Gene Symbol | MAST4 |
Entrez ID | 375449 |
Uniprot ID | O15021 |
Description | microtubule associated serine/threonine kinase family member 4 |
Chromosomal Location | chr5: 66,596,361-67,169,595 |
Ontology | GO ID | GO Term | Definition | Evidence |
---|---|---|---|---|
BP |
GO:0018105 |
peptidyl-serine phosphorylation |
The phosphorylation of peptidyl-serine to form peptidyl-O-phospho-L-serine. |
IBA |
BP |
GO:0035556 |
intracellular signal transduction |
The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell. |
IBA |
CC |
GO:0005622 |
intracellular |
The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm. |
IBA |
CC |
GO:0005737 |
cytoplasm |
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
IEA |
MF |
GO:0000287 |
magnesium ion binding |
Interacting selectively and non-covalently with magnesium (Mg) ions. |
IEA |
MF |
GO:0004674 |
protein serine/threonine kinase activity |
Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate. |
IBA |
MF |
GO:0005524 |
ATP binding |
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
IEA |
Domain ID | Description |
---|---|
IPR000719 |
Protein kinase domain |
IPR000961 |
AGC-kinase, C-terminal |
IPR001478 |
PDZ domain |
IPR008271 |
Serine/threonine-protein kinase, active site |
IPR011009 |
Protein kinase-like domain |
IPR015022 |
Microtubule-associated serine/threonine-protein kinase, domain |
IPR023142 |
Microtubule-associated serine/threonine-protein kinase, pre-PK domain |
UMLS CUI | UMLS Term |
---|---|
C0014544 |
Epilepsy |
Tissue | Cell Type |
---|---|
esophagus |
squamous epithelial cells |
urinary bladder |
urothelial cells |
Pubmed ID | Author | Year | Title |
---|---|---|---|
22617121 |
Ouandaogo et al. |
2012 |
Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation |
22951915 |
Haozi et al. |
2012 |
Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome |
Gene Symbol | Entrez ID | Uniprot ID | Score |
---|---|---|---|
EEF1A1 |
1915 |
P68104 |
0.63 |
SMAD1 |
4086 |
Q15797 |
0.63 |
MYC |
4609 |
P01106 |
0.63 |