GO:0014029

BP

neural crest formation

The formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation procedes.

LRP6

GO:0014031

BP

mesenchymal cell development

The process aimed at the progression of a mesenchymal cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell.

BCL2, NOTCH1, FOXC1, HEYL

GO:0014032

BP

neural crest cell development

The process aimed at the progression of a neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell.

SNAI2, ALDH1A2, EDN1, EDNRA, BMPR1A, SOX9, NRG1, FOXC1, RDH10

GO:0014033

BP

neural crest cell differentiation

The process in which a relatively unspecialized cell acquires specialized features of a neural crest cell.

LRP6, HTR2B, MEF2C, SMAD4

GO:0014034

BP

neural crest cell fate commitment

The process in which a cell becomes committed to become a neural crest cell.

SFRP1

GO:0014037

BP

Schwann cell differentiation

The process in which a relatively unspecialized cell acquires the specialized features of a Schwann cell. Schwann cells are found in the peripheral nervous system, where they insulate neurons and axons, and regulate the environment in which neurons function.

EGR2, ERBB3, GPC1

GO:0014038

BP

regulation of Schwann cell differentiation

Any process that modulates the frequency, rate or extent of Schwann cell differentiation.

CDK1

GO:0014040

BP

positive regulation of Schwann cell differentiation

Any process that activates or increases the frequency, rate or extent of Schwann cell differentiation.

RELA, DICER1

GO:0014041

BP

regulation of neuron maturation

Any process that modulates the frequency, rate or extent of neuron maturation, the process leading to the attainment of the full functional capacity of a neuron. This process is independent of morphogenetic change.

RAC3, RAC1

GO:0014042

BP

positive regulation of neuron maturation

Any process that activates or increases the frequency, rate or extent of neuron maturation.

OPA1, BCL2

GO:0014043

BP

negative regulation of neuron maturation

Any process that stops, prevents, or reduces the frequency, rate or extent of neuron maturation.

GSK3B

GO:0014044

BP

Schwann cell development

The process aimed at the progression of a Schwann cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. Schwann cells are found in the peripheral nervous system, where they insulate neurons and axons, and regulate the environment in which neurons function.

CDK5, MED12

GO:0014047

BP

glutamate secretion

The controlled release of glutamate by a cell. The glutamate is the most abundant excitatory neurotransmitter in the nervous system.

GLS, SYT1, SLC1A3, SLC1A2, SLC1A6, SNAP25, STXBP1, VAMP2, APBA1, NTRK2, TRPV1

GO:0014048

BP

regulation of glutamate secretion

Any process that modulates the frequency, rate or extent of the controlled release of glutamate.

SNCA

GO:0014049

BP

positive regulation of glutamate secretion

Any process that activates or increases the frequency, rate or extent of the controlled release of glutamate.

CCK, DPYSL2

GO:0014050

BP

negative regulation of glutamate secretion

Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of glutamate.

TRH, ADORA1, NPY5R, HRH3

GO:0014051

BP

gamma-aminobutyric acid secretion

The regulated release of gamma-aminobutyric acid by a cell or a tissue. The gamma-aminobutyric acid is the principal inhibitory neurotransmitter in the brain but is also found in several extraneural tissues.

APBA1

GO:0014053

BP

negative regulation of gamma-aminobutyric acid secretion

Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of gamma-aminobutyric acid.

ABAT

GO:0014054

BP

positive regulation of gamma-aminobutyric acid secretion

Any process that activates or increases the frequency, rate or extent of the regulated release of gamma-aminobutyric acid.

TRH, SLC6A1

GO:0014059

BP

regulation of dopamine secretion

Any process that modulates the frequency, rate or extent of the regulated release of dopamine.

PARK2, DRD2, SNCA

GO:0014061

BP

regulation of norepinephrine secretion

Any process that modulates the frequency, rate or extent of the regulated release of norepinephrine.

AGT, CHRNA7, HRH3

GO:0014063

BP

negative regulation of serotonin secretion

Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of serotonin.

MAOB, LILRB1, HRH3

GO:0014065

BP

phosphatidylinositol 3-kinase signaling

A series of reactions within the signal-receiving cell, mediated by the intracellular phosphatidylinositol 3-kinase (PI3K). Many cell surface receptor linked signaling pathways signal through PI3K to regulate numerous cellular functions.

