GO:0003845

MF

11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity

Catalysis of the reaction: an 11-beta-hydroxysteroid + NAD(P)+ = an 11-oxosteroid + NAD(P)H + H(+).

HSD11B1, HSD11B2

GO:0003846

MF

2-acylglycerol O-acyltransferase activity

Catalysis of the reaction: acyl-CoA + 2-acylglycerol = CoA + diacylglycerol.

DGAT2

GO:0003847

MF

1-alkyl-2-acetylglycerophosphocholine esterase activity

Catalysis of the reaction: 2-acetyl-1-alkyl-sn-glycero-3-phosphocholine + H2O = 1-alkyl-sn-glycero-3-phosphocholine + acetate.

PAFAH1B2, PLA2G7, PAFAH1B3

GO:0003854

MF

3-beta-hydroxy-delta5-steroid dehydrogenase activity

Catalysis of the reaction: a 3-beta-hydroxy-delta(5)-steroid + NAD+ = a 3-oxo-delta(5)-steroid + NADH + H(+).

HSD3B1, HSD3B2, NSDHL, HSD3B7

GO:0003857

MF

3-hydroxyacyl-CoA dehydrogenase activity

Catalysis of the reaction: (S)-3-hydroxyacyl-CoA + NAD+ = 3-oxoacyl-CoA + NADH + H(+).

HSD17B4, HADHB, HADH, HSD17B10, CRYL1

GO:0003858

MF

3-hydroxybutyrate dehydrogenase activity

Catalysis of the reaction: (R)-3-hydroxybutanoate + NAD(+) = acetoacetate + H(+) + NADH.

BDH2

GO:0003860

MF

3-hydroxyisobutyryl-CoA hydrolase activity

Catalysis of the reaction: 3-hydroxy-2-methylpropanoyl-CoA + H2O = CoA + 3-hydroxy-2-methylpropanoate.

HIBCH

GO:0003863

MF

3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity

Catalysis of the reaction: 3-methyl-2-oxobutanoate + lipoamide = S-(2-methylpropanoyl)dihydrolipoamide + CO2.

BCKDHA, BCKDHB

GO:0003865

MF

3-oxo-5-alpha-steroid 4-dehydrogenase activity

Catalysis of the reaction: a 3-oxo-5-alpha-steroid + acceptor = a 3-oxo-delta(4)-steroid + reduced acceptor.

SRD5A1, SRD5A2

GO:0003867

MF

4-aminobutyrate transaminase activity

Catalysis of the reaction: 4-aminobutanoate + amino group acceptor = succinate semialdehyde + amino acid.

ABAT

GO:0003868

MF

4-hydroxyphenylpyruvate dioxygenase activity

Catalysis of the reaction: 4-hydroxyphenylpyruvate + O2 = homogentisate + CO2.

HPDL

GO:0003872

MF

6-phosphofructokinase activity

Catalysis of the reaction: ATP + D-fructose-6-phosphate = ADP + D-fructose 1,6-bisphosphate.

PFKL

GO:0003873

MF

6-phosphofructo-2-kinase activity

Catalysis of the reaction: beta-D-fructose 6-phosphate + ATP = beta-D-fructose 2,6-bisphosphate + ADP + 2 H(+).

PFKFB2, PFKFB1, PFKFB3, PFKFB4

GO:0003875

MF

ADP-ribosylarginine hydrolase activity

Catalysis of the reaction: N2-(ADP-D-ribosyl)-L-arginine + H2O = L-arginine + ADP-ribose.

ADPRH

GO:0003876

MF

AMP deaminase activity

Catalysis of the reaction: AMP + H2O = IMP + NH3.

AMPD3

GO:0003880

MF

protein C-terminal carboxyl O-methyltransferase activity

Catalysis of the transfer of a methyl group to the oxygen atom of a carboxyl group at the C-terminal of a protein.

ICMT, LCMT1

GO:0003883

MF

CTP synthase activity

Catalysis of the reaction: ATP + UTP + NH3 = ADP + phosphate + CTP.

CTPS1, CTPS2

GO:0003886

MF

DNA (cytosine-5-)-methyltransferase activity

Catalysis of the reaction: S-adenosyl-L-methionine + DNA containing cytosine = S-adenosyl-L-homocysteine + DNA containing 5-methylcytosine.

