Gene Symbol | LCLAT1 |
Entrez ID | 253558 |
Uniprot ID | Q6UWP7 |
Description | lysocardiolipin acyltransferase 1 |
Chromosomal Location | chr2: 30,447,226-30,644,225 |
Ontology | GO ID | GO Term | Definition | Evidence |
---|---|---|---|---|
BP |
GO:0006654 |
phosphatidic acid biosynthetic process |
The chemical reactions and pathways resulting in the formation of phosphatidic acid, any derivative of glycerol phosphate in which both the remaining hydroxyl groups of the glycerol moiety are esterified with fatty acids. |
TAS |
BP |
GO:0007275 |
multicellular organism development |
The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult). |
IEA |
BP |
GO:0016024 |
CDP-diacylglycerol biosynthetic process |
The chemical reactions and pathways resulting in the formation of CDP-diacylglycerol, CDP-1,2-diacylglycerol, a substance composed of diacylglycerol in glycosidic linkage with cytidine diphosphate. |
IEA |
BP |
GO:0019432 |
triglyceride biosynthetic process |
The chemical reactions and pathways resulting in the formation of a triglyceride, any triester of glycerol. |
TAS |
BP |
GO:0035965 |
cardiolipin acyl-chain remodeling |
Remodeling the acyl chains of premature (de novo synthesized) cardiolipin (1,3-bis(3-phosphatidyl)glycerol), through sequential deacylation and re-acylation reactions, to generate mature cardiolipin containing high-levels of unsaturated fatty acids. |
TAS |
CC |
GO:0005789 |
endoplasmic reticulum membrane |
The lipid bilayer surrounding the endoplasmic reticulum. |
TAS |
CC |
GO:0016020 |
membrane |
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it. |
IDA |
CC |
GO:0016021 |
integral component of membrane |
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
IEA |
MF |
GO:0003841 |
1-acylglycerol-3-phosphate O-acyltransferase activity |
Catalysis of the reaction: acyl-CoA + 1-acyl-sn-glycerol-3-phosphate = CoA + 1,2-diacyl-sn-glycerol-3-phosphate. |
TAS |
MF |
GO:0008374 |
O-acyltransferase activity |
Catalysis of the transfer of an acyl group to an oxygen atom on the acceptor molecule. |
TAS |
Domain ID | Description |
---|---|
IPR002123 |
Phospholipid/glycerol acyltransferase |
IPR032098 |
Acyltransferase, C-terminal domain |
Pathway ID | Pathway Term | Pathway Source |
---|---|---|
hsa00561 |
Glycerolipid metabolism |
KEGG |
hsa00564 |
Glycerophospholipid metabolism |
KEGG |
hsa01100 |
Metabolic pathways |
KEGG |
Pubmed ID | Author | Year | Title |
---|---|---|---|
22617121 |
Ouandaogo et al. |
2012 |
Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation |
Gene Symbol | Entrez ID | Uniprot ID | Score |
---|---|---|---|
TCTN3 |
26123 |
Q6NUS6 |
0.49 |
ELAVL1 |
1994 |
Q15717 |
0.63 |
RNF2 |
6045 |
Q99496 |
0.63 |
GPR52 |
9293 |
Q9Y2T5 |
0.63 |
TSPAN5 |
10098 |
P62079 |
0.63 |
CHRNA9 |
55584 |
Q9UGM1 |
0.63 |
GOPC |
57120 |
Q9HD26 |
0.63 |
PVRIG |
79037 |
Q6DKI7 |
0.63 |
LNX1 |
84708 |
Q8TBB1 |
0.63 |
PRRT2 |
112476 |
Q7Z6L0 |
0.63 |
LYPD6 |
130574 |
Q86Y78 |
0.63 |
FAM134C |
162427 |
Q86VR2 |
0.63 |