GO ID |
Ontology |
GO Term |
Term Definition |
Proteins |
GO:0051930
|
BP
|
regulation of sensory perception of pain
|
Any process that modulates the frequency, rate or extent of the sensory perception of pain, the series of events required for an organism to receive a painful stimulus, convert it to a molecular signal, and recognize and characterize the signal.
|
EDN1,
CCK,
CCL3,
ACPP,
COMT,
F2R,
ADORA1,
NPY2R,
GRIN2A,
MGLL,
PROL1,
SPX
|
GO:0051932
|
BP
|
synaptic transmission, GABAergic
|
The process of communication from a neuron to another neuron across a synapse using the neurotransmitter gamma-aminobutyric acid (GABA).
|
RAC3,
RAC1
|
GO:0051938
|
BP
|
L-glutamate import
|
The directed movement of L-glutamate, the L-enantiomer of the anion of 2-aminopentanedioic acid, into a cell or organelle.
|
SLC1A3,
SLC1A2
|
GO:0051939
|
BP
|
gamma-aminobutyric acid import
|
The directed movement of gamma-aminobutyric acid (GABA, 4-aminobutyrate) into a cell or organelle.
|
SLC6A1
|
GO:0051946
|
BP
|
regulation of glutamate uptake involved in transmission of nerve impulse
|
Any process that modulates the frequency, rate or extent of the directed movement of L-glutamate into a neuron or glial cell.
|
ATP1A2
|
GO:0051958
|
BP
|
methotrexate transport
|
The directed movement of methotrexate, 4-amino-10-methylformic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Methotrexate is a folic acid analogue and a potent competitive inhibitor of dihydrofolate reductase.
|
SLC19A1,
SLC46A1
|
GO:0051963
|
BP
|
regulation of synapse assembly
|
Any process that modulates the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse.
|
MEF2C,
NECTIN1,
GHSR,
PDLIM5
|
GO:0051964
|
BP
|
negative regulation of synapse assembly
|
Any process that stops, prevents, or reduces the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse.
|
WNT5A,
PTK2,
ROBO2
|
GO:0051965
|
BP
|
positive regulation of synapse assembly
|
Any process that activates, maintains or increases the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse.
|
FLRT2,
SRPX2,
CLSTN1,
NTRK1,
CBLN1,
BDNF,
EPHB2,
OXTR,
EFNA5,
EPHB1,
UBE2V2,
ASIC2,
NTRK2,
LRRN1,
LINGO2,
SLITRK4,
NLGN1,
CLSTN2,
ADGRL3,
IL1RAP,
FLRT3,
FLRT1,
GHRL,
NRXN1
|
GO:0051966
|
BP
|
regulation of synaptic transmission, glutamatergic
|
Any process that modulates the frequency, rate or extent of glutamatergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glutamate.
|
GRM8,
GRM6,
DKK1,
SERPINE2,
CNR1,
SYT1,
PSEN1,
ATP1A2,
MEF2C,
MAPK8IP2,
GRM3
|
GO:0051967
|
BP
|
negative regulation of synaptic transmission, glutamatergic
|
Any process that stops, prevents, or reduces the frequency, rate or extent of glutamatergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glutamate.
|
DRD2,
ADORA1,
NPY2R,
ATAD1
|
GO:0051968
|
BP
|
positive regulation of synaptic transmission, glutamatergic
|
Any process that activates, maintains or increases the frequency, rate or extent of glutamatergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glutamate.
|
EGFR,
NTRK1,
OXTR,
PTGS2,
NLGN1,
TNR,
NRXN1
|
GO:0051969
|
BP
|
regulation of transmission of nerve impulse
|
Any process that modulates the frequency, rate or extent of transmission of a nerve impulse, the sequential electrochemical polarization and depolarization that travels across the membrane of a neuron in response to stimulation.
|
AGT
|
GO:0051971
|
BP
|
positive regulation of transmission of nerve impulse
|
Any process that activates, maintains or increases the frequency, rate or extent of transmission of a nerve impulse, the sequential electrochemical polarization and depolarization that travels across the membrane of a neuron in response to stimulation.
