| Gene Symbol | NUDT7 |
| Entrez ID | 283927 |
| Uniprot ID | P0C024 |
| Description | nudix hydrolase 7 |
| Chromosomal Location | chr16: 77,722,492-77,742,260 |
| Ontology | GO ID | GO Term | Definition | Evidence |
|---|---|---|---|---|
|
BP |
GO:0008150 |
biological_process |
Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end. |
ND |
|
BP |
GO:0009132 |
nucleoside diphosphate metabolic process |
The chemical reactions and pathways involving a nucleoside diphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with diphosphate on the sugar. |
IEA |
|
BP |
GO:0015938 |
coenzyme A catabolic process |
The chemical reactions and pathways resulting in the breakdown of coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester. |
ISS |
|
BP |
GO:0044255 |
cellular lipid metabolic process |
The chemical reactions and pathways involving lipids, as carried out by individual cells. |
TAS |
|
BP |
GO:0046356 |
acetyl-CoA catabolic process |
The chemical reactions and pathways resulting in the breakdown of acetyl-CoA, a derivative of coenzyme A in which the sulfhydryl group is acetylated. |
ISS |
|
BP |
GO:0050873 |
brown fat cell differentiation |
The process in which a relatively unspecialized cell acquires specialized features of a brown adipocyte, an animal connective tissue cell involved in adaptive thermogenesis. Brown adipocytes contain multiple small droplets of triglycerides and a high number of mitochondria. |
IEA |
|
CC |
GO:0005777 |
peroxisome |
A small organelle enclosed by a single membrane, and found in most eukaryotic cells. Contains peroxidases and other enzymes involved in a variety of metabolic processes including free radical detoxification, lipid catabolism and biosynthesis, and hydrogen peroxide metabolism. |
ISS |
|
CC |
GO:0005782 |
peroxisomal matrix |
The volume contained within the membranes of a peroxisome; in many cells the matrix contains a crystalloid core largely composed of urate oxidase. |
TAS |
|
MF |
GO:0000287 |
magnesium ion binding |
Interacting selectively and non-covalently with magnesium (Mg) ions. |
IEA |
|
MF |
GO:0003674 |
molecular_function |
Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions. |
ND |
|
MF |
GO:0003986 |
acetyl-CoA hydrolase activity |
Catalysis of the reaction: acetyl-CoA + H(2)O = acetate + CoA + H(+). |
ISS |
|
MF |
GO:0005102 |
receptor binding |
Interacting selectively and non-covalently with one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function. |
IPI |
|
MF |
GO:0016289 |
CoA hydrolase activity |
Catalysis of the reaction: X-CoA + H2O = X + CoA; X may be any group. |
TAS |
|
MF |
GO:0030145 |
manganese ion binding |
Interacting selectively and non-covalently with manganese (Mn) ions. |
IEA |
|
MF |
GO:0030515 |
snoRNA binding |
Interacting selectively and non-covalently with small nucleolar RNA. |
ISS |
| Domain ID | Description |
|---|---|
|
IPR000059 |
NUDIX hydrolase, NudL, conserved site |
|
IPR000086 |
NUDIX hydrolase domain |
|
IPR015797 |
NUDIX hydrolase domain-like |
| Pathway ID | Pathway Term | Pathway Source |
|---|---|---|
|
hsa04146 |
Peroxisome |
KEGG |
| UMLS CUI | UMLS Term |
|---|---|
|
C0023903 |
Liver Neoplasms |
| Tissue | Cell Type |
|---|---|
|
adrenal gland |
glandular cells |
|
appendix |
glandular cells |
|
breast |
glandular cells |
|
duodenum |
glandular cells |
|
fallopian tube |
glandular cells |
|
gallbladder |
glandular cells |
|
kidney |
cells in tubules |
|
pancreas |
exocrine glandular cells |
|
placenta |
trophoblastic cells |
|
salivary gland |
glandular cells |
|
small intestine |
glandular cells |
|
testis |
Leydig cells |
|
thyroid gland |
glandular cells |
|
urinary bladder |
urothelial cells |
| Pubmed ID | Author | Year | Title |
|---|---|---|---|
|
22617121 |
Ouandaogo et al. |
2012 |
Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation |
| Gene Symbol | Entrez ID | Uniprot ID | Score |
|---|---|---|---|
|
PEX5 |
5830 |
P50542 |
0.49 |
|
CUL1 |
8454 |
Q13616 |
0.63 |