Gene Symbol | GPD2 |
Entrez ID | 2820 |
Uniprot ID | P43304 |
Description | glycerol-3-phosphate dehydrogenase 2 |
Chromosomal Location | chr2: 156,435,290-156,613,735 |
Ontology | GO ID | GO Term | Definition | Evidence |
---|---|---|---|---|
BP |
GO:0006072 |
glycerol-3-phosphate metabolic process |
The chemical reactions and pathways involving glycerol-3-phosphate, a phosphoric monoester of glycerol. |
IEA |
BP |
GO:0006094 |
gluconeogenesis |
The formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol. |
IEA |
BP |
GO:0019563 |
glycerol catabolic process |
The chemical reactions and pathways resulting in the breakdown of glycerol, 1,2,3-propanetriol, a sweet, hygroscopic, viscous liquid, widely distributed in nature as a constituent of many lipids. |
IEA |
BP |
GO:0035264 |
multicellular organism growth |
The increase in size or mass of an entire multicellular organism, as opposed to cell growth. |
IEA |
BP |
GO:0043010 |
camera-type eye development |
The process whose specific outcome is the progression of the camera-type eye over time, from its formation to the mature structure. The camera-type eye is an organ of sight that receives light through an aperture and focuses it through a lens, projecting it on a photoreceptor field. |
IEA |
BP |
GO:0044255 |
cellular lipid metabolic process |
The chemical reactions and pathways involving lipids, as carried out by individual cells. |
TAS |
BP |
GO:0055114 |
oxidation-reduction process |
A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons. |
IEA |
CC |
GO:0005743 |
mitochondrial inner membrane |
The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae. |
TAS |
CC |
GO:0009331 |
glycerol-3-phosphate dehydrogenase complex |
An enzyme complex that catalyzes the dehydrogenation of sn-glycerol 3-phosphate to form glycerone phosphate. |
IEA |
MF |
GO:0004368 |
glycerol-3-phosphate dehydrogenase activity |
Catalysis of the reaction: sn-glycerol 3-phosphate + a quinone = glycerone phosphate + a quinol. |
TAS |
MF |
GO:0005509 |
calcium ion binding |
Interacting selectively and non-covalently with calcium ions (Ca2+). |
IEA |
MF |
GO:0052591 |
sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity |
Catalysis of the reaction: sn-glycerol 3-phosphate + ubiquinone-8 = glycerone phosphate + ubiquinol-8. |
IEA |
Domain ID | Description |
---|---|
IPR000447 |
FAD-dependent glycerol-3-phosphate dehydrogenase |
IPR002048 |
EF-hand domain |
IPR006076 |
FAD dependent oxidoreductase |
IPR011992 |
EF-hand domain pair |
IPR018247 |
EF-Hand 1, calcium-binding site |
IPR023753 |
FAD/NAD(P)-binding domain |
IPR031656 |
Alpha-glycerophosphate oxidase, C-terminal |
Pathway ID | Pathway Term | Pathway Source |
---|---|---|
hsa00564 |
Glycerophospholipid metabolism |
KEGG |
WP143 |
Fatty Acid Beta Oxidation |
WikiPathways |
h_etcPathway |
Electron Transport Reaction in Mitochondria |
BioCarta |
UMLS CUI | UMLS Term |
---|---|
C0011853 |
Diabetes Mellitus, Experimental |
C0011860 |
Diabetes Mellitus, Non-Insulin-Dependent |
C0026603 |
Motion Sickness |
C0029456 |
Osteoporosis |
Tissue | Cell Type |
---|---|
adrenal gland |
glandular cells |
appendix |
glandular cells |
breast |
glandular cells |
breast |
myoepithelial cells |
bronchus |
respiratory epithelial cells |
cerebellum |
cells in granular layer |
cervix, uterine |
glandular cells |
colon |
glandular cells |
duodenum |
glandular cells |
endometrium |
glandular cells |
esophagus |
squamous epithelial cells |
fallopian tube |
glandular cells |
gallbladder |
glandular cells |
hippocampus |
neuronal cells |
kidney |
cells in tubules |
lung |
macrophages |
lung |
pneumocytes |
nasopharynx |
respiratory epithelial cells |
oral mucosa |
squamous epithelial cells |
pancreas |
exocrine glandular cells |
parathyroid gland |
glandular cells |
placenta |
trophoblastic cells |
prostate |
glandular cells |
rectum |
glandular cells |
salivary gland |
glandular cells |
skin |
keratinocytes |
skin |
Langerhans |
skin |
melanocytes |
skin |
epidermal cells |
small intestine |
glandular cells |
stomach |
glandular cells |
testis |
Leydig cells |
tonsil |
squamous epithelial cells |
urinary bladder |
urothelial cells |
vagina |
squamous epithelial cells |
Pubmed ID | Author | Year | Title |
---|---|---|---|
22617121 |
Ouandaogo et al. |
2012 |
Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation |
Gene Symbol | Entrez ID | Uniprot ID | Score |
---|---|---|---|
MT-CO2 |
4513 |
P00403 |
0.49 |
ALDOA |
226 |
P04075 |
0.62 |
E2F3 |
1871 |
O00716 |
0.07 |
ACO2 |
50 |
Q99798 |
0.49 |
SDHB |
6390 |
P21912 |
0.49 |
FAF2 |
23197 |
Q96CS3 |
0.49 |
UQCRQ |
27089 |
O14949 |
0.49 |
MDM2 |
4193 |
Q00987 |
0.63 |
NTRK1 |
4914 |
P04629 |
0.63 |
PARK2 |
5071 |
O60260 |
0.63 |
SLC8A3 |
6547 |
P57103 |
0.63 |
SUMO2 |
6613 |
P61956 |
0.63 |
TRAPPC10 |
7109 |
P48553 |
0.63 |
CUL7 |
9820 |
Q14999 |
0.63 |
HAX1 |
10456 |
O00165 |
0.63 |
NUFIP1 |
26747 |
Q9UHK0 |
0.63 |
SLC39A4 |
55630 |
Q6P5W5 |
0.63 |
WDFY2 |
115825 |
Q96P53 |
0.63 |