Gene Symbol | CCDC103 |
Entrez ID | 388389 |
Uniprot ID | Q8IW40 |
Description | coiled-coil domain containing 103 |
Chromosomal Location | chr17: 44,899,142-44,905,390 |
Ontology | GO ID | GO Term | Definition | Evidence |
---|---|---|---|---|
BP |
GO:0001947 |
heart looping |
The tube morphogenesis process in which the primitive heart tube loops asymmetrically. This looping brings the primitive heart chambers into alignment preceding their future integration. Heart looping begins with dextral-looping and ends when the main regional divisions of the mature heart and primordium of the great arterial trunks become established preceeding septation. |
IMP |
BP |
GO:0003341 |
cilium movement |
The directed, self-propelled movement of a cilium. |
IGI |
BP |
GO:0036158 |
outer dynein arm assembly |
The aggregation, arrangement and bonding together of a set of components to form an axonemal dynein outer arm, an outer arm structure present on the outer doublet microtubules of ciliary and flagellar axonemes. |
IGI |
BP |
GO:0036159 |
inner dynein arm assembly |
The aggregation, arrangement and bonding together of a set of components to form an axonemal dynein inner arm, an inner arm structure present on the outer doublet microtubules of ciliary and flagellar axonemes. |
IGI |
BP |
GO:0060287 |
epithelial cilium movement involved in determination of left/right asymmetry |
The movement of cilia of epithelial cells resulting in the transport of signals which determine asymmetry in an organism's body plan with respect to the left and right halves. |
IC |
BP |
GO:0070286 |
axonemal dynein complex assembly |
The aggregation, arrangement and bonding together of a set of components to form an axonemal dynein complex, a dynein complex found in eukaryotic cilia and flagella, in which the motor domain heads interact with adjacent microtubules to generate a sliding force which is converted to a bending motion. |
IMP |
BP |
GO:0071907 |
determination of digestive tract left/right asymmetry |
Determination of the asymmetric location of various parts of the digestive tract with respect to the left and right halves of the organism. The digestive tract is the anatomical structure through which food passes and is processed. |
IMP |
CC |
GO:0005737 |
cytoplasm |
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
ISS |
CC |
GO:0005930 |
axoneme |
The bundle of microtubules and associated proteins that forms the core of cilia (also called flagella) in eukaryotic cells and is responsible for their movements. |
ISS |
CC |
GO:0031514 |
motile cilium |
A cilium which has a variable arrangement of axonemal microtubules, contains molecular motors, and beats with a characteristic whip-like pattern that promotes cell motility or transport of fluids and other cells across a cell surface. Motile cilia are typically found in multiple copies on epithelial cells that line the lumenal ducts of various tissues. Motile cilia may also function as sensory organelles. |
IEA |
MF |
GO:0005515 |
protein binding |
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules). |
IPI |
MF |
GO:0042803 |
protein homodimerization activity |
Interacting selectively and non-covalently with an identical protein to form a homodimer. |
IDA |
Domain ID | Description |
---|---|
IPR025986 |
RNA-polymerase II-associated protein 3-like, C-terminal domain |
IPR031733 |
Dynein attachment factor, N-terminal |
UMLS CUI | UMLS Term |
---|---|
C0022521 |
Kartagener Syndrome |
Tissue | Cell Type |
---|---|
heart muscle |
myocytes |
smooth muscle |
smooth muscle cells |
Pubmed ID | Author | Year | Title |
---|---|---|---|
26459919 |
Lan et al. |
2015 |
Functional microarray analysis of differentially expressed genes in granulosa cells from women with polycystic ovary syndrome related to MAPK/ERK signaling |
Gene Symbol | Entrez ID | Uniprot ID | Score |
---|---|---|---|
MEOX2 |
4223 |
P50222 |
0.63 |
HGS |
9146 |
O14964 |
0.63 |
RUVBL2 |
10856 |
Q9Y230 |
0.63 |
R3HCC1L |
27291 |
Q7Z5L2 |
0.63 |
VAC14 |
55697 |
Q08AM6 |
0.63 |