Gene Symbol | ST8SIA6 |
Entrez ID | 338596 |
Uniprot ID | P61647 |
Description | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 |
Chromosomal Location | chr10: 17,318,383-17,454,330 |
Ontology | GO ID | GO Term | Definition | Evidence |
---|---|---|---|---|
BP |
GO:0001574 |
ganglioside biosynthetic process |
The chemical reactions and pathways resulting in the formation of ceramide oligosaccharides carrying in addition to other sugar residues, one or more sialic acid residues. |
ISS |
BP |
GO:0006493 |
protein O-linked glycosylation |
A protein glycosylation process in which a carbohydrate or carbohydrate derivative unit is added to a protein via the hydroxyl group of peptidyl-serine, peptidyl-threonine, peptidyl-hydroxylysine, or peptidyl-hydroxyproline, or via the phenol group of peptidyl-tyrosine, forming an O-glycan. |
ISS |
BP |
GO:0009100 |
glycoprotein metabolic process |
The chemical reactions and pathways involving glycoproteins, any protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide. |
ISS |
BP |
GO:0009247 |
glycolipid biosynthetic process |
The chemical reactions and pathways resulting in the formation of glycolipid, a class of 1,2-di-O-acylglycerols joined at oxygen 3 by a glycosidic linkage to a carbohydrate part (usually a mono-, di- or tri-saccharide). |
ISS |
BP |
GO:0009311 |
oligosaccharide metabolic process |
The chemical reactions and pathways involving oligosaccharides, molecules with between two and (about) 20 monosaccharide residues connected by glycosidic linkages. |
ISS |
BP |
GO:0016051 |
carbohydrate biosynthetic process |
The chemical reactions and pathways resulting in the formation of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. |
ISS |
BP |
GO:0097503 |
sialylation |
The covalent attachment of sialic acid to a substrate molecule. |
IEA |
CC |
GO:0000139 |
Golgi membrane |
The lipid bilayer surrounding any of the compartments of the Golgi apparatus. |
TAS |
CC |
GO:0030173 |
integral component of Golgi membrane |
The component of the Golgi membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
IEA |
MF |
GO:0003828 |
alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity |
Catalysis of the reaction: CMP-N-acetylneuraminate + alpha-N-acetylneuraminyl-(2->3)-beta-D-galactosyl-R = CMP + alpha-N-acetylneuraminyl-(2->8)-alpha-N-acetylneuraminyl-(2->3)-beta-D-galactosyl-R. |
TAS |
MF |
GO:0008373 |
sialyltransferase activity |
Catalysis of the transfer of sialic acid to an acceptor molecule, typically the terminal portions of the sialylated glycolipids (gangliosides) or to the N- or O-linked sugar chains of glycoproteins. |
ISS |
Domain ID | Description |
---|---|
IPR001675 |
Glycosyl transferase family 29 |
IPR012163 |
Sialyltransferase |
Pubmed ID | Author | Year | Title |
---|---|---|---|
23824412 |
Piltonen et al. |
2013 |
Mesenchymal Stem/Progenitors and Other Endometrial Cell Types From Women With Polycystic Ovary Syndrome (PCOS) Display Inflammatory and Oncogenic Potential |