|
IL6,
ITGA2,
CARTPT,
TNR
|
GO:0051973
|
BP
|
positive regulation of telomerase activity
|
Any process that activates or increases the frequency, rate or extent of telomerase activity, the catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
|
MAP2K7,
KLF4,
GREM1,
DKC1,
TNKS,
TCP1,
MAPK3,
MAPK1,
CTNNB1,
NEK2,
CCT2,
PRKCQ,
PARM1,
NEK7,
ACD,
AURKB,
OBFC1,
POT1,
MAP3K4
|
GO:0051974
|
BP
|
negative regulation of telomerase activity
|
Any process that stops or reduces the activity of the enzyme telomerase, which catalyzes of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
|
TP53,
PPARG,
TERF1,
PIF1,
OBFC1,
POT1
|
GO:0051977
|
BP
|
lysophospholipid transport
|
The directed movement of phospholipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A lysophospholipid is a phospholipid that lacks one of its fatty acyl chains; it is an intermediate formed during digestion of dietary and biliary phospholipids.
|
MFSD2A
|
GO:0051983
|
BP
|
regulation of chromosome segregation
|
Any process that modulates the frequency, rate or extent of chromosome segregation, the process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets.
|
ZNF207,
BUB1,
MKI67,
PUM1,
PUM2,
AURKB,
KIF2C
|
GO:0051984
|
BP
|
positive regulation of chromosome segregation
|
Any process that activates or increases the frequency, rate or extent of chromosome segregation, the process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets.
|
SMC5,
SMC6,
CDC6,
RAD18
|
GO:0051987
|
BP
|
positive regulation of attachment of spindle microtubules to kinetochore
|
Any process that activates or increases the frequency, rate or extent of the attachment of spindle microtubules to the kinetochore.
|
CCNB1,
SIRT2
|
GO:0051988
|
BP
|
regulation of attachment of spindle microtubules to kinetochore
|
Any process that modulates the frequency, rate or extent of the attachment of spindle microtubules to the kinetochore.
|
APC,
NEK2,
CDC42,
SPAG5,
RACGAP1,
ECT2,
KNSTRN
|
GO:0052066
|
BP
|
entry of symbiont into host cell by promotion of host phagocytosis
|
The invasion by an organism of a cell of its host organism by utilizing the host phagocytosis mechanism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
|
ITGAV
|
GO:0052106
|
BP
|
quorum sensing involved in interaction with host
|
The process in which a community of single-celled organisms living in intimate contact with a host organism monitors population density by detecting the concentration of small diffusible signal molecules. The host is defined as the larger of the organisms involved in a symbiotic interaction.
|
SLC22A5
|
GO:0052314
|
BP
|
phytoalexin metabolic process
|
The chemical reactions and pathways involving phytoalexins, any of a range of substances produced by plants as part of their defense response.
|
TH
|
GO:0052405
|
BP
|
negative regulation by host of symbiont molecular function
|
Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of the functional activity of symbiont proteins. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.
|
RAB9A
|
GO:0052547
|
BP
|
regulation of peptidase activity
|
Any process that modulates the frequency, rate or extent of peptidase activity, the hydrolysis of peptide bonds within proteins.
|
CAV1
|
GO:0052548
|
BP
|
regulation of endopeptidase activity
|
Any process that modulates the frequency, rate or extent of endopeptidase activity, the endohydrolysis of peptide bonds within proteins.
|
NRDC,
FURIN,
PSMA3,
PSMB8,
ATP13A2
|
GO:0052567
|
BP
|
response to defense-related host reactive oxygen species production
|
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of reactive oxygen species produced as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
|
TUSC2
|
GO:0052651
|
BP
|
monoacylglycerol catabolic process
|
The chemical reactions and pathways resulting in the breakdown of monoacylglycerol, any ester of glycerol in which any one of its hydroxyl groups has been acylated with a fatty acid, the other being non-esterified.
|
ABHD12
|
GO:0052695
|
BP
|
cellular glucuronidation
|
The modification of an organic chemical by the conjugation of glucuronic acid. The substances resulting from glucuronidation are known as glucuronosides (or glucuronides) and are often much more water-soluble than the non-glucuronic acid-containing precursor.
