GO:0060676

BP

ureteric bud formation

The developmental process pertaining to the initial formation of the ureteric bud from the Wolffian duct. This process begins when the bud protrudes from the duct and ends when it is a recognizable bud.

GREM1

GO:0060683

BP

regulation of branching involved in salivary gland morphogenesis by epithelial-mesenchymal signaling

Any process that modulates the rate, frequency, or extent of salivary gland branching as a result of the transfer of information from the epithelial cells to the mesenchymal cells of the salivary gland.

PDGFA

GO:0060684

BP

epithelial-mesenchymal cell signaling

Any process that results in the transfer of information from an epithelial cell to a mesenchymal cell where it is interpreted.

BMP4, CDC42, WNT6

GO:0060686

BP

negative regulation of prostatic bud formation

Any process that decreases the rate, frequency, or extent of prostatic bud formation, the morphogenetic process in which a region of the fetal urogenital sinus epithelium is specified to become the prostate, resulting in prostate bud outgrowth.

BMP4, WNT5A, SULF1

GO:0060687

BP

regulation of branching involved in prostate gland morphogenesis

Any process that modulates the rate, frequency, or extent of prostate gland branching, the process in which the branching structure of the prostate gland is generated and organized. A branch is a division or offshoot from a main stem.

ESR1, BMP4, FGFR2, SFRP1

GO:0060688

BP

regulation of morphogenesis of a branching structure

Any process that modulates the rate, frequency, or extent of branching morphogenesis, the process in which the anatomical structures of branches are generated and organized.

FGFR2, PGF

GO:0060689

BP

cell differentiation involved in salivary gland development

The process in which a relatively unspecialized cell acquires specialized structural and/or functional features that characterize the cells of the salivary gland.

NFIB

GO:0060691

BP

epithelial cell maturation involved in salivary gland development

The developmental process, independent of morphogenetic (shape) change, that is required for an epithelial cell of the salivary gland to attain its fully functional state.

XBP1

GO:0060693

BP

regulation of branching involved in salivary gland morphogenesis

Any process that modulates the rate, frequency, or extent of branching morphogenesis in the salivary gland epithelium.

SNAI2, TNF

GO:0060694

BP

regulation of cholesterol transporter activity

Any process that modulates the rate, frequency, or extent of cholesterol transporter activity.

PPARG

GO:0060695

BP

negative regulation of cholesterol transporter activity

Any process that decreases the rate, frequency, or extent of cholesterol transporter activity.

APOA2

GO:0060696

BP

regulation of phospholipid catabolic process

Any process that modulates the rate, frequency, or extent of phospholipid catabolism, the chemical reactions and pathways resulting in the breakdown of phospholipids, any lipid containing phosphoric acid as a mono- or diester.

IDH1

GO:0060699

BP

regulation of endoribonuclease activity

Any process that modulates the rate, frequency or extent of the catalysis of the hydrolysis of ester linkages within ribonucleic acid by creating internal breaks.

NPM1

GO:0060702

BP

negative regulation of endoribonuclease activity

Any process that decreases the rate, frequency or extent of the catalysis of the hydrolysis of ester linkages within ribonucleic acid by creating internal breaks.

ABCE1

GO:0060706

BP

cell differentiation involved in embryonic placenta development

The process in which a relatively unspecialized cell acquires specialized features of the embryonic placenta.

KRT8, KRT19, STK4

GO:0060707

BP

trophoblast giant cell differentiation

The process in which a relatively unspecialized cell acquires specialized features of a trophoblast giant cell of the placenta. Trophoblast giant cells are the cell of the placenta that line the maternal decidua.

E2F8, PLK4, SOCS3, LIF, NR2F2, MDFI

GO:0060708

BP

spongiotrophoblast differentiation

The process in which a relatively unspecialized cell of the ectoplacental cone acquires specialized features of a spongiotrophoblast of the placenta. A spongiotrophoblast cell is a basophilic cell.

