Protein Description

Gene Symbol GPD2
Entrez ID 2820
Uniprot ID P43304
Description glycerol-3-phosphate dehydrogenase 2
Chromosomal Location chr2: 156,435,290-156,613,735
Ontology GO ID GO Term Definition Evidence

BP

GO:0006072

glycerol-3-phosphate metabolic process

The chemical reactions and pathways involving glycerol-3-phosphate, a phosphoric monoester of glycerol.

IEA

BP

GO:0006094

gluconeogenesis

The formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol.

IEA

BP

GO:0019563

glycerol catabolic process

The chemical reactions and pathways resulting in the breakdown of glycerol, 1,2,3-propanetriol, a sweet, hygroscopic, viscous liquid, widely distributed in nature as a constituent of many lipids.

IEA

BP

GO:0035264

multicellular organism growth

The increase in size or mass of an entire multicellular organism, as opposed to cell growth.

IEA

BP

GO:0043010

camera-type eye development

The process whose specific outcome is the progression of the camera-type eye over time, from its formation to the mature structure. The camera-type eye is an organ of sight that receives light through an aperture and focuses it through a lens, projecting it on a photoreceptor field.

IEA

BP

GO:0044255

cellular lipid metabolic process

The chemical reactions and pathways involving lipids, as carried out by individual cells.

TAS

BP

GO:0055114

oxidation-reduction process

A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.

IEA

CC

GO:0005743

mitochondrial inner membrane

The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.

TAS

CC

GO:0009331

glycerol-3-phosphate dehydrogenase complex

An enzyme complex that catalyzes the dehydrogenation of sn-glycerol 3-phosphate to form glycerone phosphate.

IEA

MF

GO:0004368

glycerol-3-phosphate dehydrogenase activity

Catalysis of the reaction: sn-glycerol 3-phosphate + a quinone = glycerone phosphate + a quinol.

TAS

MF

GO:0005509

calcium ion binding

Interacting selectively and non-covalently with calcium ions (Ca2+).

IEA

MF

GO:0052591

sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity

Catalysis of the reaction: sn-glycerol 3-phosphate + ubiquinone-8 = glycerone phosphate + ubiquinol-8.

IEA

Domain ID Description

IPR000447

FAD-dependent glycerol-3-phosphate dehydrogenase

IPR002048

EF-hand domain

IPR006076

FAD dependent oxidoreductase

IPR011992

EF-hand domain pair

IPR018247

EF-Hand 1, calcium-binding site

IPR023753

FAD/NAD(P)-binding domain

IPR031656

Alpha-glycerophosphate oxidase, C-terminal

Pathway ID Pathway Term Pathway Source

hsa00564

Glycerophospholipid metabolism

KEGG

WP143

Fatty Acid Beta Oxidation

WikiPathways

h_etcPathway

Electron Transport Reaction in Mitochondria

BioCarta

UMLS CUI UMLS Term

C0011853

Diabetes Mellitus, Experimental

C0011860

Diabetes Mellitus, Non-Insulin-Dependent

C0026603

Motion Sickness

C0029456

Osteoporosis

Tissue Cell Type

adrenal gland

glandular cells

appendix

glandular cells

breast

glandular cells

breast

myoepithelial cells

bronchus

respiratory epithelial cells

cerebellum

cells in granular layer

cervix, uterine

glandular cells

colon

glandular cells

duodenum

glandular cells

endometrium

glandular cells

esophagus

squamous epithelial cells

fallopian tube

glandular cells

gallbladder

glandular cells

hippocampus

neuronal cells

kidney

cells in tubules

lung

macrophages

lung

pneumocytes

nasopharynx

respiratory epithelial cells

oral mucosa

squamous epithelial cells

pancreas

exocrine glandular cells

parathyroid gland

glandular cells

placenta

trophoblastic cells

prostate

glandular cells

rectum

glandular cells

salivary gland

glandular cells

skin

keratinocytes

skin

Langerhans

skin

melanocytes

skin

epidermal cells

small intestine

glandular cells

stomach

glandular cells

testis

Leydig cells

tonsil

squamous epithelial cells

urinary bladder

urothelial cells

vagina

squamous epithelial cells

No databases found.

Pubmed ID Author Year Title

22617121

Ouandaogo et al.

2012

Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation

Gene Symbol Entrez ID Uniprot ID Score

MT-CO2

4513

P00403

0.49

ALDOA

226

P04075

0.62

E2F3

1871

O00716

0.07

ACO2

50

Q99798

0.49

SDHB

6390

P21912

0.49

FAF2

23197

Q96CS3

0.49

UQCRQ

27089

O14949

0.49

MDM2

4193

Q00987

0.63

NTRK1

4914

P04629

0.63

PARK2

5071

O60260

0.63

SLC8A3

6547

P57103

0.63

SUMO2

6613

P61956

0.63

TRAPPC10

7109

P48553

0.63

CUL7

9820

Q14999

0.63

HAX1

10456

O00165

0.63

NUFIP1

26747

Q9UHK0

0.63

SLC39A4

55630

Q6P5W5

0.63

WDFY2

115825

Q96P53

0.63