PIK3CD, ERBB2, IGF1, EDN1, IGF1R, ERBB3, PIK3R1, LTK, IRS1, HTR2B, PIK3CB, PIK3CG, TYRO3, C1QBP, ZFP36L1, PREX2, SIRT2

GO:0014066

BP

regulation of phosphatidylinositol 3-kinase signaling

Any process that modulates the frequency, rate or extent of signal transduction mediated by the phosphatidylinositol 3-kinase cascade.

PIK3CD, EREG, PIP5K1B, PIP5K1C, FGF18, FGF19, EGFR, PDGFB, PDGFA, ERBB2, FYN, FGF2, PDGFRB, KIT, CD28, FGFR1, VAV1, PDGFRA, KITLG, FGF7, FGFR2, ERBB3, MAPK3, PIK3R1, MAPK1, FGF9, AKT1, BTC, IRS1, PIK3CA, PIK3CB, IER3, GRB2, PIP4K2B, NRG1, PTPN11, PPP2R5C, GAB1, PPP2R5B, ERBB4, FRS2, HBEGF, KL, FBXL2, IRS2

GO:0014067

BP

negative regulation of phosphatidylinositol 3-kinase signaling

Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the phosphatidylinositol 3-kinase cascade.

KLF4, STAMBP, SERPINE2, TSC2, PTEN, TWIST1

GO:0014068

BP

positive regulation of phosphatidylinositol 3-kinase signaling

Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the phosphatidylinositol 3-kinase cascade.

HAX1, JAK2, F2, AGT, PDGFB, GH1, INS, PDGFA, IGF1, FYN, DCN, PDGFRB, FGR, KIT, CD28, FGFR1, CCL5, HGF, HCLS1, PDGFRA, ERBB3, FSHR, F2R, LEP, SOX9, F2RL1, TGFB2, NRG1, TEK, PPARD, PTK2, IL18, ERBB4, ANGPT1, NTRK2, SERPINA12, UNC5B, MYDGF, GPER1, PDGFD, PDGFC

GO:0014070

BP

response to organic cyclic compound

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus.

ACACB, PTGES, ANGPT2, ABCC4, AMH, ICAM1, CDK1, EPHX1, LYN, G6PD, ATF1, COMT, ABCD3, ACSL1, NAMPT, MKI67, MMP14, CPT1A, LUM, BTG2, CD83, NEDD8, DUSP6, LONP2, SFRP1, PLIN2, TXN2

GO:0014074

BP

response to purine-containing compound

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a purine-containing compound stimulus.

ADSS, SLC6A1, HMGCS1, AACS

GO:0014075

BP

response to amine

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amine stimulus. An amine is a compound formally derived from ammonia by replacing one, two or three hydrogen atoms by hydrocarbyl groups.

CDK1, NME1, ITGA2, CAD, HNMT

GO:0014706

BP

striated muscle tissue development

The process whose specific outcome is the progression of a striated muscle over time, from its formation to the mature structure. Striated muscle contain fibers that are divided by transverse bands into striations, and cardiac and skeletal muscle are types of striated muscle. Skeletal muscle myoblasts fuse to form myotubes and eventually multinucleated muscle fibers. The fusion of cardiac cells is very rare and can only form binucleate cells.

EYA2, IFRD1

GO:0014707

BP

branchiomeric skeletal muscle development

The process whose specific outcome is the progression of the branchiomeric skeletal muscle over time, from its formation to the mature structure. The branchiomeric muscle is derived from cranial mesoderm and controls facial expression, pharyngeal and laryngeal function, operating the jaw. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle. Branchiomeric muscles of mammals correspond to the gill musculature of fish.

TCF21

GO:0014718

BP

positive regulation of satellite cell activation involved in skeletal muscle regeneration

Any process that activates, maintains or increases the frequency, rate or extent of activation of satellite cell involved in skeletal muscle regeneration. The activation of satellite cell is the process that initiates satellite cell division by causing it to move from quiescence to the G1 stage of the cell cycle. The cell swells and there are a number of other small changes. The cells then start to divide. Following cell division the cells will differentiate.

SOX15, CAPN3

GO:0014719

BP

skeletal muscle satellite cell activation

The change of a skeletal muscle satellite cell from a mitotically quiescent to a mitotically active state following exposure to some activating factor such as a cellular or soluble ligand. In adult muscle, satellite cells become activated to divide and differentiate in response to muscle damage.

MEGF10

GO:0014722

BP

regulation of skeletal muscle contraction by calcium ion signaling

Any process that modulates the frequency, rate or extent of skeletal muscle contraction by changing the calcium ion signals that trigger contraction.

DMPK

GO:0014732

BP

skeletal muscle atrophy

A process, occurring in skeletal muscle, that is characterized by a decrease in protein content, fiber diameter, force production and fatigue resistance in response to different conditions such as starvation, aging and disuse.

MSTN, CFLAR, PPARGC1A

GO:0014736

BP

negative regulation of muscle atrophy

Any process that stops, prevents, or reduces the frequency, rate, or extent of muscle atrophy.

NOL3

GO:0014740

BP

negative regulation of muscle hyperplasia

Any process that stops, prevents, or reduces the frequency, rate, or extent of muscle hyperplasia.

KLF4, NOS3

GO:0014741

BP

negative regulation of muscle hypertrophy

Any process that stops, prevents, or reduces the frequency, rate, or extent of muscle hypertrophy.

MSTN

GO:0014805

BP

smooth muscle adaptation

Any process in which smooth muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities.

IL1B

GO:0014806

BP

smooth muscle hyperplasia

A process, occurring in smooth muscle, in which there is an increase in cell number by cell division, often leading to an increase in the size of an organ.

HMOX1, NOS3

GO:0014807

BP

regulation of somitogenesis

Any process that modulates the frequency, rate or extent of somitogenesis.

NOTCH1

GO:0014808

BP

release of sequestered calcium ion into cytosol by sarcoplasmic reticulum

The process in which the release of sequestered calcium ion by sarcoplasmic reticulum into cytosol occurs via calcium release channels.

NOL3, CCL3, RYR2

GO:0014809

BP

regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion

Any process that modulates the frequency, rate or extent of skeletal muscle contraction via the regulation of the release of sequestered calcium ion by sarcoplasmic reticulum into cytosol. The sarcoplasmic reticulum is the endoplasmic reticulum of striated muscle, specialised for the sequestration of calcium ions that are released upon receipt of a signal relayed by the T tubules from the neuromuscular junction.

DMD, GSTM2

GO:0014810

BP

positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion

Any process that activates, maintains or increases the frequency, rate or extent of skeletal muscle contraction via the regulation of the release of sequestered calcium ion by sarcoplasmic reticulum into cytosol. The sarcoplasmic reticulum is the endoplasmic reticulum of striated muscle, specialised for the sequestration of calcium ions that are released upon receipt of a signal relayed by the T tubules from the neuromuscular junction.

GSTO1

GO:0014816

BP

skeletal muscle satellite cell differentiation

The process in which a relatively unspecialized cell acquires specialized features of a satellite cell.

MEGF10, SEPN1

GO:0014819

BP

regulation of skeletal muscle contraction

Any process that modulates the frequency, rate or extent of skeletal muscle contraction.

DMD

GO:0014820

BP

tonic smooth muscle contraction

A process in which force is generated within tonic smooth muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. In the tonic smooth muscle, the muscle contraction occurs without an ordered sarcomeric structure. Tonic smooth muscle contraction occurs as a sustained continuous contraction.

MYLK

GO:0014823

BP

response to activity

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an activity stimulus.

ANGPT2, BGLAP, NTRK1, EDN1, CDK1, TH, HSPD1, CCL2, ALAD, CREB1, BMP6, IL10, UQCRC1, PCK1, LEP, GCLC, GCLM, STAR, OXCT1, UCP3, PRKDC, HSF1, PPARD, ADIPOQ, HADH, TPH2, DNMT3B, MYH2, HDAC5, MYH4

GO:0014824

BP

artery smooth muscle contraction

A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the artery. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The artery is a vessel carrying blood away from the heart.

AGT, EDN1, EDN2, EDNRA, BBS2, MKKS

GO:0014826

BP

vein smooth muscle contraction

A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the vein. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The vein is a vessel carrying blood away from the capillary beds.

EDN1, EDN2

GO:0014827

BP

intestine smooth muscle contraction

A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the intestine. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The intestine is the section of the alimentary canal from the stomach to the anal canal. It includes the large intestine and small intestine.

HTR2B, PTGER3

GO:0014829

BP

vascular smooth muscle contraction

A process, occurring in the vascular tissue, whereby actin/myosin complex activity generates force through ATP hydrolysis resulting in a change in smooth muscle geometry. This process is always coupled to chemo-mechanical energy conversion.

