Protein Description

Gene Symbol C6orf89
Entrez ID 221477
Uniprot ID Q6UWU4
Description chromosome 6 open reading frame 89
Chromosomal Location chr6: 36,871,870-36,928,964
Ontology GO ID GO Term Definition Evidence

BP

GO:0042060

wound healing

The series of events that restore integrity to a damaged tissue, following an injury.

IDA

BP

GO:0045787

positive regulation of cell cycle

Any process that activates or increases the rate or extent of progression through the cell cycle.

IDA

BP

GO:0050673

epithelial cell proliferation

The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population. Epithelial cells make up the epithelium, the covering of internal and external surfaces of the body, including the lining of vessels and other small cavities. It consists of cells joined by small amounts of cementing substances.

IDA

BP

GO:1901727

positive regulation of histone deacetylase activity

Any process that activates or increases the frequency, rate or extent of histone deacetylase activity.

IDA

CC

GO:0000139

Golgi membrane

The lipid bilayer surrounding any of the compartments of the Golgi apparatus.

IDA

CC

GO:0005730

nucleolus

A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.

IEA

CC

GO:0005737

cytoplasm

All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

IDA

CC

GO:0005886

plasma membrane

The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

IDA

CC

GO:0016021

integral component of membrane

The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

IEA

CC

GO:0030496

midbody

A thin cytoplasmic bridge formed between daughter cells at the end of cytokinesis. The midbody forms where the contractile ring constricts, and may persist for some time before finally breaking to complete cytokinesis.

IDA

MF

GO:0005515

protein binding

Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).

IPI

No domains found.

No pathways found.

No diseases found.

No tissues found.

No databases found.

Pubmed ID Author Year Title

22951915

Haozi et al.

2012

Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome

Gene Symbol Entrez ID Uniprot ID Score

CNN3

1266

Q15417

0.63

PTRHD1

391356

Q6GMV3

0.63

FBXO6

26270

Q9NRD1

0.63