|
UGT2B4,
UGT2A3,
ABHD10
|
GO:0052696
|
BP
|
flavonoid glucuronidation
|
The modification of a flavonoid by the conjugation of glucuronic acid. The resultant flavonoid glucuronosides are often much more water-soluble than the precursor.
|
UGT2B4,
UGT2A3
|
GO:0055001
|
BP
|
muscle cell development
|
The process whose specific outcome is the progression of a muscle cell over time, from its formation to the mature structure. Muscle cell development does not include the steps involved in committing an unspecified cell to the muscle cell fate.
|
AXIN1,
KDM1A,
NFATC4,
SGCD,
MEGF10,
SGCZ
|
GO:0055002
|
BP
|
striated muscle cell development
|
The process whose specific outcome is the progression of a striated muscle cell over time, from its formation to the mature structure. Striated muscle cells contain fibers that are divided by transverse bands into striations, and cardiac and skeletal muscle are types of striated muscle.
|
SDC1
|
GO:0055003
|
BP
|
cardiac myofibril assembly
|
The process whose specific outcome is the progression of the cardiac myofibril over time, from its formation to the mature structure. A cardiac myofibril is a myofibril specific to cardiac muscle cells.
|
OBSL1,
PDGFRB,
PDGFRA,
ACTC1,
TTN
|
GO:0055005
|
BP
|
ventricular cardiac myofibril assembly
|
The process whose specific outcome is the progression of the ventricular cardiac myofibril over time, from its formation to the mature structure. A cardiac myofibril is a myofibril specific to cardiac muscle cells.
|
MEF2A,
PROX1
|
GO:0055007
|
BP
|
cardiac muscle cell differentiation
|
The process in which a cardiac muscle precursor cell acquires specialized features of a cardiac muscle cell. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction.
|
ARID1A,
ITGB1,
BMP2,
BMP4,
CALR,
SOX6,
SIK1,
NRG1,
AKAP13,
PROX1,
GATA6,
CACYBP,
NOX4
|
GO:0055008
|
BP
|
cardiac muscle tissue morphogenesis
|
The process in which the anatomical structures of cardiac muscle tissue are generated and organized.
|
BMP2,
NOTCH1,
ACTC1,
ANKRD1,
TTN
|
GO:0055009
|
BP
|
atrial cardiac muscle tissue morphogenesis
|
The process in which the anatomical structure of cardiac atrium muscle is generated and organized.
|
BMP10,
WNT2,
PROX1,
PITX2
|
GO:0055010
|
BP
|
ventricular cardiac muscle tissue morphogenesis
|
The process in which the anatomical structures of cardiac ventricle muscle is generated and organized.
|
SMAD7,
BMP10,
TGFB1,
TPM1,
COL11A1,
TNNI3,
FGFR2,
TGFBR3,
FOXC1,
PROX1,
PKP2
|
GO:0055012
|
BP
|
ventricular cardiac muscle cell differentiation
|
The process in which a relatively unspecialized cell acquires specialized features of a ventricular cardiac muscle cell. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. The ventricle is the part of the heart that pumps blood out of the organ.
|
MEF2C
|
GO:0055013
|
BP
|
cardiac muscle cell development
|
The process whose specific outcome is the progression of a cardiac muscle cell over time, from its formation to the mature state.
|
ACTN2,
HNRNPU,
SGCB
|
GO:0055015
|
BP
|
ventricular cardiac muscle cell development
|
The process whose specific outcome is the progression of a ventricular cardiac muscle cell over time, from its formation to the mature state. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. The ventricle is the part of the heart that pumps blood out of the organ.
|
BMP10,
LMNA,
CDK1,
CCNB1,
PITX2
|
GO:0055017
|
BP
|
cardiac muscle tissue growth
|
The increase in size or mass of a cardiac muscle, where the increase in size or mass has the specific outcome of the progression of the organism over time from one condition to another.
|
HEG1
|
GO:0055020
|
BP
|
positive regulation of cardiac muscle fiber development
|
Any process that activates, maintains or increases the frequency, rate or extent of cardiac muscle fiber development.
|
BMP4
|
GO:0055025
|
BP
|
positive regulation of cardiac muscle tissue development
|
Any process that activates, maintains or increases the frequency, rate or extent of cardiac muscle tissue development.
|
CREB1,
ERBB3
|
GO:0055059
|
BP
|
asymmetric neuroblast division
|
The process resulting in the physical partitioning and separation of a neuroblast into two daughter cells with different developmental potentials.
|
TEAD3
|
GO:0055062
|
BP
|
phosphate ion homeostasis
|
Any process involved in the maintenance of an internal steady state of phosphate ions within an organism or cell.
|
SFRP4
|
GO:0055064
|
BP
|
chloride ion homeostasis
|
Any process involved in the maintenance of an internal steady state of chloride ions within an organism or cell.
|
CA12
|
GO:0055065
|
BP
|
metal ion homeostasis
|
Any process involved in the maintenance of an internal steady state of metal ions within an organism or cell.
|
SLC7A8
|
GO:0055069
|
BP
|
zinc ion homeostasis
|
Any process involved in the maintenance of an internal steady state of zinc ions within an organism or cell.
|
PARK2,
MT3,
ATP13A2
|
GO:0055070
|
BP
|
copper ion homeostasis
|
Any process involved in the maintenance of an internal steady state of copper ions within an organism or cell.
|
XIAP,
COMMD1
|
GO:0055072
|
BP
|
iron ion homeostasis
|
Any process involved in the maintenance of an internal steady state of iron ions within an organism or cell.
|
TF,
FTL,
MFI2,
HMOX1,
SLC11A1,
B2M,
PICALM,
HFE,
STEAP4,
SFXN4,
TMPRSS6,
EPAS1,
BDH2,
SFXN3,
SFXN1,
SLC25A37,
TFR2
|
GO:0055073
|
BP
|
cadmium ion homeostasis
|
Any process involved in the maintenance of an internal steady state of cadmium ions within an organism or cell.
|
MT3
|
GO:0055074
|
BP
|
calcium ion homeostasis
|
Any process involved in the maintenance of an internal steady state of calcium ions within an organism or cell.
|
TNFSF11,
CYP27B1,
CAV1,
CCDC47,
TRPV6,
SEPN1,
KL
|
GO:0055075
|
BP
|
potassium ion homeostasis
|
Any process involved in the maintenance of an internal steady state of potassium ions within an organism or cell.
|
CYP11B2,
KCNH2
|
GO:0055078
|
BP
|
sodium ion homeostasis
|
Any process involved in the maintenance of an internal steady state of sodium ions within an organism or cell.
|
CYP11B2,
SCNN1A,
SCNN1G
|
GO:0055085
|
BP
|
transmembrane transport
|
The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other
|
SLC22A23,
SLC33A1,
ABCD4,
ABCC4,
ABCC5,
ABCA8,
APOA1,
SLC25A5,
EIF2S1,
BCL2,
SLC25A4,
CFTR,
SLC25A16,
MAL,
AZGP1,
ABCD3,
SLC6A1,
ABCC1,
GJA5,
EIF2S3,
VDAC2,
PEX3,
ABCE1,
SEC61A1,
RNASEL,
SLC18A2,
SLC10A7,
SLC14A1,
KCNJ11,
RALBP1,
SLC15A2,
NDUFAF6,
PDZD11,
MFSD14B,
ABCC10,
SLC18B1,
SLC23A3,
SV2A,
SV2B,
SLC16A14,
SLC16A9,
SLC44A2,
ABCA6,
SLC44A3,
SLC15A4,
MFSD2A,
SLC43A3,
SLC44A5,
ABCF1,
NUP35,
MFSD8,
SLC25A43,
SLC44A1,
SLC5A11,
ABCA5,
SLC25A36,
SLC47A1,
SLC41A3,
SLC25A44,
SLC41A2,
MFSD14A,
PANX2,
SLC46A2,
SLC25A18,
ABCG8,
TMEM245,
MFSD1,
SLC25A19,
ANKH,
MRS2,
ABCB6,
ABCB10,
ADD3,
FLVCR2,
VDAC3
|
GO:0055088
|
BP
|
lipid homeostasis
|
Any process involved in the maintenance of an internal steady state of lipid within an organism or cell.
