BP

GO:0010508

positive regulation of autophagy

Any process that activates, maintains or increases the rate of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm.

IMP

BP

GO:0031333

negative regulation of protein complex assembly

Any process that stops, prevents, or reduces the frequency, rate or extent of protein complex assembly.

IMP

BP

GO:1903061

positive regulation of protein lipidation

Any process that activates or increases the frequency, rate or extent of protein lipidation.

IMP

BP

GO:1903070

negative regulation of ER-associated ubiquitin-dependent protein catabolic process

Any process that stops, prevents or reduces the frequency, rate or extent of ER-associated ubiquitin-dependent protein catabolic process.

IMP

BP

GO:1904153

negative regulation of retrograde protein transport, ER to cytosol

Any process that stops, prevents or reduces the frequency, rate or extent of retrograde protein transport, ER to cytosol.

IMP

BP

GO:1904240

negative regulation of VCP-NPL4-UFD1 AAA ATPase complex assembly

Any process that stops, prevents or reduces the frequency, rate or extent of VCP-NPL4-UFD1 AAA ATPase complex assembly.

IEA

CC

GO:0000139

Golgi membrane

The lipid bilayer surrounding any of the compartments of the Golgi apparatus.

IEA

CC

GO:0005789

endoplasmic reticulum membrane

The lipid bilayer surrounding the endoplasmic reticulum.

IDA

CC

GO:0005886

plasma membrane

The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

IEA

CC

GO:0030868

smooth endoplasmic reticulum membrane

The lipid bilayer surrounding the smooth endoplasmic reticulum.

IEA

CC

GO:0031225

anchored component of membrane

The component of a membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping.

IDA

CC

GO:0036513

Derlin-1 retrotranslocation complex

A protein complex that functions in the retrotranslocation step of ERAD (ER-associated protein degradation), and includes at its core Derlin-1 oligomers forming a retrotranslocation channel.

IDA

CC

GO:0070062

extracellular exosome

A membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.

IDA

MF

GO:0005515

protein binding

Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).

IPI

MF

GO:0043621

protein self-association

Interacting selectively and non-covalently with a domain within the same polypeptide.

IMP

MF

GO:0051117

ATPase binding

Interacting selectively and non-covalently with an ATPase, any enzyme that catalyzes the hydrolysis of ATP.

IPI