GO ID |
Ontology |
GO Term |
Term Definition |
Proteins |
GO:0006660
|
BP
|
phosphatidylserine catabolic process
|
The chemical reactions and pathways resulting in the breakdown of phosphatidylserines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of L-serine.
|
ABHD12
|
GO:0006661
|
BP
|
phosphatidylinositol biosynthetic process
|
The chemical reactions and pathways resulting in the formation of phosphatidylinositol, any glycophospholipid in which the sn-glycerol 3-phosphate residue is esterified to the 1-hydroxyl group of 1D-myo-inositol.
|
PIK3CD,
PIK3C2A,
PIP5K1B,
SYNJ2,
INPP4B,
SYNJ1,
PIP5K1C,
FGF2,
PLCG2,
PIK3R1,
IMPA1,
PIK3CA,
PIK3CB,
PIK3CG,
PTEN,
PIP4K2B,
ARF1,
OCRL,
MTM1,
MTMR1,
MTMR2,
SLC27A1,
PIK3C3,
INPP5D,
CDS1,
SH3YL1,
INPP4A,
PIK3R4,
INPP5K,
INPP5E,
MTMR4,
PI4KB,
PIKFYVE
|
GO:0006662
|
BP
|
glycerol ether metabolic process
|
The chemical reactions and pathways involving glycerol ethers, any anhydride formed between two organic hydroxy compounds, one of which is glycerol.
|
TXN,
TXN2
|
GO:0006663
|
BP
|
platelet activating factor biosynthetic process
|
The chemical reactions and pathways resulting in the formation of platelet activating factor, 1-O-alkyl-2-acetyl-sn-glycerol 3-phosphocholine, where alkyl = hexadecyl or octadecyl. Platelet activating factor is an inflammatory mediator released from a variety of cells in response to various stimuli.
|
PLA2G5,
PLA2G4A,
LPCAT2
|
GO:0006664
|
BP
|
glycolipid metabolic process
|
The chemical reactions and pathways involving glycolipids, a class of 1,2-di-O-acylglycerols joined at oxygen 3 by a glycosidic linkage to a carbohydrate part (usually a mono-, di- or tri-saccharide). Some substances classified as bacterial glycolipids have the sugar group acylated by one or more fatty acids and the glycerol group may be absent.
|
KDELC1,
KDELC2,
ST6GALNAC4,
ST3GAL6
|
GO:0006665
|
BP
|
sphingolipid metabolic process
|
The chemical reactions and pathways involving sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid).
|
TH,
SERINC3,
SERINC5,
SERINC2,
SERINC1
|
GO:0006670
|
BP
|
sphingosine metabolic process
|
The chemical reactions and pathways involving sphingosine (sphing-4-enine), trans-D-erytho-2-amino-octadec-4-ene-1,3-diol, a long chain amino diol sphingoid base that occurs in most sphingolipids in animal tissues.
|
SGPP2,
SPHK1
|
GO:0006672
|
BP
|
ceramide metabolic process
|
The chemical reactions and pathways involving ceramides, any N-acylated sphingoid.
|
PPP2R1A,
CLN3,
ASAH1,
ORMDL2,
NSMAF
|
GO:0006678
|
BP
|
glucosylceramide metabolic process
|
The chemical reactions and pathways involving glucosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of glucose by a ceramide group. They are neutral glycolipids containing equimolar amounts of fatty acid, glucose, and sphingosine or a sphingosine derivative.
|
CLN3
|
GO:0006679
|
BP
|
glucosylceramide biosynthetic process
|
The chemical reactions and pathways resulting in the formation of glucosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of glucose by a ceramide group.
|
UGCG
|
GO:0006680
|
BP
|
glucosylceramide catabolic process
|
The chemical reactions and pathways resulting in the breakdown of glucosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of glucose by a ceramide group.
|
GBA2
|
GO:0006681
|
BP
|
galactosylceramide metabolic process
|
The chemical reactions and pathways involving galactosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of galactose by a ceramide group.
|
CLN3
|
GO:0006683
|
BP
|
galactosylceramide catabolic process
|
The chemical reactions and pathways resulting in the breakdown of galactosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of galactose by a ceramide group.