|
ACOX3,
PPARG,
ACADSB,
ACADVL,
NR1H3,
NR1D2,
USF2,
PNPLA5,
PNPLA2,
ACOX2,
PKP2,
PNPLA3,
IRS2
|
GO:0055089
|
BP
|
fatty acid homeostasis
|
Any process involved in the maintenance of an internal steady state of fatty acid within an organism or cell.
|
INS,
APOE,
XBP1,
POLD1,
PRKAA2,
DGAT2,
NR1H4,
GPAM
|
GO:0055090
|
BP
|
acylglycerol homeostasis
|
Any process involved in the maintenance of an internal steady state of acylglycerol within an organism or cell.
|
APOA5
|
GO:0055091
|
BP
|
phospholipid homeostasis
|
Any process involved in the maintenance of an internal steady state of phospholipid within an organism or cell.
|
ABCA1,
APOA1,
FABP3,
GPAM,
LIPG
|
GO:0055092
|
BP
|
sterol homeostasis
|
Any process involved in the maintenance of an internal steady state of sterol within an organism or cell.
|
XBP1,
NR1H3
|
GO:0055093
|
BP
|
response to hyperoxia
|
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating increased oxygen tension.
|
COL1A1,
CYP1A1,
PDGFRB,
CDK4,
CDKN1A,
POLG,
BNIP3,
HDAC1,
HDAC2
|
GO:0055094
|
BP
|
response to lipoprotein particle
|
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipoprotein particle stimulus.
|
HMGCS1
|
GO:0055096
|
BP
|
low-density lipoprotein particle mediated signaling
|
A series of molecular signals mediated by the detection of low-density lipoprotein particle.
|
CD36,
CDH13
|
GO:0055098
|
BP
|
response to low-density lipoprotein particle
|
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a low-density lipoprotein particle stimulus.
|
ABCA1,
PPARG,
SREBF2
|
GO:0055099
|
BP
|
response to high density lipoprotein particle
|
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a high density lipoprotein particle stimulus.
|
ADAM17
|
GO:0055108
|
BP
|
Golgi to transport vesicle transport
|
The directed movement of proteins from the Golgi to a transport vesicle. Continuously secreted proteins are sorted into transport vesicles that fuse with the plasma membrane, releasing their contents by exocytosis.
|
ARF1
|
GO:0055114
|
BP
|
oxidation-reduction process
|
A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.
|
DHRS12,
SH3PXD2B,
AGPS,
PLOD2,
SCD,
UTY,
CCS,
HSD17B6,
KMO,
ABCC4,
P4HA2,
CYP27B1,
KDM6A,
CYB5B,
CYP26A1,
PHGDH,
PRODH,
AKR7A2,
KDM1A,
FADS1,
UGDH,
AOC2,
CREG1,
SC5D,
ALDH1L1,
DHRS3,
TM7SF2,
ALDH1A2,
MICAL2,
KDM4B,
H6PD,
DUS4L,
CRYZL1,
AIFM1,
FADS2,
CH25H,
CYB5A,
LDHA,
DHFR,
CYB5R3,
GSR,
F8,
FTH1,
HMGCR,
SOD2,
CYP1A1,
CYBB,
CYP17A1,
CYP11A1,
MPO,
CYP2E1,
TH,
LDHB,
UQCRH,
SOD3,
CYP3A4,
CYP21A2,
QDPR,
ALOX5,
FDX1,
TXN,
MGST1,
CYP2D6,
G6PD,
CYP2A6,
CYP19A1,
MTHFD1,
CYP2C9,
BMP2,
BCKDHA,
P4HA1,
MTHFD2,
HSD3B1,
HSD17B1,
TYR,
UQCRB,
AKR1B1,
HPGD,
CYP11B1,
NQO1,
ALOX15,
NQO2,
CBR1,
SRD5A1,
PAM,
CYP11B2,
VCAM1,
NCF2,
CYP2B6,
MAOA,
BCKDHB,
GPX3,
PTGS1,
ME2,
RRM1,
CHM,
CHML,
HSD3B2,
MAOB,
LOX,
HSD11B1,
KDM5A,
NOS3,
PRDX6,
BLVRB,
PDIA3,
SDHA,
GDI1,
SRD5A2,
RRM2,
FMO4,
UQCRC1,
HIBADH,
PRDX2,
PTGS2,
CBS,
GLRX,
CPOX,
GMPR,
GPX4,
HSD17B2,
FDFT1,
SNCA,
ADH7,
AKR1C3,
MTHFR,
GPD2,
ALDH1A3,
XDH,
ALDH3B2,
ALDH9A1,
FASN,
ALDH7A1,
GLUD2,
GDI2,
ALDH3A2,
PGD,
AKR1C2,
HCCS,
ALDH18A1,
GFER,
CTBP2,
HSD17B7,
SESN3,
GSTO1,
HSD11B2,
MRPS36,
SORD,
DHODH,
ALDH6A1,
PLOD1,
AKR1C1,
AOX1,
PRDX1,
PIGF,
CRYZ,
LOXL1,
ASPH,
DPYD,
PRDX4,
SQLE,
PDIA5,
PTGR1,
NCF4,
DHCR24,
JMJD1C,
NSDHL,
MSMO1,
PTGIS,
CYP1B1,
ME3,
CYP51A1,
AOC3,
CDO1,
TXNRD1,
ALDH1L2,
GLYR1,
HSD17B12,
PYCRL,
CYBRD1,
TECRL,
ASPHD1,
MARC1,
STEAP4,
ASPHD2,
JMJD6,
FDX1L,
OGFOD3,
MTHFD1L,
MOXD1,
DHRS13,
CYP2R1,
HSDL2,
KDM7A,
QSOX2,
FA2H,
AAED1,
CYP2U1,
DCXR,
SCD5,
ERO1B,
MINA,
P3H2,
TPH2,
ADHFE1,
DNAJC10,
MSRB3,
ALDH16A1,
RDH10,
ZADH2,
OXR1,
CYB561D1,
SUMF1,
RDH13,
HSD17B11,
CYP2W1,
RDH11,
ENOX1,
MICAL1,
GPX8,
STAB2,
RTN4IP1,
DIO2,
HGD,
KIAA1191,
ERO1A,
HPDL,
LOXL4,
FAR2,
DHRS1,
NOX5,
HHIP,
GPX7,
SDHC,
HSD17B10,
TXN2,
DHRS9,
VKORC1,
HEPH,
AIFM2,
FAM213A,
ALKBH7,
DHRS4,
DOHH,
HTATIP2,
ADI1,
MECR,
C1orf43,
NMES1,
TMX4,
SH3BGRL3,
ALDH8A1,
HSD3B7,
GSTO2,
EGLN3,
MTHFD2L,
CYP3A43,
NOX4,
CYP26B1,
DUOX2,
DUOX1,
GLRX2,
STAB1,
SEPN1,
PIPOX,
DHCR7,
GRHPR,
AASS,
MIOX,
KDM5B,
PCYOX1,
DMGDH,
OSGIN1,
SARDH,
CYP8B1,
HIGD1A,
KDM2A,
GSTK1,
CRYL1,
DHRS7,
LOXL2,
SESN1
|
GO:0055117
|
BP
|
regulation of cardiac muscle contraction
|
Any process that modulates the frequency, rate or extent of cardiac muscle contraction.
|
SMAD7,
BMP10,
PRKACA,
ADRA1B,
GJA5,
CALM2,
ANK2,
RYR2,
P2RX4,
EHD3
|
GO:0055118
|
BP
|
negative regulation of cardiac muscle contraction
|
Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle contraction.
|
PDE5A,
ADORA1,
PIK3CG
|
GO:0055119
|
BP
|
relaxation of cardiac muscle
|
The process in which the extent of cardiac muscle contraction is reduced.
