Protein Description

Gene Symbol ALDH1B1
Entrez ID 219
Uniprot ID P30837
Description aldehyde dehydrogenase 1 family member B1
Chromosomal Location chr9: 38,392,664-38,398,661
Ontology GO ID GO Term Definition Evidence

BP

GO:0005975

carbohydrate metabolic process

The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. Includes the formation of carbohydrate derivatives by the addition of a carbohydrate residue to another molecule.

NAS

BP

GO:0006068

ethanol catabolic process

The chemical reactions and pathways resulting in the breakdown of ethanol, CH3-CH2-OH, a colorless, water-miscible, flammable liquid produced by alcoholic fermentation.

IEA

BP

GO:0006069

ethanol oxidation

An ethanol metabolic process in which ethanol is converted to acetyl-CoA via acetaldehyde and acetate.

TAS

CC

GO:0005654

nucleoplasm

That part of the nuclear content other than the chromosomes or the nucleolus.

IDA

CC

GO:0005739

mitochondrion

A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.

IDA

CC

GO:0005759

mitochondrial matrix

The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.

TAS

CC

GO:0043231

intracellular membrane-bounded organelle

Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.

IDA

MF

GO:0004029

aldehyde dehydrogenase (NAD) activity

Catalysis of the reaction: an aldehyde + NAD+ + H2O = an acid + NADH + H+.

IBA|TAS

Domain ID Description

IPR015590

Aldehyde dehydrogenase domain

IPR016160

Aldehyde dehydrogenase, cysteine active site

IPR016161

Aldehyde/histidinol dehydrogenase

IPR016162

Aldehyde dehydrogenase N-terminal domain

IPR029510

Aldehyde dehydrogenase, glutamic acid active site

Pathway ID Pathway Term Pathway Source

hsa00010

Glycolysis / Gluconeogenesis

KEGG

hsa00053

Ascorbate and aldarate metabolism

KEGG

hsa00071

Fatty acid degradation

KEGG

hsa00280

Valine, leucine and isoleucine degradation

KEGG

hsa00310

Lysine degradation

KEGG

hsa00330

Arginine and proline metabolism

KEGG

hsa00340

Histidine metabolism

KEGG

hsa00380

Tryptophan metabolism

KEGG

hsa00410

beta-Alanine metabolism

KEGG

hsa00561

Glycerolipid metabolism

KEGG

hsa00620

Pyruvate metabolism

KEGG

hsa01100

Metabolic pathways

KEGG

UMLS CUI UMLS Term

C0009375

Colonic Neoplasms

C0023893

Liver Cirrhosis, Experimental

Tissue Cell Type

adrenal gland

glandular cells

appendix

glandular cells

breast

glandular cells

bronchus

respiratory epithelial cells

cerebral cortex

neuronal cells

colon

endothelial cells

colon

glandular cells

colon

peripheral nerve/ganglion

duodenum

glandular cells

endometrium

glandular cells

gallbladder

glandular cells

heart muscle

myocytes

kidney

cells in tubules

liver

bile duct cells

liver

hepatocytes

lung

macrophages

lymph node

non-germinal center cells

nasopharynx

respiratory epithelial cells

pancreas

exocrine glandular cells

rectum

glandular cells

seminal vesicle

glandular cells

skin

fibroblasts

small intestine

glandular cells

soft tissue

adipocytes

stomach

glandular cells

testis

Leydig cells

urinary bladder

urothelial cells

No databases found.

Pubmed ID Author Year Title

12734205

Wood et al.

2003

The Molecular Phenotype of Polycystic Ovary Syndrome (PCOS) Theca Cells and New Candidate PCOS Genes Defined by Microarray Analysis

22951915

Haozi et al.

2012

Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome

Gene Symbol Entrez ID Uniprot ID Score

ESD

2098

P10768

0.49

PGM1

5236

P36871

0.49

SRP68

6730

Q9UHB9

0.49

UQCRB

7381

P14927

0.49

UQCRC2

7385

P22695

0.49

XPNPEP1

7511

Q9NQW7

0.49

PDCD6IP

10015

Q8WUM4

0.49

STIP1

10963

P31948

0.49

FH

2271

P07954

0.63

HEXB

3074

P07686

0.63

FEM1B

10116

Q9UK73

0.63

DHRS4

10901

Q9BTZ2

0.63

PDCD10

11235

Q9BUL8

0.63

SUFU

51684

Q9UMX1

0.63

ETFA

2108

P13804

0.49

LDHA

3939

P00338

0.49

LDHB

3945

P07195

0.49

OAT

4942

P04181

0.49

SOD2

6648

P04179

0.49

UQCRFS1

7386

P47985

0.49

ALDH5A1

7915

P51649

0.49

OFD1

8481

O75665

0.49

HIBADH

11112

P31937

0.49

TCTN3

26123

Q6NUS6

0.49

UQCRQ

27089

O14949

0.49

RPL6

6128

Q02878

0.56

ECT2

1894

Q9H8V3

0.63

FABP2

2169

P12104

0.63

ICT1

3396

Q14197

0.63

JUN

3725

P05412

0.63

NTRK1

4914

P04629

0.63

EXOSC10

5394

Q01780

0.63

CUL3

8452

Q13618

0.63

XRN2

22803

Q9H0D6

0.63

FBXO6

26270

Q9NRD1

0.63

UBR7

55148

Q8N806

0.63

OGFOD1

55239

Q8N543

0.63

MAP1LC3B

81631

Q9GZQ8

0.63

TATDN1

83940

Q6P1N9

0.63

MAP1LC3A

84557

Q9H492

0.63

FN1

2335

P02751

0.72

HDAC1

3065

Q13547

0.72

LLGL1

3996

Q15334

0.72

MYC

4609

P01106

0.72

ATL3

25923

Q6DD88

0.72

SGO1

151648

Q5FBB7

0.72