell or organelle.
|
LDLR,
APOA1,
CD36,
SCARB1,
STARD4
|
GO:0070509
|
BP
|
calcium ion import
|
The directed movement of calcium ions into a cell or organelle.
|
CASK,
CACNA1G,
CDK5,
MCUR1,
TRPV4,
SLC30A1
|
GO:0070512
|
BP
|
positive regulation of histone H4-K20 methylation
|
Any process that activates or increases the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 20 of histone H4.
|
BRCA1
|
GO:0070525
|
BP
|
tRNA threonylcarbamoyladenosine metabolic process
|
The chemical reactions and pathways involving tRNA threonylcarbamoyladenosine, a modified nucleoside found in some tRNA molecules.
|
TP53RK
|
GO:0070527
|
BP
|
platelet aggregation
|
The adhesion of one platelet to one or more other platelets via adhesion molecules.
|
CLIC1,
FGA,
FGB,
FGG,
HSPB1,
ITGB3,
PDGFRA,
MYL12A,
CSRP1,
FLNA,
MYL9,
MYH9,
PIK3CB,
PIK3CG,
ACTB,
RAP2B,
STXBP1,
ACTG1,
HBB,
GNAS,
TYRO3,
ILK,
GAS6,
GNAS,
SLC7A11,
TLN1
|
GO:0070528
|
BP
|
protein kinase C signaling
|
A series of reactions, mediated by the intracellular serine/threonine kinase protein kinase C, which occurs as a result of a single trigger reaction or compound.
|
FLOT1,
PDGFB,
ZP3,
HTR2B,
ADGRG1
|
GO:0070534
|
BP
|
protein K63-linked ubiquitination
|
A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 63 of the ubiquitin monomers, is added to a protein. K63-linked ubiquitination does not target the substrate protein for degradation, but is involved in several pathways, notably as a signal to promote error-free DNA postreplication repair.
|
WWP2,
PARK2,
RNF8,
UBE2B,
UBE2V1,
UBE2V2,
UBE2S,
RNF152,
UBE2E3,
ITCH,
ZFP91,
UBE2E2,
RNF126,
UBE2T,
PRPF19,
STUB1,
UBE2D4
|
GO:0070535
|
BP
|
histone H2A K63-linked ubiquitination
|
A histone ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 63 of the ubiquitin monomers, is added to a lysine residue in histone H2A or the variant H2AX.
|
RNF8
|
GO:0070536
|
BP
|
protein K63-linked deubiquitination
|
A protein deubiquitination process in which a K63-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 63 of the ubiquitin monomers, is removed from a protein.
|
USP27X,
TNFAIP3,
BRCC3,
ATXN3,
FAM175B,
OTUD1,
OTUD7B,
USP13,
OTUB2,
CYLD,
ZRANB1,
USP25,
USP20
|
GO:0070537
|
BP
|
histone H2A K63-linked deubiquitination
|
A protein deubiquitination process in which a K63-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 63 of the ubiquitin monomers, is removed from a lysine residue in histone H2A or the variant H2AX.
|
BRCC3
|
GO:0070541
|
BP
|
response to platinum ion
|
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a platinum stimulus.
|
ALAD
|
GO:0070542
|
BP
|
response to fatty acid
|
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fatty acid stimulus.
|
GNPAT,
TLR2,
ASS1,
FABP3,
ALAD,
CD36,
PON1,
CTGF,
PTGS2,
HMGCL,
UCP2
|
GO:0070543
|
BP
|
response to linoleic acid
|
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a linoleic acid stimulus.
|
CD36,
ADIPOQ
|
GO:0070544
|
BP
|
histone H3-K36 demethylation
|
The modification of histone H3 by the removal of a methyl group from lysine at position 36 of the histone.
|
KDM7A,
KDM2A
|
GO:0070555
|
BP
|
response to interleukin-1
|
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-1 stimulus.
|
IRAK2,
RIPK2,
ANXA1,
IL1R1,
ETS1,
SELE,
PRKCA,
CHI3L1,
SNCA,
PRKCI,
MTHFR,
GCLC,
HNMT,
IRAK1,
HDAC4,
IGBP1,
RELA,
AES,
SLC30A8,
CITED1,
YTHDC2,
IRAK3,
TNFRSF11A
|
GO:0070561
|
BP
|
vitamin D receptor signaling pathway
|
The series of molecular signals generated as a consequence of a vitamin D receptor binding to one of its physiological ligands.