|
PDE5A,
ATP1B1,
ATP2A2,
PLN,
GSTM2,
RGS2,
ATP1A2,
CAMK2D,
P2RX4
|
GO:0055123
|
BP
|
digestive system development
|
The process whose specific outcome is the progression of the digestive system over time, from its formation to the mature structure. The digestive system is the entire structure in which digestion takes place. Digestion is all of the physical, chemical, and biochemical processes carried out by multicellular organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism.
|
CDKN1C
|
GO:0055129
|
BP
|
L-proline biosynthetic process
|
The chemical reactions and pathways resulting in the formation of L-proline, an L-enantiomer of a chiral, cyclic, nonessential alpha-amino acid found in peptide linkage in proteins.
|
ALDH18A1,
PYCRL
|
GO:0060004
|
BP
|
reflex
|
An automatic response to a stimulus beginning with a nerve impulse from a receptor and ending with the action of an effector such as a gland or a muscle. Signaling never reaches a level of consciousness.
|
SATB1
|
GO:0060005
|
BP
|
vestibular reflex
|
A reflex process in which a response to an angular or linear acceleration stimulus begins with an afferent nerve impulse from a receptor in the inner ear and ends with the compensatory action of eye muscles. Signaling never reaches a level of consciousness.
|
NR4A3
|
GO:0060008
|
BP
|
Sertoli cell differentiation
|
The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a Sertoli cell. A Sertoli cell is a supporting cell projecting inward from the basement membrane of seminiferous tubules.
|
TCF21,
SOX9,
NR0B1
|
GO:0060009
|
BP
|
Sertoli cell development
|
The process whose specific outcome is the progression of a Sertoli cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a Sertoli cell fate.
|
CST3,
NTRK1,
SDC1,
ATRX,
SOX9,
HSD17B4,
SOX8
|
GO:0060011
|
BP
|
Sertoli cell proliferation
|
The multiplication or reproduction of Sertoli cells, resulting in the expansion of the Sertoli cell population. A Sertoli cell is a supporting cell projecting inward from the basement membrane of seminiferous tubules.
|
FSHB,
ACVR2A,
BAX,
BCL2L2
|
GO:0060012
|
BP
|
synaptic transmission, glycinergic
|
The process of communication from a neuron to another neuron across a synapse using the neurotransmitter glycine.
|
GLRB
|
GO:0060013
|
BP
|
righting reflex
|
A reflex process in which an animal immediately tries to turn over after being placed in a supine position.
|
FOXP2,
ALDH1A3,
GLRB,
USP46
|
GO:0060014
|
BP
|
granulosa cell differentiation
|
The process in which a relatively unspecialized cell acquires the specialized features of a granulosa cell, a supporting cell for the developing female gamete in the ovary of mammals.
|
FOXL2
|
GO:0060016
|
BP
|
granulosa cell development
|
The process whose specific outcome is the progression of a granulosa cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a granulosa cell fate.
|
BMP15
|
GO:0060017
|
BP
|
parathyroid gland development
|
The process whose specific outcome is the progression of the parathyroid gland over time, from its formation to the mature structure. The parathyroid gland is an organ specialised for secretion of parathyroid hormone.
|
HOXA3,
TBX1,
TGFBR1,
CRKL
|
GO:0060018
|
BP
|
astrocyte fate commitment
|
The commitment of a cells to a specific astrocyte fate and its restriction to develop only into an astrocyte.
|
TAL1,
SOX9,
SOX8
|
GO:0060019
|
BP
|
radial glial cell differentiation
|
The process in which neuroepithelial cells of the neural tube give rise to radial glial cells, specialized bipotential progenitors cells of the brain. Differentiation includes the processes involved in commitment of a cell to a specific fate.
|
CDH2,
STAT3
|
GO:0060020
|
BP
|
Bergmann glial cell differentiation
|
The process in which neuroepithelial cells of the neural tube give rise to Brgmann glial cells, specialized bipotential progenitors cells of the cerebellum. Differentiation includes the processes involved in commitment of a cell to a specific fate.
