| Gene Symbol | FAM98B |
| Entrez ID | 283742 |
| Uniprot ID | Q52LJ0 |
| Description | family with sequence similarity 98 member B |
| Chromosomal Location | chr15: 38,454,127-38,487,710 |
| Ontology | GO ID | GO Term | Definition | Evidence |
|---|---|---|---|---|
BP | GO:0006388 | tRNA splicing, via endonucleolytic cleavage and ligation |
Splicing of tRNA substrates via recognition of the folded RNA structure that brings the 5' and 3' splice sites into proximity and cleavage of the RNA at both the 3' and 5' splice sites by an endonucleolytic mechanism, followed by ligation of the exons. | TAS |
CC | GO:0005634 | nucleus |
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. | IDA |
CC | GO:0005654 | nucleoplasm |
That part of the nuclear content other than the chromosomes or the nucleolus. | TAS |
CC | GO:0005737 | cytoplasm |
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. | IDA |
CC | GO:0072669 | tRNA-splicing ligase complex |
A protein complex that catalyzes the ligation of cleaved pre-tRNAs by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. | IDA |
MF | GO:0044822 | poly(A) RNA binding |
Interacting non-covalently with a poly(A) RNA, a RNA molecule which has a tail of adenine bases. | IDA |
| Domain ID | Description |
|---|---|
IPR018797 | Uncharacterised protein family FAM98 |
| UMLS CUI | UMLS Term |
|---|---|
C0024141 | Lupus Erythematosus, Systemic |
| Tissue | Cell Type |
|---|---|
caudate | glial cells |
cerebellum | cells in granular layer |
cerebellum | cells in molecular layer |
cerebellum | Purkinje cells |
cerebral cortex | glial cells |
cerebral cortex | neuronal cells |
epididymis | glandular cells |
fallopian tube | glandular cells |
gallbladder | glandular cells |
heart muscle | myocytes |
hippocampus | glial cells |
hippocampus | neuronal cells |
kidney | cells in tubules |
nasopharynx | respiratory epithelial cells |
pancreas | exocrine glandular cells |
placenta | trophoblastic cells |
stomach | glandular cells |
testis | cells in seminiferous ducts |
urinary bladder | urothelial cells |
| Pubmed ID | Author | Year | Title |
|---|---|---|---|
22951915 | Haozi et al. | 2012 | Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome |
| Gene Symbol | Entrez ID | Uniprot ID | Score |
|---|---|---|---|
RNPEP | 6051 | Q9H4A4 | 0.49 |
ARHGDIA | 396 | P52565 | 0.49 |
EEF1A1 | 1915 | P68104 | 0.49 |
IDE | 3416 | P14735 | 0.49 |
PAFAH1B2 | 5049 | P68402 | 0.49 |
PPP1R8 | 5511 | Q12972 | 0.49 |
VARS | 7407 | P26640 | 0.49 |
EIF4H | 7458 | Q15056 | 0.49 |
TRIM25 | 7706 | Q14258 | 0.49 |
ACTR2 | 10097 | P61160 | 0.49 |
EHD1 | 10938 | Q9H4M9 | 0.49 |
TXN2 | 25828 | Q99757 | 0.49 |
GORASP2 | 26003 | Q9H8Y8 | 0.49 |
YOD1 | 55432 | Q5VVQ6 | 0.49 |
C2orf49 | 79074 | Q9BVC5 | 0.49 |
DDX1 | 1653 | Q92499 | 0.59 |
RTCB | 51493 | Q9Y3I0 | 0.59 |
C14orf166 | 51637 | Q9Y224 | 0.59 |
BMI1 | 648 | P35226 | 0.63 |
CD81 | 975 | P60033 | 0.63 |
HNRNPA1 | 3178 | P09651 | 0.63 |
JUN | 3725 | P05412 | 0.63 |
MCM2 | 4171 | P49736 | 0.63 |
MOV10 | 4343 | Q9HCE1 | 0.63 |
NTRK1 | 4914 | P04629 | 0.63 |
PRKAB1 | 5564 | Q9Y478 | 0.63 |
SGK1 | 6446 | O00141 | 0.63 |
SUMO1 | 7341 | P63165 | 0.63 |
XPO1 | 7514 | O14980 | 0.63 |
CUL3 | 8452 | Q13618 | 0.63 |
KIAA0101 | 9768 | Q15004 | 0.63 |
NXF1 | 10482 | Q9UBU9 | 0.63 |
COPS5 | 10987 | Q92905 | 0.63 |
CAND1 | 55832 | Q86VP6 | 0.63 |
BCKDK | 10295 | O14874 | 0.76 |