PIK3C2A, RAP1GDS1, ACTA2

GO:0014834

BP

skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration

Any process by which the number of skeletal muscle satellite cells in a skeletal muscle is maintained during muscle regeneration. There are at least three mechanisms by which this is achieved. Skeletal muscle satellite stem cell asymmetric division ensures satellite stem cell numbers are kept constant. Symmetric division of these cells amplifies the number of skeletal muscle satellite stem cells. Some adult skeletal muscle myoblasts (descendants of activated satellite cells) can develop back into quiescent satellite cells, replenishing the overall pool of satellite cells.

FZD7, IGF1, EZH2, SEPN1

GO:0014835

BP

myoblast differentiation involved in skeletal muscle regeneration

The process in which a relatively unspecialized satellite cell acquires specialized features of a myoblast. This occurs as part of skeletal muscle regeneration. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.

MAPK14

GO:0014839

BP

myoblast migration involved in skeletal muscle regeneration

The process in which a myoblast migrates along an entire fiber to the site of injury. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.

ANXA1

GO:0014841

BP

skeletal muscle satellite cell proliferation

The multiplication or reproduction of satellite cells, resulting in the expansion of the cell population. Satellite cells are quiescent cells that are located between the basal lamina and the plasmalemma of the muscle fiber, which are the main contributors to postnatal muscle growth. In adult muscle, satellite cells become activated to divide and differentiate in response to muscle damage.

MEGF10

GO:0014842

BP

regulation of skeletal muscle satellite cell proliferation

Any process that modulates the frequency, rate or extent of skeletal muscle satellite cell proliferation.

CFLAR, PPARD, ANGPT1, PAXBP1

GO:0014843

BP

growth factor dependent regulation of skeletal muscle satellite cell proliferation

Any process that modulates the frequency, rate or extent of satellite cell proliferation; dependent on specific growth factor activity such as fibroblast growth factors and transforming growth factor beta.

FGF2

GO:0014846

BP

esophagus smooth muscle contraction

A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the esophagus. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The esophagus is the muscular membranous segment between the pharynx and the stomach in the upper gastrointestinal tract.

SULF2, SULF1

GO:0014850

BP

response to muscle activity

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a muscle activity stimulus.

MSTN, ITGA2, SRD5A1, CAPN3, ADSL, PRKAA2, POSTN, HIF1A, TNS2, ADSSL1, RYR2, PPARGC1A

GO:0014853

BP

regulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction

Any process, involved in skeletal muscle contraction, that modulates the establishment or extent of the excitatory postsynaptic potential (EPSP). Excitatory postsynaptic potential (EPSP) is a temporay increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential.

DMPK

GO:0014854

BP

response to inactivity

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an inactivity stimulus.

DRD2, IL10

GO:0014858

BP

positive regulation of skeletal muscle cell proliferation

Any process that activates or increases the frequency, rate or extent of skeletal muscle cell proliferation.

SEPN1

GO:0014866

BP

skeletal myofibril assembly

The process whose specific outcome is the progression of the skeletal myofibril over time, from its formation to the mature structure. A skeletal myofibril is a myofibril specific to skeletal muscle cells.

CFLAR

GO:0014873

BP

response to muscle activity involved in regulation of muscle adaptation

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a muscle activity stimulus. This process occurs as part of the regulation of muscle adaptation.

AGT, SEPN1

GO:0014876

BP

response to injury involved in regulation of muscle adaptation

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a injury. This process occurs as part of the regulation of muscle adaptation.

NOL3

GO:0014878

BP

response to electrical stimulus involved in regulation of muscle adaptation

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electrical stimulus. This process occurs as part of the regulation of muscle adaptation.

PPARGC1A

GO:0014883

BP

transition between fast and slow fiber

The process of conversion of fast-contracting muscle fibers to a slower character. This may involve slowing of contractile rate, slow myosin gene induction, increase in oxidative metabolic properties, altered electrophysiology and altered innervation. This process also regulates skeletal muscle adapatation.

TNNT1, ATP2A2, PPP3CA

GO:0014886

BP

transition between slow and fast fiber

The process of conversion of slow-contracting muscle fibers to a faster character. This may involve increasing of contractile rate, fast myosin gene induction, increase in glycolytic metabolic properties, altered electrophysiology and altered innervation. This process also regulates skeletal muscle adapatation.

GTF2I

GO:0014894

BP

response to denervation involved in regulation of muscle adaptation

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a denervation stimulus. This process occurs as part of the regulation of muscle adaptation.

HDAC4, FBXO32, MTMR4

GO:0014896

BP

muscle hypertrophy

The muscle system process that results in enlargement or overgrowth of all or part of a muscle organ due to an increase in the size of its muscle cells. Physiological hypertrophy is a normal process during development (it stops in cardiac muscle after adolescence) and can also be brought on in response to demand. In athletes cardiac and skeletal muscles undergo hypertrophy stimulated by increasing muscle activity on exercise. Smooth muscle cells in the uterus undergo hypertrophy during pregnancy.