|
PLPP3,
VIM,
MAPK3,
MAPK1,
MAP2K1,
PTPN11
|
GO:0060021
|
BP
|
palate development
|
The biological process whose specific outcome is the progression of the palate from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure. The palate is the partition that separates the nasal and oral cavities.
|
INSIG1,
SNAI2,
TCF21,
LRP6,
DHRS3,
GDF11,
INHBA,
GLI3,
SKI,
COL11A2,
EPHB2,
BMPR1A,
TGFBR1,
TGFBR2,
WNT5A,
DLX5,
TGFB2,
TGFBR3,
MEF2C,
SOS1,
NPRL3,
SMAD4,
ACVR2B,
ARID5B,
TWIST1,
SMAD2,
BNC2,
FRAS1,
BBS7,
OSR1,
ANP32B,
CSRNP1,
PYGO2,
PAK1IP1,
CHD7
|
GO:0060022
|
BP
|
hard palate development
|
The biological process whose specific outcome is the progression of the hard palate from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. The hard palate is the anterior portion of the palate consisting of bone and mucous membranes.
|
DLG1,
MMP25
|
GO:0060023
|
BP
|
soft palate development
|
The biological process whose specific outcome is the progression of the soft palate from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. The soft palate is the posterior portion of the palate extending from the posterior edge of the hard palate.
|
TBX1,
COL11A2,
TSHZ1
|
GO:0060024
|
BP
|
rhythmic synaptic transmission
|
Any process involved in the generation of rhythmic, synchronous synaptic inputs in a neural circuit.
|
PTEN
|
GO:0060025
|
BP
|
regulation of synaptic activity
|
Any process that modulates the frequency, rate or extent of synaptic activity, the controlled release of neurotransmitters into the synaptic cleft and their subsequent detection by a postsynaptic cell.
|
MEF2C
|
GO:0060026
|
BP
|
convergent extension
|
The morphogenetic process in which an epithelium narrows along one axis and lengthens in a perpendicular axis.
|
LRP6,
PTK7
|
GO:0060027
|
BP
|
convergent extension involved in gastrulation
|
The morphogenetic process in which an epithelium narrows along one axis and lengthens in a perpendicular axis usually resulting in the formation of the three primary germ layers, ectoderm, mesoderm and endoderm.
|
NPHP3,
MKKS
|
GO:0060028
|
BP
|
convergent extension involved in axis elongation
|
The morphogenetic process in which an epithelium narrows along one axis and lengthens in a perpendicular axis contributing to the lengthening of the axis of an organism.
|
WNT5A,
TRIM28
|
GO:0060029
|
BP
|
convergent extension involved in organogenesis
|
The morphogenetic process in which an epithelium narrows along one axis and lengthens in a perpendicular axis contribution to the shaping of an organ.
|
WNT5A
|
GO:0060032
|
BP
|
notochord regression
|
The developmental process in which the stucture of the notochord is destroyed in an embryo.
|
GLI2
|
GO:0060033
|
BP
|
anatomical structure regression
|
The developmental process in which an anatomical stucture is destroyed as a part of its normal progression.
|
LRP5,
CD248
|
GO:0060037
|
BP
|
pharyngeal system development
|
The process whose specific outcome is the progression of the pharyngeal system over time, from its formation to the mature structure. The pharyngeal system is a transient embryonic complex that is specific to vertebrates. It comprises the pharyngeal arches, bulges of tissues of mesoderm and neural crest derivation through which pass nerves and pharyngeal arch arteries. The arches are separated internally by pharyngeal pouches, evaginations of foregut endoderm, and externally by pharyngeal clefts, invaginations of surface ectoderm. The development of the system ends when the stucture it contributes to are forming: the thymus, thyroid, parathyroids, maxilla, mandible, aortic arch, cardiac outflow tract, external and middle ear.
|
TBX1,
PLXNA2,
TGFBR1,
ECE1,
ACVR1,
PTCH1
|
GO:0060038
|
BP
|
cardiac muscle cell proliferation
|
The expansion of a cardiac muscle cell population by cell division.
|
BMP10,
PRKAR1A,
NOTCH1,
TGFB2,
TGFBR3,
FOXC1,
SMAD1,
TENM4,
NDRG4
|