SOCS3, LIF

GO:0060709

BP

glycogen cell differentiation involved in embryonic placenta development

The process in which a relatively unspecialized cell acquires specialized features of a glycogen cell of the placenta. A glycogen cell is a vacuolated glycogen-rich cell that appears in compact cell islets of the spongiotrophoblast layer.

AKT1

GO:0060710

BP

chorio-allantoic fusion

The cell-cell adhesion process in which the cells of the chorion fuse to the cells of the allantois.

CYR61, DNAJB6, ZFP36L1

GO:0060711

BP

labyrinthine layer development

The process in which the labyrinthine layer of the placenta progresses, from its formation to its mature state.

MAP2K1, GAB1, CITED1

GO:0060712

BP

spongiotrophoblast layer development

The process in which the spongiotrophoblast layer of the placenta progresses from its formation to its mature state.

ADM, ZFP36L1, CITED1

GO:0060713

BP

labyrinthine layer morphogenesis

The process in which the labyrinthine layer of the placenta is generated and organized.

NCOA1

GO:0060715

BP

syncytiotrophoblast cell differentiation involved in labyrinthine layer development

The process in which a chorionic trophoblast cell acquires specialized features of a syncytiotrophoblast of the labyrinthine layer of the placenta.

DNAJB6, CASP8

GO:0060716

BP

labyrinthine layer blood vessel development

The process whose specific outcome is the progression of a blood vessel of the labyrinthine layer of the placenta over time, from its formation to the mature structure. The embryonic vessels grow through the layer to come in close contact with the maternal blood supply.

CYR61, HS6ST1, WNT2, JUNB, MAPK1, AKT1, PLCD1, HES1, TMED2, NSDHL, HEY1

GO:0060717

BP

chorion development

The biological process whose specific outcome is the progression of a chorion from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure. The chorion is an extraembryonic membrane.

DNAJB6

GO:0060718

BP

chorionic trophoblast cell differentiation

The process in which relatively unspecialized cells of the ectoplacental cone acquire specialized structural and/or functional features that characterize chorionic trophoblasts. These cells will migrate towards the spongiotrophoblast layer and give rise to syncytiotrophoblasts of the labyrinthine layer.

E2F8, HTRA1, MAP3K4

GO:0060721

BP

regulation of spongiotrophoblast cell proliferation

Any process that modulates the rate, frequency or extent of spongiotrophoblast cell proliferation.

NRK

GO:0060729

BP

intestinal epithelial structure maintenance

A tissue homeostatic process required for the maintenance of the structure of the intestinal epithelium.

TLR4, SOX9

GO:0060731

BP

positive regulation of intestinal epithelial structure maintenance

Any process the increases the rate, frequency or extent of intestinal epithelial structure maintenance, a tissue homeostatic process required for the maintenance of the structure of the intestinal epithelium.

SLC22A5

GO:0060732

BP

positive regulation of inositol phosphate biosynthetic process

Any process that increases the rate, frequency or extent of inositol phosphate biosynthesis. Inositol phosphate biosynthetic processes are the chemical reactions and pathways resulting in the formation of an inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with one or more phosphate groups attached.

PTAFR, SNCA, ADCYAP1R1, CD244

GO:0060733

BP

regulation of eIF2 alpha phosphorylation by amino acid starvation

Any process that modulates the rate, frequency, or extent of eIF2 alpha phosphorylation as a cellular response to amino acid starvation.

EIF2AK4, IMPACT

GO:0060734

BP

regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation

Any process that modulates the rate, frequency, or extent of eIF2 alpha phosphorylation as a cellular response to endoplasmic reticulum stress.

PPP1R15A

GO:0060735

BP

regulation of eIF2 alpha phosphorylation by dsRNA

Any process that modulates the rate, frequency, or extent of eIF2 alpha phosphorylation as a cellular response to double-stranded RNA.

NPM1

GO:0060736

BP

prostate gland growth

The increase in size or mass of the prostate gland where the increase in size or mass has the specific outcome of the progression of the gland, from its formation to its mature state.

PSAP, AR, CYP19A1, PRLR, PTEN, PLAG1

GO:0060739

BP

mesenchymal-epithelial cell signaling involved in prostate gland development

Any process that mediates the transfer of information from a mesenchymal cell to an epithelial cell where it is received and interpreted contributing to the progression of the prostate gland over time.

TNC

GO:0060740

BP

prostate gland epithelium morphogenesis

The process in which the anatomical structures of epithelia of the prostate gland are generated and organized. An epithelium consists of closely packed cells arranged in one or more layers, that covers the outer surfaces of the body or lines any internal cavity or tube.

AR, TNC, NOTCH1, ID4

GO:0060741

BP

prostate gland stromal morphogenesis

The process in which the prostate gland stroma is generated and organized. The prostate gland stroma is made up of the mesenchymal or fibroblast cells of the prostate gland.

ID4

GO:0060742

BP

epithelial cell differentiation involved in prostate gland development

The process in which a relatively unspecialized cell acquires specialized features of an epithelial cell of the prostate gland.

PSAP, AR, CTNNB1

GO:0060743

BP

epithelial cell maturation involved in prostate gland development

The developmental process, independent of morphogenetic (shape) change, that is required for an epithelial cell of the prostate gland to attain its fully functional state. An epithelial cell is a cell usually found in a two-dimensional sheet with a free surface.

FEM1B

GO:0060744

BP

mammary gland branching involved in thelarche

The process in which the branching structure of the mammary gland duct is generated and organized during the period of sexual maturity in mammals. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk.

TGFB1, AREG, WNT5A, PHB2

GO:0060745

BP

mammary gland branching involved in pregnancy

The process in which the branching structure of the mammary gland duct is generated and organized as a part of pregnancy.

ESR1, VDR

GO:0060748

BP

tertiary branching involved in mammary gland duct morphogenesis

The branching process in which the mammary gland ducts form tertiary branches off of the secondary branches as part of diestrus and pregnancy.

AR

GO:0060749

BP

mammary gland alveolus development

The progression of the mammary gland alveolus over time, from its formation to its mature state. The mammary gland alveolus is a sac-like structure that is found in the mature gland.

TNFSF11, ESR1, AR, AREG, VEGFA, PRLR, ID2, DDR1, ERBB4, PHB2, TNFRSF11A

GO:0060750

BP

epithelial cell proliferation involved in mammary gland duct elongation

The multiplication or reproduction of mammary gland branch epithelial cells, resulting in the elongation of the branch. The mammary gland branch differs from the bud in that it is not the initial curved portion of the outgrowth.

ESR1, AREG, WNT5A

GO:0060751

BP

branch elongation involved in mammary gland duct branching

The developmental growth process in which a branch of a mammary gland duct elongates.

TGFB1

GO:0060753

BP

regulation of mast cell chemotaxis

Any process that modulates the rate, frequency or extent of mast cell chemotaxis. Mast cell chemotaxis is the movement of a mast cell in response to an external stimulus.

RAC2

GO:0060754

BP

positive regulation of mast cell chemotaxis

Any process that increases the rate, frequency or extent of mast cell chemotaxis. Mast cell chemotaxis is the movement of a mast cell in response to an external stimulus.

PGF, VEGFC

GO:0060760

BP

positive regulation of response to cytokine stimulus

Any process that increases the rate, frequency, or extent of a response to cytokine stimulus.

WNT5A

GO:0060761

BP

negative regulation of response to cytokine stimulus

Any process that decreases the rate, frequency, or extent of a response to cytokine stimulus.

KLF4, APOA1, AES, MAP2K5, MAPK7

GO:0060762

BP

regulation of branching involved in mammary gland duct morphogenesis

Any process that modulates the rate, frequency, or extent of branching involved in mammary gland duct morphogenesis.

TGFB1, ETV5, WNT5A, PHB2

GO:0060763

BP

mammary duct terminal end bud growth

The morphogenetic growth of the large, club-shaped terminal end of a mammary gland duct during prepubertal growth and during puberty.