|
VDR
|
GO:0070563
|
BP
|
negative regulation of vitamin D receptor signaling pathway
|
Any process that stops, prevents, or reduces the frequency, rate or extent of the vitamin D receptor signaling pathway activity.
|
SNAI2,
KANK2
|
GO:0070564
|
BP
|
positive regulation of vitamin D receptor signaling pathway
|
Any process that activates or increases the frequency, rate or extent of vitamin D receptor signaling pathway activity.
|
CYP27B1
|
GO:0070572
|
BP
|
positive regulation of neuron projection regeneration
|
Any process that activates or increases the frequency, rate or extent of neuron projection regeneration, the regrowth of neuronal processes such as axons or dendrites following their loss or damage.
|
HGF
|
GO:0070574
|
BP
|
cadmium ion transmembrane transport
|
A process in which a cadmium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
|
SLC11A1,
SLC11A2,
SLC39A8,
SLC30A1
|
GO:0070584
|
BP
|
mitochondrion morphogenesis
|
The process in which the anatomical structures of a mitochondrion are generated and organized.
|
NDUFS6,
SSBP1,
BAX,
MTM1,
PID1,
SUPV3L1,
NUBPL,
PNPT1,
PANK2,
SLIRP,
MFF,
POLDIP2
|
GO:0070585
|
BP
|
protein localization to mitochondrion
|
A process in which a protein is transported to, or maintained in, a location within the mitochondrion.
|
PARK2,
DNAJA1
|
GO:0070588
|
BP
|
calcium ion transmembrane transport
|
A process in which a calcium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
|
CACNA1G,
ITGAV,
ATP2A2,
ATP2B1,
ZP3,
ATP2B4,
TRPC1,
PSEN1,
NCS1,
PKD1,
ATP2C1,
GRIN2A,
TRPC3,
PKD2,
CACNA1C,
GAS6,
RYR3,
CACNA1E,
ANO6,
DENND5A,
DENND5B,
TRPV1,
TRPM4,
TMEM37,
CACNG8,
CUL5,
TRPM7,
PANX1,
ORAI2,
ORAI3,
TRPM6,
CACNG6,
TRPV6,
TRPV4,
SLC24A3,
STIM2,
TMCO1,
TRPC6,
TRPV2
|
GO:0070602
|
BP
|
regulation of centromeric sister chromatid cohesion
|
Any process that modulates the frequency, rate or extent of sister chromatid cohesion in the centromeric region of a chromosome.
|
CTNNB1
|
GO:0070613
|
BP
|
regulation of protein processing
|
Any process that modulates the frequency, rate or extent of protein processing, any protein maturation process achieved by the cleavage of a peptide bond or bonds within a protein.
|
PRKACA,
RPS6KA2
|
GO:0070625
|
BP
|
zymogen granule exocytosis
|
The release of intracellular molecules contained within the zymogen granule by fusion of the granule with the plasma membrane of the oocyte, requiring calcium ions.
|
SDF4
|
GO:0070627
|
BP
|
ferrous iron import
|
The directed movement of ferrous iron (Fe(II) or Fe2+) ions across a membrane into a cell or organelle.
|
SLC11A2
|
GO:0070633
|
BP
|
transepithelial transport
|
The directed movement of a substance from one side of an epithelium to the other.
|
CXADR,
GPLD1
|
GO:0070634
|
BP
|
transepithelial ammonium transport
|
The directed movement of ammonium ions from one side of an epithelium to the other.
|
SLC12A2,
RHBG
|
GO:0070640
|
BP
|
vitamin D3 metabolic process
|
The chemical reactions and pathways involving vitamin D3, (3S,5Z,7E)-9,10-secocholesta-5,7,10(19)-trien-3-ol.
|
FGFR1
|
GO:0070646
|
BP
|
protein modification by small protein removal
|
A protein modification process in which one or more covalently attached groups of a small protein, such as ubiquitin or a ubiquitin-like protein, are removed from a target protein.