IGF1

GO:0014898

BP

cardiac muscle hypertrophy in response to stress

The physiological enlargement or overgrowth of all or part of the heart muscle due to an increase in size (not length) of individual cardiac muscle fibers, without cell division, as a result of a disturbance in organismal or cellular homeostasis.

ATP2A2, HDAC4, MEF2C, PPP3CA, EZH2, GATA6, KLF15

GO:0014902

BP

myotube differentiation

The process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotube differentiation starts with myoblast fusion and the appearance of specific cell markers (this is the cell development step). Then individual myotubes can fuse to form bigger myotubes and start to contract. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.

SKI, MEF2C, MYEF2

GO:0014904

BP

myotube cell development

The process aimed at the progression of a myotube cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.

IGF1, NFATC2, SMYD3

GO:0014909

BP

smooth muscle cell migration

The orderly movement of a smooth muscle cell from one site to another, often during the development of a multicellular organism.

PLAU, PLAT, ITGB3, DDR1

GO:0014910

BP

regulation of smooth muscle cell migration

Any process that modulates the frequency, rate or extent of smooth muscle cell migration.

PLAU, PDGFA, ACE, SORL1, PLXNA1

GO:0014911

BP

positive regulation of smooth muscle cell migration

Any process that activates, maintains or increases the frequency, rate or extent of smooth muscle cell migration.

NRP1, PDGFB, VTN, IGF1, PDGFRB, BCL2, CCL5, ITGA2, HDAC4, FOXO4, CAMK2D, POSTN, SEMA6D, HAS2, RETN, NOX4

GO:0014912

BP

negative regulation of smooth muscle cell migration

Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle cell migration.

SLIT2, SERPINE1, IGFBP3, IGFBP5, BMPR1A, PPARD, ILK, ADIPOQ, SEMA6D, TRIB1, PPARGC1A, NDRG4

GO:0014916

BP

regulation of lung blood pressure

The process that modulates the force with which blood travels through the lungs. The process is controlled by a balance of processes that increase pressure and decrease pressure.

BMPR2

GO:0015012

BP

heparan sulfate proteoglycan biosynthetic process

The chemical reactions and pathways resulting in the formation of the heparan sulfate proteoglycan, a glycosaminoglycan with repeat unit consisting of alternating alpha-(1->4)-linked hexuronic acid and glucosamine residues; the former are a mixture of sulfated and nonsulfated D-glucuronic acid and L-iduronic acid; the L-iduronic acid is either sulfated or acetylated on its amino group as well as being sulfated on one of its hydroxyl groups; heparan sulfate chains are covalently linked to peptidyl-serine by a glycosidic attachment through the trisaccharide galactosyl-galactosyl-xylosyl to serine residues.

NDST1, EXT1, EXT2, XYLT2, DSE, HS3ST3B1

GO:0015014

BP

heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process

The chemical reactions and pathways resulting in the formation of polysaccharide chain component of heparan sulfate proteoglycan.

EXT1, CSGALNACT1, EXT2

GO:0015015

BP

heparan sulfate proteoglycan biosynthetic process, enzymatic modification

The modification, often by sulfation, of sugars incorporated into heparan sulfate after polymerization.