KDM5B

GO:0060764

BP

cell-cell signaling involved in mammary gland development

Any process that mediates the transfer of information from one cell to another and contributes to the progression of the mammary gland, from its initial state to the mature structure.

LRP5

GO:0060765

BP

regulation of androgen receptor signaling pathway

Any process that modulates the rate, frequency, or extent of the androgen receptor signaling pathway.

DDX5, EP300, HDAC6, RNF14, RNF6

GO:0060766

BP

negative regulation of androgen receptor signaling pathway

Any process that decreases the rate, frequency, or extent of the androgen receptor signaling pathway.

TCF21, PHB, SMARCA4, DAB2, HDAC1, SFRP1, FOXP1, HEYL

GO:0060768

BP

regulation of epithelial cell proliferation involved in prostate gland development

Any process that modulates the rate, frequency or extent of epithelial cell proliferation that contributes to the progression of the prostate gland over time.

NOTCH1

GO:0060769

BP

positive regulation of epithelial cell proliferation involved in prostate gland development

Any process that increases the rate, frequency or extent of epithelial cell proliferation that contributes to the progression of the prostate gland over time.

CTNNB1

GO:0060770

BP

negative regulation of epithelial cell proliferation involved in prostate gland development

Any process that decreases the rate, frequency or extent of epithelial cell proliferation that contributes to the progression of the prostate gland over time.

SERPINF1, CDKN1B, STK11

GO:0060775

BP

planar cell polarity pathway involved in gastrula mediolateral intercalation

The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) contributing to the interdigitation of cells along the mediolateral axis during gastrulation.

WNT5A

GO:0060784

BP

regulation of cell proliferation involved in tissue homeostasis

Any process that modulates the frequency, rate or extent of cell proliferation resulting in the maintenance of a steady-state number of cells within a tissue.

SOX9

GO:0060789

BP

hair follicle placode formation

The developmental process in which a hair placode forms. An hair follicle placode is a thickening of the ectoderm that will give rise to the hair follicle bud.

CTNNB1, CDC42, GNAS, HDAC1, GNAS, HDAC2

GO:0060800

BP

regulation of cell differentiation involved in embryonic placenta development

Any process that modulates the rate, frequency or extent of cell differentiation that contributes to the progression of the placenta over time, from its initial condition to its mature state.

STK4

GO:0060804

BP

positive regulation of Wnt signaling pathway by BMP signaling pathway

A series of molecular signals generated as a consequence of any member of the BMP (bone morphogenetic protein) family binding to a cell surface receptor that results in an increase in the rate, frequency or extent of a Wnt signaling pathway.

BMP2

GO:0060807

BP

regulation of transcription from RNA polymerase II promoter involved in definitive endodermal cell fate specification

Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that ultimately results in a cell being specified to adopt a definitive endodermal cell fate.

SOX17

GO:0060809

BP

mesodermal to mesenchymal transition involved in gastrulation

The epithelial to mesenchymal transition process in which a mesodermal cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell as part of the process of gastrulation.

WNT5A

GO:0060816

BP

random inactivation of X chromosome

Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global inactivation of all, or most of, the genes on either the paternal or maternal X-chromosome in the XX sex.

RLIM

GO:0060821

BP

inactivation of X chromosome by DNA methylation

Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global inactivation of all, or most of, the genes on one of the X-chromosomes in the XX sex by a mechanism of DNA methylation.

SMCHD1

GO:0060823

BP

canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation

The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that contributes to the formation of the neural plate anterior/posterior pattern.

AXIN1

GO:0060828

BP

regulation of canonical Wnt signaling pathway

Any process that modulates the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes.

PARK2, LRP5, FOLR1, EMD, PPP1CA, KREMEN1, MKS1, ANKRD10, BTRC

GO:0060830

BP

ciliary receptor clustering involved in smoothened signaling pathway

Grouping of smoothened or patched receptors in a cilium, contributing to the smoothened signaling pathway.

SSNA1, IFT122

GO:0060831

BP

smoothened signaling pathway involved in dorsal/ventral neural tube patterning

The series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened contributing to the dorsal/ventral pattern of the neural tube.

TULP3, GLI2, GLI3, PTCH1, IFT122

GO:0060836

BP

lymphatic endothelial cell differentiation

The process in which a venous blood vessel endothelial cell acquires specialized features of a lymphatic vessel endothelial cell, a thin flattened cell that lines the inside surfaces of lymph vessels.

ACVR2B, BMPR2, PROX1

GO:0060837

BP

blood vessel endothelial cell differentiation

The process in which a relatively unspecialized cell acquires specialized features of a blood vessel endothelial cell, a thin flattened cell that lines the inside surfaces of blood vessels.

CCM2

GO:0060840

BP

artery development

The progression of the artery over time, from its initial formation to the mature structure. An artery is a blood vessel that carries blood away from the heart to a capillary bed.

GLI3, HOXA1, ACVR2B, BMPR2

GO:0060841

BP

venous blood vessel development

The progression of the venous blood vessel over time from its initial formation to the mature structure. Venous blood vessels carry blood back to the heart after the capillary bed.

ACVR2B, BMPR2

GO:0060842

BP

arterial endothelial cell differentiation

The process in which a relatively unspecialized endothelial cell acquires specialized features of an arterial endothelial cell, a thin flattened cell that lines the inside surfaces of arteries.

NOTCH1, HEY1

GO:0060843

BP

venous endothelial cell differentiation

The process in which a relatively unspecialized endothelial cell acquires specialized features of a venous endothelial cell, a thin flattened cell that lines the inside surfaces of veins.

NOTCH1

GO:0060849

BP

regulation of transcription involved in lymphatic endothelial cell fate commitment

Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the commitment of a venous endothelial cell to a lymphatic endothelial cell.

NR2F2, PROX1

GO:0060850

BP

regulation of transcription involved in cell fate commitment

Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the commitment of a cell to a specific fate.

CEBPB, RORA, PPARG

GO:0060856

BP

establishment of blood-brain barrier

Establishment of the barrier between the blood and the brain. The cells in the brain are packed tightly together preventing the passage of most molecules from the blood into the brain. Only lipid soluble molecules or those that are actively transported can pass through the blood-brain barrier.

LSR, MFSD2A

GO:0060873

BP

anterior semicircular canal development

The progession of the anterior semicircular canal from its initial formation to the mature structure.

GLI3

GO:0060875

BP

lateral semicircular canal development

The progession of the lateral semicircular canal from its initial formation to the mature structure.

GLI3

GO:0060876

BP

semicircular canal formation

The developmental process pertaining to the initial formation of the semicircular canal from the otic vesicle. This process begins with the regionalization of the vesicle that specifies the area where the vesicles will form and continues through the process of fusion which forms the initial tubes.

HOXA1

GO:0060900

BP

embryonic camera-type eye formation

The developmental process pertaining to the initial formation of a camera-type eye from unspecified neurectoderm. This process begins with the differentiation of cells that form the optic field and ends when the optic cup has attained its shape.

TWIST1

GO:0060904

BP

regulation of protein folding in endoplasmic reticulum

Any process that modulates the rate, frequency or extent of the protein folding process that takes place in the endoplasmic reticulum (ER). Secreted, plasma membrane and organelle proteins are folded in the ER, assisted by chaperones and foldases (protein disulphide isomerases), and additional factors required for optimal folding (ATP, Ca2+ and an oxidizing environment to allow disulfide bond formation).

HSPA5

GO:0060907

BP

positive regulation of macrophage cytokine production

Any process that increases the rate, frequency or extent of macrophage cytokine production. Macrophage cytokine production is the appearance of a chemokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.

TLR4, SEMA7A, CD74, CD36, WNT5A, SPON2, GPRC5B

GO:0060912

BP

cardiac cell fate specification

The process involved in the specification of cardiac cell identity. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment.

TENM4

GO:0060913

BP

cardiac cell fate determination

The process involved in cardiac cell fate commitment. Once determination has taken place, a cell becomes committed to differentiate down a particular pathway regardless of its environment.

SOX17

GO:0060914

BP

heart formation

The developmental process pertaining to the initial formation of the heart from unspecified parts. This process begins with the specific processes that contribute to the appearance of the heart field and the arrival of cardiac neural crest to the heart region. The process ends when the structural rudiment is recognizable.

BMPR1A, SOX17

GO:0060915

BP

mesenchymal cell differentiation involved in lung development

The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal cell of the lung. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types.

FGFR2

GO:0060916

BP

mesenchymal cell proliferation involved in lung development

The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population that contributes to the progression of the lung over time. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets.

FGFR2, CTNNB1

GO:0060923

BP

cardiac muscle cell fate commitment

The commitment of cells to specific cardiac muscle cell fates and their capacity to differentiate into cardiac muscle cells. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction.

WT1, ACVR1

GO:0060931

BP

sinoatrial node cell development

The process whose specific outcome is the progression of a sinoatrial (SA) node cell over time, from its formation to the mature state. SA node cells are pacemaker cells that are found in the sinoatrial node.

BVES

GO:0060939

BP

epicardium-derived cardiac fibroblast cell development

The process whose specific outcome is the progression of an epicardial-derived cardiac fibroblast over time, from its formation to the mature state. A epicardial-derived cardiac fibroblast is a connective tissue cell of the heart that arises from the epicardium and secretes an extracellular matrix rich in collagen and other macromolecules.

TGFBR3

GO:0060947

BP

cardiac vascular smooth muscle cell differentiation

The process in which a relatively unspecialized cell acquires specialized features of a cardiac vascular smooth muscle cell. A cardiac vascular smooth muscle cell covers the heart vasculature and lacks transverse striations in its constituent fibers.

GATA6

GO:0060948

BP

cardiac vascular smooth muscle cell development

The process whose specific outcome is the progression of a cardiac vascular smooth muscle cell over time, from its formation to the mature state.

VEGFA, NOTCH1

GO:0060956

BP

endocardial cell differentiation

The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of an endocardial cell. An endocardial cell is a specialized endothelial cell that makes up the endocardium portion of the heart. The endocardium is the innermost layer of tissue of the heart, and lines the heart chambers.

NOTCH1, NRG1, SMAD4, SOX17

GO:0060964

BP

regulation of gene silencing by miRNA

Any process that modulates the rate, frequency, or extent of the downregulation of gene expression through the action of microRNAs (miRNAs), endogenous 21-24 nucleotide small RNAs processed from stem-loop RNA precursors (pre-miRNAs). Once incorporated into a RNA-induced silencing complex (RISC), miRNAs can downregulate gene expression by either of two posttranscriptional mechanisms: mRNA cleavage or translational repression.

FMR1, PUM1, PUM2, LIN28A

GO:0060965

BP

negative regulation of gene silencing by miRNA

Any process that decreases the rate, frequency, or extent of the downregulation of gene expression through the action of microRNAs (miRNAs), endogenous 21-24 nucleotide small RNAs processed from stem-loop RNA precursors (pre-miRNAs). Once incorporated into a RNA-induced silencing complex (RISC), miRNAs can downregulate gene expression by either of two posttranscriptional mechanisms: mRNA cleavage or translational repression.

TGFB1, POU5F1, ELAVL1

GO:0060968

BP

regulation of gene silencing

Any process that modulates the rate, frequency, or extent of gene silencing, the transcriptional or post-transcriptional process carried out at the cellular level that results in long-term gene inactivation.

CDK2, HIST1H3D

GO:0060971

BP

embryonic heart tube left/right pattern formation

The pattern specification process that results in the subdivision of the left/right axis of the embryonic heart tube in space to define an area or volume in which specific patterns of cell differentiation will take place.

CITED2, IFT122