|
GALC
|
GO:0006684
|
BP
|
sphingomyelin metabolic process
|
The chemical reactions and pathways involving sphingomyelin, N-acyl-4-sphingenyl-1-O-phosphorylcholine, any of a class of phospholipids in which the amino group of sphingosine is in amide linkage with one of several fatty acids, while the terminal hydroxyl group of sphingosine is esterified to phosphorylcholine.
|
CLN3
|
GO:0006685
|
BP
|
sphingomyelin catabolic process
|
The chemical reactions and pathways resulting in the breakdown of sphingomyelin, N-acyl-4-sphingenyl-1-O-phosphorylcholine.
|
SMPD4
|
GO:0006686
|
BP
|
sphingomyelin biosynthetic process
|
The chemical reactions and pathways resulting in the formation of sphingomyelin, N-acyl-4-sphingenyl-1-O-phosphorylcholine.
|
SPTLC2,
SGMS1,
SGMS2
|
GO:0006687
|
BP
|
glycosphingolipid metabolic process
|
The chemical reactions and pathways involving glycosphingolipids, any compound with residues of sphingoid and at least one monosaccharide.
|
HEXA,
PSAP,
STS,
KIT,
ARSA,
ARSB,
GM2A,
ARSD,
GALC,
CREM,
BAX,
ASAH1,
UGCG,
ARSK,
SUMF1,
NEU1,
GBA2,
SMPD4,
GLTP
|
GO:0006688
|
BP
|
glycosphingolipid biosynthetic process
|
The chemical reactions and pathways resulting in the formation of glycosphingolipid, a compound with residues of sphingoid and at least one monosaccharide.
|
LARGE,
UGCG,
ST6GALNAC5
|
GO:0006689
|
BP
|
ganglioside catabolic process
|
The chemical reactions and pathways resulting in the breakdown of ganglioside, a ceramide oligosaccharide carrying, in addition to other sugar residues, one or more sialic residues.
|
GM2A,
NEU1
|
GO:0006690
|
BP
|
icosanoid metabolic process
|
The chemical reactions and pathways involving icosanoids, any of a group of C20 polyunsaturated fatty acids.
|
PLA2G4A,
PTGIS
|
GO:0006691
|
BP
|
leukotriene metabolic process
|
The chemical reactions and pathways involving leukotriene, a pharmacologically active substance derived from a polyunsaturated fatty acid, such as arachidonic acid.
|
TLR2,
ALOX5,
ALOX15,
ABCC1,
MAPKAPK2,
PTGR1
|
GO:0006693
|
BP
|
prostaglandin metabolic process
|
The chemical reactions and pathways involving prostaglandins, any of a group of biologically active metabolites which contain a cyclopentane ring due to the formation of a bond between two carbons of a fatty acid. They have a wide range of biological activities.
|
PTGES,
HPGD,
PTGS2,
AKR1C3,
AKR1C2,
PTGR1,
ACOX1,
PDPN
|
GO:0006694
|
BP
|
steroid biosynthetic process
|
The chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus; includes de novo formation and steroid interconversion by modification.
|
CYP17A1,
CYP21A2,
CYP19A1,
HSD3B1,
HSD17B1,
PRLR,
SRD5A1,
HSD3B2,
TSPO,
SRD5A2,
HSD17B2,
FDFT1,
PBX1,
LSS,
STAR,
NR0B1,
CYP51A1,
HSD17B12,
HSD17B11,
HINT2,
ACBD3
|
GO:0006695
|
BP
|
cholesterol biosynthetic process
|
The chemical reactions and pathways resulting in the formation of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.
|
INSIG1,
TM7SF2,
CYB5R3,
APOA1,
HMGCR,
G6PD,
CFTR,
FDPS,
FDFT1,
LSS,
MVD,
PRKAA2,
HSD17B7,
HMGCS1,
MVK,
IDI1,
SQLE,
EBP,
DHCR24,
NSDHL,
MSMO1,
CYP51A1,
APOA5,
IDI2,
DHCR7
|
GO:0006696
|
BP
|
ergosterol biosynthetic process
|
The chemical reactions and pathways resulting in the formation of ergosterol, (22E)-ergosta-5,7,22-trien-3-beta-ol, a sterol found in ergot, yeast and moulds.