DNMT1, DNMT3B

GO:0003887

MF

DNA-directed DNA polymerase activity

Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1); the synthesis of DNA from deoxyribonucleotide triphosphates in the presence of a DNA template and a 3'hydroxyl group.

REV3L, POLQ, POLA1, POLD1, POLG, POLE2, POLE, POLA2, POLD3, PAPD5, PRIMPOL, MYBBP1A, POLD4, POLE4, POLE3, CHRAC1, POLK, POLI, POLH

GO:0003896

MF

DNA primase activity

Catalysis of the synthesis of a short RNA primer on a DNA template, providing a free 3'-OH that can be extended by DNA-directed DNA polymerases.

POLA1, PRIM1, PRIM2, PRIMPOL

GO:0003899

MF

DNA-directed RNA polymerase activity

Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template, i.e. the catalysis of DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.

POLR1C, POLR3G, CD3EAP, POLR2D, CRCP, POLR2E, POLR2A, POLR2I, POLR2J, POLR2G, POLR2L, MED21, POLR3C, POLR2J2, POLR3F, MED20, POLR3K

GO:0003905

MF

alkylbase DNA N-glycosylase activity

Catalysis of the reaction: DNA with alkylated base + H2O = DNA with abasic site + alkylated base. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar to remove an alkylated base, leaving an apyrimidinic or apurinic site.

MPG

GO:0003906

MF

DNA-(apurinic or apyrimidinic site) lyase activity

Catalysis of the cleavage of the C-O-P bond 3' to the apurinic or apyrimidinic site in DNA by a beta-elimination reaction, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

HMGA2, NTHL1, ALKBH1, NEIL3

GO:0003909

MF

DNA ligase activity

Catalysis of the formation of a phosphodiester bond between the 3'-hydroxyl group at the end of one DNA chain and the 5'-phosphate group at the end of another. This reaction requires an energy source such as ATP or NAD+.

LIG1

GO:0003910

MF

DNA ligase (ATP) activity

Catalysis of the reaction: ATP + deoxyribonucleotide(n) + deoxyribonucleotide(m) = AMP + diphosphate + deoxyribonucleotide(n+m).

PARP1, LIG1, PARP2

GO:0003917

MF

DNA topoisomerase type I activity

Catalysis of a DNA topological transformation by transiently cleaving one DNA strand at a time to allow passage of another strand; changes the linking number by +1 per catalytic cycle.

TOP1

GO:0003918

MF

DNA topoisomerase type II (ATP-hydrolyzing) activity

Catalysis of a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined; product release is coupled to ATP binding and hydrolysis; changes the linking number in multiples of 2.

TOP2A

GO:0003920

MF

GMP reductase activity

Catalysis of the reaction: IMP + NADP(+) + NH(4)(+) = GMP + 2 H(+) + NADPH.

GMPR

GO:0003921

MF

GMP synthase activity

Catalysis of the reaction: ATP + xanthosine 5'-phosphate + NH3 = AMP + diphosphate + GMP.

GMPS

GO:0003922

MF

GMP synthase (glutamine-hydrolyzing) activity

Catalysis of the reaction: ATP + xanthosine 5'-phosphate + L-glutamine + H2O = AMP + diphosphate + GMP + L-glutamate.

GMPS

GO:0003923

MF

GPI-anchor transamidase activity

Catalysis of the formation of the linkage between a protein and a glycosylphosphatidylinositol anchor. The reaction probably occurs by subjecting a peptide bond to nucleophilic attack by the amino group of ethanolamine-GPI, transferring the protein from a signal peptide to the GPI anchor.

PIGK, PIGT, PIGU

GO:0003924

MF

GTPase activity

Catalysis of the reaction: GTP + H2O = GDP + phosphate.

GTPBP10, RAB27B, RHOD, DDX3X, RAB29, OPA1, EIF5B, MFN2, DIRAS3, KRAS, TUBB4A, GNAI2, TUBB, GNAI3, RAP2A, RRAS, RALA, RALB, EEF2, RAC2, GSPT1, GNB3, RHOQ, ARF4, RAB3B, RAB5A, TUBG1, GNA11, GBP1, GBP2, TRIM23, NUDT1, GNL1, EIF2S3, ARL4D, GNAQ, RAB5C, RAB7A, RAB9A, RAB28, RAB27A, ARHGDIB, EIF5, GEM, RRAD, RAC3, CDC42, SRP54, RAB2A, RAB5B, RHOA, GNG11, RRAS2, RAB11A, RHOB, RAB1A, RAP1A, GNB1, GNB2, RAC1, GNAI1, GNG5, EEF1A1, TUBA1B, TUBA4A, TUBB4B, ARF1, ARF5, GNAS, GNA12, EEF1A2, ARHGAP5, TUBB3, RAB31, RAB32, TUBA3C, TUBB2A, RAB33A, RHEB, RAB11B, TSR1, GNAS, ATL3, GBP6, TUBA1A, RHOU, MMAA, ADSSL1, GTPBP8, GUF1, ATL2, RAB8B, RIT1, GTPBP3, RERG, ARL8A, RASD2, GFM1, MTG1, TUBB6, TUBB2B, GNL3, GBP3, TUBB1, RHOJ, MTG2, RRAGC, RRAGD, RAB6B, ARL8B, GNL3L, NKIRAS1, DNAJC27, TUBE1, TUBD1, RAB21, RAB22A, RAB23, RASD1, HBS1L, SAR1B

GO:0003939

MF

L-iditol 2-dehydrogenase activity

Catalysis of the reaction: L-iditol + NAD+ = L-sorbose + NADH + H+.

SORD

GO:0003943

MF

N-acetylgalactosamine-4-sulfatase activity

Catalysis of the hydrolysis of the 4-sulfate groups of the N-acetyl-D-galactosamine 4-sulfate units of chondroitin sulfate and dermatan sulfate.

ARSB, GALNS

GO:0003944

MF

N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase activity

Catalysis of the reaction: glycoprotein N-acetyl-D-glucosaminyl-phospho-D-mannose + H2O = N-acetyl-D-glucosamine + glycoprotein phospho-D-mannose.

NAGPA

GO:0003945

MF

N-acetyllactosamine synthase activity

Catalysis of the reaction: UDP-galactose + N-acetyl-D-glucosamine = UDP + N-acetyllactosamine.

B4GALT4, B4GALT1

GO:0003950

MF

NAD+ ADP-ribosyltransferase activity

Catalysis of the reaction: NAD+ + (ADP-D-ribosyl)(n)-acceptor = nicotinamide + (ADP-D-ribosyl)(n+1)-acceptor.

TNKS, PARP1, PARP6, PARP8, TNKS2, PARP11, PARP2

GO:0003951

MF

NAD+ kinase activity

Catalysis of the reaction: ATP + NAD(+) = ADP + 2 H(+) + NADP(+).

NADK2

GO:0003952

MF

NAD+ synthase (glutamine-hydrolyzing) activity

Catalysis of the reaction: ATP + deamido-NAD+ + L-glutamine + H2O = AMP + diphosphate + NAD+ + L-glutamate.

NADSYN1

GO:0003954

MF

NADH dehydrogenase activity

Catalysis of the reaction: NADH + H+ + acceptor = NAD+ + reduced acceptor.

NDUFS8, NDUFS2, NDUFA13

GO:0003955

MF

NAD(P)H dehydrogenase (quinone) activity

Catalysis of the reaction: NAD(P)H + H+ + a quinone = NAD(P)+ + a hydroquinone.

NQO1

GO:0003960

MF

NADPH:quinone reductase activity

Catalysis of the reaction: NADPH + H+ + quinone = NADP+ + semiquinone.

CRYZL1, CRYZ

GO:0003962

MF

cystathionine gamma-synthase activity

Catalysis of the reaction: O-succinyl-L-homoserine + L-cysteine = cystathionine + succinate.

CTH

GO:0003963

MF

RNA-3'-phosphate cyclase activity

Catalysis of the reaction: ATP + RNA 3'-terminal-phosphate = AMP + diphosphate + RNA terminal-2',3'-cyclic-phosphate.

RTCA

GO:0003968

MF

RNA-directed RNA polymerase activity

Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1); uses an RNA template.

POLR2A

GO:0003972

MF

RNA ligase (ATP) activity

Catalysis of the reaction: ATP + ribonucleotide(n) + ribonucleotide(m) = AMP + diphosphate + ribonucleotide(n+m).

RTCB

GO:0003973

MF

(S)-2-hydroxy-acid oxidase activity

Catalysis of the reaction: (S)-2-hydroxy-acid + O2 = 2-oxo acid + hydrogen peroxide.

HAO2

GO:0003974

MF

UDP-N-acetylglucosamine 4-epimerase activity

Catalysis of the reaction: UDP-N-acetyl-D-glucosamine = UDP-N-acetyl-D-galactosamine.

GALE

GO:0003976

MF

UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity

Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + lysosomal-enzyme D-mannose = UMP + lysosomal-enzyme N-acetyl-D-glucosaminyl-phospho-D-mannose.

GNPTAB, GNPTG

GO:0003977

MF

UDP-N-acetylglucosamine diphosphorylase activity

Catalysis of the reaction: N-acetyl-alpha-D-glucosamine 1-phosphate + UTP = diphosphate + UDP-N-acetyl-alpha-D-glucosamine.

UAP1

GO:0003978

MF

UDP-glucose 4-epimerase activity

Catalysis of the reaction: UDP-glucose = UDP-galactose.

GALE

GO:0003979

MF

UDP-glucose 6-dehydrogenase activity

Catalysis of the reaction: H(2)O + 2 NAD(+) + UDP-alpha-D-glucose = 3 H(+) + 2 NADH + UDP-alpha-D-glucuronate.

UGDH

GO:0003980

MF

UDP-glucose:glycoprotein glucosyltransferase activity

Catalysis of the addition of UDP-glucose on to asparagine-linked (N-linked) oligosaccharides of the form Man7-9GlcNAc2 on incorrectly folded glycoproteins.

UGGT1

GO:0003983

MF

UTP:glucose-1-phosphate uridylyltransferase activity

Catalysis of the reaction: alpha-D-glucose 1-phosphate + UTP = diphosphate + UDP-D-glucose.

UGP2

GO:0003985

MF

acetyl-CoA C-acetyltransferase activity

Catalysis of the reaction: 2 acetyl-CoA = CoA + acetoacetyl-CoA.

ACAT2

GO:0003986

MF

acetyl-CoA hydrolase activity

Catalysis of the reaction: acetyl-CoA + H(2)O = acetate + CoA + H(+).

ACOT8, NUDT7, ACOT9

GO:0003987

MF

acetate-CoA ligase activity

Catalysis of the reaction: ATP + acetate + CoA = AMP + diphosphate + acetyl-CoA.

ACSS3, ACSS2, ACSS1

GO:0003988

MF

acetyl-CoA C-acyltransferase activity

Catalysis of the reaction: acyl-CoA + acetyl-CoA = CoA + 3-oxoacyl-CoA.

HADHB

GO:0003989

MF

acetyl-CoA carboxylase activity

Catalysis of the reaction: ATP + acetyl-CoA + HCO3- = ADP + phosphate + malonyl-CoA.

ACACB

GO:0003993

MF

acid phosphatase activity

Catalysis of the reaction: an orthophosphoric monoester + H2O = an alcohol + phosphate, with an acid pH optimum.

ACPP, PPIP5K1, PXYLP1, ACP6, MINPP1

GO:0003994

MF

aconitate hydratase activity

Catalysis of the reaction: citrate = isocitrate. The reaction occurs in two steps: (1) citrate = cis-aconitate + H2O, (2) cis-aconitate + H2O = isocitrate. This reaction is the interconversion of citrate and isocitrate via the labile, enzyme-bound intermediate cis-aconitate. Water is removed from one part of the citrate molecule and added back to a different atom to form isocitrate.

ACO2

GO:0003995

MF

acyl-CoA dehydrogenase activity

Catalysis of the reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor.

ACOX3, ACADSB, ACADVL, ACOX1, ACOX2

GO:0003997

MF

acyl-CoA oxidase activity

Catalysis of the reaction: acyl-CoA + O2 = trans-2,3-dehydroacyl-CoA + hydrogen peroxide.

ACOX1, ACOX2

GO:0003998

MF

acylphosphatase activity

Catalysis of the reaction: an acyl phosphate + H2O = a carboxylate + phosphate.

ACYP1

GO:0003999

MF

adenine phosphoribosyltransferase activity

Catalysis of the reaction: AMP + diphosphate = adenine + 5-phospho-alpha-D-ribose 1-diphosphate.

APRT

GO:0004000

MF

adenosine deaminase activity

Catalysis of the reaction: adenosine + H2O = inosine + NH3.

ADA

GO:0004003

MF

ATP-dependent DNA helicase activity

Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction drives the unwinding of the DNA helix.

DDX3X, CHD1, CHD2, NBN, XRCC5, ERCC2, MCM4, MCM7, RECQL, MRE11A, BLM, G3BP1, MCM6, CHD4, CHD1L, FBXO18, GTF2H4, RAD50, RUVBL2

GO:0004004

MF

ATP-dependent RNA helicase activity

Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction drives the unwinding of an RNA helix.

DDX39A, DDX3X, DHX15, DHX16, DDX5, EIF4A1, G3BP1, EIF4A2, DDX46, DHX30, DHX32, DHX29, DHX40, DHX37, SUPV3L1, TDRD9, DDX54, DDX17, DDX27, DDX23, DDX24, DDX47, DHX36, DHX35, YTHDC2, DDX31, DDX28, DDX43, DDX20, DDX52, DDX49

GO:0004012

MF

phospholipid-translocating ATPase activity

Catalysis of the movement of phospholipids from one membrane bilayer leaflet to the other, driven by the hydrolysis of ATP.

ATP8B1, ATP9A, ATP8B4, ATP11B

GO:0004013

MF

adenosylhomocysteinase activity

Catalysis of the reaction: S-adenosyl-L-homocysteine + H2O = adenosine + L-homocysteine.

AHCY

GO:0004014

MF

adenosylmethionine decarboxylase activity

Catalysis of the reaction: S-adenosyl-L-methionine + H(+) = S-adenosylmethioninamine + CO(2).

AMD1

GO:0004016

MF

adenylate cyclase activity

Catalysis of the reaction: ATP = 3',5'-cyclic AMP + diphosphate.

ADCY3, ADCY9, ADCY7

GO:0004017

MF

adenylate kinase activity

Catalysis of the reaction: ATP + AMP = 2 ADP.

AK1, AK4, RAD50, AK8

GO:0004018

MF

N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity

Catalysis of the reaction: N6-(1,2-dicarboxyethyl)AMP = fumarate + AMP.

ADSL

GO:0004019

MF

adenylosuccinate synthase activity

Catalysis of the reaction: L-aspartate + GTP + IMP = N(6)-(1,2-dicarboxyethyl)-AMP + GDP + 3 H(+) + phosphate.

ADSS, ADSSL1

GO:0004020

MF

adenylylsulfate kinase activity

Catalysis of the reaction: ATP + adenylylsulfate = ADP + 3'-phosphoadenosine 5'-phosphosulfate.

PAPSS2

GO:0004021

MF

L-alanine:2-oxoglutarate aminotransferase activity

Catalysis of the reaction: 2-oxoglutarate + L-alanine = L-glutamate + pyruvate.

GPT2

GO:0004022

MF

alcohol dehydrogenase (NAD) activity

Catalysis of the reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+.

ADH7, DHRS9

GO:0004024

MF

alcohol dehydrogenase activity, zinc-dependent

Catalysis of the reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+, requiring the presence of zinc.

ADH1B, ADH7

GO:0004028

MF

3-chloroallyl aldehyde dehydrogenase activity

Catalysis of the reaction: 3-chloroallyl aldehyde + H2O = 2 H+ + 2 e- + 3-chloroacrylic acid.

ALDH1A2, ALDH3B2, ALDH9A1, ALDH3A2

GO:0004029

MF

aldehyde dehydrogenase (NAD) activity

Catalysis of the reaction: an aldehyde + NAD+ + H2O = an acid + NADH + H+.

ALDH1L1, ALDH1A2, ALDH1A1, ALDH2, ALDH1B1, ALDH1A3, ALDH3B2, ALDH9A1, ALDH7A1, ALDH3A2, ALDH6A1, ALDH1L2, ALDH8A1

GO:0004030

MF

aldehyde dehydrogenase [NAD(P)+] activity

Catalysis of the reaction: an aldehyde + NAD(P)+ + H2O = an acid + NAD(P)H + H+.

ALDH2, ALDH1A3, ALDH3B2, ALDH3A2

GO:0004031

MF

aldehyde oxidase activity

Catalysis of the reaction: an aldehyde + H2O + O2 = a carboxylic acid + hydrogen peroxide.

ADH7, AOX1

GO:0004032

MF

alditol:NADP+ 1-oxidoreductase activity

Catalysis of the reaction: an alditol + NADP+ = an aldose + NADPH + H+.

AKR7A2, AKR1B1, AKR1C3, AKR1C2, AKR1C1

GO:0004033

MF

aldo-keto reductase (NADP) activity

Catalysis of the reaction: an alcohol + NADP+ = an aldehyde or a ketone + NADPH + H+.

AKR7A2, CYB5A, AKR1B1, AKR1C3, AKR1C1, MIOX

GO:0004035

MF

alkaline phosphatase activity

Catalysis of the reaction: an orthophosphoric monoester + H2O = an alcohol + phosphate, with an alkaline pH optimum.

ALPL

GO:0004043

MF

L-aminoadipate-semialdehyde dehydrogenase activity

Catalysis of the reaction: L-2-aminoadipate 6-semialdehyde + NADP+ + H2O = L-2-aminoadipate + NADPH + H+.

ALDH7A1

GO:0004044

MF

amidophosphoribosyltransferase activity

Catalysis of the reaction: 5-phospho-beta-D-ribosylamine + L-glutamate + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + L-glutamine + H(2)O.

PPAT

GO:0004045

MF

aminoacyl-tRNA hydrolase activity

Catalysis of the reaction: N-substituted aminoacyl-tRNA + H2O = N-substituted amino acid + tRNA.

ICT1, PTRHD1, C12orf65

GO:0004046

MF

aminoacylase activity

Catalysis of the reaction: an N-acyl-L-amino acid + H2O = a carboxylate + an L-amino acid.

DARS

GO:0004047

MF

aminomethyltransferase activity

Catalysis of the reaction: (6S)-tetrahydrofolate + S-aminomethyldihydrolipoylprotein = (6R)-5,10-methylenetetrahydrofolate + NH3 + dihydrolipoylprotein.

GCSH

GO:0004051

MF

arachidonate 5-lipoxygenase activity

Catalysis of the reaction: arachidonate + O2 = (6E,8Z,11Z,14Z)-(5S)-5-hydroperoxycosa-6,8,11,14-tetraenoate.

ALOX5

GO:0004052

MF

arachidonate 12-lipoxygenase activity

Catalysis of the reaction: arachidonate + O(2) = (5Z,8Z,10E,12S,14Z)-12-hydroperoxyicosa-5,8,10,14-tetraenoate.

ALOX15

GO:0004055

MF

argininosuccinate synthase activity

Catalysis of the reaction: ATP + L-citrulline + L-aspartate = AMP + diphosphate + (N(omega)-L-arginino)succinate.

ASS1

GO:0004062

MF

aryl sulfotransferase activity

Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + a phenol = adenosine 3',5'-bisphosphate + an aryl sulfate.

SULT1A3, SULT2A1

GO:0004063

MF

aryldialkylphosphatase activity

Catalysis of the reaction: aryl dialkyl phosphate + H2O = dialkyl phosphate + an aryl alcohol.

PON1

GO:0004064

MF

arylesterase activity

Catalysis of the reaction: a phenyl acetate + H2O = a phenol + acetate.

CA2, PON1, APMAP

GO:0004065

MF

arylsulfatase activity

Catalysis of the reaction: a phenol sulfate + H2O = a phenol + sulfate.

ARSA, ARSB, ARSD, ARSK, SULF2, SULF1

GO:0004066

MF

asparagine synthase (glutamine-hydrolyzing) activity

Catalysis of the reaction: ATP + L-aspartate + L-glutamine = AMP + diphosphate + L-asparagine + L-glutamate.

ASNS

GO:0004067

MF

asparaginase activity

Catalysis of the reaction: L-asparagine + H2O = L-aspartate + NH3.

ASRGL1