Protein Description

Gene Symbol GAS2L3
Entrez ID 283431
Uniprot ID Q86XJ1
Description growth arrest specific 2 like 3
Chromosomal Location chr12: 100,573,683-100,628,286
Ontology GO ID GO Term Definition Evidence

BP

GO:0000226

microtubule cytoskeleton organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins.

IDA

BP

GO:0030036

actin cytoskeleton organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins.

IDA

CC

GO:0005737

cytoplasm

All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

IEA

CC

GO:0005874

microtubule

Any of the long, generally straight, hollow tubes of internal diameter 12-15 nm and external diameter 24 nm found in a wide variety of eukaryotic cells; each consists (usually) of 13 protofilaments of polymeric tubulin, staggered in such a manner that the tubulin monomers are arranged in a helical pattern on the microtubular surface, and with the alpha/beta axes of the tubulin subunits parallel to the long axis of the tubule; exist in equilibrium with pool of tubulin monomers and can be rapidly assembled or disassembled in response to physiological stimuli; concerned with force generation, e.g. in the spindle.

IEA

CC

GO:0015629

actin cytoskeleton

The part of the cytoskeleton (the internal framework of a cell) composed of actin and associated proteins. Includes actin cytoskeleton-associated complexes.

IDA

CC

GO:0015630

microtubule cytoskeleton

The part of the cytoskeleton (the internal framework of a cell) composed of microtubules and associated proteins.

IDA

MF

GO:0003779

actin binding

Interacting selectively and non-covalently with monomeric or multimeric forms of actin, including actin filaments.

IDA

MF

GO:0008017

microtubule binding

Interacting selectively and non-covalently with microtubules, filaments composed of tubulin monomers.

IDA

Domain ID Description

IPR001715

Calponin homology domain

IPR003108

Gas2-related domain

IPR029932

GAS2-like protein 3

No pathways found.

No diseases found.

Tissue Cell Type

breast

myoepithelial cells

cerebral cortex

endothelial cells

colon

endothelial cells

heart muscle

myocytes

kidney

cells in glomeruli

smooth muscle

smooth muscle cells

No databases found.

Pubmed ID Author Year Title

22617121

Ouandaogo et al.

2012

Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation

Gene Symbol Entrez ID Uniprot ID Score

CDCA8

55143

Q53HL2

0.56

AURKB

9212

Q96GD4

0.70

DCTN1

1639

Q14203

0.49

SPAST

6683

Q9UBP0

0.52

KIF20A

10112

O95235

0.52

CAPZA2

830

P47755

0.63

ELAVL1

1994

Q15717

0.63

MYH9

4627

P35579

0.63

PPP1CB

5500

P62140

0.63

ABCE1

6059

P61221

0.63

MYO19

80179

Q96H55

0.63

CCDC8

83987

Q9H0W5

0.63

BIRC5

332

O15392

0.68