| Gene Symbol | RNASEK |
| Entrez ID | 440400 |
| Uniprot ID | Q6P5S7 |
| Description | ribonuclease, RNase K |
| Chromosomal Location | chr17: 7,012,417-7,014,532 |
| Ontology | GO ID | GO Term | Definition | Evidence |
|---|---|---|---|---|
|
BP |
GO:0009303 |
rRNA transcription |
The synthesis of ribosomal RNA (rRNA), any RNA that forms part of the ribosomal structure, from a DNA template. |
IDA |
|
BP |
GO:0090502 |
RNA phosphodiester bond hydrolysis, endonucleolytic |
The chemical reactions and pathways involving the hydrolysis of internal 3',5'-phosphodiester bonds in one or two strands of ribonucleotides. |
IEA |
|
CC |
GO:0005575 |
cellular_component |
The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together. |
ND |
|
CC |
GO:0016021 |
integral component of membrane |
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
IEA |
|
MF |
GO:0004521 |
endoribonuclease activity |
Catalysis of the hydrolysis of ester linkages within ribonucleic acid by creating internal breaks. |
IDA |
| Domain ID | Description |
|---|---|
|
IPR026770 |
Ribonuclease kappa |
| Tissue | Cell Type |
|---|---|
|
adrenal gland |
glandular cells |
|
caudate |
neuronal cells |
|
cerebellum |
Purkinje cells |
|
duodenum |
glandular cells |
|
kidney |
cells in tubules |
|
pancreas |
exocrine glandular cells |
|
parathyroid gland |
glandular cells |
|
placenta |
decidual cells |
|
skeletal muscle |
myocytes |
|
small intestine |
glandular cells |
|
stomach |
glandular cells |
| Pubmed ID | Author | Year | Title |
|---|---|---|---|
|
22617121 |
Ouandaogo et al. |
2012 |
Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation |
|
22951915 |
Haozi et al. |
2012 |
Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome |