| Gene Symbol | GAS2L3 |
| Entrez ID | 283431 |
| Uniprot ID | Q86XJ1 |
| Description | growth arrest specific 2 like 3 |
| Chromosomal Location | chr12: 100,573,683-100,628,286 |
| Ontology | GO ID | GO Term | Definition | Evidence |
|---|---|---|---|---|
|
BP |
GO:0000226 |
microtubule cytoskeleton organization |
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins. |
IDA |
|
BP |
GO:0030036 |
actin cytoskeleton organization |
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins. |
IDA |
|
CC |
GO:0005737 |
cytoplasm |
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
IEA |
|
CC |
GO:0005874 |
microtubule |
Any of the long, generally straight, hollow tubes of internal diameter 12-15 nm and external diameter 24 nm found in a wide variety of eukaryotic cells; each consists (usually) of 13 protofilaments of polymeric tubulin, staggered in such a manner that the tubulin monomers are arranged in a helical pattern on the microtubular surface, and with the alpha/beta axes of the tubulin subunits parallel to the long axis of the tubule; exist in equilibrium with pool of tubulin monomers and can be rapidly assembled or disassembled in response to physiological stimuli; concerned with force generation, e.g. in the spindle. |
IEA |
|
CC |
GO:0015629 |
actin cytoskeleton |
The part of the cytoskeleton (the internal framework of a cell) composed of actin and associated proteins. Includes actin cytoskeleton-associated complexes. |
IDA |
|
CC |
GO:0015630 |
microtubule cytoskeleton |
The part of the cytoskeleton (the internal framework of a cell) composed of microtubules and associated proteins. |
IDA |
|
MF |
GO:0003779 |
actin binding |
Interacting selectively and non-covalently with monomeric or multimeric forms of actin, including actin filaments. |
IDA |
|
MF |
GO:0008017 |
microtubule binding |
Interacting selectively and non-covalently with microtubules, filaments composed of tubulin monomers. |
IDA |
| Domain ID | Description |
|---|---|
|
IPR001715 |
Calponin homology domain |
|
IPR003108 |
Gas2-related domain |
|
IPR029932 |
GAS2-like protein 3 |
| Tissue | Cell Type |
|---|---|
|
breast |
myoepithelial cells |
|
cerebral cortex |
endothelial cells |
|
colon |
endothelial cells |
|
heart muscle |
myocytes |
|
kidney |
cells in glomeruli |
|
smooth muscle |
smooth muscle cells |
| Pubmed ID | Author | Year | Title |
|---|---|---|---|
|
22617121 |
Ouandaogo et al. |
2012 |
Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation |
| Gene Symbol | Entrez ID | Uniprot ID | Score |
|---|---|---|---|
|
CDCA8 |
55143 |
Q53HL2 |
0.56 |
|
AURKB |
9212 |
Q96GD4 |
0.70 |
|
DCTN1 |
1639 |
Q14203 |
0.49 |
|
SPAST |
6683 |
Q9UBP0 |
0.52 |
|
KIF20A |
10112 |
O95235 |
0.52 |
|
CAPZA2 |
830 |
P47755 |
0.63 |
|
ELAVL1 |
1994 |
Q15717 |
0.63 |
|
MYH9 |
4627 |
P35579 |
0.63 |
|
PPP1CB |
5500 |
P62140 |
0.63 |
|
ABCE1 |
6059 |
P61221 |
0.63 |
|
MYO19 |
80179 |
Q96H55 |
0.63 |
|
CCDC8 |
83987 |
Q9H0W5 |
0.63 |
|
BIRC5 |
332 |
O15392 |
0.68 |