| Gene Symbol | GBP3 |
| Entrez ID | 2635 |
| Uniprot ID | Q9H0R5 |
| Description | guanylate binding protein 3 |
| Chromosomal Location | chr1: 89,006,666-89,022,894 |
| Ontology | GO ID | GO Term | Definition | Evidence |
|---|---|---|---|---|
|
BP |
GO:0051607 |
defense response to virus |
Reactions triggered in response to the presence of a virus that act to protect the cell or organism. |
IEA |
|
CC |
GO:0000139 |
Golgi membrane |
The lipid bilayer surrounding any of the compartments of the Golgi apparatus. |
IEA |
|
CC |
GO:0048471 |
perinuclear region of cytoplasm |
Cytoplasm situated near, or occurring around, the nucleus. |
IEA |
|
MF |
GO:0003924 |
GTPase activity |
Catalysis of the reaction: GTP + H2O = GDP + phosphate. |
IEA |
|
MF |
GO:0005515 |
protein binding |
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules). |
IPI |
|
MF |
GO:0005525 |
GTP binding |
Interacting selectively and non-covalently with GTP, guanosine triphosphate. |
IEA |
| Domain ID | Description |
|---|---|
|
IPR003191 |
Guanylate-binding protein, C-terminal |
|
IPR015894 |
Guanylate-binding protein, N-terminal |
|
IPR027417 |
P-loop containing nucleoside triphosphate hydrolase |
|
IPR030386 |
GB1/RHD3-type guanine nucleotide-binding (G) domain |
| Pathway ID | Pathway Term | Pathway Source |
|---|---|---|
|
hsa04621 |
NOD-like receptor signaling pathway |
KEGG |
| Tissue | Cell Type |
|---|---|
|
bone marrow |
hematopoietic cells |
|
caudate |
glial cells |
|
caudate |
neuronal cells |
|
cerebellum |
cells in molecular layer |
|
cerebral cortex |
glial cells |
|
epididymis |
glandular cells |
|
hippocampus |
glial cells |
|
kidney |
cells in tubules |
|
pancreas |
exocrine glandular cells |
|
parathyroid gland |
glandular cells |
|
placenta |
trophoblastic cells |
|
small intestine |
glandular cells |
|
soft tissue |
peripheral nerve |
|
stomach |
glandular cells |
| Pubmed ID | Author | Year | Title |
|---|---|---|---|
|
22951915 |
Haozi et al. |
2012 |
Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome |
| Gene Symbol | Entrez ID | Uniprot ID | Score |
|---|---|---|---|
|
MAP4K4 |
9448 |
O95819 |
0.79 |