Gene Symbol | ERH |
Entrez ID | 2079 |
Uniprot ID | P84090 |
Description | enhancer of rudimentary homolog (Drosophila) |
Chromosomal Location | chr14: 69,380,123-69,398,627 |
Ontology | GO ID | GO Term | Definition | Evidence |
---|---|---|---|---|
BP |
GO:0006139 |
nucleobase-containing compound metabolic process |
Any cellular metabolic process involving nucleobases, nucleosides, nucleotides and nucleic acids. |
TAS |
BP |
GO:0006213 |
pyrimidine nucleoside metabolic process |
The chemical reactions and pathways involving any pyrimidine nucleoside, one of a family of organic molecules consisting of a pyrimidine base covalently bonded to ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside). |
TAS |
BP |
GO:0006221 |
pyrimidine nucleotide biosynthetic process |
The chemical reactions and pathways resulting in the formation of a pyrimidine nucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar. |
IEA |
BP |
GO:0007049 |
cell cycle |
The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division. |
IEA |
BP |
GO:0045747 |
positive regulation of Notch signaling pathway |
Any process that activates or increases the frequency, rate or extent of the Notch signaling pathway. |
IEA |
CC |
GO:0030496 |
midbody |
A thin cytoplasmic bridge formed between daughter cells at the end of cytokinesis. The midbody forms where the contractile ring constricts, and may persist for some time before finally breaking to complete cytokinesis. |
IDA |
CC |
GO:0034709 |
methylosome |
A large (20 S) protein complex that possesses protein arginine methyltransferase activity and modifies specific arginines to dimethylarginines in the arginine- and glycine-rich domains of several spliceosomal Sm proteins, thereby targeting these proteins to the survival of motor neurons (SMN) complex for assembly into small nuclear ribonucleoprotein (snRNP) core particles. Proteins found in the methylosome include the methyltransferase JBP1 (PRMT5), pICln (CLNS1A), MEP50 (WDR77), and unmethylated forms of SM proteins that have RG domains. |
IDA |
MF |
GO:0005515 |
protein binding |
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules). |
IPI |
MF |
GO:0008327 |
methyl-CpG binding |
Interacting selectively and non-covalently with a methylated cytosine/guanine dinucleotide. |
IDA |
MF |
GO:0044822 |
poly(A) RNA binding |
Interacting non-covalently with a poly(A) RNA, a RNA molecule which has a tail of adenine bases. |
IDA |
Domain ID | Description |
---|---|
IPR000781 |
Enhancer of rudimentary |
Tissue | Cell Type |
---|---|
adrenal gland |
glandular cells |
appendix |
glandular cells |
appendix |
lymphoid tissue |
breast |
adipocytes |
breast |
glandular cells |
breast |
myoepithelial cells |
bronchus |
respiratory epithelial cells |
caudate |
neuronal cells |
cerebellum |
cells in granular layer |
cerebellum |
cells in molecular layer |
cerebellum |
Purkinje cells |
cerebral cortex |
endothelial cells |
cerebral cortex |
neuronal cells |
cervix, uterine |
glandular cells |
cervix, uterine |
squamous epithelial cells |
colon |
endothelial cells |
colon |
glandular cells |
duodenum |
glandular cells |
endometrium |
glandular cells |
endometrium |
cells in endometrial stroma |
epididymis |
glandular cells |
esophagus |
squamous epithelial cells |
fallopian tube |
glandular cells |
gallbladder |
glandular cells |
hippocampus |
neuronal cells |
kidney |
cells in glomeruli |
kidney |
cells in tubules |
lung |
macrophages |
lung |
pneumocytes |
nasopharynx |
respiratory epithelial cells |
oral mucosa |
squamous epithelial cells |
ovary |
ovarian stroma cells |
parathyroid gland |
glandular cells |
placenta |
decidual cells |
placenta |
trophoblastic cells |
rectum |
glandular cells |
salivary gland |
glandular cells |
seminal vesicle |
glandular cells |
skeletal muscle |
myocytes |
skin |
fibroblasts |
skin |
keratinocytes |
skin |
Langerhans |
skin |
melanocytes |
skin |
epidermal cells |
small intestine |
glandular cells |
soft tissue |
adipocytes |
soft tissue |
fibroblasts |
soft tissue |
peripheral nerve |
stomach |
glandular cells |
testis |
cells in seminiferous ducts |
thyroid gland |
glandular cells |
urinary bladder |
urothelial cells |
Pubmed ID | Author | Year | Title |
---|---|---|---|
12734205 |
Wood et al. |
2003 |
The Molecular Phenotype of Polycystic Ovary Syndrome (PCOS) Theca Cells and New Candidate PCOS Genes Defined by Microarray Analysis |
Gene Symbol | Entrez ID | Uniprot ID | Score |
---|---|---|---|
APP |
351 |
P05067 |
0.56 |
COPS6 |
10980 |
Q7L5N1 |
0.63 |
CIZ1 |
25792 |
Q9ULV3 |
0.63 |
MED31 |
51003 |
Q9Y3C7 |
0.63 |
RBM48 |
84060 |
Q5RL73 |
0.63 |
POLDIP3 |
84271 |
Q9BY77 |
0.63 |
IGSF21 |
84966 |
Q96ID5 |
0.63 |
Q9P078_HUMAN |
N/A |
Q9P078 |
0.63 |
SH3GL2 |
6456 |
Q99962 |
0.73 |
FAM208B |
54906 |
Q5VWN6 |
0.73 |
CHTOP |
26097 |
Q9Y3Y2 |
0.82 |
CSNK2A1 |
1457 |
P68400 |
0.52 |
BMI1 |
648 |
P35226 |
0.63 |
CDK2 |
1017 |
P24941 |
0.63 |
ELAVL1 |
1994 |
Q15717 |
0.63 |
EZH2 |
2146 |
Q15910 |
0.63 |
HSPA8 |
3312 |
P11142 |
0.63 |
NOTCH1 |
4851 |
P46531 |
0.63 |
PRKAB1 |
5564 |
Q9Y478 |
0.63 |
PSPH |
5723 |
P78330 |
0.63 |
RNF2 |
6045 |
Q99496 |
0.63 |
TERF2 |
7014 |
Q15554 |
0.63 |
TLE1 |
7088 |
Q04724 |
0.63 |
TRAF6 |
7189 |
Q9Y4K3 |
0.63 |
UBL4A |
8266 |
P11441 |
0.63 |
HIST1H3A |
8350 |
P68431 |
0.63 |
EED |
8726 |
O75530 |
0.63 |
UNC119 |
9094 |
Q13432 |
0.63 |
RPS6KA5 |
9252 |
O75582 |
0.63 |
KIAA0101 |
9768 |
Q15004 |
0.63 |
SETDB1 |
9869 |
Q15047 |
0.63 |
RNPS1 |
10921 |
Q15287 |
0.63 |
PAXIP1 |
22976 |
Q6ZW49 |
0.63 |
SUZ12 |
23512 |
Q15022 |
0.63 |
ASB3 |
51130 |
Q9Y575 |
0.63 |
LUZP4 |
51213 |
Q9P127 |
0.63 |
DGCR8 |
54487 |
Q8WYQ5 |
0.63 |
MAP1LC3A |
84557 |
Q9H492 |
0.63 |
ASB18 |
401036 |
Q6ZVZ8 |
0.63 |
ARRB2 |
409 |
P32121 |
0.72 |
MAGOH |
4116 |
P61326 |
0.72 |
EIF4A3 |
9775 |
P38919 |
0.72 |
ACP6 |
51205 |
Q9NPH0 |
0.72 |
BIN3 |
55909 |
Q9NQY0 |
0.72 |
SMN1; SMN2 |
6606 |
Q16637 |
0.72 |
TP53 |
7157 |
P04637 |
0.73 |
CTDP1 |
9150 |
Q9Y5B0 |
0.73 |
CSNK2A2 |
1459 |
P19784 |
0.75 |
ILK |
3611 |
Q13418 |
0.76 |
CNBP |
7555 |
P62633 |
0.76 |
EIF1B |
10289 |
O60739 |
0.76 |