|
SENP6
|
GO:0070649
|
BP
|
formin-nucleated actin cable assembly
|
The aggregation, arrangement and bonding together of a set of components to form a formin-nucleated actin cable. A formin-nucleated actin cable is an actin filament bundle that consists of short filaments organized into bundles of uniform polarity, and is nucleated by formins.
|
FMN2
|
GO:0070661
|
BP
|
leukocyte proliferation
|
The expansion of a leukocyte population by cell division.
|
F2RL1
|
GO:0070662
|
BP
|
mast cell proliferation
|
The expansion of a mast cell population by cell division.
|
KIT
|
GO:0070664
|
BP
|
negative regulation of leukocyte proliferation
|
Any process that stops, prevents, or reduces the frequency, rate or extent of leukocyte proliferation.
|
GSTP1,
CCL8
|
GO:0070667
|
BP
|
negative regulation of mast cell proliferation
|
Any process that stops, prevents or reduces the rate or extent of mast cell proliferation.
|
LYN
|
GO:0070668
|
BP
|
positive regulation of mast cell proliferation
|
Any process that activates or increases the rate or extent of mast cell proliferation.
|
LYN,
KITLG
|
GO:0070669
|
BP
|
response to interleukin-2
|
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-2 stimulus.
|
STAT5B,
JAK3,
CITED1
|
GO:0070670
|
BP
|
response to interleukin-4
|
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-4 stimulus.
|
STAT5B,
JAK3,
CITED1
|
GO:0070671
|
BP
|
response to interleukin-12
|
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-12 stimulus.
|
RIPK2,
JAK2
|
GO:0070672
|
BP
|
response to interleukin-15
|
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-15 stimulus.
|
ACSL4,
STAT5B,
JAK3
|
GO:0070673
|
BP
|
response to interleukin-18
|
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-18 stimulus.
|
RIPK2
|
GO:0070676
|
BP
|
intralumenal vesicle formation
|
The invagination of the endosome membrane and resulting formation of a vesicle within the lumen of the endosome.
|
SNX3
|
GO:0070681
|
BP
|
glutaminyl-tRNAGln biosynthesis via transamidation
|
A tRNA aminoacylation process in which glutaminyl-tRNAGln is formed by a tRNA-dependent two-step pathway. In the first step a non-discriminating glutamyl-tRNAGlx synthetase generates the misacylated L-glutamyl-tRNAGln species, and in the second step it is amidated to the correctly charged L-glutaminyl-tRNAGln by a glutamyl-tRNAGln amidotransferase.
|
GATC,
GATB,
QRSL1
|
GO:0070682
|
BP
|
proteasome regulatory particle assembly
|
The aggregation, arrangement and bonding together of a mature, active proteasome regulatory particle complex.
|
PSMD10
|
GO:0070715
|
BP
|
sodium-dependent organic cation transport
|
The directed, sodium-dependent, movement of organic cations into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
SLC22A5
|
GO:0070723
|
BP
|
response to cholesterol
|
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cholesterol stimulus.
|
TGFB1,
CCL3,
TGFBR1,
TGFBR2,
SMAD2
|
GO:0070734
|
BP
|
histone H3-K27 methylation
|
The modification of histone H3 by addition of one or more methyl groups to lysine at position 27 of the histone.
|
EZH2,
EZH1,
EHMT2
|
GO:0070741
|
BP
|
response to interleukin-6
|
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-6 stimulus.
|
PCK1,
CHI3L1,
CITED1
|
GO:0070779
|
BP
|
D-aspartate import
|
The directed movement of D-aspartate, the L-enantiomer of the anion of 2-aminopentanedioic acid, into a cell or organelle.
|
SLC1A3,
SLC1A2
|
GO:0070813
|
BP
|
hydrogen sulfide metabolic process
|
The chemical reactions and pathways involving hydrogen sulfide, H2S.
|
ETHE1
|
GO:0070814
|
BP
|
hydrogen sulfide biosynthetic process
|
The chemical reactions and pathways resulting in the formation of hydrogen sulfide, H2S.
|
MPST,
CTH,
CBS
|
GO:0070816
|
BP
|
phosphorylation of RNA polymerase II C-terminal domain
|
The process of introducing a phosphate group on to an amino acid residue in the C-terminal domain of RNA polymerase II. Typically, this occurs during the transcription cycle and results in production of an RNA polymerase II enzyme where the carboxy-terminal domain (CTD) of the largest subunit is extensively phosphorylated, often referred to as hyperphosphorylated or the II(0) form. Specific types of phosphorylation within the CTD are usually associated with specific regions of genes, though there are exceptions. The phosphorylation state regulates the association of specific complexes such as the capping enzyme or 3'-RNA processing machinery to the elongating RNA polymerase complex.
|
GTF2H1,
CDK13,
GTF2H4,
CDK12
|
GO:0070827
|
BP
|
chromatin maintenance
|
The chromatin organization process that preserves chromatin in a stable functional or structural state.
|
SUPV3L1
|
GO:0070828
|
BP
|
heterochromatin organization
|
Any process that results in the specification, formation or maintenance of the physical structure of eukaryotic heterochromatin, a compact and highly condensed form of chromatin.
|
SETD7
|
GO:0070829
|
BP
|
heterochromatin maintenance
|
The chromatin organization process that preserves heterochromatin in a stable functional or structural state.
|
MTHFR
|
GO:0070830
|
BP
|
bicellular tight junction assembly
|
The aggregation, arrangement and bonding together of a set of components to form a tight junction, an occluding cell-cell junction that is composed of a branching network of sealing strands that completely encircles the apical end of each cell in an epithelial sheet.
|
CLDN3,
ACTN4,
CLDN1,
APC,
PRKCI,
DLG1,
OCLN,
MTDH,
MPP5,
INADL,
PARD3,
MARVELD3,
TBCD,
PARD6B,
ECT2,
PARD6A,
F11R
|
GO:0070836
|
BP
|
caveola assembly
|
The aggregation, arrangement and bonding together of a set of components to form a caveola. A caveola is a plasma membrane raft that forms a small pit, depression, or invagination that communicates with the outside of a cell and extends inward, indenting the cytoplasm and the cell membrane.
|
CAV2,
CAV1
|
GO:0070837
|
BP
|
dehydroascorbic acid transport
|
The directed movement of dehydroascorbate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Dehydroascorbate, 5-(1,2-dihydroxyethyl)furan-2,3,4(5H)-trione, is an oxidized form of vitamin C.
|
SLC2A1,
SLC2A3
|
GO:0070838
|
BP
|
divalent metal ion transport
|
The directed movement of divalent metal cations, any metal ion with a +2 electric charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
SLC41A2
|
GO:0070839
|
BP
|
divalent metal ion export
|
The directed movement of divalent metal cations, any metal ion with a +2 electric charge, out of a cell or organelle.
|
SLC11A1
|
GO:0070842
|
BP
|
aggresome assembly
|
The aggregation, arrangement and bonding together of a set of components to form an aggresome; requires the microtubule cytoskeleton and dynein.
|
UBD,
PARK2,
TRIM37,
VCP,
HDAC6
|
GO:0070845
|
BP
|
polyubiquitinated misfolded protein transport
|
The directed movement of misfolded polyubiquitinated proteins in a cell, including the movement of proteins between specific compartments or structures within a cell.
|
HDAC6
|
GO:0070846
|
BP
|
Hsp90 deacetylation
|
The modification of an Hsp90 protein by removal of acetyl groups.
|
HDAC6
|
GO:0070848
|
BP
|
response to growth factor
|
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth factor stimulus.
|
MYC,
ANXA3,
CDC34,
LUM,
DUSP6,
GATA6,
HDAC6
|
GO:0070849
|
BP
|
response to epidermal growth factor
|
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an epidermal growth factor stimulus.
|
TPR,
MAPK3,
MAPK1,
ASCL1
|
GO:0070857
|
BP
|
regulation of bile acid biosynthetic process
|
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of bile acids.
|
NR1H4
|
GO:0070858
|
BP
|
negative regulation of bile acid biosynthetic process
|
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of bile acids.
|
FGF19,
PROX1,
NR1H4
|
GO:0070859
|
BP
|
positive regulation of bile acid biosynthetic process
|
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of bile acids.
