Protein Description

Gene Symbol SUMF1
Entrez ID 285362
Uniprot ID Q8NBK3
Description sulfatase modifying factor 1
Chromosomal Location chr3: 3,700,814-4,467,281
Ontology GO ID GO Term Definition Evidence

BP

GO:0006687

glycosphingolipid metabolic process

The chemical reactions and pathways involving glycosphingolipids, any compound with residues of sphingoid and at least one monosaccharide.

TAS

BP

GO:0043687

post-translational protein modification

The process of covalently altering one or more amino acids in a protein after the protein has been completely translated and released from the ribosome.

TAS

BP

GO:0055114

oxidation-reduction process

A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.

IEA

CC

GO:0005783

endoplasmic reticulum

The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).

IBA

CC

GO:0005788

endoplasmic reticulum lumen

The volume enclosed by the membranes of the endoplasmic reticulum.

TAS

MF

GO:0016491

oxidoreductase activity

Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.

TAS

MF

GO:0042803

protein homodimerization activity

Interacting selectively and non-covalently with an identical protein to form a homodimer.

IEA

MF

GO:0046872

metal ion binding

Interacting selectively and non-covalently with any metal ion.

IEA

Domain ID Description

IPR005532

Sulfatase-modifying factor enzyme

IPR016187

C-type lectin fold

Pathway ID Pathway Term Pathway Source

hsa04142

Lysosome

KEGG

UMLS CUI UMLS Term

C0026769

Multiple Sclerosis

C0268263

Multiple Sulfatase Deficiency Disease

C1384666

Hearing Impairment

C1720864

Sulfatidosis, Juvenile, Austin Type

Tissue Cell Type

breast

myoepithelial cells

bronchus

respiratory epithelial cells

colon

endothelial cells

fallopian tube

glandular cells

nasopharynx

respiratory epithelial cells

smooth muscle

smooth muscle cells

soft tissue

peripheral nerve

No databases found.

Pubmed ID Author Year Title

22617121

Ouandaogo et al.

2012

Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation

Gene Symbol Entrez ID Uniprot ID Score

HSD17B10

3028

Q99714

0.55

COL4A6

1288

Q14031

0.49

LAMP1

3916

P11279

0.55

ARSA

410

P15289

0.63

IDS

3423

P22304

0.63

TAZ

6901

Q16635

0.63

CTRC

11330

Q99895

0.63