Gene Symbol | SLC26A11 |
Entrez ID | 284129 |
Uniprot ID | Q86WA9 |
Description | solute carrier family 26 (anion exchanger), member 11 |
Chromosomal Location | chr17: 80,219,699-80,253,500 |
Ontology | GO ID | GO Term | Definition | Evidence |
---|---|---|---|---|
BP |
GO:0008272 |
sulfate transport |
The directed movement of sulfate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
IDA |
BP |
GO:0015701 |
bicarbonate transport |
The directed movement of bicarbonate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
IBA |
BP |
GO:0019532 |
oxalate transport |
The directed movement of oxalate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Oxalate, or ethanedioic acid, occurs in many plants and is highly toxic to animals. |
IEA |
BP |
GO:0042391 |
regulation of membrane potential |
Any process that modulates the establishment or extent of a membrane potential, the electric potential existing across any membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane. |
IBA |
BP |
GO:0051453 |
regulation of intracellular pH |
Any process that modulates the internal pH of a cell, measured by the concentration of the hydrogen ion. |
IBA |
BP |
GO:1902358 |
sulfate transmembrane transport |
The directed movement of sulfate across a membrane. |
IEA |
BP |
GO:1902476 |
chloride transmembrane transport |
The directed movement of chloride across a membrane. |
IBA |
CC |
GO:0005654 |
nucleoplasm |
That part of the nuclear content other than the chromosomes or the nucleolus. |
IDA |
CC |
GO:0005765 |
lysosomal membrane |
The lipid bilayer surrounding the lysosome and separating its contents from the cell cytoplasm. |
IDA |
CC |
GO:0005783 |
endoplasmic reticulum |
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached). |
IDA |
CC |
GO:0005794 |
Golgi apparatus |
A compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack. The Golgi apparatus differs from the endoplasmic reticulum in often having slightly thicker membranes, appearing in sections as a characteristic shallow semicircle so that the convex side (cis or entry face) abuts the endoplasmic reticulum, secretory vesicles emerging from the concave side (trans or exit face). In vertebrate cells there is usually one such organelle, while in invertebrates and plants, where they are known usually as dictyosomes, there may be several scattered in the cytoplasm. The Golgi apparatus processes proteins produced on the ribosomes of the rough endoplasmic reticulum; such processing includes modification of the core oligosaccharides of glycoproteins, and the sorting and packaging of proteins for transport to a variety of cellular locations. Three different regions of the Golgi are now recognized both in terms of structure and function: cis, in the vicinity of the cis face, trans, in the vicinity of the trans face, and medial, lying between the cis and trans regions. |
IDA |
CC |
GO:0005886 |
plasma membrane |
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
IDA |
CC |
GO:0005887 |
integral component of plasma membrane |
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
IBA |
CC |
GO:0016021 |
integral component of membrane |
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
IDA |
CC |
GO:0043231 |
intracellular membrane-bounded organelle |
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane. |
IDA |
CC |
GO:0070062 |
extracellular exosome |
A membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm. |
IDA |
MF |
GO:0005254 |
chloride channel activity |
Enables the facilitated diffusion of a chloride (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism. |
IBA |
MF |
GO:0008271 |
secondary active sulfate transmembrane transporter activity |
Catalysis of the secondary active transfer of sulfate from one side of the membrane to the other. Secondary active transport is catalysis of the transfer of a solute from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Chemiosmotic sources of energy include uniport, symport or antiport. |
IEA |
MF |
GO:0008509 |
anion transmembrane transporter activity |
Enables the transfer of a negatively charged ion from one side of a membrane to the other. |
IDA |
MF |
GO:0015106 |
bicarbonate transmembrane transporter activity |
Enables the transfer of bicarbonate from one side of a membrane to the other. Bicarbonate is the hydrogencarbonate ion, HCO3-. |
IBA |
MF |
GO:0015116 |
sulfate transmembrane transporter activity |
Enables the transfer of sulfate ions, SO4(2-), from one side of a membrane to the other. |
IBA |
MF |
GO:0015301 |
anion:anion antiporter activity |
Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: anion A(out) + anion B(in) = anion A(in) + anion B(out). |
IBA |
MF |
GO:0019531 |
oxalate transmembrane transporter activity |
Enables the transfer of oxalate from one side of the membrane to the other. Oxalate, or ethanedioic acid, occurs in many plants and is highly toxic to animals. |
IBA |
Domain ID | Description |
---|---|
IPR001902 |
SLC26A/SulP transporter |
IPR002645 |
STAS domain |
IPR011547 |
SLC26A/SulP transporter domain |
IPR018045 |
Sulphate anion transporter, conserved site |
Tissue | Cell Type |
---|---|
adrenal gland |
glandular cells |
cervix, uterine |
squamous epithelial cells |
esophagus |
squamous epithelial cells |
oral mucosa |
squamous epithelial cells |
pancreas |
exocrine glandular cells |
prostate |
glandular cells |
skin |
Langerhans |
skin |
melanocytes |
skin |
epidermal cells |
tonsil |
squamous epithelial cells |
vagina |
squamous epithelial cells |
Pubmed ID | Author | Year | Title |
---|---|---|---|
22617121 |
Ouandaogo et al. |
2012 |
Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation |