GO ID |
Ontology |
GO Term |
Term Definition |
Proteins |
GO:0060039
|
BP
|
pericardium development
|
The process whose specific outcome is the progression of the pericardium over time, from its formation to the mature structure. The pericardium is a double-walled sac that contains the heart and the roots of the aorta, vena cava and the pulmonary artery.
|
BMP2,
SMAD3,
SMAD2,
CCM2,
HEG1
|
GO:0060041
|
BP
|
retina development in camera-type eye
|
The process whose specific outcome is the progression of the retina over time, from its formation to the mature structure. The retina is the innermost layer or coating at the back of the eyeball, which is sensitive to light and in which the optic nerve terminates.
|
NPHP1,
GRM6,
PAX4,
SKI,
RRM1,
SERPINF1,
SOX9,
LHX2,
SOX8,
GNB1,
RPL24,
BAX,
MERTK,
NECTIN1,
NTRK2,
JMJD6,
PAPD4,
ZNF513,
MDM1,
PFDN5,
CHD7,
LAMC3
|
GO:0060042
|
BP
|
retina morphogenesis in camera-type eye
|
The process in which the anatomical structure of the retina is generated and organized.
|
LRP5,
PROX1,
NECTIN3
|
GO:0060043
|
BP
|
regulation of cardiac muscle cell proliferation
|
Any process that modulates the frequency, rate or extent of cardiac muscle cell proliferation.
|
BMPR1A,
TGFBR1
|
GO:0060044
|
BP
|
negative regulation of cardiac muscle cell proliferation
|
Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle cell proliferation.
|
RBP4,
GJA1,
TGFBR2,
PTEN
|
GO:0060045
|
BP
|
positive regulation of cardiac muscle cell proliferation
|
Any process that activates or increases the frequency, rate or extent of cardiac muscle cell proliferation.
|
BMP10,
CDK1,
FGF2,
WNT2,
FGFR1,
CCNB1,
FGFR2,
FGF9,
BMPR1A,
NOTCH1,
TGFBR3,
MEF2C,
ERBB4,
MAPK14,
ZFPM2,
GATA6
|
GO:0060046
|
BP
|
regulation of acrosome reaction
|
Any process that modulates the frequency, rate or extent of the acrosome reaction.
|
SPINK1,
B4GALT1
|
GO:0060047
|
BP
|
heart contraction
|
The multicellular organismal process in which the heart decreases in volume in a characteristic way to propel blood through the body.
|
GPX1,
ACE,
TNNI3,
CDC42,
ACTC1,
RPS6KA2,
SGCD,
SGCZ
|
GO:0060048
|
BP
|
cardiac muscle contraction
|
Muscle contraction of cardiac muscle tissue.
|
ATP1B1,
TPM1,
GAA,
DMD,
MYL4,
TNNI3,
PIK3CA,
VEGFB,
ATP1A2,
MAP2K6,
ACTC1,
SRSF1,
KCNH2,
PPP1R13L,
TTN,
RYR2,
SMAD5
|
GO:0060049
|
BP
|
regulation of protein glycosylation
|
Any process that modulates the frequency, rate or extent of protein glycosylation. Protein glycosylation is the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid, e.g. the addition of glycan chains to proteins.
|
MT3
|
GO:0060050
|
BP
|
positive regulation of protein glycosylation
|
Any process that activates or increases the frequency, rate or extent of the glycosylation of one or more amino acid residues within a protein. Protein glycosylation is the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid, e.g. the addition of glycan chains to proteins.
|
RAMP1,
GOLGA2,
CHP1
|
GO:0060052
|
BP
|
neurofilament cytoskeleton organization
|
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising neurofilaments and their associated proteins.
|
NDEL1
|
GO:0060054
|
BP
|
positive regulation of epithelial cell proliferation involved in wound healing
|
Any process that activates or increases the rate or extent of epithelial cell proliferation, contributing to the restoration of integrity to a damaged tissue following an injury.
|
FZD7,
B4GALT1
|
GO:0060055
|
BP
|
angiogenesis involved in wound healing
|
Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to a damaged tissue, following an injury.
|
ITGB3,
GPX1,
ETS1,
B4GALT1,
PIK3CB,
HPSE
|
GO:0060056
|
BP
|
mammary gland involution
|
The tissue remodeling that removes differentiated mammary epithelia during weaning.
|
IGFBP5,
ELF3,
CAV1
|
GO:0060058
|
BP
|
positive regulation of apoptotic process involved in mammary gland involution
|
Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process of mammary epithelial cells during mammary gland involution.
|
VDR,
B4GALT1,
BAX
|
GO:0060059
|
BP
|
embryonic retina morphogenesis in camera-type eye
|
The process in which the anatomical structure of the retina is generated and organized in a camera-type eye during the embryonic life stage.
|
LRP6,
RBP4,
PROX1,
HIPK2
|
GO:0060064
|
BP
|
Spemann organizer formation at the anterior end of the primitive streak
|
Formation of the specialized region at the anterior end of the primitive streak of the embryo that acts as the main signaling center establishing the body plan.
|
WNT3
|
GO:0060065
|
BP
|
uterus development
|
The reproductive developmental process whose specific outcome is the progression of the uterus over time, from its formation to the mature structure.
|
RBP4,
ESR1,
HOXA10,
WNT5A,
CDKN1C,
FOXL2,
TGFB2,
SMAD4
|
GO:0060066
|
BP
|
oviduct development
|
The reproductive developmental process whose specific outcome is the progression of an oviduct over time, from its formation to the mature structure. An oviduct is a tube through which an ova passes from the ovary to the uterus, or from the ovary to the outside of the organism.
|
CTNNB1
|
GO:0060067
|
BP
|
cervix development
|
The reproductive developmental process whose specific outcome is the progression of the cervix over time, from its formation to the mature structure.
|
WNT5A
|
GO:0060068
|
BP
|
vagina development
|
The reproductive developmental process whose specific outcome is the progression of the vagina over time, from its formation to the mature structure.
|
RBP4,
ESR1,
WNT5A,
TYRO3,
BAX,
MERTK
|
GO:0060070
|
BP
|
canonical Wnt signaling pathway
|
The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes.
|
AXIN1,
KDM6A,
KLF4,
SNAI2,
TBL1X,
FZD7,
LRP5,
LRP6,
MYC,
WNT2,
SDC1,
APC,
CTNNB1,
WNT5A,
NR4A2,
PSEN1,
GSK3B,
WNT3,
PTEN,
CDC42,
UBE2B,
SMAD3,
NDP,
SOX4,
PTK7,
DIXDC1,
STK11,
SFRP1,
RYR2,
MED12,
WNT2B,
PYGO2,
TBL1XR1,
FZD8,
SOX17,
CHD8,
TCF7L1,
TCF7L2,
FZD4
|
GO:0060071
|
BP
|
Wnt signaling pathway, planar cell polarity pathway
|
The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity.
|
PSMD11,
PSMD12,
PSMD3,
FZD6,
FZD7,
GPC4,
PSMD10,
AP2A2,
PFN1,
UBC,
PSMC3,
PSMB1,
PSMA1,
PSMA2,
PSMA3,
PSMA4,
PSMB8,
PSMB9,
PSMB4,
PSMB5,
PSMC2,
PSMB10,
WNT5A,
PSMC4,
PSMB3,
PSMD7,
AP2S1,
CDC42,
PSME3,
RHOA,
PSMC1,
PSMC6,
RPS27A,
UBA52,
RAC1,
AP2B1,
ROR1,
TIAM1,
PSMD2,
PSME4,
MED12,
CTHRC1,
AP2M1,
PRICKLE1,
SMURF2,
PARD6A,
CELSR3,
FZD4,
DAAM1,
GPC6
|
GO:0060073
|
BP
|
micturition
|
The regulation of body fluids process in which parasympathetic nerves stimulate the bladder wall muscle to contract and expel urine from the body.
|
ADRA1A,
KCNMA1
|
GO:0060074
|
BP
|
synapse maturation
|
The process that organizes a synapse so that it attains its fully functional state. Synaptic maturation plays a critical role in the establishment of effective synaptic connections in early development.
|
PTEN
|
GO:0060075
|
BP
|
regulation of resting membrane potential
|
Any process that modulates the establishment or extent of a resting potential, the electrical charge across the plasma membrane, with the interior of the cell negative with respect to the exterior. The resting potential is the membrane potential of a cell that is not stimulated to be depolarized or hyperpolarized.
|
KCNK1,
PSEN1,
KCNK6
|
GO:0060078
|
BP
|
regulation of postsynaptic membrane potential
|
Any process that modulates the potential difference across a post-synaptic membrane.
|
PKD2,
SCN9A,
FGF14
|
GO:0060079
|
BP
|
excitatory postsynaptic potential
|
A process that leads to a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential.
|
ADORA1,
SNCA,
CDK5,
MEF2C,
PPP3CA,
GRIN2A,
MAPK8IP2,
RAB3GAP1,
SLC29A1,
GHRL
|
GO:0060081
|
BP
|
membrane hyperpolarization
|
The process in which membrane potential increases with respect to its steady-state potential, usually from negative potential to a more negative potential. For example, during the repolarization phase of an action potential the membrane potential often becomes more negative or hyperpolarized before returning to the steady-state resting potential.
|
CFTR,
CASP1,
ADIPOQ
|
GO:0060083
|
BP
|
smooth muscle contraction involved in micturition
|
The process leading to shortening and/or development of tension in the urinary bladder smooth muscle tissue involved in the expulsion urine from the body.
|
KCNMA1,
TRPV1
|
GO:0060086
|
BP
|
circadian temperature homeostasis
|
Any homeostatic process in which an organism modulates its internal body temperature at different values with a regularity of approximately 24 hours.
|
NR1D1,
TNFRSF11A
|
GO:0060087
|
BP
|
relaxation of vascular smooth muscle
|
A process in which the extent of vascular smooth muscle contraction is reduced. Vascular smooth muscle relaxation is mediated via a decrease in the phosphorylation state of myosin light chain. This can be achieved by removal of calcium from the cytoplasm to the sarcoplasmic reticulum lumen through the action of Ca2+ ATPases leading to a decrease myosin light chain kinase activity, and through calcium-independent pathways leading to a increase in myosin light chain phosphatase activity.
|
ADORA2B,
ADORA1,
RGS2
|
GO:0060088
|
BP
|
auditory receptor cell stereocilium organization
|
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a stereocilium. A stereocilium is an actin-based protrusion from the apical surface of auditory hair cells.
|
CLIC5
|
GO:0060100
|
BP
|
positive regulation of phagocytosis, engulfment
|
Any process that activates or increases the frequency, rate or extent of the internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis.
|
CD36,
ITGA2,
PPARG,
F2RL1,
ANO6
|
GO:0060112
|
BP
|
generation of ovulation cycle rhythm
|
The process which controls the timing of the type of sexual cycle seen in female mammals.
|
CHRNA7,
KISS1,
NPY5R
|
GO:0060113
|
BP
|
inner ear receptor cell differentiation
|
The process in which relatively unspecialized cells, acquire specialized structural and/or functional features of inner ear receptor cells. Inner ear receptor cells are mechanorecptors found in the inner ear responsible for transducing signals involved in balance and sensory perception of sound.
|
BMP4
|
GO:0060117
|
BP
|
auditory receptor cell development
|
The process whose specific outcome is the progression of an auditory receptor cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.
|
FGFR1
|
GO:0060119
|
BP
|
inner ear receptor cell development
|
The process whose specific outcome is the progression of an inner ear receptor cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.
|
ATP8B1,
GABRA5,
NAGLU
|
GO:0060122
|
BP
|
inner ear receptor stereocilium organization
|
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a stereocilium. A stereocilium is an actin-based protrusion from the apical surface of inner ear receptor cells.
|
SDC4,
HES1,
TRIP11,
CTHRC1,
IFT27,
MKS1
|
GO:0060123
|
BP
|
regulation of growth hormone secretion
|
Any process that modulates the frequency, rate or extent of the regulated release of growth hormone from a cell.
|
CHD7
|
GO:0060124
|
BP
|
positive regulation of growth hormone secretion
|
Any process that increases the frequency, rate or extent of the regulated release of growth hormone from a cell.
|
GHRH,
DRD2,
ARHGEF7,
KISS1,
GHRL
|
GO:0060125
|
BP
|
negative regulation of growth hormone secretion
|
Any process that decreases or stops the frequency, rate or extent of the regulated release of growth hormone from a cell.
|
PTPN11
|
GO:0060126
|
BP
|
somatotropin secreting cell differentiation
|
The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a somatotropin secreting cell. A somatotropin secreting cell is an acidophilic cell of the anterior pituitary that produces growth hormone, somatotropin.
|
PITX2
|
GO:0060127
|
BP
|
prolactin secreting cell differentiation
|
The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a prolactin secreting cell. A prolactin secreting cell is an acidophilic cell of the anterior pituitary that produces prolactin.
|
PITX2
|
GO:0060128
|
BP
|
corticotropin hormone secreting cell differentiation
|
The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a corticotropic hormone secreting cell. An corticotropic hormone secreting cell is a basophil cell of the anterior pituitary that produces corticotropin.
|
BMP2
|
GO:0060129
|
BP
|
thyroid-stimulating hormone-secreting cell differentiation
|
The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a thyroid-stimulating hormone-secreting cell. A thyroid-stimulating hormone-secreting cell is a basophil cell of the anterior pituitary that produces thyroid-stimulating hormone, thyrotrophin.
|
BMP2
|
GO:0060134
|
BP
|
prepulse inhibition
|
The process in which a startle magnitude is reduced when the startling stimulus is preceded by a low-intensity prepulse.
|
DRD2,
CTNNA2,
PTEN,
NRXN1
|
GO:0060135
|
BP
|
maternal process involved in female pregnancy
|
A reproductive process occurring in the mother that allows an embryo or fetus to develop within it.
|
AGRP,
ANGPT2,
CCL2,
AKR1B1,
PAM,
CNR1,
ITGA3,
UBE2A,
ADCY7,
PPAT,
DSG2,
APOL2
|
GO:0060136
|
BP
|
embryonic process involved in female pregnancy
|
A reproductive process occurring in the embryo or fetus that allows the embryo or fetus to develop within the mother.
|
ACSL4,
JUNB,
HSF1,
SP3
|
GO:0060137
|
BP
|
maternal process involved in parturition
|
A reproductive process occurring in the mother that results in birth.
|
CYP1A1,
EDN1,
CCL2,
OXTR
|
GO:0060139
|
BP
|
positive regulation of apoptotic process by virus
|
Any viral process that activates or increases the frequency, rate or extent of cell death by apoptotic process.
|
BCL2L11,
BAD
|
GO:0060143
|
BP
|
positive regulation of syncytium formation by plasma membrane fusion
|
Any process that increases the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells.
|
CAMK1
|
GO:0060154
|
BP
|
cellular process regulating host cell cycle in response to virus
|
Any cellular process that modulates the rate or extent of progression through the cell cycle in response to a virus.
|
BCL2L11,
BAD
|
GO:0060155
|
BP
|
platelet dense granule organization
|
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a platelet dense granule. A platelet dense granule is an electron-dense granule occurring in blood platelets that stores and secretes adenosine nucleotides and serotonin. They contain a highly condensed core consisting of serotonin, histamine, calcium, magnesium, ATP, ADP, pyrophosphate and membrane lysosomal proteins.
|
ABCA1,
F2R,
BLOC1S1,
BLOC1S3
|
GO:0060156
|
BP
|
milk ejection
|
An automatic response to suckling, beginning with a nerve impulse from a receptor in the mammary gland and ending with the ejection of milk from the gland. Signaling never reaches a level of consciousness.
|
GJA1
|
GO:0060157
|
BP
|
urinary bladder development
|
The process whose specific outcome is the progression of the urinary bladder over time, from its formation to the mature structure. The urinary bladder is an elastic, muscular sac situated in the anterior part of the pelvic cavity in which urine collects before excretion.
|
RBP4,
WNT5A
|
GO:0060158
|
BP
|
phospholipase C-activating dopamine receptor signaling pathway
|
The series of molecular signals generated as a consequence of a dopamine receptor binding to its physiological ligand, where the pathway proceeds with activation of phospholipase C (PLC) and a subsequent release of inositol trisphosphate (IP3) and diacylglycerol (DAG).
|
DRD2,
GNA11,
GNAQ
|
GO:0060160
|
BP
|
negative regulation of dopamine receptor signaling pathway
|
Any process that stops, prevents, or reduces the frequency, rate or extent of dopamine receptor protein signaling pathway activity. A dopamine receptor signaling pathway is the series of molecular signals generated as a consequence of a dopamine receptor binding to one of its physiological ligands.
|
DRD2
|
GO:0060161
|
BP
|
positive regulation of dopamine receptor signaling pathway
|
Any process that activates or increases the frequency, rate or extent of the dopamine receptor protein signaling pathway. A dopamine receptor signaling pathway is the series of molecular signals generated as a consequence of a dopamine receptor binding to one of its physiological ligands.
|
CAV2,
VPS35
|
GO:0060163
|
BP
|
subpallium neuron fate commitment
|
The process in which in the subpallium, the developmental fate of a cell becomes restricted such that it will develop into a neuron. The subpallium is the base region of the telencephalon.
|
ASCL1
|
GO:0060164
|
BP
|
regulation of timing of neuron differentiation
|
The process controlling the activation and/or rate at which a relatively unspecialized cell acquires features of a neuron.
|
HES1
|
GO:0060165
|
BP
|
regulation of timing of subpallium neuron differentiation
|
The process controlling the timing and/or rate at which a relatively unspecialized cell in the subpallium acquires features of a neuron. The subpallium is the base region of the telencephalon.
|
ASCL1
|
GO:0060166
|
BP
|
olfactory pit development
|
The biological process whose specific outcome is the progression of the olfactory pit from an initial condition to its mature state. This process begins with the formation of the olfactory pit, which is an indentation of the olfactory placode, and ends when the pits hollows out to form the nasopharynx.
|
ALDH1A3,
ASCL1,
DLX5
|
GO:0060168
|
BP
|
positive regulation of adenosine receptor signaling pathway
|
Any process that activates or increases the frequency, rate or extent of the adenosine receptor signaling pathway. The adenosine receptor pathway is the series of molecular signals generated as a consequence of an adenosine receptor binding to one of its physiological ligands.
|
ACPP
|
GO:0060169
|
BP
|
negative regulation of adenosine receptor signaling pathway
|
Any process that stops, prevents, or reduces the frequency, rate or extent of the adenosine receptor signaling pathway. The adenosine receptor pathway is the series of molecular signals generated as a consequence of an adenosine receptor binding to one of its physiological ligands.
|
ADA
|
GO:0060173
|
BP
|
limb development
|
The process whose specific outcome is the progression of a limb over time, from its formation to the mature structure. A limb is an appendage of an animal used for locomotion or grasping. Examples include legs, arms or some types of fin.
|
GREM1,
PAM,
NR2F2,
COMP,
BMPR2,
BBS7,
LNP,
RC3H2,
IFT122,
ZAK,
CHD7,
INTU
|
GO:0060174
|
BP
|
limb bud formation
|
The process pertaining to the initial formation of a limb bud from unspecified parts. This process begins with the formation of a local condensation of mesenchyme cells within the prospective limb field, and ends when a limb bud is recognizable.
|
PLXNA2,
FGFR2,
SOX9,
WNT3,
SOX4,
SEMA3C
|
GO:0060177
|
BP
|
regulation of angiotensin metabolic process
|
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving angiotensin.
|
ACE
|
GO:0060178
|
BP
|
regulation of exocyst localization
|
Any process that modulates the localization of exocysts. An exocyst is a protein complex peripherally associated with the plasma membrane that determines where vesicles dock and fuse.
|
RALB
|
GO:0060179
|
BP
|
male mating behavior
|
The specific behavior of a male organism that is associated with reproduction.
|
PTEN,
NCOA1
|
GO:0060192
|
BP
|
negative regulation of lipase activity
|
Any process that decreases the frequency, rate or extent of lipase activity, the hydrolysis of a lipid or phospholipid.
|
APOA1,
APOA2,
PLIN5
|
GO:0060193
|
BP
|
positive regulation of lipase activity
|
Any process that increases the frequency, rate or extent of lipase activity, the hydrolysis of a lipid or phospholipid.
|
RHOA,
PLIN5
|
GO:0060197
|
BP
|
cloacal septation
|
The separation of the single opening of the digestive, urinary, and reproductive tracts, the cloaca, into multiple isolated openings during development.
|
BMP4
|
GO:0060213
|
BP
|
positive regulation of nuclear-transcribed mRNA poly(A) tail shortening
|
Any process that increases the frequency, rate or extent of poly(A) tail shortening of a nuclear-transcribed mRNA. Poly(A) tail shortening is the decrease in length of the poly(A) tail of an mRNA from full length to an oligo(A) length.
|
CNOT1,
ZFP36,
POLR2G,
BTG2,
CPEB3,
TNRC6C,
CNOT7,
AGO2,
TNRC6B
|
GO:0060214
|
BP
|
endocardium formation
|
Formation of the endocardium of the heart. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers.
|
PROX1,
SOX17
|
GO:0060215
|
BP
|
primitive hemopoiesis
|
A first transient wave of blood cell production that, in vertebrates, gives rise to erythrocytes (red blood cells) and myeloid cells.
|
STK4
|
GO:0060216
|
BP
|
definitive hemopoiesis
|
A second wave of blood cell production that, in vertebrates, generates long-term hemopoietic stem cells that continously provide erythroid, myeloid and lymphoid lineages throughout adulthood.
|
MEIS1,
TAL1,
ZFP36L2,
SP3,
TEK,
TGFBR3,
MFAP5,
CBFB
|
GO:0060217
|
BP
|
hemangioblast cell differentiation
|
The process in which a relatively unspecialized cell acquires the characteristics of a mature hemangioblast. Hemangioblasts are the proposed common precursor of blood and endothelial lineages.
|
TAL1
|
GO:0060218
|
BP
|
hematopoietic stem cell differentiation
|
The process in which a relatively unspecialized cell acquires specialized features of a hematopoietic stem cell. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells.
|
CHD2,
ACE,
XRCC5,
TAL1,
ERCC2,
MEOX1,
CDK6,
SFRP1
|
GO:0060219
|
BP
|
camera-type eye photoreceptor cell differentiation
|
The process in which a relatively unspecialized cell acquires the specialized features of a photoreceptor cell in a camera-type eye.
|
SDK2
|
GO:0060221
|
BP
|
retinal rod cell differentiation
|
The process in which a relatively unspecialized cell acquires the specialized features of a retinal rod cell.
|
SOX9,
SOX8
|
GO:0060231
|
BP
|
mesenchymal to epithelial transition
|
A transition where a mesenchymal cell establishes apical/basolateral polarity, forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell.
|
FZD7,
WT1,
TCF15,
CITED1
|
GO:0060235
|
BP
|
lens induction in camera-type eye
|
Signaling at short range between the head ectoderm and the optic vesicle that results in the head ectoderm forming a lens.
|
BMP4,
HIPK2
|
GO:0060236
|
BP
|
regulation of mitotic spindle organization
|
Any process that modulates the rate, frequency or extent of the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle during a mitotic cell cycle.
|
PKD1,
PSRC1,
BORA,
TPX2,
TACC3
|
GO:0060242
|
BP
|
contact inhibition
|
The cellular process in which cells stop growing or dividing in response to increased cell density.
|
TSPO,
YAP1,
PTPRJ
|
GO:0060243
|
BP
|
negative regulation of cell growth involved in contact inhibition
|
The negative regulation of cell growth in response to increased cell density.
|
CDHR2
|
GO:0060244
|
BP
|
negative regulation of cell proliferation involved in contact inhibition
|
Any process that stops, prevents or reduces the rate or extent of cell proliferation in response to cell density.
|
DACH1
|
GO:0060251
|
BP
|
regulation of glial cell proliferation
|
Any process that modulates the frequency, rate or extent of glial cell proliferation.
|
CREB1
|
GO:0060252
|
BP
|
positive regulation of glial cell proliferation
|
Any process that activates or increases the rate or extent of glial cell proliferation.
|
LYN,
TSPO,
ETV5,
PRKCI,
PLAG1
|
GO:0060253
|
BP
|
negative regulation of glial cell proliferation
|
Any process that stops or decreases the rate or extent of glial cell proliferation.
|
TSPO,
NOTCH1,
HES1
|
GO:0060259
|
BP
|
regulation of feeding behavior
|
Any process that modulates the rate, frequency or extent of the behavior associated with the intake of food.
|
AGRP,
CNR1,
STAT3,
LEPR,
EIF2AK4
|
GO:0060261
|
BP
|
positive regulation of transcription initiation from RNA polymerase II promoter
|
Any process that increases the rate, frequency or extent of a process involved in starting transcription from an RNA polymerase II promoter.
|
GTF2F2,
HNF1A
|
GO:0060263
|
BP
|
regulation of respiratory burst
|
Any process that modulates the rate frequency or extent of a phase of elevated metabolic activity, during which oxygen consumption increases; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals.
|
RAC2,
RAC1,
NOXA1
|
GO:0060266
|
BP
|
negative regulation of respiratory burst involved in inflammatory response
|
Any process that decreases the rate, frequency or extent of a phase of elevated metabolic activity, during which oxygen consumption increases made as a defense response ; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals.
|
INS,
DUSP10
|
GO:0060267
|
BP
|
positive regulation of respiratory burst
|
Any process that increases the rate frequency or extent of a phase of elevated metabolic activity, during which oxygen consumption increases; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals.
|
INS,
INSR,
CAMK1D
|
GO:0060271
|
BP
|
cilium morphogenesis
|
A process that is carried out at the cellular level and in which the structure of a cilium is organized.
|
PTPDC1,
UNC119B,
C21orf2,
OFD1,
TROVE2,
NOTCH1,
ACTR3,
SEPT7,
TCTN3,
NPHP3,
BBS7,
AHI1,
IQUB,
IFT43,
C5orf30,
TCTN2,
BBS2,
IFT122,
MKKS,
PARVA,
MKS1,
CC2D2A,
ASAP1,
B9D1,
KIF3A
|
GO:0060272
|
BP
|
embryonic skeletal joint morphogenesis
|
The process in which the anatomical structures of skeletal joints are generated and organized during the embryonic phase. A skeletal joint is the connecting structure between the bones of the skeleton.
|
AXIN1,
SHOX2,
BMP4,
OSR1
|
GO:0060279
|
BP
|
positive regulation of ovulation
|
Any process that activates or increases the frequency, rate or extent of ovulation, the release of a mature ovum/oocyte from an ovary.
|
INHBA,
INHBB
|
GO:0060282
|
BP
|
positive regulation of oocyte development
|
Any process that increases the rate or extent of the process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell.
|
PDE5A,
PDE3A
|