| Gene Symbol | RNASEK |
| Entrez ID | 440400 |
| Uniprot ID | Q6P5S7 |
| Description | ribonuclease, RNase K |
| Chromosomal Location | chr17: 7,012,417-7,014,532 |
| Ontology | GO ID | GO Term | Definition | Evidence |
|---|---|---|---|---|
BP | GO:0009303 | rRNA transcription |
The synthesis of ribosomal RNA (rRNA), any RNA that forms part of the ribosomal structure, from a DNA template. | IDA |
BP | GO:0090502 | RNA phosphodiester bond hydrolysis, endonucleolytic |
The chemical reactions and pathways involving the hydrolysis of internal 3',5'-phosphodiester bonds in one or two strands of ribonucleotides. | IEA |
CC | GO:0005575 | cellular_component |
The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together. | ND |
CC | GO:0016021 | integral component of membrane |
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. | IEA |
MF | GO:0004521 | endoribonuclease activity |
Catalysis of the hydrolysis of ester linkages within ribonucleic acid by creating internal breaks. | IDA |
| Domain ID | Description |
|---|---|
IPR026770 | Ribonuclease kappa |
| Tissue | Cell Type |
|---|---|
adrenal gland | glandular cells |
caudate | neuronal cells |
cerebellum | Purkinje cells |
duodenum | glandular cells |
kidney | cells in tubules |
pancreas | exocrine glandular cells |
parathyroid gland | glandular cells |
placenta | decidual cells |
skeletal muscle | myocytes |
small intestine | glandular cells |
stomach | glandular cells |
| Pubmed ID | Author | Year | Title |
|---|---|---|---|
22617121 | Ouandaogo et al. | 2012 | Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation |
22951915 | Haozi et al. | 2012 | Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome |