| Gene Symbol | CHAMP1 |
| Entrez ID | 283489 |
| Uniprot ID | Q96JM3 |
| Description | chromosome alignment maintaining phosphoprotein 1 |
| Chromosomal Location | chr13: 114,314,513-114,327,328 |
| Ontology | GO ID | GO Term | Definition | Evidence |
|---|---|---|---|---|
|
BP |
GO:0031134 |
sister chromatid biorientation |
The cell cycle process in which sister chromatids establish stable attachments to microtubules emanating from opposite spindle poles. |
IMP |
|
BP |
GO:0034501 |
protein localization to kinetochore |
Any process in which a protein is transported to, or maintained at, the kinetochore. |
IMP |
|
BP |
GO:0035372 |
protein localization to microtubule |
A process in which a protein is transported to, or maintained at, a microtubule. |
IMP |
|
BP |
GO:0051315 |
attachment of mitotic spindle microtubules to kinetochore |
The cell cycle process in which spindle microtubules become physically associated with the proteins making up the kinetochore complex as part of mitotic metaphase plate congression. |
IMP |
|
CC |
GO:0000777 |
condensed chromosome kinetochore |
A multisubunit complex that is located at the centromeric region of a condensed chromosome and provides an attachment point for the spindle microtubules. |
IDA |
|
CC |
GO:0000793 |
condensed chromosome |
A highly compacted molecule of DNA and associated proteins resulting in a cytologically distinct structure. |
IDA |
|
CC |
GO:0005634 |
nucleus |
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
IDA |
|
CC |
GO:0005654 |
nucleoplasm |
That part of the nuclear content other than the chromosomes or the nucleolus. |
IDA |
|
CC |
GO:0005737 |
cytoplasm |
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
IEA |
|
CC |
GO:0005819 |
spindle |
The array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during mitosis or meiosis and serves to move the duplicated chromosomes apart. |
IDA |
|
MF |
GO:0003676 |
nucleic acid binding |
Interacting selectively and non-covalently with any nucleic acid. |
IEA |
|
MF |
GO:0005515 |
protein binding |
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules). |
IPI |
|
MF |
GO:0046872 |
metal ion binding |
Interacting selectively and non-covalently with any metal ion. |
IEA |
| Domain ID | Description |
|---|---|
|
IPR013087 |
Zinc finger C2H2-type |
| Tissue | Cell Type |
|---|---|
|
adrenal gland |
glandular cells |
|
appendix |
glandular cells |
|
appendix |
lymphoid tissue |
|
bone marrow |
hematopoietic cells |
|
breast |
glandular cells |
|
breast |
myoepithelial cells |
|
bronchus |
respiratory epithelial cells |
|
caudate |
glial cells |
|
caudate |
neuronal cells |
|
cerebellum |
cells in granular layer |
|
cerebellum |
cells in molecular layer |
|
cerebellum |
Purkinje cells |
|
cerebral cortex |
glial cells |
|
cerebral cortex |
neuronal cells |
|
cervix, uterine |
glandular cells |
|
cervix, uterine |
squamous epithelial cells |
|
colon |
endothelial cells |
|
colon |
glandular cells |
|
duodenum |
glandular cells |
|
endometrium |
cells in endometrial stroma |
|
endometrium |
glandular cells |
|
epididymis |
glandular cells |
|
fallopian tube |
glandular cells |
|
gallbladder |
glandular cells |
|
heart muscle |
myocytes |
|
hippocampus |
glial cells |
|
hippocampus |
neuronal cells |
|
kidney |
cells in glomeruli |
|
liver |
bile duct cells |
|
lung |
macrophages |
|
lung |
pneumocytes |
|
lymph node |
germinal center cells |
|
lymph node |
non-germinal center cells |
|
nasopharynx |
respiratory epithelial cells |
|
oral mucosa |
squamous epithelial cells |
|
ovary |
ovarian stroma cells |
|
pancreas |
exocrine glandular cells |
|
pancreas |
islets of Langerhans |
|
parathyroid gland |
glandular cells |
|
placenta |
decidual cells |
|
placenta |
trophoblastic cells |
|
prostate |
glandular cells |
|
rectum |
glandular cells |
|
salivary gland |
glandular cells |
|
seminal vesicle |
glandular cells |
|
skeletal muscle |
myocytes |
|
skin |
fibroblasts |
|
skin |
keratinocytes |
|
skin |
Langerhans |
|
skin |
melanocytes |
|
small intestine |
glandular cells |
|
smooth muscle |
smooth muscle cells |
|
soft tissue |
adipocytes |
|
soft tissue |
fibroblasts |
|
spleen |
cells in red pulp |
|
spleen |
cells in white pulp |
|
stomach |
glandular cells |
|
testis |
cells in seminiferous ducts |
|
thyroid gland |
glandular cells |
|
tonsil |
germinal center cells |
|
tonsil |
non-germinal center cells |
|
tonsil |
squamous epithelial cells |
|
urinary bladder |
urothelial cells |
|
vagina |
squamous epithelial cells |
| Pubmed ID | Author | Year | Title |
|---|---|---|---|
|
12734205 |
Wood et al. |
2003 |
The Molecular Phenotype of Polycystic Ovary Syndrome (PCOS) Theca Cells and New Candidate PCOS Genes Defined by Microarray Analysis |
|
22951915 |
Haozi et al. |
2012 |
Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome |
| Gene Symbol | Entrez ID | Uniprot ID | Score |
|---|---|---|---|
|
ZMYM4 |
9202 |
Q5VZL5 |
0.72 |
|
EEF1E1 |
9521 |
O43324 |
0.72 |
|
GTPBP1 |
9567 |
O00178 |
0.72 |
|
TBC1D4 |
9882 |
O60343 |
0.72 |
|
INIP |
58493 |
Q9NRY2 |
0.72 |
|
HDGFRP2 |
84717 |
Q7Z4V5 |
0.72 |
|
MAD2L2 |
10459 |
Q9UI95 |
0.89 |
|
RNF169 |
254225 |
Q8NCN4 |
0.07 |
|
MRE11A |
4361 |
P49959 |
0.49 |
|
TERF2 |
7014 |
Q15554 |
0.49 |
|
TTC4 |
7268 |
O95801 |
0.49 |
|
HIST3H3 |
8290 |
Q16695 |
0.49 |
|
RAD50 |
10111 |
Q92878 |
0.49 |
|
SBDS |
51119 |
Q9Y3A5 |
0.49 |
|
TXLNG |
55787 |
Q9NUQ3 |
0.49 |
|
TRPM8 |
79054 |
Q7Z2W7 |
0.49 |
|
JUN |
3725 |
P05412 |
0.63 |
|
MDC1 |
9656 |
Q14676 |
0.63 |
|
DEF6 |
50619 |
Q9H4E7 |
0.63 |
|
HECW2 |
57520 |
Q9P2P5 |
0.63 |
|
TMEM171 |
134285 |
Q8WVE6 |
0.63 |
|
PIN1 |
5300 |
Q13526 |
0.68 |
|
EXOSC4 |
54512 |
Q9NPD3 |
0.72 |
|
CBX8 |
57332 |
Q9HC52 |
0.72 |
|
ZNF644 |
84146 |
Q9H582 |
0.72 |
|
CDKN2AIPNL |
91368 |
Q96HQ2 |
0.72 |
|
SUMO2 |
6613 |
P61956 |
0.79 |
|
POGZ |
23126 |
Q7Z3K3 |
0.82 |
|
CBX5 |
23468 |
P45973 |
0.83 |
|
CBX1 |
10951 |
P83916 |
0.87 |
|
CBX3 |
11335 |
Q13185 |
0.87 |