|
NR1D1,
STAR,
STARD4
|
GO:0070863
|
BP
|
positive regulation of protein exit from endoplasmic reticulum
|
Any process that activates or increases the frequency, rate or extent of directed movement of proteins from the endoplasmic reticulum.
|
SORL1,
SEC16B,
TMEM30A
|
GO:0070873
|
BP
|
regulation of glycogen metabolic process
|
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving glycogen.
|
POMC,
PHLDA2
|
GO:0070884
|
BP
|
regulation of calcineurin-NFAT signaling cascade
|
Any process that modulates the frequency, rate or extent of the calcineurin-NFAT signaling cascade.
|
NFAT5,
RCAN1
|
GO:0070885
|
BP
|
negative regulation of calcineurin-NFAT signaling cascade
|
Any process that stops, prevents, or reduces the frequency, rate or extent of the calcineurin-NFAT signaling cascade.
|
PRNP,
ATP2B4,
CHP1
|
GO:0070886
|
BP
|
positive regulation of calcineurin-NFAT signaling cascade
|
Any process that activates or increases the frequency, rate or extent of signaling via the calcineurin-NFAT signaling cascade.
|
IGF1,
ERBB3,
NRG1,
AKAP6,
SPPL3,
CIB1,
LMCD1
|
GO:0070895
|
BP
|
negative regulation of transposon integration
|
Any process that stops, prevents, or reduces the frequency, rate or extent of transposon integration, a process in which a transposable element is incorporated into another DNA molecule.
|
ZNF93,
ZNF91
|
GO:0070901
|
BP
|
mitochondrial tRNA methylation
|
The posttranscriptional addition of methyl groups to specific residues in a mitochondrial tRNA molecule.
|
TRMT5,
HSD17B10
|
GO:0070903
|
BP
|
mitochondrial tRNA thio-modification
|
The addition a sulfur atom to a nucleotide in a mitochondrial tRNA molecule.
|
TRMU
|
GO:0070904
|
BP
|
transepithelial L-ascorbic acid transport
|
The directed movement of L-ascorbic acid from one side of an epithelium to the other.
|
SLC23A2
|
GO:0070911
|
BP
|
global genome nucleotide-excision repair
|
The nucleotide-excision repair process in which DNA lesions are removed from nontranscribed strands and from transcriptionally silent regions over the entire genome.
|
ERCC1,
PARP1,
UBC,
ERCC2,
XPA,
GTF2H1,
RAD23B,
SUMO3,
SUMO2,
RBX1,
RPS27A,
UBA52,
UBE2I,
XPC,
CUL4A,
CUL4B,
GTF2H2,
UBE2V2,
RNF111,
USP45,
CHD1L,
GTF2H4,
ERCC4
|
GO:0070914
|
BP
|
UV-damage excision repair
|
A DNA repair process that is initiated by an endonuclease that introduces a single-strand incision immediately 5' of a UV-induced damage site. UV-damage excision repair acts on both cyclobutane pyrimidine dimers (CPDs) and pyrimidine-pyrimidone 6-4 photoproducts (6-4PPs).
|
ERCC1,
XPA,
XPC,
CUL4B,
HIST3H2A
|
GO:0070925
|
BP
|
organelle assembly
|
The aggregation, arrangement and bonding together of a set of components to form an organelle. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.
|
STX7
|
GO:0070926
|
BP
|
regulation of ATP:ADP antiporter activity
|
Any process that modulates the activity of an ATP:ADP antiporter.
|
RIPK1
|
GO:0070932
|
BP
|
histone H3 deacetylation
|
The modification of histone H3 by the removal of one or more acetyl groups.
|
HDAC3,
PER1,
SFPQ,
HDAC4,
HDAC1,
SIRT2,
HDAC7,
HDAC2,
HDAC8,
SMARCAD1,
HDAC6,
HDAC9,
HDAC5
|
GO:0070933
|
BP
|
histone H4 deacetylation
|
The modification of histone H4 by the removal of one or more acetyl groups.
|
HDAC4,
HDAC1,
SIRT2,
HDAC2,
SMARCAD1,
HDAC9
|
GO:0070934
|
BP
|
CRD-mediated mRNA stabilization
|
An mRNA stabilization process in which one or more RNA-binding proteins associate with a sequence in the open reading frame called the coding region instability determinant (CRD).
|
SYNCRIP,
YBX1,
HNRNPU
|
GO:0070935
|
BP
|
3'-UTR-mediated mRNA stabilization
|
An mRNA stabilization process in which one or more RNA-binding proteins associate with the 3'-untranslated region (UTR) of an mRNA.
|
HNRNPC,
ZFP36,
MAPKAPK2,
TIRAP,
TARDBP,
ELAVL1,
MAPK14
|
GO:0070936
|
BP
|
protein K48-linked ubiquitination
|
A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 48 of the ubiquitin monomers, is added to a protein. K48-linked ubiquitination targets the substrate protein for degradation.
|
TRIM38,
UBE2C,
PARK2,
RNF8,
TNFAIP3,
CDC34,
UBE2A,
UBE2E1,
TTC3,
UBE2D3,
UBE2H,
UBE2B,
SYVN1,
HACE1,
RNF152,
RFFL,
UBE2E3,
PELI1,
ITCH,
UBE2E2,
NEDD4L,
RNF126,
UBE2T,
RNF146,
RNF216,
KLHL3,
AMFR,
RNF6,
UBE2D4
|
GO:0070940
|
BP
|
dephosphorylation of RNA polymerase II C-terminal domain
|
The process of removing a phosphate group from an amino acid residue in the C-terminal domain of RNA polymerase II. Some dephosphorylation occurs during transcription while some may occur after the enzyme is released from the template in order to prepare it for the beginning of the transcription cycle again. RNA polymerase II with little or no phosphorylation is referred to as the hypophosphorylated or II(A) form.
|
RPRD1A,
SSU72
|
GO:0070945
|
BP
|
neutrophil mediated killing of gram-negative bacterium
|
The directed killing of a gram-negative bacterium by a neutrophil.
|
TUSC2,
TREM1
|
GO:0070963
|
BP
|
positive regulation of neutrophil mediated killing of gram-negative bacterium
|
Any process that increases the frequency, rate or extent of the directed killing of a gram-negative bacterium by a neutrophil.
|
F2RL1
|
GO:0070966
|
BP
|
nuclear-transcribed mRNA catabolic process, no-go decay
|
The chemical reactions and pathways resulting in the breakdown of the transcript body of a nuclear-transcribed mRNA with stalls in translation elongation.
|
PELO,
CNOT6
|
GO:0070970
|
BP
|
interleukin-2 secretion
|
The regulated release of interleukin-2 from a cell.
|
PNP,
GPAM
|
GO:0070972
|
BP
|
protein localization to endoplasmic reticulum
|
A process in which a protein is transported to, or maintained in, a location within the endoplasmic reticulum.
|
PPP1R15A,
ANK2,
SEC16B,
VAPA
|
GO:0070973
|
BP
|
protein localization to endoplasmic reticulum exit site
|
A process in which a protein is transported to, or maintained in, a location at an endoplasmic reticulum exit site.
|
BCAP31,
GBF1
|
GO:0070977
|
BP
|
bone maturation
|
A developmental process, independent of morphogenetic (shape) change, that is required for bone to attain its fully functional state.
|
GH1
|
GO:0070979
|
BP
|
protein K11-linked ubiquitination
|
A protein ubiquitination process in which ubiquitin monomers are attached to a protein, and then ubiquitin polymers are formed by linkages between lysine residues at position 11 of the ubiquitin monomers. K11-linked polyubiquitination targets the substrate protein for degradation. The anaphase-promoting complex promotes the degradation of mitotic regulators by assembling K11-linked polyubiquitin chains.
|
UBE2C,
PARK2,
CDC27,
UBE2A,
UBE2D3,
UBE2H,
UBE2B,
UBE2S,
UBE2E3,
UBE2W,
UBE2E2,
ANAPC1,
UBE2T,
CDC23,
ANAPC5,
ANAPC4,
FZR1,
ANAPC10,
UBE2D4
|
GO:0070981
|
BP
|
L-asparagine biosynthetic process
|
The chemical reactions and pathways resulting in the formation of asparagine, (2S)-2-amino-3-carbamoylpropanoic acid.
|
ASNS
|