|
FDFT1,
C14orf1
|
GO:0006699
|
BP
|
bile acid biosynthetic process
|
The chemical reactions and pathways resulting in the formation of bile acids, any of a group of steroid carboxylic acids occurring in bile.
|
ACOT8,
SLC27A2,
CH25H,
SCP2,
STAR,
HSD17B4,
ACOX2,
HSD3B7,
CYP8B1
|
GO:0006700
|
BP
|
C21-steroid hormone biosynthetic process
|
The chemical reactions and pathways resulting in the formation of C21-steroid hormones, steroid compounds containing 21 carbons which function as hormones.
|
CYP11A1,
FDX1,
AKR1B1,
CYP11B1,
CYP11B2,
STAR,
FDX1L
|
GO:0006701
|
BP
|
progesterone biosynthetic process
|
The chemical reactions and pathways resulting in the formation of progesterone, a steroid hormone produced in the ovary which prepares and maintains the uterus for pregnancy. Also found in plants.
|
FSHB,
LHB,
ADM,
STARD3
|
GO:0006702
|
BP
|
androgen biosynthetic process
|
The chemical reactions and pathways resulting in the formation of androgens, C19 steroid hormones that can stimulate the development of male sexual characteristics.
|
HSD17B6,
CYP17A1,
HSD3B1,
SRD5A1,
HSD3B2,
SRD5A2,
SCARB1
|
GO:0006703
|
BP
|
estrogen biosynthetic process
|
The chemical reactions and pathways resulting in the formation of estrogens, C18 steroid hormones that can stimulate the development of female sexual characteristics. Also found in plants.
|
CYP19A1,
HSD3B1,
HSD17B1,
STAR,
HSD17B7,
HSD17B12,
HSD17B11
|
GO:0006704
|
BP
|
glucocorticoid biosynthetic process
|
The chemical reactions and pathways resulting in the formation of glucocorticoids, hormonal C21 corticosteroids synthesized from cholesterol.
|
CYP17A1,
CYP11A1,
CYP21A2,
HSD3B1,
CYP11B1,
HSD3B2,
HSD11B1,
HSD11B2
|
GO:0006705
|
BP
|
mineralocorticoid biosynthetic process
|
The chemical reactions and pathways resulting in the formation of mineralocorticoids, hormonal C21 corticosteroids synthesized from cholesterol.
|
CYP21A2,
HSD3B1,
CYP11B2,
HSD3B2
|
GO:0006706
|
BP
|
steroid catabolic process
|
The chemical reactions and pathways resulting in the breakdown of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus.
|
CYP3A4,
STS,
SRD5A2
|
GO:0006707
|
BP
|
cholesterol catabolic process
|
The chemical reactions and pathways resulting in the breakdown of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.
|
APOE,
MT3,
SCARF1,
SCARB1
|
GO:0006710
|
BP
|
androgen catabolic process
|
The chemical reactions and pathways resulting in the breakdown of androgens, C19 steroid hormones that can stimulate the development of male sexual characteristics.
|
HSD17B6,
HSD17B11
|
GO:0006711
|
BP
|
estrogen catabolic process
|
The chemical reactions and pathways resulting in the breakdown of estrogens, C18 steroid hormones that can stimulate the development of female sexual characteristics. Also found in plants.
|
UGT2B4
|
GO:0006713
|
BP
|
glucocorticoid catabolic process
|
The chemical reactions and pathways resulting in the breakdown of glucocorticoids, hormonal C21 corticosteroids synthesized from cholesterol.
|
YWHAH
|
GO:0006725
|
BP
|
cellular aromatic compound metabolic process
|
The chemical reactions and pathways involving aromatic compounds, any organic compound characterized by one or more planar rings, each of which contains conjugated double bonds and delocalized pi electrons, as carried out by individual cells.
|
SQLE,
CYP1B1
|
GO:0006726
|
BP
|
eye pigment biosynthetic process
|
The chemical reactions and pathways resulting in the formation of eye pigments, any general or particular coloring matter in living organisms, found or utilized in the eye.
|
AP3D1,
TYR
|
GO:0006729
|
BP
|
tetrahydrobiopterin biosynthetic process
|
The chemical reactions and pathways resulting in the formation of tetrahydrobiopterin, the reduced form of biopterin (2-amino-4-hydroxy-6-(1,2-dihydroxypropyl)-pteridine). It functions as a hydroxylation coenzyme, e.g. in the conversion of phenylalanine to tyrosine.
|
DHFR,
QDPR
|
GO:0006730
|
BP
|
one-carbon metabolic process
|
The chemical reactions and pathways involving the transfer of one-carbon units in various oxidation states.
|
CA12,
AHCYL1,
ALDH1L1,
DHFR,
CA2,
CA3,
MTHFD1,
MTHFD2,
CA4,
AHCY,
MAT2A,
CA8,
ALDH1L2,
MTHFD1L,
CA13,
MTHFD2L,
MAT2B
|
GO:0006734
|
BP
|
NADH metabolic process
|
The chemical reactions and pathways involving reduced nicotinamide adenine dinucleotide (NADH), a coenzyme present in most living cells and derived from the B vitamin nicotinic acid.
|
IDH3B,
MDH1,
MDH2,
VCP,
OGDH,
MDH1B
|
GO:0006738
|
BP
|
nicotinamide riboside catabolic process
|
The chemical reactions and pathways resulting in the breakdown of nicotinamide riboside, the product of the formation of a glycosidic bond between ribose and nicotinamide.
|
PNP
|
GO:0006739
|
BP
|
NADP metabolic process
|
The chemical reactions and pathways involving nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions; metabolism may be of either the oxidized form, NADP, or the reduced form, NADPH.
|
G6PD,
DCXR,
FMO2
|
GO:0006740
|
BP
|
NADPH regeneration
|
A metabolic process that generates a pool of NADPH by the reduction of NADP+.
|
IDH1,
G6PD
|
GO:0006741
|
BP
|
NADP biosynthetic process
|
The chemical reactions and pathways resulting in the formation of nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions; biosynthesis may be of either the oxidized form, NADP, or the reduced form, NADPH.
|
NADK2
|
GO:0006743
|
BP
|
ubiquinone metabolic process
|
The chemical reactions and pathways involving ubiquinone, a lipid-soluble electron-transporting coenzyme.
|
HMGCR
|
GO:0006744
|
BP
|
ubiquinone biosynthetic process
|
The chemical reactions and pathways resulting in the formation of ubiquinone, a lipid-soluble electron-transporting coenzyme.
|
PDSS1,
PDSS2,
COQ2,
COQ3,
COQ4
|
GO:0006749
|
BP
|
glutathione metabolic process
|
The chemical reactions and pathways involving glutathione, the tripeptide glutamylcysteinylglycine, which acts as a coenzyme for some enzymes and as an antioxidant in the protection of sulfhydryl groups in enzymes and other proteins; it has a specific role in the reduction of hydrogen peroxide (H2O2) and oxidized ascorbate, and it participates in the gamma-glutamyl cycle.
|
OPLAH,
GSTA4,
EEF1E1,
GSTZ1,
IDH1,
ETHE1,
GSR,
GPX1,
GSTA1,
GSTP1,
GSTM1,
GSTT2,
MGST1,
G6PD,
GSTM3,
GSTM2,
GSTT1,
GSTO1,
GSTM4,
GLO1,
GSTO2,
GLRX2,
GGT7,
GSTK1
|
GO:0006750
|
BP
|
glutathione biosynthetic process
|
The chemical reactions and pathways resulting in the formation of glutathione, the tripeptide glutamylcysteinylglycine, which acts as a coenzyme for some enzymes and as an antioxidant in the protection of sulfhydryl groups in enzymes and other proteins.
|
OPLAH,
GCLC,
GCLM,
HAGH,
CHAC2,
MGST2,
CHAC1,
GGT7
|
GO:0006751
|
BP
|
glutathione catabolic process
|
The chemical reactions and pathways resulting in the breakdown of glutathione, the tripeptide glutamylcysteinylglycine, which acts as a coenzyme for some enzymes and as an antioxidant in the protection of sulfhydryl groups in enzymes and other proteins.
|
CHAC2,
CHAC1
|
GO:0006754
|
BP
|
ATP biosynthetic process
|
The chemical reactions and pathways resulting in the formation of ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
|
ATP5H,
ATP5L,
TGFB1,
ALDOA,
ATP5J,
ATP5D,
ATP5C1,
ATP5O,
ATP5G3,
ATP5E,
ATP5I,
ATP5G2,
UQCC3,
CHCHD10,
SLC25A13
|
GO:0006760
|
BP
|
folic acid-containing compound metabolic process
|
The chemical reactions and pathways involving a folic acid-containing compound, i.e. any of a group of heterocyclic compounds based on the pteroic acid skeleton conjugated with one or more L-glutamic acid or L-glutamate units.
|
MTHFD1L
|
GO:0006766
|
BP
|
vitamin metabolic process
|
The chemical reactions and pathways involving vitamins. Vitamin is a general term for a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body. Vitamins may be water-soluble or fat-soluble and usually serve as components of coenzyme systems.
|
CYP27B1,
CYP26A1,
CYP2R1,
CYP26B1
|
GO:0006768
|
BP
|
biotin metabolic process
|
The chemical reactions and pathways involving biotin, cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid; the (+) enantiomer is very widely distributed in cells and serves as a carrier in a number of enzymatic beta-carboxylation reactions.
|
ACACB,
VNN1,
PCCA,
PC,
PDZD11,
MCCC1,
MCCC2,
VNN3
|
GO:0006769
|
BP
|
nicotinamide metabolic process
|
The chemical reactions and pathways involving nicotinamide, pyridine-3-carboxamide, the amide of nicotinic acid. It is a member of the B complex of vitamins and occurs widely in living organisms.
|
PTGS2,
NAMPT,
PTGIS,
CARKD
|
GO:0006771
|
BP
|
riboflavin metabolic process
|
The chemical reactions and pathways involving riboflavin (vitamin B2), the precursor for the coenzymes flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD).
|
ENPP1,
RFK,
SLC52A3
|
GO:0006772
|
BP
|
thiamine metabolic process
|
The chemical reactions and pathways involving thiamine (vitamin B1), a water soluble vitamin present in fresh vegetables and meats, especially liver.
|
ACPP,
TPK1
|
GO:0006776
|
BP
|
vitamin A metabolic process
|
The chemical reactions and pathways involving any of the vitamin A compounds, retinol, retinal (retinaldehyde) and retinoic acid, all of which are derivatives of beta-carotene.
|
ALDH1A2,
RBP1,
PPARD
|
GO:0006777
|
BP
|
Mo-molybdopterin cofactor biosynthetic process
|
The chemical reactions and pathways resulting in the formation of the Mo-molybdopterin cofactor, essential for the catalytic activity of some enzymes. The cofactor consists of a mononuclear molybdenum (Mo) ion coordinated by one or two molybdopterin ligands.
|
MOCOS,
GPHN
|
GO:0006778
|
BP
|
porphyrin-containing compound metabolic process
|
The chemical reactions and pathways involving any member of a large group of derivatives or analogs of porphyrin. Porphyrins consists of a ring of four pyrrole nuclei linked each to the next at their alpha positions through a methine group.
|
CYP1A1
|
GO:0006779
|
BP
|
porphyrin-containing compound biosynthetic process
|
The chemical reactions and pathways resulting in the formation of any member of a large group of derivatives or analogs of porphyrin. Porphyrin consists of a ring of four pyrrole nuclei linked each to the next at their alpha positions through a methine group.
|
ABCB6
|
GO:0006781
|
BP
|
succinyl-CoA pathway
|
The chemical reactions that utilize succinyl-CoA in the synthesis of protoporphyrin IX.
|
SUCLA2
|
GO:0006782
|
BP
|
protoporphyrinogen IX biosynthetic process
|
The chemical reactions and pathways resulting in the formation of protoporphyrinogen IX.
|
UROD,
ALAD,
CPOX
|
GO:0006783
|
BP
|
heme biosynthetic process
|
The chemical reactions and pathways resulting in the formation of heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring, from less complex precursors.
|
UROD,
ALAD,
TSPO,
CPOX,
SLC11A2,
NFE2L1,
FXN,
IBA57,
SLC25A39,
TMEM14C
|
GO:0006788
|
BP
|
heme oxidation
|
The chemical reactions and pathways resulting in the loss of electrons from one or more atoms in heme.
|
HMOX1
|
GO:0006790
|
BP
|
sulfur compound metabolic process
|
The chemical reactions and pathways involving the nonmetallic element sulfur or compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione.
|
PAX8,
CHST3,
CHST4,
ISCA1,
CHST5,
CHST6,
CHST7,
CHST2
|
GO:0006796
|
BP
|
phosphate-containing compound metabolic process
|
The chemical reactions and pathways involving the phosphate group, the anion or salt of any phosphoric acid.
|
ENPP3,
TGFB1,
ACYP1,
ENPP1,
PTPRB,
PTPRD,
IMPA1,
INPP1,
ENPP2,
SLC20A1,
INPP5D
|
GO:0006797
|
BP
|
polyphosphate metabolic process
|
The chemical reactions and pathways involving a polyphosphate, the anion or salt of polyphosphoric acid.
|
MINPP1
|
GO:0006801
|
BP
|
superoxide metabolic process
|
The chemical reactions and pathways involving superoxide, the superoxide anion O2- (superoxide free radical), or any compound containing this species.
|
SH3PXD2B,
CCS,
SOD2,
CYBB,
NCF2,
NOXA1,
NOX4
|
GO:0006805
|
BP
|
xenobiotic metabolic process
|
The chemical reactions and pathways involving a xenobiotic compound, a compound foreign to living organisms. Used of chemical compounds, e.g. a xenobiotic chemical, such as a pesticide.
|
AIP,
MGST3,
GSTA4,
CYP26A1,
AKR7A2,
AOC2,
CYP2E1,
UGT2B4,
EPHX1,
CYP3A4,
GSTP1,
SULT1A3,
MGST1,
CYP2D6,
CYP2C9,
NQO1,
CYP2B6,
CYP3A5,
AADAC,
PTGS1,
CYP3A7,
RORA,
AHR,
AKR1C1,
CYP1B1,
AOC3,
CYP2W1,
FMO2,
MGST2,
GSTO2,
CYP26B1
|
GO:0006807
|
BP
|
nitrogen compound metabolic process
|
The chemical reactions and pathways involving organic or inorganic compounds that contain nitrogen, including (but not limited to) nitrogen fixation, nitrification, denitrification, assimilatory/dissimilatory nitrate reduction and the interconversion of nitrogenous organic matter and ammonium.
|
VNN1,
PKD1,
MYO1E,
VNN3,
SEC63
|
GO:0006808
|
BP
|
regulation of nitrogen utilization
|
Any process that modulates the frequency, rate or extent of nitrogen utilization.
|
BCL2,
BAX
|
GO:0006809
|
BP
|
nitric oxide biosynthetic process
|
The chemical reactions and pathways resulting in the formation of nitric oxide, nitrogen monoxide (NO), a colorless gas only slightly soluble in water.
|
DDAH2,
NQO1,
NOS3,
AKT1,
RORA,
SLC7A2,
CYP1B1
|
GO:0006810
|
BP
|
transport
|
The directed movement of substances (such as macromolecules, small molecules, ions) or cellular components (such as complexes and organelles) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter, pore or motor protein.
