| Gene Symbol | GAS2L3 |
| Entrez ID | 283431 |
| Uniprot ID | Q86XJ1 |
| Description | growth arrest specific 2 like 3 |
| Chromosomal Location | chr12: 100,573,683-100,628,286 |
| Ontology | GO ID | GO Term | Definition | Evidence |
|---|---|---|---|---|
BP | GO:0000226 | microtubule cytoskeleton organization |
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins. | IDA |
BP | GO:0030036 | actin cytoskeleton organization |
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins. | IDA |
CC | GO:0005737 | cytoplasm |
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. | IEA |
CC | GO:0005874 | microtubule |
Any of the long, generally straight, hollow tubes of internal diameter 12-15 nm and external diameter 24 nm found in a wide variety of eukaryotic cells; each consists (usually) of 13 protofilaments of polymeric tubulin, staggered in such a manner that the tubulin monomers are arranged in a helical pattern on the microtubular surface, and with the alpha/beta axes of the tubulin subunits parallel to the long axis of the tubule; exist in equilibrium with pool of tubulin monomers and can be rapidly assembled or disassembled in response to physiological stimuli; concerned with force generation, e.g. in the spindle. | IEA |
CC | GO:0015629 | actin cytoskeleton |
The part of the cytoskeleton (the internal framework of a cell) composed of actin and associated proteins. Includes actin cytoskeleton-associated complexes. | IDA |
CC | GO:0015630 | microtubule cytoskeleton |
The part of the cytoskeleton (the internal framework of a cell) composed of microtubules and associated proteins. | IDA |
MF | GO:0003779 | actin binding |
Interacting selectively and non-covalently with monomeric or multimeric forms of actin, including actin filaments. | IDA |
MF | GO:0008017 | microtubule binding |
Interacting selectively and non-covalently with microtubules, filaments composed of tubulin monomers. | IDA |
| Domain ID | Description |
|---|---|
IPR001715 | Calponin homology domain |
IPR003108 | Gas2-related domain |
IPR029932 | GAS2-like protein 3 |
| Tissue | Cell Type |
|---|---|
breast | myoepithelial cells |
cerebral cortex | endothelial cells |
colon | endothelial cells |
heart muscle | myocytes |
kidney | cells in glomeruli |
smooth muscle | smooth muscle cells |
| Pubmed ID | Author | Year | Title |
|---|---|---|---|
22617121 | Ouandaogo et al. | 2012 | Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation |
| Gene Symbol | Entrez ID | Uniprot ID | Score |
|---|---|---|---|
CDCA8 | 55143 | Q53HL2 | 0.56 |
AURKB | 9212 | Q96GD4 | 0.7 |
DCTN1 | 1639 | Q14203 | 0.49 |
SPAST | 6683 | Q9UBP0 | 0.52 |
KIF20A | 10112 | O95235 | 0.52 |
CAPZA2 | 830 | P47755 | 0.63 |
ELAVL1 | 1994 | Q15717 | 0.63 |
MYH9 | 4627 | P35579 | 0.63 |
PPP1CB | 5500 | P62140 | 0.63 |
ABCE1 | 6059 | P61221 | 0.63 |
MYO19 | 80179 | Q96H55 | 0.63 |
CCDC8 | 83987 | Q9H0W5 | 0.63 |
BIRC5 | 332 | O15392 | 0.68 |