BP

GO:0000281

mitotic cytokinesis

A cell cycle process that results in the division of the cytoplasm of a cell after mitosis, resulting in the separation of the original cell into two daughter cells.

IMP

BP

GO:0006886

intracellular protein transport

The directed movement of proteins in a cell, including the movement of proteins between specific compartments or structures within a cell, such as organelles of a eukaryotic cell.

IEA

BP

GO:0006897

endocytosis

A vesicle-mediated transport process in which cells take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle.

IMP

BP

GO:0007032

endosome organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of endosomes.

IMP

BP

GO:0007067

mitotic nuclear division

A cell cycle process comprising the steps by which the nucleus of a eukaryotic cell divides; the process involves condensation of chromosomal DNA into a highly compacted form. Canonically, mitosis produces two daughter nuclei whose chromosome complement is identical to that of the mother cell.

IEA

BP

GO:0016050

vesicle organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a vesicle.

IBA

BP

GO:0016197

endosomal transport

The directed movement of substances into, out of, or mediated by an endosome, a membrane-bounded organelle that carries materials newly ingested by endocytosis. It passes many of the materials to lysosomes for degradation.

IMP

BP

GO:0017038

protein import

The targeting and directed movement of proteins into a cell or organelle. Not all import involves an initial targeting event.

IDA

BP

GO:0036089

cleavage furrow formation

Generation of the cleavage furrow, a shallow groove in the cell surface near the old metaphase plate that marks the site of cytokinesis. This process includes the recruitment and localized activation of signals such as RhoA at the site of the future furrow to ensure that furrowing initiates at the correct site in the cell.

IMP

BP

GO:0044351

macropinocytosis

An endocytosis process that results in the uptake of liquid material by cells from their external environment by the 'ruffling' of the cell membrane to form heterogeneously sized intracellular vesicles called macropinosomes, which can be up to 5 micrometers in size.

IMP

BP

GO:0045806

negative regulation of endocytosis

Any process that stops, prevents, or reduces the frequency, rate or extent of endocytosis.

IDA

BP

GO:0051044

positive regulation of membrane protein ectodomain proteolysis

Any process that activates or increases the frequency, rate or extent of membrane protein ectodomain peptidolysis.

IDA

BP

GO:0097320

membrane tubulation

A modification in a plasma membrane resulting in formation of a tubular invagination.

IDA

BP

GO:2000009

negative regulation of protein localization to cell surface

Any process that stops, prevents, or reduces the frequency, rate or extent of protein localization to the cell surface.

IDA

BP

GO:2000010

positive regulation of protein localization to cell surface

Any process that activates or increases the frequency, rate or extent of protein localization to the cell surface.

IDA

CC

GO:0005768

endosome

A vacuole to which materials ingested by endocytosis are delivered.

IBA

CC

GO:0005829

cytosol

The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

IDA

CC

GO:0016020

membrane

A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.

IDA

CC

GO:0016023

cytoplasmic, membrane-bounded vesicle

A membrane-bounded vesicle found in the cytoplasm of the cell.

IDA

CC

GO:0019898

extrinsic component of membrane

The component of a membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.

IDA

CC

GO:0030659

cytoplasmic vesicle membrane

The lipid bilayer surrounding a cytoplasmic vesicle.

IEA

MF

GO:0035091

phosphatidylinositol binding

Interacting selectively and non-covalently with any inositol-containing glycerophospholipid, i.e. phosphatidylinositol (PtdIns) and its phosphorylated derivatives.

IBA