Protein Description

Gene Symbol NUDT7
Entrez ID 283927
Uniprot ID P0C024
Description nudix hydrolase 7
Chromosomal Location chr16: 77,722,492-77,742,260
Ontology GO ID GO Term Definition Evidence

BP

GO:0008150

biological_process

Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.

ND

BP

GO:0009132

nucleoside diphosphate metabolic process

The chemical reactions and pathways involving a nucleoside diphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with diphosphate on the sugar.

IEA

BP

GO:0015938

coenzyme A catabolic process

The chemical reactions and pathways resulting in the breakdown of coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester.

ISS

BP

GO:0044255

cellular lipid metabolic process

The chemical reactions and pathways involving lipids, as carried out by individual cells.

TAS

BP

GO:0046356

acetyl-CoA catabolic process

The chemical reactions and pathways resulting in the breakdown of acetyl-CoA, a derivative of coenzyme A in which the sulfhydryl group is acetylated.

ISS

BP

GO:0050873

brown fat cell differentiation

The process in which a relatively unspecialized cell acquires specialized features of a brown adipocyte, an animal connective tissue cell involved in adaptive thermogenesis. Brown adipocytes contain multiple small droplets of triglycerides and a high number of mitochondria.

IEA

CC

GO:0005777

peroxisome

A small organelle enclosed by a single membrane, and found in most eukaryotic cells. Contains peroxidases and other enzymes involved in a variety of metabolic processes including free radical detoxification, lipid catabolism and biosynthesis, and hydrogen peroxide metabolism.

ISS

CC

GO:0005782

peroxisomal matrix

The volume contained within the membranes of a peroxisome; in many cells the matrix contains a crystalloid core largely composed of urate oxidase.

TAS

MF

GO:0000287

magnesium ion binding

Interacting selectively and non-covalently with magnesium (Mg) ions.

IEA

MF

GO:0003674

molecular_function

Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.

ND

MF

GO:0003986

acetyl-CoA hydrolase activity

Catalysis of the reaction: acetyl-CoA + H(2)O = acetate + CoA + H(+).

ISS

MF

GO:0005102

receptor binding

Interacting selectively and non-covalently with one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.

IPI

MF

GO:0016289

CoA hydrolase activity

Catalysis of the reaction: X-CoA + H2O = X + CoA; X may be any group.

TAS

MF

GO:0030145

manganese ion binding

Interacting selectively and non-covalently with manganese (Mn) ions.

IEA

MF

GO:0030515

snoRNA binding

Interacting selectively and non-covalently with small nucleolar RNA.

ISS

Domain ID Description

IPR000059

NUDIX hydrolase, NudL, conserved site

IPR000086

NUDIX hydrolase domain

IPR015797

NUDIX hydrolase domain-like

Pathway ID Pathway Term Pathway Source

hsa04146

Peroxisome

KEGG

UMLS CUI UMLS Term

C0023903

Liver Neoplasms

Tissue Cell Type

adrenal gland

glandular cells

appendix

glandular cells

breast

glandular cells

duodenum

glandular cells

fallopian tube

glandular cells

gallbladder

glandular cells

kidney

cells in tubules

pancreas

exocrine glandular cells

placenta

trophoblastic cells

salivary gland

glandular cells

small intestine

glandular cells

testis

Leydig cells

thyroid gland

glandular cells

urinary bladder

urothelial cells

No databases found.

Pubmed ID Author Year Title

22617121

Ouandaogo et al.

2012

Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation

Gene Symbol Entrez ID Uniprot ID Score

PEX5

5830

P50542

0.49

CUL1

8454

Q13616

0.63