Gene Symbol | SUMF1 |
Entrez ID | 285362 |
Uniprot ID | Q8NBK3 |
Description | sulfatase modifying factor 1 |
Chromosomal Location | chr3: 3,700,814-4,467,281 |
Ontology | GO ID | GO Term | Definition | Evidence |
---|---|---|---|---|
BP |
GO:0006687 |
glycosphingolipid metabolic process |
The chemical reactions and pathways involving glycosphingolipids, any compound with residues of sphingoid and at least one monosaccharide. |
TAS |
BP |
GO:0043687 |
post-translational protein modification |
The process of covalently altering one or more amino acids in a protein after the protein has been completely translated and released from the ribosome. |
TAS |
BP |
GO:0055114 |
oxidation-reduction process |
A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons. |
IEA |
CC |
GO:0005783 |
endoplasmic reticulum |
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached). |
IBA |
CC |
GO:0005788 |
endoplasmic reticulum lumen |
The volume enclosed by the membranes of the endoplasmic reticulum. |
TAS |
MF |
GO:0016491 |
oxidoreductase activity |
Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced. |
TAS |
MF |
GO:0042803 |
protein homodimerization activity |
Interacting selectively and non-covalently with an identical protein to form a homodimer. |
IEA |
MF |
GO:0046872 |
metal ion binding |
Interacting selectively and non-covalently with any metal ion. |
IEA |
Domain ID | Description |
---|---|
IPR005532 |
Sulfatase-modifying factor enzyme |
IPR016187 |
C-type lectin fold |
Pathway ID | Pathway Term | Pathway Source |
---|---|---|
hsa04142 |
Lysosome |
KEGG |
UMLS CUI | UMLS Term |
---|---|
C0026769 |
Multiple Sclerosis |
C0268263 |
Multiple Sulfatase Deficiency Disease |
C1384666 |
Hearing Impairment |
C1720864 |
Sulfatidosis, Juvenile, Austin Type |
Tissue | Cell Type |
---|---|
breast |
myoepithelial cells |
bronchus |
respiratory epithelial cells |
colon |
endothelial cells |
fallopian tube |
glandular cells |
nasopharynx |
respiratory epithelial cells |
smooth muscle |
smooth muscle cells |
soft tissue |
peripheral nerve |
Pubmed ID | Author | Year | Title |
---|---|---|---|
22617121 |
Ouandaogo et al. |
2012 |
Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation |
Gene Symbol | Entrez ID | Uniprot ID | Score |
---|---|---|---|
HSD17B10 |
3028 |
Q99714 |
0.55 |
COL4A6 |
1288 |
Q14031 |
0.49 |
LAMP1 |
3916 |
P11279 |
0.55 |
ARSA |
410 |
P15289 |
0.63 |
IDS |
3423 |
P22304 |
0.63 |
TAZ |
6901 |
Q16635 |
0.63 |
CTRC |
11330 |
Q99895 |
0.63 |