Protein Description

Gene Symbol GNL1
Entrez ID 2794
Uniprot ID P36915
Description guanine nucleotide binding protein-like 1
Chromosomal Location chr6: 30,541,377-30,557,174
Ontology GO ID GO Term Definition Evidence

BP

GO:0002456

T cell mediated immunity

Any process involved in the carrying out of an immune response by a T cell.

NAS

BP

GO:0006974

cellular response to DNA damage stimulus

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.

IDA

BP

GO:0007165

signal transduction

The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.

NAS

BP

GO:0042254

ribosome biogenesis

A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits; includes transport to the sites of protein synthesis.

IBA

CC

GO:0005615

extracellular space

That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.

NAS

CC

GO:0005634

nucleus

A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

IDA

MF

GO:0003924

GTPase activity

Catalysis of the reaction: GTP + H2O = GDP + phosphate.

IBA

MF

GO:0005198

structural molecule activity

The action of a molecule that contributes to the structural integrity of a complex or assembly within or outside a cell.

NAS

MF

GO:0005525

GTP binding

Interacting selectively and non-covalently with GTP, guanosine triphosphate.

NAS

Domain ID Description

IPR006073

GTP binding domain

IPR027417

P-loop containing nucleoside triphosphate hydrolase

IPR030378

Circularly permuted (CP)-type guanine nucleotide-binding (G) domain

No pathways found.

No diseases found.

No tissues found.

No databases found.

Pubmed ID Author Year Title

22951915

Haozi et al.

2012

Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome

Gene Symbol Entrez ID Uniprot ID Score

RPL5

6125

P46777

0.49

RPS15A

6210

P62244

0.59

ZNF212

7988

Q9UDV6

0.63

HNRNPC

3183

P07910

0.49

KPNA4

3839

O00629

0.49

RANGAP1

5905

P46060

0.49

RPL7

6129

P18124

0.49

RPLP0

6175

P05388

0.49

PABPC4

8761

Q13310

0.49

HUWE1

10075

Q7Z6Z7

0.49

ALYREF

10189

Q86V81

0.49

KRR1

11103

Q13601

0.49

NOP58

51602

Q9Y2X3

0.49

DDX18

8886

Q9NVP1

0.56

EIF5B

9669

O60841

0.56

PES1

23481

O00541

0.56

ALDOC

230

P09972

0.63

GDI1

2664

P31150

0.63

NTRK1

4914

P04629

0.63

RAD21

5885

O60216

0.63

SUMO1

7341

P63165

0.63

PTP4A1

7803

Q93096

0.63