HS6ST1, HS6ST2, HS3ST3B1

GO:0015031

BP

protein transport

The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

VPS37C, UNC119B, WASH1, BBIP1, GPR89A, SNAP23, EXOC5, ARHGAP33, COPE, ITGB1BP1, RAB29, NACAD, SCAMP1, SCAMP2, AP5Z1, CHMP2A, ACTN4, KDELR3, SNX3, EXOC3, RAMP1, RAMP3, VPS4B, SEC22B, RP2, SEC31A, SNX4, KIF20A, TNKS, SFT2D2, SNAP29, COL1A1, GPR89B, HSP90B1, XBP1, ARF4, BTF3, RAB3B, RAB5A, GDI1, MYH9, EPS15, NASP, CENPF, PSEN1, GDI2, PPT1, RAB5C, RAB7A, RAB9A, IST1, GABARAPL2, RAB4B, RAB2A, RAB5B, STXBP1, RAB11A, RAP1A, VAMP2, ARF1, ARF5, DAB2, PPID, NUP160, SELENBP1, UNC119, GPM6B, MTM1, COG2, RABEP1, STXBP2, SLC15A2, DUOXA1, DUOXA2, C11orf73, CCDC93, DOPEY1, STXBP5, DENND4C, RAB12, AFTPH, RAB11FIP1, PGAP1, MON2, CCDC91, VPS13B, TMED4, HOOK3, FRAS1, ERC1, ARL17A, BBS7, VPS52, VPS8, COMMD1, SLC15A4, ARFGAP2, ATG16L2, VPS37A, NUP43, NUP37, MCFD2, KIF18A, TTC8, DENND1A, NUP210, IPO4, SCFD2, RAB2B, PDCD6IP, SFT2D1, AHCTF1, GBF1, SCAMP4, YIPF5, SNX21, EXOC4, RHBDF1, RAB39B, HOOK2, SEH1L, MVB12A, C5orf30, SEC22A, SEC16B, EXOC2, ANKRD27, LYST, NDC1, EIF5A2, AP5M1, RAB1B, LMAN2L, ATG10, PHAX, AKTIP, ECT2, PLEKHF2, SEC61A2, LIN7B, GOPC, VTA1, ENY2, PARP11, EIF4ENIF1, RAB6B, LIN7C, EXOC1, SDAD1, BET1L, FMN2, RRBP1, ADAMTS9, DMBT1, RAB21, RAB22A, RAB23, MYO5B, SNX12, NPIPA1, AGAP1, EXOC7, STXBP5L, COG6, SNX24, TMED5, CCDC53, GOLT1B, TMED3, AP4S1, DNAJC15, ARFGEF2

GO:0015074

BP

DNA integration

The process in which a segment of DNA is incorporated into another, usually larger, DNA molecule such as a chromosome.

BANF1

GO:0015670

BP

carbon dioxide transport

The directed movement of carbon dioxide (CO2) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

CA2

GO:0015671

BP

oxygen transport

The directed movement of oxygen (O2) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

MYC, HBB, HBG1, HBA1, CYGB, IPCEF1, NGB

GO:0015672

BP

monovalent inorganic cation transport

The directed movement of inorganic cations with a valency of one into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Inorganic cations are atoms or small molecules with a positive charge which do not contain carbon in covalent linkage.

ASIC2

GO:0015677

BP

copper ion import

The directed movement of copper ions into a cell or organelle.

STEAP4

GO:0015680

BP

intracellular copper ion transport

The directed movement of copper (Cu) ions within a cell.

ATOX1, CCS

GO:0015684

BP

ferrous iron transport

The directed movement of ferrous iron (Fe(II) or Fe2+) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

SLC11A2

GO:0015689

BP

molybdate ion transport

The directed movement of molybdate (MoO4 2-) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Molybdate is the bivalent anion derived from molybdic acid.

MFSD5

GO:0015692

BP

lead ion transport

The directed movement of lead (Pb) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

SLC11A2

GO:0015693

BP

magnesium ion transport

The directed movement of magnesium (Mg) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

NIPA2, CNNM2

GO:0015695

BP

organic cation transport

The directed movement of organic cations into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Organic cations are atoms or small molecules with a positive charge which contain carbon in covalent linkage.

SLC22A1, SLC22A3, SLC22A18, SLC47A1, RHBG, SLC7A8

GO:0015696

BP

ammonium transport

The directed movement of ammonium into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Ammonium is the cation NH4+ which is formed from N2 by root-nodule bacteria in leguminous plants and is an excretory product in ammonotelic animals.

SLC12A2, RHBG

GO:0015697

BP

quaternary ammonium group transport

The directed movement into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore of quaternary ammonium compounds, any compound that can be regarded as derived from ammonium hydroxide or an ammonium salt by replacement of all four hydrogen atoms of the NH4+ ion by organic groups.

SLC22A1, SLC22A3, SLC22A5

GO:0015698

BP

inorganic anion transport

The directed movement of inorganic anions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Inorganic anions are atoms or small molecules with a negative charge which do not contain carbon in covalent linkage.

ASNA1, SLC4A8, SLC4A4

GO:0015701

BP

bicarbonate transport

The directed movement of bicarbonate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

CA12, BEST1, CA2, SLC4A2, CA3, CFTR, CA4, SLC26A2, HBB, HBA1, SLC4A8, SLC26A11, CA13, SLC26A1, SLC4A4

GO:0015705

BP

iodide transport

The directed movement of iodide into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

SLC5A5

GO:0015707

BP

nitrite transport

The directed movement of nitrite into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

SLC11A1