|
FABP12,
SLC33A1,
GOLIM4,
ABCC5,
AQP9,
ASNA1,
ENSA,
SLC37A4,
MPDU1,
SEC14L2,
AQP8,
ABCA8,
SLC25A14,
PMP2,
TTR,
ALB,
SLC25A5,
DBI,
GNAI3,
RBP1,
PAEP,
AR,
SLC25A4,
CFTR,
FABP4,
SLC25A16,
GJA1,
ATP2B1,
CNGA1,
SLC6A1,
CHRNA5,
SRI,
SLC6A6,
GABRA5,
ABCC1,
GJC1,
PTGDS,
CRAT,
SLC6A8,
GRIA4,
CLCN3,
CLCN4,
CLCN5,
CLCN7,
CLCNKA,
CLCNKB,
SLC7A2,
CACNB3,
OAZ1,
ATP1B3,
SLC12A2,
UCP2,
SMAD3,
PITPNA,
SLC25A3,
SLC7A5,
SLC20A2,
CDH17,
GRIN2A,
G3BP1,
TCOF1,
LAPTM5,
ITPR2,
CLCA4,
PEA15,
RALBP1,
CACNA1E,
SLC15A2,
LDLRAP1,
ACBD5,
SYPL2,
CHIC1,
SLC27A4,
SLC51A,
LAPTM4B,
CREBRF,
SLC35F2,
TRPV1,
SLC20A1,
AQP3,
SLC7A6,
SLC9A6,
SLC5A5,
P2RX4,
FEZ1,
TM9SF2,
TTPAL,
SLC25A39,
ACBD3,
ABCB6,
ABCB10,
STAU2,
CLIC5,
TMEM9,
ABCF2,
ASIC3,
SLC7A8,
SLC25A13,
SLC7A7,
SLC6A14,
TCAF1,
MYO5A,
TRPV2,
LYVE1,
SLC4A4
|
GO:0006811
|
BP
|
ion transport
|
The directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
GPR89A,
TMEM63A,
TOMM40,
CYBB,
GPR89B,
CHRNA7,
SLC1A3,
SLC1A2,
GLRB,
SLC1A6,
SLC26A2,
SLC12A2,
LCN2,
SLC20A2,
SLC15A2,
FXN,
SLC25A26,
SLC36A1,
TMC6,
SLC15A4,
SLC20A1,
SLC9A6,
SLC5A5,
PANX2,
SLC26A1,
WNK1,
SLC24A3,
SLC25A10,
SLC9A2,
ATP11B
|
GO:0006812
|
BP
|
cation transport
|
The directed movement of cations, atoms or small molecules with a net positive charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
CHRNB1,
ANO6,
PIEZO1,
PANX1,
TRPC6
|
GO:0006813
|
BP
|
potassium ion transport
|
The directed movement of potassium ions (K+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
KCNK1,
KCNK3,
VPS4B,
CDK2,
GJA5,
NSF,
CDKN1B,
ATP1A2,
SLC12A2,
KCNA1,
KCNMA1,
KCNJ12,
KCNK17,
CHP1,
SLC24A3,
KCNIP2,
KCNG1,
KCNK6
|
GO:0006814
|
BP
|
sodium ion transport
|
The directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
SLC22A5,
TRAPPC10,
ATP1A2,
SCNN1G,
SLC12A2,
SLC10A7,
SCN9A,
SLC4A8,
MFSD4B,
SLC5A11,
NEDD4L,
SLC38A1,
SLC38A10,
SLC4A4
|
GO:0006816
|
BP
|
calcium ion transport
|
The directed movement of calcium (Ca) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
CYP27B1,
RAMP1,
RAMP3,
PRKCB,
FYN,
ANXA6,
SLC3A2,
CCL3,
VDR,
CCL5,
TPT1,
PLN,
SRI,
CORO1A,
CHRNA7,
TRPC1,
PSEN2,
CACNB3,
CACNA2D1,
CCL8,
ATP2C1,
CAV1,
PPP3CA,
TRPC3,
CAMK2D,
PKD2,
ITPR1,
RYR3,
CACHD1,
BSPRY,
CACNG8,
RYR2,
PANX1,
CACNG6,
TRPV6,
TRPV4
|
GO:0006817
|
BP
|
phosphate ion transport
|
The directed movement of phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
IP6K2
|
GO:0006820
|
BP
|
anion transport
|
The directed movement of anions, atoms or small molecules with a net negative charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
SLC4A2,
TSPO,
VDAC2,
LRRC8A,
VDAC3
|
GO:0006821
|
BP
|
chloride transport
|
The directed movement of chloride into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
FXYD1,
CLIC1,
BEST1,
CLIC3,
TSPO,
CLCN4,
CLCN6,
ANO6,
SLC26A1,
TTYH1,
CLIC5
|
GO:0006824
|
BP
|
cobalt ion transport
|
The directed movement of cobalt (Co) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
SLC11A2
|
GO:0006825
|
BP
|
copper ion transport
|
The directed movement of copper (Cu) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
ATOX1,
SLC31A1,
SLC31A2,
SLC11A2,
FKBP4,
COX17,
HEPH
|
GO:0006826
|
BP
|
iron ion transport
|
The directed movement of iron (Fe) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
FTL,
FTH1,
SLC11A1,
NECTIN1,
HEPH,
TTYH1,
SFXN1,
TFR2
|
GO:0006828
|
BP
|
manganese ion transport
|
The directed movement of manganese (Mn) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
ZP3,
TRPC1,
SLC11A1,
SLC11A2,
TRPC3,
TRPC6
|
GO:0006829
|
BP
|
zinc II ion transport
|
The directed movement of zinc (Zn II) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
MT3,
SLC30A9,
SLC30A8,
SLC39A8,
SLC30A1
|
GO:0006833
|
BP
|
water transport
|
The directed movement of water (H2O) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
AQP9,
AQP8,
MIP,
AQP2,
SLC14A1,
AQP3
|
GO:0006835
|
BP
|
dicarboxylic acid transport
|
The directed movement of dicarboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
SLC25A10
|
GO:0006836
|
BP
|
neurotransmitter transport
|
The directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Neurotransmitters are any chemical substance that is capable of transmitting (or inhibiting the transmission of) a nerve impulse from a neuron to another cell.
|
SLC22A1,
SYNJ1,
SLC6A1,
SLC6A6,
SLC6A8,
ICA1,
SLC6A14
|
GO:0006837
|
BP
|
serotonin transport
|
The directed movement of serotonin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Serotonin (5-hydroxytryptamine) is a monoamine neurotransmitter occurring in the peripheral and central nervous systems.
|
SLC18A2
|
GO:0006839
|
BP
|
mitochondrial transport
|
Transport of substances into, out of or within a mitochondrion.
|
SLC25A14,
HSP90AA1,
UCP1,
PSEN1,
UCP2,
UCP3,
STARD3,
SLC25A30,
SLC25A10
|
GO:0006851
|
BP
|
mitochondrial calcium ion transport
|
The directed movement of calcium ions (Ca2+) into, out of or within a mitochondrion.
|
MICU2,
MCUR1,
SLC25A23
|
GO:0006853
|
BP
|
carnitine shuttle
|
The transfer of acyl groups to and from acyl-CoA molecules to form O-acylcarnitine, which can exchange across the mitochondrial inner membrane with unacylated carnitine.
|
ACACB,
CPT1A,
PRKAA2,
CPT1B
|
GO:0006855
|
BP
|
drug transmembrane transport
|
The process in which a drug is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
|
SLC22A1,
SLC31A1,
ATP8B1,
SLC22A3,
SLC22A5,
ABCA8,
EBP,
SLC22A18,
SLC47A1,
TMEM30A
|
GO:0006857
|
BP
|
oligopeptide transport
|
The directed movement of oligopeptides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Oligopeptides are molecules that contain a small number (2 to 20) of amino-acid residues connected by peptide linkages.
|
CDH17,
SLC15A2,
SLC15A4
|
GO:0006860
|
BP
|
extracellular amino acid transport
|
The directed extracellular movement of amino acids.
|
SLC1A5
|
GO:0006863
|
BP
|
purine nucleobase transport
|
The directed movement of purine bases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
AQP9
|
GO:0006864
|
BP
|
pyrimidine nucleotide transport
|
The directed movement of a pyrimidine nucleotide, any compound consisting of a pyrimidine nucleoside esterified with (ortho)phosphate, into, out of or within a cell.
|
SLC25A36
|